Page last updated: 2024-10-24

busulfan and Disease Models, Animal

busulfan has been researched along with Disease Models, Animal in 97 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs."8.12Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022)
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)."7.81[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015)
" We treated transgenic mice that over-express human mutant superoxide dismutase 1, a model of amyotrophic lateral sclerosis, with busulfan to determine whether this commonly used chemotherapeutic leads to stable chimerism and promotes the entry of bone marrow-derived cells into spinal cord."7.79Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. ( Barr, C; Humphries, RK; Krieger, C; Lewis, CA; Manning, J; Peake, K; Rossi, F, 2013)
"Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes."5.51Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019)
"Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available."5.43A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan. ( Abe, T; Hanazono, Y; Hishikawa, S; Kono, S; Kunita, S; Ohnuki, T, 2016)
" In conclusion, although TH produced only a moderate effect against BCL1 leukemia when used alone, its combination with CY is promising and should be tested further in allogeneic murine models and clinical studies."5.34The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation. ( Abdul-Hai, A; Ergas, D; Resnick, IB; Shapira, MY; Slavin, S; Weiss, L, 2007)
"In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs."4.12Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022)
" We describe a protocol that involves pre-conditioning of Casper, a pigmentation mutant of zebrafish with busulfan that led to a higher rate of engraftment of hepatocellular carcinoma and acute myeloid leukemia cells."3.91An efficient method to generate xenograft tumor models of acute myeloid leukemia and hepatocellular carcinoma in adult zebrafish. ( Jayandharan, GR; Khan, N; Mahajan, NK; Sinha, P, 2019)
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)."3.81[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015)
"Busulfan is a chemotherapeutic drug that induces sterility, azoospermia and testicular atrophy."3.80Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol. ( Akhondi, MM; Jafarian, A; Lakpour, N; Pejhan, N; Sadeghi, MR; Salehkhou, S, 2014)
" We treated transgenic mice that over-express human mutant superoxide dismutase 1, a model of amyotrophic lateral sclerosis, with busulfan to determine whether this commonly used chemotherapeutic leads to stable chimerism and promotes the entry of bone marrow-derived cells into spinal cord."3.79Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. ( Barr, C; Humphries, RK; Krieger, C; Lewis, CA; Manning, J; Peake, K; Rossi, F, 2013)
"After establishing the feasibility of fiberoptic confocal fluorescent microscopy to identify antibody labeled sperm in vivo C57/B6 mice underwent intraperitoneal injection of busulfan to induce azoospermia."3.78Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval. ( Costabile, RA; Herr, JC; Kavoussi, PK; Lowe, GJ; Lysiak, JJ; Shetty, J; Smith, RP; Steers, WD, 2012)
"To evaluate the potential of diffusion-weighted imaging (DWI) for monitoring dose-dependent tumor response in a mouse-xenograft model of Ewing sarcoma after administration of treosulfan in different dosages."3.75Diffusion-weighted imaging as predictor of therapy response in an animal model of Ewing sarcoma. ( Elverfeldt, DV; Juettner, E; Kontny, U; Reichardt, W; Uhl, M, 2009)
