Page last updated: 2024-10-24

busulfan and Infection

busulfan has been researched along with Infection in 34 studies

Research Excerpts

ExcerptRelevanceReference
" We therefore assessed 83 patients (age, 16-70 years): 68 with acute leukemia (including 34 in remission and 34 with refractory disease) and 15 patients with myelodysplastic syndrome, in HCT trials using RIC with busulfan, fludarabine, and antithymocyte globulin."7.77Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome. ( Hwang, HJ; Jeon, M; Jung, AR; Kang, YA; Kim, DY; Kim, SH; Lee, JH; Lee, KH; Lee, YS; Seol, M; Shin, HJ; Yun, SC, 2011)
"Since 1997, 32 newly diagnosed multiple myeloma patients responsive to DAV chemotherapy were autografted with idarubicin-intensified busulphan-melphalan (ida-bu-mel)."7.73High-dose idarubicin, busulphan and melphalan for autologous stem cell transplantation in multiple myeloma responsive to DAV chemotherapy: comparison with a historical control. ( Baldacci, E; Capria, S; de Propris, MS; Meloni, G; Petrucci, MT; Pulsoni, A; Ribersani, M, 2006)
" We therefore assessed 83 patients (age, 16-70 years): 68 with acute leukemia (including 34 in remission and 34 with refractory disease) and 15 patients with myelodysplastic syndrome, in HCT trials using RIC with busulfan, fludarabine, and antithymocyte globulin."3.77Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome. ( Hwang, HJ; Jeon, M; Jung, AR; Kang, YA; Kim, DY; Kim, SH; Lee, JH; Lee, KH; Lee, YS; Seol, M; Shin, HJ; Yun, SC, 2011)
"Since 1997, 32 newly diagnosed multiple myeloma patients responsive to DAV chemotherapy were autografted with idarubicin-intensified busulphan-melphalan (ida-bu-mel)."3.73High-dose idarubicin, busulphan and melphalan for autologous stem cell transplantation in multiple myeloma responsive to DAV chemotherapy: comparison with a historical control. ( Baldacci, E; Capria, S; de Propris, MS; Meloni, G; Petrucci, MT; Pulsoni, A; Ribersani, M, 2006)
" Graft-versus-host disease prophylaxis consisted of cyclosporine and a short course of methotrexate."3.71A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome. ( Kabisch, H; Kröger, N; Krüger, W; Renges, H; Schetelig, J; Schrum, J; Siegert, W; Stute, N; Zabelina, T; Zander, AR, 2001)
" Graft-versus-host disease (GVHD) prophylaxis consisted of T-cell depletion with IgM monoclonal antibody T10B9 plus complement and posttransplant cyclosporine-A."3.69Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia. ( Baxter-Lowe, LA; Bunin, N; Camitta, B; Casper, J; Garbrecht, F; Hunter, J; Lawton, C; Murray, K; Pietryga, D; Truitt, R, 1995)
"Twenty-five patients with hematologic malignancies were treated with busulfan (16 mg/kg) and cyclophosphamide (50 mg/kg x 3 days) as conditioning for bone marrow transplantation using marrow from serologically matched, DR locus genotypically identical unrelated donors."3.69Unrelated donor bone marrow transplantation without T cell depletion using a chemotherapy only condition regimen. Low incidence of failed engraftment and severe acute GVHD. ( Brodsky, I; Bulova, S; Crilley, P; Marks, DI; Styler, MJ; Topolsky, D, 1996)
