Page last updated: 2024-10-24

busulfan and Inflammation

busulfan has been researched along with Inflammation in 9 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to evaluate the toxicity and efficacy of high-dose busulfan, melphalan and thiotepa (Bu/Mel/TT) in patients with high-risk non-inflammatory breast cancer defined as stage II disease > or =10 lymph nodes (n = 52) or stage III (n = 69), and prognostic factors for treatment outcome."9.09High-dose busulfan, melphalan and thiotepa as consolidation for non-inflammatory high-risk breast cancer. ( Appelbaum, FR; Bensinger, W; Gutierrez-Delgado, F; Holmberg, LA; Hooper, H; Kawahara, K; Livingston, RB; Maziarz, RT; Montgomery, P; Rivkin, S; Weiden, P, 2000)
"The purpose of this study was to evaluate the toxicity and efficacy of high-dose busulfan, melphalan and thiotepa (Bu/Mel/TT) in patients with high-risk non-inflammatory breast cancer defined as stage II disease > or =10 lymph nodes (n = 52) or stage III (n = 69), and prognostic factors for treatment outcome."5.09High-dose busulfan, melphalan and thiotepa as consolidation for non-inflammatory high-risk breast cancer. ( Appelbaum, FR; Bensinger, W; Gutierrez-Delgado, F; Holmberg, LA; Hooper, H; Kawahara, K; Livingston, RB; Maziarz, RT; Montgomery, P; Rivkin, S; Weiden, P, 2000)
" Our aim was to compare non-myeloablative busulfan conditioning against head-shielded irradiation bone marrow chimeras prior to implantation of glioblastoma, a malignant brain tumour with a pro-inflammatory phenotype."3.91Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours. ( Bigger, BW; Forte, G; Kamaly-Asl, ID; Liao, A; O'Leary, C; Parker, H; Rowlston, S; Telfer, B; Williams, K; Youshani, AS, 2019)
"Exacerbation of infection during aplasia was observed in 3 patients; inflammatory flare at the infection site during neutrophil engraftment in 2: all 5 patients belonged to the subgroup of 9 with pre-existing infection."2.41Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000. ( Belohradsky, BH; Blanche, S; Bordigoni, P; Cant, A; Di Bartolomeo, P; Fischer, A; Flood, T; Gungor, T; Landais, P; Müller, S; Nagler, A; Ozsahin, H; Passwell, JH; Porta, F; Seger, RA; Slavin, S; Wulffraat, N; Zintl, F, 2002)
"Busulfan (BUS) is an anticancer agent with serious adverse effects on various body organs, including the lung and testis."1.91Sitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects. ( Abbas, MA; Ali, EA; Tayel, SG, 2023)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ali, EA1
Tayel, SG1
Abbas, MA1
Skurikhin, EG1
Pakhomova, AV1
Pershina, OV1
Ermolaeva, LA1
Krupin, VA1
Ermakova, NN1
Pan, ES1
Kudryashova, AI1
Rybalkina, OY1
Pavlovskaya, TB1
Litvyakov, NV1
Goldberg, VE1
Dygai, AM1
Youshani, AS1
Rowlston, S1
O'Leary, C1
Forte, G1
Parker, H1
Liao, A1
Telfer, B1
Williams, K1
Kamaly-Asl, ID1
Bigger, BW1
Qiao, J1
Huang, Y1
Xia, Y1
Chu, P1
Yao, H1
Xu, L1
Qi, K1
Liu, Y1
Xu, K1
Zeng, L1
Seger, RA1
Gungor, T1
Belohradsky, BH1
Blanche, S1
Bordigoni, P1
Di Bartolomeo, P1
Flood, T1
Landais, P1
Müller, S1
Ozsahin, H1
Passwell, JH1
Porta, F1
Slavin, S1
Wulffraat, N1
Zintl, F1
Nagler, A1
Cant, A1
Fischer, A1
WEBER, RE1
HELMAN, N1
Gutierrez-Delgado, F1
Holmberg, LA1
Hooper, H1
Appelbaum, FR1
Livingston, RB1
Maziarz, RT1
Weiden, P1
Rivkin, S1
Montgomery, P1
Kawahara, K1
Bensinger, W1
Dukes, M1
Chan, WC1
Willoughby, DA1

Reviews

1 review available for busulfan and Inflammation

ArticleYear
Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000.
    Blood, 2002, Dec-15, Volume: 100, Issue:13

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodie

2002

Trials

1 trial available for busulfan and Inflammation

ArticleYear
High-dose busulfan, melphalan and thiotepa as consolidation for non-inflammatory high-risk breast cancer.
    Bone marrow transplantation, 2000, Volume: 26, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Busulfan; Chemotherapy, Adj

2000

Other Studies

7 other studies available for busulfan and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Sitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects.
    Scientific reports, 2023, 06-16, Volume: 13, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Busulfan; Caspase 3; Humans; Inflammatio

2023
Regenerative Potential of Spermatogonial Stem Cells, Endothelial Progenitor Cells, and Epithelial Progenitor Cells of C57Bl/6 Male Mice with Metabolic Disorders.
    Bulletin of experimental biology and medicine, 2017, Volume: 163, Issue:2

    Topics: Animals; Busulfan; CD24 Antigen; CD52 Antigen; Endothelial Progenitor Cells; Inflammation; Integrin

2017
Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours.
    Journal of neuroinflammation, 2019, Feb-05, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow Cells; Brain Neoplasms; Busulfan; Cell Line,

2019
Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation.
    Scientific reports, 2015, Dec-04, Volume: 5

    Topics: Adenosine Triphosphate; Animals; Busulfan; Carrier Proteins; Chemical and Drug Induced Liver Injury;

2015
THE LOCAL INFLAMMATORY RESPONSE IN PATIENTS WITH BLOOD DYSCRASIAS AS TESTED BY THE SKIN WINDOW TECHNIQUE.
    Bulletin - Sinai Hospital of Detroit, 1963, Volume: 11

    Topics: Busulfan; Hodgkin Disease; Inflammation; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte

1963
The effect of various immunosuppressive agents on the vascular and cellular response to carvageenan in the rat.
    The Journal of pathology, 1973, Volume: 109, Issue:2

    Topics: Animals; Azathioprine; Busulfan; Carrageenan; Chlorambucil; Cyclophosphamide; Edema; Immunosuppressi

1973