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busulfan and Diffuse Mixed Small and Large Cell Lymphoma

busulfan has been researched along with Diffuse Mixed Small and Large Cell Lymphoma in 93 studies

Research Excerpts

ExcerptRelevanceReference
"We retrospectively evaluated early and long-term complications of an intensified conditioning regimen consisting of busulfan and etoposide in combination with either nimustine hydrochloride (ACNU) (BVA regimen, n = 18) or melphalan (BVL regimen, n = 34) in 52 children with acute leukemia or non-Hodgkin's lymphoma."7.74Long-term follow-up of busulfan, etoposide, and nimustine hydrochloride (ACNU) or melphalan as conditioning regimens for childhood acute leukemia and lymphoma. ( Fujioka, K; Funabiki, T; Goto, H; Goto, S; Hanzawa, N; Ikuta, K; Izaki, S; Kai, S; Matsuda, M; Okuda, K; Sasaki, H; Sekiguchi, H; Sumita, H; Takahashi, H; Watanabe, Y; Yokota, S, 2007)
"The combination of busulfan and cyclophosphamide has seldom been employed as a conditioning regimen for patients with lymphoma."7.69Busulfan and cyclophosphamide (BU/CY2) as preparative regimen for patients with lymphoma. ( Ball, E; de Magalhaes-Silverman, M; Lister, J; Rybka, W; Wilson, J, 1997)
"The study initially enrolled Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) patients ages 18 to 80 years but was amended due to high early treatment-related mortality (TRM) in patients > 65 years."6.82Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes. ( Ai, W; Bence-Bruckler, I; Bierman, P; Braunschweig, I; Chen, AI; Comeau, T; Costa, LJ; Craig, M; Fay, JW; Flinn, I; Flowers, CR; Freytes, CO; Horwitz, ME; Kato, K; Laneuville, P; Le-Rademacher, J; Lill, M; Mason, J; Mineishi, S; Pasquini, MC; Pulsipher, MA; Rodriguez, TE; Rondelli, D; Shea, TC; Shore, TB; Smith, AJ; Vaughan, W; Waller, EK; Wang, Y; Xu, C; Yeager, AM; Yeh, RF, 2016)
" To facilitate a therapeutic dose-monitoring protocol, we transitioned from Bu6 to daily Bu dosing for patients with Hodgkin and non-Hodgkin lymphoma undergoing autologous stem cell transplantation (ASCT)."5.43Daily Weight-Based Busulfan with Cyclophosphamide and Etoposide Produces Comparable Outcomes to Four-Times-Daily Busulfan Dosing for Lymphoma Patients Undergoing Autologous Stem Cell Transplantation. ( Andresen, S; Bolwell, BJ; Carlstrom, KD; Dean, R; Gerds, A; Hamilton, B; Hill, BT; Jagadeesh, D; Kalaycio, M; Liu, H; Majhail, NS; Pohlman, B; Rybicki, L; Sobecks, R, 2016)
" Routine dosing on the basis of BSA or AIBW in adults and adolescents does not require a specific accommodation for the obese."5.30The impact of obesity and disease on busulfan oral clearance in adults. ( Appelbaum, FR; Corneau, B; Gibbs, JP; Gooley, T; Murray, G; Slattery, JT; Stewart, P, 1999)
" Cyclosporin A and short methotrexate were used for graft-versus-host disease (GVHD) prophylaxis."5.08Combined transplantation of allogeneic bone marrow and CD34+ blood cells. ( Arseniev, L; Bähre, O; Battmer, K; Berenson, RJ; Casper, J; Diedrich, H; Jacobs, R; Kadar, JG; Kühl, J; Link, H; Poliwoda, H; Schubert, J, 1995)
"Sixteen patients with poor-prognosis acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), and non-Hodgkin's lymphoma (NHL) underwent conditioning with busulfan (16 mg/kg) and cyclophosphamide (120 mg/kg) (BUCY-2) plus melphalan (90 or 135 mg/m2) and autologous bone marrow transplantation (AuBMT) in a phase I study."5.07Busulfan, cyclophosphamide, and melphalan conditioning for autologous bone marrow transplantation in hematologic malignancy. ( Barnett, MJ; Chan, KW; Klingemann, HG; Lansdorp, PM; Nevill, TJ; Phillips, GL; Reece, DE; Shepherd, JD; Spinelli, JJ, 1991)