"The toxic effects of high-dose busulfan (16 mg/kg) and cyclophosphamide (200 mg/kg) with autologous or syngeneic bone marrow rescue were evaluated in 19 patients (11 with acute myelocytic leukemia, one with acute lymphocytic leukemia, one with acute myelofibrosis, two with chronic myelocytic leukemia, one with Hodgkin's disease, and three with non-Hodgkin's lymphoma)."3.67Preliminary results of high-dose busulfan and cyclophosphamide with syngeneic or autologous bone marrow rescue. ( Braine, HG; Kaizer, H; Lu, C; Santos, GW; Saral, R; Tutschka, PJ, 1984)
"Besides high rates of manageable infections due to late immune recovery, transplantation with CD34+ immunoselected grafts in HRNB children was feasible and did not affect long-term hematopoiesis."2.76CD34+ immunoselection of autologous grafts for the treatment of high-risk neuroblastoma. ( Berger, M; Demeocq, F; Halle, P; Kanold, J; Leverger, G; Marabelle, A; Merlin, E; Paillard, C; Piguet, C; Rousseau, R; Stephan, JL; Tchirkov, A, 2011)
"Exacerbation of infection during aplasia was observed in 3 patients; inflammatory flare at the infection site during neutrophil engraftment in 2: all 5 patients belonged to the subgroup of 9 with pre-existing infection."2.41Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000. ( Belohradsky, BH; Blanche, S; Bordigoni, P; Cant, A; Di Bartolomeo, P; Fischer, A; Flood, T; Gungor, T; Landais, P; Müller, S; Nagler, A; Ozsahin, H; Passwell, JH; Porta, F; Seger, RA; Slavin, S; Wulffraat, N; Zintl, F, 2002)
"Only viral infections were significantly increased in the non-TBI group."1.48Long-term outcomes of total body irradiation plus cyclophosphamide versus busulfan plus cyclophosphamide as conditioning regimen for acute lymphoblastic leukemia: a comparative study. ( Anagnostopoulos, A; Apostolou, C; Athanasiadou, A; Batsis, I; Bousiou, Z; Bouziana, S; Chatziioannou, K; Constantinou, V; Douka, V; Gavriilaki, E; Gianouzakos, V; Iskas, M; Lalayanni, C; Mallouri, D; Papathanasiou, M; Sakellari, I; Sotiropoulos, D; Yannaki, E, 2018)
" Plasma concentrations of BU at steady state (C(SS)BU) during the dosing interval were measured for each patient."1.30Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation. ( Anasetti, C; Appelbaum, FR; Bensinger, WI; Bowden, R; Bryant, E; Buckner, CD; Chauncey, T; Clift, RA; Deeg, HJ; Doney, KC; Flowers, M; Gooley, T; Hansen, JA; Martin, PJ; McDonald, GB; Nash, R; Petersdorf, EW; Radich, J; Sanders, JE; Schoch, G; Slattery, JT; Soll, E; Stewart, P; Storb, R; Storer, B; Sullivan, KM; Thomas, ED; Witherspoon, RP, 1997)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19907 (20.59)18.7374
1990's6 (17.65)18.2507
2000's13 (38.24)29.6817
2010's6 (17.65)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
D'Angelo, CR1
Hall, A1
Woo, KM1
Kim, K2
Longo, W1
Hematti, P1
Callander, N1
Kenkre, VP1
Mattison, R1
Juckett, M1
Modi, D1
Singh, V1
Kim, S1
Ayash, L2
Deol, A1
Ratanatharathorn, V2
Uberti, JP1
Jung, SH1
Lee, JJ1
