busulfan has been researched along with Pregnancy in 156 studies
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Microencephaly and microphthalmia in the embryos/fetuses from rats exposed to busulfan were histopathologically examined." | 7.74 | Microencephaly and microphthalmia in rat fetuses by busulfan. ( Abe, M; Furukawa, S; Ogawa, I; Usuda, K, 2007) |
| "A patient with chronic granulocytic leukemia was treated with Busulfan for the three last months of pregnancy." | 7.65 | [Degenerative retinal conditions after treatment with Busulfan during pregnancy (author's transl)]. ( Lefrancois, A; Saraux, H, 1977) |
| "Both busulfan treatment doses caused earlier occurrence of persistent estrus, with dose-dependence as compared to controls." | 5.33 | Reduction of primordial follicles caused by maternal treatment with busulfan promotes endometrial adenocarcinoma development in donryu rats. ( Maekawa, A; Shirota, M; Taya, K; Watanabe, G; Yoshida, M, 2005) |
| "Microencephaly and microphthalmia in the embryos/fetuses from rats exposed to busulfan were histopathologically examined." | 3.74 | Microencephaly and microphthalmia in rat fetuses by busulfan. ( Abe, M; Furukawa, S; Ogawa, I; Usuda, K, 2007) |
| "Female Wistar rats were treated with busulfan or with solvent on Day 20 of pregnancy." | 3.67 | Effect of prenatal treatment with busulfan on the hypothalamo-pituitary axis, genital tract and testicular histology of prepubertal male rats. ( Barenton, B; Hochereau-de Reviers, MT; Perreau, C; Viguier-Martinez, MC, 1984) |
| "Four patients (21, 41, 13 and 38 years of age) with a history of chronic granulocytic leukemia for 12, 10, 11, and 106 months, respectively, were treated with dimethyl busulfan, cyclophosphamide, 920 rads of total-body irradiation and intravenous marrow infusion from normal, genetically identical twins." | 3.66 | Disappearance of Ph1-positive cells in four patients with chronic granulocytic leukemia after chemotherapy, irradiation and marrow transplantation from an identical twin. ( Boyd, C; Buckner, CD; Cheever, MA; Fefer, A; Glucksberg, H; Ramberg, R; Storb, R; Thomas, ED, 1979) |
| " In rats, Busulfan administered in pregnancy can cause destruction of gonocytes and lack of spermatogenesis in adult male rats." | 3.65 | [Teratogenic damages of the male genital organs]. ( Krause, W, 1976) |
| "A patient with chronic granulocytic leukemia was treated with Busulfan for the three last months of pregnancy." | 3.65 | [Degenerative retinal conditions after treatment with Busulfan during pregnancy (author's transl)]. ( Lefrancois, A; Saraux, H, 1977) |
| "Aspirin (ASS) was the most frequently used drug in 47 of 93 recorded cases (51%)." | 2.39 | Essential thrombocythemia and pregnancy. ( Griesshammer, M; Heimpel, H; Pearson, TC, 1996) |
| "Busulfan is a bifunctional alkylating agent used for myeloablative conditioning and in the treatment of chronic myeloid leukemia due to its ability to cause DNA damage." | 1.56 | Maternal exposure to busulfan reduces the cell number in the somatosensory cortex associated with delayed somatic and reflex maturation in neonatal rats. ( Albuquerque, G; Costa-de-Santana, BJR; Gouveia, HJCB; Lacerda, DC; Manhães-de-Castro, R; Mendonça, CR; Toscano, AE; Visco, DB, 2020) |
| "Busulfan is a chemotherapy drug that has side effects on spermatogonial stem cells (SSC)." | 1.43 | Gonadotoxic effects of busulfan in two strains of mice. ( Bordignon, V; Chemeris, RO; Comim, FV; Glanzner, WG; Gonçalves, PB; Gutierrez, K; Rigo, ML, 2016) |
| "Busulfan was used to induce testicular failure in 3-week-old immature FVB/NJNarl wild-type recipient mice." | 1.38 | Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice. ( Chen, CH; Hsu, MI; Huang, YH; Lai, WF; Tzeng, CR; Wang, CW, 2012) |
| "5 mg/kg/day; n = 10 in each group) for 2 or 4 weeks to assess the optimal administration period for detection of the toxic effects on ovarian morphology." | 1.35 | Collaborative work on evaluation of ovarian toxicity. 5) Two- or four-week repeated-dose studies and fertility study of busulfan in female rats. ( Iwasaki, S; Kudo, S; Masumoto, Y; Miyata, Y; Nishi, M; Sakurada, Y, 2009) |
| "Busulfan was intraperitoneally administered at 10 mg/kg on Days 12, 13 and 14, and the placentas were sampled on Day 13." | 1.34 | Busulfan-induced apoptosis in rat placenta. ( Abe, M; Furukawa, S; Hayashi, S; Ogawa, I; Usuda, K, 2007) |
| "Both busulfan treatment doses caused earlier occurrence of persistent estrus, with dose-dependence as compared to controls." | 1.33 | Reduction of primordial follicles caused by maternal treatment with busulfan promotes endometrial adenocarcinoma development in donryu rats. ( Maekawa, A; Shirota, M; Taya, K; Watanabe, G; Yoshida, M, 2005) |
| " However, because the steepness of the dose-response curves indicates that direct administration of busulfan is not ideal for this purpose, 15 mg busulfan kg(-1) was administered to pregnant females at various times between day 10." | 1.32 | Dose-response of RAG2-/-/gammac-/- mice to busulfan in preparation for spermatogonial transplantation. ( Betteridge, KJ; Foster, RA; Hahnel, AC; Moisan, AE, 2003) |
| "Pregnancy was diagnosed via a urine pregnancy test and an ultrasound confirmed a viable foetus at 16 weeks." | 1.29 | Pregnancy in a patient receiving busulphan for chronic myeloid leukaemia. ( Ainoon, O; Cheong, SK; Hamidah, NH; Norhaya, MR, 1994) |