"We retrospectively evaluated early and long-term complications of an intensified conditioning regimen consisting of busulfan and etoposide in combination with either nimustine hydrochloride (ACNU) (BVA regimen, n = 18) or melphalan (BVL regimen, n = 34) in 52 children with acute leukemia or non-Hodgkin's lymphoma."3.74Long-term follow-up of busulfan, etoposide, and nimustine hydrochloride (ACNU) or melphalan as conditioning regimens for childhood acute leukemia and lymphoma. ( Fujioka, K; Funabiki, T; Goto, H; Goto, S; Hanzawa, N; Ikuta, K; Izaki, S; Kai, S; Matsuda, M; Okuda, K; Sasaki, H; Sekiguchi, H; Sumita, H; Takahashi, H; Watanabe, Y; Yokota, S, 2007)
"The combination of busulfan and cyclophosphamide has seldom been employed as a conditioning regimen for patients with lymphoma."3.69Busulfan and cyclophosphamide (BU/CY2) as preparative regimen for patients with lymphoma. ( Ball, E; de Magalhaes-Silverman, M; Lister, J; Rybka, W; Wilson, J, 1997)
"The study initially enrolled Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) patients ages 18 to 80 years but was amended due to high early treatment-related mortality (TRM) in patients > 65 years."2.82Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes. ( Ai, W; Bence-Bruckler, I; Bierman, P; Braunschweig, I; Chen, AI; Comeau, T; Costa, LJ; Craig, M; Fay, JW; Flinn, I; Flowers, CR; Freytes, CO; Horwitz, ME; Kato, K; Laneuville, P; Le-Rademacher, J; Lill, M; Mason, J; Mineishi, S; Pasquini, MC; Pulsipher, MA; Rodriguez, TE; Rondelli, D; Shea, TC; Shore, TB; Smith, AJ; Vaughan, W; Waller, EK; Wang, Y; Xu, C; Yeager, AM; Yeh, RF, 2016)
"One hundred two patients (Hodgkin lymphoma n = 49, non-Hodgkin lymphoma n = 12, multiple myeloma = 41) with a median age of 44 years (range: 19-65 years) were treated."2.76Intravenous busulfan plus melphalan is a highly effective, well-tolerated preparative regimen for autologous stem cell transplantation in patients with advanced lymphoid malignancies. ( Andersson, BS; Champlin, RE; Hosing, C; Jones, RB; Kazerooni, R; Kebriaei, P; Khouri, I; Ledesma, C; Madden, T; Nieto, Y; Popat, U; Qazilbash, M; Shpall, EJ; Thall, PF; Wang, X, 2011)
" In summary, the combination of treosulfan and fludarabine is a safe and efficient conditioning regimen."2.71Treosulfan and fludarabine: a new toxicity-reduced conditioning regimen for allogeneic hematopoietic stem cell transplantation. ( Casper, J; Dölken, G; Freund, M; Hammer, U; Hartung, G; Kiefer, T; Kleine, HD; Knauf, W; Knopp, A; Steiner, B; Wegener, R; Wilhelm, S; Wolff, D, 2004)
"Ten patients who relapsed are alive a median of 31 months (range, 6-47) after relapse."2.69High-dose chemotherapy with BUCY or BEAC and unpurged peripheral blood stem cell infusion in patients with low-grade non-Hodgkin's lymphoma. ( Buckner, CD; Rhinehart, S; Schwartzberg, L; Weaver, CH; West, J; West, WH; Zhen, B, 1998)
" G-CSF was given at variable dosage based on neutrophil count."2.66Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. ( Dodds, A; Fox, RM; Green, MD; Layton, JE; Lusk, J; Maher, D; Morstyn, G; Sheridan, WP; Souza, L; Wolf, M, 1989)
"The technique of high-dose chemotherapy and bone-marrow transplantation takes advantage of any potential dose-response effect in the treatment of cancer and the ability of infused marrow to circumvent severe myelotoxicity."2.38High-dose chemotherapy with busulphan and cyclophosphamide and bone-marrow transplantation for drug-sensitive malignancies in adults: a preliminary report. ( Boyd, AW; Brodie, GN; Green, MD; Griffiths, JD; McGrath, KM; Russell, DM; Scarlett, JD; Sheridan, WP; Thomas, RJ; Vaughan, SL, 1989)