"Development of experimental the syndrome of disseminated intravascular coagulation, DIC syndrome, in organism laboratory animals from affect preparation "EFA-2" by accompanied increase quantity of neutrophiles circulations, modifications of the lysosomal apparatus of neutrophiles the activity of the serum acid phosphatase increased, characteristic damage on hemostasis system and typical alteration in some organs."3.70[The effect of the lysosomal function of circulating neutrophils on hemostasis and on the morphological changes in the internal organs in the disseminated intravascular coagulation syndrome]. ( Boiarchuk, OD; Koval', SB; Lunina, NV, 1999)
" Rats treated with busulfan to induce thrombocytopenia exhibited a 90% decrease in circulating platelets."3.69Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion. ( Lentsch, AB; Lindberg, RA; Miller, FN; Slaaf, DW, 1994)
" In this study, cyclophosphamide combined with busulfan was used to establish an animal model."1.62Experimental study for the establishment of a chemotherapy-induced ovarian insufficiency model in rats by using cyclophosphamide combined with busulfan. ( Feng, X; Ling, L; Luo, Y; Tang, D; Wang, Y; Xiong, Z; Zhang, W, 2021)
"Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes."1.51Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019)
"Aplastic anemia was generated in mice with the administration of busulfan and cyclophosphamide followed by the characterization of the disease with peripheral blood hemogram, histopathological and cytochemical examinations of bone marrow."1.51Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population. ( Chatterjee, R; Law, S, 2019)
" Conditioning with treosulfan alone at nonmyeloablative dosing (3."1.48Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease. ( Devadasan, D; Goldman, FD; Pawlik, KM; Sun, CW; Townes, TM; Westin, ER; Wu, LC, 2018)
"Animal disease models have been criticized for lack of resemblance to human illnesses, hampering transfer of knowledge from preclinical research to clinical medicine."1.43A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation. ( Elezkurtaj, S; Kalupa, M; Penack, O; Riesner, K; Shi, Y, 2016)
"Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available."1.43A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan. ( Abe, T; Hanazono, Y; Hishikawa, S; Kono, S; Kunita, S; Ohnuki, T, 2016)
"Non-obstructive azoospermia is the most challenging type of male infertility."1.40Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model. ( He, D; Li, X; Lin, T; Liu, X; Peng, J; Wei, G; Zhang, D; Zhang, Y; Zhu, J, 2014)
"Oral mucositis is one of the most debilitating side effects in patient undergoing chemotherapy or chemoradiotherapy."1.40Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis. ( Biswas, S; Nandakumar, K; Patel, A; Ramalingayya, GV; Shoja, MH, 2014)
"Busulfan was used to induce testicular failure in 3-week-old immature FVB/NJNarl wild-type recipient mice."1.38Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice. ( Chen, CH; Hsu, MI; Huang, YH; Lai, WF; Tzeng, CR; Wang, CW, 2012)
"To establish a novel severe aplastic anemia (SAA) mouse model by interferon-γ (IFN-γ) plus busulphan."1.37[A novel severe aplastic anemia mouse model induced by IFN-γ plus busulphan]. ( Chen, XF; Lin, ZH; Liu, H; Liu, HY; Ning, FY; Sun, F; Wang, H, 2011)
"Busulfan treatment did not affect edema and hemorrhage in P-selectin- or PSGL-1-deficient mice, suggesting that the effect by busulfan is dependent on P-selectin and PSGL-1 expression."1.36Platelets control leukocyte recruitment in a murine model of cutaneous arthus reaction. ( Fujimoto, M; Hara, T; Hasegawa, M; Iwata, Y; Komura, K; Muroi, E; Ogawa, F; Sato, S; Shimizu, K; Takenaka, M; Yanaba, K, 2010)
"Infantile malignant osteopetrosis is a fatal disease caused by lack of functional osteoclasts."1.35Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis. ( Askmyr, M; Ehinger, M; Flores, C; Hjalt, T; Holmberg, J; Richter, J, 2009)
"In busulfan-treated embryos, diffuse cell death was evident in both ectoderm and mesoderm, peaking at E13."1.34Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: a common mechanism of disruption leads to divergent phenotypes. ( Naruse, T; Oberg, KC; Ogino, T; Takagi, M; Takahara, M, 2007)
