busulfan has been researched along with Disease Models, Animal in 97 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
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"In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs." | 8.12 | Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022) |
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)." | 7.81 | [Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015) |
" We treated transgenic mice that over-express human mutant superoxide dismutase 1, a model of amyotrophic lateral sclerosis, with busulfan to determine whether this commonly used chemotherapeutic leads to stable chimerism and promotes the entry of bone marrow-derived cells into spinal cord." | 7.79 | Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. ( Barr, C; Humphries, RK; Krieger, C; Lewis, CA; Manning, J; Peake, K; Rossi, F, 2013) |
"Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes." | 5.51 | Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019) |
"Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available." | 5.43 | A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan. ( Abe, T; Hanazono, Y; Hishikawa, S; Kono, S; Kunita, S; Ohnuki, T, 2016) |
" In conclusion, although TH produced only a moderate effect against BCL1 leukemia when used alone, its combination with CY is promising and should be tested further in allogeneic murine models and clinical studies." | 5.34 | The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation. ( Abdul-Hai, A; Ergas, D; Resnick, IB; Shapira, MY; Slavin, S; Weiss, L, 2007) |
"In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs." | 4.12 | Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022) |
" We describe a protocol that involves pre-conditioning of Casper, a pigmentation mutant of zebrafish with busulfan that led to a higher rate of engraftment of hepatocellular carcinoma and acute myeloid leukemia cells." | 3.91 | An efficient method to generate xenograft tumor models of acute myeloid leukemia and hepatocellular carcinoma in adult zebrafish. ( Jayandharan, GR; Khan, N; Mahajan, NK; Sinha, P, 2019) |
"To develop a stable mouse model of acute graft-versus-host disease (aGVHD) by preconditioning with busulfan (BS)-cyclophospha mide (CP)." | 3.81 | [Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide]. ( Guo, K; He, X; Huang, Y; Wang, J; Xu, X; Ye, Y; Yi, W, 2015) |
"Busulfan is a chemotherapeutic drug that induces sterility, azoospermia and testicular atrophy." | 3.80 | Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol. ( Akhondi, MM; Jafarian, A; Lakpour, N; Pejhan, N; Sadeghi, MR; Salehkhou, S, 2014) |
" We treated transgenic mice that over-express human mutant superoxide dismutase 1, a model of amyotrophic lateral sclerosis, with busulfan to determine whether this commonly used chemotherapeutic leads to stable chimerism and promotes the entry of bone marrow-derived cells into spinal cord." | 3.79 | Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. ( Barr, C; Humphries, RK; Krieger, C; Lewis, CA; Manning, J; Peake, K; Rossi, F, 2013) |
"After establishing the feasibility of fiberoptic confocal fluorescent microscopy to identify antibody labeled sperm in vivo C57/B6 mice underwent intraperitoneal injection of busulfan to induce azoospermia." | 3.78 | Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval. ( Costabile, RA; Herr, JC; Kavoussi, PK; Lowe, GJ; Lysiak, JJ; Shetty, J; Smith, RP; Steers, WD, 2012) |
"To evaluate the potential of diffusion-weighted imaging (DWI) for monitoring dose-dependent tumor response in a mouse-xenograft model of Ewing sarcoma after administration of treosulfan in different dosages." | 3.75 | Diffusion-weighted imaging as predictor of therapy response in an animal model of Ewing sarcoma. ( Elverfeldt, DV; Juettner, E; Kontny, U; Reichardt, W; Uhl, M, 2009) |