" At our institution, Bu was previously administered with fixed weight-based dosing (WBD) in combination with cyclophosphamide (Cy) and etoposide (E) for patients with non-Hodgkin lymphoma (NHL) undergoing autologous stem cell transplantation (ASCT)."1.56Therapeutic Dose Monitoring of Busulfan Is Associated with Reduced Risk of Relapse in Non-Hodgkin Lymphoma Patients Undergoing Autologous Stem Cell Transplantation. ( Bolwell, B; Copelan, EA; Dean, RM; Gerds, AT; Hamilton, BK; Hill, BT; Jagadeesh, D; Kalaycio, ME; Lucena, M; Majhail, NS; Pohlman, B; Rybicki, LA; Sobecks, RM; Urban, TA, 2020)
"Lymphopenia was also a significant prognostic factor for progression-free survival (HR 3."1.43A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma. ( Cheong, JW; Cho, H; Chung, H; Jang, JE; Kim, JS; Kim, SJ; Kim, Y; Kim, YR; Lee, JY; Min, YH; Park, H, 2016)
" To facilitate a therapeutic dose-monitoring protocol, we transitioned from Bu6 to daily Bu dosing for patients with Hodgkin and non-Hodgkin lymphoma undergoing autologous stem cell transplantation (ASCT)."1.43Daily Weight-Based Busulfan with Cyclophosphamide and Etoposide Produces Comparable Outcomes to Four-Times-Daily Busulfan Dosing for Lymphoma Patients Undergoing Autologous Stem Cell Transplantation. ( Andresen, S; Bolwell, BJ; Carlstrom, KD; Dean, R; Gerds, A; Hamilton, B; Hill, BT; Jagadeesh, D; Kalaycio, M; Liu, H; Majhail, NS; Pohlman, B; Rybicki, L; Sobecks, R, 2016)
" Pharmacokinetic treatment with targeted intravenous busulfan combined with fludarabine (BuFlu) was developed as a preparative regimen for acute leukemia and myelodysplasia."1.42Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma. ( Anasetti, C; Ayala, E; Figueroa, J; Kharfan-Dabaja, MA; Kim, J; Locke, F; Nishihori, T; Perkins, J; Riches, M; Yue, B, 2015)
"IV busulfan was associated with a lower rate of relapse, and superior relapse-free survival (RFS) and OS."1.36Superior survival after replacing oral with intravenous busulfan in autologous stem cell transplantation for non-Hodgkin lymphoma with busulfan, cyclophosphamide and etoposide. ( Andresen, S; Bolwell, BJ; Copelan, EA; Curtis, J; Dean, RM; Kalaycio, ME; Pohlman, B; Rybicki, LA; Smith, SD; Sobecks, RM; Sweetenham, JW, 2010)
" After April 1999, 31 patients similar in all pretransplantation risk assessments received the same regimen except that intravenous (IV) Bu was substituted for PO Bu and pharmacokinetic-directed (PKD) dosing was attempted to achieve an area under the concentration time curve of 1000-1500 micromol/min for each dose."1.33Improved outcomes in intermediate- and high-risk aggressive non-Hodgkin lymphoma after autologous hematopoietic stem cell transplantation substituting intravenous for oral busulfan in a busulfan, cyclophosphamide, and etoposide preparative regimen. ( Aggarwal, C; Carabasi, MH; Gupta, S; Katz, RO; Nance, AG; Salzman, DE; Saylors, GB; Tilden, AB; Vaughan, WP, 2006)
"This study reports on overall and recurrence-free survival (OS and RFS) of 37 consecutive patients with low- and intermediate-grade NHL receiving a related donor allogeneic BMT using a nonradiation-containing preparative regimen."1.32Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma. ( Kiss, TL; Lipton, JH; Meharchand, J; Messner, HA; Panzarella, T; Reddy, V; Schimmer, AD, 2003)
" Routine dosing on the basis of BSA or AIBW in adults and adolescents does not require a specific accommodation for the obese."1.30The impact of obesity and disease on busulfan oral clearance in adults. ( Appelbaum, FR; Corneau, B; Gibbs, JP; Gooley, T; Murray, G; Slattery, JT; Stewart, P, 1999)
"Ten patients with non-Hodgkin's lymphoma (NHL) and nine with Hodgkin's Disease (HD) received high-dose busulfan and etoposide (VP-16) prior to autologous bone marrow transplantation (ABMT)."1.28Autologous bone marrow transplantation following high-dose busulfan and VP-16 for advanced non-Hodgkin's lymphoma and Hodgkin's disease. ( Bloom, EJ; Buck, DS; Przepiorka, D; Rosenfeld, CS; Schwinghammer, TL; Shadduck, RK, 1991)