" In conclusion, although TH produced only a moderate effect against BCL1 leukemia when used alone, its combination with CY is promising and should be tested further in allogeneic murine models and clinical studies."1.34The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation. ( Abdul-Hai, A; Ergas, D; Resnick, IB; Shapira, MY; Slavin, S; Weiss, L, 2007)
"The incidence of oral mucositis in model group was as high as 80."1.34[Establishment of an animal model of oral mucositis induced by conditioning regimen of haematopoietic stem cell transplantation]. ( Chen, XB; Tong, XZ; Wang, X, 2007)
"To develop an aplastic anemia model with hematopoietic stem cell failure in rats."1.31[A novel rat aplastic anemia model induced by 5-fluorouracil combined with busulfan]. ( Chu, J; Ding, S; Liu, A; Wang, S; Xu, S; Zhao, J, 2001)
"BUF rats suffering from severe relapsing experimental autoimmune encephalomyelitis (R-EAE), a model for multiple sclerosis, were treated with intensive cytoreductive therapy and grafting of allogeneic bone marrow (BM)."1.29Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation. ( Mulder, AH; van Bekkum, DW; van Gelder, M, 1996)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199013 (13.40)18.7374
1990's6 (6.19)18.2507
2000's18 (18.56)29.6817
2010's45 (46.39)24.3611
2020's15 (15.46)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Ganjibakhsh, M1
Mehraein, F1
Koruji, M1
Bashiri, Z1
Jiang, S1
Xu, Y1
Fan, Y1
Hu, Y1
Zhang, Q2
Su, W1
Mobarak, H1
Rahbarghazi, R1
Nouri, M1
Heidarpour, M1
Mahdipour, M1
Hao, Y1
Fang, H1
Yan, X1
Shen, W2
Liu, J1
Han, P1
Zhao, Y2
Zhang, W2
Feng, Y1
Ziaeipour, S1
Rezaei, F1
Piryaei, A1
Abdi, S1
Moradi, A1
Ghasemi, A1
Azad, N1
Abdollahifar, MA2
Lei, B1
Xie, L1
Zhang, S1
Lv, D1
Shu, F1
Deng, Y1
Luo, Q1
Liu, R1
Wang, L1
Hou, Y1
Zhang, H1
Xie, Y1
Chen, H2
Luo, D1
Yang, X1
Yao, J1
Zhang, C1
Lv, L1
Guo, Z1
Deng, C3
Li, Y2
Liang, X1
Sun, X1
Liu, G1
Qu, N1
Kuramasu, M1
Nagahori, K1
Ogawa, Y1
Hayashi, S1
Hirayanagi, Y1
Terayama, H1
Suyama, K1
Sakabe, K1
Itoh, M1
Jia, W1
Zhen, M1
Li, L2
Zhou, C1
Sun, Z2
Liu, S2
Zhao, Z1
Li, J3
Wang, C1
Bai, C1
Yu, S1
Zhang, FL1
Li, YQ1
Sun, ZY1
Ebrahimi, V1
Aliaghaei, A1
Raoofi, A1
Khosravi, A1
Hasani, A1
Mehdizadeh, A1
Asadi, M1
Chen, C2
Li, S1
Hu, C1
Cao, W1
Fu, Q1
Zheng, L1
Huang, J1
Chen, Z1
Liu, M1
Hu, JH1
Gao, Y1
Jiang, MH1
Tang, D1
Feng, X1
Ling, L1
Luo, Y1
Wang, Y1
Xiong, Z1
Burdette, AJ1
Andrew Pratt, G1
Campagna, MV1
Sheppard, FR1
Chatterjee, R2
Law, S2
Llewellyn, GN1
Alvarez-Carbonell, D1
Chateau, M1
Karn, J1
Cannon, PM1
Dighe, NM1
Tan, KW1
Tan, LG1
Shaw, SSW1
Buckley, SMK1
Sandikin, D1
Johana, N1
Tan, YW1
Biswas, A1
Choolani, M1
Waddington, SN1
Antoniou, MN1
Chan, JKY1
Mattar, CNZ1
Devadasan, D1
Sun, CW1
Westin, ER1
Wu, LC1
Pawlik, KM1
Townes, TM1
Goldman, FD1
Huang, Y3
Zhao, L1
Yao, C1
Yang, C1
Zhu, Z1
Li, P1
Tian, R1
He, Z1
Li, Z1
Chen, QH1
Wang, J2
Lin, SF1
Xue, HM1
Kadam, P1
Ntemou, E1
Baert, Y2
Van Laere, S1
Van Saen, D2
Goossens, E2
Manshadi, MD1
Navid, S1
Hoshino, Y1
Daneshi, E1
Noory, P1
Abbasi, M1
Khan, N1
Mahajan, NK1
Sinha, P1
Jayandharan, GR1
Liu, Y2
Wu, X2
Jiang, H1
Guo, X1
Yin, X1
Zhu, W1
Pan, Y1
Wang, H2
Liang, Y2
Zhu, X1
Cai, YT1
Xiong, CL1
Shen, SL1
Rao, JP1
Liu, TS1
Qiu, F1
Skaznik-Wikiel, ME1
McGuire, MM1
Sukhwani, M1
Donohue, J1
Chu, T1
Krivak, TC1
Rajkovic, A1
Orwig, KE1
Lewis, CA1
Manning, J1
Barr, C1
Peake, K1
Humphries, RK1
Rossi, F1
Krieger, C1
Li, JP1
Guo, WB1
He, JC1
Yu, QF1
Wu, XQ1
Mao, XM1
Zhang, FB1
Jy, W1
Johansen, ME1
Bidot, C1
Horstman, LL1
Ahn, YS1
Gutti, TL1
Knibbe, JS1
Makarov, E1
Zhang, J1
Yannam, GR1
Gorantla, S2
Sun, Y1
Mercer, DF1
Suemizu, H1
Wisecarver, JL1
Osna, NA1
Bronich, TK1
Poluektova, LY1
Jafarian, A1
Sadeghi, MR1
Pejhan, N1
Salehkhou, S1
Lakpour, N1
Akhondi, MM1
Zhang, D1
Liu, X1
Peng, J1