"Development of experimental the syndrome of disseminated intravascular coagulation, DIC syndrome, in organism laboratory animals from affect preparation "EFA-2" by accompanied increase quantity of neutrophiles circulations, modifications of the lysosomal apparatus of neutrophiles the activity of the serum acid phosphatase increased, characteristic damage on hemostasis system and typical alteration in some organs." | 3.70 | [The effect of the lysosomal function of circulating neutrophils on hemostasis and on the morphological changes in the internal organs in the disseminated intravascular coagulation syndrome]. ( Boiarchuk, OD; Koval', SB; Lunina, NV, 1999) |
" Rats treated with busulfan to induce thrombocytopenia exhibited a 90% decrease in circulating platelets." | 3.69 | Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion. ( Lentsch, AB; Lindberg, RA; Miller, FN; Slaaf, DW, 1994) |
" In this study, cyclophosphamide combined with busulfan was used to establish an animal model." | 1.62 | Experimental study for the establishment of a chemotherapy-induced ovarian insufficiency model in rats by using cyclophosphamide combined with busulfan. ( Feng, X; Ling, L; Luo, Y; Tang, D; Wang, Y; Xiong, Z; Zhang, W, 2021) |
"Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes." | 1.51 | Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019) |
"Aplastic anemia was generated in mice with the administration of busulfan and cyclophosphamide followed by the characterization of the disease with peripheral blood hemogram, histopathological and cytochemical examinations of bone marrow." | 1.51 | Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population. ( Chatterjee, R; Law, S, 2019) |
" Conditioning with treosulfan alone at nonmyeloablative dosing (3." | 1.48 | Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease. ( Devadasan, D; Goldman, FD; Pawlik, KM; Sun, CW; Townes, TM; Westin, ER; Wu, LC, 2018) |
"Animal disease models have been criticized for lack of resemblance to human illnesses, hampering transfer of knowledge from preclinical research to clinical medicine." | 1.43 | A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation. ( Elezkurtaj, S; Kalupa, M; Penack, O; Riesner, K; Shi, Y, 2016) |
"Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available." | 1.43 | A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan. ( Abe, T; Hanazono, Y; Hishikawa, S; Kono, S; Kunita, S; Ohnuki, T, 2016) |
"Non-obstructive azoospermia is the most challenging type of male infertility." | 1.40 | Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model. ( He, D; Li, X; Lin, T; Liu, X; Peng, J; Wei, G; Zhang, D; Zhang, Y; Zhu, J, 2014) |
"Oral mucositis is one of the most debilitating side effects in patient undergoing chemotherapy or chemoradiotherapy." | 1.40 | Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis. ( Biswas, S; Nandakumar, K; Patel, A; Ramalingayya, GV; Shoja, MH, 2014) |
"Busulfan was used to induce testicular failure in 3-week-old immature FVB/NJNarl wild-type recipient mice." | 1.38 | Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice. ( Chen, CH; Hsu, MI; Huang, YH; Lai, WF; Tzeng, CR; Wang, CW, 2012) |
"To establish a novel severe aplastic anemia (SAA) mouse model by interferon-γ (IFN-γ) plus busulphan." | 1.37 | [A novel severe aplastic anemia mouse model induced by IFN-γ plus busulphan]. ( Chen, XF; Lin, ZH; Liu, H; Liu, HY; Ning, FY; Sun, F; Wang, H, 2011) |
"Busulfan treatment did not affect edema and hemorrhage in P-selectin- or PSGL-1-deficient mice, suggesting that the effect by busulfan is dependent on P-selectin and PSGL-1 expression." | 1.36 | Platelets control leukocyte recruitment in a murine model of cutaneous arthus reaction. ( Fujimoto, M; Hara, T; Hasegawa, M; Iwata, Y; Komura, K; Muroi, E; Ogawa, F; Sato, S; Shimizu, K; Takenaka, M; Yanaba, K, 2010) |
"Infantile malignant osteopetrosis is a fatal disease caused by lack of functional osteoclasts." | 1.35 | Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis. ( Askmyr, M; Ehinger, M; Flores, C; Hjalt, T; Holmberg, J; Richter, J, 2009) |
