busulfan has been researched along with Polycythemia Vera in 159 studies
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited." | 9.19 | Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea. ( Alvarez-Larrán, A; Ancochea, A; Angona, A; Antelo, ML; Bellosillo, B; Besses, C; Burgaleta, C; Cervantes, F; Durán, MA; Ferrer-Marín, F; Gómez, M; Gómez-Casares, MT; Hernández-Boluda, JC; Marcote, B; Martínez-Avilés, L; Martínez-Trillos, A; Mata, MI; Senín, A; Vicente, V; Xicoy, B, 2014) |
| "Hydroxyurea (HU) has traditionally been the first-line treatment for patients with polycythemia vera (PV) or essential thrombocythemia (ET) at high risk for vascular complications." | 8.90 | Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea. ( Newberry, KJ; Sever, M; Verstovsek, S, 2014) |
| "The efficacy of hydroxyurea (HU) in myeloproliferative disorders is well documented." | 7.73 | Safety profile of hydroxyurea in the treatment of patients with Philadelphia-negative chronic myeloproliferative disorders. ( Fabris, F; Girolami, A; Luzzatto, G; Randi, ML; Ruzzon, E; Tezza, F, 2005) |
| " She had a history of polycythemia vera and had been treated with a daily dose of 500mg hydroxyurea (HU) for six years." | 7.72 | Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera. ( Iwata, K; Nakano, M; Ogawa, H; Ogura, S; Seki, K; Tasaka, T; Yokota, K, 2003) |
| "In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%." | 7.69 | Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996) |
| "Over a 19-year period, a patient with polycythemia vera who had undergone a splenectomy received six courses of busulfan for recurrent thrombocytosis." | 7.65 | Erythroleukemia-like syndrome due to busulfan toxicity in polycythemia vera. ( Kim, HC; Lindenbaum, J; Pezzimenti, JF, 1976) |
| "The effect of busulfan therapy on the activity of oncornavirus-like particles and chromosome patterns in patients with polycythemia vera and essential thrombocythemia was studied." | 7.65 | Effect of busulfan on oncornavirus-like activity in platelets and chromosomes in polycythemia vera and essential thrombocythemia. ( Brodsky, I; Erlick, BJ; Fuscaldo, AA; Fuscaldo, KE, 1977) |
| "Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited." | 5.19 | Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea. ( Alvarez-Larrán, A; Ancochea, A; Angona, A; Antelo, ML; Bellosillo, B; Besses, C; Burgaleta, C; Cervantes, F; Durán, MA; Ferrer-Marín, F; Gómez, M; Gómez-Casares, MT; Hernández-Boluda, JC; Marcote, B; Martínez-Avilés, L; Martínez-Trillos, A; Mata, MI; Senín, A; Vicente, V; Xicoy, B, 2014) |
| "In the clinical phase studies, ranimustine showed very excellent responses against chronic myelogenous leukemia, polycythemia vera and thrombocythemia, and moderate responses against lymphoma or myeloma." | 5.06 | [Ranimustine]. ( Masaoka, T, 1990) |
| "Hydroxyurea (HU) has traditionally been the first-line treatment for patients with polycythemia vera (PV) or essential thrombocythemia (ET) at high risk for vascular complications." | 4.90 | Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea. ( Newberry, KJ; Sever, M; Verstovsek, S, 2014) |
| "A 57-year-old male who had suffered from polycythemia vera (PV) and had been treated with pipobroman, carbazilquinon and busulfan for ten years presented with fever." | 4.78 | [Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. ( Hino, K; Koike, T; Sakashita, A; Sato, S; Tomoyasu, S; Tsuruoka, N, 1992) |
| "The efficacy of hydroxyurea (HU) in myeloproliferative disorders is well documented." | 3.73 | Safety profile of hydroxyurea in the treatment of patients with Philadelphia-negative chronic myeloproliferative disorders. ( Fabris, F; Girolami, A; Luzzatto, G; Randi, ML; Ruzzon, E; Tezza, F, 2005) |
| " She had a history of polycythemia vera and had been treated with a daily dose of 500mg hydroxyurea (HU) for six years." | 3.72 | Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera. ( Iwata, K; Nakano, M; Ogawa, H; Ogura, S; Seki, K; Tasaka, T; Yokota, K, 2003) |
| "In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%." | 3.69 | Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996) |
| "A 77-year-old male, who had been treated with carboquone and busulfan for polycythemia vera (PV), developed myelodysplastic syndrome (MDS) 8 years later." | 3.68 | [Polycythemia vera terminating in myelodysplastic syndrome]. ( Abe, T; Kimura, S; Kobayashi, Y; Kondo, M; Maruo, N; Ozawa, M; Tanaka, R; Uoshima, N; Yoshida, Y, 1990) |
| "Over a 19-year period, a patient with polycythemia vera who had undergone a splenectomy received six courses of busulfan for recurrent thrombocytosis." | 3.65 | Erythroleukemia-like syndrome due to busulfan toxicity in polycythemia vera. ( Kim, HC; Lindenbaum, J; Pezzimenti, JF, 1976) |
| "The effect of busulfan therapy on the activity of oncornavirus-like particles and chromosome patterns in patients with polycythemia vera and essential thrombocythemia was studied." | 3.65 | Effect of busulfan on oncornavirus-like activity in platelets and chromosomes in polycythemia vera and essential thrombocythemia. ( Brodsky, I; Erlick, BJ; Fuscaldo, AA; Fuscaldo, KE, 1977) |
| "Controlled studies are needed to confirm the clinical outcome value of twice-daily vs once-daily aspirin dosing and the therapeutic role of pegylated interferons and direct oral anticoagulants." | 2.66 | Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2020) |