| "The busulfan which she was receiving at that time was stopped and amniocentesis revealed a normal karyotype." | 1.27 | Reversible busulfan-induced ovarian failure. ( Milwidsky, A; Rahav, G; Shalev, O, 1987) |
| "Busulfan is a bifunctional alkylating agent that appears to be cytotoxic to slowly proliferating or non-proliferating stem cell compartments, although its specific molecular and cellular mechanisms are unknown." | 1.27 | Toxicological review of busulfan (Myleran). ( Bishop, JB; Wassom, JS, 1986) |
| "Flutamide treatment decreased the weight of accessory sex organs, stimulated the secretion of both LH (+200%) and FSH (+63%) by inhibition of the negative feedback of testosterone; endogenous testosterone secretion was increased by 363%." | 1.27 | Effects of flutamide or of supplementation with testosterone in prepubertal male rats prenatally treated with busulfan. ( Hochereau-de Reviers, MT; Perreau, C; Viguier-Martinez, MC, 1985) |
| "Busulfan has been the drug most widely used during pregnancy, and it appears not to cause fetal malformations when used alone." | 1.26 | Chronic myelocytic leukemia and the myeloproliferative diseases during the child-bearing years. ( Miller, JB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 107 (68.59) | 18.7374 |
| 1990's | 14 (8.97) | 18.2507 |
| 2000's | 20 (12.82) | 29.6817 |
| 2010's | 12 (7.69) | 24.3611 |
| 2020's | 3 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Schain, F | 1 |
| Vago, E | 1 |
| Song, C | 1 |
| He, J | 1 |
| Liwing, J | 1 |
| Löfgren, C | 1 |
| Björkholm, M | 1 |
| Gouveia, HJCB | 1 |
| Manhães-de-Castro, R | 1 |
| Costa-de-Santana, BJR | 1 |
| Mendonça, CR | 1 |
| Albuquerque, G | 1 |
| Visco, DB | 1 |
| Lacerda, DC | 1 |
| Toscano, AE | 1 |
| Luo, Q | 1 |
| Liu, R | 1 |
| Wang, L | 1 |
| Hou, Y | 1 |
| Zhang, H | 1 |
| Zhang, C | 1 |
| Zhu, H | 1 |
| Cui, H | 1 |
| Chang, X | 1 |
| Wang, Z | 1 |
| Vatanen, A | 1 |
| Wilhelmsson, M | 1 |
| Borgström, B | 1 |
| Gustafsson, B | 1 |
| Taskinen, M | 1 |
| Saarinen-Pihkala, UM | 1 |
| Winiarski, J | 1 |
| Jahnukainen, K | 1 |
| Abe, T | 2 |
| Hanazono, Y | 2 |
| Nagao, Y | 2 |
| Romański, M | 1 |
| Baumgart, J | 1 |
| Böhm, S | 1 |
| Główka, FK | 1 |
| Gutierrez, K | 1 |
| Glanzner, WG | 1 |
| Chemeris, RO | 1 |
| Rigo, ML | 1 |
| Comim, FV | 1 |
| Bordignon, V | 1 |
| Gonçalves, PB | 1 |
| Matias, K | 1 |
| Matias, C | 1 |
| Teixeira, H | 1 |
| Freire, AD | 1 |
| Azevedo, A | 1 |
| Okuda, S | 2 |
| Sato, M | 3 |
| Terasako, K | 2 |
| Kako, S | 2 |
| Oshima, K | 2 |
| Kanda, Y | 2 |
| Peranteau, WH | 2 |
| Heaton, TE | 1 |
| Gu, YC | 1 |
| Volk, SW | 1 |
| Bauer, TR | 1 |
| Alcorn, K | 1 |
| Tuschong, LM | 1 |
| Johnson, MP | 1 |
| Hickstein, DD | 1 |
| Flake, AW | 2 |
| Sakurada, Y | 1 |
| Kudo, S | 1 |
| Iwasaki, S | 1 |
| Miyata, Y | 1 |
| Nishi, M | 1 |
| Masumoto, Y | 1 |
| Yuan, Z | 1 |
| Hou, R | 1 |
| Wu, J | 1 |
| Dodo, T | 1 |
| Uchida, K | 1 |
| Hirose, T | 1 |
| Fukuta, T | 1 |
| Kojima, C | 1 |
| Shiraishi, I | 1 |
| Kato, E | 1 |
| Horiba, T | 1 |
| Mineshima, H | 1 |
| Okuda, Y | 1 |
| Maeda, M | 1 |
| Katsutani, N | 1 |
| Hirano, K | 1 |
| Aoki, T | 1 |
| Sakamoto, K | 1 |
| Ashizawa, M | 1 |
| Kikuchi, M | 1 |
| Kimura, SI | 1 |
| Balashov, DN | 1 |
| Papusha, LI | 1 |
| Nazarenko, TA | 1 |
| Trakhtman, PE | 1 |
| Revishvili, NA | 1 |
| Maschan, AA | 1 |
| Persiantseva, MI | 1 |
| Andriutsa, AV | 1 |
| Skorobogatova, EV | 1 |
| Skvortsova, YV | 1 |
| Rumiantsev, AG | 1 |
| Shah, AJ | 1 |
| Masuda, S | 1 |
| Tanaka, Y | 1 |
| Nitta, S | 1 |
| Kitano, Y | 1 |
| Hayashi, S | 3 |
| Chen, CH | 1 |
| Wang, CW | 1 |
| Hsu, MI | 1 |
| Huang, YH | 1 |
| Lai, WF | 1 |
| Tzeng, CR | 1 |
| Ohira, T | 1 |
| Ando, R | 1 |
| Okada, Y | 1 |
| Suzuki, H | 1 |
| Saito, T | 1 |
| Nakazawa, T | 1 |
| Nishihara, K | 1 |
| Yamamoto, S | 1 |
| Nakamura, N | 1 |
| Tamura, K | 1 |
| McClive, PJ | 1 |
| Sinclair, AH | 1 |
| Shirota, M | 2 |
| Soda, S | 1 |
| Katoh, C | 1 |
| Asai, S | 1 |
| Ohta, R | 1 |
| Watanabe, G | 2 |
| Taya, K | 2 |
| Shirota, K | 1 |
| Brinster, CJ | 1 |
| Ryu, BY | 1 |
| Avarbock, MR | 1 |
| Karagenc, L | 1 |
| Brinster, RL | 1 |
| Orwig, KE | 1 |
| Moisan, AE | 1 |
| Foster, RA | 1 |
| Betteridge, KJ | 1 |
| Hahnel, AC | 1 |
| IZUMI, HM | 1 |
| SHERMAN, JL | 1 |
| LOCKE, RV | 1 |
| HORVATH, L | 1 |
| COERS, RJ | 1 |
| DIAMOND, I | 1 |
| ANDERSON, MM | 1 |
| McCREADIE, SR | 1 |
| WHITE, LG | 1 |
| HEMSWORTH, BN | 2 |
| JACKSON, H | 1 |
| MAUSS, HJ | 1 |
| MEYER, K | 1 |
| SULLI, G | 1 |
| HELLER, RH | 1 |
| JONES, HW | 1 |
| BOUNAMEAUX, Y | 1 |
| DURENNE, JM | 1 |
| GRUENWALD, H | 1 |
| TAUB, RN | 1 |
| WONG, FM | 1 |
| KIOSSOBLOU, KA | 1 |
| DAMESHEK, W | 1 |
| DENNIS, LH | 1 |
| STEIN, S | 1 |
| EARLL, JM | 1 |
| MAY, RL | 1 |
| ALEKSANDROV, VA | 6 |
| PEST, R | 1 |
| RUIZ REYES, G | 1 |
| TAMAYO PEREZ, R | 1 |
| Johnson, J | 1 |
| Canning, J | 1 |
| Kaneko, T | 1 |
| Pru, JK | 1 |
| Tilly, JL | 1 |
| Yoshida, M | 1 |
| Maekawa, A | 1 |
| Ashizuka, S | 1 |
| Furukawa, S | 2 |
| Usuda, K | 2 |
| Abe, M | 2 |
| Ogawa, I | 2 |
| Naruse, T | 1 |
| Takahara, M | 1 |
| Takagi, M | 1 |
| Ogino, T | 4 |
| Pozhidaev, EA | 2 |
