busulfan has been researched along with Lysosomal Enzyme Disorders in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Median (range) oral clearance corrected for bioavailability (Cl/F in ml/min/kg), area under the curve (AUC in ng min/ml) and BU plasma concentration (Cp in ng/ml) with the fourth dose were 5." | 2.70 | Oral busulfan pharmacokinetics and engraftment in children with Hurler syndrome and other inherited metabolic storage diseases undergoing hematopoietic cell transplantation. ( Abel, S; DeFor, TE; Jacobson, P; Krivit, W; Park, JJ; Peters, C; Thrall, M, 2001) |
| " The busulfan clearance (assuming a bioavailability of 1) ranged from 2." | 1.29 | Busulfan disposition below the age of three: alteration in children with lysosomal storage disease. ( Boland, I; Challine, D; Fischer, A; Gluckman, E; Ledheist, F; Lemerle, S; Rahimy, C; Souillet, G; Vassal, G; Vilmer, E, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tokimasa, S | 1 |
| Ohta, H | 1 |
| Takizawa, S | 1 |
| Kusuki, S | 1 |
| Hashii, Y | 1 |
| Sakai, N | 1 |
| Taniike, M | 1 |
| Ozono, K | 1 |
| Hara, J | 1 |
| Vassal, G | 1 |
| Fischer, A | 1 |
| Challine, D | 1 |
| Boland, I | 1 |
| Ledheist, F | 1 |
| Lemerle, S | 1 |
| Vilmer, E | 1 |
| Rahimy, C | 1 |
| Souillet, G | 1 |
| Gluckman, E | 1 |
| Yeager, AM | 1 |
| Uhas, KA | 1 |
| Coles, CD | 1 |
| Davis, PC | 1 |
| Krause, WL | 1 |
| Moser, HW | 1 |
| Jacobson, P | 1 |
| Park, JJ | 1 |
| DeFor, TE | 1 |
| Thrall, M | 1 |
| Abel, S | 1 |
| Krivit, W | 1 |
| Peters, C | 1 |
1 trial available for busulfan and Lysosomal Enzyme Disorders
| Article | Year |
|---|---|
Oral busulfan pharmacokinetics and engraftment in children with Hurler syndrome and other inherited metabolic storage diseases undergoing hematopoietic cell transplantation.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Busulfan; Child; Child, Preschool; Combin | 2001 |
3 other studies available for busulfan and Lysosomal Enzyme Disorders
| Article | Year |
|---|---|
Umbilical cord-blood transplantations from unrelated donors in patients with inherited metabolic diseases: Single-institute experience.
Topics: Administration, Oral; Busulfan; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclophospha | 2008 |
Busulfan disposition below the age of three: alteration in children with lysosomal storage disease.
Topics: Age Factors; Biological Availability; Busulfan; Child, Preschool; Female; Humans; Infant; Lysosomal | 1993 |
Bone marrow transplantation for infantile ceramidase deficiency (Farber disease).
Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Developmental Disabilities; Female; Galacto | 2000 |