| "Treatment with busulfan or interferon-α is usually effective in hydroxyurea failures." | 2.48 | Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management. ( Tefferi, A, 2012) |
| "The principal risks of essential thrombocythemia include thrombosis, major hemorrhage, and conversion to leukemia or myelofibrosis." | 2.41 | Therapeutic options for essential thrombocythemia and polycythemia vera. ( Solberg, LA, 2002) |
| "Busulfan was temporally effective in controlling the neutrophil count." | 2.40 | Transition of polycythemia vera to chronic neutrophilic leukemia. ( Endo, M; Fujita, K; Harada, H; Higuchi, T; Mori, H; Niikura, H; Oba, R; Omine, M, 1999) |
| "Fifty consecutive patients with thrombocythemia (35 men and 15 women) were diagnosed as primary thrombocythemia (PT) in 30 and thrombocythemia associated with polycythemia vera (PV) in 20." | 2.39 | Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. ( Lindemans, J; Michiels, JJ; van Genderen, PJ; van Vliet, HH, 1996) |
| "The case of a patient with myelofibrosis who developed polycythaemia vera after corticosteroid therapy, splenectomy and Busulphan therapy is reported." | 2.37 | [Onset of polycythemia in idiopathic myelofibrosis. Description of a clinical case and review of the literature]. ( Bizzi, B; Leone, G; Marra, R; Pagano, L; Rabbitti, C; Storti, S; Teofili, L, 1988) |
| "Risk of thrombosis is higher in JAK2-mutated ET." | 1.51 | Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019) |
| "This study indicates that in myelofibrosis, NMA regimens result in high engraftment failure rates." | 1.42 | Effect of conditioning regimens on graft failure in myelofibrosis: a retrospective analysis. ( Broers, AE; Janssen, JJ; Raymakers, R; Slot, S; Smits, K; Te Boekhorst, PA; van de Donk, NW; Witte, BI; Zweegman, S, 2015) |
| "Hydroxyurea and myelosan were mostly used as cytostatic drugs while erythrocyte mass transfusions and hemoexfusions (phlebotomy)--for life-support." | 1.32 | [Choice of therapy and overall survival in patients with chronic myeloproliferative diseases]. ( Pop, VP; Rukavitsyn, OA; Seriakov, AP, 2004) |
| "He developed acute megakaryoblastic leukemia 17 years after the initial diagnosis of PV." | 1.31 | Megakaryoblastic transformation of polycythemia vera with hypercalcemia. ( Iwasaki, H; Kurosawa, M, 2002) |
| "Hydroxyurea, which is a cell-cycle-specific agent, probably exacerbates the periodicity which may be present in some patients with myeloproliferative disease." | 1.31 | Hydroxyurea and periodicity in myeloproliferative disease. ( Bennett, M; Grunwald, AJ, 2001) |
| "Bleeding was observed in 57% of patients with OMF, 23% with PV, 20% with chronic phase CML, and 16% with ET." | 1.28 | Incidence and clinical risk factors for bleeding and thrombotic complications in myeloproliferative disorders. A retrospective analysis of 260 patients. ( Daum, I; Jamin, H; Schneider, W; Wehmeier, A, 1991) |
| "Only deaths from acute leukaemia and myelofibrosis were significantly increased above the normal population incidence." | 1.27 | Treatment of primary proliferative polycythaemia by venesection and low dose busulphan: retrospective study from one centre. ( Messinezy, M; Pearson, TC; Prochazka, A; Wetherley-Mein, G, 1985) |
| "A case of typical idiopathic myelofibrosis turning into polycythaemia vera 6 years after diagnosis is reported." | 1.27 | [Development of polycythemia vera during chronic idiopathic myelofibrosis]. ( Covaz, E; Mazzanti, G; Paladini, G; Tosato, F, 1985) |
| "The pregnancy has no adverse effect on the course of the mother's hematologic disease." | 1.26 | Chronic myelocytic leukemia and the myeloproliferative diseases during the child-bearing years. ( Miller, JB, 1976) |
| "Chronic granulocytic leukemia developed in a 59-year-old woman who had previously received a total of 21 mCi -32P for polycythemia vera." | 1.25 | Polycythemia vera treated with -32p and myleran: development of chronic granulocytic leukemia with chromosomal abnormalities in one patient. ( Sandnes, K; Staven, P; VAN DER Hagen, CB; Vogt, E, 1975) |
| "It is concluded that the development of fibrosing alveolitis may be related to individual genetic or immunological factors rather than to busulphan dosage." | 1.25 | Lung function in patients receiving busulphan. ( Littler, WA; Ogilvie, C, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 116 (72.96) | 18.7374 |
| 1990's | 22 (13.84) | 18.2507 |
| 2000's | 10 (6.29) | 29.6817 |
| 2010's | 9 (5.66) | 24.3611 |
| 2020's | 2 (1.26) | 2.80 |
| Authors | Studies |
|---|---|
| Tefferi, A | 6 |
| Barbui, T | 4 |
| Kuriakose, ET | 1 |
| Gjoni, S | 1 |
| Wang, YL | 1 |
| Baumann, R | 1 |
| Jones, AV | 1 |
| Cross, NC | 1 |
| Silver, RT | 1 |
| Randi, ML | 3 |
| Santarossa, C | 1 |
| Peroni, E | 1 |
| Cosi, E | 1 |
| Duner, E | 1 |
| Bertozzi, I | 1 |
| Fabris, F | 2 |
| Sever, M | 1 |
| Newberry, KJ | 1 |
| Verstovsek, S | 1 |
| Alvarez-Larrán, A | 1 |
| Martínez-Avilés, L | 1 |
| Hernández-Boluda, JC | 1 |
| Ferrer-Marín, F | 1 |
| Antelo, ML | 1 |
| Burgaleta, C | 1 |
| Mata, MI | 1 |
| Xicoy, B | 1 |
| Martínez-Trillos, A | 1 |
| Gómez-Casares, MT | 1 |
| Durán, MA | 1 |
| Marcote, B | 1 |
| Ancochea, A | 1 |
| Senín, A | 1 |
| Angona, A | 1 |
| Gómez, M | 1 |
| Vicente, V | 1 |
| Cervantes, F | 1 |
| Bellosillo, B | 1 |
| Besses, C | 1 |
| Slot, S | 1 |
| Smits, K | 1 |
| van de Donk, NW | 1 |
| Witte, BI | 1 |
| Raymakers, R | 2 |
| Janssen, JJ | 1 |
| Broers, AE | 1 |
| Te Boekhorst, PA | 1 |
| Zweegman, S | 1 |
| Nazha, A | 1 |
| Gerds, AT | 1 |
| Begna, K | 1 |
| Abdelatif, A | 1 |
| Schwager, S | 1 |