"In busulfan-treated embryos, diffuse cell death was evident in both ectoderm and mesoderm, peaking at E13." | 1.34 | Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: a common mechanism of disruption leads to divergent phenotypes. ( Naruse, T; Oberg, KC; Ogino, T; Takagi, M; Takahara, M, 2007) |
" In conclusion, although TH produced only a moderate effect against BCL1 leukemia when used alone, its combination with CY is promising and should be tested further in allogeneic murine models and clinical studies." | 1.34 | The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation. ( Abdul-Hai, A; Ergas, D; Resnick, IB; Shapira, MY; Slavin, S; Weiss, L, 2007) |
"The incidence of oral mucositis in model group was as high as 80." | 1.34 | [Establishment of an animal model of oral mucositis induced by conditioning regimen of haematopoietic stem cell transplantation]. ( Chen, XB; Tong, XZ; Wang, X, 2007) |
"To develop an aplastic anemia model with hematopoietic stem cell failure in rats." | 1.31 | [A novel rat aplastic anemia model induced by 5-fluorouracil combined with busulfan]. ( Chu, J; Ding, S; Liu, A; Wang, S; Xu, S; Zhao, J, 2001) |
"BUF rats suffering from severe relapsing experimental autoimmune encephalomyelitis (R-EAE), a model for multiple sclerosis, were treated with intensive cytoreductive therapy and grafting of allogeneic bone marrow (BM)." | 1.29 | Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation. ( Mulder, AH; van Bekkum, DW; van Gelder, M, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (13.40) | 18.7374 |
1990's | 6 (6.19) | 18.2507 |
2000's | 18 (18.56) | 29.6817 |
2010's | 45 (46.39) | 24.3611 |
2020's | 15 (15.46) | 2.80 |
Authors | Studies |
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Abrams, RPM | 1 |
Yasgar, A | 1 |
Teramoto, T | 1 |
Lee, MH | 1 |
Dorjsuren, D | 1 |
Eastman, RT | 1 |
Malik, N | 1 |
Zakharov, AV | 1 |
Li, W | 1 |
Bachani, M | 1 |
Brimacombe, K | 1 |
Steiner, JP | 1 |
Hall, MD | 1 |
Balasubramanian, A | 1 |
Jadhav, A | 1 |
Padmanabhan, R | 1 |
Simeonov, A | 1 |
Nath, A | 1 |
Ganjibakhsh, M | 1 |
Mehraein, F | 1 |
Koruji, M | 1 |
Bashiri, Z | 1 |
Jiang, S | 1 |
Xu, Y | 1 |
Fan, Y | 1 |
Hu, Y | 1 |
Zhang, Q | 2 |
Su, W | 1 |
Mobarak, H | 1 |
Rahbarghazi, R | 1 |
Nouri, M | 1 |
Heidarpour, M | 1 |
Mahdipour, M | 1 |
Hao, Y | 1 |
Fang, H | 1 |
Yan, X | 1 |
Shen, W | 2 |
Liu, J | 1 |
Han, P | 1 |
Zhao, Y | 2 |
Zhang, W | 2 |
Feng, Y | 1 |
Ziaeipour, S | 1 |
Rezaei, F | 1 |
Piryaei, A | 1 |
Abdi, S | 1 |
Moradi, A | 1 |
Ghasemi, A | 1 |
Azad, N | 1 |
Abdollahifar, MA | 2 |
Lei, B | 1 |
Xie, L | 1 |
Zhang, S | 1 |
Lv, D | 1 |
Shu, F | 1 |
Deng, Y | 1 |
Luo, Q | 1 |
Liu, R | 1 |
Wang, L | 1 |
Hou, Y | 1 |
Zhang, H | 1 |
Xie, Y | 1 |
Chen, H | 2 |
Luo, D | 1 |
Yang, X | 1 |
Yao, J | 1 |
Zhang, C | 1 |
Lv, L | 1 |
Guo, Z | 1 |
Deng, C | 3 |
Li, Y | 2 |
Liang, X | 1 |
Sun, X | 1 |
Liu, G | 1 |
Qu, N | 1 |
Kuramasu, M | 1 |
Nagahori, K | 1 |
Ogawa, Y | 1 |
Hayashi, S | 1 |
Hirayanagi, Y | 1 |
Terayama, H | 1 |
Suyama, K | 1 |
Sakabe, K | 1 |
Itoh, M | 1 |
Jia, W | 1 |
Zhen, M | 1 |
Li, L | 2 |
Zhou, C | 1 |
Sun, Z | 2 |
Liu, S | 2 |
Zhao, Z | 1 |
Li, J | 3 |
Wang, C | 1 |
Bai, C | 1 |
Yu, S | 1 |
Zhang, FL | 1 |
Li, YQ | 1 |
Sun, ZY | 1 |
Ebrahimi, V | 1 |
Aliaghaei, A | 1 |
Raoofi, A | 1 |
Khosravi, A | 1 |
Hasani, A | 1 |
Mehdizadeh, A | 1 |
Asadi, M | 1 |
Chen, C | 2 |
Li, S | 1 |
Hu, C | 1 |
Cao, W | 1 |
Fu, Q | 1 |
Zheng, L | 1 |
Huang, J | 1 |
Chen, Z | 1 |
Liu, M | 1 |
Hu, JH | 1 |
Gao, Y | 1 |
Jiang, MH | 1 |
Tang, D | 1 |
Feng, X | 1 |
Ling, L | 1 |
Luo, Y | 1 |
Wang, Y | 1 |
Xiong, Z | 1 |
Burdette, AJ | 1 |
Andrew Pratt, G | 1 |
Campagna, MV | 1 |
Sheppard, FR | 1 |
Chatterjee, R | 2 |
Law, S | 2 |
Llewellyn, GN | 1 |
Alvarez-Carbonell, D | 1 |
Chateau, M | 1 |
Karn, J | 1 |
Cannon, PM | 1 |
Dighe, NM | 1 |
Tan, KW | 1 |
Tan, LG | 1 |
Shaw, SSW | 1 |
Buckley, SMK | 1 |
Sandikin, D | 1 |
Johana, N | 1 |
Tan, YW | 1 |
Biswas, A | 1 |
Choolani, M | 1 |
Waddington, SN | 1 |
Antoniou, MN | 1 |
Chan, JKY | 1 |
Mattar, CNZ | 1 |
Devadasan, D | 1 |
Sun, CW | 1 |
Westin, ER | 1 |
Wu, LC | 1 |
Pawlik, KM | 1 |
Townes, TM | 1 |