He, D1
Lin, T1
Zhu, J1
Li, X2
Zhang, Y2
Wei, G1
Kanaji, S1
Fahs, SA1
Ware, J1
Montgomery, RR1
Shi, Q1
Patel, A1
Biswas, S1
Shoja, MH1
Ramalingayya, GV1
Nandakumar, K1
Chen, YF1
Zhao, ZQ1
Wu, ZM1
Zou, ZY1
Luo, XJ1
Xie, C1
Li, N1
Hu, W1
Yang, W1
Chen, P1
Chen, Y1
Lai, D1
Wang, F1
Yao, X1
Xiang, C1
Riesner, K1
Kalupa, M1
Shi, Y1
Elezkurtaj, S1
Penack, O1
Qiao, J1
Xia, Y1
Chu, P1
Yao, H1
Xu, L1
Qi, K1
Xu, K1
Zeng, L1
He, X1
Xu, X1
Yi, W1
Ye, Y1
Guo, K1
Rathe, M1
Thomassen, M1
Shen, RL1
Pontoppidan, PE1
Husby, S1
Müller, K1
Kruse, TA1
Sangild, PT1
Abe, T1
Kono, S1
Ohnuki, T1
Hishikawa, S1
Kunita, S1
Hanazono, Y1
Zhang, T1
Yan, D1
Yang, Y1
Ma, A1
Wang, Z1
Pan, Q1
Hu, P1
Nikolaishvili-Feinberg, N1
Scesa, G1
Bi, Y1
Pan, D1
Moore, D1
Bongarzone, ER1
Sands, MS1
Miller, R1
Kafri, T1
Wu, C1
Shen, Q1
Zhou, Z1
Liu, W1
Hua, J1
Horn, MM1
Paz, AH1
Duarte, ME1
Baldo, G1
Belardinelli, MC1
Matte, U1
Lima, EO1
Passos, EP1
Sadeghi, B3
Aghdami, N1
Hassan, Z3
Forouzanfar, M1
Rozell, B3
Abedi-Valugerdi, M2
Hassan, M3
Enquist, IB1
Nilsson, E1
Månsson, JE1
Ehinger, M2
Richter, J2
Karlsson, S1
Askmyr, M1
Holmberg, J1
Flores, C1
Hjalt, T1
Peranteau, WH1
Heaton, TE1
Gu, YC1
Volk, SW1
Bauer, TR1
Alcorn, K1
Tuschong, LM1
Johnson, MP1
Hickstein, DD1
Flake, AW1
Reichardt, W1
Juettner, E1
Uhl, M1
Elverfeldt, DV1
Kontny, U1
Zimecki, M1
Artym, J1
Kocieba, M1
Weber-Dabrowska, B1
Borysowski, J1
Górski, A1
Hara, T1
Shimizu, K1
Ogawa, F1
Yanaba, K1
Iwata, Y1
Muroi, E1
Takenaka, M1
Komura, K1
Hasegawa, M1
Fujimoto, M1
Sato, S1
Kornerup, KN1
Salmon, GP1
Pitchford, SC1
Liu, WL1
Page, CP1
Duchartre, Y1
Petit, N1
Moya, C1
Lalanne, M1
Dubus, P1
Verneuil, Hd1
Moreau-Gaudry, F1
Richard, E1
Al-Hashmi, S2
Concha, H1
Lundmark, C1
Grönvik, KO1
Ning, FY1
Lin, ZH1
Liu, H1
Chen, XF1
Sun, F1
Liu, HY1
Ning, L1
in't Veld, P1
Tournaye, H1
Chen, CH1
Wang, CW1
Hsu, MI1
Huang, YH1
Lai, WF1
Tzeng, CR1
Smith, RP1
Lowe, GJ1
Kavoussi, PK1
Steers, WD1
Costabile, RA1
Herr, JC1
Shetty, J1
Lysiak, JJ1
Kean, LS1
Manci, EA1
Perry, J1
Balkan, C1
Coley, S1
Holtzclaw, D1
Adams, AB1
Larsen, CP1
Hsu, LL1
Archer, DR1
Suemitsu, R1
Yoshino, I1
Shoji, F1
Yamaguchi, M1
Tomita, Y1
Maehara, Y1
Chen, J1
Zarbock, A1
Singbartl, K1
Ley, K1
Sneller, H1
Walters, L1
Sharp, JG1
Pirruccello, SJ1
West, JT1
Wood, C1
Dewhurst, S1
Gendelman, HE1
Poluektova, L1
Huang, XB1
Li, HG1
Naruse, T1
Takahara, M1
Takagi, M1
Oberg, KC1
Ogino, T1
Abdul-Hai, A1
Weiss, L1
Ergas, D1
Resnick, IB1
Slavin, S1
Shapira, MY1
Chen, XB1
Wang, X1
Tong, XZ1
Molyneux, G1
Gibson, FM1
Whayman, M1
Turton, JA1
Hubbard, LL1
Ballinger, MN1
Wilke, CA1
Moore, BB1
Haak, HL2
den Ottolander, GJ1
te Velde, J1
Veenhof, W1
Kleiverda, K1
Spaander, PJ1
Yamagishi, M1
Niki, T1
Hiraoka, A1
Dohmae, N1
Uchino, H1
Lindberg, RA1
Slaaf, DW1
Lentsch, AB1
Miller, FN1
Glass, B1
Uharek, L1
Gaska, T1
Gassmann, W1
Löffler, H1
Müller-Ruchholtz, W1
van Gelder, M1
Mulder, AH1
van Bekkum, DW1
Haddad, S1
Carvalho, TL1
Anselmo-Franci, JA1
Petenusci, SO1
Favaretto, AL1
Koval', SB1
Boiarchuk, OD1
Lunina, NV1
Zhao, J1
Chu, J1
Ding, S1
Xu, S1
Liu, A1
Wang, S1
Greenberger, JS1
Bocaccino, CA1
Szot, SJ1
Moloney, WC1
Pugsley, CA1
Forbes, IJ1
Morley, AA2
Trainor, KJ1
Seshadri, RS1
Morley, A3
Trainor, K1
Remes, J1
Epstein, RB1
Min, KW1
Anderson, SL1
Syzek, L1
Wagner, JE1
Johnson, RJ1
Santos, GW2
Kim, BK1
Shin, HS1
Shulman, HM1
Luk, K1
Deeg, HJ1
Shuman, WB1
Storb, R1
Butler, T1
Rahman, H1
Al-Mahmud, KA1
Islam, M1
Bardhan, P1
Kabir, I1
Rahman, MM1
Blake, J2
Tutschka, PJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Filgrastim for Treatment of Premature Ovarian Insufficiency: Randomized Clinical Trial[NCT02783937]Phase 410 participants (Actual)Interventional2016-11-30Completed
Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965]350 participants (Anticipated)Observational2018-08-15Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for busulfan and Disease Models, Animal