| Hanson, C | 1 |
| Pardanani, A | 1 |
| Kurosawa, M | 1 |
| Iwasaki, H | 1 |
| Michiels, JJ | 3 |
| Berneman, Z | 1 |
| Schroyens, W | 1 |
| van Urk, H | 1 |
| Deeg, HJ | 1 |
| Gooley, TA | 1 |
| Flowers, ME | 1 |
| Sale, GE | 1 |
| Slattery, JT | 1 |
| Anasetti, C | 1 |
| Chauncey, TR | 1 |
| Doney, K | 1 |
| Georges, GE | 1 |
| Kiem, HP | 1 |
| Martin, PJ | 1 |
| Petersdorf, EW | 1 |
| Radich, J | 1 |
| Sanders, JE | 1 |
| Sandmaier, BM | 1 |
| Warren, EH | 1 |
| Witherspoon, RP | 1 |
| Storb, R | 1 |
| Appelbaum, FR | 1 |
| WALD, N | 1 |
| HOSHINO, T | 1 |
| SEARS, ME | 1 |
| LOUIS, J | 1 |
| ROUQUES, L | 1 |
| FRICK, PG | 1 |
| KILLMANN, SA | 1 |
| CRONKITE, EP | 1 |
| KIRCHMAYER, S | 2 |
| SZARBINSKI, T | 1 |
| BLUM, M | 1 |
| PAREKH, JG | 1 |
| SHARMA, RS | 1 |
| SHAH, KM | 1 |
| TATEYAMA, M | 1 |
| DOCTOR, F | 1 |
| LEHOCZKY, D | 1 |
| BECKER, H | 1 |
| WOODLIFF, HJ | 1 |
| REICHARD, H | 1 |
| BRODSKY, I | 7 |
| SHVEDSKII, BP | 1 |
| NIKOLAEVA, NV | 1 |
| MAURICE, PA | 2 |
| BOREL, Y | 1 |
| COLLET, RA | 1 |
| Yokota, K | 1 |
| Tasaka, T | 1 |
| Iwata, K | 1 |
| Ogawa, H | 1 |
| Nakano, M | 1 |
| Seki, K | 1 |
| Ogura, S | 1 |
| Rukavitsyn, OA | 1 |
| Pop, VP | 1 |
| Seriakov, AP | 1 |
| Ruzzon, E | 1 |
| Luzzatto, G | 1 |
| Tezza, F | 1 |
| Girolami, A | 2 |
| Fuscaldo, AA | 2 |
| Erlick, BJ | 2 |
| Fuscaldo, KE | 2 |
| Charbord, P | 1 |
| Neel, H | 1 |
| Caillou, B | 1 |
| Eydoux, P | 1 |
| Gardet, P | 1 |
| Parmentier, C | 1 |
| Krogsgaard-Jensen, A | 1 |
| Djaldetti, M | 1 |
| Bessler, H | 1 |
| Kimche, D | 1 |
| Berliner, S | 1 |
| Shoenfeld, Y | 1 |
| Shaklai, M | 2 |
| Pinkhas, J | 1 |
| Najean, Y | 1 |
| Dresch, C | 1 |
| Dalwiche, F | 1 |
| Unger, J | 1 |
| Strijckmans, P | 1 |
| Monsieur, R | 1 |
| Bellens, R | 1 |
| Brandt, L | 3 |
| Anderson, H | 1 |
| Prósper, F | 1 |
| Paloma, MJ | 1 |
| Rifón, J | 1 |
| Cuesta, B | 1 |
| Hermida, J | 1 |
| Rocha, E | 1 |
| Tura, S | 1 |
| Stellink, F | 1 |
| Geurts van Kessel, A | 1 |
| Nand, S | 1 |
| Stock, W | 1 |
| Godwin, J | 1 |
| Fisher, SG | 1 |
| Mital, A | 1 |
| Czyz, J | 1 |
| Hellmann, A | 1 |
| Tesselaar, ME | 1 |
| Wijermans, PW | 1 |
| Metsaars, JA | 1 |
| Gerrits, WB | 1 |
| Haak, HL | 1 |
| van Genderen, PJ | 1 |
| Lindemans, J | 1 |
| van Vliet, HH | 1 |
| Barbone, E | 1 |
| Zerbinati, P | 1 |
| Soini, B | 1 |
| Rossi, C | 1 |
| Sánchez Fayos, J | 1 |
| Román Barbero, A | 1 |
| Nevado Reviriego, I | 1 |
| Salmon-Ehr, V | 1 |
| Grosieux, C | 1 |
| Potron, G | 1 |
| Kalis, B | 1 |
| Heis, N | 1 |
| Rintelen, C | 1 |
| Gisslinger, B | 1 |
| Knöbl, P | 1 |
| Lechner, K | 1 |
| Gisslinger, H | 1 |
| Samuelsson, J | 1 |
| Higuchi, T | 1 |
| Oba, R | 1 |
| Endo, M | 1 |
| Harada, H | 1 |
| Mori, H | 1 |
| Niikura, H | 1 |
| Omine, M | 1 |
| Fujita, K | 1 |
| Kreft, A | 1 |
| Nolde, C | 1 |
| Büsche, G | 1 |
| Buhr, T | 1 |
| Kreipe, H | 1 |
| Georgii, A | 1 |
| Andréasson, B | 1 |
| Carneskog, J | 1 |
| Lindstedt, G | 1 |
| Lundberg, PA | 1 |
| Swolin, B | 1 |
| Wadenvik, H | 1 |
| Kutti, J | 2 |
| Bennett, M | 1 |
| Grunwald, AJ | 1 |
| Solberg, LA | 1 |
| Rachmilewitz, B | 1 |
| Manny, N | 1 |
| Rachmilewitz, M | 1 |
| Dittmar, K | 1 |
| MacDougall, BK | 1 |
| Weinerman, BH | 1 |
| Kemel, S | 1 |
| Pettit, JE | 1 |
| Lewis, SM | 2 |
| Nicholas, AW | 1 |
| Semeraro, N | 1 |
| Cortellazzo, S | 1 |
| Colucci, M | 1 |
| Mathé, G | 1 |
| Osechenskaia, GV | 1 |
| Krasiukova, LI | 1 |
| Corneo, G | 1 |
| Galli, C | 1 |
| Airoldi, M | 1 |
| Ceccherini Nelli, L | 1 |
| Hussain, S | 1 |
| Walden, R | 1 |
| Adar, R | 1 |
| Mozes, M | 1 |
| Demidova, AV | 1 |
| Siver, AP | 1 |
| Pogorzhel'skiĭ, VI | 1 |
| Staven, P | 1 |
| VAN DER Hagen, CB | 1 |
| Vogt, E | 1 |
| Sandnes, K | 1 |
| Maurice, P | 1 |
| Miller, JB | 1 |
| Pezzimenti, JF | 1 |
| Kim, HC | 1 |
| Lindenbaum, J | 1 |
| Lennert, K | 1 |
| Nagai, K | 1 |
| Schwarze, EW | 1 |
| Loeb, V | 1 |
| Hino, K | 1 |
| Sato, S | 1 |
| Sakashita, A | 1 |
| Tomoyasu, S | 1 |
| Tsuruoka, N | 1 |
| Koike, T | 1 |
| Grossi, A | 1 |
| Vannucchi, AM | 1 |
| Longo, G | 1 |
| Rafanelli, D | 1 |
| Rossi Ferrini, P | 1 |
| Scheffer, MG | 1 |
| Simoons, ML | 1 |
| Roelandt, JR | 1 |
| Wehmeier, A | 1 |
| Daum, I | 1 |
| Jamin, H | 1 |
| Schneider, W | 1 |
| Kimura, S | 1 |
| Uoshima, N | 1 |
| Tanaka, R | 1 |
| Kobayashi, Y | 2 |
| Ozawa, M | 1 |
| Maruo, N | 1 |
| Kondo, M | 1 |
| Abe, T | 1 |
| Yoshida, Y | 1 |
| Masaoka, T | 1 |
| Fischer, H | 1 |
| Avissar, N | 1 |
| Farkash, Y | 1 |
| Pagano, L | 1 |
| Teofili, L | 1 |
| Marra, R | 1 |
| Storti, S | 1 |
| Rabbitti, C | 1 |
| Leone, G | 1 |
| Bizzi, B | 1 |
| Burger, T | 1 |
| Schmelczer, M | 1 |
| Molnár, L | 1 |
| Pajor, L | 1 |
| Koszorús, S | 1 |
| Zittoun, R | 1 |
| Kovaleva, LG | 1 |
| Kho, PI | 1 |
| Messinezy, M | 1 |
| Pearson, TC | 1 |
| Prochazka, A | 1 |
| Wetherley-Mein, G | 1 |
| Paladini, G | 1 |
| Tosato, F | 1 |
| Mazzanti, G | 1 |
| Covaz, E | 1 |
| d'Auteuil, P | 1 |
| Urasiński, I | 3 |
| Mysik, M | 2 |
| Honetz, N | 1 |
| Klotz, H | 1 |
| Neumann, E | 1 |
| Vivacqua, RJ | 1 |
| Haurani, FI | 1 |
| Erslev, AJ | 1 |
| Helbig, W | 1 |
| Schwenke, H | 1 |
| Müldner, J | 1 |
| Gahrton, G | 2 |
| Franzén, S | 2 |
| Nordén, A | 1 |
| Bernadou, A | 1 |
| Clauvel, JP | 1 |
| Antebi, L | 1 |
| Bilski-Pasquier, G | 1 |
| Hennemann, HH | 2 |
| Stecher, G | 3 |
| Szur, L | 1 |
| Rorvik, TO | 1 |
| Rudowski, W | 1 |
| Klawe, Z | 1 |
| Woźniewska, M | 1 |
| Ziemski, JM | 1 |
| Cardamone, JM | 1 |
| Edson, JR | 1 |
| McArthur, JR | 1 |
| Jacob, HS | 1 |
| Comhaire, F | 1 |