Kim, JS1
Min, CK1
Choi, Y1
Eom, HS1
Joo, YD1
Kim, SH2
Kwak, JY1
Kang, HJ1
Lee, JH3
Lee, HS1
Mun, YC1
Moon, JH1
Sohn, SK1
Park, SK1
Park, Y1
Shin, HJ2
Yoon, SS1
Sakellari, I1
Gavriilaki, E1
Chatziioannou, K1
Papathanasiou, M1
Mallouri, D1
Batsis, I1
Bousiou, Z1
Bouziana, S1
Constantinou, V1
Douka, V1
Apostolou, C1
Iskas, M1
Lalayanni, C1
Athanasiadou, A1
Sotiropoulos, D1
Yannaki, E1
Gianouzakos, V1
Anagnostopoulos, A1
Mallhi, K1
Orchard, PJ1
Miller, WP1
Cao, Q1
Tolar, J1
Lund, TC1
Hamadani, M1
Blum, W1
Phillips, G1
Elder, P1
Andritsos, L1
Hofmeister, C1
O'Donnell, L1
Klisovic, R1
Penza, S1
Garzon, R1
Krugh, D1
Lin, T1
Bechtel, T1
Benson, DM1
Byrd, JC1
Marcucci, G1
Devine, SM1
Ulrickson, M1
Aldridge, J1
Kim, HT1
Hochberg, EP1
Hammerman, P1
Dube, C1
Attar, E1
Ballen, KK1
Dey, BR1
McAfee, SL1
Spitzer, TR1
Chen, YB1
Atallah, E1
Abrams, J1
Bentley, G1
Abidi, M1
Uberti, J1
Marabelle, A1
Merlin, E1
Halle, P1
Paillard, C1
Berger, M1
Tchirkov, A1
Rousseau, R1
Leverger, G1
Piguet, C1
Stephan, JL1
Demeocq, F1
Kanold, J1
Lee, KH1
Kim, DY1
Seol, M1
Lee, YS1
Kang, YA1
Jeon, M1
Hwang, HJ1
Jung, AR1
Yun, SC1
Seger, RA1
Gungor, T1
Belohradsky, BH1
Blanche, S1
Bordigoni, P1
Di Bartolomeo, P1
Flood, T1
Landais, P1
Müller, S1
Ozsahin, H1
Passwell, JH1
Porta, F1
Slavin, S3
Wulffraat, N1
Zintl, F1
Nagler, A3
Cant, A1
Fischer, A1
Saito, T1
Kanda, Y1
Nakai, K1
Kim, SW1
Arima, F1
Kami, M1
Tanosaki, R1
Tobinai, K1
Wakasugi, H1
Heike, Y1
Mineishi, S1
Takaue, Y1
Massenkeil, G1
Nagy, M1
Le Coutre, P1
Heine, F1
Rosen, O1
Dörken, B1
Arnold, R1
Capria, S1
Petrucci, MT1
Pulsoni, A1
Ribersani, M1
Baldacci, E1
de Propris, MS1
Meloni, G1
Kiefer, T1
Krüger, WH1
Schüler, F1
Lotze, C1
Hirt, C1
Dölken, G1
Rodriguez, R1
Nademanee, A1
Ruel, N1
Smith, E1
Krishnan, A1
Popplewell, L1
Zain, J1
Patane, K1
Kogut, N1
Nakamura, R1
Sarkodee-Adoo, C1
Forman, SJ1
Lu, C1
Braine, HG1
Kaizer, H1
Saral, R1
Tutschka, PJ1
Santos, GW1
Deeg, HJ4
Storb, R2
Prentice, R1
Fritz, TE1
Weiden, PL1
Sale, GE1
Graham, TC1
Thomas, ED4
Clift, RA4
Buckner, CD4
Bryant, E4
Anasetti, C3
Bensinger, WI4
Bowden, R3
Doney, KC3
Fisher, LD2
Casper, J1
Camitta, B1
Truitt, R1
Baxter-Lowe, LA1
Bunin, N1
Lawton, C1
Murray, K1
Hunter, J1
Pietryga, D1
Garbrecht, F1
Hansen, JA2
Anderson, JE1
Appelbaum, FR2
Schoch, G2
Gooley, T2
Chauncey, T2
Topolsky, D1
Crilley, P1
Styler, MJ1
Bulova, S1
Brodsky, I1
Marks, DI1
Slattery, JT1
Radich, J1
Storer, B1
Soll, E1
Flowers, M1
Martin, PJ1
McDonald, GB1
Nash, R1
Petersdorf, EW1
Sanders, JE1
Stewart, P1
Sullivan, KM1
Witherspoon, RP1
Varadi, G2
Naparstek, E2
Samuel, S1
Or, R2
Bornhäuser, M1
Thiede, C1
Schuler, U1
Platzbecker, U1
Freiberg-Richter, J1
Helwig, A1
Plettig, R1
Röllig, C1
Naumann, R1
Kroschinsky, F1
Neubauer, A1
Ehninger, G1
Openshaw, H1
Lund, BT1
Kashyap, A1
Atkinson, R1
Sniecinski, I1
Weiner, LP1
Forman, S1
Morecki, S1
Gelfand, Y1
Engelhard, D1
Akerstein, A1
Kröger, N1
Schetelig, J1
Zabelina, T1
Krüger, W1
Renges, H1
Stute, N1
Schrum, J1
Kabisch, H1
Siegert, W1
Zander, AR1
Thompson, EN1
Soothill, JF1
Seidel, HJ1
Ward, HP1
Block, MH1