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199019 (20.43)18.7374
1990's20 (21.51)18.2507
2000's22 (23.66)29.6817
2010's21 (22.58)24.3611
2020's11 (11.83)2.80

Authors

AuthorsStudies
Sapelli, J1
Filho, JS1
Matias Vieira, GM1
Moura, FL1
Germano, JN1
de Lima, VCC1
Kim, KH1
Lee, JH3
Lee, M1
Kim, HG1
Do, YR1
Park, Y1
Oh, SY1
Shin, HJ3
Kim, WS3
Park, SK1
Kong, JH1
Park, MR1
Yang, DH2
Kwak, JY1
Kang, HJ1
Mun, YC1
Won, JH2
Frietsch, JJ1
Miethke, J1
Linke, P1
Crodel, CC1
Schnetzke, U1
Scholl, S1
Hochhaus, A1
Hilgendorf, I1
Kaulen, LD1
Baehring, JM1
Kodama, Y1
Saburi, M1
Maruyama, R1
Sakata, M1
Takata, H1
Miyazaki, Y1
Kawano, K1
Wada, J1
Urabe, S1
Hazuku, T1
Ohtsuka, E1
Kamijo, K1
Shimomura, Y1
Shinohara, A1
Mizuno, S1
Kanaya, M1
Usui, Y1
Kim, SW2
Ara, T1
Mizuno, I1
Kuriyama, T1
Nakazawa, H1
Matsuoka, KI1
Kusumoto, S1
Maseki, N1
Yamaguchi, M1
Ashida, T1
Onizuka, M1
Fukuda, T1
Atsuta, Y1
Kondo, E1
Hill, BT2
Rybicki, LA2
Urban, TA1
Lucena, M1
Jagadeesh, D2
Gerds, AT1
Dean, RM2
Sobecks, RM2
Pohlman, B4
Bolwell, B1
Kalaycio, ME2
Hamilton, BK1
Copelan, EA5
Majhail, NS2
Kim, DY1
Chung, JS1
Jo, JC2
Cho, SH1
Kim, JS2
Lim, SN1
Lee, SM1
Yoon, SS1
Kim, IH1
Bae, SH2
Lee, YJ1
Choi, Y1
Lee, WS1
Ghosh, N1
Ahmed, S1
Ahn, KW1
Khanal, M1
Litovich, C1
Aljurf, M2
Bacher, VU1
Bredeson, C1
Epperla, N1
Farhadfar, N1
Freytes, CO2
Ganguly, S1
Haverkos, B1
Inwards, D1
Kamble, RT1
Lazarus, HM2
Lekakis, L1
Murthy, HS1
Nishihori, T2
Ramakrishnan, P1
Rizzieri, DA1
Yared, JA1
Kharfan-Dabaja, MA2
Sureda, A1
Hamadani, M1
Ji, J1
Liu, Z1
Kuang, P1
Dong, T1
Chen, X1
Li, J1
Zhang, C1
Liu, J1
Zhang, L1
Shen, K1
Liu, T1
Qualls, D1
Sullivan, A1
Li, S2
Brunner, AM1
Collier, K1
Hochberg, E2
Armand, P3
Batchelor, TT2
Chen, YB5
DeFilipp, Z1
Le Bourgeois, A1
Labopin, M1
Blaise, D2
Ceballos, P1
Vigouroux, S2
Peffault de Latour, R1
Marçais, A1
Bulabois, CE1
Bay, JO1
Chantepie, S1
Deconinck, E2
Daguindau, E1
Contentin, N1
Yakoub-Agha, I1
Cornillon, J1
Mercier, M1
Turlure, P1
Charbonnier, A1
Rorhlich, PS1
N'Guyen, S1
Maillard, N1
Marchand, T1
Mohty, M1
Chevallier, P1
Tavil, B1
Erdem, AY1
Azik, F1
Isik, P1
Metin, A1
Emir, S1
Uckan, D1
Tunc, B1
Koenigsmann, M1
Casper, J3
Kahl, C1
Basara, N1
Sayer, HG1
Behre, G1
Theurich, S1
Christopeit, M1
Mohren, M1
Reichle, A1
Metzner, B2
Ganser, A1
Stadler, M1
Uharek, L1
Balleisen, L1
Hinke, A1
Hinke, R1
Niederwieser, D1
Batchelor, T1
Brezina, M1
Jones, S1
Del Rio, C1
Curtis, M1
Ballen, KK3
Barnes, J1
Chi, AS1
Dietrich, J1
Driscoll, J1
Gertsner, ER1
Hochberg, F1
LaCasce, AS2
McAfee, SL3
Spitzer, TR3
Nayak, L1
Omuro, A1
Correa, DD1
DeAngelis, LM1
Moskowitz, CH1
Matasar, MJ1
Kaley, TJ1
Gavrilovic, IT1
Nolan, C1
Pentsova, E1
Grommes, CC1
Panageas, KS1
Baser, RE1
Faivre, G1
Abrey, LE1
Sauter, CS1
Ayala, E1
Figueroa, J1
Perkins, J1
Kim, J1
Yue, B1
Riches, M1