| Van Hove, W | 1 |
| Van Ganse, W | 1 |
| Van der Straeten, M | 1 |
| Inceman, S | 1 |
| Tangün, Y | 1 |
| Zetterberg, A | 1 |
| Baikie, AG | 1 |
| Jamshidi, K | 1 |
| Ansari, A | 1 |
| Windschitl, HE | 1 |
| Swaim, WR | 1 |
| Dyk, T | 1 |
| Piotrowski, M | 1 |
| Kostecka, W | 1 |
| Szczepkowska, W | 1 |
| Waldenström, JG | 1 |
| Visfeldt, J | 1 |
| Nielsen, A | 1 |
| Tribukait, B | 1 |
| Martinez, J | 1 |
| Shapiro, SS | 1 |
| Holburn, RR | 1 |
| McGrath, CJ | 1 |
| Kurita, S | 1 |
| Ward, HP | 1 |
| Block, MH | 1 |
| Wasserman, LR | 1 |
| Alberto, P | 1 |
| Czerniak, P | 1 |
| Zari, A | 1 |
| Ernst, P | 1 |
| Boye Nielsen, J | 1 |
| Killman, SE | 1 |
| Pegrum, GD | 1 |
| Sellei, C | 1 |
| Reinhardt, G | 1 |
| Israëls, MC | 2 |
| Donaldson, GW | 1 |
| McArthur, M | 1 |
| Macpherson, AI | 1 |
| Richmond, J | 1 |
| Robertson, JH | 1 |
| Littler, WA | 1 |
| Ogilvie, C | 1 |
| Kajiwara, N | 1 |
| Kanmatsuse, K | 1 |
| Koshino, M | 1 |
| Sato, M | 1 |
| Ianovskiĭ, DN | 1 |
| Chepeleva, MA | 1 |
| Binder, RA | 1 |
| Gilbert, HS | 1 |
| Baxter, MF | 1 |
| Reinfrank, RF | 1 |
| Yde, H | 1 |
| Siguier, F | 1 |
| Godeau, P | 1 |
| Delluc, G | 1 |
| Sraer, JD | 1 |
| Jamra, M | 1 |
| Verrastro, T | 1 |
| Kahn, SB | 1 |
| Brady, LW | 1 |
| Millard, RE | 1 |
| Lawler, SD | 1 |
| Kay, HE | 1 |
| Cameron, CB | 1 |
| Penttilä, O | 1 |
| Ikkala, E | 1 |
| Vodopick, H | 1 |
| Hamilton, HE | 1 |
| Jackson, HL | 1 |
| Peng, CT | 1 |
| Sheets, RF | 1 |
| Vallée, G | 1 |
| Boivin, P | 1 |
| Dormont, J | 1 |
| Soulier, JP | 1 |
| Reed, C | 1 |
| Krykowski, E | 1 |
| Wislawska, B | 1 |
| Polkowska-Kulesza, E | 1 |
| Epstein, IS | 1 |
| Migdal, A | 1 |
| Kratochvil, J | 1 |
| Mrkos, D | 1 |
| Szentkláray, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Benefit/Risk Profile of Pegylated Proline-Interferon Alpha-2b (AOP2014) Added to the Best Available Strategy Based on Phlebotomies in Low-risk Patients With Polycythemia Vera (PV). The Low-PV Randomized Trial[NCT03003325] | Phase 2 | 127 participants (Actual) | Interventional | 2017-02-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for busulfan and Polycythemia Vera
| Article | Year |
|---|---|
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Topics: Busulfan; Female; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Leukocytosis; Male; Microcircula | 2023 |
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
Topics: Age Factors; Aspirin; Busulfan; Calreticulin; Disease-Free Survival; Humans; Interferon-alpha; Janus | 2020 |
Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea.
Topics: Antineoplastic Agents; Busulfan; Disease Management; Drug Resistance; Histone Deacetylase Inhibitors | 2014 |
Where to Turn for Second-Line Cytoreduction After Hydroxyurea in Polycythemia Vera?
Topics: Busulfan; Cell Proliferation; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myeloid, Acute; Nitrile | 2016 |
Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management.
Topics: Acute Disease; Age Factors; Alkylating Agents; Anticoagulants; Aspirin; Busulfan; Disease Management | 2012 |
Busulphan treatment of polycythaemia vera.
Topics: Busulfan; Chlorambucil; Clinical Trials as Topic; Humans; Leukemia; Polycythemia Vera | 1982 |
[Association of polycythemia vera and multiple myeloma. Presentation ofa new case and review of the literature].
Topics: Aged; Bloodletting; Busulfan; Combined Modality Therapy; Humans; Male; Multiple Myeloma; Phosphorus | 1993 |
The management of elderly patients with myeloproliferative disorders.
Topics: Adult; Age Factors; Aged; Bone Marrow Transplantation; Busulfan; Chronic Disease; Humans; Hydroxyure | 1993 |
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage; | 1996 |
[Efficacious treatment of a fatal blood disease: polycythemia vera].
Topics: Acute Disease; Alkylating Agents; Busulfan; Chlorambucil; Humans; Hydroxyurea; Leukemia, Myeloid; Le | 1997 |
Transition of polycythemia vera to chronic neutrophilic leukemia.
Topics: Busulfan; Humans; Hydroxyurea; Leukemia, Neutrophilic, Chronic; Male; Middle Aged; Polycythemia Vera | 1999 |
Therapeutic options for essential thrombocythemia and polycythemia vera.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Busulfan; Fibrinolytic Agen | 2002 |
Disorders of hemostasis and thrombosis in the aged.
Topics: Adolescent; Adult; Aged; Aortic Aneurysm; Blood Coagulation Disorders; Blood Coagulation Factors; Bl | 1976 |
Patho-anatomical features of the bone marrow.
Topics: Bone Marrow; Busulfan; Diagnosis, Differential; Erythropoiesis; Granulocytes; Humans; Leukemia, Myel | 1975 |
Treatment of polycythaemia vera.
Topics: Bloodletting; Busulfan; Chlorambucil; Cyclophosphamide; Humans; Injections, Intravenous; Internation | 1975 |
[Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report].
Topics: Blast Crisis; Busulfan; Carbazilquinone; Disseminated Intravascular Coagulation; Humans; Leukemia, M | 1992 |
[Essential thrombocythemia: conventional therapy].
Topics: Adult; Antineoplastic Agents; Busulfan; Follow-Up Studies; Hemorrhage; Humans; Hydroxyurea; Immunolo | 1991 |
[Onset of polycythemia in idiopathic myelofibrosis. Description of a clinical case and review of the literature].
Topics: Adrenal Cortex Hormones; Anemia; Biopsy; Bone Marrow; Busulfan; Female; Humans; Liver; Middle Aged; | 1988 |
The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome.
Topics: Adrenal Cortex Hormones; Alkaline Phosphatase; Androgens; Anemia; Animals; Blood Cell Count; Blood C | 1971 |
The management of polycythaemia vera.
