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busulfan and Graft-Versus-Host Disease

busulfan has been researched along with Graft-Versus-Host Disease in 731 studies

Research Excerpts

ExcerptRelevanceReference
" Here we explored in 121 patients, mostly with advanced stage diseases, a sirolimus-based, calcineurin-inhibitor-free prophylaxis of graft-versus-host disease (GvHD) to allow the infusion of unmanipulated peripheral blood stem cell (PBSC) grafts from partially HLA-matched family donors (TrRaMM study, Eudract 2007-5477-54)."9.20Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors. ( Assanelli, A; Battaglia, M; Bernardi, M; Bondanza, A; Bonini, C; Bordignon, C; Carbone, MR; Carrabba, M; Ciceri, F; Clerici, D; Corti, C; Crocchiolo, R; Crotta, A; Crucitti, L; Ferraro, A; Fleischhauer, K; Forcina, A; Giglio, F; Guggiari, E; Locatelli, F; Lorusso, A; Lunghi, F; Marcatti, M; Marktel, S; Mastaglio, S; Messina, C; Noviello, M; Olek, S; Oliveira, G; Patriarca, F; Peccatori, J; Roncarolo, MG; Rossini, S; Stanghellini, MT; Tassara, M; Vago, L; Zecca, M, 2015)
"For chemosensitive advanced high-risk B-cell lymphoma, the addition of (90)Y-Ibritumomab tiuxetan to a RIC regimen based on fludarabine, busulfan and antithymocyte globulin followed by allogeneic transplant is safe and highly effective."9.2090Y-ibritumomab tiuxetan, fludarabine, busulfan and antithymocyte globulin reduced-intensity allogeneic transplant conditioning for patients with advanced and high-risk B-cell lymphomas. ( Asselineau, J; Blaise, D; Bouabdallah, K; Bouabdallah, R; Ceballos, P; Chevalier, P; Doussau, A; Furst, S; Le Gouill, S; Milpied, N; Mohty, M; Tabrizi, R; Tournilhac, O; Vigouroux, S, 2015)
" Patients with hematologic malignancies for whom limited long-term survival was expected with standard therapy were administered an outpatient conditioning regimen of busulfan 3."9.20Nonmyeloablative allogeneic hematopoietic stem cell transplant for the treatment of patients with hematologic malignancies using busulfan, fludarabine, and total body irradiation conditioning is effective in an elderly and infirm population. ( Avraham, GP; Brammer, JE; Curtin, P; Frires, R; Gajewski, J; Hayes-Lattin, B; Kovacsovics, T; Leis, JF; Maziarz, RT; Meyers, G; Nemecek, E; Palmbach, G; Slater, S; Stentz, A; Subbiah, N, 2015)
"The clinical safety and efficacy of intravenous busulfan and fludarabine (IV Bu/Flu) myeloablative conditioning as well as graft-versus-host disease (GVHD) prophylaxis with high-dose, post-transplantation cyclophosphamide (PTCy) have been demonstrated independently in several single-institutional studies."9.19Multi-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning. ( Andersson, BS; Champlin, RE; de Lima, MJ; Furlong, T; Jones, RJ; Kanakry, CG; Luznik, L; Medeot, M; Mielcarek, M; O'Donnell, PV; Thall, PF; Wei, W, 2014)
"We aimed to evaluate the safety and efficacy of fludarabine (FLU) and pharmacokinetic-targeted busulfan (BU) as conditioning regimen for hematopoietic cell transplantation (HCT) in adult patients with acute lymphoid leukemia (ALL)."9.15Fludarabine and pharmacokinetic-targeted busulfan before allografting for adults with acute lymphoid leukemia. ( Alsina, M; Anasetti, C; Ayala, E; Di Nicola, M; Fernandez, H; Field, T; Janssen, W; Kharfan-Dabaja, MA; Ochoa, L; Perez, L; Perkins, J; Pidala, J; Raychaudhuri, J; Santarone, S, 2011)
"A total of 45 patients with primary myelodysplastic syndromes were conditioned with 3×14 g/m(2) treosulfan and 5×30 mg/m(2) fludarabine followed by allogeneic hematopoietic stem cell transplantation."9.15Reduced-toxicity conditioning with treosulfan and fludarabine in allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes: final results of an international prospective phase II trial. ( Baumgart, J; Beelen, DW; Blau, IW; Casper, J; Einsele, H; Finke, J; Freund, M; Giebel, S; Gramatzki, M; Holowiecki, J; Kienast, J; Larsson, K; Markiewicz, M; Mylius, HA; Pichlmeier, U; Repp, R; Ruutu, T; Schnitzler, M; Stelljes, M; Stuhler, G; Trenschel, R; Uharek, L; Volin, L; Zander, AR, 2011)
"We assessed the combination of sirolimus, tacrolimus, and low-dose methotrexate as acute graft-versus-host disease (aGVHD) prophylaxis after reduced-intensity conditioning (RIC) allogeneic peripheral blood stem cell (PBSC) transplantation from matched related (MRD, n = 46) and unrelated (URD, n = 45) donors."9.13Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. ( Alyea, EP; Antin, JH; Cutler, C; Ho, V; Kim, HT; Li, S; Soiffer, RJ, 2008)
"To reduce the incidence of graft-versus-host disease (GVHD), we added Thymoglobulin (THY) to dose-adjusted oral busulfan plus cyclophosphamide (targeted BUCY)."9.12Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen. ( Anasetti, C; Appelbaum, FR; Boeckh, M; Deeg, HJ; Doney, KC; Flowers, ME; Hansen, JA; Heimfeld, S; Kiem, HP; Martin, PJ; McCune, JS; Myerson, D; Nash, RA; O'Donnell, PV; Radich, JP; Sandmaier, BM; Scott, BL; Sorror, ML; Storb, R; Storer, BE; Warren, EH; Witherspoon, RP; Woolfrey, A, 2006)
" The preparative therapy consisted of busulfan, melphalan, and antithymocyte globulin, with cyclosporine and corticosteroids for graft-versus-host disease (GVHD) prophylaxis."9.11Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience. ( Brochstein, JA; Carter, SL; Frangoul, H; Goyal, RK; Horan, JT; Kamani, NR; Kapoor, N; Kernan, NA; Kurtzberg, J; Pietryga, D; Wagner, JE; Wall, DA, 2005)
"Decitabine is a hypomethylating agent that has activity in patients with leukemia."9.10Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. ( Andersson, B; Champlin, R; Couriel, D; de Lima, M; Donato, M; Gajewski, J; Giralt, S; Kantarjian, H; Khouri, I; Ravandi, F; Shahjahan, M; van Besien, K, 2003)
"Between October 1988 and December 1992, 167 patients with leukemia receiving marrow transplants from HLA-identical donors and conditioned with cyclophosphamide (120 mg/kg) were randomized to additional treatment with either busulfan (16 mg/kg, n = 88) or total body irradiation (TBI; n = 79)."9.07A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group. ( Lenhoff, S; Ljungman, P; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1994)
"To study the toxicity and potential efficacy of busulfan (BU) and cyclophosphamide (CY) as a conditioning regimen before allogeneic bone marrow transplantation (ABMT) in patients with multiple myeloma (MM)."9.07Phase I study of busulfan and cyclophosphamide in preparation for allogeneic marrow transplant for patients with multiple myeloma. ( Appelbaum, FR; Beatty, P; Bensinger, WI; Bianco, JA; Buckner, CD; Clift, RA; Dalton, W; Fefer, A; Petersen, FB; Singer, JW, 1992)
"The use of cyclosporine-A/methotrexate (CyA/MTX) for graft-versus-host disease (GVHD) prophylaxis is safe and effective for patients undergoing allogeneic bone marrow transplantation after preparation with cyclophosphamide and total body irradiation."9.07Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan/cyclophosphamide. ( Essell, JH; Halvorson, RD; Harman, GS; Johnson, RA; Rubinsak, JR; Snyder, MJ; Thompson, JM, 1992)
"Busulfan 16 mg/kg and cyclophosphamide 120 mg/kg were used as conditioning prior to allogeneic marrow transplantation in 50 adult patients with acute nonlymphocytic leukemia (ANLL), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML)."9.06Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen. ( Copelan, EA; Klein, JP; Tutschka, PJ, 1987)
"Cyclophosphamide plus total body irradiation (CYTBI) and oral busulfan plus cyclophosphamide (BUCY) are commonly used conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT) in patients with leukemia."8.87Cyclophosphamide plus total body irradiation compared with busulfan plus cyclophosphamide as a conditioning regimen prior to hematopoietic stem cell transplantation in patients with leukemia: a systematic review and meta-analysis. ( Dantkale, V; Gupta, T; Kannan, S; Laskar, S, 2011)
"Twenty-four children with beta-thalassemia major received abatacept at a dose of 10 mg/kg intravenously on days -1, +5, +14, and +28 after HSCT in addition to calcineurin inhibitors and methylprednisolone."8.02Graft-versus-host Disease Prophylaxis With Abatacept Reduces Severe Acute Graft-versus-host Disease in Allogeneic Hematopoietic Stem Cell Transplant for Beta-thalassemia Major With Busulfan, Fludarabine, and Thiotepa. ( Dandoy, CE; Davies, SM; El-Bietar, J; Grimley, MS; Khandelwal, P; Lane, A; Yeh, RF; Yu, L, 2021)
"The purpose of our study was to compare the safety and efficacy of hematopoietic cell transplantation (HCT) using fludarabine (Flu)-based reduced intensity conditioning (RIC) with busulfan (BU) or melphalan (Mel) for primary immunodeficiency diseases (PID)."8.02Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases. ( Aoki, Y; Ashiarai, M; Endo, A; Hiroki, H; Hoshino, A; Ichimura, T; Imai, K; Inoue, K; Inoue, M; Ishiwata, Y; Isoda, T; Kajiwara, M; Kamiya, T; Kanegane, H; Kawahara, Y; Matsumoto, K; Mitsuiki, N; Miyamoto, S; Miyawaki, R; Mizutani, S; Morio, T; Nagasawa, M; Nishimura, A; Okano, T; Okawa, T; Ono, S; Ono, T; Takagi, M; Tanaka-Kubota, M; Tezuka, M; Tomizawa, D; Tomoda, T; Ueyama, J; Yamagishi, C; Yamashita, M; Yanagimachi, M; Yasuhara, M, 2021)
" busulfan (Bu) has been the main conditioning regimens for allogeneic hematopoietic cell transplantation (alloHCT) for young patients with acute myelogenous leukemia (AML) eligible for a myeloablative conditioning (MAC) regimen."7.96Long-Term Outcomes of Patients with Acute Myelogenous Leukemia Treated with Myeloablative Fractionated Total Body Irradiation TBI-Based Conditioning with a Tacrolimus- and Sirolimus-Based Graft-versus-Host Disease Prophylaxis Regimen: 6-Year Follow-Up fro ( Al Malki, MM; Aldoss, I; Ali, H; Aribi, A; Armenian, S; Budde, E; Dadwal, S; Dandapani, S; Forman, SJ; Hui, S; Khaled, S; Marcucci, G; Mei, M; Mokhtari, S; Murata-Collins, J; Nakamura, R; Peng, K; Pullarkat, V; Salhotra, A; Sandhu, KS; Snyder, D; Spielberger, R; Stein, A; Teh, JB; Wong, J; Yang, D, 2020)
" We retrospectively analyzed in a population of 670 children receiving allo-HSCT for acute leukemia the occurrence of different late effects in function of the choice made between total body irradiation (TBI) and busulfan, as part of the preparative regimen."7.96Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospec ( Balduzzi, A; Calore, E; Fagioli, F; Faraci, M; Favre, C; Giorgiani, G; Locatelli, F; Pagliara, D; Prete, A; Quarello, P; Saglio, F; Tambaro, FP; Zecca, M, 2020)
"In classical reduced-intensity conditioning (RIC) regimens, including the fludarabine and busulphan (BF) combination, sirolimus and tacrolimus (SIR-TAC) as graft vs host disease (GVHD) prophylaxis has shown acceptable results."7.96Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis. ( Barba, P; Bosch Vilaseca, A; Bosch, F; Esquirol, A; Fox, ML; García-Cadenas, I; Hernandez-Boluda, JC; Martino, R; Montoro, J; Ortí, G; Pérez, AM; Piñana, JL; Roldán, E; Saavedra, S; Salamero, O; Sanz, J; Sierra, J; Solano, C; Valcarcel, D; Villacampa, G, 2020)
"Fludarabine and melphalan (Flu/Mel) has emerged as a more tolerable chemotherapy-based conditioning regimen compared with busulfan and cyclophosphamide (Bu/Cy) for allogeneic stem cell transplant (allo-hematopoietic stem cell transplantation (HSCT)) patients with acute myelogenous leukemia (AML)."7.88Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia. ( Connolly, EC; Dhere, V; Edelman, S; Esiashvili, N; Graiser, M; Khan, MK; Langston, A; Switchenko, JM; Waller, EK, 2018)
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)."7.81[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015)
"We aim to evaluate the clinical efficacy of a modified busulfan and cyclophosphamide (BU/CY) conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of hematologic malignancies."7.80Modified busulfan and cyclophosphamide conditioning regimen for allogeneic hematopoietic stem cell transplantation in the treatment of patients with hematologic malignancies. ( Liu, W; Mao, XF; Wan, DM; Zhao, XF, 2014)
" We therefore assessed 83 patients (age, 16-70 years): 68 with acute leukemia (including 34 in remission and 34 with refractory disease) and 15 patients with myelodysplastic syndrome, in HCT trials using RIC with busulfan, fludarabine, and antithymocyte globulin."7.77Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome. ( Hwang, HJ; Jeon, M; Jung, AR; Kang, YA; Kim, DY; Kim, SH; Lee, JH; Lee, KH; Lee, YS; Seol, M; Shin, HJ; Yun, SC, 2011)
" busulfan (Bu) is well tolerated and effective in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia (AML)."7.76The addition of 400 cGY total body irradiation to a regimen incorporating once-daily intravenous busulfan, fludarabine, and antithymocyte globulin reduces relapse without affecting nonrelapse mortality in acute myelogenous leukemia. ( Bahlis, NJ; Balogh, A; Brown, CB; Chaudhry, MA; Daly, A; Duggan, P; Geddes, M; Irish, W; Larratt, L; Quinlan, D; Russell, JA; Savoie, ML; Stewart, DA; Storek, J; Turner, AR; Zacarias, N, 2010)
"To analyze the results of idarubicin (IDA)- versus etoposide (VP16)-intensified myeloablative conditioning regimen in allogeneic hematopoietic stem cell transplantation (allo-SCT) for high-risk acute leukemia."7.75A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia. ( Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P, 2009)
" We did a retrospective, multicenter analysis to assess the feasibility of conditioning with fludarabine and treosulfan before allogeneic SCT in multiple myeloma patients."7.74Reduced-toxicity conditioning with fludarabine and treosulfan prior to allogeneic stem cell transplantation in multiple myeloma. ( Andreesen, R; Beelen, DW; Blau, IW; Casper, J; Einsele, H; Fauser, AA; Fietz, T; Freund, M; Hopfenmüller, W; Kanz, L; Keilholz, U; Knauf, W; Marinets, O; Ruutu, T; Schmidt-Hieber, M; Stuhler, G; Thiel, E; Trenschel, R; Uharek, L; Volin, L, 2007)
"The present clinical trial was undertaken to investigate the toxicity and antimyeloma activity of busulfan (BU) and cyclophosphamide (CY) at the maximum tolerated doses of, respectively, 16 mg/kg and 200 mg/kg (BU-CY 4) as conditioning therapy for allogeneic bone marrow transplantation (BMT) in 19 consecutive patients with multiple myeloma (MM)."7.70High-dose busulfan and cyclophosphamide are an effective conditioning regimen for allogeneic bone marrow transplantation in chemosensitive multiple myeloma. ( Bandini, G; Belardinelli, A; Benni, M; Bonini, A; Cavo, M; Gozzetti, A; Lemoli, RM; Motta, MR; Rizzi, S; Ronconi, S; Rosti, G; Tura, S; Zamagni, E, 1998)
" We reviewed our experience using busulfan and cyclophosphamide (CY), instead of TBI, as the preparative regimen for allogeneic BMT to study the incidence and relationship to graft-versus-host disease (GVHD) of post-treatment eosinophilia."7.69Eosinophilia after allogeneic bone marrow transplantation using the busulfan and cyclophosphamide preparative regimen. ( Bolwell, BJ; Kalaycioglu, ME, 1994)
"Preparative regimens containing busulfan (BU) followed by allogeneic bone marrow transplantation (BMT) were used in 27 consecutive patients with myelodysplastic syndromes (MDS)."7.68Busulfan-based regimens and allogeneic bone marrow transplantation in patients with myelodysplastic syndromes. ( Cronin, S; Dan, ME; de Planque, MM; Hussein, M; Karanes, C; Lum, LG; Mohamed, A; Ratanatharathorn, V; Schultz, KR; Uberti, J, 1993)
"Cutaneous graft-versus-host disease (GVHD) has been reported after administration of cyclosporine (CSP) after autologous bone marrow transplantation (ABMT) with unpurged marrow in patients with lymphoma."7.68Induction of cutaneous graft-versus-host disease by administration of cyclosporine to patients undergoing autologous bone marrow transplantation for acute myeloid leukemia. ( Altomonte, V; Farmer, ER; Hess, AD; Jones, RJ; Santos, GW; Vogelsang, GB; Yeager, AM, 1992)
"Fifty-one patients with acute nonlymphocytic leukemia (16 with end-stage disease, 17 in second or third remission or in early relapse, and 18 in first remission) were given infusions of HLA-identical sibling marrow after cytoreduction with high doses of busulfan and cyclophosphamide."7.66Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. ( Beschorner, WE; Bias, WB; Braine, HG; Brookmeyer, R; Burns, WH; Elfenbein, GJ; Kaizer, H; Santos, GW; Saral, R; Tutschka, PJ, 1983)
"Clofarabine has potent antileukemia activity and its inclusion in reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (HSCT) for acute leukemia could potentially improve outcomes."6.82Phase II Trial of Reduced-Intensity Busulfan/Clofarabine Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Acute Lymphoid Leukemia. ( Alyea, E; Ballen, KK; Chen, YB; Cutler, C; Dey, BR; Driscoll, J; El-Jawahri, A; Ho, VT; Hunnewell, C; Li, S; McAfee, SL; Poliquin, C; Saylor, M; Soiffer, RJ; Spitzer, TR, 2016)
"Complete bioavailability of i."6.70Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia. ( Anderlini, P; Andersson, BS; Champlin, RE; Couriel, D; de Lima, M; Gajewski, J; Madden, T; Thall, PF; Tran, HT; Wang, X, 2002)
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."6.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
"Myalgia was reported in 37 patients; 34 patients in the treosulfan group and 3 patients in the busulfan group (p = 0."5.62Treosulfan-induced myalgia in pediatric hematopoietic stem cell transplantation identified by an electronic health record text mining tool. ( Berghuis, D; Bredius, RGM; Buddingh, EP; Guchelaar, HJ; Lankester, AC; Mohseny, AB; Smiers, FJW; van der Stoep, MYEC; Zwaveling, J, 2021)
"Busulfan (Bu) is an alkylating agent routinely used for conditioning regimens before allogeneic stem cell transplantation (allo-SCT)."5.62Feasibility and Efficacy of a Pharmacokinetics-Guided Busulfan Conditioning Regimen for Allogeneic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis in Adult Patients with Hematologic Malignancie ( Bartoli, A; Bramanti, S; Castagna, L; De Gregori, S; De Philippis, C; Giordano, L; Mannina, D; Mariotti, J; Pieri, G; Roperti, M; Sarina, B; Valli, V, 2021)
"Factors independently associated with delayed puberty were extensive chronic GVHD (P = ."5.56Pubertal outcomes of children transplanted with allogeneic stem cells after myeloablative total body irradiation or busulfan: Influence of age and sex is confirmed, while a role of chronic graft-versus-host disease in delayed puberty onset is revealed. ( Dalle, JH; Lebon Labich, B; Leheup, B; Pochon, C; Weinhard, S; Wiedemann, A, 2020)
" Prophylactic T cell depletion via antithymocyte globulin (ATG) during ASCT conditioning is one of the standards of care for GVHD prophylaxis, although the optimal dosing strategy is still unclear."5.56Antithymocyte globulin administration in patients with profound lymphopenia receiving a PBSC purine analog/busulfan-based conditioning regimen allograft. ( Bene, MC; Blin, N; Chevallier, P; Debord, C; Dubruille, V; Duquesne, A; Eveillard, M; Garnier, A; Gastinne, T; Guillaume, T; Jullien, M; Le Bourgeois, A; Le Bris, Y; Le Gouill, S; Mahe, B; Moreau, P; Peterlin, P; Tessoulin, B; Touzeau, C; Wuilleme, S, 2020)
"Busulfan is a major component of chemotherapy conditioning in hematopoietic cell transplantation (HCT)."5.51Retrospective study of the digestive tract mucositis derived from myeloablative and non-myeloablative/reduced-intensity conditionings with busulfan in hematopoietic cell transplantation patient. ( Bezinelli, LM; Carvalho, DLC; Corrêa, L; da Silva, CC; Eduardo, FP; Ferreira, MH; Gobbi, M; Hamerschlak, N; Rosin, FCP, 2019)
"Thirty-four patients had thalassemia major and 4 had SCA."5.43Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies Using a Tailored Busulfan-Based Conditioning Regimen: Single-Center Experience. ( Ben-Arush, M; Elhasid, R; Khalil, A; Rowe, JM; Zaidman, I, 2016)
" The responses and adverse events of the 2 groups were assessed."5.34[Efficacy and toxicity of intravenous busulfan-based conditioning before allogeneic peripheral blood stem cell transplantation for leukemia]. ( Li, J; Luo, SK; Peng, AH; Tong, XZ; Xu, DR; Zhang, GC; Zheng, D; Zou, WY, 2007)
"Busulfan was given once daily."5.32Fludarabine and once-daily intravenous busulfan for allogeneic bone marrow transplantation for Chediak-Higashi syndrome. ( Chan, KW; Gomez Almaguer, D; Gordon, N; Mullen, CA; Tran, H; Worth, L, 2003)
" Graft-versus-host disease (GVHD) prophylaxis consisted of cyclosporine and mycophenolate for all patients, associated with ATG in 39 patients (76."5.30Thiotepa, Busulfan, and Fludarabine Conditioning Regimen in T Cell-Replete HLA-Haploidentical Hematopoietic Stem Cell Transplantation. ( Adaeva, R; Banet, A; Bastos, J; Battipaglia, G; Belhocine, R; Brissot, E; de Wyngaert, ZV; Duléry, R; Giannotti, F; Isnard, F; Lapusan, S; Ledraa, T; Legrand, O; Malard, F; Médiavilla, C; Mohty, M; Paviglianiti, A; Rubio, MT; Ruggeri, A; Sestili, S; Vekhoff, A, 2019)
"Twenty-five consecutive patients with acute myelogenous leukemia (AML) underwent 26 allogeneic bone marrow transplants at Hahnemann University Hospital."5.28Bone marrow transplantation following busulfan and cyclophosphamide for acute myelogenous leukemia. ( Bigler, R; Brodsky, I; Bulova, S; Crilley, P; Topolsky, D, 1990)
" For graft-versus-host disease (GVHD) prophylaxis, cyclosporine and methotrexate were administered."5.24Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission. ( Baek, S; Choi, EJ; Choi, Y; Jeon, M; Jo, JC; Joo, YD; Kang, YA; Kang, YL; Kim, DY; Kim, H; Kim, SH; Ko, SH; Lee, JH; Lee, KH; Lee, YS; Lim, SN; Park, HS; Seol, M; Yun, SC, 2017)
" Here we explored in 121 patients, mostly with advanced stage diseases, a sirolimus-based, calcineurin-inhibitor-free prophylaxis of graft-versus-host disease (GvHD) to allow the infusion of unmanipulated peripheral blood stem cell (PBSC) grafts from partially HLA-matched family donors (TrRaMM study, Eudract 2007-5477-54)."5.20Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors. ( Assanelli, A; Battaglia, M; Bernardi, M; Bondanza, A; Bonini, C; Bordignon, C; Carbone, MR; Carrabba, M; Ciceri, F; Clerici, D; Corti, C; Crocchiolo, R; Crotta, A; Crucitti, L; Ferraro, A; Fleischhauer, K; Forcina, A; Giglio, F; Guggiari, E; Locatelli, F; Lorusso, A; Lunghi, F; Marcatti, M; Marktel, S; Mastaglio, S; Messina, C; Noviello, M; Olek, S; Oliveira, G; Patriarca, F; Peccatori, J; Roncarolo, MG; Rossini, S; Stanghellini, MT; Tassara, M; Vago, L; Zecca, M, 2015)
"For chemosensitive advanced high-risk B-cell lymphoma, the addition of (90)Y-Ibritumomab tiuxetan to a RIC regimen based on fludarabine, busulfan and antithymocyte globulin followed by allogeneic transplant is safe and highly effective."5.2090Y-ibritumomab tiuxetan, fludarabine, busulfan and antithymocyte globulin reduced-intensity allogeneic transplant conditioning for patients with advanced and high-risk B-cell lymphomas. ( Asselineau, J; Blaise, D; Bouabdallah, K; Bouabdallah, R; Ceballos, P; Chevalier, P; Doussau, A; Furst, S; Le Gouill, S; Milpied, N; Mohty, M; Tabrizi, R; Tournilhac, O; Vigouroux, S, 2015)
" Patients with hematologic malignancies for whom limited long-term survival was expected with standard therapy were administered an outpatient conditioning regimen of busulfan 3."5.20Nonmyeloablative allogeneic hematopoietic stem cell transplant for the treatment of patients with hematologic malignancies using busulfan, fludarabine, and total body irradiation conditioning is effective in an elderly and infirm population. ( Avraham, GP; Brammer, JE; Curtin, P; Frires, R; Gajewski, J; Hayes-Lattin, B; Kovacsovics, T; Leis, JF; Maziarz, RT; Meyers, G; Nemecek, E; Palmbach, G; Slater, S; Stentz, A; Subbiah, N, 2015)
" AlloSCT was composed of RIC with busulfan/fludarabine and tacrolimus, sirolimus, and methotrexate as graft-versus-host disease (GVHD) prophylaxis."5.20Phase II Trial of Tandem High-Dose Chemotherapy with Autologous Stem Cell Transplantation Followed by Reduced-Intensity Allogeneic Stem Cell Transplantation for Patients with High-Risk Lymphoma. ( Abramson, J; Antin, JH; Armand, P; Barnes, J; Brown, J; Chen, YB; Cutler, C; Del Rio, C; Driscoll, J; El-Jawahri, A; Fisher, DC; Ho, VT; Hochberg, E; Jacobsen, E; Li, S; McAfee, S; Soiffer, R; Spitzer, TR; Takvorian, R, 2015)
" Graft-versus-host disease (GVHD) prophylaxis consisted of tacrolimus and methotrexate."5.19Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases: a prospective multicenter trial. ( Baker, KS; Burroughs, LM; Deeg, HJ; Delaney, C; Domm, J; Englund, JA; Flowers, ME; Giller, RH; Nemecek, ER; Rawlings, DJ; Shimamura, A; Skoda-Smith, S; Storb, R; Storer, BE; Talano, JA; Thakar, MS; Torgerson, TR; Woolfrey, AE, 2014)
"The clinical safety and efficacy of intravenous busulfan and fludarabine (IV Bu/Flu) myeloablative conditioning as well as graft-versus-host disease (GVHD) prophylaxis with high-dose, post-transplantation cyclophosphamide (PTCy) have been demonstrated independently in several single-institutional studies."5.19Multi-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning. ( Andersson, BS; Champlin, RE; de Lima, MJ; Furlong, T; Jones, RJ; Kanakry, CG; Luznik, L; Medeot, M; Mielcarek, M; O'Donnell, PV; Thall, PF; Wei, W, 2014)
"Fifty patients with high-risk hematologic malignancies, underwent an unmanipulated haploidentical bone marrow transplantation (BMT), followed by posttransplantation high-dose cyclophosphamide (PT-CY): the myeloablative (MA) conditioning consisted of thiotepa, busulfan, fludarabine (n = 35), or total body irradiation (TBI), fludarabine (n = 15)."5.17Unmanipulated haploidentical bone marrow transplantation and posttransplantation cyclophosphamide for hematologic malignancies after myeloablative conditioning. ( Bacigalupo, A; Ballerini, F; Bregante, S; Di Grazia, C; Dominietto, A; Geroldi, S; Ghiso, A; Gualandi, F; Lamparelli, T; Luchetti, S; Miglino, M; Raiola, AM; Van Lint, MT; Varaldo, R, 2013)
"We evaluated the incidence of GVHD, risk factors and the impact of graft composition on acute GVHD (aGVHD) in 92 children who underwent BMT for thalassemia following busulfan/cyclophosphamide (BUCY)-based conditioning regimens and GVHD prophylaxis with CSA/short-MTX and methylprednisolone."5.16Higher CD3(+) and CD34(+) cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia. ( Adorno, G; Alfieri, C; Andreani, M; Daniele, N; De Angelis, G; Del Proposto, G; Gallucci, C; Gaziev, J; Isgrò, A; Lanti, A; Lucarelli, G; Marziali, M; Paciaroni, K; Roveda, A; Saltarelli, F; Simone, MD; Sodani, P; Testi, M, 2012)
"Sixteen patients diagnosed with various hematologic malignancies participated in a phase II study evaluating the addition of rabbit antithymocyte globulin (rATG, Thymoglobulin(®)) to the hematopoietic cell transplant (HCT) conditioning regimen of IV fludarabine monophosphate (fludarabine) and targeted intravenous (IV) busulfan (fludarabine/(T)busulfan)."5.16A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients. ( Deeg, HJ; Furlong, T; Heimfeld, S; McCune, JS; O'Donnell, PV; Storer, B; Wang, J; Woodahl, EL, 2012)
" busulfan (Bu) and fludarabine (Flu) is a safe, reduced-toxicity conditioning program for acute myelogenous leukemia/myelodysplastic syndromes (AML/MDS), recurrent leukemia posttransplantation remains a problem."5.15Clofarabine ± fludarabine with once daily i.v. busulfan as pretransplant conditioning therapy for advanced myeloid leukemia and MDS. ( Alousi, A; Andersson, BS; Champlin, RE; de Lima, M; Hosing, C; Jones, RB; Kebriaei, P; Madden, T; Popat, U; Rondon, G; Shpall, EJ; Thall, PF; Valdez, BC; Wang, X; Worth, LL, 2011)
"We aimed to evaluate the safety and efficacy of fludarabine (FLU) and pharmacokinetic-targeted busulfan (BU) as conditioning regimen for hematopoietic cell transplantation (HCT) in adult patients with acute lymphoid leukemia (ALL)."5.15Fludarabine and pharmacokinetic-targeted busulfan before allografting for adults with acute lymphoid leukemia. ( Alsina, M; Anasetti, C; Ayala, E; Di Nicola, M; Fernandez, H; Field, T; Janssen, W; Kharfan-Dabaja, MA; Ochoa, L; Perez, L; Perkins, J; Pidala, J; Raychaudhuri, J; Santarone, S, 2011)
"A total of 45 patients with primary myelodysplastic syndromes were conditioned with 3×14 g/m(2) treosulfan and 5×30 mg/m(2) fludarabine followed by allogeneic hematopoietic stem cell transplantation."5.15Reduced-toxicity conditioning with treosulfan and fludarabine in allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes: final results of an international prospective phase II trial. ( Baumgart, J; Beelen, DW; Blau, IW; Casper, J; Einsele, H; Finke, J; Freund, M; Giebel, S; Gramatzki, M; Holowiecki, J; Kienast, J; Larsson, K; Markiewicz, M; Mylius, HA; Pichlmeier, U; Repp, R; Ruutu, T; Schnitzler, M; Stelljes, M; Stuhler, G; Trenschel, R; Uharek, L; Volin, L; Zander, AR, 2011)
"From 2002 to 2007, 103 patients with primary myelofibrosis or postessential thrombocythemia and polycythemia vera myelofibrosis and a median age of 55 years (range, 32-68 years) were included in a prospective multicenter phase 2 trial to determine efficacy of a busulfan (10 mg/kg)/fludarabine (180 mg/m(2))-based reduced-intensity conditioning regimen followed by allogeneic stem cell transplantation from related (n = 33) or unrelated donors (n = 70)."5.14Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation. ( Baurmann, H; Bethge, W; Bornhäuser, M; Brand, R; Burchert, A; Corradini, P; de Witte, TM; Dreger, P; Einsele, H; Holler, E; Kaufmann, M; Kobbe, G; Kröger, N; Kvasnicka, HM; Nagler, A; Niederwieser, D; Schubert, J; Schwerdtfeger, R; Stelljes, M; Thiele, J; Uharek, L; Wandt, H; Wulf, GG; Zabelina, T; Zander, AR, 2009)
"Combination tacrolimus and sirolimus graft-versus-host disease (GVHD) prophylaxis for allogeneic transplant in patients conditioned with a fractionated total body irradiation-based regimen has shown encouraging results."5.14A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens. ( Forman, SJ; Karanes, C; Kogut, N; Krishnan, AY; Nademanee, A; Nakamura, R; O'Donnell, M; Palmer, JM; Parker, P; Pullarkat, V; Rodriguez, R; Rosenthal, J; Senitzer, D; Shayani, S; Smith, E; Snyder, D, 2010)
"We report long-term results after a median follow-up of 105 months in 18 patients with multiple myeloma who received an intensified myeloablative conditioning regimen regimen consisting of modified total body irradiation, busulfan, cyclophosphamide, and antithymocyte globulin, followed by allogeneic stem cell transplantation (SCT)."5.14Long-term follow-up of an intensified myeloablative conditioning regimen with in vivo T cell depletion followed by allografting in patients with advanced multiple myeloma. ( Derigs, G; Einsele, H; Kröger, N; Krüll, A; Wandt, H; Zander, A, 2010)
"We assessed the combination of sirolimus, tacrolimus, and low-dose methotrexate as acute graft-versus-host disease (aGVHD) prophylaxis after reduced-intensity conditioning (RIC) allogeneic peripheral blood stem cell (PBSC) transplantation from matched related (MRD, n = 46) and unrelated (URD, n = 45) donors."5.13Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. ( Alyea, EP; Antin, JH; Cutler, C; Ho, V; Kim, HT; Li, S; Soiffer, RJ, 2008)
"In the current study, we have analyzed the efficacy of cyclosporine A (CSA) plus mycophenolate mofetil (MMF) as graft-versus-host disease (GVHD) prophylaxis in the fludarabine plus melphalan or busulfan reduced intensity regimen (RIC) setting in a series of 44 patients receiving allogeneic transplantation from an unrelated donor."5.13Reduced-intensity conditioning allogeneic transplantation from unrelated donors: evaluation of mycophenolate mofetil plus cyclosporin A as graft-versus-host disease prophylaxis. ( Caballero, D; Calvo, MV; de la Cámara, R; de Oteiza, JP; Heras, I; Martino, R; Pérez-Simón, JA; Rebollo, N; San Miguel, JF; Sierra, J; Valcarcel, D, 2008)
"To reduce the incidence of graft-versus-host disease (GVHD), we added Thymoglobulin (THY) to dose-adjusted oral busulfan plus cyclophosphamide (targeted BUCY)."5.12Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen. ( Anasetti, C; Appelbaum, FR; Boeckh, M; Deeg, HJ; Doney, KC; Flowers, ME; Hansen, JA; Heimfeld, S; Kiem, HP; Martin, PJ; McCune, JS; Myerson, D; Nash, RA; O'Donnell, PV; Radich, JP; Sandmaier, BM; Scott, BL; Sorror, ML; Storb, R; Storer, BE; Warren, EH; Witherspoon, RP; Woolfrey, A, 2006)
"This prospective study evaluated the outcomes of 75 successive patients receiving a FBC (fludarabine, busulphan, alemtuzumab) reduced-intensity conditioning (RIC) regimen for myelodysplastic syndromes (MDS) using volunteer unrelated donors(VUD)."5.12Outcomes of alemtuzumab-based reduced intensity conditioning stem cell transplantation using unrelated donors for myelodysplastic syndromes. ( Czepulkowski, B; Devereux, S; Duarte, RF; Ho, AY; Ingram, W; Kenyon, M; Lim, ZY; Mufti, GJ; Pagliuca, A; Pearce, L, 2006)
" Using conditioning consisting of fludarabine, busulfan, and anti-T-lymphocyte globulin and GVHD prophylaxis consisting of tacrolimus and methylprednisolone (1 mg/kg/day), 26 patients who had hematologic malignancies in an advanced stage or with a poor prognosis underwent transplantation using peripheral blood stem cells from an HLA-haploidentical donor (2-3 antigen mismatches in the graft-versus-host [GVH] direction) without T-cell depletion."5.12Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning. ( Fujioka, T; Hasei, H; Ikegame, K; Inoue, T; Kaida, K; Kawakami, M; Kawase, I; Kim, EH; Masuda, T; Ogawa, H; Taniguchi, Y; Yoshihara, S, 2006)
" Cyclosporine alone or cyclosporine with short-term methotrexate was randomized for graft-versus-host disease prophylaxis."5.12Prospective phase II trial to evaluate the complications and kinetics of chimerism induction following allogeneic hematopoietic stem cell transplantation with fludarabine and busulfan. ( Hara, M; Hino, M; Hori, A; Kami, M; Kanda, Y; Kim, SW; Mineishi, S; Mori, S; Ohashi, Y; Saito, AM; Suzuki, R; Takami, A; Takaue, Y; Takemoto, Y; Taniguchi, S; Yamaguchi, M; Yoshida, T, 2007)
" Methotrexate only was given for graft-versus-host disease (GVHD) prophylaxis."5.11Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival. ( Alonzo, TA; Barnard, DR; Buxton, AB; Gold, S; Kalousek, D; Kobrinsky, N; Lange, BJ; Neudorf, S; Sanders, J; Wallace, JD; Woods, WG, 2004)
" We report the results of allografting following conditioning with fludarabine, busulphan, and alemtuzumab in 62 patients with myelodysplastic syndromes (MDSs) (matched sibling donors [24] or volunteer unrelated donors [VUDs, 38])."5.11Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning. ( Devereux, S; Ho, AY; Kenyon, M; Mijovic, A; Mufti, GJ; Pagliuca, A; Parker, JE, 2004)
" Between March 1993 and June 2002, we treated 33 relapsed acute myelogenous leukemia (AML) patients with busulfan-based preparative regimens and selective TCD."5.11CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens. ( Andresen, S; Ball, E; Bolwell, B; Cook, D; Kalaycio, M; Kuczkowski, E; Pohlman, B; Rybicki, L; Sobecks, R, 2005)
" The preparative therapy consisted of busulfan, melphalan, and antithymocyte globulin, with cyclosporine and corticosteroids for graft-versus-host disease (GVHD) prophylaxis."5.11Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience. ( Brochstein, JA; Carter, SL; Frangoul, H; Goyal, RK; Horan, JT; Kamani, NR; Kapoor, N; Kernan, NA; Kurtzberg, J; Pietryga, D; Wagner, JE; Wall, DA, 2005)
"Decitabine is a hypomethylating agent that has activity in patients with leukemia."5.10Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. ( Andersson, B; Champlin, R; Couriel, D; de Lima, M; Donato, M; Gajewski, J; Giralt, S; Kantarjian, H; Khouri, I; Ravandi, F; Shahjahan, M; van Besien, K, 2003)
" The conditioning regimen was cyclophosphamide (160 mg/kg) and busulfan (10-14 mg/kg), followed by unmanipulated bone marrow (median of 5&10(8) cells/kg) and CyA (+MTX in two patients) for prophylaxis of graft-versus-host disease (GvHD)."5.09Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria. ( Bacigalupo, A; Benvenuto, F; Berisso, G; Bregante, S; Figari, O; Frassoni, F; Gualandi, F; Lamparelli, T; Mordini, N; Raiola, AM; Van Lint, MT, 2000)
" Cyclosporin A and short methotrexate were used for graft-versus-host disease (GVHD) prophylaxis."5.08Combined transplantation of allogeneic bone marrow and CD34+ blood cells. ( Arseniev, L; Bähre, O; Battmer, K; Berenson, RJ; Casper, J; Diedrich, H; Jacobs, R; Kadar, JG; Kühl, J; Link, H; Poliwoda, H; Schubert, J, 1995)
"67 consecutive patients undergoing transplantation with allogeneic bone marrow (donated by a relative) in whom busulfan plus cyclophosphamide was used as the preparative regimen and cyclosporine plus methotrexate was used to prevent graft-versus-host disease."5.08Ursodiol prophylaxis against hepatic complications of allogeneic bone marrow transplantation. A randomized, double-blind, placebo-controlled trial. ( Allerton, JP; Callander, N; Essell, JH; Halvorson, R; Harman, GS; Lew, V; Lewis, SK; Schroeder, MT; Snyder, M; Thompson, JM, 1998)
"Between October 1988 and December 1992, 167 patients with leukemia receiving marrow transplants from HLA-identical donors and conditioned with cyclophosphamide (120 mg/kg) were randomized to additional treatment with either busulfan (16 mg/kg, n = 88) or total body irradiation (TBI; n = 79)."5.07A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group. ( Lenhoff, S; Ljungman, P; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1994)
" Cyclosporine, methotrexate and prednisone were used for graft-versus-host disease (GVHD) prophylaxis."5.07Allogeneic marrow transplantation in patients with chronic myeloid leukemia in chronic phase following preparation with busulfan and cyclophosphamide. ( Angelucci, E; Baronciani, D; Erer, B; Galimberti, M; Gaziev, D; Giardini, C; Lucarelli, G; Polchi, P; Rapa, S; Ripalti, M, 1994)
"To study the toxicity and potential efficacy of busulfan (BU) and cyclophosphamide (CY) as a conditioning regimen before allogeneic bone marrow transplantation (ABMT) in patients with multiple myeloma (MM)."5.07Phase I study of busulfan and cyclophosphamide in preparation for allogeneic marrow transplant for patients with multiple myeloma. ( Appelbaum, FR; Beatty, P; Bensinger, WI; Bianco, JA; Buckner, CD; Clift, RA; Dalton, W; Fefer, A; Petersen, FB; Singer, JW, 1992)
" Based on this concept, 17 patients with refractory or relapsed leukemia or lymphoma undergoing either autologous or allogeneic bone marrow transplantation (BMT) were treated on a Phase I protocol using high doses of busulfan (16 mg/kg, days -10, -9, -8, -7) and cyclophosphamide (120 mg/kg, days -6, -5) followed by escalating doses of a 48-h continuous infusion of cytarabine (starting dose 1000 mg/m2/48 h, days -3, -2)."5.07Phase I study of busulfan, cyclophosphamide, and timed sequential escalating doses of cytarabine followed by bone marrow transplantation. ( Chandler, C; Devine, S; Geller, RB; Larson, RA; Myers, S; O'Toole, K; Park, CL; Topper, RL; Williams, SF, 1992)
"The use of cyclosporine-A/methotrexate (CyA/MTX) for graft-versus-host disease (GVHD) prophylaxis is safe and effective for patients undergoing allogeneic bone marrow transplantation after preparation with cyclophosphamide and total body irradiation."5.07Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan/cyclophosphamide. ( Essell, JH; Halvorson, RD; Harman, GS; Johnson, RA; Rubinsak, JR; Snyder, MJ; Thompson, JM, 1992)