ArticleYear
Animal models for acquired bone marrow failure syndromes.
    Clinical medicine & research, 2005, Volume: 3, Issue:2

    Topics: Anemia, Aplastic; Animals; Benzene; Bone Marrow Diseases; Busulfan; Chloramphenicol; Disease Models,

2005
Experimental drug-induced aplastic anaemia.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Anemia, Aplastic; Animals; Benzene; Busulfan; Chloramphenicol; Colony-Forming Units Assay; Disease M

1980

Other Studies

95 other studies available for busulfan and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
The therapeutic potential of adipose tissue-derived mesenchymal stromal cells in the treatment of busulfan-induced azoospermic mice.
    Journal of assisted reproduction and genetics, 2022, Volume: 39, Issue:1

    Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Immunosuppressive Agents; Male; Mesenchymal

2022
Busulfan impairs blood-testis barrier and spermatogenesis by increasing noncollagenous 1 domain peptide via matrix metalloproteinase 9.
    Andrology, 2022, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Autoantigens; Blood-Testis Barrier; Busulfan; Cell Membr

2022
Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model.
    BMC pharmacology & toxicology, 2022, 07-14, Volume: 23, Issue:1

    Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Humans; Injections; Injections, Intraperiton

2022
Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model.
    International journal of molecular sciences, 2023, Feb-04, Volume: 24, Issue:4

    Topics: Alginates; Animals; Anti-Inflammatory Agents; Busulfan; Disease Models, Animal; Liver; Mice; Oligosa

2023
Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction.
    Andrologia, 2019, Volume: 51, Issue:11

    Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Fever; Male; Mice; Organ Size; Sperm Count;

2019
UBE2W down-regulation promotes cell apoptosis and correlates with hypospermatogenesis.
    Andrologia, 2020, Volume: 52, Issue:1

    Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Dimethyl Sulfoxide; Disease Models, Animal; Do

2020
The Effects of Inhibin B in the Chemotherapy Drug-Induced Premature Ovarian Insufficiency Mice and hPMSCs Treatment.
    Reproductive sciences (Thousand Oaks, Calif.), 2020, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Busulfan; Cyclophosphamide; Disease Models, Animal; Femal

2020
Inhibiting Necroptosis of Spermatogonial Stem Cell as a Novel Strategy for Male Fertility Preservation.
    Stem cells and development, 2020, 04-15, Volume: 29, Issue:8

    Topics: Animals; Busulfan; Cryopreservation; Disease Models, Animal; Fertility Preservation; Male; Mice; Mic

2020
Co-Administration of the Traditional Medicines Hachimi-Jio-Gan and Hochu-Ekki-To Can Reverse Busulfan-Induced Aspermatogenesis.
    International journal of molecular sciences, 2020, Mar-03, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Body Weight; Busulfan; Cell Proliferation; Di

2020
Gadofullerene nanoparticles for robust treatment of aplastic anemia induced by chemotherapy drugs.
    Theranostics, 2020, Volume: 10, Issue:15

    Topics: Anemia, Aplastic; Animals; Antineoplastic Agents, Alkylating; Bone Marrow Cells; Busulfan; Cell Diff

2020
Chestnut polysaccharides benefit spermatogenesis through improvement in the expression of important genes.
    Aging, 2020, 06-21, Volume: 12, Issue:12

    Topics: Animals; Busulfan; Disease Models, Animal; Drugs, Chinese Herbal; Fagaceae; Gene Expression Regulati

2020
Protective effect of curcumin on busulfan-induced renal toxicity in male rats.
    Renal failure, 2020, Volume: 42, Issue:1

    Topics: Animals; Antioxidants; Busulfan; Curcumin; Disease Models, Animal; Injections, Intravenous; Kidney D

2020
Protective Effects of Puerarin on Premature Ovarian Failure via Regulation of Wnt/β-catenin Signaling Pathway and Oxidative Stress.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:4

    Topics: Animals; Apoptosis; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Isoflavones; Mice; O

2021
Substance P restores spermatogenesis in busulfan-treated mice: A new strategy for male infertility therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133

    Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Ex

2021
Experimental study for the establishment of a chemotherapy-induced ovarian insufficiency model in rats by using cyclophosphamide combined with busulfan.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 122

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; Cyclophosphamide; Disea

2021
Evaluation of a new generation platelet-derived hemostatic agent in a rabbit thrombocytopenic model.
    Thrombosis research, 2017, Volume: 158

    Topics: Animals; Blood Platelets; Busulfan; Disease Models, Animal; Hemostatics; Humans; Rabbits; Thrombocyt

2017
Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia.
    European journal of cell biology, 2018, Volume: 97, Issue:1

    Topics: Anemia, Aplastic; Animals; Apoptosis; Bone Marrow; Busulfan; Chemokine CXCL12; Cyclophosphamide; Dis

2018
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.
    Journal of neurovirology, 2018, Volume: 24, Issue:2

    Topics: AIDS Dementia Complex; Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Busulfan; Cell Differenti

2018
A comparison of intrauterine hemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassemia in a HbbTh3/+ murine model.
    Experimental hematology, 2018, Volume: 62

    Topics: Animals; beta-Thalassemia; Bone Marrow Transplantation; Busulfan; Cell Survival; Cellular Microenvir

2018
Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:8

    Topics: Anemia, Sickle Cell; Animals; Antibodies; Antineoplastic Agents, Alkylating; Bone Marrow Transplanta

2018
Effect of Kallikrein-related Peptidase KLK1 on Ameliorating Spermatogenesis Regeneration in Busulfan-induced Azoospermic Mice and Promoting Mouse Spermatogonial Stem Cell Proliferation In Vitro.
    Urology, 2018, Volume: 122

    Topics: Animals; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Humans; Injec

2018
[Relationship of Blimp-1 Hypoexpression with Pathogenesis of Aplastic Anemia].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:5

    Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Mice; Positive Regulatory Domain I-Bind

2018
Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice.
    Stem cell research & therapy, 2018, 11-21, Volume: 9, Issue:1

    Topics: Adult Germline Stem Cells; Animals; Busulfan; Cadmium Chloride; Cell Survival; Disease Models, Anima

2018
The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure.
    Microscopy research and technique, 2019, Volume: 82, Issue:6

    Topics: Animals; Anti-Mullerian Hormone; Busulfan; Cell Transplantation; Disease Models, Animal; Female; Fol

2019
An efficient method to generate xenograft tumor models of acute myeloid leukemia and hepatocellular carcinoma in adult zebrafish.
    Blood cells, molecules & diseases, 2019, Volume: 75

    Topics: Animals; Busulfan; Carcinoma, Hepatocellular; Cell Compartmentation; Disease Models, Animal; Heterog

2019
Raman spectroscopic analysis of testicular lamina propria predicts spermatogenesis in a mouse infertility model.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:5

    Topics: Animals; Busulfan; Disease Models, Animal; Infertility, Male; Male; Mice; Mucous Membrane; Seminifer

2019
Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population.
    Pathology, research and practice, 2019, Volume: 215, Issue:4

    Topics: Anemia, Aplastic; Animals; Apoptosis; Busulfan; Cell Proliferation; Cellular Senescence; Disease Mod

2019
The Preconditioning of Busulfan Promotes Efficiency of Human CD133+ Cells Engraftment in NOD Shi-SCID IL2Rγcnull (NOG) Mice via Intra-Bone Marrow Injection.
    Cell transplantation, 2019, Volume: 28, Issue:7

    Topics: AC133 Antigen; Animals; Busulfan; Cell Differentiation; Disease Models, Animal; Female; Flow Cytomet

2019
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
    Andrologia, 2019, Volume: 51, Issue:6

    Topics: Animals; Apoptosis; Blood-Testis Barrier; Busulfan; Cadherins; Cell Adhesion; Culture Media, Conditi

2019
Granulocyte colony-stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy.
    Fertility and sterility, 2013, Volume: 99, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disease Models,

2013
Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Ce

2013
[Establishing a mouse model of Sertoli-cell-only syndrome by administration of busulfan].
    Zhonghua nan ke xue = National journal of andrology, 2013, Volume: 19, Issue:4

    Topics: Animals; Busulfan; Cold Temperature; Disease Models, Animal; Male; Mice; Mice, Inbred Strains; Organ

2013
Red cell-derived microparticles (RMP) as haemostatic agent.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:4

    Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation Disorders; Busulfan; Cell Separatio

2013
Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice.
    The American journal of pathology, 2014, Volume: 184, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; Coinfection; Disease Models, Animal; Hematopoi

2014
Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol.
    Andrologia, 2014, Volume: 46, Issue:10

    Topics: Animals; Azoospermia; Busulfan; Cyclin B1; Disease Models, Animal; Estradiol; Follicle Stimulating H

2014
Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model.
    International journal of molecular sciences, 2014, Jul-24, Volume: 15, Issue:8

    Topics: Animals; Antineoplastic Agents; Azoospermia; Bone Marrow Cells; Busulfan; Cell Transdifferentiation;

2014
Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:10

    Topics: Animals; Bernard-Soulier Syndrome; Bleeding Time; Busulfan; Disease Models, Animal; Gene Transfer Te

2014
Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Animals; Body Weight; Busulfan; Chromatography, High Pressure Liquid; Disease Models, Animal; Feedin

2014
The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:12

    Topics: Anemia, Aplastic; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Busulfan; Cyclophos

2014
[Establishment of a graft-versus-host disease mouse model for haplo-identical bone marrow transplantation with busulfan and fludarabine conditioning regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:3

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Drug Combinations; Graft vs

2015
Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure.
    Journal of translational medicine, 2015, May-12, Volume: 13

    Topics: Adult; Animals; Body Weight; Busulfan; Cell Differentiation; Cyclophosphamide; Disease Models, Anima

2015
A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation.
    Bone marrow transplantation, 2016, Volume: 51, Issue:3

    Topics: Acute Disease; Allografts; Animals; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Graf

2016
Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation.
    Scientific reports, 2015, Dec-04, Volume: 5

    Topics: Adenosine Triphosphate; Animals; Busulfan; Carrier Proteins; Chemical and Drug Induced Liver Injury;

2015
[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:12

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Gr

2015
Chemotherapy Modulates Intestinal Immune Gene Expression Including Surfactant Protein-D and Deleted in Malignant Brain Tumors 1 in Piglets.
    Chemotherapy, 2016, Volume: 61, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Busulfan; Cyclophosphamide; Disease Models, Animal;

2016
A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan.
    Experimental animals, 2016, Nov-01, Volume: 65, Issue:4

    Topics: Acute Disease; Animals; Antineoplastic Agents, Alkylating; Bleeding Time; Busulfan; Disease Models,

2016
The comparison of animal models for premature ovarian failure established by several different source of inducers.
    Regulatory toxicology and pharmacology : RTP, 2016, Volume: 81

    Topics: Animals; Busulfan; Cisplatin; Cyclohexenes; Cyclophosphamide; Disease Models, Animal; Dose-Response