| Light, AE | 1 |
| Dugdale, M | 1 |
| Fort, AT | 1 |
| Sobis, H | 3 |
| Vandeputte, M | 3 |
| Viguier-Martinez, MC | 2 |
| Hochereau-de Reviers, MT | 3 |
| Barenton, B | 1 |
| Perreau, C | 2 |
| O'Reilly, RJ | 1 |
| Wollinger, F | 1 |
| Szentcsíki, M | 1 |
| Brenner, F | 1 |
| Balogh, C | 1 |
| Hites, L | 1 |
| Cheever, MA | 2 |
| Fefer, A | 2 |
| Greenberg, PD | 1 |
| Appelbaum, F | 1 |
| Armitage, JO | 1 |
| Buckner, CD | 3 |
| Sale, GE | 1 |
| Storb, R | 3 |
| Witherspoon, RP | 1 |
| Thomas, ED | 2 |
| Norhaya, MR | 1 |
| Cheong, SK | 1 |
| Hamidah, NH | 1 |
| Ainoon, O | 1 |
| Wiebe, VJ | 1 |
| Sipila, PE | 1 |
| Hirshfield, AN | 1 |
| Goldman, JM | 1 |
| Boujrad, N | 1 |
| Carreau, S | 1 |
| Sanders, JE | 1 |
| Hawley, J | 1 |
| Levy, W | 1 |
| Gooley, T | 1 |
| Deeg, HJ | 1 |
| Doney, K | 1 |
| Sullivan, K | 1 |
| Witherspoon, R | 1 |
| Appelbaum, FR | 1 |
| Borgna-Pignatti, C | 1 |
| Marradi, P | 1 |
| Rugolotto, S | 1 |
| Marcolongo, A | 1 |
| Griesshammer, M | 1 |
| Heimpel, H | 1 |
| Pearson, TC | 1 |
| Armenta, D | 1 |
| Espallargas, C | 1 |
| Paz, A | 1 |
| Rodríguez Martorel, J | 1 |
| Ladines, R | 1 |
| Alvarez, C | 1 |
| Román, J | 1 |
| Andrés, P | 1 |
| Jiang, FX | 1 |
| Kaaja, RJ | 1 |
| Leinonen, PJ | 1 |
| Check, ML | 1 |
| Brown, T | 1 |
| Check, JH | 1 |
| Randi, ML | 1 |
| Rossi, C | 1 |
| Fabris, F | 1 |
| Girolami, A | 1 |
| Nakagawa, S | 1 |
| Saburi, S | 1 |
| Yamanouchi, K | 2 |
| Tojo, H | 1 |
| Tachi, C | 1 |
| Wright, CA | 1 |
| Tefferi, A | 1 |
| Classen, CF | 1 |
| Schulz, AS | 1 |
| Sigl-Kraetzig, M | 1 |
| Hoffmann, GF | 1 |
| Simmonds, HA | 1 |
| Fairbanks, L | 1 |
| Debatin, KM | 1 |
| Friedrich, W | 1 |
| Krause, W | 3 |
| Schein, PS | 1 |
| Winokur, SH | 1 |
| Vanhems, E | 4 |
| Bousquet, J | 3 |
| Dubuisson, L | 1 |
| Busquet, J | 1 |
| Wardhaugh, AA | 1 |
| Saraux, H | 1 |
| Lefrancois, A | 1 |
| Boros, SJ | 1 |
| Reynolds, JW | 1 |
| Abramovici, A | 1 |
| Shaklai, M | 1 |
| Pinkhas, J | 1 |
| Bell, R | 1 |
| Sullivan, JR | 1 |
| Hurley, TH | 1 |
| D'Apice, AJ | 1 |
| Kincaid-Smith, P | 1 |
| Boyd, C | 1 |
| Ramberg, R | 1 |
| Glucksberg, H | 1 |
| Schaison, G | 1 |
| Jacquillat, C | 1 |
| Auclerc, G | 1 |
| Weil, M | 1 |
| Merchant-Larios, H | 1 |
| Coello, J | 1 |
| Jaffe, N | 1 |
| Tencé, M | 2 |
| Drosdowsky, M | 1 |
| Lowenthal, MN | 1 |
| Miller, JB | 1 |
| Leibowitz, MR | 1 |
| Derman, DP | 1 |
| Jacobson, R | 1 |
| Stevens, K | 1 |
| Katz, J | 1 |
| Merchant, H | 1 |
| Levine, N | 1 |
| Marsh, DJ | 1 |
| Krause, VW | 1 |
| Drosdowsky, MA | 1 |
| Tence, JF | 1 |
| Barral, I | 1 |
| Ozumba, BC | 1 |
| Obi, GO | 1 |
| Triantafilo, Y | 1 |
| Arteaga, E | 1 |
| Duque, G | 1 |
| Fernández, C | 1 |
| Grebe, G | 1 |
| KATO, H | 2 |
| Reddoch, RB | 1 |
| Pelletier, RM | 1 |
| Barbe, GJ | 1 |
| Armstrong, DT | 1 |
| Yamada, T | 1 |
| Hara, M | 1 |
| Ohba, Y | 1 |
| Inoue, T | 1 |
| Ohno, H | 1 |
| Takahashi, M | 1 |
| Kasuga, F | 1 |
| Saito, S | 1 |
| Matsuyama, S | 1 |
| Murata, T | 1 |
| Shiota, K | 1 |
| Shalev, O | 1 |
| Rahav, G | 1 |
| Milwidsky, A | 1 |
| Pelloux, MC | 1 |
| Picon, R | 1 |
| Gangnerau, MN | 1 |
| Darmoul, D | 1 |
| Fitzgerald, D | 1 |
| Rowe, JM | 1 |
| Heal, J | 1 |
| Szmigiel, Z | 1 |
| Kowalska, J | 1 |
| Szczepaniak, AM | 1 |
| Ohshio, I | 1 |
| Bishop, JB | 1 |
| Wassom, JS | 1 |
| Zöltzer, H | 1 |
| Kato, S | 1 |
| Jansz, GF | 1 |
| Pomerantz, DK | 1 |
| Gaulier, M | 1 |
| Roux, C | 1 |
| Rateau, JG | 2 |
| Armstrong, JG | 1 |
| Hussey, HH | 1 |
| Shepard, TH | 1 |
| Johnson, FD | 1 |
| Nagai, H | 1 |
| Schneider, B | 1 |
| Richards, HG | 1 |
| Spiers, AS | 1 |
| Salmon, M | 1 |
| Orsini, A | 1 |
| Giraud, F | 1 |
| Perrimond, H | 1 |
| Gonggryp, N | 1 |
| Hall, RW | 1 |
| Gomes, WR | 1 |
| Gillet, J | 1 |
| Laporte, P | 1 |
| Stutzman, L | 1 |
| Sokal, JE | 1 |
| Tuchmann-Duplessis, H | 1 |
| Stanzhevskaia, TI | 1 |
| Anisimov, VN | 1 |
| Smalley, RV | 1 |
| Wall, RL | 1 |
| Williams, DW | 1 |
| Uhl, N | 2 |
| Eberle, P | 2 |
| Quellhorst, E | 2 |
| Schmidt, R | 2 |
| Hunstein, W | 2 |
| Kadowaki, J | 1 |
| Moghissi, KS | 1 |
| Loomus, GN | 1 |
| Haddow, A | 1 |
| Nolan, GH | 1 |
| Marks, R | 1 |
| Perez, C | 1 |
| Malakhovskiĭ, VG | 2 |
| Prozorovskiĭ, VB | 1 |
| Maed, K | 1 |
| Pinto-Machado, J | 1 |
| Levina, SE | 1 |
| Kurdovanidze, IL | 1 |
| Kameyama, Y | 1 |
| Sugawara, T | 1 |
| Ogawa, T | 1 |
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| Murakami, Y | 1 |
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| Pugliatti, V | 1 |
| Puglisi Allegra, S | 1 |
| da Silva, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CD133+ Autologue Transplantation to Promote Ovarian Follicles Development in Women With Poor Ovarian Reserve.[NCT01966536] | 0 participants (Actual) | Interventional | 2013-11-30 | Withdrawn (stopped due to Due to fundamental changes in procedures design no patients have been enrolled) | |||
| Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
| A Phase 1, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612, NSC 281612) in Advanced Malignancies[NCT00923520] | Phase 1 | 60 participants (Actual) | Interventional | 2009-03-25 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for busulfan and Pregnancy
| Article | Year |
|---|---|
[MEDICAL THERAPY OF MALIGNANT NEOPLASMS].