"Busulfan 16 mg/kg and cyclophosphamide 120 mg/kg were used as conditioning prior to allogeneic marrow transplantation in 50 adult patients with acute nonlymphocytic leukemia (ANLL), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML)."5.06Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen. ( Copelan, EA; Klein, JP; Tutschka, PJ, 1987)
"Cyclophosphamide plus total body irradiation (CYTBI) and oral busulfan plus cyclophosphamide (BUCY) are commonly used conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT) in patients with leukemia."4.87Cyclophosphamide plus total body irradiation compared with busulfan plus cyclophosphamide as a conditioning regimen prior to hematopoietic stem cell transplantation in patients with leukemia: a systematic review and meta-analysis. ( Dantkale, V; Gupta, T; Kannan, S; Laskar, S, 2011)
"We retrospectively reviewed 17 consecutive bone marrow failure patients who underwent unrelated umbilical cord blood transplantation in our center and received conditioning regimens of Total Body Irradiation (TBI) or Busulfan (BU) + Fludarabine (FLU) + Cyclophosphamide (CY)."4.84Outcome of first or second transplantation using unrelated umbilical cord blood without ATG conditioning regimen for pediatric bone marrow failure disorders. ( Chen, X; Chen, Y; Guo, Y; Liu, F; Ren, Y; Wan, Y; Yang, W; Zhang, L; Zhu, X; Zou, Y, 2024)
" Cyclosporine- cyclophosphamide-mycophenolate mofetil was the most widely used graft-versus-host disease prophylaxis regimen."4.31A single-center experience of haploidentical stem cell transplantation in hematological malignancies. ( Akdemir, NB; Büyükaşık, Y; Demiroğlu, H; Göker, H; Haznedaroğlu, İC; Karakulak, EA; Malkan, ÜY; Özcebe, Oİ; Sayınalp, N; Tekin, F, 2023)
" We aimed to identify the risk factors that predict transplantation outcomes in patients with MF who underwent matched or mismatched allo-SCT using a uniform myeloablative conditioning regimen consisting of busulfan and fludarabine with tacrolimus and methotrexate-based graft-versus-host disease prophylaxis."4.31Transplantation Outcomes of Myelofibrosis with Busulfan and Fludarabine Myeloablative Conditioning. ( Alousi, AM; Bashir, Q; Champlin, RE; Hosing, C; Joseph, J; Kebriaei, P; Milton, DR; Olson, AL; Oran, B; Popat, UR; Qazilbash, MH; Ramdial, JL; Saini, NY; Shpall, EJ; Srour, SA, 2023)
"We report three adult patients with primary immunodeficiency (PID) treated with reduced-intensity allogenic hematopoietic cell transplantation (HCT) with fludarabine/treosulfan conditioning and graft-versus-host disease (GvHD) prophylaxis with alemtuzumab and a calcineurin inhibitor."4.12Treosulfan-based Reduced-intensity Allogeneic Hematopoietic Cell Transplantation in Adults With Primary Immunodeficiency: A Case Series. ( Arranto, C; Dalla Via, V; Heim, D; Junker, T; Matteazzi, F; Medinger, M; Passweg, JR; Recher, M; Stelmes, A; van den Berg, J, 2022)
" The graft-versus-host disease (GVHD) prophylaxis consisted of tacrolimus and short-term methotrexate."4.12Donor-derived diffuse large B-cell lymphoma after haploidentical stem cell transplantation for acute myeloid leukemia. ( Ishiguro, C; Kawashiri, A; Kurokawa, T; Maeda, Y; Mochizuki, K; Nakagawa, SI, 2022)
" Cyclosporine gave as preferred graft-versus-host disease prophylaxis with a short course of methotrexate."4.12Successful Allogeneic Peripheral Blood Stem Cell Transplantation in 4 Wiskott-Aldrich Syndrome Patients. ( Ahmed Nacer, R; Ait Ouali, D; Baazizi, M; Benakli, M; Bouarab, H; Hamladji, RM; Harieche, F; Mehdid, F; Rahmoune, N; Zerkout, S, 2022)
"Twenty-four children with beta-thalassemia major received abatacept at a dose of 10 mg/kg intravenously on days -1, +5, +14, and +28 after HSCT in addition to calcineurin inhibitors and methylprednisolone."4.02Graft-versus-host Disease Prophylaxis With Abatacept Reduces Severe Acute Graft-versus-host Disease in Allogeneic Hematopoietic Stem Cell Transplant for Beta-thalassemia Major With Busulfan, Fludarabine, and Thiotepa. ( Dandoy, CE; Davies, SM; El-Bietar, J; Grimley, MS; Khandelwal, P; Lane, A; Yeh, RF; Yu, L, 2021)
"The purpose of our study was to compare the safety and efficacy of hematopoietic cell transplantation (HCT) using fludarabine (Flu)-based reduced intensity conditioning (RIC) with busulfan (BU) or melphalan (Mel) for primary immunodeficiency diseases (PID)."4.02Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases. ( Aoki, Y; Ashiarai, M; Endo, A; Hiroki, H; Hoshino, A; Ichimura, T; Imai, K; Inoue, K; Inoue, M; Ishiwata, Y; Isoda, T; Kajiwara, M; Kamiya, T; Kanegane, H; Kawahara, Y; Matsumoto, K; Mitsuiki, N; Miyamoto, S; Miyawaki, R; Mizutani, S; Morio, T; Nagasawa, M; Nishimura, A; Okano, T; Okawa, T; Ono, S; Ono, T; Takagi, M; Tanaka-Kubota, M; Tezuka, M; Tomizawa, D; Tomoda, T; Ueyama, J; Yamagishi, C; Yamashita, M; Yanagimachi, M; Yasuhara, M, 2021)
"One hundred and sixty-one patients underwent haploidentical stem cell transplantation (haploSCT) with thiotepa, busulfan, and fludarabine conditioning followed by post-transplantation cyclophosphamide (PTCy) (on days +3 and +4) and tacrolimus as graft-versus-host disease prophylaxis."4.02Combining Three Different Pretransplantation Scores Improves Predictive Value in Patients after Haploidentical Stem Cell Transplantation with Thiotepa, Busulfan, and Fludarabine Conditioning and Post-Transplantation Cyclophosphamide. ( Cuesta, M; Esquirol, A; Ferrà, C; Garcia-Cadenas, I; Herruzo, B; Martino, R; Pascual, MJ; Pérez, A; Sierra, J; Torio, A; Torrent, A, 2021)
" busulfan (Bu) has been the main conditioning regimens for allogeneic hematopoietic cell transplantation (alloHCT) for young patients with acute myelogenous leukemia (AML) eligible for a myeloablative conditioning (MAC) regimen."3.96Long-Term Outcomes of Patients with Acute Myelogenous Leukemia Treated with Myeloablative Fractionated Total Body Irradiation TBI-Based Conditioning with a Tacrolimus- and Sirolimus-Based Graft-versus-Host Disease Prophylaxis Regimen: 6-Year Follow-Up fro ( Al Malki, MM; Aldoss, I; Ali, H; Aribi, A; Armenian, S; Budde, E; Dadwal, S; Dandapani, S; Forman, SJ; Hui, S; Khaled, S; Marcucci, G; Mei, M; Mokhtari, S; Murata-Collins, J; Nakamura, R; Peng, K; Pullarkat, V; Salhotra, A; Sandhu, KS; Snyder, D; Spielberger, R; Stein, A; Teh, JB; Wong, J; Yang, D, 2020)
"30) versus busulfan-based myeloablative regimens; were diagnosed with acute graft-versus-host disease (GVHD) with stage 2+ skin involvement (OR = 1."3.96Risk factors for the development of cutaneous melanoma after allogeneic hematopoietic cell transplantation. ( Battiwalla, M; Brazauskas, R; Buchbinder, D; Cahoon, EK; Curtis, RE; Engels, EA; Flowers, ME; Herr, MM; Morton, LM; Shaw, BE; Tecca, HR; Tucker, MA, 2020)
" busulfan and post-transplant graft-versus-host disease (GVHD) prophylaxis with cyclophosphamide, tacrolimus, and mycophenolate mofetil."3.96Hematopoietic Stem Cell Transplantation for Severe Thalassemia Patients from Haploidentical Donors Using a Novel Conditioning Regimen. ( Andersson, BS; Anurathapan, U; Charoenkwan, P; Chuansumrit, A; Hongeng, S; Iamsirirak, P; Jetsrisuparb, A; Lektrakul, Y; Meekaewkunchorn, A; Pakakasama, S; Pongphitcha, P; Rujkijyanont, P; Sanpakit, K; Sirachainan, N; Sirireung, S; Songdej, D; Sruamsiri, R; Surapolchai, P; Wahidiyat, PA, 2020)
" We retrospectively analyzed in a population of 670 children receiving allo-HSCT for acute leukemia the occurrence of different late effects in function of the choice made between total body irradiation (TBI) and busulfan, as part of the preparative regimen."3.96Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospec ( Balduzzi, A; Calore, E; Fagioli, F; Faraci, M; Favre, C; Giorgiani, G; Locatelli, F; Pagliara, D; Prete, A; Quarello, P; Saglio, F; Tambaro, FP; Zecca, M, 2020)
"In classical reduced-intensity conditioning (RIC) regimens, including the fludarabine and busulphan (BF) combination, sirolimus and tacrolimus (SIR-TAC) as graft vs host disease (GVHD) prophylaxis has shown acceptable results."3.96Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis. ( Barba, P; Bosch Vilaseca, A; Bosch, F; Esquirol, A; Fox, ML; García-Cadenas, I; Hernandez-Boluda, JC; Martino, R; Montoro, J; Ortí, G; Pérez, AM; Piñana, JL; Roldán, E; Saavedra, S; Salamero, O; Sanz, J; Sierra, J; Solano, C; Valcarcel, D; Villacampa, G, 2020)
"Fludarabine and melphalan (Flu/Mel) has emerged as a more tolerable chemotherapy-based conditioning regimen compared with busulfan and cyclophosphamide (Bu/Cy) for allogeneic stem cell transplant (allo-hematopoietic stem cell transplantation (HSCT)) patients with acute myelogenous leukemia (AML)."3.88Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia. ( Connolly, EC; Dhere, V; Edelman, S; Esiashvili, N; Graiser, M; Khan, MK; Langston, A; Switchenko, JM; Waller, EK, 2018)
"We successfully used a haploidentical transplantation protocol with posttransplant cyclophosphamide (CY) (50 mg/kg/d on days +3 and +4) for in vivo T-cell depletion in patients with mucopolysaccharidosis using reduced-intensive conditioning regimens, followed by a busulfan-based conditioning regimen, which included busulfan (12 to 16 mg/kg) and fludarabine(150 to 200 mg/m)+rabbit antihuman thymocyte globulin (7."3.88Posttransplant Cyclophosphamide for HLA-haploidentical Transplantation in Patients With Mucopolysaccharidosis. ( Feng, S; Li, J; Liu, R; Shi, X; Song, Z; Yue, Y, 2018)
"To further investigate the role of treosulfan conditioning in children, the EBMT Pediatric diseases working party performed a retrospective analysis of 193 children with hematological malignancies (ALL n = 71, AML n = 47, MDS/MPS n = 40, other leukemia/lymphoma n = 25) undergoing allogeneic HSCT following treosulfan between January 2005 and July 2010."3.83European Society for Blood and Marrow Transplantation Analysis of Treosulfan Conditioning Before Hematopoietic Stem Cell Transplantation in Children and Adolescents With Hematological Malignancies. ( Boztug, H; Cant, A; Glogova, E; Lankester, A; Peters, C; Pötschger, U; Skinner, R; Slatter, M; Sykora, KW; Veys, P; Wachowiak, J; Zecca, M, 2016)
" Of these, 33 received RIC with fludarabine, cyclophosphamide, and rituximab (FCR) and graft-versus-host disease (GVHD) prophylaxis with a calcineurin inhibitor and mini-methotrexate, and 61 received RIC with fludarabine and busulfan (FluBu) and GVHD prophylaxis with a calcineurin inhibitor and mycophenolate mofetil."3.83Reduced-Intensity Conditioning with Fludarabine, Cyclophosphamide, and Rituximab Is Associated with Improved Outcomes Compared with Fludarabine and Busulfan after Allogeneic Stem Cell Transplantation for B Cell Malignancies. ( Chinratanalab, W; Engelhardt, BG; Goodman, SA; Greer, JP; Jagasia, M; Kassim, AA; Kennedy, VE; Savani, BN; Sengsayadeth, S, 2016)
"The clinical data of 190 patients with hematological malignancies undergoing sUCBT between April 2000 and December 2013 at Department of Hematology, Anhui Provincial Hospital were retrospectively analyzed, of whom 156 received IMCR without ATG (IMCR group), including 79 patient receiving total body irradiation (TBI)/cytosine arabinoside (Ara-C)/cyclophosphamide (CY) regime, 47 receiving fludarabine (Flu)/busulfan (Bu)/CY regime, and 30 receiving Ara-C/Bu/CY regime, and all of the 156 received a combination of cyclosporine A (CsA) and mycophelonate mofetil (MMF) for the prophylaxis of graft-versus-host disease (GVHD); the remaining 34 patients received MCR (MCR group), 30 patients receiving Bu/CY regime, and 4 receiving TBI/CY regime, all using CsA/MMF±ATG or methotrexate (MTX) for the prophylaxis of GVHD."3.83[Comparison of intensified myeloablative conditioning regime without antithymocytic globulin (ATG) with myeloablative conditioning regime for single-unit unrelated umbilical cord blood transplantation in hematological malignancies]. ( Ding, KY; Geng, LQ; Han, YS; Liu, HL; Liu, X; Sun, ZM; Tang, BL; Tong, J; Wan, X; Wang, XB; Wang, ZY; Wu, JS; Wu, Y; Yang, HZ; Yao, W; Zhang, L; Zhang, XH; Zheng, CC; Zhu, WW; Zhu, XY, 2016)
"25 mg/kg/day on days -4 to -1) and graft-versus-host disease (GVHD) prophylaxis with tacrolimus and methotrexate were used in all patients."3.81A well-tolerated regimen of 800 cGy TBI-fludarabine-busulfan-ATG for reliable engraftment after unmanipulated haploidentical peripheral blood stem cell transplantation in adult patients with acute myeloid leukemia. ( Cho, BS; Cho, SG; Eom, KS; Jeon, YW; Kim, DW; Kim, HJ; Kim, JH; Kim, YJ; Lee, JW; Lee, S; Lee, SE; Min, CK; Min, WS; Park, CW; Shin, SH; Yahng, SA; Yoon, JH, 2015)
"To investigate the safety and efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for myelodysplastic syndrome (MDS) and secondary acute myelogenous leukemia (MDS-AML) using conditioning regimen with busulfan (Bu) and increased-dose of fludarabine (ID-Flu)."3.81[Combination of busulfan with increased-dose of fludarabine as conditioning regimen for MDS and MDS-AML patients with allo-HSCT]. ( Cen, X; Dong, Y; Li, Y; Liang, Z; Liu, W; Ou, J; Qiu, Z; Ren, H; Sun, Y; Wang, L; Wang, M; Wang, Q; Wang, W; Xu, W; Yin, Y; Yuan, J, 2015)
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)."3.81[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015)
"Conditioning regimen including fludarabine, intravenous busulfan (Bx), and 5 mg/kg total dose of rabbit antithymocyte globulin (r-ATG) (FBx-ATG) results in low incidence of graft-versus-host disease (GVHD) and non-relapse mortality (NRM) after allogeneic hematopoietic stem cell transplantation (Allo-HSCT) from HLA-matched related or unrelated donors (MUD)."3.80A conditioning platform based on fludarabine, busulfan, and 2 days of rabbit antithymocyte globulin results in promising results in patients undergoing allogeneic transplantation from both matched and mismatched unrelated donor. ( Blaise, D; Bouabdallah, R; Calmels, B; Castagna, L; Chabannon, C; Coso, D; Crocchiolo, R; D'Incan, E; Devillier, R; El-Cheikh, J; Etienne, A; Fürst, S; Granata, A; Harbi, S; Lemarie, C; Picard, C; Schiano, JM; Stoppa, AM; Vey, N, 2014)
"We aim to evaluate the clinical efficacy of a modified busulfan and cyclophosphamide (BU/CY) conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of hematologic malignancies."3.80Modified busulfan and cyclophosphamide conditioning regimen for allogeneic hematopoietic stem cell transplantation in the treatment of patients with hematologic malignancies. ( Liu, W; Mao, XF; Wan, DM; Zhao, XF, 2014)
" To prevent from graft-versus-host disease (GVHD), cyclosporin A and short term methotrexate (MTX) were used."3.80[The outcome of thirteen patients with nonmalignant hematologic diseases treated with HLA haploidentical stem cell transplantation]. ( Chen, T; Du, Q; Huang, Y; Lin, X; Lu, Z; Song, C; Sun, C; Tao, Y; Tu, S; Wu, B, 2014)
"Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML)."3.79Allogeneic hematopoietic stem-cell transplantation for acute myeloid leukemia in remission: comparison of intravenous busulfan plus cyclophosphamide (Cy) versus total-body irradiation plus Cy as conditioning regimen--a report from the acute leukemia worki ( Aljurf, M; Ben Othman, T; Campos, A; Labopin, M; Masszi, T; Michallet, M; Mohty, M; Nagler, A; Passweg, J; Poire, X; Rocha, V; Sengelov, H; Shimoni, A; Socie, G; Unal, A; Veelken, H; Volin, L; Yakoub-Agha, I, 2013)
" All the patients were conditioned with cyclophosphamide and busulfan, and treated with cyclosporin (CsA)/methotrexate (MTX)/mycophenolate mofetil (MMF) for graft-versus-host disease (GVHD) prophylaxis."3.77Imatinib combined with myeloablative allogeneic hematopoietic stem cell transplantation for advanced phases of chronic myeloid leukemia. ( Cai, Z; Han, X; He, J; Huang, H; Li, L; Lin, M; Luo, Y; Shi, J; Tan, Y; Xie, W; Ye, X; Zhao, Y; Zheng, Y, 2011)
" Graft-versus-host disease prophylaxis consisted of cyclosporine A and, for unrelated donors, short course of methotrexate and anti-T-lymphocyte globulin."3.77Allogeneic haematopoietic stem cell transplantation as therapy for chronic granulomatous disease--single centre experience. ( Baran, J; Czogała, W; Goździk, J; Krasowska-Kwiecień, A; Pituch-Noworolska, A; Skoczeń, S; Wędrychowicz, A; Wiecha, O; Zembala, M, 2011)
" We therefore assessed 83 patients (age, 16-70 years): 68 with acute leukemia (including 34 in remission and 34 with refractory disease) and 15 patients with myelodysplastic syndrome, in HCT trials using RIC with busulfan, fludarabine, and antithymocyte globulin."3.77Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome. ( Hwang, HJ; Jeon, M; Jung, AR; Kang, YA; Kim, DY; Kim, SH; Lee, JH; Lee, KH; Lee, YS; Seol, M; Shin, HJ; Yun, SC, 2011)
" busulfan (Bu) is well tolerated and effective in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia (AML)."3.76The addition of 400 cGY total body irradiation to a regimen incorporating once-daily intravenous busulfan, fludarabine, and antithymocyte globulin reduces relapse without affecting nonrelapse mortality in acute myelogenous leukemia. ( Bahlis, NJ; Balogh, A; Brown, CB; Chaudhry, MA; Daly, A; Duggan, P; Geddes, M; Irish, W; Larratt, L; Quinlan, D; Russell, JA; Savoie, ML; Stewart, DA; Storek, J; Turner, AR; Zacarias, N, 2010)
" Conditioning regimen consisted of busulfan (16 mg/kg) and cyclophosphamide (160 mg/kg) followed by cyclosporine and methotrexate as graft-versus-host disease prophylaxes."3.76Comparison of peripheral blood stem cell transplant with bone marrow transplant in class 3 thalassemic patients. ( Ashouri, A; Babaie, MH; Ghavamzadeh, A; Iravani, M; Khatami, F; Tavakoli, E, 2010)
" Graft-versus-host disease (GVHD) prophylaxis consisted of cyclosporine A (CsA) alone (n = 3) or in addition to methotrexate (MTX; n = 132) or mycophenolate mofetil (MMF; n = 51)."3.75Study of kidney function impairment after reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation. A single-center experience. ( Barba, P; Briones, J; Brunet, S; Delgado, J; Martino, R; Moreno, E; Piñana, JL; Sierra, J; Sureda, A; Valcárcel, D; Vega, M, 2009)
" The addition of melphalan was an independent risk factor; melphalan use combined with high busulfan exposure (AUC >74 mg x h/L) was associated with high incidences of aGVHD (58%), veno-occlusive disease (66%), and mucositis grade III-IV (26%)."3.75Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation. ( Bartelink, IH; Belitser, SV; Bierings, M; Boelens, JJ; Bredius, RG; Egberts, AC; Egeler, M; Knibbe, CA; Lankester, AC; Suttorp, MM; Zwaveling, J, 2009)
"To analyze the results of idarubicin (IDA)- versus etoposide (VP16)-intensified myeloablative conditioning regimen in allogeneic hematopoietic stem cell transplantation (allo-SCT) for high-risk acute leukemia."3.75A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia. ( Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P, 2009)
"We have reported a lower incidence of acute graft-versus-host disease (aGVHD) with a novel conditioning regimen using low-dose rabbit antithymocyte globulin (ATG; Thymoglobulin [TG]) with fludarabine and intravenous busulfan (FluBuTG)."3.74Outcomes following HSCT using fludarabine, busulfan, and thymoglobulin: a matched comparison to allogeneic transplants conditioned with busulfan and cyclophosphamide. ( Agovi, MA; Bacigalupo, A; Bahlis, NJ; Ballen, K; Bredeson, CN; Brown, C; Chaudhry, MA; Horowitz, MM; Kurian, S; Muehlenbien, CE; Quinlan, D; Rizzo, JD; Russell, JA; Savoie, L; Stewart, DA; Zhang, MJ, 2008)
" We did a retrospective, multicenter analysis to assess the feasibility of conditioning with fludarabine and treosulfan before allogeneic SCT in multiple myeloma patients."3.74Reduced-toxicity conditioning with fludarabine and treosulfan prior to allogeneic stem cell transplantation in multiple myeloma. ( Andreesen, R; Beelen, DW; Blau, IW; Casper, J; Einsele, H; Fauser, AA; Fietz, T; Freund, M; Hopfenmüller, W; Kanz, L; Keilholz, U; Knauf, W; Marinets, O; Ruutu, T; Schmidt-Hieber, M; Stuhler, G; Thiel, E; Trenschel, R; Uharek, L; Volin, L, 2007)
" Graft-versus-host disease (GVHD) prophylaxis included methotrexate, cyclosporine A, and rabbit antithymocyte globulin (Thymoglobulin)."3.74Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin. ( Bahlis, NJ; Balogh, A; Brown, CB; Chaudhry, MA; Geddes, M; Larratt, L; Quinlan, D; Russell, JA; Savoie, ML; Stewart, DA; Storek, J; Turner, AR, 2007)
" Conditioning regimens consisted of busulfan and cyclophosphamide, followed by cyclosporine +/- methotrexate for graft-versus-host disease (GVHD) prophylaxis."3.74Peripheral blood versus bone marrow as a source of hematopoietic stem cells for allogeneic transplantation in children with class I and II beta thalassemia major. ( Alimoghaddam, K; Ashouri, A; Ghaffari, H; Ghavamzadeh, A; Hadjibabaie, M; Iravani, M; Mahdavi, N; Mousavi, SA; Namdar, R; Nedaeifard, L; Shamshiri, A, 2008)
" Prophylaxis for graft-versus-host disease (GVHD) consisted of cyclosporine and methotrexate."3.73Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis. ( Furst, DE; Georges, GE; Henstorf, G; Langston, AA; Lee, J; McSweeney, PA; Nash, RA; Nelson, JL; Shulman, H; Storb, R; Sullivan, KM; Wener, M, 2006)
" In this report, we analyzed the outcome of 101 high-risk patients (70 hematologic and 31 nonhematologic malignancies) who received an HLA-identical sibling allo-SCT after RIC, including fludarabine, busulfan, and antithymocyte globulin (ATG)."3.72Graft-versus-host disease following allogeneic transplantation from HLA-identical sibling with antithymocyte globulin-based reduced-intensity preparative regimen. ( Bay, JO; Bilger, K; Blaise, D; Chabannon, C; Choufi, B; Coso, D; Faucher, C; Maraninchi, D; Mohty, M; Stoppa, AM; Tournilhac, O; Vey, N; Viens, P, 2003)
" Group A (n=5) received metronidazole as graft-versus-host disease prophylaxis during Bu treatment."3.72The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation. ( Aschan, J; Hassan, M; Hentschke, P; Ljungman, P; Nilsson, C; Ringdén, O, 2003)
"All patients were transplanted between 1992 and 1999, were >or= 18 years of age, received either cyclophosphamide/total-body irradiation (TBI) or busulfan/cyclophosphamide conditioning regimens, and received four doses of methotrexate for graft-versus-host disease prophylaxis post-transplant."3.72Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia. ( Bruemmer, B; Lloid, ME; Potter, JD; Robien, K; Schubert, MM; Ulrich, CM, 2004)
"Postulating favorable antileukemic effect with improved safety, we used intravenous busulfan and fludarabine as conditioning therapy for allogeneic hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS)."3.72Once-daily intravenous busulfan and fludarabine: clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS. ( Andersson, BS; Champlin, RE; Couriel, D; de Lima, M; Giralt, S; Jones, R; Korbling, M; Madden, T; Pierre, B; Russell, JA; Shahjahan, M; Shpall, EJ; Thall, PF; Wang, X, 2004)
"The results showed that the intravenous busulfan-based regimen had better compliance and less adverse effects including mucositis, hepatic toxicity, transplant-related hepatic veno-occlusive disease, and acute graft-versus-host disease than oral busulfan-based treatment."3.72Intravenous busulfan as preparative regimen in pediatric patients receiving hematopoietic stem cell transplantation: the preliminary experience in Taiwan. ( Bai, LY; Chang, CY; Chen, PM; Chiou, TJ; Hsiao, LT; Hung, GY; Lee, MY, 2004)
"Twelve patients with leukemia, including 4 in complete remission, whose HLAs were full matched with donors, and 8 with refractory leukemia, whose HLAs were mismatched, were transplanted with G-CSF mobilized allogeneic peripheral blood stem cells after conditioned with a regimen consisting of fludarabine (30 mg/m(2) x 6 days), busulfan (4 mg/kg x 2 days) and cyclophosphamide (30 approximately 60 mg/kg x 2 days) (FBC)."3.71[Application of FBC conditioning regimen in HLA haplotype peripheral blood stem cell transplantation]. ( Guo, K; Song, Z; Wu, B; Xiao, L; Yan, D; Yang, Y, 2002)
"Using nonmyeloablative, immunosuppressive, fludarabine (FLU)-based conditioning regimens, we have performed allogeneic peripheral blood stem cell transplants in 26 patients (8 with chronic myelogenous leukemia, 6 with acute myelogenous leukemia, 10 with acute lymphoblastic leukemia, 1 with myelodysplasia, and 1 with thalassemia major)."3.71Results of an outpatient-based stem cell allotransplant program using nonmyeloablative conditioning regimens. ( Cantú, OG; Gómez-Almaguer, D; González-Llano, O; Jaime-Pérez, JC; Ruiz-Argüelles, A; Ruiz-Argüelles, GJ, 2001)
" Graft-versus-host disease prophylaxis consisted of cyclosporine and a short course of methotrexate."3.71A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome. ( Kabisch, H; Kröger, N; Krüger, W; Renges, H; Schetelig, J; Schrum, J; Siegert, W; Stute, N; Zabelina, T; Zander, AR, 2001)
" Graft-versus-host disease (GVHD) prophylaxis was attempted with cyclosporine A (CYA) and methotrexate."3.70[Severe hepatic veno-occlusive disease (VOD) which was successfully treated with supportive therapy, but subsequently developed late-recurrence]. ( Hirabayashi, N; Ikeda, Y; Ishida, A; Matsuoka, S; Moriki, T; Okamoto, S; Wakui, M; Watanabe, R, 1998)
"The present clinical trial was undertaken to investigate the toxicity and antimyeloma activity of busulfan (BU) and cyclophosphamide (CY) at the maximum tolerated doses of, respectively, 16 mg/kg and 200 mg/kg (BU-CY 4) as conditioning therapy for allogeneic bone marrow transplantation (BMT) in 19 consecutive patients with multiple myeloma (MM)."3.70High-dose busulfan and cyclophosphamide are an effective conditioning regimen for allogeneic bone marrow transplantation in chemosensitive multiple myeloma. ( Bandini, G; Belardinelli, A; Benni, M; Bonini, A; Cavo, M; Gozzetti, A; Lemoli, RM; Motta, MR; Rizzi, S; Ronconi, S; Rosti, G; Tura, S; Zamagni, E, 1998)
" Graft-versus-host disease (GVHD) prophylaxis was cyclosporin, prednisolone and low-dose antithymocyte globulin."3.70Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin. ( Haghshenas, M; Khojasteh, HN; Ramzi, M; Zakerinia, M, 1999)
"The purpose of this study was to evaluate the influence of busulfan (BU) pharmacokinetics on survival, grades II-IV acute graft-versus-host disease (GVHD), non-relapse mortality (NRM) and relapse in a group composed of 45 children (<18 years) and seven adults with acute myeloid leukemia (AML) in first complete remission and undergoing hematopoietic stem cell transplantation (SCT)."3.70Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia. ( Baker, KS; Blazar, BR; Bostrom, B; DeFor, T; Ramsay, NK; Woods, WG, 2000)
" Graft-versus-host disease (GVHD) prophylaxis consisted of T-cell depletion with IgM monoclonal antibody T10B9 plus complement and posttransplant cyclosporine-A."3.69Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia. ( Baxter-Lowe, LA; Bunin, N; Camitta, B; Casper, J; Garbrecht, F; Hunter, J; Lawton, C; Murray, K; Pietryga, D; Truitt, R, 1995)
" We reviewed our experience using busulfan and cyclophosphamide (CY), instead of TBI, as the preparative regimen for allogeneic BMT to study the incidence and relationship to graft-versus-host disease (GVHD) of post-treatment eosinophilia."3.69Eosinophilia after allogeneic bone marrow transplantation using the busulfan and cyclophosphamide preparative regimen. ( Bolwell, BJ; Kalaycioglu, ME, 1994)
" For graft-versus-host disease prophylaxis patients received cyclosporin A (CSA) and methotrexate (MTX) (n=32), MTX alone (n=12), CSA and methylprednisone (n=5), or CSA alone (n=13)."3.69Long-term leukemia-free survival after allogeneic marrow transplantation in patients with acute myelogenous leukemia. ( Brugger, SA; Dieckmann, KU; Fischer, G; Geissler, K; Greinix, HT; Haas, O; Hinterberger, W; Hocker, P; Jager, U; Kalhs, P; Keil, F; Lechner, K; Linkesch, W; Mannhalter, C; Reiter, E; Schneider, B; Schwarzinger, I, 1996)
"Twenty-five patients with hematologic malignancies were treated with busulfan (16 mg/kg) and cyclophosphamide (50 mg/kg x 3 days) as conditioning for bone marrow transplantation using marrow from serologically matched, DR locus genotypically identical unrelated donors."3.69Unrelated donor bone marrow transplantation without T cell depletion using a chemotherapy only condition regimen. Low incidence of failed engraftment and severe acute GVHD. ( Brodsky, I; Bulova, S; Crilley, P; Marks, DI; Styler, MJ; Topolsky, D, 1996)
"Between September 1987 and December 1994, 80 patients with multiple myeloma (MM) received high-dose busulfan and cyclophosphamide without (n = 57) or with modified total body irradiation (n = 23) followed by marrow from allogeneic donors."3.69Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome. ( Anasetti, C; Appelbaum, FR; Barnett, T; Bensinger, WI; Buckner, CD; Chauncey, T; Clift, R; Shulman, H; Storb, R, 1996)
"Preparative regimens containing busulfan (BU) followed by allogeneic bone marrow transplantation (BMT) were used in 27 consecutive patients with myelodysplastic syndromes (MDS)."3.68Busulfan-based regimens and allogeneic bone marrow transplantation in patients with myelodysplastic syndromes. ( Cronin, S; Dan, ME; de Planque, MM; Hussein, M; Karanes, C; Lum, LG; Mohamed, A; Ratanatharathorn, V; Schultz, KR; Uberti, J, 1993)
"Cutaneous graft-versus-host disease (GVHD) has been reported after administration of cyclosporine (CSP) after autologous bone marrow transplantation (ABMT) with unpurged marrow in patients with lymphoma."3.68Induction of cutaneous graft-versus-host disease by administration of cyclosporine to patients undergoing autologous bone marrow transplantation for acute myeloid leukemia. ( Altomonte, V; Farmer, ER; Hess, AD; Jones, RJ; Santos, GW; Vogelsang, GB; Yeager, AM, 1992)
"Fifty-one patients with acute nonlymphocytic leukemia (16 with end-stage disease, 17 in second or third remission or in early relapse, and 18 in first remission) were given infusions of HLA-identical sibling marrow after cytoreduction with high doses of busulfan and cyclophosphamide."3.66Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. ( Beschorner, WE; Bias, WB; Braine, HG; Brookmeyer, R; Burns, WH; Elfenbein, GJ; Kaizer, H; Santos, GW; Saral, R; Tutschka, PJ, 1983)
"Strategies to reduce recurrence are urgently required."3.01Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia. ( Andrew, G; Byrne, J; Craddock, C; Crawley, C; Dillon, R; Freeman, SD; Gilleece, M; Hodgkinson, A; Hunter, A; Jackson, A; Khan, N; Loke, J; Malladi, R; Mason, J; McCarthy, N; Nagra, S; Parker, A; Pavlu, J; Peniket, A; Potter, V; Protheroe, R; Salim, R; Siddique, S; Tholouli, E; Vyas, P; Wheatley, K; Wilson, K, 2021)
"Most patients with juvenile myelomonocytic leukemia (JMML) are curable only with allogeneic hematopoietic cell transplantation (HCT)."2.87Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study. ( Cairo, MS; Cooper, T; Dang, H; Dvorak, CC; Gao, Y; Grupp, SA; Hirsch, B; Kahwash, S; Loh, ML; Mazor, T; Mehta, PA; Olshen, AB; Parker, JS; Patel, N; Pei, Q; Raimondi, S; Satwani, P; Skeens, M; Stieglitz, E; Wall, D, 2018)
"Busulfan levels were monitored to avoid excess toxicity."2.84Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study. ( Baker, KS; Boulad, F; Davies, SM; Guinan, E; Kernan, NA; Lane, A; Leemhuis, T; Lehmann, L; Margolis, D; Mehta, PA; Myers, K; O'Reilly, RJ; Prockop, SE; Scaradavou, A; Williams, DA, 2017)
" The efficacy and safety of both dosing strategies were compared using a systematic review and meta-analysis."2.82Fixed-dose administration and pharmacokinetically guided adjustment of busulfan dose for patients undergoing hematopoietic stem cell transplantation: a meta-analysis and cost-effectiveness analysis. ( Chen, C; Chen, T; Guo, J; He, X; Liu, M; Zheng, B, 2022)
"Clofarabine has potent antileukemia activity and its inclusion in reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (HSCT) for acute leukemia could potentially improve outcomes."2.82Phase II Trial of Reduced-Intensity Busulfan/Clofarabine Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Acute Lymphoid Leukemia. ( Alyea, E; Ballen, KK; Chen, YB; Cutler, C; Dey, BR; Driscoll, J; El-Jawahri, A; Ho, VT; Hunnewell, C; Li, S; McAfee, SL; Poliquin, C; Saylor, M; Soiffer, RJ; Spitzer, TR, 2016)
"Forty-three patients with high-risk hematologic malignancies (median age, 43 years) were enrolled between December 2011 and September 2013."2.82Posttransplantation cyclophosphamide for prevention of graft-versus-host disease after HLA-matched mobilized blood cell transplantation. ( Appelbaum, FR; Carpenter, PA; Flowers, ME; Furlong, T; Martin, PJ; McCune, JS; Mielcarek, M; O'Donnell, PV; Storb, R; Storer, BE, 2016)
" Fifty-eight patients (median age, 67 years; range, 54 to 76) received radioimmunotherapy followed by fludarabine 150 mg/m(2) and busulfan 8 mg/kg combined with either 75 mg (n = 26) or 50 mg (n = 32) alemtuzumab."2.80Reduced-Intensity Conditioning Combined with (188)Rhenium Radioimmunotherapy before Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: The Role of In Vivo T Cell Depletion. ( Bornhäuser, M; Ehninger, G; Kotzerke, J; Schetelig, J; Schneider, S; Strumpf, A; Wunderlich, G, 2015)
"Fifty-four patients with advanced hematologic malignancies were enrolled on this study."2.80Phase I/II Trial of Dose-Escalated Busulfan Delivered by Prolonged Continuous Infusion in Allogeneic Transplant Patients. ( Armistead, P; Chung, Y; Coghill, J; Comeau, T; Gabriel, D; Ivanova, A; Rao, K; Sarantopoulos, S; Serody, J; Shea, TC; Sheets, J; Walko, C; Wood, W, 2015)
"Busulfan was administered mainly intravenously and exceptionally orally from days -5 to -3."2.79Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study. ( Ahmad, I; Albert, MH; Belohradsky, BH; Bredius, R; Fasth, A; Fernandes, JF; Fischer, A; Gaspar, HB; Gennery, A; Gruhn, B; Güngör, T; Haddad, E; Hassan, M; Hough, R; Kentouche, K; Lachance, S; Moshous, D; Rentsch, K; Resnick, IB; Schanz, U; Schlegel, PG; Seger, R; Shaw, PJ; Slatter, M; Stepensky, P; Stussi, G; Teira, P; Telles da Cunha, JM; Vermont, C; Veys, P, 2014)
"Secondary myelodysplastic syndrome and acute myelogenous leukemia (sMDS/sAML) are the most serious secondary events occurring after immunosuppressive therapy in patients with aplastic anemia."2.79Hematopoietic stem cell transplantation in children and young adults with secondary myelodysplastic syndrome and acute myelogenous leukemia after aplastic anemia. ( Baumann, I; Führer, M; Furlan, I; Göhring, G; Niemeyer, CM; Nöllke, P; Schlegelberger, B; Schwarz, S; Strahm, B; Teigler-Schlegel, A; Walther, JU; Yoshimi, A, 2014)
"In AML patients, minimal residual disease (MRD; n = 10) at the time of HCT predicted higher relapse incidence (70% versus 18%) and lower OS (41% versus 79%) at 2 years, when compared with patients without MRD."2.79Treosulfan, fludarabine, and 2-Gy total body irradiation followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome and acute myeloid leukemia. ( Appelbaum, FR; Bar, M; Baumgart, J; Deeg, HJ; Delaney, C; Estey, EH; Fang, M; Gutman, J; Gyurkocza, B; Maziarz, RT; Milano, F; Nemecek, ER; Pagel, JM; Ramakrishnan, A; Sandmaier, BM; Scott, B; Storer, BE; Wood, B, 2014)
" We conducted a phase I/II controlled, adoptive, randomized study to determine the optimal dosing schedule of i."2.78Dose intensification of busulfan in the preparative regimen is associated with improved survival: a phase I/II controlled, randomized study. ( Anderlini, P; Bassett, R; Champlin, R; de Lima, M; Ganesan, P; Giralt, S; Kebriaei, P; Khouri, I; Parmar, S; Rondon, G; Thall, P, 2013)
" We sought to determine the safety of GO in combination with busulfan/cyclophosphamide (Bu/Cy) conditioning before allogeneic hematopoietic stem cell transplantation (alloSCT)."2.77A Phase I study of gemtuzumab ozogamicin (GO) in combination with busulfan and cyclophosphamide (Bu/Cy) and allogeneic stem cell transplantation in children with poor-risk CD33+ AML: a new targeted immunochemotherapy myeloablative conditioning (MAC) regim ( Baxter-Lowe, LA; Bhatia, M; Cairo, MS; Dela Cruz, F; Duffy, D; Foley, S; Garvin, JH; George, D; Hawks, R; Jin, Z; Le Gall, J; Morris, E; Satwani, P; Schwartz, J; van de Ven, C, 2012)
"Busulfan has a narrow therapeutic range, and in children, pharmacokinetic variability has been found to be high even after the use of intravenous (i."2.77Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling. ( Ahn, HS; Han, EJ; Jang, IJ; Jang, MK; Kang, HJ; Kim, H; Kim, NH; Lee, JW; Lee, SH; Park, KD; Shin, HY; Song, SH; Yu, KS; Yuk, YJ, 2012)
"Busulfan (1."2.77Phase II study of dose-modified busulfan by real-time targeting in allogeneic hematopoietic stem cell transplantation for myeloid malignancy. ( Atsuta, Y; Fukumoto, M; Inamoto, Y; Karasuno, T; Kohno, A; Kuwatsuka, Y; Miyamura, K; Morishita, Y; Murata, M; Nagafuji, K; Naoe, T; Saito, S; Sawa, M; Shimada, K; Suzuki, R; Taniguchi, S; Terakura, S; Yasuda, T, 2012)
" This treosulfan-based preparation proved to be safe and effective for thalassemia patients given allogeneic HSCT."2.77Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan. ( Bernardo, ME; Bertaina, A; Caocci, G; Contoli, B; Giorgiani, G; La Nasa, G; Locatelli, F; Mastronuzzi, A; Pagliara, D; Pinto, RM; Piras, E; Vacca, A; Zecca, M, 2012)
"The optimal pretransplant regimen for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in patients ≥ 55 years of age remains to be determined."2.76Myeloablative reduced-toxicity i.v. busulfan-fludarabine and allogeneic hematopoietic stem cell transplant for patients with acute myeloid leukemia or myelodysplastic syndrome in the sixth through eighth decades of life. ( Alatrash, G; Andersson, BS; Champlin, RE; Chiattone, A; de Lima, M; de Padua Silva, L; Giralt, SA; Hamerschlak, N; Hosing, C; Kebriaei, P; Kerbauy, F; Nieto, Y; Pelosini, M; Qazilbash, MH; Rondon, G; Saliba, RM; Wang, X; Xiao, L; Zhang, W, 2011)
"BU used to treat patients with acute lymphoblastic leukemia (ALL)."2.76Intravenous busulfan-cyclophosphamide as a preparative regimen before allogeneic hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia. ( Chen, YB; Hu, J; Shen, ZX; Tang, W; Wang, L; Zhao, WL, 2011)
"Older patients with advanced hematologic malignancies achieve satisfactory outcomes using either of these reduced intensity conditioning regimens."2.73Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial. ( Arora, M; Barker, JN; Blazar, BR; Burns, LJ; DeFor, T; Douek, D; MacMillan, ML; Markova, M; Miller, JS; Repka, T; Tan, Y; Wagner, JE; Weisdorf, DJ, 2007)
"Diagnosis was primary myelofibrosis in 18 patients and secondary myelofibrosis in 6 patients; in 4 of them, primary myelofibrosis evolved from polycythemia vera, and in 2 of them from essential thrombocythemia."2.73Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis. ( Bethge, W; Bornhäuser, M; de Witte, T; Kobbe, G; Kröger, N; Kvasnicka, HM; Schubert, J; Schwerdtfeger, R; Thiele, J; Zander, A, 2007)
" To decrease acute toxicities, we have prospectively evaluated a reduced intensity conditioning (RIC) regimen using targeted dosing of i."2.72Reduced intensity conditioning using intravenous busulfan, fludarabine and rabbit ATG for children with nonmalignant disorders and CML. ( Baxter-Lowe, LA; Cowan, M; Desantes, K; Englert, L; Horn, B; McMillan, A; Quinn, M, 2006)