Locke, F1
Anasetti, C1
Lane, AA1
Logan, B1
Zhu, X1
Akpek, G1
Artz, A1
Bredeson, CN1
Cooke, KR1
Ho, VT1
Olsson, R1
Saber, W1
McCarthy, P2
Pasquini, MC2
Sakellari, I1
Mallouri, D1
Batsis, I1
Apostolou, C1
Konstantinou, V1
Abela, EM1
Douka, V1
Marvaki, A1
Karypidis, K1
Iskas, M1
Baliakas, P1
Kaloyannidis, P1
Yannaki, E1
Sotiropoulos, D1
Kouvatseas, G1
Smias, C1
Anagnostopoulos, A1
Jang, JE1
Kim, YR1
Kim, SJ3
Cho, H1
Chung, H1
Lee, JY1
Park, H1
Kim, Y1
Cheong, JW1
Min, YH1
Flowers, CR1
Costa, LJ1
Le-Rademacher, J1
Lill, M1
Shore, TB1
Vaughan, W1
Craig, M1
Shea, TC1
Horwitz, ME1
Fay, JW1
Mineishi, S1
Rondelli, D2
Mason, J1
Braunschweig, I1
Ai, W1
Yeh, RF1
Rodriguez, TE1
Flinn, I1
Comeau, T1
Yeager, AM1
Pulsipher, MA1
Bence-Bruckler, I1
Laneuville, P1
Bierman, P1
Chen, AI1
Kato, K1
Wang, Y1
Xu, C1
Smith, AJ1
Waller, EK1
Rybicki, L1
Carlstrom, KD1
Gerds, A1
Hamilton, B1
Liu, H1
Dean, R1
Sobecks, R1
Andresen, S2
Kalaycio, M2
Bolwell, BJ3
Yusuf, RZ1
Dey, B1
Yeap, BY1
McAfee, S1
Attar, E2
Sepe, PS1
Dube, C2
Zaucha, R1
Gooley, T3
Holmberg, L2
Gopal, AK1
Press, O2
Maloney, D1
Bensinger, WI2
Kerbauy, FR1
Tirapelli, B1
Akabane, H1
Oliveira, JS1
Escalón, MP1
Stefanovic, A1
Venkatraman, A1
Pereira, D1
Santos, ES1
Goodman, M1
Byrnes, JJ1
Fernandez, HF1
Lee, SC1
Lee, DH2
Suh, C3
Sweetenham, JW1
Smith, SD1
Curtis, J1
Ulrickson, M1
Aldridge, J1
Kim, HT1
Hochberg, EP2
Hammerman, P1
Dey, BR1
Grigg, AP2
Stone, J1
Milner, AD1
Schwarer, AP1
Wolf, M2
Prince, HM1
Seymour, J1
Gill, D1
Ellis, D1
Bashford, J1
Kebriaei, P1
Madden, T1
Kazerooni, R1
Wang, X1
Thall, PF1
Ledesma, C1
Nieto, Y1
Shpall, EJ1
Hosing, C1
Qazilbash, M1
Popat, U1
Khouri, I2
Champlin, RE1
Jones, RB1
Andersson, BS2
Kim, JE1
Yoo, C1
Kim, S1
Lee, JS1
Park, CJ1
Huh, J1
Andion, M1
Molina, B1
Gonzalez-Vicent, M1
Alonso, L1
Hernandez, C1
Lassaletta, A1
Lopez-Ibor, B1
Villa, M1
Diaz, MA1
Zain, J2
Palmer, JM1
Delioukina, M1
Thomas, S1
Tsai, NC1
Nademanee, A2
Popplewell, L2
Gaal, K1
Senitzer, D1
Kogut, N2
O'Donnell, M1
Forman, SJ3
Cote, GM1
Muzikansky, A1
Hochberg, FH1
Drappatz, J1
Fisher, DC1
Abramson, JS1
Campbell, P1
Friebe, A1
Foulstone, P1
Grigg, A2
Hempton, J1
Bajel, A1
Kiss, TL1
Panzarella, T1
Messner, HA1
Meharchand, J1
Reddy, V1
Schimmer, AD1
Lipton, JH2
Knauf, W1
Kiefer, T1
Wolff, D1
Steiner, B1
Hammer, U1
Wegener, R1
Kleine, HD1
Wilhelm, S1
Knopp, A1
Hartung, G1
Dölken, G1
Freund, M1
PITNEY, WR1
WEBER, RE1
HELMAN, N1
ROSSOLIMO, OK3
LEPESHKINA, GN2
PRESNOV, MA1
CHORIN, VA1
GOLDBERG, LE1
STANISLAVSKAYA, MS1
BLUMBERG, NA1
VERTOGRADOVA, TP1
ORIGENES, ML1
BEATTY, EC1
BRUBAKER, C1
HAMMOND, D1
HARTMANN, JR1
SHORE, N1
WILLIAMS, KO1
HUTCHISON, JL1
MORROW, LB1
ANDERSON, RE1
CLIFFORD, P1
BHARDWAJ, BV1
WHITTAKER, LR1
Rao, PS1
Reddy, P1
Garban, F2
Drillat, P1
Makowski, C1
Jacob, MC1
Richard, MJ1
Favrot, M1