Topics: Antimetabolites; Antineoplastic Agents; Antiviral Agents; Blood Transfusion; Busulfan; Chlorambucil; | 1964 |
Allogenic bone marrow transplantation: current status and future directions.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Cell Separation; Cyclophosphamide; Erythroc | 1983 |
Pharmacology of antineoplastic agents in pregnancy.
Topics: Abnormalities, Radiation-Induced; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Emb | 1994 |
Management of chronic myeloid leukaemia.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Blast Crisis; Bone Marrow Transplantation; Busulfan; Ch | 1994 |
Essential thrombocythemia and pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Aspirin; Busulfan; Combined Modality Therapy; Di | 1996 |
A single institutional experience with 43 pregnancies in essential thrombocythemia.
Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulf | 2001 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical a | 1975 |
Late side effects of treatment: skeletal, genetic, central nervous system, and oncogenic.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antineoplastic Agents; Busulfan; Carcinogens; Centra | 1976 |
Use of anticancer drugs during pregnancy.
Topics: Alkylating Agents; Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Busulfan; Chlorambu | 1968 |
1 trial available for busulfan and Pregnancy
| Article | Year |
|---|---|
Survival outcomes in myelofibrosis patients treated with ruxolitinib: A population-based cohort study in Sweden and Norway.
Topics: Aged; Busulfan; Danazol; Disease-Free Survival; Female; Follow-Up Studies; Glucocorticoids; Humans; | 2019 |
146 other studies available for busulfan and Pregnancy
| Article | Year |
|---|---|
Maternal exposure to busulfan reduces the cell number in the somatosensory cortex associated with delayed somatic and reflex maturation in neonatal rats.
Topics: Alkylating Agents; Animals; Behavior, Animal; Body Weight; Busulfan; Cell Count; Female; Maternal Ex | 2020 |
The Effects of Inhibin B in the Chemotherapy Drug-Induced Premature Ovarian Insufficiency Mice and hPMSCs Treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Busulfan; Cyclophosphamide; Disease Models, Animal; Femal | 2020 |
Successful pregnancy and childbirth in a patient with acute lymphoblastic leukaemia after busulfan-based myeloablative conditioning allogeneic haematopoietic stem cell transplantation: a case report.
Topics: Adult; Antineoplastic Agents, Alkylating; Busulfan; Female; Hematopoietic Stem Cell Transplantation; | 2020 |
Ovarian function after allogeneic hematopoietic stem cell transplantation in childhood and adolescence.
Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Cohort Studies; Cyclophosphamide; Female; Fert | 2014 |
Long-term follow-up study on the engraftment of human hematopoietic stem cells in sheep.
Topics: Animals; Busulfan; Cell Proliferation; Female; Fetus; Follow-Up Studies; Hematopoiesis; Hematopoieti | 2014 |
Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats.
Topics: Age Factors; Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Busulfan; Centr | 2015 |
Gonadotoxic effects of busulfan in two strains of mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; Cell Shape; Female; Fertility; Gene Expression | 2016 |
Successful pregnancy following busulfan and cyclophosphamide conditioning and allogeneic bone marrow transplantation for chronic myeloid leukemia.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Humans; Leukemia, Myelogenou | 2008 |
Should busulfan-containing regimen be avoided for young female patients undergoing hematopoietic stem cell transplantation?
Topics: Adult; Busulfan; Female; Hematopoietic Stem Cell Transplantation; Humans; Myeloablative Agonists; Ov | 2009 |
Haploidentical in utero hematopoietic cell transplantation improves phenotype and can induce tolerance for postnatal same-donor transplants in the canine leukocyte adhesion deficiency model.
Topics: Animals; Busulfan; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dogs; Female; Fetal T | 2009 |
Collaborative work on evaluation of ovarian toxicity. 5) Two- or four-week repeated-dose studies and fertility study of busulfan in female rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Busulfan; Drug Administration Schedule; Embr | 2009 |
Generation of mice by transplantation of an adult spermatogonial cell line after cryopreservation.
Topics: Animals; Animals, Newborn; Busulfan; Cell Line; Cell Proliferation; Cryopreservation; Female; Hair C | 2009 |
Increases in discontinuous rib cartilage and fused carpal bone in rat fetuses exposed to the teratogens, busulfan, acetazolamide, vitamin A, and ketoconazole.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Busulfan; Carpal Bones; Cartilage; Diterpenes; | 2010 |
Risks and benefits of ovarian shielding in female patients undergoing TBI: a decision analysis.
Topics: Busulfan; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myelogenous, Chronic, B | 2011 |
Recovery of ovarian function and pregnancy in a patient with AML after myeloablative busulphan-based conditioning regimen.
Topics: Adolescent; Antineoplastic Agents; Busulfan; Child; Combined Modality Therapy; Female; Hematopoietic | 2011 |
Successful pregnancy after busulfan/cytoxan conditioning regimen for AML.