"Busulfan was added at the dose of 4 mg/kg to 200 mg/kg cyclophosphamide in 81 patients (3-53 years, median 24) with aplastic anemia to reduce graft rejection."2.71Addition of low-dose busulfan to cyclophosphamide in aplastic anemia patients prior to allogeneic bone marrow transplantation to reduce rejection. ( Aranha, FJ; Bacigalupo, A; Chamone, DA; Da Silva, RL; De Souza, CA; Dulley, FL; Macedo, MC; Mehta, J; Ruiz, MA; Saboya, R; Sturaro, D; Vigorito, AC, 2004)
" qd is a safe and effective regimen for allogeneic transplantation and is at least clinically equivalent to every 6 h dosing schemes using either oral or parenteral Bu."2.71Modification of the Bu/Cy myeloablative regimen using daily parenteral busulfan: reduced toxicity without the need for pharmacokinetic monitoring. ( Agura, ED; Berryman, RB; Fay, JW; Mamlouk, K; Pineiro, LA; Sandler, I; Saracino, G; Vance, EA; White, M, 2005)
" Reduced-intensity allogeneic SCT may offer a less toxic approach to patients with AML."2.71Preliminary results of the safety of immunotherapy with gemtuzumab ozogamicin following reduced intensity allogeneic stem cell transplant in children with CD33+ acute myeloid leukemia. ( Bhatia, M; Bradley, B; Cairo, MS; Cooney, E; Del Toro, G; Foley, S; Garvin, J; George, D; Harrison, L; Hawks, R; Militano, O; Roman, E; Satwani, P; Unal, E; van de Ven, C; Wolownik, K, 2005)
"Complete bioavailability of i."2.70Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia. ( Anderlini, P; Andersson, BS; Champlin, RE; Couriel, D; de Lima, M; Gajewski, J; Madden, T; Thall, PF; Tran, HT; Wang, X, 2002)
" A dosage schedule based on body surface area should be used especially in young children to reduce the age-dependent difference in kinetics."2.70A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation: 500 mg/m(2) as a optimal total dose for conditioning. ( Aschan, J; Eber, S; Gungor, T; Hassan, M; Hassan, Z; Hentschke, P; Ljungman, P; Nilsson, C; Ringdén, O; Seger, R; Winiarski, J, 2002)
"Cladribine (2-CdA) is a purine analogue that exhibits activity against a variety of hematological malignancies and has a potent immunosuppressive effect."2.70Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma. ( Kami, M; Kanai, S; Kanda, Y; Kato, K; Kawano, Y; Makimoto, A; Matsubara, H; Mineishi, S; Nakai, K; Ogasawara, T; Ohnishi, T; Saito, T; Shoji, N; Takaue, Y; Tanosaki, R; Tobinai, K; Wakasugi, H, 2002)
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."2.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
"Leukemic recurrence was observed in eight patients."2.68Allogeneic bone marrow transplantation following a busulfan-based conditioning regimen in young children with acute lymphoblastic leukemia: a Cooperative Study of the Société Française de Greffe de Moelle. ( Bernaudin, F; Cornu, G; Demeocq, F; Donadieu, J; Esperou-Bourdeau, H; Mechinaud-Lacroix, F; Michel, G; Sadoun, A; Souillet, G; von Bueltzingsloewen, A, 1995)
"Fifty-two BMT institutions were sent a questionnaire asking for details of dosing for busulphan, cyclophosphamide (bu-cy), cyclosporin and methotrexate (CSA-MTX)."2.68Variability in determination of body weight used for dosing busulphan and cyclophosphamide in adult patients: results of an international survey. ( Grigg, A; Harun, MH; Szer, J, 1997)
"Busulphan (BU) pharmacokinetic (PK) studies in children undergoing bone marrow transplantation suggest that individual BU dosing may be necessary to optimise BU systemic exposure."2.68An improved limited sampling method for individualised busulphan dosing in bone marrow transplantation in children. ( Calderwood, S; Chattergoon, DS; Doyle, J; Freedman, MH; Klein, J; Koren, G; Saunders, EF, 1997)
"One hundred fifteen patients with chronic myelocytic leukemia (CML) were administered busulphan 4 mg/kg for 4 days and cyclophosphamide 60 mg/kg on each of 2 days (BuCy2) followed by allogeneic bone marrow transplantation from histocompatible sibling donors."2.67Treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation after preparation with BuCy2. ( Atkinson, K; Avalos, B; Biggs, JC; Concannon, AJ; Crilley, P; Dodds, A; Downs, K; Kapoor, N; Szer, J; Tutschka, P, 1992)
"One hundred twenty-seven patients with acute myelocytic leukemia (AML) were given busulfan 4 mg/kg on each of 4 days and cyclophosphamide 60 mg/kg on each of 2 days (BuCy2) followed by allogeneic bone marrow transplantation from an HLA-identical or one antigen disparate sibling."2.67Treatment for acute myelocytic leukemia with allogeneic bone marrow transplantation following preparation with BuCy2. ( Atkinson, K; Avalos, BR; Biggs, JC; Copelan, EA; Crilley, P; Cunningham, I; Kapoor, N; Klein, JP; Szer, J; Thompson, JM, 1991)
"Busulfan has a very narrow therapeutic index, and acute toxicity may be related to absorption and disposition of the drug and metabolites."2.44Busulfan use in hematopoietic stem cell transplantation: pharmacology, dose adjustment, safety and efficacy in adults and children. ( Bentur, Y; Hoffer, E; Krivoy, N; Lurie, Y; Rowe, JM, 2008)
"Exacerbation of infection during aplasia was observed in 3 patients; inflammatory flare at the infection site during neutrophil engraftment in 2: all 5 patients belonged to the subgroup of 9 with pre-existing infection."2.41Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000. ( Belohradsky, BH; Blanche, S; Bordigoni, P; Cant, A; Di Bartolomeo, P; Fischer, A; Flood, T; Gungor, T; Landais, P; Müller, S; Nagler, A; Ozsahin, H; Passwell, JH; Porta, F; Seger, RA; Slavin, S; Wulffraat, N; Zintl, F, 2002)
"To evaluate the toxic extramedullary morbidity of the conditioning treatment with BuCy for BMT, as well as the usefulness of pentoxyphyllin (PTX) and methylprednisolone (MP) in the prophylaxis of mucositis."2.39[Extramedullary toxicity in bone marrow transplantation using busulfan and cyclophosphamide conditioning]. ( Maldonado, J; Pascual, MJ, 1995)
"Such opportunistic viral infections, leading to either interstitial pneumonia or hemorrhagic gastroenteritis, are the major threat in the early recovery phase after engraftment has taken place."2.37Infections and immunodeficiency in bone marrow transplantation. ( Tutschka, PJ, 1988)
"For acute lymphoblastic leukemia (ALL) patients, total body irradiation (TBI)- based conditioning regimens are the first choice specially in young population."1.91Thiotepa, busulfan and fludarabine conditioning-regimen is a promising approach for older adult patients with acute lymphoblastic leukemia treated with allogeneic stem cell transplantation. ( Banet, A; Bazarbachi, A; Belhocine, R; Bonnin, A; Brissot, E; Duléry, R; El-Cheikh, J; Genthon, A; Labopin, M; Ledraa, T; Legrand, O; Malard, F; Memoli, M; Mohty, M; Sestili, S; Stocker, N; Van de Wyngaert, Z, 2023)
" Here, we compared post-transplant outcomes after individualized versus fixed busulfan dosage in intermediate-risk AML who achieved CR prior to allograft focusing on pre-transplant flow-MRD."1.91Individualized busulfan dosing improves outcomes compared to fixed-dose administration in pre-transplant minimal residual disease-positive acute myeloid leukemia patients with intermediate-risk undergoing allogeneic stem cell transplantation in CR. ( Ayuk, F; Bacher, U; Badbaran, A; Dadkhah, A; Freiberger, P; Janson, D; Klyuchnikov, E; Kröger, N; Langebrake, C; Massoud, R; Wolschke, C, 2023)
"All patients had high-risk hematologic malignancies, were younger than 20 years, and were in complete cytological remission at the time of allo-HSCT."1.91Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders. ( Andersson, BS; Anurathapan, U; Hongeng, S; Pakakasama, S; Pongpitcha, P; Sirachainan, N; Songdej, D; Tannumsaeung, S, 2023)
" We evaluated two myeloablative conditioning dosing ranges of intravenous (IV) busulfan (Bu) in combination with fludarabine in 70 patients."1.91Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation. ( Ahmad, S; Edgar, CM; Guo, M; Mcvey, CP; Mori, S; Patel, RD; Rivera-Robles, N; Varela, JC; Yi, F, 2023)
"Total body irradiation (TBI) at a dose of 12 Gy combined with cyclophosphamide (CyTBI12Gy) is one of the standard myeloablative regimens for patients with acute myeloid leukemia (AML) treated with allogeneic hematopoietic cell transplantation (allo-HCT)."1.91Fludarabine versus cyclophospamide in combination with myeloablative total body irradiation as conditioning for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study from the Acute Leukemia Working Party ( Arat, M; Bourhis, JH; Cornelissen, JJ; Giebel, S; Grillo, G; Hilgendorf, I; Kröger, N; Labopin, M; Maertens, J; Mohty, M; Nagler, A; Poiré, X; Salmenniemi, U; Savani, B; Schroeder, T; Spyridonidis, A; Swoboda, R, 2023)
"In conclusion, ATG and PTCy combined with Flu-based increased intensity conditioning regimen is effective for acute leukemia in children."1.91Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia. ( Cao, J; Chen, D; Li, S; Liu, X; Lu, Y; Pei, R; Wang, T; Xu, X; Ye, P; Zheng, ZZ, 2023)
" The prediction of transplantation-related mortality (TRM) using the Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI) score and an arbitrary upper age limit of 55 years for administering myeloablative conditioning (MAC) are common strategies to ensure a safe procedure."1.91Myeloablative Dose of Busulfan and Fludarabine Combined with In Vivo T Cell Depletion Is Safe and Effective Conditioning for Acute Myeloid Leukemia and Myelodysplastic Syndrome Patients. ( Alshehri, H; Anteh, S; Avenoso, D; Bourlon, C; Bouziana, S; Dazzi, F; de Farias, M; Dragoi, OD; Gameil, A; Hannah, G; Kenyon, M; Krishnamurthy, P; Kulasekararaj, A; Leung, YT; Mehra, V; Pagliuca, A; Potter, V; Serpenti, F; Shah, MN; Slonim, LB; Wood, H, 2023)
"We prospectively studied clofarabine-fludarabine-busulfan (CloFluBu)-conditioning in allogeneic hematopoietic cell therapy (HCT) for lymphoid and myeloid malignancies and hypothesized that CloFluBu provides a less toxic alternative to conventional conditioning regimens, with adequate antileukemic activity."1.72Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia: an effective, low toxicity, TBI-free conditioning regimen. ( Bierings, M; Boelens, JJ; Bresters, D; de Koning, CCH; Kollen, WJ; Lankester, AC; Lindemans, CA; Nierkens, S; Versluijs, AB, 2022)
"Optimal conditioning for adults with acute lymphoblastic leukemia (ALL) treated with haploidentical hematopoietic cell transplantation (haplo-HCT) and post-transplant cyclophosphamide has not been established so far."1.72Total body irradiation plus fludarabine versus thiotepa, busulfan plus fludarabine as a myeloablative conditioning for adults with acute lymphoblastic leukemia treated with haploidentical hematopoietic cell transplantation. A study by the Acute Leukemia W ( Aljurf, M; Angelucci, E; Arat, M; Bernasconi, P; Giebel, S; Labopin, M; Mohty, M; Nagler, A; Pavlu, J; Peric, Z; Pioltelli, P; Rigacci, L; Risitano, A; Rovira, M; Saccardi, R; Savani, BN; Sica, S; Socié, G; Spyridonidis, A; Swoboda, R; Tischer, J; Van Gorkom, G; Vitek, A, 2022)
" In 2019, we changed Bu dosing from 4×/day (Bu-4) to 1×/day (Bu-1) for ease of application."1.72Impact of busulfan pharmacokinetics on outcome in adult patients receiving an allogeneic hematopoietic cell transplantation. ( Battegay, R; Halter, J; Heim, D; Medinger, M; Passweg, JR; Rentsch, KM; Seydoux, C, 2022)
" PT was graded using Common Terminology Criteria for Adverse Events version 5."1.72Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients. ( Chen, YH; Duncan, CN; Lehmann, LE; Liu, KX; Marcus, KJ; Margossian, S; Moore, N; Poux, N; Shin, KY; Whangbo, JS, 2022)
" Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is curative and safe at the pediatric age but remains underperformed in adults."1.72Curative allogeneic hematopoietic stem cell transplantation following reduced toxicity conditioning in adults with primary immunodeficiency. ( Asnafi, V; Catherinot, É; Cheminant, M; Couderc, LJ; Fischer, A; Hermine, O; Jeljeli, M; Lanternier, F; Lortholary, O; Mahlaoui, N; Marçais, A; Moshous, D; Neven, B; Picard, C; Salvator, H; Suarez, F; van Endert, P, 2022)
"However, the risk for subsequent malignant neoplasms (SMN) remains a significant concern."1.72Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial. ( Albert, MH; Bader, P; Basu, O; Beier, R; Burkhardt, B; Classen, CF; Claviez, A; Corbacioglu, S; Deubzer, HE; Eichinger, A; Glogova, E; Greil, J; Gruhn, B; Güngör, T; Kafa, K; Kühl, JS; Lang, P; Lange, BS; Meisel, R; Müller, I; Peters, C; Poetschger, U; Sauer, MG; Schlegel, PG; Schulz, A; Stachel, D; Strahm, B; Wawer, A, 2022)
"Myalgia was reported in 37 patients; 34 patients in the treosulfan group and 3 patients in the busulfan group (p = 0."1.62Treosulfan-induced myalgia in pediatric hematopoietic stem cell transplantation identified by an electronic health record text mining tool. ( Berghuis, D; Bredius, RGM; Buddingh, EP; Guchelaar, HJ; Lankester, AC; Mohseny, AB; Smiers, FJW; van der Stoep, MYEC; Zwaveling, J, 2021)
"We compared transplant outcomes of 708 acute myeloid leukemia (AML) patients receiving haploidentical allogeneic hematopoietic-cell transplantation using thiotepa/busulfan/fludarabine (TBF) conditioning with posttransplant cyclophosphamide (ptCy), to 2083 patients receiving matched unrelated donor (MUD) transplantation using fludarabine/busulfan (FB) conditioning and in vivo T-cell depletion."1.62Comparable outcomes of haploidentical transplant with TBF conditioning versus matched unrelated donor with fludarabine/busulfan conditioning for acute myeloid leukemia. ( Angelucci, E; Bazarbachi, A; Berceanu, A; Blaise, D; Bulabois, CE; Ceballos, P; El Cheikh, J; Forcade, E; Kröger, N; Labopin, M; Mielke, S; Mohty, M; Nagler, A; Rambaldi, A; Savani, B; Socié, G; Spyridonidis, A; Yakoub-Agha, I, 2021)
"Busulfan was administered IV and according to body weight."1.62Comparison of Total Body Irradiation-based Versus Chemotherapy-based Conditionings for Early Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Children With ALL. ( Bas, EG; Celen, S; Daloglu, H; Hazar, V; Kabakci, C; Karasu, GT; Pashayev, D; Pehlivan, B; Uygun, V; Yalcin, K; Yesilipek, A; Zhumatayev, S, 2021)
"Busulfan (Bu) is an alkylating agent routinely used for conditioning regimens before allogeneic stem cell transplantation (allo-SCT)."1.62Feasibility and Efficacy of a Pharmacokinetics-Guided Busulfan Conditioning Regimen for Allogeneic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis in Adult Patients with Hematologic Malignancie ( Bartoli, A; Bramanti, S; Castagna, L; De Gregori, S; De Philippis, C; Giordano, L; Mannina, D; Mariotti, J; Pieri, G; Roperti, M; Sarina, B; Valli, V, 2021)
"The most common primary cancer was acute lymphoblastic leukemia (22 patients, 31."1.56Factors predicting endocrine late effects in childhood cancer survivors from a Japanese hospital. ( Kazukawa, I; Kihara, M; Minagawa, M; Mori, K; Shimazaki, S, 2020)
"Among patients with acute lymphoblastic leukemia (ALL) (n = 314), there were no differences in overall survival (OS) by conditioning regimen."1.56Comparison of reduced-intensity/toxicity conditioning regimens for umbilical cord blood transplantation for lymphoid malignancies. ( Atsuta, Y; Fukuda, T; Imahashi, N; Inamoto, Y; Ishikawa, J; Kako, S; Kanda, J; Kimura, T; Kobayashi, H; Kondo, E; Kozai, Y; Matsuoka, KI; Sakai, H; Tanaka, M; Terakura, S; Uchida, N, 2020)
"Patients with primary HLH transplanted 2009-2016 after treosulfan- or melphalan-based conditioning regimens were analyzed in a retrospective multicenter study for survival, engraftment, chimerism, and adverse events."1.56Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning. ( Albert, MH; Bader, P; Beier, R; Burkhardt, B; Chada, M; Ehl, S; Greil, J; Gruhn, B; Janka, G; Kühl, JS; Lang, P; Lehmberg, K; Meisel, R; Müller, I; Ozga, AK; Schlegel, PG; Schulz, A; Seidel, M; Speckmann, C; Sykora, KW; Wawer, A; Wössmann, W; Wustrau, K, 2020)
"We analyzed 257 patients with acute myeloid leukemia (AML) who received allogeneic stem cell transplantation (SCT) and fulfilled the following criteria: intermediate- or poor-risk disease by National Comprehensive Cancer Network guidelines (2017, version 3), in first complete remission (CR1) at SCT, received either myeloablative conditioning (MAC; busulfan plus cyclophosphamide or cyclophosphamide plus total body irradiation) or reduced-intensity conditioning (RIC; FluBu2TBI400) peripheral blood SCT from 8/8 matched sibling or unrelated donor, and having bone marrow Wilms tumor gene 1 (WT1) expression results before transplant."1.56Comparison of Myeloablative (CyTBI, BuCy) versus Reduced-Intensity (FluBu2TBI400) Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia Patients with Pretransplant Low WT1 Expression. ( Cho, BS; Cho, SG; Eom, KS; Jeon, YW; Kim, DW; Kim, HJ; Kim, YJ; Lee, JW; Lee, S; Lee, SE; Min, CK; Min, GJ; Park, S; Park, SS; Shin, SH; Yahng, SA; Yoon, JH, 2020)
"Factors independently associated with delayed puberty were extensive chronic GVHD (P = ."1.56Pubertal outcomes of children transplanted with allogeneic stem cells after myeloablative total body irradiation or busulfan: Influence of age and sex is confirmed, while a role of chronic graft-versus-host disease in delayed puberty onset is revealed. ( Dalle, JH; Lebon Labich, B; Leheup, B; Pochon, C; Weinhard, S; Wiedemann, A, 2020)
" Prophylactic T cell depletion via antithymocyte globulin (ATG) during ASCT conditioning is one of the standards of care for GVHD prophylaxis, although the optimal dosing strategy is still unclear."1.56Antithymocyte globulin administration in patients with profound lymphopenia receiving a PBSC purine analog/busulfan-based conditioning regimen allograft. ( Bene, MC; Blin, N; Chevallier, P; Debord, C; Dubruille, V; Duquesne, A; Eveillard, M; Garnier, A; Gastinne, T; Guillaume, T; Jullien, M; Le Bourgeois, A; Le Bris, Y; Le Gouill, S; Mahe, B; Moreau, P; Peterlin, P; Tessoulin, B; Touzeau, C; Wuilleme, S, 2020)
"Busulfan is an alkylating agent used in pre-transplant conditioning for patients undergoing hematopoietic stem cell transplantation."1.51A novel drug interaction between busulfan and blinatumomab. ( Lee, J; Oh, A; Patel, P; Quigley, JG; Rondelli, D; Sweiss, K; Ye, R, 2019)
"Busulfan is a major component of chemotherapy conditioning in hematopoietic cell transplantation (HCT)."1.51Retrospective study of the digestive tract mucositis derived from myeloablative and non-myeloablative/reduced-intensity conditionings with busulfan in hematopoietic cell transplantation patient. ( Bezinelli, LM; Carvalho, DLC; Corrêa, L; da Silva, CC; Eduardo, FP; Ferreira, MH; Gobbi, M; Hamerschlak, N; Rosin, FCP, 2019)
"Primary refractory acute myeloid leukemia (AML) is associated with a dismal prognosis."1.51Sequential therapy for patients with primary refractory acute myeloid leukemia: a historical prospective analysis of the German and Israeli experience. ( Amit, O; Avivi, I; Chemnitz, JM; Hallek, M; Holtick, U; Moshe, Y; Ram, R; Scheid, C; Wolf, D, 2019)
"Twenty patients with primary acute myeloid leukemia had been randomized into busulfan/fludarabine and modified busulfan/cyclophosphamide groups."1.48Comparison of Different Conditioning Regimens of Haploidentical Hematopoietic Stem Cell Transplant in Patients With Acute Myeloid Leukemia. ( Fang, X; Jiang, Y; Li, Y; Liu, X; Sui, X; Wang, X; Xu, H; Zhang, L, 2018)
"Only viral infections were significantly increased in the non-TBI group."1.48Long-term outcomes of total body irradiation plus cyclophosphamide versus busulfan plus cyclophosphamide as conditioning regimen for acute lymphoblastic leukemia: a comparative study. ( Anagnostopoulos, A; Apostolou, C; Athanasiadou, A; Batsis, I; Bousiou, Z; Bouziana, S; Chatziioannou, K; Constantinou, V; Douka, V; Gavriilaki, E; Gianouzakos, V; Iskas, M; Lalayanni, C; Mallouri, D; Papathanasiou, M; Sakellari, I; Sotiropoulos, D; Yannaki, E, 2018)
"Alopecia was defined as clinically apparent decreased hair density."1.46Permanent diffuse alopecia after haematopoietic stem cell transplantation in childhood. ( Ball, LM; Bresters, D; Fiocco, M; Louwerens, M; van Doorn, R; Wanders, DCM, 2017)
"Busulfan was administered in four daily divided doses either orally (n = 72) or intravenously (n = 59) with pharmacokinetics on the first-dose and as necessary on subsequent doses to achieve a target area-under-the-concentration-curve (AUC) of 800-1400 μmol*min/L per dose."1.43Therapeutic drug monitoring for either oral or intravenous busulfan when combined with pre- and post-transplantation cyclophosphamide. ( Ambinder, RF; Bolaños-Meade, J; Borrello, I; Brodsky, RA; Durakovic, N; Fuchs, EJ; Gladstone, DE; Huff, CA; Jones, RJ; Kanakry, CG; Kasamon, YL; Lombardi, LR; Luznik, L; Matsui, W; Rosner, GL; Swinnen, LJ; Zahurak, M, 2016)
"Animal disease models have been criticized for lack of resemblance to human illnesses, hampering transfer of knowledge from preclinical research to clinical medicine."1.43A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation. ( Elezkurtaj, S; Kalupa, M; Penack, O; Riesner, K; Shi, Y, 2016)
" Moreover, it appears to be safe with a low NRM rate among high-risk patients."1.43The efficacy and safety of a new reduced-toxicity conditioning with 4 days of once-daily 100 mg/m(2) intravenous busulfan associated with fludarabine and antithymocyte globulins prior to allogeneic stem cell transplantation in patients with high-risk myel ( Blaise, D; Calmels, B; Castagna, L; Chabannon, C; Crocchiolo, R; Devillier, R; El-Cheikh, J; Faucher, C; Furst, S; Granata, A; Harbi, S; Lemarie, C; Vey, N; Wanquet, A; Weiller, PJ, 2016)
"Thirty-four patients had thalassemia major and 4 had SCA."1.43Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies Using a Tailored Busulfan-Based Conditioning Regimen: Single-Center Experience. ( Ben-Arush, M; Elhasid, R; Khalil, A; Rowe, JM; Zaidman, I, 2016)
"A total of 30 patients with hematologic malignancies (8 cases of AML, 17 AML, 2 MDS and 3 Mix-AL) received related haploidentical and unrelated HLA-mismatched allo-HSCT combined with related haploidentical bone marrow infusion."1.43[Two Kinds of HLA-mismatched Allogeneic Hematopoictic Stem Cell Transplantation for Treatment of Hematologic Malignancies]. ( Gao, ZY; Li, WD; Lu, DP; Lu, DY; Yu, XJ, 2016)
"Relapsed or refractory Hodgkin lymphoma (advanced HL) still remains a therapeutic challenge."1.43Busulfan-based reduced intensity conditioning regimens for haploidentical transplantation in relapsed/refractory Hodgkin lymphoma: Spanish multicenter experience. ( Balsalobre, P; Bento, L; Buño, I; Castilla-Llorente, C; Díez-Martín, JL; Ferrá, C; Figuera, A; Gayoso, J; Heras, I; Herrera, P; Kwon, M; López-Corral, L; Montesinos, P; Pascual, C; Pascual, MJ; Piñana, JL; Serrano, D; Zabalza, A, 2016)
"busulfan (Bu) has been shown to be highly effective as a pretransplant conditioning regimen in acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and myelodysplastic syndrome (MDS)."1.43Long-Term Outcomes after Treatment with Clofarabine ± Fludarabine with Once-Daily Intravenous Busulfan as Pretransplant Conditioning Therapy for Advanced Myeloid Leukemia and Myelodysplastic Syndrome. ( Alatrash, G; Alousi, AM; Andersson, BS; Champlin, RE; Chen, J; de Lima, M; Fox, PS; Garber, HR; Hosing, C; Janbey, S; Jones, RB; Kebriaei, P; Ning, J; Popat, U; Rondon, G; Shpall, EJ; Thall, PF; Valdez, BC; Worth, LL, 2016)
"Cataract was prospectively assessed by serial slip lamp tests in 271 patients included in the Leucémie Enfants Adolescents (LEA) programme, the French cohort of childhood leukaemia survivors."1.42Incidence and risk factors for cataract after haematopoietic stem cell transplantation for childhood leukaemia: an LEA study. ( Auquier, P; Barlogis, V; Berbis, J; Bertrand, Y; Chastagner, P; Contet, A; Galambrun, C; Horwitz, M; Kanold, J; Michel, G; Oudin, C; Plantaz, D; Poiree, M; Sirvent, N; Villes, V, 2015)
" Pharmacokinetic treatment with targeted intravenous busulfan combined with fludarabine (BuFlu) was developed as a preparative regimen for acute leukemia and myelodysplasia."1.42Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma. ( Anasetti, C; Ayala, E; Figueroa, J; Kharfan-Dabaja, MA; Kim, J; Locke, F; Nishihori, T; Perkins, J; Riches, M; Yue, B, 2015)
" We aimed this retrospective study for comparison of weight- and age-based dosing in terms of clinical outcomes such as time to engraftment, early complications, EFS, OS, and toxicity profiles in children receiving iv Bu."1.42Clinical comparison of weight- and age-based strategy of dose administration in children receiving intravenous busulfan for hematopoietic stem cell transplantation. ( Avci, Z; Azik, F; Gürlek Gökçebay, D; Isik, P; Kara, A; Ozbek, N; Tavil, B; Tunc, B, 2015)
" In conclusion, once-daily administration of ivBu has a stable pharmacokinetic profile, and was safely performed in Japanese patients."1.42Pharmacokinetics study of once-daily intravenous busulfan in conditioning regimens for hematopoietic stem cell transplantation. ( Akahoshi, Y; Ashizawa, M; Ishihara, Y; Kako, S; Kanda, J; Kanda, Y; Kawamura, K; Kikuchi, M; Kimura, S; Matsumoto, K; Morita, K; Nakano, H; Nakasone, H; Nishida, J; Oshima, K; Sakamoto, K; Sato, M; Tanaka, Y; Tanihara, A; Terasako-Saito, K; Ugai, T; Wada, H; Yamasaki, R; Yamazaki, R, 2015)
" This regimen was associated with durable donor engraftment and relatively low rates of regimen related toxicity (RRT); future alemtuzumab pharmacokinetic studies may improve outcomes, by allowing targeted alemtuzumab clearance to reduce graft rejection and promote more rapid immune reconstitution."1.42Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. ( Abdel-Azim, H; Crooks, GM; Kapoor, N; Khazal, S; Kohn, DB; Mahadeo, KM; Shah, AJ; Zhao, Q, 2015)
"Pediatric patients with acute myeloid leukemia (AML) mainly receive myeloablative conditioning regimens based on busulfan (BU) or total body irradiation (TBI) before allogeneic hematopoietic cell transplantation (allo-HCT); however, the optimal conditioning regimen remains unclear."1.42Comparison of Outcomes for Pediatric Patients With Acute Myeloid Leukemia in Remission and Undergoing Allogeneic Hematopoietic Cell Transplantation With Myeloablative Conditioning Regimens Based on Either Intravenous Busulfan or Total Body Irradiation: A ( Adachi, S; Atsuta, Y; Goto, H; Inagaki, J; Inoue, M; Ishida, H; Kato, K; Kato, M; Kawano, Y; Koh, K; Kudo, K; Miyamura, T; Ogawa, A; Sawada, A; Taga, T; Terui, K; Tomizawa, D; Yamashita, T, 2015)
"A population pharmacokinetic (PPK) analysis was conducted to describe the influence of GSTA1 polymorphisms on intravenous busulfan in adults undergoing allogeneic hematopoietic stem cell transplantation."1.42Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation. ( Choi, B; Han, N; Ji, E; Kim, IW; Kim, MG; Kim, T; Oh, JM; Park, S, 2015)
"Intravenous (IV) busulfan (Bu) combined with therapeutic drug monitoring-guided dosing is associated with better event-free survival (EFS), lower transplant-related mortality."1.40Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation. ( Ansari, M; Bittencourt, H; Champagne, MA; Desjean, C; Duval, M; Krajinovic, M; Mezziani, S; Peters, C; Rezgui, MA; Théoret, Y; Vachon, MF, 2014)
" Our data indicate that Flu (160 mg/m(2)) with targeted myeloablative Bu (90 mg·h/L) is less toxic than and equally effective as BuCy (Mel) in patients with similar indications for allo-HCT."1.40Fludarabine and exposure-targeted busulfan compares favorably with busulfan/cyclophosphamide-based regimens in pediatric hematopoietic cell transplantation: maintaining efficacy with less toxicity. ( Bartelink, IH; Bierings, MB; Boelens, JJ; de Wildt, A; Gerhardt, CE; Lindemans, CA; van Maarseveen, EM; van Reij, EM; Versluys, B, 2014)
" In an effort to minimize these adverse effects, we conducted bone marrow transplantation (BMT) from unrelated volunteer donors using a conditioning regimen without BU or TBI."1.40Fludarabine, cytarabine, granulocyte colony-stimulating factor and melphalan (FALG with L-PAM) as a reduced toxicity conditioning regimen in children with acute leukemia. ( Kato, K; Matsumoto, K; Matsuyama, T; Yoshida, N, 2014)
" The FB3-ATG2 regimen is safe and efficient in both lymphoid and myeloid disorders."1.40Feasibility of the fludarabine busulfan 3 days and ATG 2 days reduced toxicity conditioning in 51 allogeneic hematopoietic stem cell transplantation: a single-center experience. ( Chantepie, SP; Gac, AC; Reman, O, 2014)
"For patients with mucopolysaccharidosis type IH (MPS1-H; Hurler syndrome), early allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of choice."1.40Unrelated CD3/CD19-depleted peripheral stem cell transplantation for Hurler syndrome. ( Benesch, M; Brunner-Krainz, M; Lackner, H; Paschke, E; Plecko, B; Raicht, A; Schwinger, W; Seidel, M; Sovinz, P; Sperl, D; Strenger, V; Urban, C, 2014)
" busulfan dosing (total dose 3."1.39Busulfan dose intensity and outcomes in reduced-intensity allogeneic peripheral blood stem cell transplantation for myelodysplastic syndrome or acute myeloid leukemia. ( Alyea, EP; Antin, JH; Armand, P; Attar, EC; Ballen, KK; Chen, YB; Coughlin, E; Cutler, C; Dey, BR; Ho, VT; Kennedy, KF; Koreth, J; McAfee, SL; Soiffer, RJ; Spitzer, TR, 2013)
"Thirty-eight patients (34 with acute lymphoblastic leukemia and 4 with lymphoblastic lymphoma) were included in the current study."1.38Feasibility of non-TBI conditioning with busulfan and fludarabine for allogeneic stem cell transplantation in lymphoid malignancy. ( Chae, YS; Choi, JY; Kang, BW; Kim, JG; Kim, YK; Lee, SJ; Lee, YJ; Moon, JH; Seo, JW; Shin, HC; Sohn, SK; Suh, JS, 2012)
"We report the results of 11 patients myelofibrosis, who have received a uniform alemtuzumab-based RIC HSCT."1.37Alemtuzumab based reduced intensity conditioning allogeneic haematopoietic stem cell transplantation for myelofibrosis. ( Abdullah, A; Ho, AY; Kenyon, M; Krishnamurthy, P; Lea, N; Lim, ZY; Marsh, J; Mufti, GJ; Nagi, W; Pagliuca, A; Potter, V; Reiff-Zall, L; Tindell, V, 2011)
"Acute kidney injury was defined as doubling serum creatinine from baseline at any time during the first 180 days posttransplant."1.36Frequency, risk factors, and outcome of acute kidney injury following bone marrow transplantation at Dr Shariati Hospital in Tehran. ( Attari, F; Bahar, B; Falaknazi, K; Hakemi, MS; Najafi, I; Saddadi, F, 2010)
"A prevalence of sleep disorders of 26."1.36Association of busulfan and cyclophosphamide conditioning with sleep disorders after hematopoietic stem cell transplantation. ( Astigarraga, CC; Faulhaber, GA; Furlanetto, TW; Moser Filho, HL; Paludo, AP; Silla, LM, 2010)
" Results of clinical outcome of previous studies performed to optimize busulfan and CsA therapy by controlling their pharmacokinetic variability by means of maximum a posteriori (MAP) Bayesian individualization of both drugs are presented."1.35The use of pharmacokinetic models in paediatric onco-haematology: effects on clinical outcome through the examples of busulfan and cyclosporine. ( Bleyzac, N, 2008)
" The responses and adverse events of the 2 groups were assessed."1.34[Efficacy and toxicity of intravenous busulfan-based conditioning before allogeneic peripheral blood stem cell transplantation for leukemia]. ( Li, J; Luo, SK; Peng, AH; Tong, XZ; Xu, DR; Zhang, GC; Zheng, D; Zou, WY, 2007)
"The only radical cure for thalassemia major patients today is the replacement of the defective hematopoietic system by allogeneic stem cell transplantation (allo-SCT)."1.34Allogeneic stem cell transplantation from matched related and unrelated donors in thalassemia major patients using a reduced toxicity fludarabine-based regimen. ( Abdul-Hai, A; Ackerstein, A; Aker, M; Amar, A; Bitan, M; Gesundheit, B; Or, R; Resnick, IB; Samuel, S; Shapira, MY; Slavin, S; Tsirigotis, P, 2007)
"Although chronic lymphocytic leukemia (CLL) remains an incurable disease with standard chemotherapy, the appropriate role and timing of transplantation are unclear."1.33Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced chronic lymphocytic leukemia. ( Alyea, EP; Antin, JH; Brown, JR; Cutler, C; Fisher, DC; Gribben, JG; Ho, V; Kim, HT; Lee, SJ; Li, S; Milford, EL; Ritz, J; Soiffer, RJ; Stephans, K, 2006)
"This study reports on overall and recurrence-free survival (OS and RFS) of 37 consecutive patients with low- and intermediate-grade NHL receiving a related donor allogeneic BMT using a nonradiation-containing preparative regimen."1.32Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma. ( Kiss, TL; Lipton, JH; Meharchand, J; Messner, HA; Panzarella, T; Reddy, V; Schimmer, AD, 2003)
"Busulfan is a common component of pretransplant conditioning but has an erratic and unpredictable bioavailability when administered orally."1.32Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: myeloablation with reduced toxicity. ( Avigdor, A; Ben-Bassat, I; Bielorai, B; Hardan, I; Nagler, A; Shimoni, A; Toren, A; Yeshurun, M, 2003)
"Busulfan was given once daily."1.32Fludarabine and once-daily intravenous busulfan for allogeneic bone marrow transplantation for Chediak-Higashi syndrome. ( Chan, KW; Gomez Almaguer, D; Gordon, N; Mullen, CA; Tran, H; Worth, L, 2003)
"Three patients with myelofibrosis received allogeneic stem cell transplantation after a dose-reduced conditioning regimen of busulphan (8 mg/kg), fludarabine (180 mg/m2) and antithymocyte globulin (4 x 10 mg/kg)."1.31Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia. ( Ayuk, FA; Erttmann, R; Hansen, A; Hessling, J; Kordes, U; Kröger, N; Panse, J; Renges, H; Werner, M; Zabelina, T; Zander, AR, 2002)
"To evaluate the efficacy and toxicity of two different etoposide (VP-16) dosages (30 or 45 mg/kg) in combination with busulfan/cyclophosphamide as conditioning therapy followed by stem cell transplantation in acute myeloid leukemia (AML), 90 patients with AML received either 30 mg/kg (n = 60) or 45 mg/kg (n = 30) etoposide in combination with busulfan (16 mg/kg) and cyclophosphamide (120 mg/kg)."1.31Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia. ( Braumann, D; Colberg, H; del Valle, F; Erttmann, R; Fiedler, W; Finkenstein, F; Holstein, K; Kabisch, H; Kröger, N; Krüger, W; Kuse, R; Mayer, U; Metzner, B; Renges, H; Sonnen, R; Sonnenberg, S; Stute, N; Zabelina, T; Zander, AR, 2000)
" Plasma concentrations of BU at steady state (C(SS)BU) during the dosing interval were measured for each patient."1.30Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation. ( Anasetti, C; Appelbaum, FR; Bensinger, WI; Bowden, R; Bryant, E; Buckner, CD; Chauncey, T; Clift, RA; Deeg, HJ; Doney, KC; Flowers, M; Gooley, T; Hansen, JA; Martin, PJ; McDonald, GB; Nash, R; Petersdorf, EW; Radich, J; Sanders, JE; Schoch, G; Slattery, JT; Soll, E; Stewart, P; Storb, R; Storer, B; Sullivan, KM; Thomas, ED; Witherspoon, RP, 1997)
"Fifty patients with acute myeloid leukemia (AML) or chronic myeloid leukemia (CML) underwent allogeneic bone marrow transplantation between October 1988 and January 1997."1.30Busulfan, cyclophosphamide and total body irradiation as conditioning for allogeneic bone marrow transplantation for acute and chronic myeloid leukemia. ( Goto, S; Hirabayashi, N; Ishii, M; Mitsuma, A; Noda, N; Yuge, M, 1998)
"Diagnoses included acute myelogenous leukemia (n = 20), acute lymphoblastic leukemia (n = 8) and chronic myelogenous leukemia (n = 2)."1.30Allogeneic bone marrow transplantation for childhood leukemia following a busulfan and melphalan preparative regimen. ( Kato, K; Kojima, S; Matsuyama, T, 1998)
"Dyskeratosis congenita is recognized by its dermal lesions and constitutional aplastic anemia in some cases."1.30Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation. ( Alimoghadam, K; Ghahremani, G; Ghavamzadeh, A; Jahani, M; Khodabandeh, A; Nasseri, P, 1999)
"Busulfan dose was 16 mg/kg given over 4 days."1.29Pulmonary complications of bone marrow transplantation: a comparison of total body irradiation and cyclophosphamide to busulfan and cyclophosphamide. ( Czyzewski, EA; Ghalie, R; Hartsell, WF; Kaizer, H, 1995)
" There were seven acute toxic deaths (8%) and in total 15 patients experienced life-threatening or fatal toxicity."1.29Extramedullary toxicity of a conditioning regimen containing busulphan, cyclophosphamide and etoposide in 84 patients undergoing autologous and allogenic bone marrow transplantation. ( Bernstein, E; Brodsky, I; Bulova, S; Crilley, P; Marks, DI; Mullaney, R; Resnick, K; Styler, MJ; Topolsky, D, 1995)
"A 25-year-old woman with AIDS was submitted to HLA-identical allogeneic BMT after cytoablation with busulphan and cyclophosphamide and combined anti-HIV-1 therapy with zidovudine, IFN-alpha 2 and anti-HIV-1-specific T cell clones."1.29Allogeneic bone marrow transplantation combined with multiple anti-HIV-1 treatment in a case of AIDS. ( Arras, M; Boero, R; Carcassi, C; Contu, L; La Nasa, G; Ledda, A; Orrù, S; Pintus, A; Pizzati, A; Vacca, A, 1993)
"This high risk of relapse is not observed when the dose of cyclophosphamide is increased to 200 mg/kg."1.29Allogeneic bone marrow transplantation for children with acute myeloblastic leukemia in first complete remission: impact of conditioning regimen without total-body irradiation--a report from the Société Française de Greffe de Moelle. ( Bernaudin, F; Blaise, D; Bordigoni, P; Esperou-Bourdeau, H; Gluckman, E; Jouet, JP; Michel, G; Pico, JL; Reiffers, J; Thuret, I, 1994)
"Twenty-three patients developed a malignancy 1."1.29Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients. ( Deeg, HJ; Devergie, A; Gluckman, E; Henry-Amar, M; Schoch, G; Socié, G; Storb, R; Sullivan, KM; Witherspoon, RP, 1996)
"Thirty-eight patients had chronic myelogenous leukemia (17 patients chronic phase, 13 patients accelerated phase, eight patients blast phase), 19 patients had acute leukemia (second complete remission or relapse) and eight patients had myelodysplasia."1.29Unrelated allogeneic bone marrow transplantation using high-dose busulfan and cyclophosphamide (BU-CY) for the preparative regimen. ( Avalos, B; Bolwell, B; Copelan, E; Crilley, P; Gajewski, J; Klein, J; Sahebi, F; Territo, M, 1996)
" Alterations in bioavailability (absorption or first pass elimination) or in actual volume of distribution may account for these differences in drug disposition."1.28Busulfan disposition in children. ( Blazar, B; Grochow, LB; Krivit, W; Whitley, CB, 1990)
"Twenty-five consecutive patients with acute myelogenous leukemia (AML) underwent 26 allogeneic bone marrow transplants at Hahnemann University Hospital."1.28Bone marrow transplantation following busulfan and cyclophosphamide for acute myelogenous leukemia. ( Bigler, R; Brodsky, I; Bulova, S; Crilley, P; Topolsky, D, 1990)
"Ninety-nine patients with acute nonlymphocytic leukemia (ANLL) received HLA-identical bone marrow transplants (BMTs) from sibling donors after preparation with high doses of busulfan and cyclophosphamide."1.28Allogeneic bone marrow transplantation after high-dose busulfan and cyclophosphamide in patients with acute nonlymphocytic leukemia. ( Ambinder, RF; Beschorner, WB; Braine, HG; Burns, WH; Geller, RB; Piantadosi, S; Saral, R; Vogelsang, GB; Wingard, JR; Zahurak, M, 1989)
"Five patients with acute myelocytic leukemia (AML) after combined modality therapy for Hodgkin's disease (HD) were treated with cyclophosphamide and busulfan followed by bone marrow transplantation (BMT)."1.27Successful marrow transplantation for acute myelocytic leukemia following therapy for Hodgkin's disease. ( Burns, WH; Geller, RB; Santos, GW; Saral, R; Vogelsang, GB; Wingard, JR; Yeager, AM, 1988)