Saslaw, S1
Carlisle, HN1
Marcovitch, H1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Decitabine Followed by Bone Marrow Transplant and High-Dose Cyclophosphamide for the Treatment of Relapsed and Refractory Acute Myeloid Neoplasms[NCT01707004]Phase 220 participants (Actual)Interventional2013-05-16Completed
A Phase 2, Open-label, Prospective, Multicenter Study to Evaluate the Efficacy of Intravenous Busulfan and Melphalan as a Conditioning Regimen in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation[NCT01923935]Phase 2105 participants (Anticipated)Interventional2013-01-31Recruiting
Prospective Study of Combined ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT[NCT02677181]Phase 4100 participants (Actual)Interventional2016-01-31Completed
Immunomonitoring of Children With Neuroblastoma for the Development of Antitumor Immunotherapy Strategies[NCT01295762]35 participants (Actual)Interventional2011-05-31Active, not recruiting
NON-T-CELL DEPLETED HLA-HAPLOIDENTICAL FAMILIAL DONOR HEMATOPOIETIC CELL TRANSPLANTATION AFTER REDUCED INTENSITY CONDITIONING[NCT00521430]30 participants (Anticipated)Interventional2004-04-30Completed
HLA-HAPLOIDENTICAL FAMILIAL DONOR HEMATOPOIETIC CELL TRANSPLANTATION AFTER REDUCED INTENSITY CONDITIONING OF BUSULFAN, FLUDARABINE, AND ANTI-THYMOCYTE GLOBULIN FOR ADULT PATIENTS WITH HEMATOLOGIC MALIGNANCIES AND MYELODYSPLASTIC SYNDROME - A PHASE 2 STUDY[NCT00732316]Phase 254 participants (Actual)Interventional2008-04-30Completed
Phase I Trial of Haploidentical Natural Killer (NK) Cells in Combination With Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)[NCT03366064]Phase 15 participants (Actual)Interventional2017-11-09Completed
A Prospective Study Evaluating the Efficacy of the Allogeneic Hematopoietic Cell Transplantation With Antithymocyte Globulin (ATG)-Based Conditioning of Adult Acute Lymphoblastic Leukemia in First / Second Complete Hematologic Remission[NCT02428517]20 participants (Actual)Observational2015-04-30Terminated (stopped due to The PI resigned the institute, and the rest investigators at the institute decided to terminate the study.)
Allogeneic HCT From Donor-sources of Matched-sibling, Matched-unrelated, or Haploidentical-family Donors Using Uniform Conditioning Regimen of Busulfan, Fludarabine, and Antithymocyte Globulin for AML in Remission - an Observational Study[NCT03337568]110 participants (Anticipated)Observational2017-04-01Recruiting
HLA-Haploidentical Hematopoietic Cell Transplantation and Subsequent Donor Natural Killer Cell Infusion in Refractory Acute Leukemia - A Phase 1-2a STUDY[NCT01795378]Phase 1/Phase 256 participants (Actual)Interventional2013-02-28Completed
Safety and Efficacy of Ibritumomab Tiuxetan (Zevalin®) in Association With a Fludarabine Based Reduced Conditioning Regimen and Allogenic Stem Cell Support in Chemo-sensitive Relapsed CD20 Positive Aggressive Non-Hodgkin's Lymphoma Patients.[NCT00607854]Phase 231 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cumulative Incidence of Chronic GVHD According to BMTCTN