Topics: Adult; Busulfan; Child; Cyclophosphamide; Female; Hematopoietic Stem Cell Transplantation; Humans; L | 2011 |
Maternal administration of busulfan before in utero transplantation of human hematopoietic stem cells enhances engraftments in sheep.
Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Busulfan; DNA Primers; Female; Hematopoie | 2012 |
Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice.
Topics: Animals; Benzothiazoles; Busulfan; Disease Models, Animal; Feasibility Studies; Female; Fertility Pr | 2012 |
Sequence of busulfan-induced neural progenitor cell damage in the fetal rat brain.
Topics: Alkylating Agents; Animals; Apoptosis; Brain; Busulfan; Cell Proliferation; Dose-Response Relationsh | 2013 |
Type II and type IX collagen transcript isoforms are expressed during mouse testis development.
Topics: Alkylating Agents; Animals; Busulfan; Chondrocytes; Collagen; Female; Gene Expression Regulation, De | 2003 |
Effects of reduction of the number of primordial follicles on follicular development to achieve puberty in female rats.
Topics: Alkylating Agents; Animals; Busulfan; Estradiol; Female; Follicle Stimulating Hormone; Inhibins; Lut | 2003 |
Restoration of fertility by germ cell transplantation requires effective recipient preparation.
Topics: Alkylating Agents; Animals; Busulfan; Female; Fertility; Germ Cells; Haplotypes; Infertility, Male; | 2003 |
Dose-response of RAG2-/-/gammac-/- mice to busulfan in preparation for spermatogonial transplantation.
Topics: Alkylating Agents; Animals; Busulfan; Cell Death; DNA-Binding Proteins; Dose-Response Relationship, | 2003 |
Myleran in pregnancy; report of a case.
Topics: Busulfan; Leukemia; Leukemia, Myeloid; Pregnancy | 1956 |
Use of busulfan in myelogenous leukemia during pregnancy.
Topics: Busulfan; Female; Fetus; Humans; Leukemia; Leukemia, Myeloid; Pregnancy | 1958 |
[Myleran therapy of leukemia complicating pregnancy].
Topics: Busulfan; Female; Leukemia; Pregnancy; Pregnancy Complications | 1960 |
[Chronic myeloid leukemia during pregnancy successfully treated with busulfan].
Topics: Busulfan; Female; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Pre | 1959 |
Transplacental transmission of busulfan (myleran) in a mother with leukemia. Production of fetal malformation and cytomegaly.
Topics: Busulfan; Congenital Abnormalities; Female; Leukemia; Mothers; Pregnancy; Pregnancy Complications | 1960 |
Busulfan in pregnancy.
Topics: Busulfan; Female; Humans; Leukemia; Pregnancy; Pregnancy Complications | 1962 |
EFFECT OF BUSULPHAN ON THE DEVELOPING OVARY IN THE RAT.
Topics: Animals; Busulfan; Female; Fetus; Humans; Infertility; Infertility, Female; Ovary; Pharmacology; Pre | 1963 |
[COMPARATIVE STUDIES ON THE EFFECT OF THE CYTOSTATIC SUBSTANCES TRENIMON AND MYLERAN ON FETAL RAT OVARIES].
Topics: Animals; Antineoplastic Agents; Busulfan; Female; Fetus; Histology; Humans; Ovary; Pharmacology; Pre | 1964 |
PRODUCTION OF OVARIAN DYSGENESIS IN THE RAT AND HUMAN BY BUSULPHAN.
Topics: Animals; Busulfan; Congenital Abnormalities; Female; Fetus; Humans; Ovarian Diseases; Ovary; Patholo | 1964 |
[A CASE OF LEUKEMIA IN A LACTATING FEMALE: EFFECT OF TREATMENT WITH BUSULFAN ON THE INFANT].
Topics: Breast Feeding; Busulfan; Drug Therapy; Female; Humans; Infant; Infant, Newborn; Lactation; Leukemia | 1964 |
PHYTOHAEMAGGLUTININ IN TREATMENT OF APLASTIC ANAEMIA.
Topics: Anemia; Anemia, Aplastic; Busulfan; Injections; Injections, Intravenous; Phenacetin; Phytohemaggluti | 1965 |
BUSULFAN IN PREGNANCY: REPORT OF A CASE.
Topics: Busulfan; Drug Therapy; Female; Fetus; Humans; Leukemia; Leukemia, Myeloid; Pharmacology; Pregnancy; | 1965 |
BUSULFAN THERAPY OF MYELOCYTIC LEUKEMIA DURING PREGNANCY.
Topics: Busulfan; Drug Therapy; Female; Humans; Leukemia; Leukemia, Myeloid; Pregnancy; Pregnancy Complicati | 1965 |
[THE PATHOGENIC ACTION OF MYELOSAN ON EMBRYOGENESIS].
Topics: Animals; Busulfan; Embryonic Development; Female; Fetus; Humans; Pharmacology; Pregnancy; Rats; Rese | 1964 |
[Pregnancy in a woman with chronic myelocytic leukemia treated with myleran].
Topics: Busulfan; Female; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Pre | 1960 |
Leukemia and pregnancy: observation of a case treated with busulfan (myleran).
Topics: Busulfan; Leukemia; Pregnancy | 1961 |
Germline stem cells and follicular renewal in the postnatal mammalian ovary.
Topics: Aging; Animals; Biomarkers; Busulfan; Cell Count; Cell Differentiation; Cell Division; Female; Gene | 2004 |
Germline stem cells and follicular renewal in the postnatal mammalian ovary.
Topics: Aging; Animals; Biomarkers; Busulfan; Cell Count; Cell Differentiation; Cell Division; Female; Gene | 2004 |
Germline stem cells and follicular renewal in the postnatal mammalian ovary.
Topics: Aging; Animals; Biomarkers; Busulfan; Cell Count; Cell Differentiation; Cell Division; Female; Gene | 2004 |
Germline stem cells and follicular renewal in the postnatal mammalian ovary.
Topics: Aging; Animals; Biomarkers; Busulfan; Cell Count; Cell Differentiation; Cell Division; Female; Gene | 2004 |
Reduction of primordial follicles caused by maternal treatment with busulfan promotes endometrial adenocarcinoma development in donryu rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Atrophy; Busulfan; Endometrial Neoplasms | 2005 |
Busulfan-conditioned bone marrow transplantation results in high-level allogeneic chimerism in mice made tolerant by in utero hematopoietic cell transplantation.
Topics: Animals; Bone Marrow Transplantation; Busulfan; Chimera; Female; Immune Tolerance; Maternal Exposure | 2006 |
Microencephaly and microphthalmia in rat fetuses by busulfan.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Busulfan; Cell C | 2007 |
Busulfan-induced apoptosis in rat placenta.