Sotto, JJ1
Bensa, JC1
Cahn, JY1
Aggarwal, C1
Gupta, S1
Vaughan, WP1
Saylors, GB1
Salzman, DE1
Katz, RO1
Nance, AG1
Tilden, AB1
Carabasi, MH1
Rodriguez, R1
Ruel, N1
Smith, E1
Krishnan, A1
Patane, K1
Nakamura, R1
Sarkodee-Adoo, C1
Michallet, M1
Porcher, R1
Attal, M1
Ades, L1
Bernard, M1
Tabrizi, R1
Cassuto, JP1
Chevalier, P1
Facon, T1
Ifrah, N1
Renaud, M1
Tilly, H1
Vernant, JP1
Kuentz, M1
Bourhis, JH1
Bordigoni, P1
Lioure, B1
Socié, G1
Milpied, N1
Kim, JG1
Sohn, SK1
Chae, YS1
Lee, JJ1
Kim, HJ1
Jung, JS1
Kim, DH1
Eom, HS1
Izaki, S1
Goto, H1
Okuda, K1
Matsuda, M1
Watanabe, Y1
Fujioka, K1
Hanzawa, N1
Sumita, H1
Takahashi, H1
Goto, S1
Kai, S1
Sekiguchi, H1
Funabiki, T1
Sasaki, H1
Ikuta, K1
Yokota, S1
Chunduri, S1
Dobogai, LC1
Peace, D1
Saunthararajah, Y1
Quigley, J1
Chen, YH1
Mahmud, N1
Hurter, E1
Beri, R1
Rosenthal, MA1
Sheridan, WP3
Link, H1
Arseniev, L1
Bähre, O1
Berenson, RJ1
Battmer, K1
Kadar, JG1
Jacobs, R1
Kühl, J1
Schubert, J1
Diedrich, H1
Poliwoda, H1
Scheid, C1
Pettengell, R2
Ghielmini, M1
Radford, JA2
Morgenstern, GR2
Stern, PL1
Crowther, D2
van Besien, KW1
Khouri, IF1
Giralt, SA1
Mehra, R2
Przepiorka, D3
Gajewski, JL1
Bellare, N1
Nath, R1
Khalil, A1
Ciobanu, N1
Sparano, JA1
Gucalp, R1
Dutcher, JP1
Wiernik, PH1
Avalos, BR2
Klein, JL1
Kapoor, N2
Tutschka, PJ2
Klein, JP1
Scarffe, JH1
Harris, M1
Woll, PJ1
Deakin, DP1
Ryder, D1
Wilkinson, PM1
de Magalhaes-Silverman, M1
Lister, J1
Rybka, W1
Wilson, J1
Ball, E1
Al-Fiar, FZ1
Colwill, R1
Fyles, G1
Spaner, D1
Messner, H1
van Besien, K1
Thall, P1
Korbling, M1
Pugh, WC1
Giralt, S1
Anderlini, P1
Amin, K1
Mirza, N1
Seong, D1
Gajewski, J1
Hester, J1
Andersson, B1
Cabanillas, F1
Champlin, R1
Schiffman, K1
Buckner, CD2
Maziarz, R1
Maloney, DG1
Appelbaum, FR2
Lilleby, K1
Clift, R1
Zuckerman, N1
Klarnet, J1
Weaver, C1
Chauncey, T1
Weaver, CH1
Schwartzberg, L1
Rhinehart, S1
West, J1
Zhen, B1
West, WH1
Kröger, N2
Hoffknecht, M1
Hänel, M2
Krüger, W2
Zeller, W1
Stockschläder, M1
de Wit, M1
Weh, HJ1
Kabisch, H1
Erttmann, R1
Zander, AR2
Gorczyńska, E1
Toporski, J1
Bogusławska-Jaworska, J1
Słociak, M1
Gibbs, JP2
Corneau, B1
Murray, G1
Stewart, P1
Slattery, JT2
Ullery, LL1
Ames, GW1
Senecal, FM1
Nagler, A1
Slavin, S1
Varadi, G1
Naparstek, E1
Samuel, S1
Or, R1
Penza, SL1
Goormastic, M1
Andresen, SW1
Bechtel, TP1
Scholl, MD1
Elder, PJ1
Ezzone, SA1
O'Donnell, LC1
Tighe, MB1
Risley, GL1
Young, DC1
Soussain, C1
Suzan, F1
Hoang-Xuan, K1
Cassoux, N1
Levy, V1
Azar, N1
Belanger, C1
Achour, E1
Ribrag, V1
Gerber, S1
Delattre, JY1
Leblond, V1
Clarke, K1
Szer, J1
Sonnenberg, S1
Bornhäuser, M1
Kroschinsky, F1
Hänel, A1
Birkmann, J1
Schmid, B1
Hoffknecht, MM1
Fiedler, F1
Ehninger, G1
Loiseau, HA1
Hartmann, O1
Valteau, D1
McDowell, H1
Brugières, L1
Vassal, G1
Kalifa, C1
Patte, C1
Lemerle, J1
Emminger, W1
Emminger-Schmidmeier, W1