Research

Studies (731)

TimeframeStudies, this research(%)All Research%
pre-199039 (5.34)18.7374
1990's107 (14.64)18.2507
2000's180 (24.62)29.6817
2010's252 (34.47)24.3611
2020's153 (20.93)2.80

Authors

AuthorsStudies
Inoue, Y2
Nakano, N2
Fuji, S4
Eto, T6
Kawakita, T6
Suehiro, Y1
Miyamoto, T1
Sawayama, Y1
Uchida, N8
Kondo, T5
Kanda, J9
Atsuta, Y19
Fukuda, T19
Yoshimitsu, M1
Kato, K8
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Thompson, JS1
Jennings, CD1
Brown, SA1
Widmer, MB1
Nikoskelainen, J2
Vindeløv, L2
Parkkali, T2
Lenhoff, S2
Sallerfors, B2
Gluckman, E3
Esperou-Bourdeau, H2
Reiffers, J2
Pico, JL2
Thuret, I1
Bernaudin, F3
Jouet, JP2
van der Jagt, RH1
Pari, G1
McDiarmid, SA1
Boisvert, DM1
Huebsch, LB1
Galimberti, M8
Giardini, C6
Gaziev, D2
Erer, B2
Ripalti, M1
Rapa, S1
Le Heup, B1
von Bueltzingloewen, A1
Sommelet, D1
Pierson, M1
Vowels, M3
Chan, LL1
Giri, N1
Russell, S2
Lam-Po-Tang, R1
Paz, HL1
Topolsky, DL1
Coll, WX1
Patchefsky, A1
Plouvier, E1
Lemerle, S1
Mulargia, M1
von Bueltzingsloewen, A2
Belanger, R1
Perreault, C1
Bonny, Y1
Roy, DC1
Lalonde, Y1
Boileau, J1
Kassis, J1
Lavallee, R1
Lacombe, M1
Mrsić, M1
Nemet, D1
Labar, B1
Bogdanić, V1
Radman, I1
Zupancić-Salek, S1
Kovacević-Metelko, J1
Aurer, I1
Maravić, N1
Rassam, SM1
Katz, F1
Chessells, JM1
Morgan, G1
Lum, LG2
de Planque, MM2
Schultz, KR2
Cronin, S2
Dan, ME2
Mohamed, A2
Hussein, M1
Demeocq, F2
Mechinaud-Lacroix, F1
Sadoun, A1
Cornu, G2
Donadieu, J1
Henry-Amar, M1
Devergie, A3
van Tol, MJ1
Gerritsen, EJ1
de Lange, GG1
van Leeuwen, AM1
Jol-van der Zijde, CM1
Oudeman-Gruber, NJ1
de Vries, E1
Radl, J1
Vossen, JM1
Anderson, JE1
Bettoni, C1
Lange, A2
Malicki, J1
Kaczmarek-Kanold, M1
Głuszak, B1
Suchnicki, K1
Daszkiewicz, P1
Ebell, W1
Greinix, HT1
Keil, F1
Brugger, SA1
Reiter, E1
Linkesch, W1
Lechner, K1
Schneider, B1
Dieckmann, KU1
Fischer, G1
Schwarzinger, I1
Haas, O1
Hinterberger, W1
Mannhalter, C1
Geissler, K1
Hocker, P2
Jager, U1
Tang-naitrisorana, Y1
Issaragrisil, S1
Visuthisakchai, S1
Suvatte, V1
Piankijakum, A1
deMagalhaes-Silverman, M1
Bloom, EJ1
Donnenberg, A1
Lister, J1
Pincus, S1
Ball, ED1
Majolino, I2
Laporte, JP1
Brinch, L1
Cook, G1
Lambertenghi-Deliliers, G1
Rozman, C1
Garcia-Conde, J1
Domingo-Albos, A1
Klein, JL2
Belt, P1
Taylor, CA1
Ezzone, SA3
Scholl, MD3
Fisher, J1
Young, D1
Saglio, G1
Scimè, R1
Serra, A1
Cavallaro, AM1
Fiandaca, T1
Vasta, S1
Pampinella, M1
Catania, P1
Indovina, A1
Marcenò, R1
Santoro, A1
Sahebi, F1
Avalos, B3
Klein, J3
Territo, M1
Maiello, A1
Biggs, J1
Moul, J1
Sabol, P1
Downs, K3
Arslan, O1
Akan, H1
Koç, H1
Beksaç, M1
Ilhan, O1
Ozcan, M1
Yalçín, S1
Gürman, G1
Konuk, N1
Uysal, A1
Clift, R2
Barnett, T1
De Prijck, B1
Sainty, D1
Lafage, M1
Camerlo, J1
Penza, SL2
Belt, PS2
Hehmeyer, DM1
Bechtel, TP2
Gallardo, D1
Berlanga, JJ1
Banda, ED1
Ponce, C1
Salar, A1
Alonso, E1
Espanñol, I1
Riu, C1
Grañena, A1
Hernández-Bronchud, M1
Radich, J1
Soll, E1
Flowers, M1
McDonald, GB1
Nash, R1
Petersdorf, EW1
Stewart, P1
Bertz, H1
Potthoff, K1
Lassau, N1
Leclère, J1
Auperin, A1
Hartmann, O1
Valteau-Couanet, D1
Benhamou, E1
Bosq, J1
Ibrahim, A1
Girinski, T1
Roche, A1
Grigg, A1
Harun, MH1
Pugh, WC1
Amin, K1
Mirza, N1
Seong, D1
Hester, J1
Cabanillas, F1
Chattergoon, DS1
Saunders, EF1
Calderwood, S1
Doyle, J1
Freedman, MH1
Koren, G1
Matsuoka, S1
Ishida, A1
Wakui, M1
Watanabe, R1
Moriki, T1
Ikeda, Y1
Hirabayashi, N2
Essell, JH2
Schroeder, MT1
Harman, GS2
Halvorson, R1
Lew, V1
Snyder, M1
Lewis, SK1
Allerton, JP1
Thompson, JM3
Goto, S1
Ishii, M1
Yuge, M1
Mitsuma, A1
Noda, N1
Bonini, A2
Rosti, G2
Testoni, N1
Remiddi, C1
Mangianti, S1
Campanini, E1
Zuffa, E1
Tura, S2
Kojima, S1
Benni, M1
Gozzetti, A1
Ronconi, S1
Zamagni, E1
Lemoli, RM1
Belardinelli, A1
Minowa, R1
Miyagawa, S1
Fukumoto, T1
Majima, T1
Shimoyama, T1
Fujimura, Y1
Shirai, T1
Simpson, DR1
Nevill, TJ3
Shepherd, JD3
Fung, HC1
Horsman, DE1
Nantel, SH2
Vickars, LM1
Sutherland, HJ1
Toze, CL1
Hogge, DE1
Klingemann, HG3
Naiman, SC1
Barnett, MJ3
Mistrík, M1
Bojtárová, E1
Demecková, E1
Hrubisko, M1
Holománová, D1
Buc, M1
Fehérvízyová, E1
Bátorová, A1
Kusiková, M1
Sakalová, A1
Berger, C1
Stockshläder, M1
Horstmann, M1
Zeller, W1
Schönrock, P1
Kuse, R2
Braumann, D2
Illiger, HJ1
Fiedler, W2
de Witt, M1
Hossfeld, KD1
Weh, HJ1
Alimoghadam, K1
Nasseri, P1
Khodabandeh, A1
Ghahremani, G1
Mellander, L1
Jacobsen, N1
Kulkarni, S1
Powles, RL1
Treleaven, JG1
Singhal, S1
Saso, R1
Horton, C1
Killick, S1
Tait, D1
Ramiah, V1
Rosales, F2
Peylan-Ramu, N1
Cividalli, G3
Varadi, G4
de Medeiros, CR1
Dantas da Cunha, A1
Pasquini, R1
Arns da Cunha, C1
Culbert, S1
Mullen, C1
Roberts, W1
Chan, K1
Carlens, S1
Hägglund, H1
Klaesson, S1
Benvenuto, F1
Figari, O1
Berisso, G1
Frassoni, F1
Watanabe, T1
Kajiume, T1
Abe, T1
Iwai, A1
Iwai, T1
Kuroda, Y1
Khojasteh, HN1
Zakerinia, M1
Ramzi, M1
Haghshenas, M1
Schuler, U1
Freiberg-Richter, J2
Helwig, A2
Plettig, R2
Röllig, C2
Naumann, R1
Kroschinsky, F1
Bostrom, B1
Ramsay, NK1
Sonnenberg, S1
Finkenstein, F1
Mayer, U1
Holstein, K1
Colberg, H1
Sonnen, R1
Metzner, B1
del Valle, F1
Theil, KS1
Tighe, MB1
Young, DC1
Mengarelli, A2
Guglielmi, C2
Perrone, MP1
Gozzer, M1
Cimino, G1
Testi, AM1
Ricci, R1
De Felice, L2
Girelli, G1
Mandelli, F1
Brunstein, CG1
Mcglave, PB1
Ruiz-Argüelles, A1
Cantú, OG1
Jaburg, N1
Löliger, C1
Suenaga, K1
Niiya, H1
Ohnishi, M1
Takeuchi, T1
Miyawaki, S1
Ohnishi, T2
Kanai, S2
Kim, I1
Chang, HM1
Bang, SM1
Byun, JH1
Kim, DJ1
Jenke, A1
Geissler, G1
Lutterbeck, K1
Oelschlagel, U1
Schrum, J1
Hertenstein, B1
Chevret, S1
Johansson, JE1
Ekman, T1
Iori, A1
Romano, A1
Cerretti, R1
Torromeo, C1
Micozzi, A1
Fenu, S1
Donato, V1
Barkholt, L1
Stierner, U1
Huang, L1
Shoji, N1
Ogasawara, T1
Matsubara, H1
Reece, DE2
Glejzer, O1
Sedzimirska, M1
Tomaszewska-Toporska, B1
Tomeczko, J1
Kołodziej, J1
Pacuszko, T1
Was, A1
Bocheńska, J1
Jaźwiec, B1
Klimczak, A1
Biggs, JC3
Atkinson, K3
Dodds, A1
Concannon, AJ1
Tutschka, P1
Bianco, JA1
Singer, JW1
Dalton, W1
Beatty, P1
Fefer, A1
Cullis, JO1
Schwarer, AP1
Hughes, TP1
Hows, JM1
Franklin, I1
Morgenstern, G1
Goldman, JM1
Stevens, M1
Tiedemann, K1
Brown, R1
Geller, RB3
Myers, S1
Devine, S1
Williams, SF1
Park, CL1
O'Toole, K1
Chandler, C1
Topper, RL1
Leisz, MC1
Kawahara, K1
Bianco, J1
Petersen, F1
Archimbaud, E1
Halvorson, RD1
Snyder, MJ1
Johnson, RA1
Rubinsak, JR1
Vogelsang, GB3
Farmer, ER1
Altomonte, V1
Hess, AD3
Emminger, W2
Emminger-Schmidmeier, W2
Haas, OA1
Ambros, P1
Mann, G1
Fink, FM1
Ferstl, G1
Cunningham, I2
Klein, JP3
Vaughan, WP1
Dennison, JD1
Reed, EC1
Klassen, L1
McGuire, TR1
Sanger, WG1
Kumar, PP1
Warkentin, PI1
Gordon, BG1
Bierman, PJ1
Gadner, H1
Durazzi, SM3
Nicolini, G1
Politi, P3
Albertini, F2
Vellodi, A2
Jurges, E1
el-Tumi, M1
Abdul-Ahad, A2
Hobbs, JR3
Vermylen, C1
Philippe, M1
Ninane, J1
Borja, A1
Latinne, D1
Ferrant, A1
Michaux, JL1
Sokal, G1
Baker, BW1
Wilson, CL1
Davis, AL1
Spearing, RL1
Hart, DN1
Heaton, DC1
Beard, ME1
Grochow, LB1
Krivit, W1
Whitley, CB1
Blazar, B1
Bigler, R1
Filocamo, M2
Bartolucci, M1
Kolb, HJ1
Bender-Götze, C1
Walther, U1
Mittermüller, J1
Clemm, C1
Bauchinger, M1
Gerhartz, HH1
Brehm, G1
Ledderose, G1
Fischer, AC2
Piantadosi, S1
Wingard, JR2
Beschorner, WB1
Manenti, F2
Barrett, AJ1
Sobocinski, A1
Horowitz, M1
Bortin, MM1
Di Girolamo, G1
Angrilli, F1
Catinella, V1
Ciancarelli, M1
Dragani, A1
D'Antonio, D1
Palka, G1
Guanciali-Franchi, P1
Iacone, A1
Hugh-Jones, K2
Jones, ST1
Rogers, JR1
Frappaz, D1
Bergerat, JP1
Hervé, P1
Freycon, F1
Engelhard, D1
Brautbar, C2
Weshler, Z1
Weiss, L1
Mumcuoglu, M1
Rachmilewitz, EA1
Centis, F2
Agostinelli, F2
Giorgi, C2
Filippetti, A1
Capriotti, L1
Salvadori, P1
Dardanelli, C1
Barbanti, I1
Cottler-Fox, M1
Torrisi, J1
Cahill, R1
Greenspan, A1
Lynch, M1
Bearman, SI1
Rossi, MC1
De Biagi, M1
Izzi, T1
Delfini, C1
Manna, M1
Ostendorf, P1
Schmidt, H1
Haen, M1
Schüch, K1
Müller, C1
Wernet, P1
Dopfer, H1
Hale, G1
Waldmann, H1
Rachmilewitz, E1
Vowels, MR1
Berdoukas, V1
Lam-Po-Tang, PR1
Ford, D1
Linch, DC1
Burnett, AK1
Inoue, S1
Ginsburg, D1
Smith, BR1
Nathan, DG1
Orkin, SH1
Rappeport, JM1
Williamson, S1
Chambers, JD1
James, DC1
Joshi, R1
Lemmel, EM2
Nouza, K2
Motycka, K1
Soucek, J1

Clinical Trials (66)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Busulfan Plus Cyclophosphamide vs Total Body Irradiation Plus Cyclophosphamide Conditioning Regimen for Standard-risk Acute Lymphocytic Leukemia Undergoing HLA-matched Allogeneic Hematopoietic Stem Cell Transplantation[NCT02670252]Phase 3550 participants (Actual)Interventional2016-01-31Completed
Intensive Conditioning Regimen With Thiotepa Combined With Busulfan, Fludarabine and Cytarabine for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Myeloid Malignancies With Extramedullary Involvement[NCT06111612]50 participants (Anticipated)Observational2024-01-01Not yet recruiting
Decitabine Followed by Bone Marrow Transplant and High-Dose Cyclophosphamide for the Treatment of Relapsed and Refractory Acute Myeloid Neoplasms[NCT01707004]Phase 220 participants (Actual)Interventional2013-05-16Completed
Transplantation of Umbilical Cord Blood in Patients With Hematological Malignancies Using a Treosulfan Based Preparative Regimen[NCT00796068]Phase 2130 participants (Actual)Interventional2009-02-24Completed
Reduced Intensity Conditioning With Fludarabine and Busulfan Versus Fludarabine and Melphalan Before Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Randomised, Single-Center, Phase III Study[NCT05674539]Phase 3200 participants (Anticipated)Interventional2022-12-28Recruiting
A Clinical Study of Low-dose Total Body Irradiation and Fludarabine/Busulfan/Melphalan as a Conditioning Regimen for Secondary Umbilical Cord Blood Transplantation in Patients With Hematological Malignancies Who Relapsed After Allo-HSCT[NCT06125483]38 participants (Anticipated)Interventional2023-11-01Recruiting
Allogeneic Hematopoietic Cell Transplant for Hematological Cancers and Myelodysplastic Syndromes in HIV-Infected Individuals (BMT CTN #0903)[NCT01410344]Phase 220 participants (Actual)Interventional2011-09-30Completed
A Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia (BMT CTN #0901)[NCT01339910]Phase 3272 participants (Actual)Interventional2011-06-30Terminated (stopped due to Accrual terminated as recommended by the data and safety monitoring board.)
Phase I Trial of Haploidentical Natural Killer (NK) Cells in Combination With Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)[NCT03366064]Phase 15 participants (Actual)Interventional2017-11-09Completed
Allogeneic HCT From Donor-sources of Matched-sibling, Matched-unrelated, or Haploidentical-family Donors Using Uniform Conditioning Regimen of Busulfan, Fludarabine, and Antithymocyte Globulin for AML in Remission - an Observational Study[NCT03337568]110 participants (Anticipated)Observational2017-04-01Recruiting
Modified Post-Transplant Cyclophosphamide Combined With DCAG as a Bridge Followed by Busulfan, Fludarabine and Melphalan Based Conditioning Regimen for Children With Juvenile Myelomonocytic Leukemia[NCT03687463]6 participants (Actual)Observational [Patient Registry]2015-04-10Enrolling by invitation
The Therapeutic Window of Busulfan in Children With Haemopoietic Stem Cell Transplantation:A Multicenter Study in China[NCT04786002]500 participants (Anticipated)Observational2020-11-01Recruiting
Polymorphisms and Busulfan Pharmacokinetic Study in Pediatric Transplnatation[NCT01257854]200 participants (Anticipated)Observational2008-02-29Recruiting
A Multicentric, Exploratory, Non-randomised, Non-controlled, Prospective, Open-label Phase II Study Evaluating Safety and Efficacy of IBU, G-CSF and Plerixafor as Stem Cell Mobilization Regimen in Patients Affected by X-CGD[NCT03055247]Phase 23 participants (Anticipated)Interventional2015-11-06Recruiting
Investigation of Novel Targetable Kinases in Steroid-refractory Acute Graft-versus-host Disease[NCT04342442]24 participants (Actual)Observational2017-01-01Completed
Trial Of Double Umbilical Cord Blood Transplantation[NCT00763490]Phase 220 participants (Actual)Interventional2008-12-31Completed
A Phase I/II Feasibility Study of Gene Transfer for Artemis-Deficient Severe Combined Immunodeficiency (ART-SCID) Using a Self-Inactivating Lentiviral Vector (AProArt) to Transduce Autologous CD34 Hematopoietic Cells[NCT03538899]Phase 1/Phase 225 participants (Anticipated)Interventional2018-05-31Recruiting
Trial of Allogeneic BMT for Hematologic Malignancies Using HLA-matched Related or Unrelated Donors With Fludarabine and IV Busulfan as Pre-transplant Conditioning Followed by Post-transplant Immunosuppression With High-dose Cyclophosphamide[NCT00809276]Phase 1/Phase 292 participants (Actual)Interventional2009-05-31Completed
Safety and Efficacy of Ibritumomab Tiuxetan (Zevalin®) in Association With a Fludarabine Based Reduced Conditioning Regimen and Allogenic Stem Cell Support in Chemo-sensitive Relapsed CD20 Positive Aggressive Non-Hodgkin's Lymphoma Patients.[NCT00607854]Phase 231 participants (Actual)Interventional2008-02-29Completed
The Use of Granulocyte Transfusions After Umbilical Cord Blood Transplant for Leukaemia: A Prospective, Non-randomised, Single-centre Study to Evaluate Safety and Immune Reconstitution[NCT05425043]20 participants (Anticipated)Interventional2021-09-14Recruiting
Phase I/II Study Evaluating Safety and Efficacy of Autologous Hematopoietic Stem and Progenitor Cells Genetically Modified With IDUA Lentiviral Vector Encoding for the Human α-L-iduronidase Gene for the Treatment of Patients Affected by Mucopolysaccharido[NCT03488394]Phase 1/Phase 28 participants (Actual)Interventional2018-05-11Active, not recruiting
Sequential Myeloablative Autologous Stem Cell Transplantation Followed by Allogeneic Non-Myeloablative Stem Cell Transplantation for Patients With Poor Risk Lymphomas[NCT01181271]Phase 242 participants (Actual)Interventional2010-08-31Completed
Bortezomib-based Graft-Versus-Host-Disease Prophylaxis After Myeloablative Allogeneic Stem Cell Transplantation for Patients Lacking HLA-matched Related Donors: A Phase 2 Study[NCT01323920]Phase 235 participants (Actual)Interventional2011-05-31Completed
Allogeneic Hematopoietic Cell Transplantation for Patients With Hematologic Disorders Who Are Undergoing Dose-Adjusted Treatment With A Maximally Intensive Busulfex-Based Therapeutic Regimen[NCT00448357]Phase 1/Phase 254 participants (Actual)Interventional2005-10-31Completed
Allogeneic Stem Cell Transplantation With Treosulfan, VP-16 and Cyclophosphamide for Patients With Acute Lymphoblastic Leukemia (ALL) Not Eligible for TBI-containing Conditioning Regimen: A Phase II-study[NCT00682305]Phase 250 participants (Actual)Interventional2007-03-31Completed
A Randomized Study of a New Medical Device for Oral Mucositis (MDOM Trial)[NCT05104268]Phase 1/Phase 2100 participants (Anticipated)Interventional2021-11-30Not yet recruiting
Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic Hematopoietic Stem Cell Transplantation.[NCT06071637]Phase 384 participants (Anticipated)Interventional2023-08-01Recruiting
A Phase II Study Of Allogeneic Transplant For Older Patients With AML In First Morphologic Complete Remission Using A Non-Myeloablative Preparative Regimen[NCT00070135]Phase 2121 participants (Actual)Interventional2004-01-31Completed
Composite Health Assessment Risk Model (CHARM) for Older Adults: Applying Pre-Transplant Comorbidity, Geriatric Assessment, and BioMarkers on Non-Relapse Mortality After Allogeneic Transplant (BMT CTN 1704)[NCT03992352]1,229 participants (Actual)Observational2019-07-19Active, not recruiting
A Phase II Study to Evaluate the Efficacy of Posttransplant Cyclophosphamide for Prevention of Chronic Graft-versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation[NCT01427881]Phase 243 participants (Actual)Interventional2011-09-30Completed
Prospective and Multicentre Evaluation of 3 Different Doses of IV Busulfan Associated With Fludarabine and Thymoglobuline in the Conditioning of Allogeneic Stem Cell Transplantation (SCT) From a Matched Related or Unrelated Donor in Patients With Poor Pro[NCT01985061]Phase 2177 participants (Anticipated)Interventional2013-12-31Recruiting
A Multicenter Phase II Trial of Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine[NCT00987480]Phase 245 participants (Actual)Interventional2009-09-25Completed
PRO#1278: A Phase III Study of Fludarabine and Busulfan Versus Fludarabine, Busulfan and Low Dose Total Body Irradiation in Patients Receiving an Allogeneic Hematopoietic Stem Cell Transplant[NCT01366612]Phase 353 participants (Actual)Interventional2010-06-16Terminated (stopped due to Lack of Accrual)
A Phase II Multicentre, Randomized, Controlled Open-label Study on the Use of Anti-thymocyte Globulin and Rituximab for Immunomodulation of Graft-versus-host Disease in Allogeneic Matched Transplants for Non Malignancies[NCT01810926]Phase 2130 participants (Anticipated)Interventional2011-09-30Recruiting
Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia in Remission Using HLA-matched Sibling Donors, HLA-matched Unrelated Donors, or HLA-mismatched Familial Donors-A Phase 2 Study[NCT01037764]Phase 2100 participants (Anticipated)Interventional2010-01-31Terminated (stopped due to The PI resigned the institute, and the rest investigators at the institute decided to terminate the study.)
Allogeneic Stem Cell Transplantation After Dose-reduced Intensity Conditioning Regimen for Patients With Myelofibrosis With Myeloid Metaplasia (MMM): A Phase II-study[NCT00599547]Phase 2106 participants (Actual)Interventional2002-11-30Completed
Prospective Study of Combined ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT[NCT02677181]Phase 4100 participants (Actual)Interventional2016-01-31Completed
Cyclophosphamide-Busulfan Versus Busulfan-Cyclophosphamide as Conditioning Regimen Before Allogeneic Hematopoietic Stem Cell Transplantation for Leukemia: a Prospective Randomized Study to Assess Liver Toxicity[NCT01779882]72 participants (Actual)Interventional2013-01-31Completed
Busulfan-Fludarabine-Clofarabine With Allogeneic Stem Cell Transplantation for Advanced Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Advanced, Gleevec Refractory Chronic Myeloid Leukemia. A Randomized Phase II Study.[NCT00469014]Phase 272 participants (Actual)Interventional2006-09-30Completed
Evaluation of Treosulfan Pharmacokinetics (PK) in Children Undergoing Allogeneic Haematopoietic Stem Cell Transplantation (HSCT)[NCT02048800]61 participants (Actual)Observational2014-03-31Completed
Unrelated Donor Hematopoietic Stem Cell Transplantation After Nonmyeloablative Conditioning For Patients With Hematological Malignancies[NCT00627666]Phase 252 participants (Anticipated)Interventional2003-01-31Completed
Clinical Phase II Trial to Evaluate the Safety and Efficacy of Treosulfan Based Conditioning Prior to Allogeneic Haematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome (MDS)[NCT01062490]Phase 245 participants (Actual)Interventional2004-11-30Completed
NON-T-CELL DEPLETED HLA-HAPLOIDENTICAL FAMILIAL DONOR HEMATOPOIETIC CELL TRANSPLANTATION AFTER REDUCED INTENSITY CONDITIONING[NCT00521430]30 participants (Anticipated)Interventional2004-04-30Completed
HLA-HAPLOIDENTICAL FAMILIAL DONOR HEMATOPOIETIC CELL TRANSPLANTATION AFTER REDUCED INTENSITY CONDITIONING OF BUSULFAN, FLUDARABINE, AND ANTI-THYMOCYTE GLOBULIN FOR ADULT PATIENTS WITH HEMATOLOGIC MALIGNANCIES AND MYELODYSPLASTIC SYNDROME - A PHASE 2 STUDY[NCT00732316]Phase 254 participants (Actual)Interventional2008-04-30Completed
A Prospective Study Evaluating the Efficacy of the Allogeneic Hematopoietic Cell Transplantation With Antithymocyte Globulin (ATG)-Based Conditioning of Adult Acute Lymphoblastic Leukemia in First / Second Complete Hematologic Remission[NCT02428517]20 participants (Actual)Observational2015-04-30Terminated (stopped due to The PI resigned the institute, and the rest investigators at the institute decided to terminate the study.)
HLA-Haploidentical Hematopoietic Cell Transplantation and Subsequent Donor Natural Killer Cell Infusion in Refractory Acute Leukemia - A Phase 1-2a STUDY[NCT01795378]Phase 1/Phase 256 participants (Actual)Interventional2013-02-28Completed
A Pilot Study of Gemtuzumab Ozogamicin in Combination With Busulfan and Cyclophosphamide (Immunochemotherapy) and Allogeneic Stem Cell Transplantation in Patients With High Risk Acute Myelogenous Leukemia and Myelodysplastic Syndrome[NCT02221310]Phase 225 participants (Anticipated)Interventional2011-12-07Completed
Bone Marrow Transplantation HLA Haploidentical After a Reduced Intensity Conditioning and Prevention of GvHD Based on Post-transplant Cyclophosphamide Administration in Patients With Severe Sickle Cell Disease[NCT03240731]Phase 218 participants (Anticipated)Interventional2017-08-10Active, not recruiting
Randomized Comparison of Once-daily Intravenous Busulfan Plus Cyclophosphamide Versus Fludarabine as a Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation in Leukemia and Myelodysplastic Syndrome[NCT00774280]Phase 3130 participants (Actual)Interventional2002-05-31Completed
Phase I/II Trial of Donor Derived Cytokine Induced Killer (CIK) Cells Infusion for Relapsed Hematologic Malignancy After Haploidentical Stem Cell Transplantation[NCT03821519]Phase 1/Phase 220 participants (Anticipated)Interventional2019-01-13Recruiting
Haploidentical Allogeneic Peripheral Blood Transplantation: Clinical Trial and Laboratory Correlates Examining Checkpoint Immune Regulators' Expression[NCT03480360]Phase 320 participants (Anticipated)Interventional2018-03-28Active, not recruiting
Single Arm Phase II Study of Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia (ALL) in Older Patients Using Fludarabine and Total Body Irradiation (FluTBI) Regimen[NCT01991457]Phase 219 participants (Actual)Interventional2013-08-27Completed
Transplantation of Ex-vivo Expanded Human Cord Blood Hematopoietic Stem Cells Expanded: Evaluation of Hematopoietic and Immunologic Reconstitution After a Reduced-intensity Conditioning Regimen[NCT01034449]Phase 216 participants (Actual)Interventional2010-02-28Completed
Intrabone Infusion of Cord Blood Hemopoietic Stem Cells in Adult Patients With High Risk Haematological Malignancies.[NCT00886522]Phase 223 participants (Actual)Interventional2009-04-30Completed
The Study of New RIC Regimen of BuFlu in Older or Intolerable Patients With Hematologic Malignant Diseases[NCT01828619]60 participants (Anticipated)Observational2013-02-28Enrolling by invitation
[NCT00000603]Phase 20 participants Interventional1996-09-30Completed
Single Arm, Open Label, Phase I Study for Dose and Schedule Finding of Decitabine in Patients With Higher-risk MDS and MDS/AML Receiving Allogeneic Stem Cell Transplantation[NCT01277484]Phase 119 participants (Actual)Interventional2011-01-31Active, not recruiting
Allogeneic Stem Cell Transplantation With Alternative Donor in Treatment of Hematologic Malignancy[NCT02487069]876 participants (Actual)Interventional2015-06-30Completed
Phase II Trial of Fludarabine Combined With Intravenous Treosulfan and Allogeneic Hematopoietic Stem-cell Transplantation in Patients With Chemo-refractory or Previously Untreated Acute Myeloid Leukemia and Myelodysplastic Syndrome.[NCT00491634]Phase 224 participants (Anticipated)Interventional2007-06-30Completed
Safety and Efficacy of a Strategy of Allogeneic Hematopoietic Stem Cell Transplantation After Reduced-intensity Conditioning for Chemosensitive Relapsed Follicular Lymphoma[NCT01208896]Phase 232 participants (Actual)Interventional2011-02-03Completed
PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia[NCT00494897]Phase 4374 participants (Actual)Interventional1996-06-30Completed
A National, Open-Label, Multicenter, Randomized, Comparative Phase III Study of Induction Treatment With VBMCP-VBAD/Velcade Versus Thalidomide / Dexamethasone Versus Velcade / Thalidomide / Dexamethasone Followed by High Dose Intensive Therapy With Autolo[NCT00461747]Phase 3390 participants (Anticipated)Interventional2006-03-31Completed
Validating Ultrasound Biomarkers for Hepatic Sinusoidal Obstruction Syndrome in Pediatric Hematopoietic Cell Transplant Patients[NCT03963999]Phase 40 participants (Actual)Interventional2020-04-01Withdrawn (stopped due to We did not receive grant funding. We will reapply in June of 2020)
Usefulness of Liver Stiffness Measurement in Predicting Hepatic Veno-Occlusive Disease Development in Patients Who Undergo HSCT: a Multicentric Prospective Study[NCT03426358]1,101 participants (Actual)Interventional2015-04-28Completed
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Chronic Phase CML[NCT00001144]Phase 250 participants Interventional1999-10-31Completed
A Phase II Study of Pevonedistat (MLN4924, TAK924) and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission Acute Myelogenous Leukemia[NCT03709576]Phase 23 participants (Actual)Interventional2018-07-18Terminated (stopped due to Funding pulled)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cumulative Incidence of Chronic GVHD According to BMTCTN

Will be summarized with a proportion and a 95% confidence interval. (NCT01707004)
Timeframe: Up to 1 year

Interventionpercentage (Number)
Decitabine + Bone Marrow Transplant40.7

Cumulative Incidence of Grade III-IV Acute GVHD

Determined by the standard bone marrow transplant (BMT) Clinical Trials Network criteria (BMTCTN). Will be analyzed using KM method, a Graft versus Host Disease (GVHD) grade III-IV will be obtained from the KM estimates along with 95% confidence intervals. (NCT01707004)
Timeframe: Day 100

Interventionpercentage of participants (Number)
Decitabine + Bone Marrow Transplant27.8

Number of Participants With Complete Remission After Transplantation

(NCT01707004)
Timeframe: Up to 1 year

InterventionParticipants (Count of Participants)
Decitabine + Bone Marrow Transplant14

Number of Participants With Primary Graft Failure

Defined as less than 5% donor chimerism in the cluster of differentiation (CD)3 and CD33 selected cell populations at any time after transplantation. Will be analyzed using KM method. (NCT01707004)
Timeframe: Day 30

InterventionParticipants (Count of Participants)
Decitabine + Bone Marrow Transplant0

Overall Survival (OS)

Will be analyzed using Kaplan-Meier (KM) method, and OS will be obtained from the KM estimates along with 95% confidence intervals. (NCT01707004)
Timeframe: Day 100

Interventionpercentage of participants (Number)
Decitabine + Bone Marrow Transplant64.7

Percentage of Participants With Platelet Recovery by Day 30

Platelet recovery is defined as the first day of a platelet count greater than 20,000/mm^3 with no platelet transfusions. Will be summarized with mean and standard deviation or median and interquartile range, and the change will be tested using a one-sample paired t-test at a two-tailed significance level of 0.05. (NCT01707004)
Timeframe: Up to day 30

Interventionpercentage with plt engraftment, day 30 (Number)
Decitabine + Bone Marrow Transplant58

Progression Free Survival

(NCT01707004)
Timeframe: Up to 1 year

Interventiondays (Median)
Decitabine + Bone Marrow Transplant141

Time to Neutrophil Recovery

Defined as achieving an absolute neutrophil count (ANC) greater than or equal to 500/ul for three consecutive measurements on different days. Will be summarized with mean and standard deviation or median and interquartile range, and the change will be tested using a one-sample paired t-test at a two-tailed significance level of 0.05. (NCT01707004)
Timeframe: Up to 1 year

Interventiondays (Mean)
Decitabine + Bone Marrow Transplant16

Duration (Days) Until Participants Obtained Platelet Engraftment

Summarized using a range and median of measure in days until participants reached platelet engraftment. Platelet engraftment was defined as the first of 7 consecutive days when the platelet count exceeded 20 x 109/L (untransfused). (NCT00796068)
Timeframe: At 6 months

Interventiondays (Median)
Arm I (Low Risk for Graft Failure)31
Arm II (High Risk for Graft Failure)31

Incidence of Acute or Chronic Graft-versus-host Disease (GVHD)

Overall GVHD is determined based on the organ stage, response to treatment and whether GVHD was a major cause of death. Chronic GVHD will be defined according to the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Described as mild, moderate, or severe as graded according to the attached Organ Scoring Sheet. Symptoms consistent with both chronic and acute GVHD occurring after day 100 will be considered overlap chronic GVHD syndrome. (NCT00796068)
Timeframe: At 1 year

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)7
Arm II (High Risk for Graft Failure)6

Incidence of Clinically Significant Infections

Collected and graded according to the modified National Cancer Institute Common Toxicity Criteria. (NCT00796068)
Timeframe: At 6 months

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)53
Arm II (High Risk for Graft Failure)61

Incidence of Relapse or Disease Progression

Cumulative incidence estimates using non-relapse mortality as competitive event. (NCT00796068)
Timeframe: Up to 2 years

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)17
Arm II (High Risk for Graft Failure)11

Non-relapse Mortality

Death of any cause other than relapse or disease progression was considered. (NCT00796068)
Timeframe: Up to 2 years

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)8
Arm II (High Risk for Graft Failure)10

Number of Participants Surviving by 1 Year

Overall survival was measured from the first day of CBT infusion until death from any cause. (NCT00796068)
Timeframe: At 1 year

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)51
Arm II (High Risk for Graft Failure)47

Number of Participants Surviving up to 2 Years Without Disease Progression

Progression-free survival is the time interval from start of treatment to documented evidence of disease progression. Disease progression was defined by European LeukemiaNet 2017 criteria and International Working Group (IWG) within 3 years of transplant. (NCT00796068)
Timeframe: Up to 2 years

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)37
Arm II (High Risk for Graft Failure)41

Number of Participants With Acute Graft-versus-host Disease (GVHD) Grade II-IV by Day 100

Grade I GVHD is characterized as mild disease, grade II GVHD as moderate, grade III as severe, and grade IV life-threatening. Diagnosing and grading acute GVHD is based on clinical findings (the organ stage, response to treatment and whether GVHD was a major cause of death) and frequently varies between transplant centers and independent reviewers. (NCT00796068)
Timeframe: Day 100

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)36
Arm II (High Risk for Graft Failure)37

Number of Participants With Graft Failure/Rejection

"Patients will be considered primary graft failure provided they meet any criteria listed below, in the absence of documented disease persistence/recurrence or active bone marrow infection (ex. Cytomegalovirus (CMV)):~i. Absence of 3 consecutive days with neutrophils >500/u1 combined with host CD3+ peripheral blood chimerism ≥50% at day 42 ii. Absence of 3 consecutive days with neutrophils >500/u1 under any circumstances at day 55 iii. Death after day 28 with neutrophil count <100/u1 without any evidence of engraftment (< 5% donor CD3+) iv. Primary autologous count recovery with < 5% donor CD3+ peripheral blood chimerism at count recovery and without relapse" (NCT00796068)
Timeframe: Up to 100 days

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)2
Arm II (High Risk for Graft Failure)5

Number of Participants With Secondary Graft Failure

Secondary graft failure is defined as decline of neutrophil count to <500/ul with loss of donor chimerism after day 55 (NCT00796068)
Timeframe: Up to 2 years

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)0
Arm II (High Risk for Graft Failure)0

Number of Patients With Non-relapse Mortality (NRM)

Defined as death from any cause without sign of disease progression or relapse. Loss to follow up are censored, whereas disease relapse or progression are considered competing risks. (NCT00796068)
Timeframe: At day -200

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)7
Arm II (High Risk for Graft Failure)6

The Number of Participants Alive at Two-years Follow up.

Overall survival of participants after two-years of follow up. (NCT00796068)
Timeframe: Up to 2 years

InterventionParticipants (Count of Participants)
Arm I (Low Risk for Graft Failure)50
Arm II (High Risk for Graft Failure)44

Percentage of Participants With Chronic Graft-Versus-Host Disease (GVHD)

Chronic GVHD is classified per 2005 NIH Consensus Criteria (Filipovich et al. 2005) into categories of severity: none, mild, moderate, and severe. Occurrence of chronic GVHD is defined as the occurrence of mild, moderate, or severe chronic GVHD per this classification. (NCT01410344)
Timeframe: 1 Year Post-transplant

Interventionpercentage of participants (Number)
Allogeneic Transplant17.6

Percentage of Participants With Relapse/Progression

Relapse/Progression is defined as relapse or progression of the primary malignancy. (NCT01410344)
Timeframe: 1 Year Post-transplant

Interventionpercentage of participants (Number)
Allogeneic Transplant29.4

Percentage of Participants Recovering Hematologic Function

Recovery of hematologic function is described by the time to neutrophil and platelet recovery. Time to neutrophil recovery will be the first of three consecutive days of > 500 neutrophils/μL following the expected nadir. Time to platelet engraftment will be described by the date when platelet count is > 20,000/μL for the first of three consecutive labs with no platelet transfusions 7 days prior. (NCT01410344)
Timeframe: Days 28 and 100 Post-transplant

Interventionpercentage of participants (Number)
Day 28 Neutrophil RecoveryDay 100 Platelet Recovery
Allogeneic Transplant100.094.1

Percentage of Participants With Acute Graft-Versus-Host Disease (GVHD)

"Acute GVHD is graded according to the scoring system proposed by Przepiorka et al.1995:~Skin stage:~0: No rash~Rash <25% of body surface area~Rash on 25-50% of body surface area~Rash on > 50% of body surface area~Generalized erythroderma with bullous formation~Liver stage (based on bilirubin level)*:~0: <2 mg/dL 1.2-3 mg/dL 2.3.01-6 mg/dL 3.6.01-15.0 mg/dL 4.>15 mg/dL~GI stage*:~0: No diarrhea or diarrhea <500 mL/day~Diarrhea 500-999 mL/day or persistent nausea with histologic evidence of GVHD~Diarrhea 1000-1499 mL/day~Diarrhea >1500 mL/day~Severe abdominal pain with or without ileus * If multiple etiologies are listed for liver or GI, the organ system is downstaged by 1.~GVHD grade:~0: All organ stages 0 or GVHD not listed as an etiology I: Skin stage 1-2 and liver and GI stage 0 II: Skin stage 3 or liver or GI stage 1 III: Liver stage 2-3 or GI stage 2-4 IV: Skin or liver stage 4" (NCT01410344)
Timeframe: Day 100 Post-transplant

Interventionpercentage of participants (Number)
Grade II-IV Acute GVHDGrade III-IV Acute GVHD
Allogeneic Transplant41.211.8

Percentage of Participants With Non-Relapse Mortality

The events for non-relapse mortality are death due to any cause other than relapse of the underlying malignancy. (NCT01410344)
Timeframe: Day 100, 1 Year, and 2 Years Post-transplant

Interventionpercentage of participants (Number)
Day 1001 Year2 Years
Allogeneic Transplant0.011.818.3

Percentage of Participants With Overall Survival

Overall survival is defined as the time from transplant to death from any cause. (NCT01410344)
Timeframe: Six months, 1 Year, and 2 Years Post-transplant

Interventionpercentage of participants (Number)
6 Months1 Year2 Years
Allogeneic Transplant82.458.850.2

Chimerism

Donor T-cell and myeloid chimerism will be described separately by conditioning regimen intensity (myeloablative or reduced intensity) according to proportions with mixed chimerism (5-95% donor cells out of all), full chimerism (>95% donor cells), or graft rejection (<5% donor cells). (NCT01410344)
Timeframe: Week 4, Day 100, and 6 months Post-transplant

InterventionParticipants (Count of Participants)
Week 472365409Week 472365410Day 10072365410Day 100723654096 Months723654096 Months72365410
Graft RejectionNo Assay ReportedFull ChimerismMixed ChimerismDead at Assessment
Reduced Intensity Allogeneic Transplant4
Myeloablative Allogeneic Transplant1
Myeloablative Allogeneic Transplant3
Myeloablative Allogeneic Transplant4
Reduced Intensity Allogeneic Transplant5
Myeloablative Allogeneic Transplant2
Reduced Intensity Allogeneic Transplant2
Myeloablative Allogeneic Transplant0
Reduced Intensity Allogeneic Transplant0

Number of Participants With Primary Graft Failure

Primary graft failure is defined by lack of neutrophil engraftment. (NCT01339910)
Timeframe: 28 days post-transplant

InterventionParticipants (Count of Participants)
Myeloablative Conditioning Regimen (MAC)1
Reduced Intensity Conditioning (RIC)3

Number of Participants With Secondary Graft Failure

Secondary graft failure is defined by initial neutrophil engraftment followed by subsequent decline in neutrophil counts to less than 500x10^6/liter that is unresponsive to growth factor therapy. (NCT01339910)
Timeframe: 18 months post-transplant

InterventionParticipants (Count of Participants)
Myeloablative Conditioning Regimen (MAC)1
Reduced Intensity Conditioning (RIC)4

Percentage of Participants With Chronic GVHD

Chronic GVHD is classified per 2005 NIH Consensus Criteria (Filipovich et al. 2005) into categories of severity: none, mild, moderate, and severe. Occurrence of chronic GVHD is defined as the occurrence of mild, moderate, or severe chronic GVHD per this classification. (NCT01339910)
Timeframe: 18 months post-transplant

Interventionpercentage (Number)
Myeloablative Conditioning Regimen (MAC)64.0
Reduced Intensity Conditioning (RIC)47.6

Percentage of Participants With Disease Relapse

Disease Relapse is defined as relapse of the primary disease. (NCT01339910)
Timeframe: 18 months post-randomization

Interventionpercentage (Number)
Myeloablative Conditioning Regimen (MAC)13.5
Reduced Intensity Conditioning (RIC)48.3

Percentage of Participants With Overall Survival (OS)

Overall survival is defined as survival of death from any cause. (NCT01339910)
Timeframe: 18 months post-randomization

Interventionpercentage (Number)
Myeloablative Conditioning Regimen (MAC)77.5
Reduced Intensity Conditioning (RIC)67.7

Percentage of Participants With Relapse-Free Survival (RFS)

Relapse-free survival is defined as survival without relapse of the primary disease. (NCT01339910)
Timeframe: 18 months post-randomization

Interventionpercentage (Number)
Myeloablative Conditioning Regimen (MAC)67.8
Reduced Intensity Conditioning (RIC)47.3

Percentage of Participants With Treatment-related Mortality

Treatment-related mortality is defined as death without a previous relapse of the primary disease. (NCT01339910)
Timeframe: 18 months post-randomization

Interventionpercentage (Number)
Myeloablative Conditioning Regimen (MAC)15.8
Reduced Intensity Conditioning (RIC)4.4

Percentage of Participants With Acute Graft Versus Host Disease (GVHD)

"Acute GVHD is graded according to the scoring system proposed by Przepiorka et al.1995:~Skin stage:~0: No rash~Rash <25% of body surface area~Rash on 25-50% of body surface area~Rash on > 50% of body surface area~Generalized erythroderma with bullous formation~Liver stage (based on bilirubin level)*:~0: <2 mg/dL~2-3 mg/dL~3.01-6 mg/dL~6.01-15.0 mg/dL~>15 mg/dL~GI stage*:~0: No diarrhea or diarrhea <500 mL/day~Diarrhea 500-999 mL/day or persistent nausea with histologic evidence of GVHD~Diarrhea 1000-1499 mL/day~Diarrhea >1500 mL/day~Severe abdominal pain with or without ileus * If multiple etiologies are listed for liver or GI, the organ system is downstaged by 1.~GVHD grade:~0: All organ stages 0 or GVHD not listed as an etiology I: Skin stage 1-2 and liver and GI stage 0 II: Skin stage 3 or liver or GI stage 1 III: Liver stage 2-3 or GI stage 2-4 IV: Skin or liver stage 4" (NCT01339910)
Timeframe: Day 100 post-transplant

,
Interventionpercentage (Number)
Grade II-IV Acute GVHDGrade III-IV Acute GVHD
Myeloablative Conditioning Regimen (MAC)44.713.6
Reduced Intensity Conditioning (RIC)31.66.8

Percentage of Participants With Neutrophil and Platelet Engraftment

Neutrophil engraftment is defined as achieving an absolute neutrophil count greater than 500x10^6/liter for 3 consecutive measurements on different days. The first of the 3 days will be designated the day of neutrophil engraftment. Platelet engraftment is defined as achieving platelet counts greater than 20,000/microliter for consecutive measurements over 7 days without requiring platelet transfusions. The first of the 7 days will be designated the day of platelet engraftment. Subjects must not have had platelet transfusions during the preceding 7 days. (NCT01339910)
Timeframe: Days 28 and 60 post-transplant

,
Interventionpercentage (Number)
Neutrophil Engraftment at Day 28Platelet Engraftment at Day 60
Myeloablative Conditioning Regimen (MAC)98.595.5
Reduced Intensity Conditioning (RIC)97.896.2

Number of Participants With Donor Cell Engraftment

Donor cell engraftment will be assessed by donor-recipient chimerism assays. Full donor chimerism is defined as the presence of at least 95% donor cells as a proportion of the total population in the peripheral blood or bone marrow. Graft rejection is defined as the presence of no more than 5% donor cells as a proportion of the total population. Mixed chimerism is defined as the presence of between 5% and 95% donor cells. Mixed or full donor chimerism will be considered evidence of donor engraftment. (NCT01339910)
Timeframe: Days 28 and 100 and 18 months post-transplant

InterventionParticipants (Count of Participants)
Day 2872548419Day 2872548420Day 10072548420Day 1007254841918 Months7254842018 Months72548419
Mixed ChimerismFull Donor ChimerismGraft RejectionDeath Prior to AssessmentUnknown (relapsed or missing assay)
Myeloablative Conditioning Regimen (MAC)86
Reduced Intensity Conditioning (RIC)80
Myeloablative Conditioning Regimen (MAC)9
Reduced Intensity Conditioning (RIC)30
Myeloablative Conditioning Regimen (MAC)1
Myeloablative Conditioning Regimen (MAC)0
Reduced Intensity Conditioning (RIC)0
Myeloablative Conditioning Regimen (MAC)36
Reduced Intensity Conditioning (RIC)22
Myeloablative Conditioning Regimen (MAC)106
Reduced Intensity Conditioning (RIC)86
Myeloablative Conditioning Regimen (MAC)12
Myeloablative Conditioning Regimen (MAC)2
Myeloablative Conditioning Regimen (MAC)6
Reduced Intensity Conditioning (RIC)8
Myeloablative Conditioning Regimen (MAC)71
Reduced Intensity Conditioning (RIC)66
Myeloablative Conditioning Regimen (MAC)4
Reduced Intensity Conditioning (RIC)5
Reduced Intensity Conditioning (RIC)1
Myeloablative Conditioning Regimen (MAC)31
Reduced Intensity Conditioning (RIC)42
Myeloablative Conditioning Regimen (MAC)25
Reduced Intensity Conditioning (RIC)19

Percentage of Participants Alive at 1 Year After Transplant

One-year survival rate after transplant (NCT00763490)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Double Cord Blood Tranplant40

Percentage of Patients Alive at the End of the Trial

Event Free Survival (EFS) was determined. Patients were followed up to 5 years (median time of 2.35 years). (NCT00763490)
Timeframe: 5 Years

Interventionpercentage of patients (Number)
Double Cord Blood Tranplant35

Cumulative Incidence of Neutrophil and Platelet Engraftment

The failure to achieve a neutrophil count > 500/uL or a platelet count >30.0 x 10e9 /L within 35 days of the stem cell infusion will be defined as primary engraftment failure. (NCT00763490)
Timeframe: Day 35

Interventionpercentage of participants (Number)
Cumulative incidence of platlet engraftmentCumulative incidence of neutrophil engraftment
Double Cord Blood Tranplant7389

Incidence of Acute (Grade II-IV) and Chronic Graft-vs-host Disease(GVHD)

"The percentage of patients with acute GVHD (Grade II-IV) was determined at 100 days. Patients were followed up to 5 years and the percentage of patients that developed chronic GVHD at the end of the study was tabulated.~Acute GVHD is staged and graded (grade 0-IV, where grade 0 is no involvement and involvement increases by grade) by the number and extent of organ involvement. Patients can have involvement of three organs: skin (rash/dermatitis), liver (hepatitis/jaundice), and gastrointestinal tract (abdominal pain/diarrhea)." (NCT00763490)
Timeframe: Up to 5 years

Interventionpercentage of patients (Number)
Acute GVHD (Grades II-IV)Chronic GVHD
Double Cord Blood Tranplant4035

