Page last updated: 2024-10-24

busulfan and Lung Diseases, Interstitial

busulfan has been researched along with Lung Diseases, Interstitial in 9 studies

Lung Diseases, Interstitial: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Research Excerpts

ExcerptRelevanceReference
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."6.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
" Graft-versus-host disease (GVHD) prophylaxis consisted of T-cell depletion with IgM monoclonal antibody T10B9 plus complement and posttransplant cyclosporine-A."3.69Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia. ( Baxter-Lowe, LA; Bunin, N; Camitta, B; Casper, J; Garbrecht, F; Hunter, J; Lawton, C; Murray, K; Pietryga, D; Truitt, R, 1995)
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."2.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
"We treated 51 patients with various hematological malignancies involving the bone marrow with busulfan (16 mg/kg) and cyclophosphamide (120 mg/kg) followed by reinfusion of autologous peripheral blood stem cells."2.68Phase I-II study of high-dose busulfan and cyclophosphamide followed by autologous peripheral blood stem cell transplantation for hematological malignancies: toxicities and hematopoietic recovery. ( Agaliotis, DP; Ballester, OF; Elfenbein, GJ; Fields, KK; Goldstein, SC; Hiemenz, JW; Janssen, WE; Perkins, JB; Zorksy, PE, 1996)
" Etoposide at a dose of 60-65 mg/kg in combination with TBI and cyclophosphamide was associated with a significantly increased incidence of life threatening or fatal toxicities compared with a combination using a dose of 25-50 mg/kg (15 of 24 vs."1.29Etoposide in combination with cyclophosphamide and total body irradiation or busulfan as conditioning for marrow transplantation in adults and children. ( Cahill, R; Deeg, HJ; Gadner, H; Ortlieb, M; Peters, C; Spitzer, TR; Tefft, MC; Torrisi, J; Urban, C, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's6 (66.67)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Scobioala, S1
Eich, HT1
OLINER, H1
SCHWARTZ, R1
RUBIO, F1
DAMESHEK, W1
Rodriguez, R1
Nademanee, A1
Ruel, N1
Smith, E1
Krishnan, A1
Popplewell, L1
Zain, J1
Patane, K1
Kogut, N1
Nakamura, R1
Sarkodee-Adoo, C1
Forman, SJ1
Casper, J1
Camitta, B1
Truitt, R1
Baxter-Lowe, LA1
Bunin, N1
Lawton, C1
Murray, K1
Hunter, J1
Pietryga, D1
Garbrecht, F1
Klingemann, HG1
Shepherd, JD1
Reece, DE1
Barnett, MJ1
Nantel, SH1
Sutherland, HJ1
Spinelli, JJ1
Phillips, GL1
Spitzer, TR1
Peters, C1
Ortlieb, M1
Tefft, MC1
Torrisi, J1
Cahill, R1
Gadner, H1
Urban, C1
Deeg, HJ1
Ballester, OF1
Agaliotis, DP1
Hiemenz, JW1
Janssen, WE1
Fields, KK1
Zorksy, PE1
Goldstein, SC1
Perkins, JB1
Elfenbein, GJ1
Ringdén, O1
Remberger, M1
Ruutu, T1
Nikoskelainen, J1
Volin, L1
Vindeløv, L1
Parkkali, T1
Lenhoff, S1
Sallerfors, B1
Mellander, L1
Ljungman, P1
Jacobsen, N1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Ibritumomab Tiuxetan (Zevalin®) in Association With a Fludarabine Based Reduced Conditioning Regimen and Allogenic Stem Cell Support in Chemo-sensitive Relapsed CD20 Positive Aggressive Non-Hodgkin's Lymphoma Patients.[NCT00607854]Phase 231 participants (Actual)Interventional2008-02-29Completed
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Chronic Phase CML[NCT00001144]Phase 250 participants Interventional1999-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for busulfan and Lung Diseases, Interstitial

ArticleYear
Risk stratification of pulmonary toxicities in the combination of whole lung irradiation and high-dose chemotherapy for Ewing sarcoma patients with lung metastases: a review.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Combined Modality Thera

2020
Regimen-related acute toxicities: pathophysiology, risk factors, clinical evaluation and preventive strategies.
    Bone marrow transplantation, 1994, Volume: 14 Suppl 4

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Tr

1994

Trials

2 trials available for busulfan and Lung Diseases, Interstitial

ArticleYear
Phase I-II study of high-dose busulfan and cyclophosphamide followed by autologous peripheral blood stem cell transplantation for hematological malignancies: toxicities and hematopoietic recovery.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Combined Modalit

1996
Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta
    Blood, 1999, Apr-01, Volume: 93, Issue:7

    Topics: Adolescent; Adult; Alopecia; Bone Marrow Transplantation; Bronchiolitis Obliterans; Busulfan; Catara

1999

Other Studies

5 other studies available for busulfan and Lung Diseases, Interstitial

ArticleYear
Interstitial pulmonary fibrosis following busulfan therapy.
    The American journal of medicine, 1961, Volume: 31

    Topics: Busulfan; Humans; Lung Diseases, Interstitial; Pulmonary Fibrosis

1961
Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Cause of Death; Cohort Studies; Cyclophosphamide; Disease-Free Su

2006
Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Actuarial Analysis; Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cycl

1995
Etoposide in combination with cyclophosphamide and total body irradiation or busulfan as conditioning for marrow transplantation in adults and children.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1994
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 25-1997. A 60-year-old man with pulmonary infiltrates after a bone marrow transplantation.
    The New England journal of medicine, 1997, Aug-14, Volume: 337, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Bone Marrow Transplantation; Busulfan; Cryptogenic Organi

1997