Peters, C1
Gadner, H1
Phillips, GL1
Shepherd, JD1
Barnett, MJ1
Lansdorp, PM1
Klingemann, HG1
Spinelli, JJ1
Nevill, TJ1
Chan, KW1
Reece, DE1
Rosenfeld, CS1
Schwinghammer, TL1
Buck, DS1
Bloom, EJ1
Shadduck, RK1
Gibbins, B1
Morstyn, G1
Dodds, A1
Lusk, J1
Maher, D1
Layton, JE1
Green, MD2
Souza, L1
Fox, RM1
Boyd, AW1
Russell, DM1
Thomas, RJ1
McGrath, KM1
Vaughan, SL1
Scarlett, JD1
Griffiths, JD1
Brodie, GN1
Blume, KG1
Armstrong, JG1
Van Hove, WZ1
Cohen, ML1
Weiss, EB1
Hartwich, G1
Butzler, W1
Galton, DA1
White, LP1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Chidamide Combined With Cladribine/Gemcitabine/Busulfan (ChiCGB) With Autologous Stem-Cell Transplantation in Relapsed and Refractory Diffuse Large B Cell Lymphoma[NCT03151876]Phase 293 participants (Anticipated)Interventional2017-06-12Recruiting
Phase II Trial of Hihg-Dose Thiotepa, Busulfan, Cyclophosphamide, and Rituximab With Autologous Stem Cell Transplantation for Patients With CNS Involvement by Non-Hodgkin's Lymphoma or Primary CNS Lymphoma[NCT01182415]Phase 230 participants (Actual)Interventional2010-06-30Completed
A Phase II, Single-arm Trail of Chidamide Combined With Rituximab and High-dose Methotrexate in Previously Untreated Patients With Primary Central Nervous System Lymphoma[NCT04516655]Phase 251 participants (Anticipated)Interventional2020-09-01Not yet recruiting
Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma (PCNSL)[NCT00596154]Phase 233 participants (Actual)Interventional2004-12-31Completed
A Phase II, Multicenter, Prospective, Non-randomised, Open-label, Clinical Trial to Evaluate Effectiveness and Safety of BeEAC Conditioning Regimen in Malignant Lymphoma Subjects With Indications to Autologous Hematopoietic Stem-cell Transplantation[NCT03315520]Phase 2100 participants (Anticipated)Interventional2016-01-22Recruiting
Safety and Efficacy of Ibritumomab Tiuxetan (Zevalin®) in Association With a Fludarabine Based Reduced Conditioning Regimen and Allogenic Stem Cell Support in Chemo-sensitive Relapsed CD20 Positive Aggressive Non-Hodgkin's Lymphoma Patients.[NCT00607854]Phase 231 participants (Actual)Interventional2008-02-29Completed
Safety and Efficacy of a Strategy of Allogeneic Hematopoietic Stem Cell Transplantation After Reduced-intensity Conditioning for Chemosensitive Relapsed Follicular Lymphoma[NCT01208896]Phase 232 participants (Actual)Interventional2011-02-03Completed
A Phase 2a Study of the Addition of Temozolomide to a Standard Conditioning Regimen for Autologous Stem Cell Transplantation in Relapsed and Refractory Central Nervous System (CNS) Lymphoma[NCT01235793]Phase 211 participants (Actual)Interventional2010-10-14Terminated (stopped due to The clinical trial was terminated due to poor enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