To Determine the Optimal Regimen of Post-graft Immunosuppression With High-dose Cy Following Fludarabine, Busulfan, and Transplantation of Fully HLA-matched Bone Marrow That Leads to an Acceptable Incidence of Grades III/IV Acute GVHD

Percentage of participants with grade III-IV acute graft versus host disease (GVHD). GVHD is graded on a combination of skin symptoms (rash), gut symptoms (diarrhea), and liver symptoms (using a lab test called bilirubin). Grades range from I to IV, where I is the least severe and IV is the most severe. (NCT00809276)
Timeframe: 1 year

Interventionpercentage of participants (Number)
BuFlu Transplant15

Cumulative Incidence of Disease Relapse

(NCT01181271)
Timeframe: 2-years after allogeneic transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant17.2

Cumulative Incidence of Extensive Chronic Graft-versus-host-disease

Extensive chronic graft versus-host-disease (GVHD) was defined as GVHD that required systemic immunosuppression. (NCT01181271)
Timeframe: 1-year after allogeneic transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant37.9

Cumulative Incidence of Grades II to IV Acute Graft Versus Host Disease (GVHD)

Grade I GVHD is characterized as mild disease, grade II GVHD as moderate, grade III as severe, and grade IV life-threatening. (NCT01181271)
Timeframe: within 200 days after allogeneic transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant13.8

Cumulative Incidence of Non-relapse Mortality

Non-relapse mortality is defined as participants who die from causes other than their underlying disease relapse, such as infection or graft versus host disease (NCT01181271)
Timeframe: 2-years after allogeneic transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant11.1

Estimated Two Year Overall Survival Rate for All Participants

(NCT01181271)
Timeframe: 2 years

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant83

Estimated Two Year Overall Survival Rate for Participants Undergoing Both Autologous and Allogeneic Transplants

(NCT01181271)
Timeframe: Two-years after Allogeneic Transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant89

Estimated Two Year Overall Survival Rate for Participants Undergoing Only Autologous Transplant

(NCT01181271)
Timeframe: two years

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant69

Estimated Two Year Progression Free Survival Rate for All Participants

(NCT01181271)
Timeframe: 2 years

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant64

Estimated Two Year Progression Free Survival Rate for Participants Undergoing Both Autologous and Allogeneic Transplants

(NCT01181271)
Timeframe: 2 years after allogeneic transplant

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant72

Estimated Two Year Progression Free Survival Rate for Participants Undergoing Only Autologous Transplant

(NCT01181271)
Timeframe: Two Years

Interventionpercentage of participants (Number)
Autologous Then Allogeneic Transplant46

Number of Days After Allogeneic Transplant Until Absolute Neutrophil Count Was Equal to or Greater Than 500/uL

(NCT01181271)
Timeframe: within 28 days after allogeneic transplant

Interventiondays (Median)
Autologous Then Allogeneic Transplant12

Peripheral Blood All-cell Donor Chimerism

Successful donor stem cell engraftment is defined as when ≥ 80% of hematopoietic elements are donor-derived as determined by chimerism assays from peripheral blood at day 100 after non-myeloablative allogeneic stem cell transplantation. (NCT01181271)
Timeframe: 100 days post allogeneic transplant

Interventionpercentage of donor-derived elements (Median)
Autologous Then Allogeneic Transplant95

The Cumulative Incidence of Chronic GVHD Requiring Systemic Immune Suppression up to 1 Year After Stem Cell Infusion

(NCT01323920)
Timeframe: 1 year

InterventionPercentage of participants (Number)
Velcade/Tac/MTX53

The Cumulative Incidence of Grade II-IV Acute GVHD up to Day 100 After Stem Cell Infusion

The primary outcome of this study is the cumulative incidence of grade II-IV acute GVHD up to Day 100 after stem cell infusion. Acute GHVD is graded according to the modified Glucksberg criteria (adapted from Thomas et al., NEJM ,1975, pp. 895-90), which is based on criteria by which the provider classifies acute GVHD per its objective organ staging. Acute GVHD is assessed in weekly standard of care visits post stem cell infusion and is captured in the protocol EDC upon evaluation of clinical notes up to Day 100. Data for acute GVHD organ staging and etiologies are collected in an acute GVHD separate case report form and do not include system organ class, expectedness or attribution. (NCT01323920)
Timeframe: Day 100

InterventionPercentage of participants (Number)
Velcade/Tac/MTX32

The Percentage Donor Engraftment up to Day 30 Post Stem Cell Infusion

To assess the percentage donor engraftment up to day 30 post stem cell infusion, defined as the first of 3 consecutive days tested of documented absolute netrophil count (ANC) >/= 500 cells/u/L (NCT01323920)
Timeframe: Day 30

InterventionPercentage of participants (Number)
Velcade/Tac/MTX94

The Non-relapse Mortality, Progression-free and Overall Survival up to 1 Year After Stem Cell Infusion

Progression free and overall survival by 1 year after stem cell infusion will be assessed using the method of Kaplan and Meier. Progression-free survival will be defined as the time from stem cell infusion to the time of disease progression or death from any cause. Overall survival will be defined as the time from stem cell infusion to the time to death from any cause. Patients will be censored at the time last documented alive. Cumulative incidence and Kaplan-Meier curves will be constructed as appropriate. Progression is defined per clinical presentation, not protocol specified, and vary per disease, e.g. blasts in bone marrow or peripheral blood for AML/MDS; lymphoma + on PET/CT re-staging etc. (NCT01323920)
Timeframe: 1 year

InterventionPercent of participants (Number)
non-relapse mortalityprogression-free survivaloverall survival
Velcade/Tac/MTX8.88584

Capacity of Test Dosing of Busulfan That Would Result in the Desired Area Under the Curve Concentration Exposure of Patients Receiving a Full-dose Busulfan Regimen

Test doses of busulfan were administered and plasma levels were measured to determine a targeted AUC dosing estimate. The capacity is reported as the precision with which these test dose goals predicted the actual 90-hour mean AUC levels.Dose targeting precision was estimated by root mean squared error. (NCT00448357)
Timeframe: Day -15 to Day -11

Interventionpercentage of error (Number)
Dose Level 111.7
Dose Level 24.9
Dose Level 310.2
Dose Level 411.1
Dose Level 515.9

Number of Participants With Dose Limiting Toxicities (DLTs)

Dose limiting toxicity will be defined as any irreversible grade 3 or any grade 4 non-hematologic toxicity that is related to busulfan infusion and not graft vs host disease or late infection after recovery from the initial period of myelosuppression. The maximum tolerated dose (MTD) is defined as the dose with probability of dose limiting toxicity (DLT) of 0.25. The dose of continuous infusion IV busulfan based on blood levels derived from a test dose in conjunction with fludarabine and alemtuzumab plus tacrolimus for GVHD prophylaxis. (NCT00448357)
Timeframe: first 6 weeks or 42 days following stem cell infusion

InterventionDLTs (Number)
Dose Level 11
Dose Level 21
Dose Level 31
Dose Level 42
Dose Level 52

Overall Survival

Percentage of participants alive at 3 years post transplant (NCT00448357)
Timeframe: Three years post-transplant

Interventionpercentage of participants (Number)
Low Busulfan AUC Tertile (5078)28
Intermediate Busulfan AUC Tertile (6372)39
High Busulfan AUC Tertile (7605)55

Three-year Relapse-free Survival (RFS) Rate at the Maximum Tolerated Dose Identified During Phase I of the Trial (Target AUC 6912)

Relapse is defined as new or increased sites of disease or positive one marrow after a complete response (CR). The RFS was calculated as the percentage of patients who were alive and without relapse at 3 years (NCT00448357)
Timeframe: Three years post-transplant

Interventionpercentage of participants (Number)
Low Busulfan AUC Tertile22
Intermediate Busulfan AUC Tertile39
High Busulfan AUC Tertile43

Incidence of DNA Chimerism in Patients Between One Month Post Transplant

Deoxyribonucleic acid (DNA) chimerism is a measure identifying the genetic profiles of the transplant recipient and of the donor and then evaluating the extent of mixture in the recipient's blood, bone marrow, or other tissue. (NCT00448357)
Timeframe: 30 days post transplant

InterventionParticipants (Count of Participants)
Whole blood chimerism-AnyWhole blood chimerism->=95% donorT Cell chimerism-AnyT Cell chimerism>=95% donor
Experimental: GVHD Prophylaxis49474630

Incidence of Graft vs Host Disease in Patients Between One Month and Two Years Post Transplant

"GVHD can be mild, moderate or severe depending on the differences in tissue type between patient and donor. GVHD can be acute or chronic. Its symptoms can include:~Rashes, which include burning and redness, that erupt on the palms or soles and may spread to the trunk and eventually to the entire body~Blistering, causing the exposed skin surface to flake off in severe cases~Nausea, vomiting, abdominal cramps, diarrhea and loss of appetite, which can indicate that the gastrointestinal (digestive) tract is affected~Jaundice, or a yellowing of the skin, which can indicate liver damage~Excessive dryness of the mouth and throat, leading to ulcers~Dryness of the lungs, vagina and other surfaces" (NCT00448357)
Timeframe: 100 days post transplant

,,
InterventionParticipants (Count of Participants)
Acute GVHD grade >=IIAcute GVHD grades III and IVChronic GVHD; intermediate/severe
High Busulfan AUC Tertile1132
Intermediate Busulfan AUC Tertile1046
Low Busulfan AUC Tertile724

2 Year DFS for All Patients

Percentage of participants who were alive and relapse free at 2 years for all patients. The 2 year disease free survival, with 95% confidence interval, was estimated using the Kaplan Meier method. (NCT00070135)
Timeframe: Up to 2 years

Interventionpercentage of participants (Number)
Treatment (Fludarabine, Busulfan, Allogeneic PBSC)42

2 Year Disease Free Survival In Unrelated Donor Recipient Group

"Percentage of participants who were alive and relapse free at 2 years for patients who were matched with an unrelated donor for transplant. The 2 year disease free survival, with 95% confidence interval, was estimated using the Kaplan Meier method.~A relapse is defined as any of the following:~Reappearance of leukemia blasts cells in peripheral blood~>5% blasts in the marrow, not attributable to another cause (e.g., bone marrow regeneration)~If there are no circulating blasts, but the marrow contains 5-20% blasts, a repeat bone marrow ≥ 1 week later with >5% blasts is necessary to meet the criteria for relapse~The development of extramedullary leukemia or leukemic cells in the cerebral spinal fluid" (NCT00070135)
Timeframe: 2 years

Interventionpercentage of participants (Number)
Treatment (Fludarabine, Busulfan, Allogeneic PBSC)40

Non-relapse Mortality (NRM)

Percentage of patients who died due to causes other than relapse (NCT00070135)
Timeframe: Up to 5 years

Interventionpercentage of patients (Number)
Treatment (Fludarabine, Busulfan, Allogeneic PBSC)16

Chronic GVHD Requiring Systemic Immunosuppressive Treatment

Chronic GVHD will be defined by National Institutes of Health (NIH) criteria and requiring systemic treatment. A reduction in the cumulative incidence of GVHD from ~35% to ~15% at 1 year would represent a reasonable goal. A sample size of 42 patients provides 90% power to observe such a difference with one-side 5% type-1 error. (NCT01427881)
Timeframe: At 1 year after transplantation

Interventionpercent of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)16

Disease-free Survival

Disease-free survival will be evaluated as Kaplan-Meier estimates. (NCT01427881)
Timeframe: At 1 year post-transplant

Interventionpercentage of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)73.8

Donor Engraftment

Donor engraftment is defined as the count (percent) of patients with full donor chimerism. Full donor chimerism is defined as at least 95% donor CD3 cells in peripheral blood. (NCT01427881)
Timeframe: At day 28

InterventionParticipants (Count of Participants)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)6

Graft Failure

Descriptive statistics will be used to assess the incidence of primary graft failure and secondary graft failure. Primary graft failure is defined as failure to achieve a sustained neutrophil count of >= 500/uL by >= 28 days post-transplant. Secondary graft failure is defined as the decline in neutrophil count to < 500/uL after achieving engraftment which is unrelated to infection or drug effect and is unresponsive to stimulation by growth factors. (NCT01427881)
Timeframe: By greater than or equal to 28 days post-transplant

Interventionpercentage of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)2

Non-relapse Mortality

Defined as death in the absence of recurrent or progressive malignancy after HCT. Non-relapse morality will be assessed with the use of cumulative incidence plots. This secondary endpoint will be characterized and presented as a cumulative incidence. (NCT01427881)
Timeframe: At 2 years

Interventionpercentage of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)14

Overall Survival

Overall survival will be evaluated as Kaplan-Meier estimates. (NCT01427881)
Timeframe: At 1 year post-transplant

Interventionpercentage of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)75.6

Persistent or Recurrent Malignancy After HCT

Recurrent or progressive malignancy will be assessed with the use of cumulative incidence plots. Recurrent malignancy will be defined by hematologic criteria. Recurrent malignancy will also be defined as any unplanned medical intervention designed to prevent progression of malignant disease in patients who have molecular, cytogenetic or flow-cytometric evidence of malignant cells after transplantation. (NCT01427881)
Timeframe: At 2 years

Interventionpercentage of patients (Number)
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)17

Grades II-IV and III-IV Acute GVHD

Grades II-IV and III-IV GVHD will be assessed with the use of cumulative incidence plots. (NCT01427881)
Timeframe: Through day +100 post-transplant

Interventionpercentage of patients (Number)
Grades II-IV GVHDGrades III-IV GVHD
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)770

Hematologic Recovery

Descriptive statistics will be used to assess the median days of neutrophil and platelet recovery. The day of neutrophil recovery is defined as the first day of three consecutive lab values on different days, after the conditioning regimen-induced nadir of blood counts, that the absolute neutrophil count is > 500/uL. The day of platelet recovery is defined as the first day of three consecutive lab values on different days, after the conditioning regimen-induced nadir of blood counts, that the platelet count is >= 20,000/uL without platelet transfusion support in the seven days prior. (NCT01427881)
Timeframe: Up to day +100

Interventiondays (Median)
Neutrophil EngraftmentPlatelet Engraftment
Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)1914

Disease-free Survival at 3 Years

"Defined as time from date of transplant to relapse, graft rejection or graft failure, or death.~Primary non-engraftment is diagnosed when the participants fails to achieve an ANC >/= 500/ul at any time in the first 28 days post-transplant.~For participants with MDS or AML, relapse will be analyzed as to type and genetic origin of the MDS/leukemic cells. These will be defined by an increasing number of blasts in the marrow over 5% by the presence of circulating peripheral blasts, or by the presence of blasts in any extramedullary site. Cytogenetic analysis of the marrow and/or peripheral blood will also be obtained for the diagnosis of relapse." (NCT00987480)
Timeframe: 3 years

Interventionpercentage of participants (Number)
Chemotherapy-based Cytoreductive Regimen Plus a CD34+ Selected77.8

Overall Survival at 3 Years

Overall Survival is defined as time from date of transplant to event (death from any cause) or last follow-up. (NCT00987480)
Timeframe: 3 years

Interventionpercentage of participants (Number)
Chemotherapy-based Cytoreductive Regimen Plus a CD34+ Selected80

The Incidence of Acute GvHD

(NCT00987480)
Timeframe: 100 days

Interventionpercentage of participants (Number)
Chemotherapy-based Cytoreductive Regimen Plus a CD34+ Selected6.7

The Incidence of Early Transplant Related Mortality

(NCT00987480)
Timeframe: 2 years

InterventionParticipants (Count of Participants)
Chemotherapy-based Cytoreductive Regimen Plus a CD34+ Selected0

To Compare the Relapse Rate at 1 Year of Patients With Myeloid Malignancies Receiving Each Treatment

(NCT01366612)
Timeframe: 1 year

InterventionPercent (Number)
Group 138.9
Group 218.8

Treatment Related Mortality

Number of participants with treatment related mortality (death) within the first 30 days following transplantation. (NCT00469014)
Timeframe: First 30 Days

Interventionparticipants (Number)
Arm 1: Busulfan + Fludarabine (30 mg/m^2) + Clofarabine0
Arm 2: Busulfan + Fludarabine (20 mg/m^2) + Clofarabine0
Arm 3: Busulfan + Fludarabine (10 mg/m^2) + Clofarabine0
Arm 4: Busulfan + Clofarabine0

Number of Subjects Disease-free Survival

Percentage of patients without relapse of disease at 2 years (NCT01991457)
Timeframe: 2 years post-transplant

Interventionpercentage of participants (Number)
Treatment63.2

Reviews

34 reviews available for busulfan and Graft-Versus-Host Disease

ArticleYear
Fixed-dose administration and pharmacokinetically guided adjustment of busulfan dose for patients undergoing hematopoietic stem cell transplantation: a meta-analysis and cost-effectiveness analysis.
    Annals of hematology, 2022, Volume: 101, Issue:3

    Topics: Busulfan; Cost-Benefit Analysis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hum

2022
Allogeneic hematopoietic stem cell transplantation for inherited metabolic disorders.
    International journal of hematology, 2022, Volume: 116, Issue:1

    Topics: Activities of Daily Living; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation

2022
Myeloablative conditioning regimens in adult patients with acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation in complete remission: a systematic review and network meta-analysis.
    Bone marrow transplantation, 2023, Volume: 58, Issue:2

    Topics: Adult; Bayes Theorem; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Tra

2023
Total Body Irradiation Versus Chemotherapy Conditioning in Pediatric Acute Lymphoblastic Leukemia Patients Undergoing Hematopoietic Stem Cell Transplant: A Systematic Review and Meta-Analysis.
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Graft vs Host Disease; Hematopoietic Stem Cell

2023
Association between conditioning intensity and height growth after allogeneic hematopoietic stem cell transplantation in children.
    Cancer medicine, 2023, Volume: 12, Issue:16

    Topics: Bronchiolitis Obliterans Syndrome; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell T

2023
Treosulfan Versus Busulfan-based Conditioning in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-analysis.
    Journal of pediatric hematology/oncology, 2023, 10-01, Volume: 45, Issue:7

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retrospecti

2023
Pharmacogenetic aspects of drug metabolizing enzymes in busulfan based conditioning prior to allogenic hematopoietic stem cell transplantation in children.
    Current drug metabolism, 2014, Volume: 15, Issue:3

    Topics: Alkylating Agents; Busulfan; Child; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Genetic Varia

2014
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Tr

2016
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Tr

2016
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Tr

2016
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Tr

2016
[Treatment of Gaucher disease with allogeneic hematopoietic stem cell transplantation: report of three cases and review of literatures].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2015, Volume: 53, Issue:11

    Topics: Antilymphocyte Serum; Busulfan; Child; Child, Preschool; China; Cyclophosphamide; Cyclosporine; Dise

2015
Busulfan use in hematopoietic stem cell transplantation: pharmacology, dose adjustment, safety and efficacy in adults and children.
    Current drug safety, 2008, Volume: 3, Issue:1

    Topics: Animals; Area Under Curve; Busulfan; Drug Interactions; Graft vs Host Disease; Hematopoietic Stem Ce

2008
Safety of conditioning agents for allogeneic haematopoietic transplantation.
    Expert opinion on drug safety, 2009, Volume: 8, Issue:3

    Topics: Animals; Busulfan; Graft vs Host Disease; Humans; Immunosuppressive Agents; Transplantation Conditio

2009
Cyclophosphamide plus total body irradiation compared with busulfan plus cyclophosphamide as a conditioning regimen prior to hematopoietic stem cell transplantation in patients with leukemia: a systematic review and meta-analysis.
    Hematology/oncology and stem cell therapy, 2011, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; D

2011
Treosulfan-based conditioning before hematopoietic SCT: more than a BU look-alike.
    Bone marrow transplantation, 2012, Volume: 47, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Busulfan; Disease-Free Survival; Graft vs Host Disease; Hematopoi

2012
Do different conditioning regimens really make a difference?
    Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012

    Topics: Adult; Aged; Bone Marrow Transplantation; Busulfan; Graft vs Host Disease; Hematologic Neoplasms; Hu

2012
Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000.
    Blood, 2002, Dec-15, Volume: 100, Issue:13

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodie

2002
Treatment-related mortality and graft-versus-leukemia activity after allogeneic stem cell transplantation for chronic lymphocytic leukemia using intensity-reduced conditioning.
    Leukemia, 2003, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cohort Studies; Disease-Free

2003
[Mini-transplantation from HLA-mismatched donors].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:9

    Topics: Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Graft vs Host Disease; Hematol

2003
[Reduced-intensity stem cell transplantation (RIST) for lymphoproliferative diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:9

    Topics: Busulfan; Cause of Death; Clinical Trials as Topic; Disease-Free Survival; Graft vs Host Disease; He

2003
[Mini-transplantation for solid tumors].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:9

    Topics: Adolescent; Adult; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Clinical Trials as Topic

2003
Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:12

    Topics: Adenoviridae Infections; Adenoviruses, Human; Adolescent; Adult; Aged; Anemia, Aplastic; BK Virus; B

2003
Allogenic bone marrow transplantation: current status and future directions.
    Blood, 1983, Volume: 62, Issue:5

    Topics: Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Cell Separation; Cyclophosphamide; Erythroc

1983
Bone marrow transplantation in acute nonlymphoblastic leukemia.
    Seminars in hematology, 1984, Volume: 21, Issue:1

    Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; C

1984
Conditioning regimens for marrow grafting.
    Seminars in hematology, 1984, Volume: 21, Issue:2

    Topics: Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporins

1984
Destruction of the intestinal mucosa after bone marrow transplantation and graft-versus-host disease.
    Survey and synthesis of pathology research, 1984, Volume: 3, Issue:3

    Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Chronic Disease; Combined Modality Therapy; Cy

1984
Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia.
    Blood, 1994, Dec-15, Volume: 84, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Combined Modalit

1994
[Extramedullary toxicity in bone marrow transplantation using busulfan and cyclophosphamide conditioning].
    Sangre, 1995, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Anemia, Refractory, with Excess of Blasts; Arrhythmias, Cardiac; Bone Marrow Tran

1995
[Endocrinal sequela in bone marrow transplantations during childhood and adolescence].
    Annales de pediatrie, 1993, Volume: 40, Issue:7

    Topics: Adolescent; Age Factors; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Cr

1993
Use of busulfan containing chemotherapy for conditioning patients with leukemia for bone marrow allografting.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Actuarial Analysis; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Cyclophospham

1993
The management of chronic myeloid leukaemia--a case history.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Bone Marrow Transplantation; Busulfan;

1997
The biology and treatment of chronic myelogenous leukemia.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Benzamides; Busulfan; Clinical Trials as Topic; Combined Modality Therapy; Cy

2001
[Allogeneic bone marrow transplantation in myeloid leukemia: chemical conditioning, clinical course and results].
    Acta haematologica Polonica, 1992, Volume: 23, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transpl

1992
Infections and immunodeficiency in bone marrow transplantation.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:5 Suppl

    Topics: Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transplantation; Busulfan; Graft vs Host Di

1988
Clinical studies of ABMT in acute myeloid leukaemia.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cyclophosphamide

1986
[Bone marrow transplantation in pediatric patients: review of progress].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Anemia, Aplastic; Blast Crisis; Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Graft vs

1987

Trials

181 trials available for busulfan and Graft-Versus-Host Disease

ArticleYear
Myeloablative conditioning with thiotepa-busulfan-fludarabine does not improve the outcome of patients transplanted with active leukemia: final results of the GITMO prospective trial GANDALF-01.
    Bone marrow transplantation, 2022, Volume: 57, Issue:6

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Prospect

2022
A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation.
    Bone marrow transplantation, 2022, Volume: 57, Issue:8

    Topics: Bayes Theorem; Busulfan; Clofarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation

2022
Treosulfan compared with reduced-intensity busulfan improves allogeneic hematopoietic cell transplantation outcomes of older acute myeloid leukemia and myelodysplastic syndrome patients: Final analysis of a prospective randomized trial.
    American journal of hematology, 2022, Volume: 97, Issue:8

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, My

2022
Vorinostat Combined with Busulfan, Fludarabine, and Clofarabine Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia: Long-Term Study Outcomes.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:8

    Topics: Acute Disease; Busulfan; Clofarabine; Drug Therapy, Combination; Graft vs Host Disease; Hematopoieti

2022
A myeloablative fractionated busulfan conditioning regimen with post-transplant cyclophosphamide in HLA-matched and haploidentical transplantation: results of a phase II study.
    Haematologica, 2022, 10-01, Volume: 107, Issue:10

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2022
Busulfan Plus Cyclophosphamide Versus Total Body Irradiation Plus Cyclophosphamide for Adults Acute B Lymphoblastic Leukemia: An Open-Label, Multicenter, Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 01-10, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell

2023
Reduced-dose post-transplant cyclophosphamide plus low-dose post-transplant anti-thymocyte globulin as graft-versus-host disease prophylaxis with fludarabine-busulfan-cytarabine conditioning in haploidentical peripheral blood stem cell transplantation: A
    British journal of haematology, 2023, Volume: 200, Issue:2

    Topics: Antilymphocyte Serum; Busulfan; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Hematopoietic S

2023
Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation.
    American journal of hematology, 2023, Volume: 98, Issue:6

    Topics: Acetylcysteine; Behavior Therapy; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Ce

2023
Phase II Study of Myeloablative 7-8/8-Matched Allotransplantation with Post-Transplantation Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:9

    Topics: Adult; Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplanta

2023
Busulfan Plus Fludarabine Compared With Busulfan Plus Cyclophosphamide for AML Undergoing HLA-Haploidentical Hematopoietic Cell Transplantation: A Multicenter Randomized Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 10-10, Volume: 41, Issue:29

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Drug Therapy, Combination; Graft vs Host Diseas

2023
Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

2020
Comparative effectiveness of busulfan/cyclophosphamide versus busulfan/fludarabine myeloablative conditioning for allogeneic hematopoietic cell transplantation in acute myeloid leukemia and myelodysplastic syndrome.
    Hematology/oncology and stem cell therapy, 2020, Volume: 13, Issue:3

    Topics: Adult; Aged; Allografts; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Graft vs Host Di

2020
Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic peripheral stem cell transplantation for adult patients with lymphoid malignancies: a prospective single-arm phase II study.
    Frontiers of medicine, 2021, Volume: 15, Issue:1

    Topics: Adult; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2021
Decitabine induction with myeloablative conditioning and allogeneic hematopoietic stem cell transplantation in high-risk patients with myeloid malignancies is associated with a high rate of infectious complications.
    Leukemia research, 2020, Volume: 96

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; De

2020
Treosulfan-based conditioning is feasible and effective for cord blood recipients: a phase 2 multicenter study.
    Blood advances, 2020, 07-28, Volume: 4, Issue:14

    Topics: Busulfan; Fetal Blood; Graft vs Host Disease; Humans; Middle Aged; Prospective Studies

2020
Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 03-01, Volume: 39, Issue:7

    Topics: Adult; Aged; Amsacrine; Busulfan; Cytarabine; Female; Graft vs Host Disease; Humans; Immunosuppressi

2021
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Cyclosporine;

2017
Dose-Reduced Versus Standard Conditioning Followed by Allogeneic Stem-Cell Transplantation for Patients With Myelodysplastic Syndrome: A Prospective Randomized Phase III Study of the EBMT (RICMAC Trial).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Jul-01, Volume: 35, Issue:19

    Topics: Adult; Busulfan; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Graft vs Host Disease;

2017
A Randomized Study Comparing Stem Cell Transplantation Versus Conventional Therapy for Low- and Intermediate-Risk Myelodysplastic Syndromes Patients.
    Stem cells and development, 2017, 08-01, Volume: 26, Issue:15

    Topics: Adult; Busulfan; Cyclophosphamide; Disease Progression; Factor Analysis, Statistical; Female; Graft

2017
Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Cyclophosph

2017
Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Cyclophosph

2017
Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Cyclophosph

2017
Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Cyclophosph

2017
Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Alemtuzumab; Allografts; Busulfan; Child; Child, Preschool; Disease-Free Survival

2018
Effects of two doses of anti-T lymphocyte globulin-Fresenius given after full-match sibling stem cell transplantation in acute myeloblastic leukemia patients who underwent myeloablative fludarabine/busulfan conditioning.
    Hematology/oncology and stem cell therapy, 2018, Volume: 11, Issue:3

    Topics: Adult; Allografts; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Female; Graft vs Host Dise

2018
Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study.
    Pediatric blood & cancer, 2018, Volume: 65, Issue:7

    Topics: Busulfan; Child; Child, Preschool; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease

2018
Safety and Efficacy of Once-Daily Intravenous Busulfan in Allogeneic Transplantation: A Matched-Pair Analysis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:10

    Topics: Adolescent; Adult; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; Hematologic Neopl

2018
Graft-versus-Host Disease-Free, Relapse-Free Survival after Allogeneic Stem Cell Transplantation for Myelodysplastic Syndrome.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Allografts; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Female;

2019
Renal dysfunction within 90 days of FluBu4 predicts early and late mortality.
    Bone marrow transplantation, 2019, Volume: 54, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Adult; Age Factors; Aged; Allografts; Antineoplastic Combined Chemo

2019
Thiotepa, Busulfan, and Fludarabine Conditioning Regimen in T Cell-Replete HLA-Haploidentical Hematopoietic Stem Cell Transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclosporine; Disease-Free Survival; Female; Graft vs Host Diseas

2019
Myeloablative conditioning using timed-sequential busulfan plus fludarabine in older patients with acute myeloid leukemia: long-term results of a prospective phase II clinical trial.
    Haematologica, 2019, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Fe

2019
Unrelated Donor Peripheral Blood Stem Cell Transplantation for Patients with β-Thalassemia Major Based on a Novel Conditioning Regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:8

    Topics: Acute Disease; Adult; Allografts; Antilymphocyte Serum; beta-Thalassemia; Busulfan; Child; Child, Pr

2019
Thiotepa, Fludarabine, and Busulfan Conditioning Regimen before T Cell-Replete Haploidentical Transplantation with Post-Transplant Cyclophosphamide for Acute Myeloid Leukemia: A Bicentric Experience of 100 Patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:9

    Topics: Adult; Aged; Allografts; Busulfan; Chronic Disease; Cyclophosphamide; Disease-Free Survival; Female;

2019
Phase II study of CD4+-guided pentostatin lymphodepletion and pharmacokinetically targeted busulfan as conditioning for hematopoietic cell allografting.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:7

    Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Busulfan; CD4 Lymphocyte Count; CD4-Positive T-Ly

2013
Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.
    Lancet (London, England), 2014, Feb-01, Volume: 383, Issue:9915

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Busulfan; C

2014
Substitution of cyclophosphamide in the modified BuCy regimen with fludarabine is associated with increased incidence of severe pneumonia: a prospective, randomized study.
    International journal of hematology, 2013, Volume: 98, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; Child;

2013
Hematopoietic stem cell transplantation in children and young adults with secondary myelodysplastic syndrome and acute myelogenous leukemia after aplastic anemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool;

2014
Treosulfan, fludarabine, and 2-Gy total body irradiation followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome and acute myeloid leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic S

2014
Prospective pharmacokinetic study of intravenous busulfan in hematopoietic stem cell transplantation in 25 children.
    Pediatric transplantation, 2014, Volume: 18, Issue:3

    Topics: Adolescent; Area Under Curve; Asian People; Busulfan; Child; Child, Preschool; Female; Gas Chromatog

2014
Donor-derived natural killer cells infused after human leukocyte antigen-haploidentical hematopoietic cell transplantation: a dose-escalation study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Child; Disease Progression; Female; Graft v

2014
Extramedullary relapse following total marrow and lymphoid irradiation in patients undergoing allogeneic hematopoietic cell transplantation.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Blast Crisis; Bone Marrow; Busulfan; Ch

2014
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.
    Leukemia, 2015, Volume: 29, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antilymphocyt

2015
Double umbilical cord blood transplantation after novel myeloablative conditioning using a regimen of fludarabine, busulfan, and total lymphoid irradiation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Busulfan; Child; Child, Preschool; Chronic Disease; Cord Blo

2014
Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases: a prospective multicenter trial.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:12

    Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents, Alkylating; Busulf

2014
Multi-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Nov-01, Volume: 32, Issue:31

    Topics: Adult; Aged; Bayes Theorem; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoietic

2014
90Y-ibritumomab tiuxetan, fludarabine, busulfan and antithymocyte globulin reduced-intensity allogeneic transplant conditioning for patients with advanced and high-risk B-cell lymphomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols;

2015
Nonmyeloablative allogeneic hematopoietic stem cell transplant for the treatment of patients with hematologic malignancies using busulfan, fludarabine, and total body irradiation conditioning is effective in an elderly and infirm population.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents; Busulfan; Cyclosporine; Female; Frail Elderly; Graft vs Host Disease; H

2015
Treosulfan-fludarabine-thiotepa conditioning before allogeneic haemopoietic stem cell transplantation for patients with advanced lympho-proliferative disease. A single centre study.
    Hematological oncology, 2016, Volume: 34, Issue:1

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Disease-Free Survival; Fema

2016
Matched related and unrelated donor hematopoietic stem cell transplantation for DOCK8 deficiency.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Busulfan; Child; Female; Graft Survival; Graft vs Host Disease; Guanine Nucleotid

2015
Phase II Trial of Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide after Reduced-Intensity Busulfan/Fludarabine Conditioning for Hematological Malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Allografts; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Fr

2015
Umbilical cord blood transplantation in adults with advanced hodgkin's disease: high incidence of post-transplant lymphoproliferative disease.
    European journal of haematology, 2016, Volume: 96, Issue:2

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Chronic Disease; Cord Blood Stem Cell Transpla

2016
Reduced-Intensity Conditioning Combined with (188)Rhenium Radioimmunotherapy before Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: The Role of In Vivo T Cell Depletion.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:10

    Topics: Aged; Alemtuzumab; Allografts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens,

2015
Phase II Trial of Tandem High-Dose Chemotherapy with Autologous Stem Cell Transplantation Followed by Reduced-Intensity Allogeneic Stem Cell Transplantation for Patients with High-Risk Lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:9

    Topics: Adult; Aged; Allografts; Antineoplastic Combined Chemotherapy Protocols; Autografts; Busulfan; Disea

2015
A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:11

    Topics: Adult; Bortezomib; Busulfan; Female; Follow-Up Studies; Graft vs Host Disease; Hematologic Neoplasms

2015
Phase I/II Trial of Dose-Escalated Busulfan Delivered by Prolonged Continuous Infusion in Allogeneic Transplant Patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:12

    Topics: Adult; Area Under Curve; Busulfan; Drug Administration Schedule; Female; Graft vs Host Disease; Hema

2015
Phase II Trial of Reduced-Intensity Busulfan/Clofarabine Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Acute Lymphoid Leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:1

    Topics: Adenine Nucleotides; Adult; Aged; Arabinonucleosides; Busulfan; Chronic Disease; Clofarabine; Female

2016
Allogeneic stem cell transplantation after conditioning with treosulfan, etoposide and cyclophosphamide for patients with ALL: a phase II-study on behalf of the German Cooperative Transplant Study Group and ALL Study Group (GMALL).
    Bone marrow transplantation, 2015, Volume: 50, Issue:12

    Topics: Adolescent; Adult; Allografts; Busulfan; Cyclophosphamide; Etoposide; Female; Graft vs Host Disease;

2015
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncolo
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Dec-10, Volume: 33, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Drug Administ

2015
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncolo
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Dec-10, Volume: 33, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Drug Administ

2015
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncolo
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Dec-10, Volume: 33, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Drug Administ

2015
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncolo
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Dec-10, Volume: 33, Issue:35

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Drug Administ

2015
A prospective multicenter study of unrelated bone marrow transplants using a reduced-intensity conditioning regimen with low-dose ATG-F.
    Bone marrow transplantation, 2016, Volume: 51, Issue:3

    Topics: Adult; Aged; Allografts; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Chronic Diseas

2016
Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplantation Cyclophosphamide in Children with Advanced Acute Leukemia with Fludarabine-, Busulfan-, and Melphalan-Based Conditioning.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Allografts; Busulfan; Child; Child, Preschool; Chronic Disease; Cy

2016
Posttransplantation cyclophosphamide for prevention of graft-versus-host disease after HLA-matched mobilized blood cell transplantation.
    Blood, 2016, Mar-17, Volume: 127, Issue:11

    Topics: Adolescent; Adult; Aged; Allografts; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Fr

2016
Phase II Study of Haploidentical Natural Killer Cell Infusion for Treatment of Relapsed or Persistent Myeloid Malignancies Following Allogeneic Hematopoietic Cell Transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Gene Expression; Graft vs Host D

2016
A Phase I Study of Reduced-Intensity Conditioning and Allogeneic Stem Cell Transplantation Followed by Dose Escalation of Targeted Consolidation Immunotherapy with Gemtuzumab Ozogamicin in Children and Adolescents with CD33+ Acute Myeloid Leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Busulfan; Chil

2016
Toxicity and efficacy of busulfan and fludarabine myeloablative conditioning for HLA-identical sibling allogeneic hematopoietic cell transplantation in AML and MDS.
    Bone marrow transplantation, 2016, Volume: 51, Issue:7

    Topics: Adult; Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-

2016
Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience.
    Blood, 2016, 07-21, Volume: 128, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Allografts; Blood Platelets; Busulfan; Child; Child, Preschool; Di

2016
Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study.
    Blood, 2017, 04-20, Volume: 129, Issue:16

    Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow; Busulfan; Child; Child, Preschool; Cyclophosph

2017
Treosulfan/fludarabine as an allogeneic hematopoietic stem cell transplant conditioning regimen for high-risk patients.
    American journal of hematology, 2008, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Aged; Busulfan; Chemical and Drug Induced Liver Injury; Combined Modality Therapy

2008
Transplantation from matched siblings using once-daily intravenous busulfan/fludarabine with thymoglobulin: a myeloablative regimen with low nonrelapse mortality in all but older patients with high-risk disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Antibodies, Monoclonal; Antilymphocyte Serum; Busulfan; Graft

2008
Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Graft Survival; Graft

2008
Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in patients with thalassaemia major.
    British journal of haematology, 2008, Volume: 143, Issue:4

    Topics: Adolescent; Adult; beta-Thalassemia; Busulfan; Child; Child, Preschool; Drug Therapy, Combination; F

2008
Busulfex (i.v. BU) and CY regimen before SCT: Japanese-targeted phase II pharmacokinetics combined study.
    Bone marrow transplantation, 2009, Volume: 43, Issue:8

    Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Diseas

2009
The effect of administration order of BU and CY on toxicity in hematopoietic SCT in humans.
    Bone marrow transplantation, 2009, Volume: 43, Issue:11

    Topics: Adolescent; Adult; Anemia, Aplastic; Busulfan; Cohort Studies; Cyclophosphamide; Follow-Up Studies;

2009
Hematopoietic cell transplantation from an HLA-mismatched familial donor is feasible without ex vivo-T cell depletion after reduced-intensity conditioning with busulfan, fludarabine, and antithymocyte globulin.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Family; Female; Graft vs Host Disease; Hema

2009
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
    Blood, 2009, Dec-17, Volume: 114, Issue:26

    Topics: Adult; Aged; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Male; Middle Ag

2009
Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adult; Aged; Animals; Anti-Infective Agents; Antilymphocyte Serum; Busulfan; Disease Susceptibility;

2009
A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens.
    Blood, 2010, Feb-04, Volume: 115, Issue:5

    Topics: Adolescent; Adult; Busulfan; Child; Cyclophosphamide; Etoposide; Female; Graft vs Host Disease; Hema

2010
Long-term follow-up of an intensified myeloablative conditioning regimen with in vivo T cell depletion followed by allografting in patients with advanced multiple myeloma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2010, Volume: 16, Issue:6

    Topics: Adult; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Disease Progression; Disease-Free Survival;

2010
A pilot study of reduced toxicity conditioning with BU, fludarabine and alemtuzumab before the allogeneic hematopoietic SCT in children and adolescents.
    Bone marrow transplantation, 2011, Volume: 46, Issue:6

    Topics: Adolescent; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neop

2011
Clofarabine ± fludarabine with once daily i.v. busulfan as pretransplant conditioning therapy for advanced myeloid leukemia and MDS.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:6

    Topics: Adenine Nucleotides; Animals; Antilymphocyte Serum; Antineoplastic Agents; Arabinonucleosides; Busul

2011
Phase I trial and pharmacokinetic study of high-dose clofarabine and busulfan and allogeneic stem cell transplantation in adults with high-risk and refractory acute leukemia.
    Leukemia, 2011, Volume: 25, Issue:4

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucle

2011
Higher CD3(+) and CD34(+) cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia.
    Bone marrow transplantation, 2012, Volume: 47, Issue:1

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents; Antigens, CD34; Bone Marrow Transplantation; Bu

2012
Myeloablative reduced-toxicity i.v. busulfan-fludarabine and allogeneic hematopoietic stem cell transplant for patients with acute myeloid leukemia or myelodysplastic syndrome in the sixth through eighth decades of life.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:10

    Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival

2011
Fludarabine and pharmacokinetic-targeted busulfan before allografting for adults with acute lymphoid leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Female; Foll

2011
Clinical effect of reduced-intensity conditioning regimen containing antithymocyte globulin for hematopoietic cell transplantation from unrelated-donors.
    American journal of hematology, 2011, Volume: 86, Issue:5

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Transplantation; Busulfa

2011
Intravenous busulfan-cyclophosphamide as a preparative regimen before allogeneic hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disea

2011
Reduced-toxicity conditioning with treosulfan and fludarabine in allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes: final results of an international prospective phase II trial.
    Haematologica, 2011, Volume: 96, Issue:9

    Topics: Adult; Antineoplastic Agents; Busulfan; Chimerism; Female; Graft vs Host Disease; Hematopoietic Stem

2011
A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:1

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve;

2012
Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or secondary acute myeloid leukemia using a FLAMSA-based high-dose sequential conditioning regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:3

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide;

2012
Degree of mucositis and duration of neutropenia are the major risk factors for early post-transplant febrile neutropenia and severe bacterial infections after reduced-intensity conditioning.
    European journal of haematology, 2012, Volume: 88, Issue:1

    Topics: Adult; Bacterial Infections; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transp

2012
A Phase I study of gemtuzumab ozogamicin (GO) in combination with busulfan and cyclophosphamide (Bu/Cy) and allogeneic stem cell transplantation in children with poor-risk CD33+ AML: a new targeted immunochemotherapy myeloablative conditioning (MAC) regim
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:2

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiat

2012
Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Marrow Transplant

2012
Busulfan, fludarabine, and alemtuzumab as a reduced toxicity regimen for children with malignant and nonmalignant diseases improves engraftment and graft-versus-host disease without delaying immune reconstitution.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:11

    Topics: Adolescent; Alemtuzumab; Antibodies, Monoclonal, Humanized; B-Lymphocytes; Busulfan; Child; Child, P

2012
Phase II study of dose-modified busulfan by real-time targeting in allogeneic hematopoietic stem cell transplantation for myeloid malignancy.
    Cancer science, 2012, Volume: 103, Issue:9

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Female; Graft Survival; Graft vs Host Disease; Hemato

2012
Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan.
    Blood, 2012, Jul-12, Volume: 120, Issue:2

    Topics: Adolescent; Adult; beta-Thalassemia; Busulfan; Child; Child, Preschool; Cohort Studies; Female; Graf

2012
Intravenous BU plus Mel: an effective, chemotherapy-only transplant conditioning regimen in patients with ALL.
    Bone marrow transplantation, 2013, Volume: 48, Issue:1

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Busulfan; Drug Therapy, Combination; Female;

2013
Unmanipulated haploidentical bone marrow transplantation and posttransplantation cyclophosphamide for hematologic malignancies after myeloablative conditioning.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan

2013
Randomized trial of myeloablative conditioning regimens: busulfan plus cyclophosphamide versus busulfan plus fludarabine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-20, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Drug Therapy, Combination; Female; Gastroenteri

2013
Dose intensification of busulfan in the preparative regimen is associated with improved survival: a phase I/II controlled, randomized study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:3

    Topics: Administration, Oral; Aged; Busulfan; Drug Administration Schedule; Female; Graft vs Host Disease; H

2013
Busulfan plus fludarabine as a myeloablative conditioning regimen compared with busulfan plus cyclophosphamide for acute myeloid leukemia in first complete remission undergoing allogeneic hematopoietic stem cell transplantation: a prospective and multicen
    Journal of hematology & oncology, 2013, Feb-08, Volume: 6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Combined Modalit

2013
Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Cells; Busulfan; Child; Cyclophosphamide; Cytogenetic Analysis; Disea

2002
Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes.
    Blood, 2002, Sep-15, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Follow-Up Studies; Gr

2002
Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2002, Volume: 8, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve;

2002
A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation: 500 mg/m(2) as a optimal total dose for conditioning.
    Bone marrow transplantation, 2002, Volume: 30, Issue:12

    Topics: Adult; Age Factors; Busulfan; Child; Cyclophosphamide; Drug Administration Schedule; Drug Carriers;

2002
Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Busulfan; Cyclophosp

2003
Lowered-intensity preparative regimen for allogeneic stem cell transplantation delays acute graft-versus-host disease but does not improve outcome for advanced hematologic malignancy.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2003, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Graft vs Host

2003
Allogeneic stem cell transplantation after a fludarabine/busulfan-based reduced-intensity conditioning in patients with myelodysplastic syndrome or secondary acute myeloid leukemia.
    Annals of hematology, 2003, Volume: 82, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality

2003
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.
    Blood, 2003, Sep-01, Volume: 102, Issue:5

    Topics: Adult; Aged; Busulfan; Cord Blood Stem Cell Transplantation; Fetal Blood; Graft Survival; Graft vs H

2003
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.
    Blood, 2003, Sep-01, Volume: 102, Issue:5

    Topics: Adult; Aged; Busulfan; Cord Blood Stem Cell Transplantation; Fetal Blood; Graft Survival; Graft vs H

2003
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.
    Blood, 2003, Sep-01, Volume: 102, Issue:5

    Topics: Adult; Aged; Busulfan; Cord Blood Stem Cell Transplantation; Fetal Blood; Graft Survival; Graft vs H

2003
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.
    Blood, 2003, Sep-01, Volume: 102, Issue:5

    Topics: Adult; Aged; Busulfan; Cord Blood Stem Cell Transplantation; Fetal Blood; Graft Survival; Graft vs H

2003
Myeloablative intensified conditioning regimen with in vivo T-cell depletion (ATG) followed by allografting in patients with advanced multiple myeloma. A phase I/II study of the German Study-group Multiple Myeloma (DSMM).
    Bone marrow transplantation, 2003, Volume: 31, Issue:11

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Chronic Disease; Cyclophosphamide; Disease-Fre

2003
Allogeneic hematopoietic cell transplantation for paroxysmal nocturnal hemoglobinuria.
    European journal of haematology, 2003, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Antilymphocyte Serum; Busulfan; Drug Therapy, Combination; Female; Graft Survival

2003
Fractionated TBI correlates with less T cell mixed chimerism but increased risk of relapse compared to busulphan in patients with haematological malignancies after allogeneic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Busulfan; Cell Lineage; Child; Child, Preschool; Dose Fractionation, Radiation; F

2003
A new minimally ablative stem cell transplantation procedure in high-risk patients not eligible for nonmyeloablative allogeneic bone marrow transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:6

    Topics: Adult; Busulfan; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cel

2003
Immune reconstitution following reduced-intensity transplantation with cladribine, busulfan, and antithymocyte globulin: serial comparison with conventional myeloablative transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busul

2003
Addition of low-dose busulfan to cyclophosphamide in aplastic anemia patients prior to allogeneic bone marrow transplantation to reduce rejection.
    Bone marrow transplantation, 2004, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; C

2004
Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival.
    Blood, 2004, May-15, Volume: 103, Issue:10

    Topics: Adolescent; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; C

2004
Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies.
    Bone marrow transplantation, 2004, Volume: 33, Issue:9

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfa

2004
Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning.
    Blood, 2004, Sep-15, Volume: 104, Issue:6

    Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo

2004
Graft-versus-myeloma effect following antithymocyte globulin-based reduced intensity conditioning allogeneic stem cell transplantation.
    Bone marrow transplantation, 2004, Volume: 34, Issue:1

    Topics: Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Graft

2004
A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation.
    Bone marrow transplantation, 2004, Volume: 34, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Busulfan; Cyclosporine; Drug

2004
Antileukemic and long-term effects of two regimens with or without TBI in allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia.
    Bone marrow transplantation, 2004, Volume: 34, Issue:8

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cytarabine; Female; Graf

2004
CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens.
    Bone marrow transplantation, 2005, Volume: 35, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmus

2005
Targeted busulfan and cyclophosphamide as compared to busulfan and TBI as preparative regimens for transplantation in patients with advanced MDS or transformation to AML.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Graft Rejectio

2004
High-dose busulfan, cyclophosphamide, and etoposide does not improve outcome of allogeneic stem cell transplantation compared to BuCy2 in patients with acute myeloid leukemia.
    Bone marrow transplantation, 2005, Volume: 35, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of

2005
Modification of the Bu/Cy myeloablative regimen using daily parenteral busulfan: reduced toxicity without the need for pharmacokinetic monitoring.
    Bone marrow transplantation, 2005, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve;

2005
Busulfan/melphalan/antithymocyte globulin followed by unrelated donor cord blood transplantation for treatment of infant leukemia and leukemia in young children: the Cord Blood Transplantation study (COBLT) experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2005, Volume: 11, Issue:8

    Topics: Antilymphocyte Serum; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoc

2005
Comparison of 2 preparative regimens for stem cell transplantation from HLA-matched sibling donors in patients with advanced myelodysplastic syndrome.
    International journal of hematology, 2005, Volume: 82, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Cyclophosphami

2005
Preliminary results of the safety of immunotherapy with gemtuzumab ozogamicin following reduced intensity allogeneic stem cell transplant in children with CD33+ acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 2

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD

2005
Reduced intensity conditioning using intravenous busulfan, fludarabine and rabbit ATG for children with nonmalignant disorders and CML.
    Bone marrow transplantation, 2006, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Animals; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Disease-Free Su

2006
Reduced-toxicity conditioning with treosulfan, fludarabine and ATG as preparative regimen for allogeneic stem cell transplantation (alloSCT) in elderly patients with secondary acute myeloid leukemia (sAML) or myelodysplastic syndrome (MDS).
    Bone marrow transplantation, 2006, Volume: 37, Issue:4

    Topics: Acute Disease; Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bu

2006
Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Cause of Death; Child; Chron

2006
Outcomes of alemtuzumab-based reduced intensity conditioning stem cell transplantation using unrelated donors for myelodysplastic syndromes.
    British journal of haematology, 2006, Volume: 135, Issue:2

    Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo

2006
Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:10

    Topics: Adult; Antilymphocyte Serum; Bone Marrow; Busulfan; CD4 Lymphocyte Count; Combined Modality Therapy;

2006
Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial.
    Bone marrow transplantation, 2007, Volume: 39, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cladri

2007
Adult recipients of matched related donor blood cell transplants given myeloablative regimens including pretransplant antithymocyte globulin have lower mortality related to graft-versus-host disease: a matched pair analysis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2007, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; G

2007
Non-myeloablative hematopoietic stem cell transplantation is of limited value in advanced or refractory acute myeloblastic leukemia. The Mexican experience.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool

2007
The beneficial effect of chronic graft-versus-host disease on the clinical outcome of transplantation with fludarabine/busulfan-based reduced-intensity conditioning for patients with de novo myelodysplastic syndrome.
    International journal of hematology, 2007, Volume: 85, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Busulfan; Chronic Disease; Female; Follow-Up Studies; Graf

2007
Prospective phase II trial to evaluate the complications and kinetics of chimerism induction following allogeneic hematopoietic stem cell transplantation with fludarabine and busulfan.
    American journal of hematology, 2007, Volume: 82, Issue:10

    Topics: Adult; Aged; Busulfan; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Graft vs Hos

2007
Randomized comparison of four-times-daily versus once-daily intravenous busulfan in conditioning therapy for hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2007, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Busulfan; Drug Administration Schedule; Female; Graft Survival; Graft vs Host Dis

2007
Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis.
    Experimental hematology, 2007, Volume: 35, Issue:11

    Topics: Adult; Bone Marrow Examination; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Tra

2007
Safe administration of oral BU twice daily during conditioning for stem cell transplantation in a paediatric population: a comparative study between the standard 4-dose and a 2-dose regimen.
    Bone marrow transplantation, 2008, Volume: 41, Issue:7

    Topics: Administration, Oral; Busulfan; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; G

2008
Myeloablative intravenous busulfan/fludarabine conditioning does not facilitate reliable engraftment of dual umbilical cord blood grafts in adult recipients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:5

    Topics: Adult; Busulfan; Cell Count; Cord Blood Stem Cell Transplantation; Graft Survival; Graft vs Host Dis

2008
Reduced-intensity conditioning allogeneic transplantation from unrelated donors: evaluation of mycophenolate mofetil plus cyclosporin A as graft-versus-host disease prophylaxis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Combined Modality T

2008
In stem cell transplantation, by limiting the morbidity of graft-versus-host disease tolerance to myeloablative conditioning is improved.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Alemtuzumab; Antibiotic Prophylaxis; Antibodies, Monoclonal; Antibodies, Monoclon

2008
Treosulfan and fludarabine low-toxicity conditioning for allogeneic haematopoietic stem cell transplantation in chronic myeloid leukaemia.
    British journal of haematology, 2008, Volume: 142, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Disease-Free Survival; Female; Graft

2008
Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia.
    Blood, 1994, Dec-15, Volume: 84, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Combined Modalit

1994
Combined transplantation of allogeneic bone marrow and CD34+ blood cells.
    Blood, 1995, Oct-01, Volume: 86, Issue:7

    Topics: Adult; Antigens, CD; Antigens, CD34; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclos

1995
Phase II study of busulfan, cyclophosphamide and fractionated total body irradiation as a preparatory regimen for allogeneic bone marrow transplantation in patients with advanced myeloid malignancies.
    Bone marrow transplantation, 1995, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1995
Allogeneic bone marrow transplantation in children with acute myelogenous leukemia in first remission. Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) and the Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO).
    Bone marrow transplantation, 1994, Volume: 13, Issue:6

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therap

1994
A phase I-II study of high-dose thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1994
Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide.
    Blood, 1994, Sep-15, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Bilirubin; Bone Marrow Transplantation; Busulfan; Child; Creatinine; Cyclophospha

1994
A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group.
    Blood, 1994, May-01, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Child, Preschool; C

1994
Effect of pentoxifylline on regimen related toxicity in patients undergoing allogeneic or autologous bone marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 13, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Cyclophospham

1994
Allogeneic marrow transplantation in patients with chronic myeloid leukemia in chronic phase following preparation with busulfan and cyclophosphamide.
    Bone marrow transplantation, 1994, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Cyclopho

1994
Chemotherapy versus allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclop

1993
Allogeneic bone marrow transplantation following a busulfan-based conditioning regimen in young children with acute lymphoblastic leukemia: a Cooperative Study of the Société Française de Greffe de Moelle.
    Bone marrow transplantation, 1995, Volume: 16, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cause of Deat

1995
Allogeneic marrow transplantation for myelodysplastic syndrome with advanced disease morphology: a phase II study of busulfan, cyclophosphamide, and total-body irradiation and analysis of prognostic factors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow

1996
Can busulfan replace fractionated total body irradiation as conditioning regimen for allogeneic bone marrow transplantation in children with acute lymphoblastic leukemia.
    Acta haematologica Polonica, 1995, Volume: 26, Issue:4

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therap

1995
Toxicity of busulfan and cyclophosphamide (BU/CY2) in patients with hematologic malignancies.
    Bone marrow transplantation, 1996, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Busulfan; Combine

1996
Bone marrow engraftment following unrelated donor transplantation utilizing busulfan and cyclophosphamide preparatory chemotherapy.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Ch

1996
Variability in determination of body weight used for dosing busulphan and cyclophosphamide in adult patients: results of an international survey.
    Leukemia & lymphoma, 1997, Volume: 25, Issue:5-6

    Topics: Adult; Body Weight; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Dose-Resp

1997
Allogeneic transplantation for recurrent or refractory non-Hodgkin's lymphoma with poor prognostic features after conditioning with thiotepa, busulfan, and cyclophosphamide: experience in 44 consecutive patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 1997, Volume: 3, Issue:3

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Drug Therapy,

1997
An improved limited sampling method for individualised busulphan dosing in bone marrow transplantation in children.
    Bone marrow transplantation, 1997, Volume: 20, Issue:5

    Topics: Alkylating Agents; Blood Specimen Collection; Bone Marrow Transplantation; Busulfan; Child; Child, P

1997
Ursodiol prophylaxis against hepatic complications of allogeneic bone marrow transplantation. A randomized, double-blind, placebo-controlled trial.
    Annals of internal medicine, 1998, Jun-15, Volume: 128, Issue:12 Pt 1

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cholagogues and Choleretics; Cyclophosphamide; Double-

1998
High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:12 Pt 2

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transp

1997
Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta
    Blood, 1999, Apr-01, Volume: 93, Issue:7

    Topics: Adolescent; Adult; Alopecia; Bone Marrow Transplantation; Bronchiolitis Obliterans; Busulfan; Catara

1999
Hematopoietic stem cell transplantation for childhood myeloid malignancies after high-dose thiotepa, busulfan and cyclophosphamide.
    Bone marrow transplantation, 1999, Volume: 24, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Combi

1999
Improved survival after bone marrow transplantation for early leukemia using busulfan-cyclophosphamide and individualized prophylaxis against graft-versus-host disease: a long-term follow-up.
    Clinical transplantation, 1999, Volume: 13, Issue:6

    Topics: Aged; Aged, 80 and over; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survi

1999
Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria.
    Haematologica, 2000, Volume: 85, Issue:1

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Follow-Up Studies; Graft Sur

2000
Allogeneic peripheral blood stem cell transplantation in children with hematologic malignancies from HLA-matched siblings.
    Medical and pediatric oncology, 2000, Volume: 34, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busul

2000
Comparison of total body irradiation vs busulfan in combination with cyclophosphamide as conditioning for unrelated stem cell transplantation in CML patients.
    Bone marrow transplantation, 2001, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disea

2001
Dose-reduced conditioning and allogeneic hematopoietic stem cell transplantation from unrelated donors in 42 patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy P

2001
Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: long-term follow-up of 4 randomized studies.
    Blood, 2001, Dec-15, Volume: 98, Issue:13

    Topics: Adolescent; Adult; Alopecia; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cycloph

2001
The gut mucosa barrier is preserved during allogeneic, haemopoietic stem cell transplantation with reduced intensity conditioning.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Adult; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Gastric Muco

2001
Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Cladribine; Combined Modality Therapy; Graf

2002
Treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation after preparation with BuCy2.
    Blood, 1992, Sep-01, Volume: 80, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1992
Phase I study of busulfan and cyclophosphamide in preparation for allogeneic marrow transplant for patients with multiple myeloma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:9

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Dose-Resp

1992
Busulphan, cyclophosphamide, and melphalan as conditioning therapy in allogeneic bone marrow transplants for acute lymphoblastic leukemia.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Cytarabine; Graft

1992
Autologous and allogeneic bone marrow transplantation for childhood acute nonlymphoblastic leukemia.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Cyclosporine; Fol

1992
Phase I study of busulfan, cyclophosphamide, and timed sequential escalating doses of cytarabine followed by bone marrow transplantation.
    Bone marrow transplantation, 1992, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation

1992
Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission: a randomized trial of a busulfan-Cytoxan versus Cytoxan-total body irradiation as preparative regimen: a report from the Group d'Etudes de la Greffe de Moelle Osseuse.
    Blood, 1992, May-15, Volume: 79, Issue:10

    Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantati

1992
Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan/cyclophosphamide.
    Blood, 1992, May-15, Volume: 79, Issue:10

    Topics: Actuarial Analysis; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Follow-U

1992
Treatment for acute myelocytic leukemia with allogeneic bone marrow transplantation following preparation with BuCy2.
    Blood, 1991, Aug-01, Volume: 78, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combin

1991
Bone marrow transplantation with T-cell depleted allografts for the treatment of severe beta thalassemia major.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Bone Marrow Transplantation; Busulfan; Clinical Trials as Topic; Cyclophosphamide; Graft Enhancement

1989
Graft-versus-host disease: effects on long term disease free survival in marrow transplantation for haematological malignancies.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1989
Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen.
    Blood, 1987, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1987

Other Studies

517 other studies available for busulfan and Graft-Versus-Host Disease

ArticleYear
Impact of conditioning intensity and regimen on transplant outcomes in patients with adult T-cell leukemia-lymphoma.
    Bone marrow transplantation, 2021, Volume: 56, Issue:12

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia-Lymphoma,

2021
Fludarabine/busulfan versus busulfan/cyclophosphamide as myeloablative conditioning for myelodysplastic syndrome: a propensity score-matched analysis.
    Bone marrow transplantation, 2021, Volume: 56, Issue:12

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2021
Allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome using treosulfan based compared to other reduced-intensity or myeloablative conditioning regimens. A report of the chronic malignancies working party of the EBMT.
    British journal of haematology, 2021, Volume: 195, Issue:3

    Topics: Adolescent; Adult; Aged; Allografts; Busulfan; Cyclophosphamide; Disease Progression; Female; Follow

2021
Hand-foot syndrome and risk factors for occurrence in hematopoietic stem cell transplantation recipients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:2

    Topics: Busulfan; Female; Graft vs Host Disease; Hand-Foot Syndrome; Hematopoietic Stem Cell Transplantation

2022
Treosulfan-induced myalgia in pediatric hematopoietic stem cell transplantation identified by an electronic health record text mining tool.
    Scientific reports, 2021, 09-27, Volume: 11, Issue:1

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Data Mining; Electronic Health Records; Graft vs Host

2021
Retrospective comparison of hematopoietic stem cell transplantation following reduced-intensity conditioning with fludarabine/low-dose melphalan plus 4 Gy TBI versus fludarabine/ busulfan plus 4 Gy TBI.
    International journal of hematology, 2022, Volume: 115, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell

2022
Combination of treosulfan, fludarabine and cytarabine as conditioning in patients with acute myeloid leukemia, myelodysplastic syndrome and myeloproliferative neoplasms.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:10

    Topics: Busulfan; Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukem

2022
Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation.
    The pharmacogenomics journal, 2022, Volume: 22, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Cohort Studies; DN

2022
Long-term survival with mixed chimerism in patients with AML and MDS transplanted after conditioning with targeted busulfan, fludarabine, and thymoglobulin.
    Bone marrow transplantation, 2022, Volume: 57, Issue:2

    Topics: Antilymphocyte Serum; Busulfan; Chimerism; Cyclophosphamide; Graft vs Host Disease; Hematopoietic St

2022
Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation with Cocktail Conditioning Regimen for the Treatment of Pediatric Patients with Chronic Active Epstein-Barr Virus: A Retrospective Observational Study.
    Stem cells and development, 2022, Volume: 31, Issue:1-2

    Topics: Antilymphocyte Serum; Busulfan; Child; Cyclophosphamide; Cytarabine; Epstein-Barr Virus Infections;

2022
Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia: an effective, low toxicity, TBI-free conditioning regimen.
    Blood advances, 2022, 03-22, Volume: 6, Issue:6

    Topics: Busulfan; Child; Clofarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans

2022
Total body irradiation-based versus busulfan-based myeloablative conditioning for single-unit cord blood transplantation in adults.
    Leukemia & lymphoma, 2022, Volume: 63, Issue:5

    Topics: Adult; Busulfan; Cord Blood Stem Cell Transplantation; Graft vs Host Disease; Hematopoietic Stem Cel

2022
Total body irradiation plus fludarabine versus thiotepa, busulfan plus fludarabine as a myeloablative conditioning for adults with acute lymphoblastic leukemia treated with haploidentical hematopoietic cell transplantation. A study by the Acute Leukemia W
    Bone marrow transplantation, 2022, Volume: 57, Issue:3

    Topics: Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, M

2022
Risk factors and prognosis of non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation.
    International journal of hematology, 2022, Volume: 115, Issue:4

    Topics: Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2022
Hematopoietic stem cell transplantation for Wiskott-Aldrich syndrome: an EBMT Inborn Errors Working Party analysis.
    Blood, 2022, 03-31, Volume: 139, Issue:13

    Topics: Busulfan; Child, Preschool; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2022
[Efficacy and Safety of Cladribine-based Intensified Conditioning Regimen in Hematopoietic Stem Cell Transplantation in Patients with High-Risk Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:1

    Topics: Busulfan; Cladribine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukem

2022
Treosulfan-based conditioning regimen for allogeneic hematopoietic stem cell transplantation in children with non-malignant diseases.
    Bone marrow transplantation, 2022, Volume: 57, Issue:4

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplanta

2022
Dynamics of recent thymic emigrants in pediatric recipients of allogeneic hematopoetic stem cell transplantation.
    Bone marrow transplantation, 2022, Volume: 57, Issue:4

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retrospecti

2022
Radiation-free reduced-intensity hematopoietic stem cell transplantation with in vivo T-cell depletion from matched related and unrelated donors for Fanconi anemia: prognostic factor analysis.
    Experimental hematology, 2022, Volume: 109

    Topics: Busulfan; Fanconi Anemia; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Pr

2022
[Haploidentical stem cell transplantation for acute myeloid leukemia associated with adult-onset Shwachman-Diamond syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2022, Volume: 63, Issue:2

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2022
Myeloablative Versus Reduced-Intensity Conditioning With Fludarabine/Busulfan for Myelodysplastic Syndrome: A Propensity Score-Matched Analysis.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:6

    Topics: Adult; Busulfan; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplast

2022
Role of therapeutic drug monitoring of intravenous Busulfan for prevention of sinusoidal obstructive syndrome in children.
    Pediatric transplantation, 2022, Volume: 26, Issue:5

    Topics: Bayes Theorem; Busulfan; Child; Child, Preschool; Drug Monitoring; Female; Graft vs Host Disease; He

2022
Impact of busulfan pharmacokinetics on outcome in adult patients receiving an allogeneic hematopoietic cell transplantation.
    Bone marrow transplantation, 2022, Volume: 57, Issue:6

    Topics: Adult; Area Under Curve; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2022
Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
    Annals of hematology, 2022, Volume: 101, Issue:6

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, My

2022
Augmented FLAMSA-Bu versus FluBu2 reduced-intensity conditioning in patients with active relapsed/refractory acute myeloid leukemia: an EBMT analysis.
    Bone marrow transplantation, 2022, Volume: 57, Issue:6

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2022
Comparative analysis of Decitabine intensified BUCY2 and BUCY2 conditioning regimen for high-risk MDS patients undergoing allogeneic hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2022, Volume: 57, Issue:7

    Topics: Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retros

2022
Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:8

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; M

2022
Reduced intensity versus non-myeloablative conditioning regimen for haploidentical transplantation and post-transplantation cyclophosphamide in complete remission acute myeloid leukemia: a study from the ALWP of the EBMT.
    Bone marrow transplantation, 2022, Volume: 57, Issue:9

    Topics: Aged; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hu

2022
Low-Dose Total Body Irradiation Added to Fludarabine and Busulfan Reduced-Intensity Conditioning Reduces Graft Failure in Patients with Myelofibrosis.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:9

    Topics: Adult; Busulfan; Graft vs Host Disease; Humans; Primary Myelofibrosis; Retrospective Studies; Transp

2022
Busulfan and cyclophosphamide-based conditioning regimen still holds the promise of being a safe and efficacious regimen for allogeneic transplantation in patients with transfusion-dependent thalassemia, even in high risk.
    European journal of haematology, 2022, Volume: 109, Issue:5

    Topics: Adolescent; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Cyclophosphamide; Graft vs Host

2022
Curative allogeneic hematopoietic stem cell transplantation following reduced toxicity conditioning in adults with primary immunodeficiency.
    Bone marrow transplantation, 2022, Volume: 57, Issue:10

    Topics: Adolescent; Adult; Busulfan; Child; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematopoi

2022
A retrospective study of treosulfan versus busulfan-based conditioning in pediatric patients.
    European journal of haematology, 2022, Volume: 109, Issue:5

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retrospecti

2022
Unmanipulated haploidentical haematopoietic cell transplantation with radiation-free conditioning in Fanconi anaemia: A retrospective analysis from the Chinese Blood and Marrow Transplantation Registry Group.
    British journal of haematology, 2022, Volume: 199, Issue:3

    Topics: Bone Marrow; Busulfan; Cyclophosphamide; Fanconi Anemia; Graft vs Host Disease; Hematopoietic Stem C

2022
Treosulfan-based Reduced-intensity Allogeneic Hematopoietic Cell Transplantation in Adults With Primary Immunodeficiency: A Case Series.
    Anticancer research, 2022, Volume: 42, Issue:9

    Topics: Adult; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Mal

2022
Non-myeloablative allogeneic stem cell transplant with fludarabine and reduced dose cyclophosphamide in acute myeloid leukemia for older adults with comorbidities.
    Bone marrow transplantation, 2022, Volume: 57, Issue:11

    Topics: Aged; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hu

2022
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial.
    Leukemia, 2022, Volume: 36, Issue:11

    Topics: Busulfan; Child; Cyclophosphamide; Etoposide; Follow-Up Studies; Graft vs Host Disease; Hematopoieti

2022
Allogeneic hematopoietic cell transplantation in patients with juvenile myelomonocytic leukemia in Korea: a report of the Korean Pediatric Hematology-Oncology Group.
    Bone marrow transplantation, 2023, Volume: 58, Issue:1

    Topics: Busulfan; Child; Graft vs Host Disease; Hematology; Hematopoietic Stem Cell Transplantation; Humans;

2023
Donor-derived diffuse large B-cell lymphoma after haploidentical stem cell transplantation for acute myeloid leukemia.
    Journal of clinical and experimental hematopathology : JCEH, 2022, Volume: 62, Issue:3

    Topics: Antilymphocyte Serum; Azacitidine; Busulfan; Epstein-Barr Virus Infections; Graft vs Host Disease; H

2022
Thiotepa, busulfan and fludarabine conditioning-regimen is a promising approach for older adult patients with acute lymphoblastic leukemia treated with allogeneic stem cell transplantation.
    Bone marrow transplantation, 2023, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2023
[Allogeneic hematopoietic stem cell transplantation in patients with multiple myeloma].
    Terapevticheskii arkhiv, 2021, Jul-23, Volume: 93, Issue:7

    Topics: Adult; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoieti

2021
Individualized busulfan dosing improves outcomes compared to fixed-dose administration in pre-transplant minimal residual disease-positive acute myeloid leukemia patients with intermediate-risk undergoing allogeneic stem cell transplantation in CR.
    European journal of haematology, 2023, Volume: 110, Issue:2

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2023
Clofarabine and Busulfan Myeloablative Conditioning in Allogeneic Hematopoietic Cell Transplantation for Patients With Active Myeloid Malignancies.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:2

    Topics: Adult; Aged; Busulfan; Clofarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2023
A uniform conditioning regimen of busulfan, fludarabine, and antithymocyte globulin for allogeneic haematopoietic cell transplantation from haploidentical family, matched sibling, or unrelated donors-A single-centre, prospective, explorative study.
    British journal of haematology, 2023, Volume: 200, Issue:5

    Topics: Antilymphocyte Serum; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
Busulfan, fludarabine, and melphalan are effective conditioning for pediatric and young adult patients with myeloid malignancies underdoing matched sibling or alternative donor transplantation.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:2

    Topics: Adolescent; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
High Incidences of Acute and Chronic Graft-Versus-Host Disease after Hematopoietic Cell Transplants for Acute Myeloid Leukemia Using Thiotepa, Busulfan, and Fludarabine Pretransplant Conditioning.
    Acta haematologica, 2023, Volume: 146, Issue:1

    Topics: Bronchiolitis Obliterans Syndrome; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpla

2023
High Incidences of Acute and Chronic Graft-Versus-Host Disease after Hematopoietic Cell Transplants for Acute Myeloid Leukemia Using Thiotepa, Busulfan, and Fludarabine Pretransplant Conditioning.
    Acta haematologica, 2023, Volume: 146, Issue:1

    Topics: Bronchiolitis Obliterans Syndrome; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpla

2023
High Incidences of Acute and Chronic Graft-Versus-Host Disease after Hematopoietic Cell Transplants for Acute Myeloid Leukemia Using Thiotepa, Busulfan, and Fludarabine Pretransplant Conditioning.
    Acta haematologica, 2023, Volume: 146, Issue:1

    Topics: Bronchiolitis Obliterans Syndrome; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpla

2023
High Incidences of Acute and Chronic Graft-Versus-Host Disease after Hematopoietic Cell Transplants for Acute Myeloid Leukemia Using Thiotepa, Busulfan, and Fludarabine Pretransplant Conditioning.
    Acta haematologica, 2023, Volume: 146, Issue:1

    Topics: Bronchiolitis Obliterans Syndrome; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpla

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Second allogeneic hematopoietic stem cell transplantation in patients with inborn errors of immunity.
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2023
Second allogeneic hematopoietic stem cell transplantation in patients with inborn errors of immunity.
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2023
Second allogeneic hematopoietic stem cell transplantation in patients with inborn errors of immunity.
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2023
Second allogeneic hematopoietic stem cell transplantation in patients with inborn errors of immunity.
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2023
Total body irradiation plus fludarabine versus busulfan plus fludarabine as a myeloablative conditioning for adults with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study on behalf of the Acute Leukemia Working Par
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Acute Disease; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Total body irradiation plus fludarabine versus busulfan plus fludarabine as a myeloablative conditioning for adults with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study on behalf of the Acute Leukemia Working Par
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Acute Disease; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Total body irradiation plus fludarabine versus busulfan plus fludarabine as a myeloablative conditioning for adults with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study on behalf of the Acute Leukemia Working Par
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Acute Disease; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Total body irradiation plus fludarabine versus busulfan plus fludarabine as a myeloablative conditioning for adults with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study on behalf of the Acute Leukemia Working Par
    Bone marrow transplantation, 2023, Volume: 58, Issue:3

    Topics: Acute Disease; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:1

    Topics: Administration, Intravenous; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpl

2023
Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:1

    Topics: Administration, Intravenous; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpl

2023
Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:1

    Topics: Administration, Intravenous; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpl

2023
Evaluation of different pharmacokinetically guided IV busulfan exposure ranges on adult patient outcomes after hematopoietic stem cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:1

    Topics: Administration, Intravenous; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transpl

2023
Transplantation using targeted busulfan for Diamond-Blackfan anemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2023, Volume: 65, Issue:1

    Topics: Anemia, Diamond-Blackfan; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2023
Transplantation using targeted busulfan for Diamond-Blackfan anemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2023, Volume: 65, Issue:1

    Topics: Anemia, Diamond-Blackfan; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2023
Transplantation using targeted busulfan for Diamond-Blackfan anemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2023, Volume: 65, Issue:1

    Topics: Anemia, Diamond-Blackfan; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2023
Transplantation using targeted busulfan for Diamond-Blackfan anemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2023, Volume: 65, Issue:1

    Topics: Anemia, Diamond-Blackfan; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2023
Fludarabine versus cyclophospamide in combination with myeloablative total body irradiation as conditioning for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation. A study from the Acute Leukemia Working Party
    American journal of hematology, 2023, Volume: 98, Issue:4

    Topics: Acute Disease; Adult; Bone Marrow; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic

2023
Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:3

    Topics: Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, N

2023
Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis.
    Haematologica, 2023, Jul-01, Volume: 108, Issue:7

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transp

2023
Haematopoietic cell transplantation for children with acute megakaryoblastic leukaemia without Down syndrome.
    British journal of haematology, 2023, Volume: 201, Issue:4

    Topics: Busulfan; Child; Down Syndrome; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
A single-center experience of haploidentical stem cell transplantation in hematological malignancies.
    Turkish journal of medical sciences, 2023, Volume: 53, Issue:1

    Topics: Busulfan; Child; Cyclophosphamide; Cyclosporine; Graft vs Host Disease; Hematologic Neoplasms; Hemat

2023
Fludarabine/TBI 8 Gy versus fludarabine/treosulfan conditioning in patients with AML in first complete remission: a study from the Acute Leukemia Working Party of the EBMT.
    Bone marrow transplantation, 2023, Volume: 58, Issue:6

    Topics: Acute Disease; Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2023
Effect of pharmacokinetics and pharmacogenomics in adults with allogeneic hematopoietic cell transplantation conditioned with Busulfan.
    Bone marrow transplantation, 2023, Volume: 58, Issue:7

    Topics: Adult; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2023
Total body irradiation versus busulfan based intermediate intensity conditioning for stem cell transplantation in ALL patients >45 years-a registry-based study by the Acute Leukemia Working Party of the EBMT.
    Bone marrow transplantation, 2023, Volume: 58, Issue:8

    Topics: Acute Disease; Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Human

2023
Improved Outcome Following Busulfan-Based Conditioning in Children with Functional Neutrophil Disorders Undergoing Hematopoietic Stem Cell Transplant from HLA-Matched Donors.
    Journal of clinical immunology, 2023, Volume: 43, Issue:7

    Topics: Busulfan; Child; Child, Preschool; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematopoie

2023
Assessment of Stem Cell Transplant Eligibility in Recipients with Oral Foci of Infection: Appropriate Conditioning Regimens.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2023, Volume: 21, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Graft vs Host Disease; H

2023
Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Child; Cyclophosphamide; Cytarabine; Graft vs

2023
Treosulfan, thiotepa and fludarabine conditioning regimen prior to first allogeneic stem cell transplantation in acute myeloid leukemia and high-risk myelodysplastic syndromes: a single center experience.
    Bone marrow transplantation, 2023, Volume: 58, Issue:9

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2023
Donor Age Influences Graft-Versus-Host Disease Relapse-Free Survival after Allogeneic Stem Cell Transplant in Elderly Patients in Two Countries from Latin America.
    Hematology/oncology and stem cell therapy, 2023, May-23, Volume: 16, Issue:4

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Latin Americ

2023
The impact of Treosulfan-based conditioning for inborn errors of immunity: Is dose monitoring crucial?
    Clinical transplantation, 2023, Volume: 37, Issue:9

    Topics: Busulfan; Child; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantati

2023
Myeloablative Dose of Busulfan and Fludarabine Combined with In Vivo T Cell Depletion Is Safe and Effective Conditioning for Acute Myeloid Leukemia and Myelodysplastic Syndrome Patients.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:11

    Topics: Busulfan; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Synd

2023
Outcome of first or second transplantation using unrelated umbilical cord blood without ATG conditioning regimen for pediatric bone marrow failure disorders.
    Blood cells, molecules & diseases, 2024, Volume: 104

    Topics: Antilymphocyte Serum; Bone Marrow Failure Disorders; Busulfan; Child; Cyclophosphamide; Fetal Blood;

2024
Transplantation Outcomes of Myelofibrosis with Busulfan and Fludarabine Myeloablative Conditioning.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:12

    Topics: Busulfan; Graft vs Host Disease; Humans; Methotrexate; Primary Myelofibrosis; Recurrence; Tacrolimus

2023
Busulfan and subsequent malignancy: An evidence-based risk assessment.
    Pediatric blood & cancer, 2024, Volume: 71, Issue:1

    Topics: Adult; Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leuk

2024
Efficacy of venetoclax combined with decitabine conditioning regimen for allogeneic hematopoietic stem cell transplantation in high-risk and elderly patients with myeloid neoplasms.
    Annals of hematology, 2023, Volume: 102, Issue:12

    Topics: Aged; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2023
[Long-term outcome of hematopoietic stem cell transplantation in two children with Mucopolysaccharidosis].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2023, Dec-10, Volume: 40, Issue:12

    Topics: Busulfan; Child; Child, Preschool; China; Female; Graft vs Host Disease; Hematopoietic Stem Cell Tra

2023
The impact of low dose busulfan on gonodal function after allogeneic hematopoietic stem cell transplantation for aplastic anemia.
    Bone marrow transplantation, 2020, Volume: 55, Issue:6

    Topics: Anemia, Aplastic; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2020
Allogeneic hematopoietic stem cell transplantation with fludarabine, busulfan, and thiotepa conditioning is associated with favorable outcomes in myelofibrosis.
    Bone marrow transplantation, 2020, Volume: 55, Issue:1

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Primary Myelofibro

2020
A New Conditioning Regimen Can Significantly Promote Post-Transplant Immune Reconstitution and Improve the Outcome of Umbilical Cord Blood Transplantation for Patients.
    Stem cells and development, 2019, 10-15, Volume: 28, Issue:20

    Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busul

2019
Reduced intensity conditioning regimens including alkylating chemotherapy do not alter survival outcomes after allogeneic hematopoietic cell transplantation in chronic lymphocytic leukemia compared to low-intensity non-myeloablative conditioning.
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cy

2019
Conditioning Regimen of 5-Day Decitabine Administration for Allogeneic Stem Cell Transplantation in Patients with Myelodysplastic Syndrome and Myeloproliferative Neoplasms.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:2

    Topics: Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukem

2020
Comparison of non-myeloablative and reduced-intensity allogeneic stem cell transplantation in older patients with myelodysplastic syndromes.
    American journal of hematology, 2019, Volume: 94, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Busulfan; Comorbidity; Graft vs Host Disease; Humans; Immunosu

2019
Long-Term Outcomes of Patients with Acute Myelogenous Leukemia Treated with Myeloablative Fractionated Total Body Irradiation TBI-Based Conditioning with a Tacrolimus- and Sirolimus-Based Graft-versus-Host Disease Prophylaxis Regimen: 6-Year Follow-Up fro
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Follow-Up Studies; Graft vs Host Disease; Hematopoiet

2020
Conditioning Intensity for Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients with Poor-Prognosis Cytogenetics in First Complete Remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:3

    Topics: Adult; Busulfan; Cytogenetic Analysis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantatio

2020
Successful Salvage Haploidentical Alpha-Beta T Cell-Depleted Stem Cell Transplantation After Busulfan-Based Myeloablation in a Patient With IPEX Syndrome: A Case Report.
    Transplantation proceedings, 2019, Volume: 51, Issue:9

    Topics: Antilymphocyte Serum; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2019
Fludarabine/busulfan versus fludarabine/total-body-irradiation (2 Gy) as conditioning prior to allogeneic stem cell transplantation in patients (≥60 years) with acute myelogenous leukemia: a study of the acute leukemia working party of the EBMT.
    Bone marrow transplantation, 2020, Volume: 55, Issue:4

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, My

2020
Risk factors for the development of cutaneous melanoma after allogeneic hematopoietic cell transplantation.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Busulfan; Case-Control Studies; Child; Child, Preschool; Femal

2020
Factors predicting endocrine late effects in childhood cancer survivors from a Japanese hospital.
    Endocrine journal, 2020, Feb-28, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Busulfan; Cancer Survivors; Child; Chroni

2020
Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver after Busulfan-Cyclophosphamide Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation.
    Clinical and translational science, 2020, Volume: 13, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Busulfan; Capillaries; Child; Child, Preschool; Cholagogues and C

2020
Reduced-Toxicity (BuFlu) Conditioning Is Better Tolerated but Has a Higher Second Transplantation Rate Compared to Myeloablative Conditioning (BuCy) in Children with Inherited Metabolic Disorders.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2020
Clinical Outcomes after Allogeneic Hematopoietic Stem Cell Transplantation in Children with Juvenile Myelomonocytic Leukemia: A Report from the Japan Society for Hematopoietic Cell Transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:5

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Japan; Leuk

2020
Allogeneic Hemopoietic Stem Cell Transplants in Patients with Acute Myeloid Leukemia (AML) Prepared with Busulfan and Fludarabine (BUFLU) or Thiotepa, Busulfan, and Fludarabine (TBF): A Retrospective Study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:4

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2020
Outcome of allogeneic Hematopoietic Stem Cell Transplantation on Diamond-Blackfan anemia using busulfan-based myeloablative regimen.
    The Turkish journal of pediatrics, 2019, Volume: 61, Issue:3

    Topics: Adolescent; Anemia, Diamond-Blackfan; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Cyclo

2019
Hematopoietic Stem Cell Transplantation for Severe Thalassemia Patients from Haploidentical Donors Using a Novel Conditioning Regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:6

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Thalassemia

2020
Fludarabine/Busulfan Conditioning-Based Allogeneic Hematopoietic Cell Transplantation for Myelofibrosis: Role of Ruxolitinib in Improving Survival Outcomes.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:5

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Nitriles; Pr

2020
Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospec
    Bone marrow transplantation, 2020, Volume: 55, Issue:10

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2020
Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:6

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Sy

2020
Reduced-intensity stem cell transplantation for acute myeloid leukemia with fludarabine-based conditioning with intravenous busulfan versus melphalan.
    Bone marrow transplantation, 2020, Volume: 55, Issue:10

    Topics: Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, M

2020
Hematopoietic stem cell transplantation in children with Griscelli syndrome type 2: a single-center report on 35 patients.
    Bone marrow transplantation, 2020, Volume: 55, Issue:10

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lymphohisti

2020
Impact of type of reduced-intensity conditioning regimen on the outcomes of allogeneic haematopoietic cell transplantation in classical Hodgkin lymphoma.
    British journal of haematology, 2020, Volume: 190, Issue:4

    Topics: Adolescent; Adult; Aged; Allografts; Busulfan; Cause of Death; Comorbidity; Cyclophosphamide; Female

2020
Comparison of reduced-intensity conditioning regimens in patients with acute lymphoblastic leukemia >45 years undergoing allogeneic stem cell transplantation-a retrospective study by the Acute Leukemia Working Party of EBMT.
    Bone marrow transplantation, 2020, Volume: 55, Issue:8

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2020
Comparison of reduced-intensity/toxicity conditioning regimens for umbilical cord blood transplantation for lymphoid malignancies.
    Bone marrow transplantation, 2020, Volume: 55, Issue:11

    Topics: Busulfan; Cord Blood Stem Cell Transplantation; Graft vs Host Disease; Hematopoietic Stem Cell Trans

2020
Graft-versus-host Disease Prophylaxis With Abatacept Reduces Severe Acute Graft-versus-host Disease in Allogeneic Hematopoietic Stem Cell Transplant for Beta-thalassemia Major With Busulfan, Fludarabine, and Thiotepa.
    Transplantation, 2021, 04-01, Volume: 105, Issue:4

    Topics: Abatacept; Adolescent; beta-Thalassemia; Busulfan; Calcineurin Inhibitors; Child; Child, Preschool;

2021
Reduced-Intensity Conditioning with Busulfan and Fludarabine for Allogeneic Hematopoietic Stem Cell Transplantation in Acute Lymphoblastic Leukemia.
    Yonsei medical journal, 2020, Volume: 61, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem

2020
Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:9

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retrospecti

2020
Irradiation free conditioning regimen is associated with high relapse rate in Egyptian patients with acute lymphoblastic leukemia following allogeneic hematopoietic stem cell transplantation.
    Journal of the Egyptian National Cancer Institute, 2020, Jun-15, Volume: 32, Issue:1

    Topics: Adult; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplant

2020
Comparison of total body irradiation
    Haematologica, 2021, 07-01, Volume: 106, Issue:7

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2021
Hematopoietic cell transplant outcomes after myeloablative conditioning with fludarabine, busulfan, low-dose total body irradiation, and rabbit antithymocyte globulin.
    Clinical transplantation, 2020, Volume: 34, Issue:9

    Topics: Aged; Antilymphocyte Serum; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation

2020
Splenomegaly May Increase the Risk of Rejection in Low-Risk Matched Related Donor Transplant for Thalassemia, This Risk Can Be Partially Overcome by Additional Immunosuppression during Conditioning.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:10

    Topics: Antilymphocyte Serum; Busulfan; Cyclophosphamide; France; Germany; Graft vs Host Disease; Humans; Re

2020
Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Chime

2020
Feasibility of thiotepa addition to the fludarabine-busulfan conditioning with tacrolimus/sirolimus as graft vs host disease prophylaxis.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:8

    Topics: Busulfan; Feasibility Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Human

2020
Comparison of Myeloablative (CyTBI, BuCy) versus Reduced-Intensity (FluBu2TBI400) Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia Patients with Pretransplant Low WT1 Expression.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:11

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2020
Pubertal outcomes of children transplanted with allogeneic stem cells after myeloablative total body irradiation or busulfan: Influence of age and sex is confirmed, while a role of chronic graft-versus-host disease in delayed puberty onset is revealed.
    Pediatric transplantation, 2020, Volume: 24, Issue:6

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Disease; Hema

2020
FLAMSA-Based Reduced-Intensity Conditioning versus Myeloablative Conditioning in Younger Patients with Relapsed/Refractory Acute Myeloid Leukemia with Active Disease at the Time of Allogeneic Stem Cell Transplantation: An Analysis from the Acute Leukemia
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Bone Marrow; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplanta

2020
Total body irradiation + fludarabine compared to busulfan + fludarabine as "reduced-toxicity conditioning" for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acut
    Bone marrow transplantation, 2021, Volume: 56, Issue:2

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2021
Antithymocyte globulin administration in patients with profound lymphopenia receiving a PBSC purine analog/busulfan-based conditioning regimen allograft.
    Scientific reports, 2020, 09-21, Volume: 10, Issue:1

    Topics: Adult; Aged; Allografts; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Female; Graft vs Hos

2020
Decitabine prior to salvaged cord blood transplantation for acute myeloid leukaemia/myelodysplastic syndrome not in remission.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool

2020
Thiotepa-busulfan-fludarabine as a conditioning regimen for patients with myelofibrosis undergoing allogeneic hematopoietic transplantation: a single center experience.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:2

    Topics: Adult; Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Middl

2021
Comparable outcomes of haploidentical transplant with TBF conditioning versus matched unrelated donor with fludarabine/busulfan conditioning for acute myeloid leukemia.
    Bone marrow transplantation, 2021, Volume: 56, Issue:3

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2021
Evaluation of six different types of sequential conditioning regimens for allogeneic stem cell transplantation in relapsed/refractory acute myelogenous leukemia - a study of the Acute Leukemia Working Party of the EBMT.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:2

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, My

2021
Prediction of Acute Graft versus Host Disease and Relapse by Endogenous Metabolomic Compounds in Patients Receiving Personalized Busulfan-Based Conditioning.
    Journal of proteome research, 2021, 01-01, Volume: 20, Issue:1

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Metabolomics; Prog

2021
Comparison of fixed dose reduced-intensity conditioning with fludarabine and busulfan to PK-guided busulfan AUC (FluBu4K) in hematopoietic stem cell transplant for AML/MDS.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:4

    Topics: Adult; Area Under Curve; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2021
Second haploidentical stem cell transplantation for primary graft failure.
    Bone marrow transplantation, 2021, Volume: 56, Issue:6