2016
Hematopoietic Stem cell transplantation and lentiviral vector-based gene therapy for Krabbe's disease: Present convictions and future prospects.
    Journal of neuroscience research, 2016, Volume: 94, Issue:11

    Topics: Animals; Antigens, CD; Antimetabolites; Brain; Busulfan; Cell Line, Transformed; Cycloserine; Diseas

2016
Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Adult Germline Stem Cells; Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation;

2016
Germinative testicular cells and bone marrow mononuclear cells transplanted to a rat model of testicular degeneration.
    Cloning and stem cells, 2008, Volume: 10, Issue:4

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Germ Cell

2008
GVHD after chemotherapy conditioning in allogeneic transplanted mice.
    Bone marrow transplantation, 2008, Volume: 42, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan

2008
Successful low-risk hematopoietic cell therapy in a mouse model of type 1 Gaucher disease.
    Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:3

    Topics: Animals; Bone Marrow; Busulfan; Cell- and Tissue-Based Therapy; Disease Models, Animal; Flow Cytomet

2009
Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis.
    Experimental hematology, 2009, Volume: 37, Issue:2

    Topics: Animals; Animals, Newborn; Blindness; Busulfan; Disease Models, Animal; Hematopoiesis; Humans; Infan

2009
Haploidentical in utero hematopoietic cell transplantation improves phenotype and can induce tolerance for postnatal same-donor transplants in the canine leukocyte adhesion deficiency model.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:3

    Topics: Animals; Busulfan; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dogs; Female; Fetal T

2009
Diffusion-weighted imaging as predictor of therapy response in an animal model of Ewing sarcoma.
    Investigative radiology, 2009, Volume: 44, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Neoplasms; Busulfan; Cell Line, Tumor; Diffusion Ma

2009
Prophylactic effect of bacteriophages on mice subjected to chemotherapy-induced immunosuppression and bone marrow transplant upon infection with Staphylococcus aureus.
    Medical microbiology and immunology, 2010, Volume: 199, Issue:2

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Granulocyt

2010
Platelets control leukocyte recruitment in a murine model of cutaneous arthus reaction.
    The American journal of pathology, 2010, Volume: 176, Issue:1

    Topics: Animals; Arthus Reaction; Blood Platelets; Busulfan; Cell Aggregation; Cell Count; Cell Movement; Ch

2010
Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration.
    Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 109, Issue:3

    Topics: Adult; Animals; Blood Platelets; Bronchoalveolar Lavage Fluid; Busulfan; CD18 Antigens; Cells, Cultu

2010
Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria.
    Journal of hepatology, 2011, Volume: 55, Issue:1

    Topics: Animals; Animals, Newborn; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Disease Pr

2011
Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.
    Clinical & developmental immunology, 2010, Volume: 2010

    Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; CD8-Positive T-Lymphocytes; Cyclophosphamide;

2010
Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.
    International journal of clinical and experimental pathology, 2011, Aug-15, Volume: 4, Issue:6

    Topics: Animals; Apoptosis; Bone Marrow Transplantation; Busulfan; Cell Transplantation; Cyclophosphamide; D

2011
[A novel severe aplastic anemia mouse model induced by IFN-γ plus busulphan].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2011, Volume: 32, Issue:11

    Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Female; Interferon-gamma; Mice; Mice, I

2011
Orthotopic grafting of cryopreserved prepubertal testicular tissue: in search of a simple yet effective cryopreservation protocol.
    Fertility and sterility, 2012, Volume: 97, Issue:5

    Topics: Animals; Busulfan; Cryopreservation; Disease Models, Animal; Fertility Preservation; Graft Survival;

2012
Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice.
    Fertility and sterility, 2012, Volume: 97, Issue:5

    Topics: Animals; Benzothiazoles; Busulfan; Disease Models, Animal; Feasibility Studies; Female; Fertility Pr

2012
Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval.
    The Journal of urology, 2012, Volume: 187, Issue:5

    Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Microdissect

2012
Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Anemia, Sickle Cell; Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Survival; Dis

2003
The effects of pretreatment with donor antigen and immunosuppressive agents on fully allogenic tracheal graft.
    The Journal of surgical research, 2004, Volume: 122, Issue:1

    Topics: Animals; Antigens; Bronchiolitis Obliterans; Busulfan; Cyclophosphamide; Disease Models, Animal; Imm

2004
Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:12

    Topics: Acids; Animals; Blood Platelets; Busulfan; Cell Adhesion; Cell Communication; Cells, Cultured; Disea

2006
Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.
    Journal of virology, 2007, Volume: 81, Issue:6

    Topics: Animals; Animals, Newborn; Antigens, CD34; B-Lymphocytes; Busulfan; Cobalt Radioisotopes; Cord Blood

2007
[Establishment of an animal model of azoospermia in male mice].
    Zhonghua nan ke xue = National journal of andrology, 2007, Volume: 13, Issue:2

    Topics: Animals; Azoospermia; Busulfan; Cyclophosphamide; Disease Models, Animal; Estradiol; Injections, Int

2007
Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: a common mechanism of disruption leads to divergent phenotypes.
    Development, growth & differentiation, 2007, Volume: 49, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Busulfan; Disease Models, A

2007
The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation.
    Bone marrow transplantation, 2007, Volume: 40, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disease Models,