Topics: Acute Disease; Alkylating Agents; Bloodletting; Bone Marrow Diseases; Busulfan; Humans; Leukemia; Ph | 1971 |
8 trials available for busulfan and Polycythemia Vera
| Article | Year |
|---|---|
Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Blood Cell Count; Busulfan; Comorbidity; Disease Progres | 2014 |
Allogeneic hematopoietic stem cell transplantation for myelofibrosis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; C | 2003 |
Treatment of polycythaemia vera by radiophosphorus or busulphan: a randomized trial. "Leukemia and Hematosarcoma" Cooperative Group, European Organization for Research on Treatment of Cancer (E.O.R.T.C.).
Topics: Aged; Bloodletting; Busulfan; Clinical Trials as Topic; Female; Humans; Male; Phosphorus Radioisotop | 1981 |
Busulphan treatment of polycythaemia vera.
Topics: Busulfan; Chlorambucil; Clinical Trials as Topic; Humans; Leukemia; Polycythemia Vera | 1982 |
[Evaluation of treatment results in patients with polycythemia rubra vera].
Topics: Adult; Aged; Aged, 80 and over; Busulfan; Female; Humans; Leukocyte Count; Male; Middle Aged; Platel | 1996 |
Treatment by radiophosphorus versus busulfan in polycythemia vera: a randomized trial (E.O.R.T.C.'s) "leukemias and hematosarcomas" group.
Topics: Busulfan; Clinical Trials as Topic; Female; Humans; Leukemia; Male; Middle Aged; Phosphorus Radioiso | 1977 |
[Ranimustine].
Topics: Antineoplastic Agents; Busulfan; Drug Evaluation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Po | 1990 |
Busulfan versus 32P in polycythaemia vera.
Topics: Aged; Busulfan; Clinical Trials as Topic; Humans; Middle Aged; Phosphorus Radioisotopes; Polycythemi | 1986 |
132 other studies available for busulfan and Polycythemia Vera
| Article | Year |
|---|---|
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans; | 2019 |
JAK2V617F allele burden is reduced by busulfan therapy: a new observation using an old drug.
Topics: Aged; Aged, 80 and over; Alleles; Busulfan; Female; Humans; Janus Kinase 2; Male; Myeloablative Agon | 2013 |
Effect of busulfan on JAK2V617F allele burden.
Topics: Alleles; Busulfan; Female; Humans; Janus Kinase 2; Male; Myeloablative Agonists; Polycythemia Vera | 2014 |
Effect of conditioning regimens on graft failure in myelofibrosis: a retrospective analysis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Calreticulin; Com | 2015 |
Busulfan for the treatment of myeloproliferative neoplasms: the Mayo Clinic experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Female; Humans; Male; M | 2016 |
Megakaryoblastic transformation of polycythemia vera with hypercalcemia.
Topics: Adrenocorticotropic Hormone; Bone Resorption; Busulfan; Calcium; Cell Transformation, Neoplastic; Di | 2002 |
Aspirin-responsive painful red, blue, black toe, or finger syndrome in polycythemia vera associated with thrombocythemia.
Topics: Aged; Aspirin; Busulfan; Erythromelalgia; Female; Fingers; Hematocrit; Humans; Male; Middle Aged; Pl | 2003 |
Therapy of polycythemia vera with myleran.
Topics: Busulfan; Humans; Polycythemia Vera | 1958 |
Treatment of polycythemia vera with busulfan (myleran).
Topics: Busulfan; Humans; Polycythemia Vera | 1958 |
[Treatment of polycythemia vera with 1, 4-dimethylsulfonoxybutane].
Topics: Busulfan; Humans; Polycythemia Vera | 1959 |
[Fatal pancytopenia after treatment of polycythemia vera with myleran].
Topics: Anemia; Anemia, Aplastic; Busulfan; Humans; Pancytopenia; Polycythemia Vera; Tracheophyta | 1960 |
Treatment of polycythemia vera with myleran.
Topics: Busulfan; Humans; Polycythemia Vera | 1961 |
[Myleran therapy of erythrocythemia vera].
Topics: Busulfan; Humans; Polycythemia; Polycythemia Vera | 1961 |
[Successful ambulant treatment of a case of polycythemia with Myeleukon].
Topics: Busulfan; Humans; Polycythemia; Polycythemia Vera | 1962 |
Polycythemia.
Topics: Aged; Busulfan; Humans; Phosphorus Isotopes; Polycythemia; Polycythemia Vera | 1962 |
[Prolonged use of Mablin powder in a case of polycythemia vera].
Topics: Busulfan; Humans; Polycythemia Vera; Powders | 1962 |
[Further observations on the therapeutic effect of Myleran in polycythemia vera].
Topics: Busulfan; Humans; Polycythemia Vera | 1963 |
[THE ROLE OF THE PLASMA FACTOR IN LEUKOCYTOPOIESIS].
Topics: Agranulocytosis; Busulfan; Hematopoiesis; Hypersplenism; Leukemia; Leukemia, Lymphoid; Leukemoid Rea | 1963 |
[THE BLOOD VOLUME IN POLYCYTHEMIA VERA AND ITS CHANGE DURING THERAPY. A CLINICAL CONTRIBUTION TO THE PROBLEM OF BLOOD VOLUME REGULATION].
Topics: Blood Volume; Busulfan; Hematocrit; Hemoglobinometry; Humans; Phosphorus Isotopes; Polycythemia Vera | 1963 |
IN-VITRO SENSITIVITY TESTS OF LEUKAEMIC CELLS TO CHEMOTHERAPEUTIC AGENTS.
Topics: Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Geriatrics; H | 1964 |
[POLYCYTHEMIA].
Topics: Busulfan; Diagnosis, Differential; Heparin; Humans; Phosphorus Isotopes; Physiology; Polycythemia; P | 1964 |
THE USE OF FERROKINETICS IN THE EVALUATION OF BUSULPHAN THERAPY IN POLYCYTHAEMIA VERA.
Topics: Bloodletting; Bone Marrow; Busulfan; Drug Therapy; Erythropoiesis; Geriatrics; Hematology; Hemoglobi | 1964 |
[HEMORRHAGIC THROMBOCYTHEMIA AND THE "MYELOPROLIFERATIVE SYNDROME"].
Topics: Anemia; Anemia, Hypochromic; Blood Platelets; Busulfan; Gastrointestinal Hemorrhage; Hemorrhage; Hem | 1964 |
[TREATMENT OF ERYTHREMIA WITH MYELOSAN].
Topics: Blood Platelets; Busulfan; Drug Therapy; Erythrocyte Count; Hemoglobinometry; Humans; Leukocyte Coun | 1964 |
[Study with the aid of Fe-59, of the erythrokinetics of the essential polyglobulias and of their modifications using myleran].
Topics: Busulfan; Erythrocytes; Humans; Iron; Polycythemia Vera | 1961 |
Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera.
Topics: Aged; Anti-Bacterial Agents; Busulfan; Combined Modality Therapy; Debridement; Female; Heparin; Hern | 2003 |
[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; | 2004 |
Safety profile of hydroxyurea in the treatment of patients with Philadelphia-negative chronic myeloproliferative disorders.
Topics: Adult; Aged; Aged, 80 and over; Busulfan; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Leukemia, | 2005 |
Alteration of platelets and virus-like particles by busulfan in myeloproliferative disorders.
Topics: Blood Platelets; Busulfan; Humans; Leukemia, Myeloid; Myeloproliferative Disorders; Polycythemia Ver | 1980 |
Busulphan: effect on platelet RNA dependent DNA polymerase--implications in the treatment of polycythemia vera, thrombosis and atherosclerosis.
