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busulfan and Preleukemia

busulfan has been researched along with Preleukemia in 5 studies

Preleukemia: Conditions in which the abnormalities in the peripheral blood or bone marrow represent the early manifestations of acute leukemia, but in which the changes are not of sufficient magnitude or specificity to permit a diagnosis of acute leukemia by the usual clinical criteria.

Research Excerpts

ExcerptRelevanceReference
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."7.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
"Diagnosis at time of presentation was refractory anemia with excess of blasts (RAEB) in two patients, RAEB in transformation (RAEB-t) in three, and juvenile chronic myelogenous leukemia (JCML, the pediatric counterpart of adult chronic myelomonocytic leukemia) in the remaining three children."5.29Busulfan, cyclophosphamide and melphalan as conditioning regimen for bone marrow transplantation in children with myelodysplastic syndromes. ( Bonetti, F; Cazzola, M; Locatelli, F; Maserati, E; Paolucci, P; Pedrazzoli, P; Pession, A; Prete, A; Prete, L; Zecca, M, 1994)
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."3.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
"Diagnosis at time of presentation was refractory anemia with excess of blasts (RAEB) in two patients, RAEB in transformation (RAEB-t) in three, and juvenile chronic myelogenous leukemia (JCML, the pediatric counterpart of adult chronic myelomonocytic leukemia) in the remaining three children."1.29Busulfan, cyclophosphamide and melphalan as conditioning regimen for bone marrow transplantation in children with myelodysplastic syndromes. ( Bonetti, F; Cazzola, M; Locatelli, F; Maserati, E; Paolucci, P; Pedrazzoli, P; Pession, A; Prete, A; Prete, L; Zecca, M, 1994)
"Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow."1.27Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gyger, M1
Perreault, C1
Boileau, J1
Aymard, JP1
Bonny, Y1
Lacombe, M1
Lavallee, R1
d'Angelo, G1
Tawil, E1
Stuart, J1
Locatelli, F1
Pession, A1
Bonetti, F1
Maserati, E1
Prete, L1
Pedrazzoli, P1
Zecca, M1
Prete, A1
Paolucci, P1
Cazzola, M1
Nand, S1
Stock, W1
Godwin, J1
Fisher, SG1
Pedersen-Bjergaard, J1
Ersbøll, J1
Sørensen, HM1
Keiding, N1
Larsen, SO1
Philip, P1
Larsen, MS1
Schultz, H1
Nissen, NI1

Trials

1 trial available for busulfan and Preleukemia

ArticleYear
Chemotherapy of the myeloid leukaemias.
    Journal of the Royal College of Physicians of London, 1980, Volume: 14, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Child; Clinical Trials as

1980

Other Studies

4 other studies available for busulfan and Preleukemia

ArticleYear
Restoration of normal hematopoiesis by bone marrow ablation and allogeneic marrow transplantation in a case of Hodgkin's disease therapy-related preleukemia.
    Blood, 1983, Volume: 61, Issue:6

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Hematopoiesis; Hodgkin Disease; Huma

1983
Busulfan, cyclophosphamide and melphalan as conditioning regimen for bone marrow transplantation in children with myelodysplastic syndromes.
    Leukemia, 1994, Volume: 8, Issue:5

    Topics: Adolescent; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocol

1994
Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Busulfan; Cell Transformation, Neoplastic;

1996
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
    Annals of internal medicine, 1985, Volume: 103, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot

1985