Goldman, FD | 1 |
Huang, Y | 3 |
Zhao, L | 1 |
Yao, C | 1 |
Yang, C | 1 |
Zhu, Z | 1 |
Li, P | 1 |
Tian, R | 1 |
He, Z | 1 |
Li, Z | 1 |
Chen, QH | 1 |
Wang, J | 2 |
Lin, SF | 1 |
Xue, HM | 1 |
Kadam, P | 1 |
Ntemou, E | 1 |
Baert, Y | 2 |
Van Laere, S | 1 |
Van Saen, D | 2 |
Goossens, E | 2 |
Manshadi, MD | 1 |
Navid, S | 1 |
Hoshino, Y | 1 |
Daneshi, E | 1 |
Noory, P | 1 |
Abbasi, M | 1 |
Khan, N | 1 |
Mahajan, NK | 1 |
Sinha, P | 1 |
Jayandharan, GR | 1 |
Liu, Y | 2 |
Wu, X | 2 |
Jiang, H | 1 |
Guo, X | 1 |
Yin, X | 1 |
Zhu, W | 1 |
Pan, Y | 1 |
Wang, H | 2 |
Liang, Y | 2 |
Zhu, X | 1 |
Cai, YT | 1 |
Xiong, CL | 1 |
Shen, SL | 1 |
Rao, JP | 1 |
Liu, TS | 1 |
Qiu, F | 1 |
Skaznik-Wikiel, ME | 1 |
McGuire, MM | 1 |
Sukhwani, M | 1 |
Donohue, J | 1 |
Chu, T | 1 |
Krivak, TC | 1 |
Rajkovic, A | 1 |
Orwig, KE | 1 |
Lewis, CA | 1 |
Manning, J | 1 |
Barr, C | 1 |
Peake, K | 1 |
Humphries, RK | 1 |
Rossi, F | 1 |
Krieger, C | 1 |
Li, JP | 1 |
Guo, WB | 1 |
He, JC | 1 |
Yu, QF | 1 |
Wu, XQ | 1 |
Mao, XM | 1 |
Zhang, FB | 1 |
Jy, W | 1 |
Johansen, ME | 1 |
Bidot, C | 1 |
Horstman, LL | 1 |
Ahn, YS | 1 |
Gutti, TL | 1 |
Knibbe, JS | 1 |
Makarov, E | 1 |
Zhang, J | 1 |
Yannam, GR | 1 |
Gorantla, S | 2 |
Sun, Y | 1 |
Mercer, DF | 1 |
Suemizu, H | 1 |
Wisecarver, JL | 1 |
Osna, NA | 1 |
Bronich, TK | 1 |
Poluektova, LY | 1 |
Jafarian, A | 1 |
Sadeghi, MR | 1 |
Pejhan, N | 1 |
Salehkhou, S | 1 |
Lakpour, N | 1 |
Akhondi, MM | 1 |
Zhang, D | 1 |
Liu, X | 1 |
Peng, J | 1 |
He, D | 1 |
Lin, T | 1 |
Zhu, J | 1 |
Li, X | 2 |
Zhang, Y | 2 |
Wei, G | 1 |
Kanaji, S | 1 |
Fahs, SA | 1 |
Ware, J | 1 |
Montgomery, RR | 1 |
Shi, Q | 1 |
Patel, A | 1 |
Biswas, S | 1 |
Shoja, MH | 1 |
Ramalingayya, GV | 1 |
Nandakumar, K | 1 |
Chen, YF | 1 |
Zhao, ZQ | 1 |
Wu, ZM | 1 |
Zou, ZY | 1 |
Luo, XJ | 1 |
Xie, C | 1 |
Li, N | 1 |
Hu, W | 1 |
Yang, W | 1 |
Chen, P | 1 |
Chen, Y | 1 |
Lai, D | 1 |
Wang, F | 1 |
Yao, X | 1 |
Xiang, C | 1 |
Riesner, K | 1 |
Kalupa, M | 1 |
Shi, Y | 1 |
Elezkurtaj, S | 1 |
Penack, O | 1 |
Qiao, J | 1 |
Xia, Y | 1 |
Chu, P | 1 |
Yao, H | 1 |
Xu, L | 1 |
Qi, K | 1 |
Xu, K | 1 |
Zeng, L | 1 |
He, X | 1 |
Xu, X | 1 |
Yi, W | 1 |
Ye, Y | 1 |
Guo, K | 1 |
Rathe, M | 1 |
Thomassen, M | 1 |
Shen, RL | 1 |
Pontoppidan, PE | 1 |
Husby, S | 1 |
Müller, K | 1 |
Kruse, TA | 1 |
Sangild, PT | 1 |
Abe, T | 1 |
Kono, S | 1 |
Ohnuki, T | 1 |
Hishikawa, S | 1 |
Kunita, S | 1 |
Hanazono, Y | 1 |
Zhang, T | 1 |
Yan, D | 1 |
Yang, Y | 1 |
Ma, A | 1 |
Wang, Z | 1 |
Pan, Q | 1 |
Hu, P | 1 |
Nikolaishvili-Feinberg, N | 1 |
Scesa, G | 1 |
Bi, Y | 1 |
Pan, D | 1 |
Moore, D | 1 |
Bongarzone, ER | 1 |
Sands, MS | 1 |
Miller, R | 1 |
Kafri, T | 1 |
Wu, C | 1 |
Shen, Q | 1 |
Zhou, Z | 1 |
Liu, W | 1 |
Hua, J | 1 |
Horn, MM | 1 |
Paz, AH | 1 |
Duarte, ME | 1 |
Baldo, G | 1 |
Belardinelli, MC | 1 |
Matte, U | 1 |
Lima, EO | 1 |
Passos, EP | 1 |
Sadeghi, B | 3 |
Aghdami, N | 1 |
Hassan, Z | 3 |
Forouzanfar, M | 1 |
Rozell, B | 3 |
Abedi-Valugerdi, M | 2 |
Hassan, M | 3 |
Enquist, IB | 1 |
Nilsson, E | 1 |
Månsson, JE | 1 |
Ehinger, M | 2 |
Richter, J | 2 |
Karlsson, S | 1 |
Askmyr, M | 1 |
Holmberg, J | 1 |
Flores, C | 1 |
Hjalt, T | 1 |
Peranteau, WH | 1 |
Heaton, TE | 1 |
Gu, YC | 1 |
Volk, SW | 1 |
Bauer, TR | 1 |
Alcorn, K | 1 |
Tuschong, LM | 1 |
Johnson, MP | 1 |
Hickstein, DD | 1 |
Flake, AW | 1 |
Reichardt, W | 1 |
Juettner, E | 1 |
Uhl, M | 1 |
Elverfeldt, DV | 1 |
Kontny, U | 1 |
Zimecki, M | 1 |
Artym, J | 1 |
Kocieba, M | 1 |
Weber-Dabrowska, B | 1 |
Borysowski, J | 1 |
Górski, A | 1 |
Hara, T | 1 |
Shimizu, K | 1 |
Ogawa, F | 1 |
Yanaba, K | 1 |
Iwata, Y | 1 |
Muroi, E | 1 |
Takenaka, M | 1 |
Komura, K | 1 |
Hasegawa, M | 1 |
Fujimoto, M | 1 |
Sato, S | 1 |
Kornerup, KN | 1 |
Salmon, GP | 1 |
Pitchford, SC | 1 |
Liu, WL | 1 |
Page, CP | 1 |
Duchartre, Y | 1 |
Petit, N | 1 |
Moya, C | 1 |
Lalanne, M | 1 |
Dubus, P | 1 |
Verneuil, Hd | 1 |
Moreau-Gaudry, F | 1 |
Richard, E | 1 |
Al-Hashmi, S | 2 |
Concha, H | 1 |
Lundmark, C | 1 |
Grönvik, KO | 1 |
Ning, FY | 1 |
Lin, ZH | 1 |
Liu, H | 1 |