Topics: Arteriosclerosis; Blood Platelets; Busulfan; Humans; Polycythemia Vera; RNA-Directed DNA Polymerase; | 1982 |
Redistribution of granulopoiesis from extramedullary territories to bone marrow in a case of spent polycythemia treated with alkylating agents.
Topics: Biopsy; Blood Cell Count; Bone Marrow; Busulfan; Chlorambucil; Female; Granulocytes; Humans; Karyoty | 1984 |
[Polycythemia vera complicated by choreoathetosis].
Topics: Athetosis; Bloodletting; Busulfan; Chorea; Female; Humans; Middle Aged; Polycythemia Vera | 1984 |
Transformation of erythrocytosis associated with renal cyst to polycythemia vera.
Topics: Aged; Busulfan; Humans; Kidney Diseases, Cystic; Male; Polycythemia; Polycythemia Vera | 1980 |
Conservative treatment of Budd-Chiari syndrome in polycythemia vera.
Topics: Aspirin; Budd-Chiari Syndrome; Busulfan; Dipyridamole; Female; Furosemide; Humans; Leukapheresis; Mi | 1981 |
Myelosuppression in polycythemia vera: chemotherapy or radiotherapy?
Topics: Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Humans; Melphalan; Phosphorus Radioisotopes; | 1982 |
Polycythemia Vera.
Topics: Aged; Busulfan; Female; Humans; Hypercalcemia; Hyperparathyroidism; Polycythemia Vera | 1982 |
Survival and risk of leukaemia in polycythaemia vera and essential thrombocythaemia treated with oral radiophosphorus: are safer drugs available?
Topics: Administration, Oral; Aged; Busulfan; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukemi | 1995 |
Derivative (y)t(Y;1)(q12;q12),+9 in a patient with polycythemia vera during transition into myelodysplasia.
Topics: Bone Marrow; Busulfan; Chromosome Aberrations; Chromosomes, Human, Pair 1; Humans; In Situ Hybridiza | 1996 |
Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Busulfan; Cell Transformation, Neoplastic; | 1996 |
[Radioactive phosphorus (32P); an old but not bad treatment for polycythemia vera].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Female; Humans; Leukemi | 1996 |
Essential thrombocythemia following polycythemia vera: an unusual sequence.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Busulfan; Hematocrit; Humans; Leukocyte Count; Male; Pho | 1996 |
Busulfan versus hydroxyurea in the treatment of polycythemia vera (PV) and essential thrombocythemia (ET)
Topics: Antineoplastic Agents; Busulfan; Humans; Hydroxyurea; Immunosuppressive Agents; Polycythemia Vera; R | 1998 |
Multiple actinic keratosis and skin tumors secondary to hydroxyurea treatment.
Topics: Aged; Antineoplastic Agents; Busulfan; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Hydr | 1998 |
Is hydroxyurea leukemogenic in essential thrombocythemia?
Topics: Acute Disease; Antineoplastic Agents, Alkylating; Bone Marrow; Busulfan; Chromosome Aberrations; Chr | 1998 |
The effect of interferon alpha on myeloproliferation and vascular complications in polycythemia vera.
Topics: Adult; Aged; Aged, 80 and over; Busulfan; Drug Tolerance; Erysipelas; Erythropoiesis; Female; Hemato | 1999 |
Survival in a patient with polycythaemia vera for over thirty years: implications for treatment decisions in younger patients.
Topics: Adult; Busulfan; Female; Humans; Hydroxyurea; Phlebotomy; Phosphorus Radioisotopes; Polycythemia Ver | 1998 |
Polycythaemia vera: bone marrow histopathology under treatment with interferon, hydroxyurea and busulphan.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Bone Marrow; Busulfan; Follow-Up Studies; Hematopoietic Stem | 2000 |
Plasma erythropoietin concentrations in polycythaemia vera with special reference to myelosuppressive therapy.
Topics: Adult; Aged; Busulfan; Erythropoietin; Female; Humans; Hydroxyurea; Immunosuppressive Agents; Interf | 2000 |
Hydroxyurea and periodicity in myeloproliferative disease.
Topics: Adult; Aged; Antineoplastic Agents; Blood Cell Count; Busulfan; Female; Hemoglobins; Humans; Hydroxy | 2001 |
Effect of busulfan on oncornavirus-like activity in platelets and chromosomes in polycythemia vera and essential thrombocythemia.
Topics: Aged; Aneuploidy; Blood Cell Count; Blood Platelets; Busulfan; Chromosomes; Female; Humans; Oncogeni | 1977 |
The transcobalamins in polycythaemia vera.
Topics: Blood Proteins; Busulfan; Humans; Leukemia, Myeloid, Acute; Melphalan; Polycythemia Vera; Protein Bi | 1977 |
Acute myeloblastic leukemia with polycythemia vera. Treated with busulfan and phlebotomy.
Topics: Bloodletting; Busulfan; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Middle Ag | 1979 |
Treatment of polycythemia vera.
Topics: Acute Disease; Adult; Aged; Bloodletting; Busulfan; Evaluation Studies as Topic; Female; Humans; Leu | 1979 |
Transitional myeloproliferative disorder.
Topics: Adult; Aged; Blood Cell Count; Busulfan; Female; Folic Acid; Follow-Up Studies; Humans; Iron; Male; | 1979 |
A hitherto undescribed defect of platelet coagulant activity in polycythaemia vera and essential thrombocythaemia.
Topics: Adult; Aged; Blood Coagulation; Blood Platelets; Busulfan; Factor V; Factor X; Female; Humans; Male; | 1979 |
Survival of patients with polycythemia vera on busulfan or 32P.
Topics: Busulfan; Humans; Phosphorus Radioisotopes; Polycythemia Vera | 1978 |
[Current aspects of the treatment of polycythemia vera under polyclinical conditions].
Topics: Ambulatory Care; Antineoplastic Agents; Aziridines; Bloodletting; Busulfan; Drug Evaluation; Humans; | 1978 |
[Clinical and therapeutic aspects of polycythemia vera].
Topics: Adult; Age Factors; Aged; Bilirubin; Blood Cell Count; Blood Urea Nitrogen; Bloodletting; Busulfan; | 1978 |
Gangrene of toes with normal peripheral pulses.
Topics: Adult; Aged; Amputation, Surgical; Arteriosclerosis; Busulfan; Collateral Circulation; Diabetic Angi | 1977 |
[Case of myelosan-induced hematopoietic aplasia in erythremia].
Topics: Aged; Bone Marrow Diseases; Busulfan; Female; Humans; Polycythemia Vera | 1977 |
Polycythemia vera treated with -32p and myleran: development of chronic granulocytic leukemia with chromosomal abnormalities in one patient.
Topics: Anemia, Hemolytic, Autoimmune; Busulfan; Chromosomes, Human, 1-3; Chromosomes, Human, 6-12 and X; Ch | 1975 |
[The treatment of myeloproliferative syndromes].
Topics: Aged; Bloodletting; Busulfan; Chlorambucil; Female; Humans; Leukemia, Myeloid; Male; Myeloproliferat | 1975 |
Chronic myelocytic leukemia and the myeloproliferative diseases during the child-bearing years.