Will be summarized with a proportion and a 95% confidence interval. (NCT01707004)
Timeframe: Up to 1 year

Interventionpercentage (Number)
Decitabine + Bone Marrow Transplant40.7

Cumulative Incidence of Grade III-IV Acute GVHD

Determined by the standard bone marrow transplant (BMT) Clinical Trials Network criteria (BMTCTN). Will be analyzed using KM method, a Graft versus Host Disease (GVHD) grade III-IV will be obtained from the KM estimates along with 95% confidence intervals. (NCT01707004)
Timeframe: Day 100

Interventionpercentage of participants (Number)
Decitabine + Bone Marrow Transplant27.8

Number of Participants With Complete Remission After Transplantation

(NCT01707004)
Timeframe: Up to 1 year

InterventionParticipants (Count of Participants)
Decitabine + Bone Marrow Transplant14

Number of Participants With Primary Graft Failure

Defined as less than 5% donor chimerism in the cluster of differentiation (CD)3 and CD33 selected cell populations at any time after transplantation. Will be analyzed using KM method. (NCT01707004)
Timeframe: Day 30

InterventionParticipants (Count of Participants)
Decitabine + Bone Marrow Transplant0

Overall Survival (OS)

Will be analyzed using Kaplan-Meier (KM) method, and OS will be obtained from the KM estimates along with 95% confidence intervals. (NCT01707004)
Timeframe: Day 100

Interventionpercentage of participants (Number)
Decitabine + Bone Marrow Transplant64.7

Percentage of Participants With Platelet Recovery by Day 30

Platelet recovery is defined as the first day of a platelet count greater than 20,000/mm^3 with no platelet transfusions. Will be summarized with mean and standard deviation or median and interquartile range, and the change will be tested using a one-sample paired t-test at a two-tailed significance level of 0.05. (NCT01707004)
Timeframe: Up to day 30

Interventionpercentage with plt engraftment, day 30 (Number)
Decitabine + Bone Marrow Transplant58

Progression Free Survival

(NCT01707004)
Timeframe: Up to 1 year

Interventiondays (Median)
Decitabine + Bone Marrow Transplant141

Time to Neutrophil Recovery

Defined as achieving an absolute neutrophil count (ANC) greater than or equal to 500/ul for three consecutive measurements on different days. Will be summarized with mean and standard deviation or median and interquartile range, and the change will be tested using a one-sample paired t-test at a two-tailed significance level of 0.05. (NCT01707004)
Timeframe: Up to 1 year

Interventiondays (Mean)
Decitabine + Bone Marrow Transplant16

Reviews

3 reviews available for busulfan and Infection

ArticleYear
Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000.
    Blood, 2002, Dec-15, Volume: 100, Issue:13

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodie

2002
Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia.
    Blood, 1994, Dec-15, Volume: 84, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Combined Modalit

1994
The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome.
    Medicine, 1971, Volume: 50, Issue:5

    Topics: Adrenal Cortex Hormones; Alkaline Phosphatase; Androgens; Anemia; Animals; Blood Cell Count; Blood C

1971

Trials

8 trials available for busulfan and Infection

ArticleYear
Decitabine induction with myeloablative conditioning and allogeneic hematopoietic stem cell transplantation in high-risk patients with myeloid malignancies is associated with a high rate of infectious complications.
    Leukemia research, 2020, Volume: 96

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; De

2020
Phase 2 Study of an Intravenous Busulfan and Melphalan Conditioning Regimen for Autologous Stem Cell Transplantation in Patients with Multiple Myeloma (KMM150).
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:5

    Topics: Administration, Intravenous; Adult; Aged; Busulfan; Female; Humans; Infections; Male; Melphalan; Mid

2018
Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adult; Aged; Animals; Anti-Infective Agents; Antilymphocyte Serum; Busulfan; Disease Susceptibility;

2009
CD34+ immunoselection of autologous grafts for the treatment of high-risk neuroblastoma.
    Pediatric blood & cancer, 2011, Volume: 56, Issue:1

    Topics: Antigens, CD34; Busulfan; Child; Follow-Up Studies; Hematopoiesis; Hematopoietic Stem Cell Transplan

2011
Immune reconstitution following reduced-intensity transplantation with cladribine, busulfan, and antithymocyte globulin: serial comparison with conventional myeloablative transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busul

2003
Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia.
    Blood, 1994, Dec-15, Volume: 84, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Combined Modalit

1994
Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide.
    Blood, 1994, Sep-15, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Bilirubin; Bone Marrow Transplantation; Busulfan; Child; Creatinine; Cyclophospha

1994
Allogeneic marrow transplantation for myelodysplastic syndrome with advanced disease morphology: a phase II study of busulfan, cyclophosphamide, and total-body irradiation and analysis of prognostic factors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow

1996

Other Studies

24 other studies available for busulfan and Infection

ArticleYear
Comparison of myeloablative and reduced intensity conditioning unrelated donor allogeneic peripheral blood stem cell transplant outcomes for AML using thymoglobulin for GVHD prophylaxis.
    Annals of hematology, 2021, Volume: 100, Issue:4