Chen, XF | 1 |
Sun, F | 1 |
Liu, HY | 1 |
Ning, L | 1 |
in't Veld, P | 1 |
Tournaye, H | 1 |
Chen, CH | 1 |
Wang, CW | 1 |
Hsu, MI | 1 |
Huang, YH | 1 |
Lai, WF | 1 |
Tzeng, CR | 1 |
Smith, RP | 1 |
Lowe, GJ | 1 |
Kavoussi, PK | 1 |
Steers, WD | 1 |
Costabile, RA | 1 |
Herr, JC | 1 |
Shetty, J | 1 |
Lysiak, JJ | 1 |
Kean, LS | 1 |
Manci, EA | 1 |
Perry, J | 1 |
Balkan, C | 1 |
Coley, S | 1 |
Holtzclaw, D | 1 |
Adams, AB | 1 |
Larsen, CP | 1 |
Hsu, LL | 1 |
Archer, DR | 1 |
Suemitsu, R | 1 |
Yoshino, I | 1 |
Shoji, F | 1 |
Yamaguchi, M | 1 |
Tomita, Y | 1 |
Maehara, Y | 1 |
Chen, J | 1 |
Zarbock, A | 1 |
Singbartl, K | 1 |
Ley, K | 1 |
Sneller, H | 1 |
Walters, L | 1 |
Sharp, JG | 1 |
Pirruccello, SJ | 1 |
West, JT | 1 |
Wood, C | 1 |
Dewhurst, S | 1 |
Gendelman, HE | 1 |
Poluektova, L | 1 |
Huang, XB | 1 |
Li, HG | 1 |
Naruse, T | 1 |
Takahara, M | 1 |
Takagi, M | 1 |
Oberg, KC | 1 |
Ogino, T | 1 |
Abdul-Hai, A | 1 |
Weiss, L | 1 |
Ergas, D | 1 |
Resnick, IB | 1 |
Slavin, S | 1 |
Shapira, MY | 1 |
Chen, XB | 1 |
Wang, X | 1 |
Tong, XZ | 1 |
Molyneux, G | 1 |
Gibson, FM | 1 |
Whayman, M | 1 |
Turton, JA | 1 |
Hubbard, LL | 1 |
Ballinger, MN | 1 |
Wilke, CA | 1 |
Moore, BB | 1 |
Haak, HL | 2 |
den Ottolander, GJ | 1 |
te Velde, J | 1 |
Veenhof, W | 1 |
Kleiverda, K | 1 |
Spaander, PJ | 1 |
Yamagishi, M | 1 |
Niki, T | 1 |
Hiraoka, A | 1 |
Dohmae, N | 1 |
Uchino, H | 1 |
Lindberg, RA | 1 |
Slaaf, DW | 1 |
Lentsch, AB | 1 |
Miller, FN | 1 |
Glass, B | 1 |
Uharek, L | 1 |
Gaska, T | 1 |
Gassmann, W | 1 |
Löffler, H | 1 |
Müller-Ruchholtz, W | 1 |
van Gelder, M | 1 |
Mulder, AH | 1 |
van Bekkum, DW | 1 |
Haddad, S | 1 |
Carvalho, TL | 1 |
Anselmo-Franci, JA | 1 |
Petenusci, SO | 1 |
Favaretto, AL | 1 |
Koval', SB | 1 |
Boiarchuk, OD | 1 |
Lunina, NV | 1 |
Zhao, J | 1 |
Chu, J | 1 |
Ding, S | 1 |
Xu, S | 1 |
Liu, A | 1 |
Wang, S | 1 |
Greenberger, JS | 1 |
Bocaccino, CA | 1 |
Szot, SJ | 1 |
Moloney, WC | 1 |
Pugsley, CA | 1 |
Forbes, IJ | 1 |
Morley, AA | 2 |
Trainor, KJ | 1 |
Seshadri, RS | 1 |
Morley, A | 3 |
Trainor, K | 1 |
Remes, J | 1 |
Epstein, RB | 1 |
Min, KW | 1 |
Anderson, SL | 1 |
Syzek, L | 1 |
Wagner, JE | 1 |
Johnson, RJ | 1 |
Santos, GW | 2 |
Kim, BK | 1 |
Shin, HS | 1 |
Shulman, HM | 1 |
Luk, K | 1 |
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Butler, T | 1 |
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Al-Mahmud, KA | 1 |
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Rahman, MM | 1 |
Blake, J | 2 |
Tutschka, PJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Filgrastim for Treatment of Premature Ovarian Insufficiency: Randomized Clinical Trial[NCT02783937] | Phase 4 | 10 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965] | 350 participants (Anticipated) | Observational | 2018-08-15 | Active, not recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for busulfan and Disease Models, Animal
Article | Year |
---|---|
Animal models for acquired bone marrow failure syndromes.
Topics: Anemia, Aplastic; Animals; Benzene; Bone Marrow Diseases; Busulfan; Chloramphenicol; Disease Models, | 2005 |
Experimental drug-induced aplastic anaemia.
Topics: Anemia, Aplastic; Animals; Benzene; Busulfan; Chloramphenicol; Colony-Forming Units Assay; Disease M | 1980 |
95 other studies available for busulfan and Disease Models, Animal
Article | Year |
---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The therapeutic potential of adipose tissue-derived mesenchymal stromal cells in the treatment of busulfan-induced azoospermic mice.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Immunosuppressive Agents; Male; Mesenchymal | 2022 |
Busulfan impairs blood-testis barrier and spermatogenesis by increasing noncollagenous 1 domain peptide via matrix metalloproteinase 9.
Topics: Animals; Antineoplastic Agents, Alkylating; Autoantigens; Blood-Testis Barrier; Busulfan; Cell Membr | 2022 |
Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Humans; Injections; Injections, Intraperiton | 2022 |
Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model.