Topics: Alkylating Agents; Animals; Apoptosis; Busulfan; Female; Fetal Death; Fetal Weight; Injections, Intr | 2007 |
Early morphological changes leading to central polydactyly, syndactyly, and central deficiencies: an experimental study in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; Embryo, Mammalian; Female; Hindlimb; Humans; I | 2007 |
[Characteristics of the disturbance of embryogenesis under the action of myelosan in the early stages of development of the rat].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Cell Differentiation; Embryo Implantation; Embryo, M | 1966 |
[The mechanism of the lethal effect of myelosan on the rat embryo in the postimplantation stage of development].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Embryo Implantation; Embryo, Mammalian; Extraembryon | 1966 |
[Disorder of embryogenesis after the application of myelosan and chloridin on the female and male gametes in the rat].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Embryo, Mammalian; Female; Fetal Death; Gestational | 1966 |
Additional observations on the effects of busulfan on cataract formation, duration of anesthesia, and reproduction in rats.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Busulfan; Cataract; Diet; Female; Male; Pregnancy; Rat | 1967 |
Busulfan treatment of leukemia during pregnancy. Case report and review of the literature.
Topics: Adult; Busulfan; Female; Fetus; Humans; Infant, Newborn; Leukemia; Pregnancy; Pregnancy Complication | 1967 |
Yolk sac-derived malignant tumors develop in the absence of germ cells.
Topics: Animals; Busulfan; Female; Germ Cells; Laparotomy; Mesonephroma; Neoplasms, Germ Cell and Embryonal; | 1983 |
Effect of prenatal treatment with busulfan on the hypothalamo-pituitary axis, genital tract and testicular histology of prepubertal male rats.
Topics: Animals; Busulfan; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hypothalamo | 1984 |
[Normo- and pathocyclia in the female dog. Diagnosis and therapy].
Topics: Animals; Busulfan; Dog Diseases; Dogs; Endometritis; Estrus; Female; Pregnancy; Progesterone Congene | 1984 |
[Pregnancy during busulfan therapy of chronic granulocytic leukemia].
Topics: Abnormalities, Drug-Induced; Adult; Busulfan; Female; Humans; Leukemia, Myeloid; Maternal-Fetal Exch | 1982 |
Treatment of hairy-cell leukemia with chemoradiotherapy and identical-twin bone-marrow transplantation.
Topics: Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Diseases in Twins; Female; Humans; Leukemia | 1982 |
Pregnancy in a patient receiving busulphan for chronic myeloid leukaemia.
Topics: Adult; Busulfan; Female; Humans; Infant, Newborn; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; | 1994 |
Relationship between the supply of primordial follicles and the onset of follicular growth in rats.
Topics: Animals; Busulfan; Female; Maternal-Fetal Exchange; Oocytes; Ovarian Follicle; Pregnancy; Rats; Rats | 1994 |
Evidence for germ cell control of Sertoli cell function in three models of germ cell depletion in adult rat.
Topics: Animals; Busulfan; Cell Count; Cryptorchidism; Culture Media, Conditioned; Female; Follicle Stimulat | 1995 |
Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Graft Rejection; Humans; Imm | 1996 |
Successful pregnancy after bone marrow transplantation for thalassaemia.
Topics: Adult; beta-Thalassemia; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Combined Modality | 1996 |
[Complete cytogenetic remission of chronic myeloid leukemia with low-dose interferon alfa-2b and monthly high-dose busulfan].
Topics: Adult; Antineoplastic Agents, Alkylating; Busulfan; Combined Modality Therapy; Drug Administration S | 1996 |
Behaviour of spermatogonia following recovery from busulfan treatment in the rat.
Topics: Animals; Body Weight; Busulfan; Cell Division; Cell Polarity; Female; Fertility; Injections, Intrape | 1998 |
Successful pregnancies after recurrent abortions in mild essential thrombocythemia.
Topics: Abortion, Habitual; Adult; Aspirin; Busulfan; Female; Humans; Platelet Aggregation Inhibitors; Pregn | 1998 |
Recovery of spermatogenesis and successful conception after bone marrow transplant for acute leukaemia: case report.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Endometriosis; Female; Fertility; Hu | 2000 |
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free | 2000 |
In vitro studies on PGC or PGC-like cells in cultured yolk sac cells and embryonic stem cells of the mouse.
Topics: Alkylating Agents; Animals; Antibodies, Monoclonal; Busulfan; Cell Division; Cell Movement; Cells, C | 2000 |
Successful HLA-identical bone marrow transplantation in a patient with PNP deficiency using busulfan and fludarabine for conditioning.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Family Health | 2001 |
[Teratogenic damages of the male genital organs].
Topics: Abnormalities, Drug-Induced; Adult; Busulfan; Cryptorchidism; Cyproterone; Female; Genitalia, Male; | 1976 |
Serum gonadotropins in the rat after prenatal damage to the testes by busulfan and their reaction to cryptorchidism, castration and administration of testosterone.
Topics: Animals; Busulfan; Castration; Cryptorchidism; Female; Follicle Stimulating Hormone; Gestational Age | 1977 |
[Ultrastructural study of dysgeneic ovaries of rats, resulting from Misulban administration during fetal life].
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Busulfan; Endoplasmic Reticulum; Female; Gonadal | 1975 |
[Pituitary function of dysgenesic femal rats. Studies with grafting method].
Topics: Animals; Busulfan; Female; Fetus; Kidney; Ovary; Pituitary Gland; Pregnancy; Rats; Spleen; Transplan | 1975 |
[Dysgenesic rat ovaries subjected to gonadotrope stimulation].
Topics: Age Factors; Animals; Busulfan; Diethylstilbestrol; Female; Fetus; Mammary Glands, Animal; Ovary; Pr | 1975 |
Embryopathies due to spermatozoal impairment in Xenopus laevis.
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Chlorohydrins; Female; Gamma Rays; Male; Mesylates; | 1978 |
[A clinical and experimental study on teratogenic mechanism of cleft hand, polydactyly and syndactyly (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Fingers; Forelimb; Humans; Male; Pregnancy; | 1979 |
[Degenerative retinal conditions after treatment with Busulfan during pregnancy (author's transl)].
Topics: Adult; Busulfan; Child, Preschool; Female; Humans; Leukemia, Myeloid; Maternal-Fetal Exchange; Pregn | 1977 |
Intrauterine growth retardation following third-trimester exposure to busulfan.
Topics: Adult; Busulfan; Female; Fetus; Humans; Kidney; Leukemia, Myeloid; Pregnancy; Pregnancy Complication | 1977 |
Myeloschisis in a six weeks embryo of a leukemic woman treated by busulfan.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Busulfan; Female; Gestational Age; Humans; Leuke | 1978 |
Some uses of the continuous flow blood separator in the myeloproliferative syndrome.
Topics: Adult; Busulfan; Female; Gangrene; Humans; Infant, Newborn; Leukapheresis; Leukemia, Myeloid; Male; | 1978 |
Disappearance of Ph1-positive cells in four patients with chronic granulocytic leukemia after chemotherapy, irradiation and marrow transplantation from an identical twin.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Child; Chromosomes, Human, 21-22 and Y; Cyclophosphami | 1979 |
Teratoma induction in mice and rats in relation to the age of the visceral yolk sac.