    Topics: Aged; Allografts; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Humans; Immunosuppr

2021
Long-term outcomes of total body irradiation plus cyclophosphamide versus busulfan plus cyclophosphamide as conditioning regimen for acute lymphoblastic leukemia: a comparative study.
    Annals of hematology, 2018, Volume: 97, Issue:10

    Topics: Adult; Age Factors; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Follow-Up Studies; Gr

2018
Non-myeloablative conditioning for second hematopoietic cell transplantation for graft failure in patients with non-malignant disorders: a prospective study and review of the literature.
    Bone marrow transplantation, 2017, Volume: 52, Issue:5

    Topics: Adolescent; Adrenoleukodystrophy; Busulfan; Child; Child, Preschool; Graft Rejection; Graft Survival

2017
Busulfan and cyclophosphamide (Bu/Cy) as a preparative regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma: a single-institution experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Busulfan; Combined

2009
Long term follow-up of allogeneic stem cell transplantation in patients with myelodysplastic syndromes using busulfan, cytosine arabinoside, and cyclophosphamide.
    American journal of hematology, 2010, Volume: 85, Issue:8

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Foll

2010
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Nonmyeloablative stem cell transplantation in patients with ALL and AML results in low nonrelapse mortality despite high rate of infections and GVHD.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5, Issue:5

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Contraindications; Cyclosporine; Female; Follo

2004
High-dose idarubicin, busulphan and melphalan for autologous stem cell transplantation in multiple myeloma responsive to DAV chemotherapy: comparison with a historical control.
    Acta haematologica, 2006, Volume: 115, Issue:1-2

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

2006
The modification of high-dose therapy shortens the duration of neutropaenia by delay of leucocyte nadir.
    Bone marrow transplantation, 2006, Volume: 37, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Infec

2006
Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Cause of Death; Cohort Studies; Cyclophosphamide; Disease-Free Su

2006
Preliminary results of high-dose busulfan and cyclophosphamide with syngeneic or autologous bone marrow rescue.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transp

1984
Increased cancer risk in canine radiation chimeras.
    Blood, 1980, Volume: 55, Issue:2

    Topics: Aging; Animals; Bone Marrow Transplantation; Busulfan; Central Nervous System Diseases; Cyclophospha

1980
Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Actuarial Analysis; Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cycl

1995
Unrelated donor bone marrow transplantation without T cell depletion using a chemotherapy only condition regimen. Low incidence of failed engraftment and severe acute GVHD.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Actuarial Analysis; Acute Disease; Adult; Anti-Infective Agents; Bone Marrow Transplantation; Busulf

1996
Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Cyclophosphamide; Female; Graft Reject

1997
Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma.
    Bone marrow transplantation, 2000, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2000
Dose-reduced conditioning for allogeneic blood stem cell transplantation: durable engraftment without antithymocyte globulin.
    Bone marrow transplantation, 2000, Volume: 26, Issue:2

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Disease-Free Survival; Female; G

2000
Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:5A

    Topics: Adult; Autoantibodies; Autoantigens; Autoimmune Diseases; Brain; Busulfan; Cells, Cultured; Combined

2000
Immune reconstitution following allogeneic stem cell transplantation in recipients conditioned by low intensity vs myeloablative regimen.
    Bone marrow transplantation, 2001, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; C

2001
A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antilymphocyte Serum; Bone Marrow; Busulfan; Cell

2001
Chronic granulomatous disease: quantitative clinicopathological relationships.
    Archives of disease in childhood, 1970, Volume: 45, Issue:239

    Topics: Adolescent; Anemia; Arthritis; Blood Proteins; Body Height; Body Weight; Busulfan; Child; Child, Pre

1970
Target-cell characterization for Rauscher leukemia virus in vivo.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Animals; Bone Marrow Cells; Busulfan; Cell Division; Clone Cells; Endotoxins; Erythrocytes; Erythrop

1973
Nonhuman primates in evaluation of hematotoxicity.
    Annals of the New York Academy of Sciences, 1969, Jul-03, Volume: 162, Issue:1

    Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug-Related Side Effects and Adver

1969
Chronic granulomatous disease of childhood.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Anti-Bacterial Agents; Busulfan; Child; Child, Preschool; Chronic Disease; Coloring Agents; Female;

1970