Topics: Alginates; Animals; Anti-Inflammatory Agents; Busulfan; Disease Models, Animal; Liver; Mice; Oligosa | 2023 |
Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Fever; Male; Mice; Organ Size; Sperm Count; | 2019 |
UBE2W down-regulation promotes cell apoptosis and correlates with hypospermatogenesis.
Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Dimethyl Sulfoxide; Disease Models, Animal; Do | 2020 |
The Effects of Inhibin B in the Chemotherapy Drug-Induced Premature Ovarian Insufficiency Mice and hPMSCs Treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Busulfan; Cyclophosphamide; Disease Models, Animal; Femal | 2020 |
Inhibiting Necroptosis of Spermatogonial Stem Cell as a Novel Strategy for Male Fertility Preservation.
Topics: Animals; Busulfan; Cryopreservation; Disease Models, Animal; Fertility Preservation; Male; Mice; Mic | 2020 |
Co-Administration of the Traditional Medicines Hachimi-Jio-Gan and Hochu-Ekki-To Can Reverse Busulfan-Induced Aspermatogenesis.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Body Weight; Busulfan; Cell Proliferation; Di | 2020 |
Gadofullerene nanoparticles for robust treatment of aplastic anemia induced by chemotherapy drugs.
Topics: Anemia, Aplastic; Animals; Antineoplastic Agents, Alkylating; Bone Marrow Cells; Busulfan; Cell Diff | 2020 |
Chestnut polysaccharides benefit spermatogenesis through improvement in the expression of important genes.
Topics: Animals; Busulfan; Disease Models, Animal; Drugs, Chinese Herbal; Fagaceae; Gene Expression Regulati | 2020 |
Protective effect of curcumin on busulfan-induced renal toxicity in male rats.
Topics: Animals; Antioxidants; Busulfan; Curcumin; Disease Models, Animal; Injections, Intravenous; Kidney D | 2020 |
Protective Effects of Puerarin on Premature Ovarian Failure via Regulation of Wnt/β-catenin Signaling Pathway and Oxidative Stress.
Topics: Animals; Apoptosis; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Isoflavones; Mice; O | 2021 |
Substance P restores spermatogenesis in busulfan-treated mice: A new strategy for male infertility therapy.
Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Ex | 2021 |
Experimental study for the establishment of a chemotherapy-induced ovarian insufficiency model in rats by using cyclophosphamide combined with busulfan.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan; Cyclophosphamide; Disea | 2021 |
Evaluation of a new generation platelet-derived hemostatic agent in a rabbit thrombocytopenic model.
Topics: Animals; Blood Platelets; Busulfan; Disease Models, Animal; Hemostatics; Humans; Rabbits; Thrombocyt | 2017 |
Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia.
Topics: Anemia, Aplastic; Animals; Apoptosis; Bone Marrow; Busulfan; Chemokine CXCL12; Cyclophosphamide; Dis | 2018 |
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.
Topics: AIDS Dementia Complex; Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Busulfan; Cell Differenti | 2018 |
A comparison of intrauterine hemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassemia in a HbbTh3/+ murine model.
Topics: Animals; beta-Thalassemia; Bone Marrow Transplantation; Busulfan; Cell Survival; Cellular Microenvir | 2018 |
Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease.
Topics: Anemia, Sickle Cell; Animals; Antibodies; Antineoplastic Agents, Alkylating; Bone Marrow Transplanta | 2018 |
Effect of Kallikrein-related Peptidase KLK1 on Ameliorating Spermatogenesis Regeneration in Busulfan-induced Azoospermic Mice and Promoting Mouse Spermatogonial Stem Cell Proliferation In Vitro.
Topics: Animals; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Humans; Injec | 2018 |
[Relationship of Blimp-1 Hypoexpression with Pathogenesis of Aplastic Anemia].
Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Mice; Positive Regulatory Domain I-Bind | 2018 |
Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice.
Topics: Adult Germline Stem Cells; Animals; Busulfan; Cadmium Chloride; Cell Survival; Disease Models, Anima | 2018 |
The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure.
Topics: Animals; Anti-Mullerian Hormone; Busulfan; Cell Transplantation; Disease Models, Animal; Female; Fol | 2019 |
An efficient method to generate xenograft tumor models of acute myeloid leukemia and hepatocellular carcinoma in adult zebrafish.
Topics: Animals; Busulfan; Carcinoma, Hepatocellular; Cell Compartmentation; Disease Models, Animal; Heterog | 2019 |
Raman spectroscopic analysis of testicular lamina propria predicts spermatogenesis in a mouse infertility model.
Topics: Animals; Busulfan; Disease Models, Animal; Infertility, Male; Male; Mice; Mucous Membrane; Seminifer | 2019 |
Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population.
Topics: Anemia, Aplastic; Animals; Apoptosis; Busulfan; Cell Proliferation; Cellular Senescence; Disease Mod | 2019 |
The Preconditioning of Busulfan Promotes Efficiency of Human CD133+ Cells Engraftment in NOD Shi-SCID IL2Rγcnull (NOG) Mice via Intra-Bone Marrow Injection.
Topics: AC133 Antigen; Animals; Busulfan; Cell Differentiation; Disease Models, Animal; Female; Flow Cytomet | 2019 |
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
Topics: Animals; Apoptosis; Blood-Testis Barrier; Busulfan; Cadherins; Cell Adhesion; Culture Media, Conditi | 2019 |
Granulocyte colony-stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disease Models, | 2013 |
Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Ce | 2013 |
[Establishing a mouse model of Sertoli-cell-only syndrome by administration of busulfan].