Topics: Age Factors; Animals; Busulfan; Female; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Neop | 1979 |
[Fetal risk of cancer chemotherapy (author's transl)].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Alkaloids; Animals; Antibiotics, Antineop | 1979 |
The effect of busulfan on rat primordial germ cells at the ultrastructural level.
Topics: Animals; Busulfan; Cell Differentiation; Female; Fetus; Gonads; Male; Pregnancy; Rats; Subcellular F | 1979 |
[Androgen activity of dysgenesic rats' testis. Histochemical, ultrastructural studies and radioimmunoassay of testosterone].
Topics: Animals; Busulfan; Female; Glucosephosphate Dehydrogenase; Histocytochemistry; Leydig Cells; Male; M | 1978 |
Yolk sac-derived rat teratomas are not of germ cell origin.
Topics: Animals; Busulfan; Depression, Chemical; Female; Germ Cells; Male; Ovary; Pregnancy; Rats; Teratoma; | 1976 |
Biosynthesis and metabolism of testosterone by Sertoli cell-enriched seminiferous tubules.
Topics: Androgens; Animals; Busulfan; Dihydrotestosterone; Female; Gestational Age; Male; Maternal-Fetal Exc | 1976 |
Chronic myeloid leukaemia in Zambians.
Topics: Adolescent; Adult; Busulfan; Child; Cyclophosphamide; Female; Follow-Up Studies; Humans; Leukemia, M | 1975 |
Chronic myelocytic leukemia and the myeloproliferative diseases during the child-bearing years.
Topics: Aged; Busulfan; Child; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Myeloproliferative Diso | 1976 |
Chronic myeloid leukaemia in South African blacks.
Topics: Adult; Aged; Black People; Busulfan; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middl | 1976 |
Rat gonadal and ovarioan organogenesis with and without germ cells. An ultrastructural study.
Topics: Animals; Busulfan; Embryo, Mammalian; Female; Germ Cells; Gestational Age; Gonads; Male; Microscopy, | 1975 |
Micropuncture study of the fluid composition of 'Sertoli cell-only' seminiferous tubules in rats.
Topics: Animals; Busulfan; Female; Male; Potassium; Pregnancy; Rats; Sertoli Cells; Sodium; Spermatozoa; Tes | 1975 |
[Teratogenic effect of busulfan on testis cells of the rat (postnatal development)].
Topics: Analysis of Variance; Animals; Busulfan; Cell Count; Female; Follicle Stimulating Hormone; Gestation | 1975 |
Biosynthesis and metabolism of testosterone in isolated germ cells of the ray and the ram and in the Sertoli cells of the rat.
Topics: Animals; Busulfan; Female; Fetus; Male; Pregnancy; Progesterone; Rats; Seminiferous Tubules; Sertoli | 1975 |
Successful pregnancy in a patient with chronic myeloid leukemia following therapy with cytotoxic drugs.
Topics: Acetaminophen; Adult; Busulfan; Diazepam; Drug Therapy, Combination; Female; Humans; Leukemia, Myelo | 1992 |
[Pregnancy in a patient with premature ovarian failure secondary to chemotherapy].
Topics: Adult; Amenorrhea; Busulfan; Estrogens; Female; Follicle Stimulating Hormone; Humans; Ovarian Functi | 1991 |
[Experimental study on radial ray deficiency in rat].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Dose-Response Relationship, Drug; Female; Gestationa | 1990 |
Lack of ovarian responsiveness to gonadotropic hormones in infantile rats sterilized with busulfan.
Topics: 1-Methyl-3-isobutylxanthine; Androstenedione; Animals; Busulfan; Cyclic AMP; Estradiol; Female; Foll | 1986 |
[Studies on implantation traces in rats. I. Size, observation period and staining].
Topics: Abortion, Spontaneous; Animals; Busulfan; Embryo Implantation; Female; Fetal Death; Gestational Age; | 1985 |
Role of germ cells and splenocytes in the steroidogenesis of ovarian endocrine cells.
Topics: Animals; Busulfan; Chorionic Gonadotropin; Cytosol; Estradiol; Estrus; Female; Ovary; Ovum; Pregnanc | 1989 |
Reversible busulfan-induced ovarian failure.
Topics: Adult; Amenorrhea; Busulfan; Estradiol; Estrogens, Conjugated (USP); Female; Follicle Stimulating Ho | 1987 |
Effects of busulfan on ovarian folliculogenesis, steroidogenesis and anti-müllerian activity of rat neonates.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Mullerian Hormone; Aromatase; Busulfan; Estradiol; Es | 1988 |
Histological analysis of myleran induced oligodactyly of longitudinal deficiency in rats.
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Fingers; Pregnancy; Rats; Rats, Inbred Strai | 1988 |
Leukapheresis for control of chronic myelogenous leukemia during pregnancy.
Topics: Adult; Busulfan; Female; Humans; Leukapheresis; Leukemia, Myeloid; Pregnancy; Pregnancy Complication | 1986 |
[Effect of busulfan-treated granulocytic leukemia on pregnancy, labor and the somatic condition of the newborn infant].
Topics: Adult; Busulfan; Female; Humans; Infant, Newborn; Labor, Obstetric; Leukemia, Myeloid; Male; Pregnan | 1986 |
Congenital metacarpal fusion associated with polydactyly.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Busulfan; Female; Fingers; Follow-Up | 1987 |
Toxicological review of busulfan (Myleran).
Topics: Animals; Busulfan; Carcinogens; Cell Survival; Female; Hematologic Diseases; Humans; Immunity; Male; | 1986 |
Effects of flutamide or of supplementation with testosterone in prepubertal male rats prenatally treated with busulfan.
Topics: Anilides; Animals; Body Weight; Busulfan; Female; Flutamide; Follicle Stimulating Hormone; Hypothala | 1985 |
Effects of busulfan on the placental labyrinth of the rat.
Topics: Animals; Busulfan; Female; Placenta; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
[An experimental study on the development of myleran-induced oligodactyly in rats].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Cell Differentiation; Female; Gestational Age; Male; | 1985 |
The effect of prenatal treatment with busulfan on in vitro androgen production by testes from rats of various ages.
Topics: Aging; Androgens; Animals; Body Weight; Busulfan; Female; Luteinizing Hormone; Male; Maternal-Fetal | 1985 |
[Effect of Busulfan on the germinal line of the rat embryo].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Fetus; Germ Cells; Gestational Age; Male; Pr | 1970 |
[Differentiation of rat ovary after treatment with Busulfan].
Topics: Animals; Animals, Newborn; Busulfan; Cell Differentiation; Female; Fetus; Ovary; Pregnancy; Rats | 1974 |
[Follicular and glandular maturation of rat ovaries treated with Busulfan].