Topics: Aged; Busulfan; Child; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Myeloproliferative Diso | 1976 |
Erythroleukemia-like syndrome due to busulfan toxicity in polycythemia vera.
Topics: Adult; Bone Marrow; Bone Marrow Diseases; Busulfan; Female; Humans; Leukemia, Erythroblastic, Acute; | 1976 |
Thrombocythemia and coronary artery disease.
Topics: Adult; Aged; Aspirin; Busulfan; Coronary Disease; Female; Humans; Male; Middle Aged; Polycythemia Ve | 1991 |
Incidence and clinical risk factors for bleeding and thrombotic complications in myeloproliferative disorders. A retrospective analysis of 260 patients.
Topics: Bloodletting; Busulfan; Cause of Death; Hemorrhage; Humans; Incidence; Leukemia, Myelogenous, Chroni | 1991 |
[Polycythemia vera terminating in myelodysplastic syndrome].
Topics: Aged; Busulfan; Carbazilquinone; Humans; Male; Myelodysplastic Syndromes; Polycythemia Vera | 1990 |
[Leukergy-stimulating factors in polycythemia vera].
Topics: Adult; Busulfan; Cell Aggregation; Female; Humans; Leukocytes; Lymphocyte Activation; Lymphokines; M | 1985 |
Erythrocyte enzymes in polycythemia vera: a comparison to erythrocyte enzyme activities of patients with iron deficiency anemia.
Topics: Anemia, Hypochromic; Bloodletting; Busulfan; Combined Modality Therapy; Cytoplasm; Erythrocyte Aging | 1986 |
[Clinical course and transformation of polycythemia vera and its relation to applied therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Chlorambucil; Combined Modali | 1987 |
[Effectiveness of cytostatic therapy of polycythemia vera].
Topics: Adult; Aged; Antineoplastic Agents; Aziridines; Busulfan; Humans; Middle Aged; Mitobronitol; Phospho | 1986 |
Treatment of primary proliferative polycythaemia by venesection and low dose busulphan: retrospective study from one centre.
Topics: Adult; Aged; Bloodletting; Busulfan; Female; Humans; Male; Middle Aged; Polycythemia Vera; Primary M | 1985 |
[Development of polycythemia vera during chronic idiopathic myelofibrosis].
Topics: Adult; Anemia, Myelophthisic; Busulfan; Chronic Disease; Hepatomegaly; Humans; Male; Platelet Count; | 1985 |
[Treatment of Vaquez' disease].
Topics: Bloodletting; Busulfan; Humans; Phosphorus Radioisotopes; Polycythemia Vera; Prognosis | 1985 |
[Therapy of polycythemia vera with busulfan (myleran). Report on results in 40 patients].
Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Bloodletting; Busulfan; Erythrocyte Count; Female; H | 1970 |
[Iron metabolism in polycythemia vera].
Topics: Aged; Antineoplastic Agents; Bloodletting; Busulfan; Deferoxamine; Female; Hematocrit; Humans; Intes | 1971 |
"Selective" pituitary insufficiency secondary to busulfan.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged | 1967 |
[Cytostatic therapy of chronic myelosis and polycythemia vera with myelobromol (dibrommannitol)].
Topics: Alkaline Phosphatase; Alkylating Agents; Blood Platelets; Busulfan; Hematocrit; Hemoglobinometry; Hu | 1969 |
Cytochemical variants of neutrophil leukocyte populations in chronic myelocytic leukaemia. A microspectrophotometric study of the change in the periodic acid-Schiff (PAS) reaction in blood and bone marrow neutrophils during busulfan treatment.
Topics: Bone Marrow; Bone Marrow Cells; Busulfan; Histocytochemistry; Humans; Leukemia, Myeloid; Neutrophils | 1969 |
[Vaquez's diseas. Clinical and developmental study. Apropos of 144 cases].
Topics: Adult; Arteriosclerosis; Arteritis; Blood Sedimentation; Busulfan; Child; Erythrocyte Count; Female; | 1968 |
[The therapy of polycythemia vera].
Topics: Alkylating Agents; Anticoagulants; Bloodletting; Busulfan; Chlorambucil; Histamine H1 Antagonists; H | 1967 |
Blood and neoplastic diseases. Myeloproliferative disorders.
Topics: Adrenal Cortex Hormones; Androgens; Blood Transfusion; Bloodletting; Busulfan; Chlorambucil; Cycloph | 1974 |
[Polycythemia vera].
Topics: Busulfan; Chronic Disease; Diagnosis, Differential; Hemorrhage; Humans; Phosphorus Radioisotopes; Po | 1974 |
Major surgery in patients with polycythaemia vera.
Topics: Aged; Blood Platelets; Blood Transfusion, Autologous; Bloodletting; Busulfan; Erythrocyte Count; Fem | 1974 |
Abnormalities of platelet function in the myeloproliferative disorders.
Topics: Acute Disease; Adult; Blood Coagulation Tests; Blood Platelet Disorders; Busulfan; Female; Humans; L | 1972 |
Busulphan and the lungs. Absence of lung function disturbance in patients treated with busulphan.
Topics: Adult; Aged; Busulfan; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Mi | 1972 |
Platelet defects in the myeloproliferative disorders.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Coagulation Tests; Blood Platelets; Busulfan; Densitometry | 1972 |
Cytochemical population analyses of glycogen in neutrophil leukocytes of chronic myelocytic leukaemia during busulfan treatment.
Topics: Adult; Aged; Busulfan; Glucose; Glycogen; Histocytochemistry; Humans; Leukemia, Myeloid; Middle Aged | 1972 |
Chronic granulocytic leukaemia.
Topics: Adult; Busulfan; Child; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chronic Disease; Di | 1974 |
Primary thrombocythemia.
Topics: Adult; Aged; Blood Coagulation Tests; Bone Marrow Examination; Busulfan; Follow-Up Studies; Gastroin | 1973 |
[Acute hemopericardium due to acute thrombocytopenia developing during Busulphan treatment of polycythemia vera].
Topics: Acute Disease; Adult; Anemia, Aplastic; Busulfan; Cardiac Tamponade; Humans; Male; Pericardial Effus | 1973 |
[Alkaline phosphatase activity in neutrophils in polycythemia vera and in secondary erythrocytosis].
Topics: Adult; Aged; Alkaline Phosphatase; Busulfan; Diagnosis, Differential; Female; Humans; Male; Middle A | 1973 |
From bad to worse? Treatment and leukemogenesis.
Topics: Antibiotics, Antineoplastic; Busulfan; Chlorambucil; Chromosome Aberrations; Chromosome Disorders; H | 1973 |
Primary polycythaemia. 3. Studies on the significance of the history of the disease and of the treatment for the development of clones in bone marrow cells.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Busulfan; Cell Transformation, Neoplastic; Clone Cells; | 1973 |
Metabolism of human prothrombin and fibrinogen in patients with thrombocytosis secondary to myeloproliferative states.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Blood Cell Count; Blood Coagulation Factors; Blood Co | 1973 |
Polycythemia vera in dogs.
Topics: Animals; Blood Proteins; Blood Volume; Bloodletting; Busulfan; Chromium Radioisotopes; Dog Diseases; | 1974 |
[Treatment and prognosis of polycythema vera in Japan (author's transl)].
Topics: Busulfan; Female; Humans; Japan; Male; Middle Aged; Phosphorus Radioisotopes; Polycythemia Vera; Pro | 1974 |
[Results of long-term treatment of polycythemia vera with busulfan (Myleran) or dibromomannitol (Myelobromol): analysis of 4 clinical cases observed and treated during more than 7 years].