Topics: Animals; Busulfan; Cold Temperature; Disease Models, Animal; Male; Mice; Mice, Inbred Strains; Organ | 2013 |
Red cell-derived microparticles (RMP) as haemostatic agent.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation Disorders; Busulfan; Cell Separatio | 2013 |
Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; Coinfection; Disease Models, Animal; Hematopoi | 2014 |
Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol.
Topics: Animals; Azoospermia; Busulfan; Cyclin B1; Disease Models, Animal; Estradiol; Follicle Stimulating H | 2014 |
Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model.
Topics: Animals; Antineoplastic Agents; Azoospermia; Bone Marrow Cells; Busulfan; Cell Transdifferentiation; | 2014 |
Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome.
Topics: Animals; Bernard-Soulier Syndrome; Bleeding Time; Busulfan; Disease Models, Animal; Gene Transfer Te | 2014 |
Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis.
Topics: Animals; Body Weight; Busulfan; Chromatography, High Pressure Liquid; Disease Models, Animal; Feedin | 2014 |
The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice.
Topics: Anemia, Aplastic; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Busulfan; Cyclophos | 2014 |
[Establishment of a graft-versus-host disease mouse model for haplo-identical bone marrow transplantation with busulfan and fludarabine conditioning regimen].
Topics: Animals; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Drug Combinations; Graft vs | 2015 |
Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure.
Topics: Adult; Animals; Body Weight; Busulfan; Cell Differentiation; Cyclophosphamide; Disease Models, Anima | 2015 |
A preclinical acute GVHD mouse model based on chemotherapy conditioning and MHC-matched transplantation.
Topics: Acute Disease; Allografts; Animals; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Graf | 2016 |
Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation.
Topics: Adenosine Triphosphate; Animals; Busulfan; Carrier Proteins; Chemical and Drug Induced Liver Injury; | 2015 |
[Establishment of a mouse model of acute graft-versus-host disease by busulfan combined with cyclophosphamide].
Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Female; Gr | 2015 |
Chemotherapy Modulates Intestinal Immune Gene Expression Including Surfactant Protein-D and Deleted in Malignant Brain Tumors 1 in Piglets.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Busulfan; Cyclophosphamide; Disease Models, Animal; | 2016 |
A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan.
Topics: Acute Disease; Animals; Antineoplastic Agents, Alkylating; Bleeding Time; Busulfan; Disease Models, | 2016 |
The comparison of animal models for premature ovarian failure established by several different source of inducers.
Topics: Animals; Busulfan; Cisplatin; Cyclohexenes; Cyclophosphamide; Disease Models, Animal; Dose-Response | 2016 |
Hematopoietic Stem cell transplantation and lentiviral vector-based gene therapy for Krabbe's disease: Present convictions and future prospects.
Topics: Animals; Antigens, CD; Antimetabolites; Brain; Busulfan; Cell Line, Transformed; Cycloserine; Diseas | 2016 |
Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse.
Topics: Adult Germline Stem Cells; Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; | 2016 |
Germinative testicular cells and bone marrow mononuclear cells transplanted to a rat model of testicular degeneration.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Germ Cell | 2008 |
GVHD after chemotherapy conditioning in allogeneic transplanted mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan | 2008 |
Successful low-risk hematopoietic cell therapy in a mouse model of type 1 Gaucher disease.
Topics: Animals; Bone Marrow; Busulfan; Cell- and Tissue-Based Therapy; Disease Models, Animal; Flow Cytomet | 2009 |
Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis.
Topics: Animals; Animals, Newborn; Blindness; Busulfan; Disease Models, Animal; Hematopoiesis; Humans; Infan | 2009 |
Haploidentical in utero hematopoietic cell transplantation improves phenotype and can induce tolerance for postnatal same-donor transplants in the canine leukocyte adhesion deficiency model.
Topics: Animals; Busulfan; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dogs; Female; Fetal T | 2009 |
Diffusion-weighted imaging as predictor of therapy response in an animal model of Ewing sarcoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Bone Neoplasms; Busulfan; Cell Line, Tumor; Diffusion Ma | 2009 |
Prophylactic effect of bacteriophages on mice subjected to chemotherapy-induced immunosuppression and bone marrow transplant upon infection with Staphylococcus aureus.
Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Granulocyt | 2010 |
Platelets control leukocyte recruitment in a murine model of cutaneous arthus reaction.
Topics: Animals; Arthus Reaction; Blood Platelets; Busulfan; Cell Aggregation; Cell Count; Cell Movement; Ch | 2010 |
Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration.
Topics: Adult; Animals; Blood Platelets; Bronchoalveolar Lavage Fluid; Busulfan; CD18 Antigens; Cells, Cultu | 2010 |
Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria.
Topics: Animals; Animals, Newborn; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Disease Pr | 2011 |
Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.
Topics: Animals; Antineoplastic Agents, Alkylating; Busulfan; CD8-Positive T-Lymphocytes; Cyclophosphamide; | 2010 |
Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.
Topics: Animals; Apoptosis; Bone Marrow Transplantation; Busulfan; Cell Transplantation; Cyclophosphamide; D | 2011 |
[A novel severe aplastic anemia mouse model induced by IFN-γ plus busulphan].
Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Female; Interferon-gamma; Mice; Mice, I | 2011 |
Orthotopic grafting of cryopreserved prepubertal testicular tissue: in search of a simple yet effective cryopreservation protocol.
Topics: Animals; Busulfan; Cryopreservation; Disease Models, Animal; Fertility Preservation; Graft Survival; | 2012 |
Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice.