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2021
Testosterone deficiency in men surviving childhood acute leukemia after treatment with hematopoietic stem cell transplantation or testicular radiation: an L.E.A. study.
    Bone marrow transplantation, 2021, Volume: 56, Issue:6

    Topics: Busulfan; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, M

2021
Hematopoietic cell transplant in pediatric acute myeloid leukemia after similar upfront therapy; a comparison of conditioning regimens.
    Bone marrow transplantation, 2021, Volume: 56, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Graft vs Host Dis

2021
Thiotepa-busulfan-fludarabine (TBF) conditioning regimen in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis: an outcome analysis from the Chronic Malignancies Working Party of the EBMT.
    Bone marrow transplantation, 2021, Volume: 56, Issue:7

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Neopl

2021
Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases.
    Journal of clinical immunology, 2021, Volume: 41, Issue:5

    Topics: Busulfan; Child, Preschool; Drug Combinations; Female; Graft vs Host Disease; Hematopoietic Stem Cel

2021
Comparison of myeloablative and reduced intensity conditioning unrelated donor allogeneic peripheral blood stem cell transplant outcomes for AML using thymoglobulin for GVHD prophylaxis.
    Annals of hematology, 2021, Volume: 100, Issue:4

    Topics: Aged; Allografts; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Humans; Immunosuppr

2021
Allogeneic hematopoietic cell transplantation using fludarabine plus myeloablative busulfan and melphalan confers promising survival in high-risk hematopoietic neoplasms: a single-center retrospective analysis.
    Hematology (Amsterdam, Netherlands), 2021, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality

2021
Comparison of Total Body Irradiation-based Versus Chemotherapy-based Conditionings for Early Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Children With ALL.
    Journal of pediatric hematology/oncology, 2021, Oct-01, Volume: 43, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Combi

2021
Low-dose decitabine as part of a modified Bu-Cy conditioning regimen improves survival in AML patients with active disease undergoing allogeneic hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2021, Volume: 56, Issue:7

    Topics: Busulfan; Cyclophosphamide; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantati

2021
Adding melphalan to fludarabine and a myeloablative dose of busulfan improved survival after allogeneic hematopoietic stem cell transplantation in a propensity score-matched cohort of hematological malignancies.
    Bone marrow transplantation, 2021, Volume: 56, Issue:7

    Topics: Busulfan; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hum

2021
Combining Three Different Pretransplantation Scores Improves Predictive Value in Patients after Haploidentical Stem Cell Transplantation with Thiotepa, Busulfan, and Fludarabine Conditioning and Post-Transplantation Cyclophosphamide.
    Transplantation and cellular therapy, 2021, Volume: 27, Issue:7

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2021
Successful Allogeneic Peripheral Blood Stem Cell Transplantation in 4 Wiskott-Aldrich Syndrome Patients.
    Journal of pediatric hematology/oncology, 2022, Mar-01, Volume: 44, Issue:2

    Topics: Busulfan; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Peri

2022
Acute graft-versus-host disease is the foremost cause of late nonrelapse mortality.
    Bone marrow transplantation, 2021, Volume: 56, Issue:8

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Retrospective Stud

2021
Radiation-free myeloablative conditioning consisting of fludarabine added to full-dose busulfan and cyclophosphamide in single-unit cord blood transplantation for adults.
    European journal of haematology, 2021, Volume: 107, Issue:3

    Topics: Adult; Blood Platelets; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Drug Admin

2021
Comparison of fludarabine, a myeloablative dose of busulfan, and melphalan vs conventional myeloablative conditioning regimen in patients with relapse and refractory acute myeloid leukemia in non-remission status.
    Bone marrow transplantation, 2021, Volume: 56, Issue:9

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid,

2021
Busulfan-containing conditioning regimens in allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia: A Taiwan observational study.
    Cancer reports (Hoboken, N.J.), 2022, Volume: 5, Issue:3

    Topics: Adult; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; H

2022
[Cutaneous complications following hematopoietic stem cell transplantation].
    Bulletin du cancer, 2021, Volume: 108, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Allografts; Busulfan; Candidiasis; Chickenpox; Child; Chronic Dise

2021
Comparison of hematopoietic cell transplant conditioning regimens for hemophagocytic lymphohistiocytosis disorders.
    The Journal of allergy and clinical immunology, 2022, Volume: 149, Issue:3

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2022
Feasibility and Efficacy of a Pharmacokinetics-Guided Busulfan Conditioning Regimen for Allogeneic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis in Adult Patients with Hematologic Malignancie
    Transplantation and cellular therapy, 2021, Volume: 27, Issue:11

    Topics: Busulfan; Cyclophosphamide; Feasibility Studies; Graft vs Host Disease; Hematologic Neoplasms; Hemat

2021
Fludarabine and Melphalan Compared with Reduced Doses of Busulfan and Fludarabine Improve Transplantation Outcomes in Older Patients with Myelodysplastic Syndromes.
    Transplantation and cellular therapy, 2021, Volume: 27, Issue:11

    Topics: Aged; Busulfan; Graft vs Host Disease; Humans; Melphalan; Middle Aged; Myelodysplastic Syndromes; Su

2021
Permanent diffuse alopecia after haematopoietic stem cell transplantation in childhood.
    Bone marrow transplantation, 2017, Volume: 52, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Alopecia; Busulfan; Child; Child, Preschool; Cross-Sectional Studi

2017
Reduced BUCY 2 and G-CSF-primed bone marrow associates with low graft-versus-host-disease and transplant-related mortality in allogeneic HSCT.
    Annals of hematology, 2017, Volume: 96, Issue:9

    Topics: Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan

2017
A Chemotherapy-Only Regimen of Busulfan, Melphalan, and Fludarabine, and Rabbit Antithymocyte Globulin Followed by Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplantations for the Treatment of Myeloid Malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protoco

2017
Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:4

    Topics: Adult; Age Factors; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Follow-Up Studies; Gr

2018
Monitoring of Busulphan Concentrations in Children Undergone Hematopoietic Stem Cell Transplantation: Unicentric Experience over 10 years.
    European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:2

    Topics: Area Under Curve; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic St

2018
A novel drug interaction between busulfan and blinatumomab.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:1

    Topics: Adult; Antibodies, Bispecific; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; D

2019
Reduced-intensity versus reduced-toxicity myeloablative fludarabine/busulfan-based conditioning regimens for allografted non-Hodgkin lymphoma adult patients: a retrospective study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cel
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Sep-01, Volume: 28, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Graft vs Host Disease

2017
Fludarabine and Busulfan versus Fludarabine, Cyclophosphamide, and Rituximab as Reduced-Intensity Conditioning for Allogeneic Transplantation in Follicular Lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Calcineurin Inhibitors; Cyclo

2018
Outcomes of Unrelated Donor Stem Cell Transplantion with Post-Transplant Cyclophosphamide for Graft-versus-Host Disease Prophylaxis in Patients with Severe Sickle Cell Disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:2

    Topics: Adolescent; Anemia, Sickle Cell; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocol

2018
Allogeneic Hematopoietic Stem Cell Transplantation for GATA2 Deficiency Using a Busulfan-Based Regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:6

    Topics: Adult; Aged; Busulfan; Disease-Free Survival; Female; GATA2 Deficiency; Graft vs Host Disease; Hemat

2018
A Comparison of the Myeloablative Conditioning Regimen Fludarabine/Busulfan with Cyclophosphamide/Total Body Irradiation, for Allogeneic Stem Cell Transplantation in the Modern Era: A Cohort Analysis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:8

    Topics: Adult; Aged; Busulfan; Cohort Studies; Cyclophosphamide; Female; Graft vs Host Disease; Hematologic

2018
[Treatment of four cases of Fanconi anemia by allogeneic hematopoietic stem cell transplantation with low intensity conditional regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2018, Mar-14, Volume: 39, Issue:3

    Topics: Busulfan; Fanconi Anemia; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Tr

2018
Posttransplant Cyclophosphamide for HLA-haploidentical Transplantation in Patients With Mucopolysaccharidosis.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6

    Topics: Allografts; Antilymphocyte Serum; Busulfan; Child, Preschool; Cyclophosphamide; Disease-Free Surviva

2018
A new intensive conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with refractory or relapsed acute myeloid leukemia.
    Medicine, 2018, Volume: 97, Issue:17

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Cystitis; Cytarabine; Cytomegalovirus Infections; Dru

2018
Comparison of Different Conditioning Regimens of Haploidentical Hematopoietic Stem Cell Transplant in Patients With Acute Myeloid Leukemia.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2018, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Busulfan; China; Cyclophosphamide; Disease-Free Survival; Drug Therapy, Combinati

2018
Comparison of reduced intensity conditioning regimens used in patients undergoing hematopoietic stem cell transplantation for myelofibrosis.
    Bone marrow transplantation, 2019, Volume: 54, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Carmustine; Chimerism; Female; Graft vs Host Disease;

2019
Busulfan-based myeloablative conditioning regimens for haploidentical transplantation in high-risk acute leukemias and myelodysplastic syndromes.
    European journal of haematology, 2018, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Aged; Busulfan; Combined Modality Therapy; Female; Graft vs Host Disease; Hematop

2018
Long-term outcomes of total body irradiation plus cyclophosphamide versus busulfan plus cyclophosphamide as conditioning regimen for acute lymphoblastic leukemia: a comparative study.
    Annals of hematology, 2018, Volume: 97, Issue:10

    Topics: Adult; Age Factors; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Follow-Up Studies; Gr

2018
Haematopoietic stem cell transplant for hyper-IgM syndrome due to CD40 defects: a single-centre experience.
    Bone marrow transplantation, 2019, Volume: 54, Issue:1

    Topics: Antilymphocyte Serum; B-Lymphocytes; Busulfan; CD40 Antigens; Child, Preschool; Cyclophosphamide; Di

2019
Fludarabine and busulfan plus low-dose TBI as reduced intensity conditioning in older patients undergoing allogeneic hematopoietic cell transplant for myeloid malignancies.
    Annals of hematology, 2018, Volume: 97, Issue:10

    Topics: Aged; Aged, 80 and over; Allografts; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combi

2018
Outcome of treosulfan-based reduced-toxicity conditioning regimens for HSCT in high-risk patients with primary immune deficiencies.
    Pediatric transplantation, 2018, Volume: 22, Issue:7

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combinati

2018
Thiotepa, busulfan and fludarabine compared to busulfan and cyclophosphamide as conditioning regimen for allogeneic stem cell transplant from matched siblings and unrelated donors for acute myeloid leukemia.
    American journal of hematology, 2018, Volume: 93, Issue:10

    Topics: Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplan

2018
Retrospective study of the digestive tract mucositis derived from myeloablative and non-myeloablative/reduced-intensity conditionings with busulfan in hematopoietic cell transplantation patient.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:3

    Topics: Adult; Aged; Busulfan; Digestive System Diseases; Female; Graft vs Host Disease; Hematopoietic Stem

2019
Fludarabine, busulfan, and low-dose TBI conditioning versus cyclophosphamide and TBI in allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Thera

2019
[Treatment of 30 elderly patients with advanced myeloid neoplasm by allogeneic hematopoietic stem cell transplantation].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2018, Aug-14, Volume: 39, Issue:8

    Topics: Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, My

2018
The study of engraftment after hematopoietic stem cell transplantation: From the presence of mixed chimerism to the development of immunological tolerance.
    HLA, 2018, Volume: 92 Suppl 2

    Topics: Antigens, CD; beta-Thalassemia; Busulfan; Cohort Studies; Cyclophosphamide; Gene Expression; Graft R

2018
Allogeneic hematopoietic stem cell transplantation in adolescent patients with chronic granulomatous disease.
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:3

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Granulomatous Disease,

2019
Early fluctuations in busulfan levels with therapeutic dose monitoring during allogeneic stem cell transplantation: do they matter?
    Leukemia & lymphoma, 2019, Volume: 60, Issue:8

    Topics: Adult; Aged; Busulfan; Drug Monitoring; Female; Graft Survival; Graft vs Host Disease; Hematopoietic

2019
Sequential therapy for patients with primary refractory acute myeloid leukemia: a historical prospective analysis of the German and Israeli experience.
    Haematologica, 2019, Volume: 104, Issue:9

    Topics: Adolescent; Adult; Aged; Busulfan; Female; Germany; Graft vs Host Disease; Hematopoietic Stem Cell T

2019
Atypical cytological changes mimicking SIL of the uterine cervix in allogenic hematopoietic stem cell transplantation recipients treated with busulfan.
    Cancer cytopathology, 2019, Volume: 127, Issue:6

    Topics: Adult; Busulfan; Cervix Uteri; Colposcopy; Diagnostic Errors; False Positive Reactions; Female; Foll

2019
[Decitabine-based conditioning regimen is feasible and effective in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2019, Jun-14, Volume: 40, Issue:6

    Topics: Adult; Busulfan; Decitabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2019
Comparison of total body irradiation plus cyclophosphamide with busulfan plus cyclophosphamide as conditioning regimens in patients with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplant.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide

2013
Ex vivo T cell-depleted versus unmodified allografts in patients with acute myeloid leukemia in first complete remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:6

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Trans

2013
Increased risk of gastrointestinal acute GVHD following the addition of melphalan to busulfan/cyclophosphamide conditioning.
    Pediatric transplantation, 2013, Volume: 17, Issue:3

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Gastrointestinal Tract; Gra

2013
Comparison of outcomes after two standards-of-care reduced-intensity conditioning regimens and two different graft sources for allogeneic stem cell transplantation in adults with hematologic diseases: a single-center analysis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:6

    Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide;

2013
A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2013, Volume: 26, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Group Incompatibility; Bronchiolitis Obliterans; Busulfan; Case-Contr

2013
Busulfan dose intensity and outcomes in reduced-intensity allogeneic peripheral blood stem cell transplantation for myelodysplastic syndrome or acute myeloid leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:6

    Topics: Aged; Busulfan; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged;

2013
Pilot study of prophylactic ex vivo costimulated donor leukocyte infusion after reduced-intensity conditioned allogeneic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:7

    Topics: Aged; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Busulfan; Drug Administ

2013
Improved clinical outcomes of high risk β thalassemia major patients undergoing a HLA matched related allogeneic stem cell transplant with a treosulfan based conditioning regimen and peripheral blood stem cell grafts.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adolescent; beta-Thalassemia; Bone Marrow Cells; Busulfan; Cause of Death; Child; Child, Preschool;

2013
National Institutes of Health classification for chronic graft-versus-host disease predicts outcome of allo-hematopoietic stem cell transplant after fludarabine-busulfan-antithymocyte globulin conditioning regimen.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busul

2014
Allogeneic hematopoietic stem-cell transplantation for acute myeloid leukemia in remission: comparison of intravenous busulfan plus cyclophosphamide (Cy) versus total-body irradiation plus Cy as conditioning regimen--a report from the acute leukemia worki
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Oct-01, Volume: 31, Issue:28

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Chemoradiotherapy

2013
Pharmacokinetically-targeted BU and fludarabine as conditioning before allogeneic hematopoietic cell transplantation for adults with ALL in first remission.
    Bone marrow transplantation, 2014, Volume: 49, Issue:1

    Topics: Adult; Aged; Busulfan; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Graft vs Hos

2014
An anti-human thymocyte globulin-based reduced-intensity conditioning regimen is associated with a higher quality of life and lower organ toxicity without affecting lymphocyte reconstitution.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adolescent; Adult; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Hematologic Neopla

2013
Reduced-intensity conditioning therapy with fludarabine, idarubicin, busulfan and cytarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia and myelodysplastic syndrome.
    Leukemia research, 2013, Volume: 37, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool

2013
Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation.
    Haematologica, 2014, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Bilirubin; Busulfan; Cell Line, Tumor; Cytokines; Female; Genotype; Glutathione T

2014
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Blood Specimen Collection; Busulfan; Child; Child, Pr

2014
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Blood Specimen Collection; Busulfan; Child; Child, Pr

2014
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Blood Specimen Collection; Busulfan; Child; Child, Pr

2014
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Blood Specimen Collection; Busulfan; Child; Child, Pr

2014
Allogeneic hematopoietic stem cell transplantation for infants with idiopathic myelofibrosis.
    Pediatric transplantation, 2013, Volume: 17, Issue:8

    Topics: Blood Platelets; Busulfan; Child, Preschool; Cohort Studies; Cyclophosphamide; Female; Follow-Up Stu

2013
A conditioning platform based on fludarabine, busulfan, and 2 days of rabbit antithymocyte globulin results in promising results in patients undergoing allogeneic transplantation from both matched and mismatched unrelated donor.
    American journal of hematology, 2014, Volume: 89, Issue:1

    Topics: Adult; Age Factors; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan;

2014
Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis.
    Haematologica, 2014, Volume: 99, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Female; Graft Surv

2014
Donor T-cell chimerism and early post-transplant cytomegalovirus viremia in patients treated with myeloablative allogeneic hematopoietic stem cell transplant.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Busulfan; Chimerism; Cohort Studies; Cyclophosphamide; Cyclosporine; Cytome

2014
Fludarabine and exposure-targeted busulfan compares favorably with busulfan/cyclophosphamide-based regimens in pediatric hematopoietic cell transplantation: maintaining efficacy with less toxicity.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:3

    Topics: Adenoviridae Infections; Adolescent; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Fo

2014
Antithymocyte globulin in reduced-intensity conditioning regimen allows a high disease-free survival exempt of long-term chronic graft-versus-host disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:3

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Chronic Disease; Female; Graft v

2014
Impact on long-term OS of conditioning regimen in allogeneic BMT for children with AML in first CR: TBI+CY versus BU+CY: a report from the Société Française de Greffe de Moelle et de Thérapie Cellulaire.
    Bone marrow transplantation, 2014, Volume: 49, Issue:3

    Topics: Adolescent; Body Weight; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; France; Graft

2014
Predictors and impact of thirty-day readmission on patient outcomes and health care costs after reduced-toxicity conditioning allogeneic hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Busulfan; Cross Infection; Female; Graft vs Host Disease; Health Care Costs

2014
Factors associated with bronchiolitis obliterans syndrome and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Adult; Allografts; Antilymphocyte Serum; Bronchiolitis Obliterans; Busulfan; Case-Control Studies; C

2014
Fludarabine, cytarabine, granulocyte colony-stimulating factor and melphalan (FALG with L-PAM) as a reduced toxicity conditioning regimen in children with acute leukemia.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; C

2014
Allogeneic hematopoietic SCT for adults AML using i.v. BU in the conditioning regimen: outcomes and risk factors for the occurrence of hepatic sinusoidal obstructive syndrome.
    Bone marrow transplantation, 2014, Volume: 49, Issue:5

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Busulfan; Databases, Factual; Disease-Free Sur

2014
Cytostatic conditioning in experimental allogeneic bone marrow transplantation: Busulfan causes less early gastrointestinal toxicity but Treosulfan results in improved immune reconstitution.
    Immunopharmacology and immunotoxicology, 2014, Volume: 36, Issue:2

    Topics: Animals; B-Lymphocytes; Bone Marrow Transplantation; Busulfan; Cytostatic Agents; Female; Gastrointe

2014
Feasibility of the fludarabine busulfan 3 days and ATG 2 days reduced toxicity conditioning in 51 allogeneic hematopoietic stem cell transplantation: a single-center experience.
    Leukemia research, 2014, Volume: 38, Issue:5

    Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Feasibility Studies; Female; Graft vs Host Disease; Hem

2014
Outcomes of matched sibling donor hematopoietic stem cell transplantation for severe sickle cell disease with myeloablative conditioning and intermediate-dose of rabbit anti-thymocyte globulin.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:9

    Topics: Adolescent; Anemia, Sickle Cell; Animals; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; F

2014
Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.
    Nature medicine, 2014, Volume: 20, Issue:6

    Topics: Animals; Busulfan; Cyclophosphamide; Flow Cytometry; Freund's Adjuvant; Graft vs Host Disease; Hemat

2014
Modified busulfan and cyclophosphamide conditioning regimen for allogeneic hematopoietic stem cell transplantation in the treatment of patients with hematologic malignancies.
    Transplantation proceedings, 2014, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Busulfan; Child; Cyclophosphamide; Female; Graft vs Host Disease; Hematologic Neo

2014
Tolerability and efficacy of busulfan and fludarabine as allogeneic pretransplant conditioning therapy in acute myeloid leukemia: comparison with busulfan and cyclophosphamide regimen.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Femal

2014
The risk of polyomavirus BK-associated hemorrhagic cystitis after allogeneic hematopoietic SCT is associated with myeloablative conditioning, CMV viremia and severe acute GVHD.
    Bone marrow transplantation, 2014, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Aged; BK Virus; Busulfan; Cystitis; Cytomegalovirus Infections; Female; Graft vs

2014
Unrelated CD3/CD19-depleted peripheral stem cell transplantation for Hurler syndrome.
    Pediatric hematology and oncology, 2014, Volume: 31, Issue:8

    Topics: Antigens, CD19; Antineoplastic Agents, Alkylating; Busulfan; CD3 Complex; Chimerism; Drug-Related Si

2014
Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia.
    Bone marrow transplantation, 2014, Volume: 49, Issue:12

    Topics: Adolescent; Anemia, Aplastic; Busulfan; Child; Child, Preschool; Cohort Studies; Cord Blood Stem Cel

2014
[The outcome of thirteen patients with nonmalignant hematologic diseases treated with HLA haploidentical stem cell transplantation].
    Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:6

    Topics: Anemia, Aplastic; Busulfan; Graft vs Host Disease; Hematologic Diseases; Histocompatibility; HLA Ant

2014
Lower dose of antithymocyte globulin does not increase graft-versus-host disease in patients undergoing reduced-intensity conditioning allogeneic hematopoietic stem cell transplant.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:4

    Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Dose-Response Relationship, Drug

2015
Reduced-intensity conditioning for hematopoietic cell transplantation of chronic granulomatous disease.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:2

    Topics: Alemtuzumab; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Busulfan; Child, Preschool; Gr

2015
Treosulfan-based conditioning regimens for allogeneic HSCT in children with acute lymphoblastic leukaemia.
    Annals of hematology, 2015, Volume: 94, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Diarr

2015
Effectiveness and toxicity of high-dose cyclophosphamide in obese versus non-obese patients receiving allogeneic hematopoietic stem cell transplant.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:1

    Topics: Adult; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplant

2016
Incidence and risk factors for cataract after haematopoietic stem cell transplantation for childhood leukaemia: an LEA study.
    British journal of haematology, 2015, Volume: 168, Issue:4

    Topics: Adolescent; Adult; Busulfan; Cataract; Combined Modality Therapy; Dose Fractionation, Radiation; Dos

2015
[Comparing BFA with BuCyA as a myeloablative conditioning regimen for allogeneic stem cell transplantation in acute leukemias].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:4

    Topics: Acute Disease; Busulfan; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Humans; Leukemia, Myel

2014
A well-tolerated regimen of 800 cGy TBI-fludarabine-busulfan-ATG for reliable engraftment after unmanipulated haploidentical peripheral blood stem cell transplantation in adult patients with acute myeloid leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Female; Graft Surviv

2015
Reduced-intensity conditioning with fludarabine and busulfan versus fludarabine and melphalan for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
    Cancer, 2015, Apr-01, Volume: 121, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Fe

2015
Feasible outcomes of T cell-replete haploidentical stem cell transplantation with reduced-intensity conditioning in patients with myelodysplastic syndrome.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:2

    Topics: Acute Disease; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Female; Graft vs Host D

2015
Transplantation for juvenile myelomonocytic leukemia: a retrospective study of 30 children treated with a regimen of busulfan, fludarabine, and melphalan.
    International journal of hematology, 2015, Volume: 101, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; Graft vs

2015
Comparison of a fludarabine and melphalan combination-based reduced toxicity conditioning with myeloablative conditioning by radiation and/or busulfan in acute myeloid leukemia in Japanese children and adolescents.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Combined Modality

2015
Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:6

    Topics: Administration, Intravenous; Adult; Aged; Antineoplastic Agents; Busulfan; Disease-Free Survival; Dr

2015
Clinical comparison of weight- and age-based strategy of dose administration in children receiving intravenous busulfan for hematopoietic stem cell transplantation.
    Pediatric transplantation, 2015, Volume: 19, Issue:3

    Topics: Adolescent; Age Factors; Body Weight; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; F

2015
Pharmacokinetics study of once-daily intravenous busulfan in conditioning regimens for hematopoietic stem cell transplantation.
    International journal of hematology, 2015, Volume: 101, Issue:5

    Topics: Adult; Aged; Area Under Curve; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Tran

2015
Hematopoietic cell transplantation for mucopolysaccharidosis patients is safe and effective: results after implementation of international guidelines.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Acute Disease; Busulfan; Child; Child, Preschool; Chronic Disease; Cord Blood Stem Cell Transplantat

2015
Hematopoietic cell transplantation for mucopolysaccharidosis patients is safe and effective: results after implementation of international guidelines.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Acute Disease; Busulfan; Child; Child, Preschool; Chronic Disease; Cord Blood Stem Cell Transplantat

2015
Hematopoietic cell transplantation for mucopolysaccharidosis patients is safe and effective: results after implementation of international guidelines.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Acute Disease; Busulfan; Child; Child, Preschool; Chronic Disease; Cord Blood Stem Cell Transplantat

2015
Hematopoietic cell transplantation for mucopolysaccharidosis patients is safe and effective: results after implementation of international guidelines.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Acute Disease; Busulfan; Child; Child, Preschool; Chronic Disease; Cord Blood Stem Cell Transplantat

2015
Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in children with sickle cell disease.
    British journal of haematology, 2015, Volume: 169, Issue:5

    Topics: Adolescent; Anemia, Sickle Cell; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Ch

2015
[Establishment of a graft-versus-host disease mouse model for haplo-identical bone marrow transplantation with busulfan and fludarabine conditioning regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:3

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Drug Combinations; Graft vs

2015
Non-total body irradiation myeloablative conditioning with intravenous busulfan and cyclophosphamide in hematopoietic stem cell transplantation for malignant infantile osteopetrosis.
    Pediatric transplantation, 2015, Volume: 19, Issue:4

    Topics: Bone Marrow Cells; Busulfan; Child, Preschool; Chimerism; Combined Modality Therapy; Cyclophosphamid

2015
Higher busulfan dose intensity appears to improve leukemia-free and overall survival in AML allografted in CR2: An analysis from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
    Leukemia research, 2015, Volume: 39, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Busulfan; Female; Graft vs Host Disease; Hematopoiet

2015
Effectiveness of fludarabine- and busulfan-based conditioning regimens in patients with acute myeloblastic leukemia: 8-year experience in a single center.
    Transplantation proceedings, 2015, Volume: 47, Issue:4

    Topics: Adult; Antilymphocyte Serum; Busulfan; Cohort Studies; Cross-Sectional Studies; Disease-Free Surviva

2015
[Combination of busulfan with increased-dose of fludarabine as conditioning regimen for MDS and MDS-AML patients with allo-HSCT].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:6

    Topics: Busulfan; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hum

2015
Mixed T Lymphocyte Chimerism after Allogeneic Hematopoietic Transplantation Is Predictive for Relapse of Acute Myeloid Leukemia and Myelodysplastic Syndromes.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:11

    Topics: Adult; Busulfan; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantat

2015
[Transplant-Related Mortality Following Allogeneic Hematopoietic Stem Cell Transplantation Using Fludarabine/Busulfan-Based Reduced-Intensity Conditioning - A Retrospective Analysis in a Single Institution].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:6

    Topics: Adult; Aged; Allografts; Busulfan; Female; Graft vs Host Disease; Hematologic Diseases; Hematopoieti

2015
Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection.
    American journal of hematology, 2015, Volume: 90, Issue:11

    Topics: Adolescent; Alemtuzumab; Antibodies, Monoclonal, Humanized; Busulfan; Child; Child, Preschool; Cyclo

2015
Comparison of Outcomes for Pediatric Patients With Acute Myeloid Leukemia in Remission and Undergoing Allogeneic Hematopoietic Cell Transplantation With Myeloablative Conditioning Regimens Based on Either Intravenous Busulfan or Total Body Irradiation: A
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:12

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic Stem Cel

2015
HLA haploidentical peripheral blood stem cell transplantation using reduced dose of posttransplantation cyclophosphamide for poor-prognosis or refractory leukemia and myelodysplastic syndrome.
    Experimental hematology, 2015, Volume: 43, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; G

2015
Therapeutic drug monitoring for either oral or intravenous busulfan when combined with pre- and post-transplantation cyclophosphamide.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:3

    Topics: Adult; Aged; Busulfan; Cyclophosphamide; Drug Monitoring; Female; Graft vs Host Disease; Hematologic

2016
European Society for Blood and Marrow Transplantation Analysis of Treosulfan Conditioning Before Hematopoietic Stem Cell Transplantation in Children and Adolescents With Hematological Malignancies.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Blood Transfusion; Bone Marrow Transplantation; Busul

2016
Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation.
    Pharmacogenomics, 2015, Volume: 16, Issue:14

    Topics: Adolescent; Adult; Algorithms; Area Under Curve; Busulfan; Female; Gene Deletion; Genotype; Glutathi

2015
Impact of Thymoglobulin by Stem Cell Source (Peripheral Blood Stem Cell or Bone Marrow) After Myeloablative Stem Cell Transplantation From HLA 10/10-Matched Unrelated Donors: A Report From the Société Française de Greffe de Moelle et de Thérapie Cellulair
    Transplantation, 2016, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Chi-Square Distribut

2016
A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation.
    Bone marrow transplantation, 2016, Volume: 51, Issue:3

    Topics: Acute Disease; Allografts; Animals; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Graf

2016
Treatment of childhood leukemia with haploidentical hematopoietic stem cell transplantation using parent as donor: a single-center study of 111 case.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:22

    Topics: Adolescent; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Graft

2015
[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:12

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Gr

2015
[Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:12

    Topics: Anemia, Aplastic; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Cyclosporine; Disease-Free Survi

2015
TCR-alpha/beta and CD19 depletion and treosulfan-based conditioning regimen in unrelated and haploidentical transplantation in children with acute myeloid leukemia.
    Bone marrow transplantation, 2016, Volume: 51, Issue:5

    Topics: Adolescent; Antigens, CD19; Busulfan; Child; Child, Preschool; Disease-Free Survival; Female; Graft

2016
The efficacy and safety of a new reduced-toxicity conditioning with 4 days of once-daily 100 mg/m(2) intravenous busulfan associated with fludarabine and antithymocyte globulins prior to allogeneic stem cell transplantation in patients with high-risk myel
    Leukemia & lymphoma, 2016, Volume: 57, Issue:10

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Comorbi

2016
[The curative efficacy of unrelated umbilical cord blood stem cells transplantation in intensified myeloablative conditioned patients with acute lymphoblastic leukemia].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclopho

2016
Outcome after Transplantation According to Reduced-Intensity Conditioning Regimen in Patients Undergoing Transplantation for Myelofibrosis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:7

    Topics: Aged; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male

2016
Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies Using a Tailored Busulfan-Based Conditioning Regimen: Single-Center Experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Anemia, Sickle Cell; beta-Thalassemia; Busulfan; Child; Child, Preschool; Chimeri

2016
Does anti-thymocyte globulin have a place in busulfan/fludarabine conditioning for matched related donor hematopoietic stem cell transplantation?
    The Korean journal of internal medicine, 2016, Volume: 31, Issue:4

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Chronic Disease; Disease-Free Survival; Drug T

2016
Pretransplant conditioning with fludarabine and IV busulfan, reduced toxicity and increased safety without compromising antitumor efficacy and overall treatment effect?
    Bone marrow transplantation, 2016, Volume: 51, Issue:7

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2016
[Two Kinds of HLA-mismatched Allogeneic Hematopoictic Stem Cell Transplantation for Treatment of Hematologic Malignancies].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:2

    Topics: Antilymphocyte Serum; Busulfan; Cyclosporine; Graft vs Host Disease; Hematologic Neoplasms; Hematopo

2016
Busulfan-based reduced intensity conditioning regimens for haploidentical transplantation in relapsed/refractory Hodgkin lymphoma: Spanish multicenter experience.
    Bone marrow transplantation, 2016, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hodgkin Disease; Human

2016
Haploidentical, unmanipulated G-CSF-primed peripheral blood stem cell transplantation for high-risk hematologic malignancies: an update.
    Bone marrow transplantation, 2016, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Busulfan; Child; Chimerism; Female; Graft vs Host Disease; Granulocyte Colony-Sti

2016
Long-Term Outcomes after Treatment with Clofarabine ± Fludarabine with Once-Daily Intravenous Busulfan as Pretransplant Conditioning Therapy for Advanced Myeloid Leukemia and Myelodysplastic Syndrome.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:10

    Topics: Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Busulfan; Child; Clofarabine; Female; Gr

2016
Reduced-Intensity Conditioning with Fludarabine, Cyclophosphamide, and Rituximab Is Associated with Improved Outcomes Compared with Fludarabine and Busulfan after Allogeneic Stem Cell Transplantation for B Cell Malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Calcineurin Inhibitors; Cyclo

2016
Fludarabine/Busulfan versus Fludarabine/Melphalan Conditioning in Patients Undergoing Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation for Lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Follow-Up Studies; Graft vs

2016
[Comparison of intensified myeloablative conditioning regime without antithymocytic globulin (ATG) with myeloablative conditioning regime for single-unit unrelated umbilical cord blood transplantation in hematological malignancies].
    Zhonghua yi xue za zhi, 2016, Jul-26, Volume: 96, Issue:28

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; China; Cord Blood Stem

2016
Sequential Intensified Conditioning Regimen Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Intermediate- or High-Risk Acute Myeloid Leukemia in Complete Remission: A Study from the Acute Leukemia Working Party of the European Gr
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Allografts; Amsacrine; Bone Marrow Transplantation; Busulfan; Cyclophospham

2017
Impact of Human Leukocyte Antigen Allele Mismatch in Unrelated Bone Marrow Transplantation with Reduced-Intensity Conditioning Regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Allografts; Bone Marrow Transplantation; Busulfan; Disease-Free Survival; F

2017
Impact of Conditioning Regimen on Outcomes for Children with Acute Myeloid Leukemia Undergoing Transplantation in First Complete Remission. An Analysis on Behalf of the Pediatric Disease Working Party of the European Group for Blood and Marrow Transplanta
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclo

2017
Non-myeloablative conditioning for second hematopoietic cell transplantation for graft failure in patients with non-malignant disorders: a prospective study and review of the literature.
    Bone marrow transplantation, 2017, Volume: 52, Issue:5

    Topics: Adolescent; Adrenoleukodystrophy; Busulfan; Child; Child, Preschool; Graft Rejection; Graft Survival

2017
Comparative Effectiveness of Busulfan and Fludarabine versus Fludarabine and 400 cGy Total Body Irradiation Conditioning Regimens for Acute Myeloid Leukemia/Myelodysplastic Syndrome.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:5

    Topics: Adult; Aged; Busulfan; Erythrocyte Transfusion; Female; Graft vs Host Disease; Humans; Leukemia, Mye

2017
Impact of in vivo T cell depletion in HLA-identical allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission conditioned with a fludarabine iv-busulfan myeloablative regimen: a report from the EBMT Acute Leukemia Working
    Journal of hematology & oncology, 2017, 01-24, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Hematopoieti

2017
Outcomes of children, adolescents, and young adults following allogeneic stem cell transplantation for secondary acute myeloid leukemia and myelodysplastic syndromes-The MD Anderson Cancer Center experience.
    Pediatric transplantation, 2017, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Busulfan; Child; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplan

2017
Incidence and risk factor of hemorrhagic cystitis after allogeneic transplantation with fludarabine, busulfan, and anti-thymocyte globulin myeloablative conditioning.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:3

    Topics: Antilymphocyte Serum; BK Virus; Busulfan; Case-Control Studies; Cystitis; Disease-Free Survival; Dru

2017
Successful outcome of allo-SCT in high-risk pediatric AML using chemotherapy-only conditioning and post transplant immunotherapy.
    Bone marrow transplantation, 2008, Volume: 42, Issue:4

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antine

2008
Outcomes following HSCT using fludarabine, busulfan, and thymoglobulin: a matched comparison to allogeneic transplants conditioned with busulfan and cyclophosphamide.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibodies, Monoclonal; Antilymphocyte Serum; Busulfan; Chro

2008
Umbilical cord-blood transplantations from unrelated donors in patients with inherited metabolic diseases: Single-institute experience.
    Pediatric transplantation, 2008, Volume: 12, Issue:6

    Topics: Administration, Oral; Busulfan; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclophospha

2008
Impact of T cell chimerism on clinical outcome in 117 patients who underwent allogeneic stem cell transplantation with a busulfan-containing reduced-intensity conditioning regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:10

    Topics: Adult; Aged; Busulfan; Graft vs Host Disease; Granulocytes; Hematopoietic Stem Cell Transplantation;

2008
GVHD after chemotherapy conditioning in allogeneic transplanted mice.
    Bone marrow transplantation, 2008, Volume: 42, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan

2008
The use of pharmacokinetic models in paediatric onco-haematology: effects on clinical outcome through the examples of busulfan and cyclosporine.
    Fundamental & clinical pharmacology, 2008, Volume: 22, Issue:6

    Topics: Bayes Theorem; Busulfan; Child; Computer Simulation; Cyclosporine; Drug Administration Schedule; Dru

2008
Study of kidney function impairment after reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation. A single-center experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulf

2009
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:2

    Topics: Adolescent; Area Under Curve; Busulfan; Child; Child, Preschool; Drug Interactions; Graft vs Host Di

2009
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:2

    Topics: Adolescent; Area Under Curve; Busulfan; Child; Child, Preschool; Drug Interactions; Graft vs Host Di

2009
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:2

    Topics: Adolescent; Area Under Curve; Busulfan; Child; Child, Preschool; Drug Interactions; Graft vs Host Di

2009
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:2

    Topics: Adolescent; Area Under Curve; Busulfan; Child; Child, Preschool; Drug Interactions; Graft vs Host Di

2009
Haploidentical in utero hematopoietic cell transplantation improves phenotype and can induce tolerance for postnatal same-donor transplants in the canine leukocyte adhesion deficiency model.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:3

    Topics: Animals; Busulfan; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dogs; Female; Fetal T

2009
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan.
    British journal of haematology, 2009, Volume: 147, Issue:4

    Topics: Adolescent; beta-Thalassemia; Busulfan; Child; Child, Preschool; Drug Evaluation; Female; Graft vs H

2009
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combine

2009
The addition of 400 cGY total body irradiation to a regimen incorporating once-daily intravenous busulfan, fludarabine, and antithymocyte globulin reduces relapse without affecting nonrelapse mortality in acute myelogenous leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2010, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protoco

2010
Reduced-intensity conditioning hematopoietic stem cell transplantation in patients over 60 years: hematologic malignancy outcomes are not impaired in advanced age.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2010, Volume: 16, Issue:6

    Topics: Age Factors; Aged; Aging; Blood Donors; Busulfan; Disease-Free Survival; Female; Graft vs Host Disea

2010
Frequency, risk factors, and outcome of acute kidney injury following bone marrow transplantation at Dr Shariati Hospital in Tehran.
    Iranian journal of kidney diseases, 2010, Volume: 4, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Prescho

2010
Comparison of peripheral blood stem cell transplant with bone marrow transplant in class 3 thalassemic patients.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2010, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

2010
Comparison of donor chimerism following myeloablative and nonmyeloablative allogeneic hematopoietic SCT.
    Bone marrow transplantation, 2011, Volume: 46, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Chimerism; Combined Modality Therapy; Female; Graft Su

2011
The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission.
    Blood, 2010, Jul-22, Volume: 116, Issue:3

    Topics: Adolescent; Adult; Aged; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoies

2010
Order of application and liver toxicity in patients given BU and CY containing conditioning regimens for allogeneic hematopoietic SCT.
    Bone marrow transplantation, 2011, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Aged; Busulfan; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclophos

2011
Long term follow-up of allogeneic stem cell transplantation in patients with myelodysplastic syndromes using busulfan, cytosine arabinoside, and cyclophosphamide.
    American journal of hematology, 2010, Volume: 85, Issue:8

    Topics: Adolescent; Adult; Aged; Busulfan; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Foll

2010
Influence of glutathione S-transferase A1, P1, M1, T1 polymorphisms on oral busulfan pharmacokinetics in children with congenital hemoglobinopathies undergoing hematopoietic stem cell transplantation.
    Pediatric blood & cancer, 2010, Dec-01, Volume: 55, Issue:6

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Case-Control Studies;

2010
Individualized intervention guided by BCR-ABL transcript levels after HLA-identical sibling donor transplantation improves HSCT outcomes for patients with chronic myeloid leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Benzamides; Busulfan; Child; Cyclophosphamide; Female; Fusion Proteins, bcr-abl;

2011
Targeted i.v. BU and fludarabine (t-i.v. BU/Flu) provides effective control of AML in adults with reduced toxicity.
    Bone marrow transplantation, 2011, Volume: 46, Issue:5

    Topics: Adult; Aged; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Injec

2011
Evaluating the impact of antithymocyte globulin on lung function at 1 year after allogeneic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:5

    Topics: Administration, Oral; Adult; Animals; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Female; Forc

2011
Feasibility of reduced-intensity cord blood transplantation as salvage therapy for graft failure: results of a nationwide survey of adult patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:6

    Topics: Adult; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Disease-Free Survival; Fema

2011
Reduced-intensity conditioning with Fludarabin, oral Busulfan, and thymoglobulin allows long-term disease control and low transplant-related mortality in patients with hematological malignancies.
    Experimental hematology, 2010, Volume: 38, Issue:12

    Topics: Adolescent; Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Dis

2010
Association of busulfan and cyclophosphamide conditioning with sleep disorders after hematopoietic stem cell transplantation.
    Acta haematologica, 2010, Volume: 124, Issue:2

    Topics: Adult; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematologic Neoplasms; Hematopoiet

2010
Influence of comorbidities on transplant outcomes in patients aged 50 years or more after myeloablative conditioning incorporating fludarabine, BU and ATG.
    Bone marrow transplantation, 2011, Volume: 46, Issue:8

    Topics: Age Factors; Aged; Antilymphocyte Serum; Busulfan; Comorbidity; Disease-Free Survival; Female; Graft

2011
Unrelated donor transplantation for acute myelogenous leukemia in first remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow

2011
Effect of splenectomy on pancytopenia after a peripheral blood stem cell transplantation.
    Cell transplantation, 2011, Volume: 20, Issue:7

    Topics: Adult; Busulfan; Cyclophosphamide; Dexamethasone; Female; Graft Survival; Graft vs Host Disease; Hem

2011
Bronchiolitis obliterans syndrome epidemiology after allogeneic hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Bone Marrow Transplantation; Bronchiolitis Obliterans; Busulfan; Chronic Di

2011
Increasing the dose intensity of the conditioning regimen prior to allogeneic hematopoietic stem cell transplant: the role of pharmacokinetic monitoring.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:12

    Topics: Busulfan; Dose-Response Relationship, Drug; Graft vs Host Disease; Hematologic Neoplasms; Hematopoie

2010
Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.
    Clinical & developmental immunology, 2010, Volume: 2010

    Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; CD8-Positive T-Lymphocytes; Cyclophosphamide;

2010
Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience.
    Blood, 2011, Apr-21, Volume: 117, Issue:16

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Chimerism; Cohort

2011
Imatinib combined with myeloablative allogeneic hematopoietic stem cell transplantation for advanced phases of chronic myeloid leukemia.
    Leukemia research, 2011, Volume: 35, Issue:10

    Topics: Adult; Benzamides; Blast Crisis; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cyclosporine

2011
Higher busulfan dose intensity does not improve outcomes of patients undergoing allogeneic haematopoietic cell transplantation following fludarabine, busulfan-based reduced toxicity conditioning.
    Hematological oncology, 2011, Volume: 29, Issue:4

    Topics: Adult; Aged; Busulfan; Chimerism; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplanta

2011
Allogeneic haematopoietic stem cell transplantation as therapy for chronic granulomatous disease--single centre experience.
    Journal of clinical immunology, 2011, Volume: 31, Issue:3

    Topics: Adolescent; Antigens, CD; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease

2011
Reduced-intensity conditioning by fludarabine/busulfan without additional irradiation or T-cell depletion leads to low non-relapse mortality in unrelated bone marrow transplantation.
    International journal of hematology, 2011, Volume: 93, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Chimerism; Female; Graft

2011
Idarubicin-intensified BUCY2 regimens may lower relapse rate and improve survival in patients undergoing allo-SCT for high-risk hematological malignancies: a retrospective analysis.
    Bone marrow transplantation, 2012, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Chimerism; Combined Mod

2012
Long-term results of placental blood allografting using reduced-intensity conditioning: multicenter experience in a developing country.
    Hematology (Amsterdam, Netherlands), 2011, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Busulfan; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Cy

2011
Allogeneic hematopoietic cell transplant for peripheral T-cell non-Hodgkin lymphoma results in long-term disease control.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosp

2011
Alemtuzumab based reduced intensity conditioning allogeneic haematopoietic stem cell transplantation for myelofibrosis.
    Leukemia research, 2011, Volume: 35, Issue:8

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antine

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Reduced-intensity conditioning therapy with busulfan, fludarabine, and antithymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Femal

2011
Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI.
    Oral diseases, 2011, Volume: 17, Issue:7