2007
[Establishment of an animal model of oral mucositis induced by conditioning regimen of haematopoietic stem cell transplantation].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2007, Volume: 42, Issue:11

    Topics: Animals; Busulfan; Cyclophosphamide; Disease Models, Animal; Feasibility Studies; Hematopoietic Stem

2007
Serum FLT-3 ligand in a busulphan-induced model of chronic bone marrow hypoplasia in the female CD-1 mouse.
    International journal of experimental pathology, 2008, Volume: 89, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood Cell Count; Body Weight; Bone Marrow Cells; Bone M

2008
Comparison of conditioning regimens for alveolar macrophage reconstitution and innate immune function post bone marrow transplant.
    Experimental lung research, 2008, Volume: 34, Issue:5

    Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Busulfan; Dinoprostone; Disease

2008
Busulphan aplasia in rabbits: a model for human aplastic anaemia.
    British journal of haematology, 1982, Volume: 51, Issue:2

    Topics: Anemia, Aplastic; Animals; Bone Marrow; Busulfan; Disease Models, Animal; Erythrocyte Indices; Hemat

1982
[On an animal model of aplastic anemia induced by busulfan (author's transl)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1980, Volume: 43, Issue:5

    Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Female; Male; Mice

1980
Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion.
    Microvascular research, 1994, Volume: 47, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arterioles; Blood Platelets; Busulfan; Cyclooxygenase Inhibitor

1994
The influence of graft-versus-host reactivity, lymphocyte depletion, and cell dose on allogeneic bone marrow engraftment.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 3

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Dose-Respo

1993
Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation.
    Transplantation, 1996, Sep-27, Volume: 62, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Mo

1996
Ultrasound stimulation of rat testes damaged by busulfan.
    Ultrasound in medicine & biology, 1997, Volume: 23, Issue:9

    Topics: Alkylating Agents; Animals; Biomarkers; Busulfan; Disease Models, Animal; DNA; Epididymis; Epitheliu

1997
[The effect of the lysosomal function of circulating neutrophils on hemostasis and on the morphological changes in the internal organs in the disseminated intravascular coagulation syndrome].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 1999, Volume: 45, Issue:3

    Topics: Acid Phosphatase; Animals; Biomarkers; Busulfan; Disease Models, Animal; Disseminated Intravascular

1999
[A novel rat aplastic anemia model induced by 5-fluorouracil combined with busulfan].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2001, Volume: 22, Issue:4

    Topics: Anemia, Aplastic; Animals; Blood Cell Count; Busulfan; Disease Models, Animal; Female; Fluorouracil;

2001
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
    Acta haematologica, 1977, Volume: 57, Issue:4

    Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin;

1977
Immunologic abnormalities in an animal model of chronic hypoplastic marrow failure induced by busulfan.
    Blood, 1978, Volume: 51, Issue:4

    Topics: Anemia, Aplastic; Animals; Antibody-Producing Cells; B-Lymphocytes; Blood Cell Count; Busulfan; Chro

1978
Chronic hypoplastic marrow failure and residual injury.
    Blood cells, 1978, Volume: 4, Issue:1-2

    Topics: Anemia, Aplastic; Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Division; Chroni

1978
Residual marrow damage: possible explanation for idiosyncrasy to chloramphenicol.
    British journal of haematology, 1976, Volume: 32, Issue:4

    Topics: Anemia, Aplastic; Animals; Bone Marrow; Bone Marrow Cells; Busulfan; Cell Count; Chloramphenicol; Di

1976
A canine model for hepatic venoocclusive disease.
    Transplantation, 1992, Volume: 54, Issue:1

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Dogs; Hepatic Veno-Occlusive

1992
Systemic monoclonal antibody therapy for eliminating minimal residual leukemia in a rat bone marrow transplant model.
    Blood, 1989, Volume: 73, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cyclophosphamid

1989
Induction of hepatic veno-occlusive disease in dogs.
    The American journal of pathology, 1987, Volume: 126, Issue:1

    Topics: Animals; Busulfan; Buthionine Sulfoximine; Cyclophosphamide; Disease Models, Animal; Dog Diseases; D

1987
An animal model of haemolytic--uraemic syndrome in shigellosis: lipopolysaccharides of Shigella dysenteriae I and S. flexneri produce leucocyte-mediated renal cortical necrosis in rabbits.
    British journal of experimental pathology, 1985, Volume: 66, Issue:1

    Topics: Animals; Body Temperature; Busulfan; Creatinine; Disease Models, Animal; Dysentery, Bacillary; Endot

1985
Haemopoietic precursor cells in experimental hypoplastic marrow failure.
    The Australian journal of experimental biology and medical science, 1974, Volume: 52, Issue:6

    Topics: Anemia, Aplastic; Animals; Bone Marrow; Busulfan; Cell Count; Disease Models, Animal; Female; Granul

1974
Marrow transplantation in the busulfan-treated rat: preclinical model of aplastic anemia.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:6

    Topics: Anemia, Aplastic; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Chimera; Diseas

1974
An animal model of chronic aplastic marrow failure. I. Late marrow failure after busulfan.
    Blood, 1974, Volume: 44, Issue:1

    Topics: Anemia, Aplastic; Animals; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Busulfan; Disease Model

1974