Topics: Animals; Benzothiazoles; Busulfan; Disease Models, Animal; Feasibility Studies; Female; Fertility Pr | 2012 |
Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Microdissect | 2012 |
Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Survival; Dis | 2003 |
The effects of pretreatment with donor antigen and immunosuppressive agents on fully allogenic tracheal graft.
Topics: Animals; Antigens; Bronchiolitis Obliterans; Busulfan; Cyclophosphamide; Disease Models, Animal; Imm | 2004 |
Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation.
Topics: Acids; Animals; Blood Platelets; Busulfan; Cell Adhesion; Cell Communication; Cells, Cultured; Disea | 2006 |
Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.
Topics: Animals; Animals, Newborn; Antigens, CD34; B-Lymphocytes; Busulfan; Cobalt Radioisotopes; Cord Blood | 2007 |
[Establishment of an animal model of azoospermia in male mice].
Topics: Animals; Azoospermia; Busulfan; Cyclophosphamide; Disease Models, Animal; Estradiol; Injections, Int | 2007 |
Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: a common mechanism of disruption leads to divergent phenotypes.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Busulfan; Disease Models, A | 2007 |
The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disease Models, | 2007 |
[Establishment of an animal model of oral mucositis induced by conditioning regimen of haematopoietic stem cell transplantation].
Topics: Animals; Busulfan; Cyclophosphamide; Disease Models, Animal; Feasibility Studies; Hematopoietic Stem | 2007 |
Serum FLT-3 ligand in a busulphan-induced model of chronic bone marrow hypoplasia in the female CD-1 mouse.
Topics: Animals; Antineoplastic Agents, Alkylating; Blood Cell Count; Body Weight; Bone Marrow Cells; Bone M | 2008 |
Comparison of conditioning regimens for alveolar macrophage reconstitution and innate immune function post bone marrow transplant.
Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Busulfan; Dinoprostone; Disease | 2008 |
Busulphan aplasia in rabbits: a model for human aplastic anaemia.
Topics: Anemia, Aplastic; Animals; Bone Marrow; Busulfan; Disease Models, Animal; Erythrocyte Indices; Hemat | 1982 |
[On an animal model of aplastic anemia induced by busulfan (author's transl)].
Topics: Anemia, Aplastic; Animals; Busulfan; Disease Models, Animal; Female; Male; Mice | 1980 |
Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion.
Topics: Amino Acid Oxidoreductases; Animals; Arterioles; Blood Platelets; Busulfan; Cyclooxygenase Inhibitor | 1994 |
The influence of graft-versus-host reactivity, lymphocyte depletion, and cell dose on allogeneic bone marrow engraftment.
Topics: Animals; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Models, Animal; Dose-Respo | 1993 |
Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation.
Topics: Animals; Antibodies, Monoclonal; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease Mo | 1996 |
Ultrasound stimulation of rat testes damaged by busulfan.
Topics: Alkylating Agents; Animals; Biomarkers; Busulfan; Disease Models, Animal; DNA; Epididymis; Epitheliu | 1997 |
[The effect of the lysosomal function of circulating neutrophils on hemostasis and on the morphological changes in the internal organs in the disseminated intravascular coagulation syndrome].
Topics: Acid Phosphatase; Animals; Biomarkers; Busulfan; Disease Models, Animal; Disseminated Intravascular | 1999 |
[A novel rat aplastic anemia model induced by 5-fluorouracil combined with busulfan].
Topics: Anemia, Aplastic; Animals; Blood Cell Count; Busulfan; Disease Models, Animal; Female; Fluorouracil; | 2001 |
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; | 1977 |
Immunologic abnormalities in an animal model of chronic hypoplastic marrow failure induced by busulfan.
Topics: Anemia, Aplastic; Animals; Antibody-Producing Cells; B-Lymphocytes; Blood Cell Count; Busulfan; Chro | 1978 |
Chronic hypoplastic marrow failure and residual injury.
Topics: Anemia, Aplastic; Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Division; Chroni | 1978 |
Residual marrow damage: possible explanation for idiosyncrasy to chloramphenicol.
Topics: Anemia, Aplastic; Animals; Bone Marrow; Bone Marrow Cells; Busulfan; Cell Count; Chloramphenicol; Di | 1976 |
A canine model for hepatic venoocclusive disease.
Topics: Animals; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Dogs; Hepatic Veno-Occlusive | 1992 |
Systemic monoclonal antibody therapy for eliminating minimal residual leukemia in a rat bone marrow transplant model.
Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cyclophosphamid | 1989 |
Induction of hepatic veno-occlusive disease in dogs.
Topics: Animals; Busulfan; Buthionine Sulfoximine; Cyclophosphamide; Disease Models, Animal; Dog Diseases; D | 1987 |
An animal model of haemolytic--uraemic syndrome in shigellosis: lipopolysaccharides of Shigella dysenteriae I and S. flexneri produce leucocyte-mediated renal cortical necrosis in rabbits.
Topics: Animals; Body Temperature; Busulfan; Creatinine; Disease Models, Animal; Dysentery, Bacillary; Endot | 1985 |
Haemopoietic precursor cells in experimental hypoplastic marrow failure.
Topics: Anemia, Aplastic; Animals; Bone Marrow; Busulfan; Cell Count; Disease Models, Animal; Female; Granul | 1974 |
Marrow transplantation in the busulfan-treated rat: preclinical model of aplastic anemia.
Topics: Anemia, Aplastic; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Busulfan; Chimera; Diseas | 1974 |
An animal model of chronic aplastic marrow failure. I. Late marrow failure after busulfan.
Topics: Anemia, Aplastic; Animals; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Busulfan; Disease Model | 1974 |