    Topics: Adolescent; Age Factors; Anemia, Aplastic; Area Under Curve; Busulfan; Cyclophosphamide; Dose Fracti

2011
Long-term results of allogeneic hematopoietic stem cell transplantation after reduced-intensity conditioning with busulfan, fludarabine, and antithymocyte globulin.
    Neoplasma, 2011, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Cohort Studies; Drug Therapy, Combination;

2011
Comparable outcome after related or unrelated allogeneic stem cell transplant following reduced conditioning with fludarabine, busulfan and antithymocyte globulin.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:1

    Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell

2012
A comparison of immune reconstitution and graft-versus-host disease following myeloablative conditioning versus reduced toxicity conditioning and umbilical cord blood transplantation in paediatric recipients.
    British journal of haematology, 2011, Volume: 155, Issue:2

    Topics: Alemtuzumab; Antibiotic Prophylaxis; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antily

2011
[Conditioning regimen of allogeneic hematopoietic stem cell transplantation for aplastic anemia in Japan].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Female;

2011
Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.
    International journal of clinical and experimental pathology, 2011, Aug-15, Volume: 4, Issue:6

    Topics: Animals; Apoptosis; Bone Marrow Transplantation; Busulfan; Cell Transplantation; Cyclophosphamide; D

2011
The increase from 2.5 to 5 mg/kg of rabbit anti-thymocyte-globulin dose in reduced intensity conditioning reduces acute and chronic GVHD for patients with myeloid malignancies undergoing allo-SCT.
    Bone marrow transplantation, 2012, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Antilymphocyte Serum; Busulfan; Graft vs Host Disease; Hematopoiet

2012
Keratinocyte dysplasia in hematopoietic stem cell transplantation recipients in the day-28-to-84 posttransplantation period.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:8

    Topics: Biopsy; Busulfan; Case-Control Studies; Female; Graft vs Host Disease; Hematopoietic Stem Cell Trans

2012
Comparison of new flu-bu12-tg conditioning with the standard bu-cy myeloablative regimen in patients undergoing allogeneic stem cell transplantation for acute myeloid leukemia.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2011, Volume: 155, Issue:4

    Topics: Adult; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Graft vs Hos

2011
The outcome of allogeneic hematopoietic stem cell transplants without total body irradiation in pediatric patients with acute lymphoblastic leukemia: single centre experience.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Free

2012
Feasibility of non-TBI conditioning with busulfan and fludarabine for allogeneic stem cell transplantation in lymphoid malignancy.
    The Korean journal of internal medicine, 2012, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Busulfan; Chi-Square Distribution; Disease-Free Survival; Drug Therapy, Combinati

2012
Treosulphan-based radiation-free myeloablative conditioning for allogeneic transplant in infant acute lymphoblastic leukaemia.
    British journal of haematology, 2012, Volume: 159, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; H

2012
Allo-SCT using BU, CY and melphalan for children with AML in second CR.
    Bone marrow transplantation, 2013, Volume: 48, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cohor

2013
Treosulfan-thiotepa-fludarabine-based conditioning regimen for allogeneic transplantation in patients with thalassemia major: a single-center experience from north India.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:3

    Topics: Adolescent; beta-Thalassemia; Busulfan; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host

2013
Allo-HSCT for acute leukemia of ambiguous lineage in adults: the comparison between standard conditioning and intensified conditioning regimens.
    Annals of hematology, 2013, Volume: 92, Issue:5

    Topics: Adolescent; Adult; Busulfan; Child; Cyclophosphamide; Cytarabine; Etoposide; Female; Graft vs Host D

2013
Prognostic impact of immune status and hematopoietic recovery before and after fludarabine, IV busulfan, and antithymocyte globulins (FB2 regimen) reduced-intensity conditioning regimen (RIC) allogeneic stem cell transplantation (allo-SCT).
    European journal of haematology, 2013, Volume: 90, Issue:3

    Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; H

2013
[Application of FBC conditioning regimen in HLA haplotype peripheral blood stem cell transplantation].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2002, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Female; Graft Survival; Graft vs Host Disease; Hemato

2002
Non-myeloablative haematopoietic stem cell transplantation for severe aplastic anaemia with various complications.
    Clinical and laboratory haematology, 2002, Volume: 24, Issue:5

    Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Busulfan; Female; Fractures, Bone; Graft Rejection; G

2002
The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation.
    Blood, 2002, Nov-01, Volume: 100, Issue:9

    Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo

2002
Nonmyeloablative allogeneic stem cell transplantation for the treatment of chronic myeloid leukemia in first chronic phase.
    Blood, 2003, Jan-15, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool

2003
BU-CTX(2) as conditioning regimen for allogeneic hematopoietic stem cell transplantation in sixty patients with leukemia.
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2002, Volume: 23, Issue:7

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Transplantation Co

2002
Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.
    British journal of haematology, 2002, Volume: 119, Issue:3

    Topics: Adult; Busulfan; Dose-Response Relationship, Drug; Female; Graft vs Host Disease; Hematopoietic Stem

2002
Reduced non-relapse mortality after reduced intensity conditioning in advanced chronic lymphocytic leukemia.
    Annals of hematology, 2002, Volume: 81 Suppl 2

    Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive

2002
Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2003, Volume: 31, Issue:2

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Follo

2003
Successful unrelated cord blood transplantation in two children with severe combined immunodeficiency syndrome.
    Bone marrow transplantation, 2003, Volume: 31, Issue:2

    Topics: Antilymphocyte Serum; Busulfan; Cyclosporine; Fetal Blood; Gastroenteritis; Graft vs Host Disease; H

2003
Graft-versus-host disease following allogeneic transplantation from HLA-identical sibling with antithymocyte globulin-based reduced-intensity preparative regimen.
    Blood, 2003, Jul-15, Volume: 102, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Antilymphocyte Serum; Busulfan; Chronic Disease; Disease Progressi

2003
Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation.
    Blood, 2003, Jul-15, Volume: 102, Issue:2

    Topics: Aged; Bone Marrow Transplantation; Busulfan; Cause of Death; Cyclosporine; Female; Graft vs Host Dis

2003
The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Busulfan; Drug Interactions; Female; Graft vs Host Disease; Hematopoietic Stem Ce

2003
Impact of graft-versus-host disease in reduced-intensity stem cell transplantation (RIST) for patients with haematological malignancies.
    British journal of haematology, 2003, Volume: 121, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Busulfan; Chronic Disease; Cladribine; Cyclophosphamide; Dis

2003
Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: myeloablation with reduced toxicity.
    Experimental hematology, 2003, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic S

2003
Evidence of a graft-versus-leukemia effect in chronic lymphocytic leukemia after reduced-intensity conditioning and allogeneic stem-cell transplantation: the Cooperative German Transplant Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-15, Volume: 21, Issue:14

    Topics: Adult; Aged; Busulfan; Child; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Graf

2003
Reduced-intensity preparative regimen and allogeneic stem cell transplantation for advanced solid tumors.
    Blood, 2004, Jan-15, Volume: 103, Issue:2

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Chronic Disease;

2004
Successful engraftment of HLA-haploidentical related transplants using nonmyeloablative conditioning with fludarabine, busulfan and anti-T-lymphocyte globulin.
    Leukemia, 2003, Volume: 17, Issue:10

    Topics: Antilymphocyte Serum; Busulfan; Female; Graft vs Host Disease; Histocompatibility Testing; HLA Antig

2003
Fludarabine and once-daily intravenous busulfan for allogeneic bone marrow transplantation for Chediak-Higashi syndrome.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:10

    Topics: Bone Marrow Transplantation; Busulfan; Chediak-Higashi Syndrome; Child, Preschool; Graft vs Host Dis

2003
Late hemorrhagic cystitis after reduced-intensity hematopoietic stem cell transplantation (RIST).
    Bone marrow transplantation, 2003, Volume: 32, Issue:11

    Topics: Adenoviridae; Adolescent; Adult; Aged; Antibodies, Viral; Busulfan; Child; Child, Preschool; Cystiti

2003
Allogeneic peripheral blood stem cell transplantation following fludarabine-based conditioning in six children with advanced Hodgkin's disease.
    Annals of hematology, 2004, Volume: 83, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Busulfan; Child; Combined Modality Therapy; Cyclophosphamide; Dis

2004
Cyclosporin A-associated status epilepticus related to hematopoietic stem cell transplantation for thalassemia.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:6

    Topics: Anticonvulsants; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease Suscepti

2003
Reduced-intensity conditioning with busulfan and fludarabine with or without antithymocyte globulin in HLA-identical sibling transplantation--a retrospective analysis.
    Bone marrow transplantation, 2004, Volume: 33, Issue:5

    Topics: Acute Disease; Adult; Aged; Antilymphocyte Serum; Busulfan; Chronic Disease; Combined Modality Thera

2004
Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Apr-01, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Body Mass Index; Busulfan; Cyclophosphamide; Female; Genotype; Graft vs Host Dise

2004
Once-daily intravenous busulfan and fludarabine: clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS.
    Blood, 2004, Aug-01, Volume: 104, Issue:3

    Topics: Adult; Aged; Busulfan; Female; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosupp

2004
Addition of treosulfan to a nonmyeloablative conditioning regimen results in enhanced chimerism and immunologic tolerance in an experimental allogeneic bone marrow transplant model.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2004, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Transplantation; Busulfan; Dose

2004
[Reduced intensity stem cell transplantation for metastatic renal cell carcinoma].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2004, Volume: 95, Issue:3

    Topics: Adult; Busulfan; Carcinoma, Renal Cell; Cyclosporine; Fatal Outcome; Female; Graft vs Host Disease;

2004
Outcome of single fraction total body irradiation-conditioned stem cell transplantation in younger children with malignant disease--comparison with a busulphan-cyclophosphamide regimen.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:2

    Topics: Busulfan; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Graft vs Hos

2004
Effects of allogeneic bone marrow transplantation on pulmonary function in 80 children in a single paediatric centre.
    Bone marrow transplantation, 2004, Volume: 34, Issue:2

    Topics: Adolescent; Airway Obstruction; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyto

2004
Intravenous busulfan as preparative regimen in pediatric patients receiving hematopoietic stem cell transplantation: the preliminary experience in Taiwan.
    Journal of the Chinese Medical Association : JCMA, 2004, Volume: 67, Issue:3

    Topics: Adolescent; Busulfan; Child; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation;

2004
Low transplant-related mortality with allogeneic stem cell transplantation in elderly patients.
    Bone marrow transplantation, 2004, Volume: 34, Issue:2

    Topics: Aged; Busulfan; Feasibility Studies; Female; Graft Survival; Graft vs Host Disease; Hematologic Neop

2004
Conditioning regimens including high-dose busulfan cause a high incidence of transplant-related mortality after myeloablative stem cell transplantation.
    Chemotherapy, 2004, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Female; Graft vs Host Disease; Healt

2004
Nonmyeloablative stem cell transplantation in patients with ALL and AML results in low nonrelapse mortality despite high rate of infections and GVHD.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5, Issue:5

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Contraindications; Cyclosporine; Female; Follo

2004
Pilot study of reduced-intensity conditioning followed by allogeneic stem cell transplantation from related and unrelated donors in patients with myelofibrosis.
    British journal of haematology, 2005, Volume: 128, Issue:5

    Topics: Adult; Antilymphocyte Serum; Blood Transfusion, Autologous; Busulfan; Disease-Free Survival; Female;

2005
Comparison of ARF after myeloablative and nonmyeloablative hematopoietic cell transplantation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Busulfan; Cohort Studies; Comorbidity; Cyclophosphamid

2005
Nephrotic syndrome in patients with peripheral blood stem cell transplant.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:4

    Topics: Acute Kidney Injury; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineop

2005
Rabbit-immunoglobulin G levels in patients receiving thymoglobulin as part of conditioning before unrelated donor stem cell transplantation.
    Haematologica, 2005, Volume: 90, Issue:7

    Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Busulfan; Child; Child, Pr

2005
Extracorporeal photo-chemotherapy for graft-versus-host disease.
    Haematologica, 2005, Volume: 90, Issue:8

    Topics: Busulfan; Graft vs Host Disease; Hematologic Neoplasms; Humans; Leukemia; Lymphoma, Non-Hodgkin; Pho

2005
Extracorporeal chemophototherapy for the treatment of graft-versus-host disease: hematologic consequences of short-term, intensive courses.
    Haematologica, 2005, Volume: 90, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Busulfan; Female; Graft vs Host Disease; Hematologic

2005
[Allogeneic blood stem cell transplantation in high-risk patients after conditioning with treosulfan and fludarabine].
    Deutsche medizinische Wochenschrift (1946), 2005, Sep-23, Volume: 130, Issue:38

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; Disease-Free Survival; Do

2005
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.
    Bone marrow transplantation, 2006, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Blast Crisis; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Free S

2006
Bone marrow transplantation from matched related donors for patients with Fanconi anemia using low-dose busulfan and cyclophosphamide as conditioning.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

2006
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical

2005
Allogeneic haematopoietic cell transplantation for chronic myelogenous leukaemia in the era of imatinib: a retrospective multicentre study.
    European journal of haematology, 2006, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Benzamides; Busulfan; Cohort Studies; Combined Modality Th

2006
Simultaneous control of third-degree graft-versus-host disease and prevention of recurrence of juvenile myelomonocytic leukemia (JMML) with 6-mercaptopurine following fulminant JMML relapse early after KIR-mismatched bone marrow transplantation.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:12

    Topics: Antimetabolites, Antineoplastic; Busulfan; Cyclophosphamide; Graft vs Host Disease; Graft vs Leukemi

2005
Conditioning including antithymocyte globulin followed by unmanipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes with HLA-identical sibling transplantation.
    Blood, 2006, Apr-15, Volume: 107, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protoco

2006
The outcome of children with acute myeloid leukemia (AML) post-allogeneic stem cell transplantation (SCT) is not improved by the addition of etoposide to the conditioning regimen.
    Pediatric blood & cancer, 2006, Volume: 47, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclo

2006
Effect of IL-18 and sIL2R on aGVHD occurrence after hematopoietic stem cell transplantation in some Iranian patients.
    Transplant immunology, 2006, Volume: 15, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Biomarkers; Busulfan; Child; Child, Preschool; Cyclophosphamide; F

2006
Allografting in patients with severe, refractory aplastic anemia using peripheral blood stem cells and a fludarabine-based conditioning regimen: the Mexican experience.
    American journal of hematology, 2006, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cycl

2006
Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:6

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Female; Fibrosis; Graf

2006
Risk factor analysis for thrombotic microangiopathy after reduced-intensity or myeloablative allogeneic hematopoietic stem cell transplantation.
    American journal of hematology, 2006, Volume: 81, Issue:7

    Topics: Adolescent; Adult; Aged; Busulfan; Disease-Free Survival; Evaluation Studies as Topic; Female; Graft

2006
Serial transplantation resulting in tolerance to an unrelated cord blood graft.
    Transplantation, 2006, Jun-15, Volume: 81, Issue:11

    Topics: Antilymphocyte Serum; B-Lymphocytes; Bone Marrow Transplantation; Busulfan; Chimerism; Cord Blood St

2006
Fludarabine-based reduced intensity conditioning for stem cell transplantation of Fanconi anemia patients from fully matched related and unrelated donors.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:7

    Topics: Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm;

2006
Different outcome of allogeneic transplantation in myelofibrosis using conventional or reduced-intensity conditioning regimens.
    British journal of haematology, 2006, Volume: 135, Issue:3

    Topics: Adult; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Child, Preschool; Cyclophosphamide; Fe

2006
Clinical outcomes and direct hospital costs of reduced-intensity allogeneic transplantation in chronic myeloid leukemia.
    Bone marrow transplantation, 2006, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; C

2006
Impact of conditioning regimen intensity on outcome of allogeneic hematopoietic cell transplantation for advanced acute myelogenous leukemia and myelodysplastic syndrome.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:10

    Topics: Acute Disease; Adult; Aged; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Graft S

2006
Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced chronic lymphocytic leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Di

2006
Apoptotic donor leukocytes limit mixed-chimerism induced by CD40-CD154 blockade in allogeneic bone marrow transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Animals; Animals, Congenic; Antibodies, Monoclonal; Apoptosis; Bone Marrow Transplantation; Busulfan

2006
Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Cause of Death; Cohort Studies; Cyclophosphamide; Disease-Free Su

2006
Reduced-toxicity conditioning with fludarabine and treosulfan prior to allogeneic stem cell transplantation in multiple myeloma.
    Bone marrow transplantation, 2007, Volume: 39, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; Disease-Free Surviv

2007
Successful reduced-intensity stem cell transplantation in a patient with myelodysplastic syndrome combined with Sweet's syndrome.
    Hematology (Amsterdam, Netherlands), 2006, Volume: 11, Issue:3

    Topics: Aclarubicin; Anemia, Refractory, with Excess of Blasts; Anti-Inflammatory Agents; Bone Marrow Transp

2006
Alloimmune hepatitis following peripheral stem cell transplantation.
    Bone marrow transplantation, 2007, Volume: 39, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Busulfan; Cyclophosphamide; Female; Graft vs Host Dis

2007
Modified conditioning regimen busulfan-cyclophosphamide followed by allogeneic stem cell transplantation in patients with multiple myeloma.
    Chinese medical journal, 2007, Mar-20, Volume: 120, Issue:6

    Topics: Adult; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplant

2007
Clinical features and risk factors of pure red cell aplasia following major ABO-incompatible allogeneic hematopoietic stem cell transplantation.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:2

    Topics: ABO Blood-Group System; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antig

2007
Fludarabine and busulfan as a myeloablative conditioning regimen for allogeneic stem cell transplantation in high- and standard-risk leukemic patients.
    Bone marrow transplantation, 2007, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Busulfan; Child; Disease-Free Survival; Female; Graft Survival; Graft vs Host Dis

2007
Engraftment kinetics and hematopoietic chimerism after reduced-intensity conditioning with fludarabine and treosulfan before allogeneic stem cell transplantation.
    Annals of hematology, 2007, Volume: 86, Issue:8

    Topics: Adolescent; Adult; Aged; Busulfan; Chimerism; Female; Graft Survival; Graft vs Host Disease; Hematol

2007
Unrelated-donor bone marrow transplantation with a conditioning regimen including fludarabine, busulfan, and 4 Gy total body irradiation.
    International journal of hematology, 2007, Volume: 85, Issue:3

    Topics: Adult; Aged; Bone Marrow Transplantation; Busulfan; Female; Graft Survival; Graft vs Host Disease; H

2007
Long-term outcomes after reduced-intensity conditioning allogeneic stem cell transplantation for low-grade lymphoma: a survey by the French Society of Bone Marrow Graft Transplantation and Cellular Therapy (SFGM-TC).
    Haematologica, 2007, Volume: 92, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Prot

2007
Treosulfan, cyclophosphamide and antithymocyte globulin for allogeneic hematopoietic cell transplantation in acquired severe aplastic anemia.
    Annals of transplantation, 2006, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Disease-Free

2006
Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2007, Volume: 13, Issue:7

    Topics: Adolescent; Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Cy

2007
Characterization of graft-versus-leukemia responses in patients treated for advanced chronic lymphocytic leukemia with donor lymphocyte infusions after in vitro T-cell depleted allogeneic stem cell transplantation following reduced-intensity conditioning.
    Leukemia, 2007, Volume: 21, Issue:12

    Topics: Adolescent; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neop

2007
New myeloablative conditioning regimen with fludarabine and busulfan for allogeneic stem cell transplantation: comparison with BuCy2.
    Bone marrow transplantation, 2007, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Arterial Occlusive Diseases; Busulfan; Cyclophosphamide; Cytomegalovirus Infectio

2007
Comparison between two fludarabine-based reduced-intensity conditioning regimens before allogeneic hematopoietic stem-cell transplantation: fludarabine/melphalan is associated with higher incidence of acute graft-versus-host disease and non-relapse mortal
    Leukemia, 2007, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Graft vs

2007
[Efficacy and toxicity of intravenous busulfan-based conditioning before allogeneic peripheral blood stem cell transplantation for leukemia].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Female; Follow-Up Studies; Graft vs Host Disease; Hum

2007
Allogeneic hemopoietic stem cell transplantation (HSCT) for Wiskott-Aldrich syndrome: a report of the Spanish Working Party for Blood and Marrow Transplantation in Children (GETMON).
    Pediatric hematology and oncology, 2007, Volume: 24, Issue:6

    Topics: Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Graft vs Ho

2007
[Allogenic transplantation of hemopoietic stem cells in low-intensity regimes in patients with hematological malignancies].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Busulfan; Female; Graft vs Host Disease; Hematologic Neoplas

2007
Allogeneic stem cell transplantation from matched related and unrelated donors in thalassemia major patients using a reduced toxicity fludarabine-based regimen.
    Bone marrow transplantation, 2007, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Antilymphocyte Serum; beta-Thalassemia; Busulfan; Child; Child, Preschool; Female

2007
Comparison of myeloablative and nonmyeloablative hematopoietic stem cell transplantation for treatment of chronic myeloid leukemia.
    International journal of hematology, 2007, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antilymphocyte Serum; Busulfan; Child; Disease-Free Survival; Female

2007
Fludarabine and treosulfan: a novel modified myeloablative regimen for allogeneic hematopoietic stem-cell transplantation with effective antileukemia activity in patients with acute myeloid leukemia and myelodysplastic syndromes.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:12

    Topics: Adult; Aged; Busulfan; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Human

2007
Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Feb-01, Volume: 26, Issue:4

    Topics: Adult; Aged; Busulfan; Chronic Disease; Disease-Free Survival; Drug Therapy, Combination; Female; Gr

2008
Graft-versus-myeloma effects in reduced-intensity cord blood transplantation.
    International journal of hematology, 2007, Volume: 86, Issue:5

    Topics: Aged; Busulfan; Cord Blood Stem Cell Transplantation; Disease-Free Survival; Female; Graft Survival;

2007
Infectious complications in chronic graft-versus-host disease: a retrospective study of 145 recipients of allogeneic hematopoietic stem cell transplantation with reduced- and conventional-intensity conditioning regimens.
    Transplant infectious disease : an official journal of the Transplantation Society, 2008, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aged; Aspergillosis; Bacteremia; Busulfan; Catheterization, Central Venous; Chron

2008
Peripheral blood versus bone marrow as a source of hematopoietic stem cells for allogeneic transplantation in children with class I and II beta thalassemia major.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:3

    Topics: Acute Disease; Adolescent; beta-Thalassemia; Blood Platelets; Bone Marrow Transplantation; Busulfan;

2008
Defibrotide in the prevention and treatment of veno-occlusive disease in autologous and allogeneic stem cell transplantation in children.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:4

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Female; Fibrinolytic Agents; Graft vs Host Disease; H

2008
Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transplantation for hematological malignancies: a 10-year retrospective analysis from the Société Française de Greffe de Moelle et de Thérapie Cellulaire.
    Experimental hematology, 2008, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Disease-Free Survi

2008
Characterization of acute graft-versus-host disease following reduced-intensity stem-cell transplantation from an HLA-identical related donor.
    American journal of hematology, 2008, Volume: 83, Issue:8

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Busulfan; Cladribine; Dis

2008
Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide.
    The New England journal of medicine, 1983, Dec-01, Volume: 309, Issue:22

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Busulfan; Child; Combine

1983
Pulmonary complications of bone marrow transplantation: a comparison of total body irradiation and cyclophosphamide to busulfan and cyclophosphamide.
    International journal of radiation oncology, biology, physics, 1995, Apr-30, Volume: 32, Issue:1

    Topics: Actuarial Analysis; Adolescent; Adult; Bleomycin; Bone Marrow Transplantation; Busulfan; Child; Chil

1995
Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Alopecia; Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Child; Child,

1995
Functional hyperactivity of monocytes after bone marrow transplantation: possible relevance for the development of post-transplant complications or relapse.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biopterins; Bone Marr

1995
Extramedullary toxicity of a conditioning regimen containing busulphan, cyclophosphamide and etoposide in 84 patients undergoing autologous and allogenic bone marrow transplantation.
    Bone marrow transplantation, 1995, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Transplantati

1995
Treatment of Omenn syndrome by bone marrow transplantation.
    The Journal of pediatrics, 1995, Volume: 127, Issue:1

    Topics: Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Graft Reje

1995
Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Actuarial Analysis; Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cycl

1995
The effects of bone marrow transplantation on pulmonary function in children.
    Pediatric pulmonology, 1994, Volume: 18, Issue:6

    Topics: Adolescent; Age Factors; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cytomegalov

1994
Reconstitution of lymphocyte subsets after peripheral blood stem cell transplantation: two-color flow cytometric analysis.
    Bone marrow transplantation, 1994, Volume: 13, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Blood Component Transfusion; Busulfan; Combined Modality Therapy;

1994
Bone marrow transplantation in Iran.
    Bone marrow transplantation, 1994, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Anemia, Aplastic; beta-Thalassemia; Bone Marrow Transplantation; Busulfan; Child;

1994
Eosinophilia after allogeneic bone marrow transplantation using the busulfan and cyclophosphamide preparative regimen.
    Bone marrow transplantation, 1994, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Chronic Disease; Cyclophosphamide; Eosinop

1994
Allogeneic bone marrow transplantation combined with multiple anti-HIV-1 treatment in a case of AIDS.
    Bone marrow transplantation, 1993, Volume: 12, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Busulf

1993
Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice.
    Blood, 1994, Apr-15, Volume: 83, Issue:8

    Topics: Acute Disease; Animals; Busulfan; Cell Transplantation; Chronic Disease; Cyclophosphamide; Cytokines

1994
Allogeneic bone marrow transplantation for children with acute myeloblastic leukemia in first complete remission: impact of conditioning regimen without total-body irradiation--a report from the Société Française de Greffe de Moelle.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child,

1994
Factors affecting hair regrowth after bone marrow transplantation.
    Bone marrow transplantation, 1993, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Age Factors; Alopecia; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan

1993
Bronchiolitis obliterans after bone marrow transplantation: the effect of preconditioning.
    Respiration; international review of thoracic diseases, 1993, Volume: 60, Issue:2

    Topics: Adult; Bone Marrow Transplantation; Bronchiolitis Obliterans; Busulfan; Cyclophosphamide; Female; Gr

1993
Bone marrow transplantation (BMT) in 14 children with severe sickle cell disease (SCD): the French experience. GEGMO.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Adolescent; Africa; Anemia, Sickle Cell; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan;

1993
Bone marrow transplantation in thalassemia. The Cagliari team experience.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Adolescent; Adult; beta-Thalassemia; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Chi

1993
Bone marrow transplantation in class 2 thalassemia patients.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Adolescent; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyc

1993
Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine after busulfan and cyclophosphamide in patients with hematologic malignancies.
    Blood, 1993, Feb-01, Volume: 81, Issue:3

    Topics: Adult; Busulfan; Chronic Disease; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Female;

1993
Successful allogeneic bone marrow transplantation in juvenile CML: conditioning or graft-versus-leukaemia effect?
    Bone marrow transplantation, 1993, Volume: 11, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclophospham

1993
Busulfan-based regimens and allogeneic bone marrow transplantation in patients with myelodysplastic syndromes.
    Blood, 1993, Apr-15, Volume: 81, Issue:8

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Chromosome Aberra

1993
Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients.
    Blood, 1996, Jan-01, Volume: 87, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Child; Child, Pres

1996
The origin of IgG production and homogeneous IgG components after allogeneic bone marrow transplantation.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Anemia, Aplastic; B-Lymphocytes; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Survival;

1996
Long-term leukemia-free survival after allogeneic marrow transplantation in patients with acute myelogenous leukemia.
    Annals of hematology, 1996, Volume: 72, Issue:2

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Disease

1996
Study of hematopoietic progenitor cells in thalassemia after bone marrow transplantation.
    The Southeast Asian journal of tropical medicine and public health, 1995, Volume: 26 Suppl 1

    Topics: beta-Thalassemia; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cells, Cultured; Child; Child,

1995
Transplantation of allogeneic peripheral blood progenitor cells--the EBMT experience.
    Bone marrow transplantation, 1996, Volume: 17 Suppl 2

    Topics: Adolescent; Adult; Blood Donors; Busulfan; Child; Child, Preschool; Cyclosporine; Erythropoietin; Fe

1996
Unrelated donor bone marrow transplantation without T cell depletion using a chemotherapy only condition regimen. Low incidence of failed engraftment and severe acute GVHD.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Actuarial Analysis; Acute Disease; Adult; Anti-Infective Agents; Bone Marrow Transplantation; Busulf

1996
High incidence of chronic GVHD after primary allogeneic peripheral blood stem cell transplantation in patients with hematologic malignancies.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Adult; Busulfan; Chimera; Cyclophosphamide; Female; Graft vs Host Disease; Hematologic Neoplasms; He

1996
Unrelated allogeneic bone marrow transplantation using high-dose busulfan and cyclophosphamide (BU-CY) for the preparative regimen.
    Bone marrow transplantation, 1996, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

1996
CsA-associated neurotoxicity and ineffective prophylaxis with clonazepam in patients transplanted for thalassemia major: analysis of risk factors.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; beta-Thalassemia; Blood

1996
Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bone Marrow Transplantation; Busulfan; Child; Child,

1996
Eosinophilia after allogeneic bone marrow transplantation using busulfan and cyclophosphamide conditioning regimen.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Bone Marrow Transplantation; Busulfan; Chronic Disease; Cyclophosphamide; Eosinophilia; Graft vs Hos

1996
Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome.
    Blood, 1996, Oct-01, Volume: 88, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Bone Marrow Transplanta

1996
A pilot study of busulfan and melphalan as preparatory regimen prior to allogeneic bone marrow transplantation in refractory or relapsed hematological malignancies.
    Bone marrow transplantation, 1996, Volume: 18, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Female

1996
Influence of graft-versus-host disease on outcome following allogeneic transplantation with radiation-free preparative therapy in patients with advanced leukemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Moda

1996
Neurologic complications after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1996, Volume: 18, Issue:6

    Topics: Bone Marrow Transplantation; Brain Abscess; Busulfan; Cerebrovascular Disorders; Cyclosporine; Encep

1996
Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Cyclophosphamide; Female; Graft Reject

1997
Busulfan/cyclophosphamide in volunteer unrelated donor (VUD) BMT: excellent feasibility and low incidence of treatment-related toxicity.
    Bone marrow transplantation, 1997, Volume: 19, Issue:12

    Topics: Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine;

1997
Hepatic veno-occlusive disease after myeloablative treatment and bone marrow transplantation: value of gray-scale and Doppler US in 100 patients.
    Radiology, 1997, Volume: 204, Issue:2

    Topics: Adult; Busulfan; Child; Diagnosis, Differential; Female; Graft vs Host Disease; Hematopoietic Stem C

1997
Hepatic veno-occlusive disease after myeloablative treatment and bone marrow transplantation: value of gray-scale and Doppler US in 100 patients.
    Radiology, 1997, Volume: 204, Issue:2

    Topics: Adult; Busulfan; Child; Diagnosis, Differential; Female; Graft vs Host Disease; Hematopoietic Stem C

1997
Hepatic veno-occlusive disease after myeloablative treatment and bone marrow transplantation: value of gray-scale and Doppler US in 100 patients.
    Radiology, 1997, Volume: 204, Issue:2

    Topics: Adult; Busulfan; Child; Diagnosis, Differential; Female; Graft vs Host Disease; Hematopoietic Stem C

1997
Hepatic veno-occlusive disease after myeloablative treatment and bone marrow transplantation: value of gray-scale and Doppler US in 100 patients.
    Radiology, 1997, Volume: 204, Issue:2

    Topics: Adult; Busulfan; Child; Diagnosis, Differential; Female; Graft vs Host Disease; Hematopoietic Stem C

1997
[Severe hepatic veno-occlusive disease (VOD) which was successfully treated with supportive therapy, but subsequently developed late-recurrence].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:2

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Chronic Disease; Cyclophosphamide; Cyclosporine; Graft

1998
Busulfan, cyclophosphamide and total body irradiation as conditioning for allogeneic bone marrow transplantation for acute and chronic myeloid leukemia.
    Bone marrow transplantation, 1998, Volume: 21, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1998
Big BU/CY is associated with a favorable long-term outcome in patients allotransplanted for chronic myelogenous leukemia in chronic phase.
    Bone marrow transplantation, 1998, Volume: 21, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclop

1998
Allogeneic bone marrow transplantation for childhood leukemia following a busulfan and melphalan preparative regimen.
    Bone marrow transplantation, 1998, Volume: 22, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; C

1998
High-dose busulfan and cyclophosphamide are an effective conditioning regimen for allogeneic bone marrow transplantation in chemosensitive multiple myeloma.
    Bone marrow transplantation, 1998, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combin

1998
Primary Sjögren's syndrome followed by chronic myelogenous leukemia: a case report with a ten year history.
    The Journal of dermatology, 1998, Volume: 25, Issue:7

    Topics: Adult; Antibodies, Antinuclear; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Fatal Outco

1998
High incidence of extramedullary relapse of AML after busulfan/cyclophosphamide conditioning and allogeneic stem cell transplantation.
    Bone marrow transplantation, 1998, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Graft vs Host Disease;

1998
Allogeneic BMT for haematological disorders: single centre experience of University Hospital Bratislava.
    Bone marrow transplantation, 1998, Volume: 22 Suppl 4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1998
Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation.
    Bone marrow transplantation, 1999, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Chronic Disease; Cycloph

1999
Impact of previous high-dose therapy on outcome after allografting for multiple myeloma.
    Bone marrow transplantation, 1999, Volume: 23, Issue:7

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Female; G

1999
The role of thiotepa in allogeneic bone marrow transplantation for genetic diseases.
    Bone marrow transplantation, 1999, Volume: 23, Issue:9

    Topics: Adolescent; Alkylating Agents; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclo

1999
Primary renal aspergillosis: extremely uncommon presentation in patients treated with bone marrow transplantation.
    Bone marrow transplantation, 1999, Volume: 24, Issue:1

    Topics: Aspergillosis; Aspergillus; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; F

1999
The role of thiotepa in allogeneic stem cell transplantation in patients with leukemia.
    Leukemia research, 1999, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Combined Mo

1999
Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:3

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents; Antilymphocyte Serum; Bone Marrow Transplantati

1999
Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma.
    Bone marrow transplantation, 2000, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2000
Graft vs autoimmunity following allogeneic non-myeloablative blood stem cell transplantation in a patient with chronic myelogenous leukemia and severe systemic psoriasis and psoriatic polyarthritis.
    Experimental hematology, 2000, Volume: 28, Issue:7

    Topics: Adult; Antineoplastic Agents; Arthritis, Psoriatic; Autoimmunity; Busulfan; Graft vs Host Disease; G

2000
Dose-reduced conditioning for allogeneic blood stem cell transplantation: durable engraftment without antithymocyte globulin.
    Bone marrow transplantation, 2000, Volume: 26, Issue:2

    Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Disease-Free Survival; Female; G

2000
Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia.
    Bone marrow transplantation, 2000, Volume: 26, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Prescho

2000
Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia.
    Bone marrow transplantation, 2000, Volume: 26, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; B

2000
The influence of early transplantation, age, GVHD prevention regimen, and other factors on outcome of allogeneic transplantation for CML following BuCy.
    Bone marrow transplantation, 2000, Volume: 26, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow Transplantation; Busulfan; Cause of Death; Cycloph

2000
Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies.
    Leukemia, 2000, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool

2000
Results of an outpatient-based stem cell allotransplant program using nonmyeloablative conditioning regimens.
    American journal of hematology, 2001, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Ambulatory Care; Busulfan; Child; Cyclophosphamide; Cyclosporine; Female; Follow-

2001
Successful application of nonmyeloablative transplantation for paroxysmal nocturnal hemoglobinuria.
    Experimental hematology, 2001, Volume: 29, Issue:5

    Topics: Antilymphocyte Serum; Busulfan; Cladribine; Cyclosporine; Graft Survival; Graft vs Host Disease; Hem

2001
Allogeneic bone marrow transplantation for chronic myeloid leukemia: a retrospective study of busulfan-cytoxan versus total body irradiation-cytoxan as preparative regimen in Koreans.
    Clinical transplantation, 2001, Volume: 15, Issue:3

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Drug Administration Schedule; Female

2001
A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antilymphocyte Serum; Bone Marrow; Busulfan; Cell

2001
Dose-reduced conditioning for allografting in 44 patients with chronic myeloid leukaemia: a retrospective analysis.
    British journal of haematology, 2001, Volume: 115, Issue:1

    Topics: Adult; Aged; Antigens, CD34; Busulfan; Cytarabine; Disease-Free Survival; Drug Administration Schedu

2001
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
    Haematologica, 2002, Volume: 87, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine;

2002
Mixed chimaerism is common at the time of acute graft-versus-host disease and disease response in patients receiving non-myeloablative conditioning and allogeneic stem cell transplantation.
    British journal of haematology, 2001, Volume: 115, Issue:4

    Topics: Adult; Aged; Bone Marrow Cells; Busulfan; Cell Count; Cyclophosphamide; Female; Graft vs Host Diseas

2001
[The toxicity of busulphan and cyclophosphamide as the preparative regimen for allogeneic peripheral blood stem cell transplantation].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2000, Volume: 21, Issue:8

    Topics: Acute Disease; Adult; Busulfan; Cyclophosphamide; Cystitis; Disease-Free Survival; Esophagitis; Fema

2000
Treatment of myelodysplastic syndrome with busulfan-cyclophosphamide conditioning followed by allogeneic BMT.
    Bone marrow transplantation, 1992, Volume: 10, Issue:5

    Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Trans

1992
Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience.
    Bone marrow transplantation, 1992, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1992
Second transplants for patients with chronic myeloid leukaemia in relapse after original transplant with T-depleted donor marrow: feasibility of using busulphan alone for re-conditioning.
    British journal of haematology, 1992, Volume: 80, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Cells; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Fe

1992
Allogeneic bone marrow transplantation in high-risk myeloid disorders using busulfan, cytosine arabinoside and cyclophosphamide (BAC).
    Bone marrow transplantation, 1992, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1992
Marrow transplantation for paroxysmal nocturnal hemoglobinuria.
    American journal of hematology, 1992, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cy

1992
Marrow transplantation in patients with acute myeloid leukemia.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Drug Administration Schedule

1992
Induction of cutaneous graft-versus-host disease by administration of cyclosporine to patients undergoing autologous bone marrow transplantation for acute myeloid leukemia.
    Blood, 1992, Jun-01, Volume: 79, Issue:11

    Topics: Adolescent; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyc

1992
Treatment of infant leukemia with busulfan, cyclophosphamide +/- etoposide and bone marrow transplantation.
    Bone marrow transplantation, 1992, Volume: 9, Issue:5

    Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Combined Modality Therapy; Cyclophosphamide

1992
Radiation-free preparation for allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow T

1992
Improved results of allogeneic bone marrow transplantation for advanced hematologic malignancy using busulfan, cyclophosphamide and etoposide as cytoreductive and immunosuppressive therapy.
    Bone marrow transplantation, 1991, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Cyclopho

1991
Influence of immunosuppression on acute liver toxicity after intensified conditioning regimens for bone marrow transplantation in children.
    Blood, 1991, Apr-01, Volume: 77, Issue:7

    Topics: Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Drug Therapy, Combination; Etoposide; Gr

1991
Bone marrow transplantation in thalassemia.
    Hematology/oncology clinics of North America, 1991, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1991
Bone marrow transplantation from unrelated donors for genetic diseases following conditioning with Busulphan and Cyclophosphamide.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 2

    Topics: Actuarial Analysis; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide

1991
Bone marrow transplantation in sickle cell anaemia.
    Archives of disease in childhood, 1991, Volume: 66, Issue:10

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Bone Marrow Transplantation; Busulfan; Child; Child, Prescho

1991
Busulphan/cyclophosphamide conditioning for bone marrow transplantation may lead to failure of hair regrowth.
    Bone marrow transplantation, 1991, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Alopecia; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; F

1991
Regimen-related toxicity of a busulfan-cyclophosphamide conditioning regimen in 70 patients undergoing allogeneic bone marrow transplantation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:7

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Bone Marrow Transplantation; Busulfan; Cyclophosphami

1991
Busulfan disposition in children.
    Blood, 1990, Apr-15, Volume: 75, Issue:8

    Topics: Administration, Oral; Bone Marrow Transplantation; Busulfan; Child, Preschool; Dose-Response Relatio

1990
Bone marrow transplantation following busulfan and cyclophosphamide for acute myelogenous leukemia.
    Bone marrow transplantation, 1990, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1990
CMV infections in thalassemia patients after BMT.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Adolescent; Blood Transfusion; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclo

1989
The role of busulfan/cyclophosphamide regimens in allogeneic and autologous bone marrow transplantation.
    Cancer investigation, 1989, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cycl

1989
New conditioning regimens for high risk marrow transplants.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1989
Myeloablative conditioning for marrow transplantation in myelodysplastic syndromes and paroxysmal nocturnal haemoglobinuria.
    Bone marrow transplantation, 1989, Volume: 4, Issue:1

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Bone Marrow Transplantation; Busulfan

1989
Requirements for the induction and adoptive transfer of cyclosporine-induced syngeneic graft-versus-host disease.
    The Journal of experimental medicine, 1989, Mar-01, Volume: 169, Issue:3

    Topics: Animals; Autoimmune Diseases; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporins;

1989
Replacing total body irradiation with busulfan as conditioning of patients with leukemia for allogeneic marrow transplantation.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 3

    Topics: Actuarial Analysis; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Graft vs Host D

1989
Allogeneic bone marrow transplantation after high-dose busulfan and cyclophosphamide in patients with acute nonlymphocytic leukemia.
    Blood, 1989, Volume: 73, Issue:8

    Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Drug Administration Schedule

1989
Bone marrow transplantation in thalassemia. The experience of Pesaro.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Graft

1989
Bone marrow transplantation for thalassaemia--a preliminary report from the International Bone Marrow Transplant Registry.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Actuarial Analysis; Adolescent; Bone Marrow Transplantation; Busulfan; Child; Female; Graft vs Host

1989
Bone marrow transplantation for thalassemia in Pescara.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Cyclophosphamide; Female; Graft vs Host Di

1989
Bone marrow transplantation for thalassaemia: Westminster Children's Hospital and United Kingdom experience.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; England; Graft vs

1989
Bone marrow transplantation (BMT) for thalassemia major (TM). The French experience.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; France; Graft Reje

1989
Patterns of graft rejection after bone marrow transplant in thalassemia.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Graft

1989
Liver iron stores before and after bone marrow transplantation for thalassemia.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Bone Marrow Transplantation; Busulfan; Child; Cyclophosphamide; Deferoxamine; Ferritins; Graft vs Ho

1989
Escalating doses of etoposide with cyclophosphamide and fractionated total body irradiation or busulfan as conditioning for bone marrow transplantation.
    Bone marrow transplantation, 1989, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1989
Busulfan, cyclophosphamide and fractionated total body irradiation as a preparatory regimen for marrow transplantation in patients with advanced hematological malignancies: a phase I study.
    Bone marrow transplantation, 1989, Volume: 4, Issue:6

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Dose-Response Relationship, Drug; Dr

1989
Immunologic recovery in thalassemic marrow graft recipients following high-dose busulfan and cyclophosphamide.
    Transplantation, 1988, Volume: 46, Issue:3

    Topics: Antigens, Differentiation, T-Lymphocyte; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cy

1988
Marrow transplantation for thalassaemia following busulphan and cyclophosphamide.
    Lancet (London, England), 1985, Jun-15, Volume: 1, Issue:8442

    Topics: Actuarial Analysis; Age Factors; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Com

1985
[Bone marrow transplantation in chronic myeloid leukemia. Influence of gnotobiotic measures, especially antiviral prophylaxis].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-14, Volume: 111, Issue:7

    Topics: Acyclovir; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclos

1986
Diminishing morbidity and mortality of bone marrow transplantation.
    Vox sanguinis, 1986, Volume: 51 Suppl 2

    Topics: Administration, Oral; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophospha

1986
Successful marrow transplantation for acute myelocytic leukemia following therapy for Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:10

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamid

1988
Syngeneic graft-versus-host disease: failure of autoregulation in self/non-self discrimination.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Animals; Autoimmune Diseases; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Graft vs Host

1988
Bone marrow transplantation in beta-thalassemia major with prevention of graft-vs-host disease.
    Birth defects original article series, 1988, Volume: 23, Issue:5B

    Topics: Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Humans; Infa

1988
Bone-marrow transplantation for thalassaemia.
    The Medical journal of Australia, 1986, Mar-31, Volume: 144, Issue:7

    Topics: Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Graft vs Host Disease; Humans; Infant; Info

1986
Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment.
    Blood, 1985, Volume: 66, Issue:6

    Topics: Adult; Antilymphocyte Serum; Base Sequence; Blood Grouping and Crossmatching; Bone Marrow Transplant

1985
Use of donors sharing one genetic haplotype for bone marrow transplantation.
    The Tokai journal of experimental and clinical medicine, 1985, Volume: 10, Issue:2-3

    Topics: Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporins; Dose-Response Relationship, I

1985
Runt diseases as a model of immunosuppressive therapy.
    Folia biologica, 1966, Volume: 12, Issue:4

    Topics: Aminopterin; Animals; Busulfan; Cyclophosphamide; Dactinomycin; Graft vs Host Disease; Immunosuppres

1966
[The influence of age and experimentally-induced disease on the tolerance of cytostatically-active materials in mice].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:2

    Topics: Age Factors; Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide;

1967