Topics: Animals; Busulfan; Female; Gonadotropins, Equine; Ovarian Follicle; Ovary; Pregnancy; Rats | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
Editorial: Gynecomastia.
Topics: Age Factors; Antidepressive Agents; Busulfan; Child; Child, Preschool; Digitalis Glycosides; Estroge | 1974 |
Teratogenicity from drugs--an increasing problem.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bact | 1974 |
Pregnancy and concurrent chronic myelogenous leukemia.
Topics: Adult; Busulfan; Colchicine; Female; Gestational Age; Humans; Infant, Newborn; Leukemia, Myeloid; Pr | 1972 |
Effects of transplacentally injected alkylating agents upon development of embryos. Appearance of intrauterine death and mesodermal malformation.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Busulfan; Female; Fetal Death; Mesoderm; Piperazines | 1972 |
[Leukemia in pregnancy (case report)].
Topics: Adult; Blood Transfusion; Busulfan; Female; Gestational Age; Hemorrhagic Disorders; Humans; Infant, | 1973 |
Proceedings: Chronic granulocytic leukaemia in pregnancy.
Topics: Busulfan; Female; Humans; Leukemia, Myeloid; Leukocytosis; Mannitol; Mercaptopurine; Pregnancy; Preg | 1974 |
[Antimetabolites and pregnancy. Normal child born to a mother under treatment 8 years for chronic myeloid leukemia].
Topics: Abortion, Therapeutic; Adolescent; Busulfan; Chronic Disease; Female; Humans; Leukemia, Myeloid; Leu | 1972 |
Testosterone levels in the serum and testes of growing rats following prenatal exposure to busulphan.
Topics: Animals; Body Weight; Busulfan; Female; Injections, Intraperitoneal; Male; Maternal-Fetal Exchange; | 1973 |
[Epididymal changes in the rat after in utero treatment with busulfan].
Topics: Abnormalities, Drug-Induced; Animals; Atrophy; Busulfan; Epididymis; Female; Male; Mitosis; Pregnanc | 1973 |
[The teratogenic effect of busulfan on testis cells of the fetal rat].
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Busulfan; Female; Fetus; Germ Cells; Ges | 1973 |
[The teratogenic risk].
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; | 1968 |
[Effect of myelosan on the chick embryo at various stages of development].
Topics: Abnormalities, Drug-Induced; Animals; Beak; Bone and Bones; Busulfan; Chick Embryo; Eye Abnormalitie | 1969 |
[Selective sterilizing effect of myelosan on the ovaries of rat fetuses].
Topics: Animals; Busulfan; Female; Fetus; Maternal-Fetal Exchange; Ovary; Pregnancy; Rats; Sterilization, Re | 1972 |
Two cases of busulfan toxicity.
Topics: Adrenal Insufficiency; Adult; Busulfan; Female; Humans; Leukemia, Myeloid; Middle Aged; Pigmentation | 1966 |
Busulfan in early pregnancy.
Topics: Adult; Busulfan; Female; Humans; Leukemia, Myeloid; Pregnancy; Pregnancy Complications, Hematologic; | 1966 |
[Myleran therapy in pregnancy. A case contribution with chromosome examination].
Topics: Adult; Busulfan; Cell Division; Cytogenetics; Female; Fetus; Genes; Genetics, Medical; Humans; Infan | 1968 |
Busulfan treatment in pregnancy. A case report with chromosome studies.
Topics: Adult; Busulfan; Chromosome Aberrations; Chromosome Disorders; Female; Humans; Leukemia, Myeloid; Pr | 1969 |
Granulocytic leukemia in pregnancy.
Topics: Adult; Busulfan; Cesarean Section; Chromosome Aberrations; Female; Humans; Infant, Newborn; Karyotyp | 1970 |
Oncology: its scope and prospects.
Topics: Burkitt Lymphoma; Busulfan; Carcinogens; Choriocarcinoma; Climate; DNA Replication; Environment; Fem | 1971 |
Busulfan treatment of leukemia during pregnancy. A case report.
Topics: Adult; Busulfan; Female; Humans; Leukemia, Myeloid; Pregnancy; Pregnancy Complications, Hematologic | 1971 |
[Behavior disorders in rats subjected to the antenatal effects of teratogenic agents].
Topics: Aggression; Animals; Behavior, Animal; Busulfan; Conditioning, Classical; Embryo, Mammalian; Escape | 1969 |
[Range of teratogenic action as an indication of danger in using a medicinal preparation during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Pregnancy; Pregnancy Complications; Pyrimeth | 1970 |
Skeletal malformations of the hand and foot in the rat fetus caused by maternal administration of myleran during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Busulfan; Female; Foot Deformities, Congenital | 1970 |
Influence of prenatal administration of busulfan on the postnatal development of mice. Production of a syndrome including hypoplasia of the thymus.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bone Development; Busulfan; Female; F | 1970 |
[Changes in developing rat gonads following intrauterine exposure to myelosan].
Topics: Animals; Busulfan; Female; Fetal Death; Fetus; Gonads; Male; Organ Size; Ovary; Pregnancy; Rats; Tes | 1971 |
[Superovulation and decidual response of the rat uterus following administration of myelosan at different times before ovulation].
Topics: Animals; Busulfan; Decidua; Female; Ovarian Diseases; Ovulation; Pregnancy; Pregnancy Complications; | 1967 |
[Occurrence of a lethal effect and causes of death of the rat fetus after the administration of myelosan prior to implantation].
Topics: Animals; Busulfan; Embryo Implantation; Female; Fetal Death; Pregnancy; Rats; Time Factors | 1968 |
[The effect of uterine innervation disorders in pregnant rats on the vulnerability of their fetuses to the effects of hyperthermia and myelosan].
Topics: Animals; Busulfan; Denervation; Female; Fetal Diseases; Fetus; Fever; Maternal-Fetal Exchange; Pregn | 1968 |
Effects of myleran on the development of the skeletal system in the rat and mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; Bone Development; Busulfan; Embryo, Mammalian; Female; Mice; P | 1965 |
Analysis of the lethal effect of "Myleran" on rat embryos.
Topics: Animals; Busulfan; Embryo, Mammalian; Female; Palmitic Acids; Pregnancy; Pregnancy, Animal; Rats | 1966 |
The effect of prenatally administered Busulphan on rat gonads.
Topics: Animals; Busulfan; Female; Germ Cells; Gonads; Injections, Intraperitoneal; Male; Pregnancy; Pregnan | 1966 |
[Determination of gonadal changes in the albino rat by means of cytostatic treatment given during intrauterine life. 3. Morphological and functional postpuberal aspects of the gonads].
Topics: Animals; Busulfan; Female; Fetus; Gonads; Infertility, Female; Male; Pregnancy; Pregnancy, Animal; R | 1966 |
[Embryotoxic and teratogenic effect of busulfan (1,4-dimethanosulfonyloxybutane)].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Mice; Pregnancy | 1966 |