Topics: Aged; Antineoplastic Agents; Busulfan; Female; Follow-Up Studies; Humans; Leukopenia; Long-Term Care | 1969 |
Platelet production rate in polycythemia vera after myelosuppressive therapy.
Topics: Aged; Blood Cell Count; Blood Platelets; Busulfan; Cell Division; Cell Survival; Chlorambucil; Chrom | 1972 |
[Combined chemo-radionuclide therapy of cancer (complexotherapy)].
Topics: Antineoplastic Agents; Busulfan; Female; Gold Isotopes; Humans; Male; Middle Aged; Ovarian Neoplasms | 1971 |
[Treatment of polycythemia vera].
Topics: Anemia, Aplastic; Busulfan; Humans; Leukopenia; Male; Middle Aged; Polycythemia Vera; Thrombocytopen | 1971 |
Stimulation in vitro of cells from patients with myeloproliferative disorders.
Topics: Autoradiography; Bone Marrow Diseases; Busulfan; Culture Techniques; Humans; Lectins; Leukemia, Myel | 1967 |
Treatment of myeloproliferative diseases.
Topics: Busulfan; Humans; Leukemia, Myeloid; Mannitol; Myeloproliferative Disorders; Polycythemia Vera; Prim | 1966 |
Chemotherapy in polycythemia vera.
Topics: Busulfan; Humans; Leukemia; Leukemia, Myeloid; Phosphorus Isotopes; Polycythemia Vera; Primary Myelo | 1968 |
Studies on the phagocytic activity of neutrophilic leukocytes.
Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Anemia, Macrocytic; Animals; Biopsy; Bone Marrow Dis | 1967 |
Management and therapy of polycythaemia vera.
Topics: Adolescent; Blood Cell Count; Bloodletting; Busulfan; Humans; Leukemia, Myeloid, Acute; Middle Aged; | 1969 |
Blood volume changes in splenomegaly.
Topics: Adolescent; Adult; Aged; Anemia; Blood Volume; Busulfan; Chromium Isotopes; Female; Hematocrit; Huma | 1970 |
Uracil mustard in the treatment of thrombocythemia.
Topics: Blood Cell Count; Blood Platelets; Bone Marrow Examination; Busulfan; Coronary Disease; Electrocardi | 1970 |
Lung function in patients receiving busulphan.
Topics: Adolescent; Adult; Aged; Blood Platelet Disorders; Busulfan; Female; Humans; Leukemia, Myeloid; Male | 1970 |
Pipobroman (Vercyte) - a new antineoplastic drug.
Topics: Anemia, Hemolytic; Antineoplastic Agents; Bone Marrow; Busulfan; Chlorambucil; Gastrointestinal Hemo | 1967 |
[Therapy of polycythemia vera].
Topics: Antimetabolites; Antineoplastic Agents; Bloodletting; Busulfan; Chlorambucil; Cyclophosphamide; Huma | 1969 |
[Case of polycythemia vera remitting with administration of Myleran].
Topics: Busulfan; Electrocardiography; Female; Humans; Middle Aged; Polycythemia Vera; Radiography, Thoracic | 1969 |
[Chemotherapy of patients with erythremia].
Topics: Adult; Aged; Bloodletting; Busulfan; Female; Humans; Male; Middle Aged; Polycythemia Vera | 1969 |
Muramidase in polycythemia vera.
Topics: Alkaline Phosphatase; Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukocyte Count; Muramidase; | 1970 |
Electrophoretic patterns of human leukocyte alkaline phosphatase in polycythemia vera.
Topics: Alkaline Phosphatase; Busulfan; Chlorambucil; Electrophoresis; Gels; Humans; Leukocytes; Phosphorus | 1971 |
[Myleran treatment in polycythemia vera].
Topics: Adult; Aged; Busulfan; Female; Hematocrit; Humans; Male; Middle Aged; Polycythemia Vera | 1971 |
[Budd-Chiari syndrome with polycythemia. Considerations on the pseudo-tumoral aspect].
Topics: Adult; Budd-Chiari Syndrome; Busulfan; Contraceptives, Oral; Diagnosis, Differential; Female; Humans | 1967 |
[Polycythemia vera: therapeutic use of busulfan. Comparison with radioactive phosphorous].
Topics: Adult; Busulfan; Female; Humans; Male; Middle Aged; Phosphorus Isotopes; Polycythemia Vera; Purpura, | 1967 |
Polycythaemia vera: differential diagnosis by ferrokinetic studies and treatment with busulphan (Myleran).
Topics: Blood Cell Count; Blood Platelets; Bone Marrow Examination; Busulfan; Diagnosis, Differential; Eryth | 1968 |
Further observations on patients with a chromosomal abnormality associated with polycythaemia vera.
Topics: Adult; Autoradiography; Blood Cell Count; Blood Group Antigens; Blood Platelets; Bone Marrow; Bone M | 1968 |
Procarbazine (Natulan) and busulfan in the treatment of polycythemia vera.
Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Female; Humans; Hydrazines; Leukopenia; Male; Middle A | 1968 |
Metabolic fate of tritiated busulfan in man.
Topics: Bone Marrow Diseases; Busulfan; Humans; Leukemia, Lymphoid; Lung Neoplasms; Metabolic Clearance Rate | 1969 |
[Present treatment of the Vaquez's disease].
Topics: Aged; Anemia; Anticoagulants; Antineoplastic Agents; Blood Donors; Blood Volume; Bloodletting; Busul | 1969 |
[Results of busulfan (myleran) therapy of polycythemia vera].
Topics: Adult; Aged; Busulfan; Female; Humans; Male; Middle Aged; Phosphorus Isotopes; Polycythemia Vera; Re | 1969 |
Polycythaemia rubra vera.
Topics: Busulfan; Female; Humans; Male; Middle Aged; Polycythemia Vera; Prognosis | 1965 |
[Therapy of polycythemia vera with myleran].
Topics: Adult; Aged; Busulfan; Female; Humans; Male; Middle Aged; Polycythemia Vera | 1965 |
The treatment of Polycythemia vera and thrombocythemia with myleran (busulphan).
Topics: Aged; Anemia; Busulfan; Female; Humans; Male; Phosphorus Isotopes; Polycythemia Vera; Thrombocythemi | 1965 |
Treatment of polycythaemia vera.
Topics: Busulfan; Humans; Leukemia, Radiation-Induced; Phosphorus Isotopes; Polycythemia Vera; Pyrimethamine | 1966 |
Treatment and prognosis of polycythaemia managed by non-radioactive methods.
Topics: Blood Platelets; Busulfan; Humans; Leukemia; Phosphorus Isotopes; Polycythemia Vera; Pyrimethamine | 1966 |
[A case of polycythemia vera treated with myleran].
Topics: Busulfan; Female; Humans; Middle Aged; Polycythemia Vera | 1966 |
[The treatment of polycythemia vera with busulfan].
Topics: Adult; Aged; Blood Cell Count; Busulfan; Female; Humans; In Vitro Techniques; Male; Middle Aged; Pol | 1966 |
[Treatment of polycythemia vera with Myelobromol].
Topics: Alkylating Agents; Busulfan; Humans; Middle Aged; Phosphorus Isotopes; Polycythemia Vera | 1966 |