2-year Overall Survival (OS)

The percentage of participants alive after two years (NCT01182415)
Timeframe: 2 years

Interventionpercentage of participants (Number)
High-dose Chemotherapy With Autologous Stem Cell Transplant93

2-year Progression Free Survival (PFS)

The percentage of participants alive and without disease progression at 2 years. Disease progression was judged through clinical impression and MRI imaging. (NCT01182415)
Timeframe: 2 years

Interventionpercentage of participants (Number)
High-dose Chemotherapy With Autologous Stem Cell Transplant81

Proportion of Patients With CNS Involvement by B-cell NHL, Relapsed PCNSL, or Relapsed PIOL Who Are Alive and Progression-free at One Year

The proportion of patients with central nervous system (CNS) involvement by B-cell Non-Hodgkin's Lymphoma (NHL), relapsed primary central nervous system lymphoma (PCNSL), or relapsed primary intraocular lymphoma (PIOL) who are alive and progression-free at one year. Relapse was defined as per standard PCNSL criteria from clinical and MRI criteria. (NCT01182415)
Timeframe: 3 years

InterventionParticipants (Count of Participants)
High-dose Chemotherapy With Autologous Stem Cell Transplant28

Response Rate

The number of participants that achieved complete remission following high dose chemotherapy and autologous stem cell transplantation (ASCT). Complete remission is defined as the disappearance of all evidence of disease. Response was judged by MRI assessment. (NCT01182415)
Timeframe: 3 years

InterventionParticipants (Count of Participants)
High-dose Chemotherapy With Autologous Stem Cell Transplant29

Safest Dose of Temozolomide for the DRBEAT Regimen

Safety will be assessed using a dose escalation design for temozolomide's use to determine the target dose and also to evaluate any and all acute treatment related toxicities. During the course of patient follow up and therapy, toxicities will be evaluated, particularly as the investigators will be determining the target dose of temozolomide. One of the major criteria for dose limiting toxicity for the study will be any Grade 3 or 4 nonhematologic toxicity from a list of commonly expected toxicities associated with autologous transplantation and temozolomide. (NCT01235793)
Timeframe: One Year

Interventiondose in mg/m^2 (Number)
DRBEAT Regimen773.25

One-year Progression-free Survival and Overall Survival

"Efficacy of the DRBEAT Regimen will be assessed by analysis of~one-year progression-free survival (PFS), defined as the time interval from maximal response from therapy to tumor regrowth, progression*, or death, (*Progression is defined as meeting the response criteria listed in Table 4: Response Criteria for Primary Central Nervous System Lymphoma according to Abrey LE, Batchelor TT, Ferreri AJM et al.)~and~Overall survival, defined as the time interval between the date of transplant and the date of death from any cause." (NCT01235793)
Timeframe: (1) One Year (2) Until date of death from any cause, assessed up to 2 years

InterventionDays (Median)
Progression Free SurvivalOverall Survival
DRBEAT Regimen132564

Reviews

3 reviews available for busulfan and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
Treatment Options for Recurrent Primary CNS Lymphoma.
    Current treatment options in oncology, 2022, Volume: 23, Issue:11

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms

2022
High-dose chemotherapy with busulphan and cyclophosphamide and bone-marrow transplantation for drug-sensitive malignancies in adults: a preliminary report.
    The Medical journal of Australia, 1989, Oct-02, Volume: 151, Issue:7

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamid

1989
[Lactate dehydrogenase in human leukemia. A clinico-experimental study].
    Verhandelingen - Koninklijke Vlaamse Academie voor Geneeskunde van Belgie, 1972, Volume: 34, Issue:5-6

    Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Busulfan; Endotox

1972

Trials

25 trials available for busulfan and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
Busulfan, Melphalan, and Etoposide (BuME) Showed an Equivalent Effect to Busulfan, Cyclophosphamide, and Etoposide (BuCE) as Conditioning Therapy for Autologous Stem Cell Transplantation in Patients with Relapsed or High-Risk Non-Hodgkin's Lymphoma: A Mul
    Cancer research and treatment, 2023, Volume: 55, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Behavior Therapy; Busulfan; Cyclophosphamide; Etopos

2023
Phase II study of safety and efficacy of BEB (bendamustine, etoposide, and busulfan) conditioning regimen for autologous stem cell transplantation in non-Hodgkin lymphoma.
    Annals of hematology, 2020, Volume: 99, Issue:4

    Topics: Adult; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride

2020
A new conditioning regimen with chidamide, cladribine, gemcitabine and busulfan significantly improve the outcome of high-risk or relapsed/refractory non-Hodgkin's lymphomas.
    International journal of cancer, 2021, 12-15, Volume: 149, Issue:12

    Topics: Adolescent; Adult; Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzamides;

2021
Risk-adapted, treosulfan-based therapy with auto- and allo-SCT for relapsed/refractory aggressive NHL: a prospective phase-II trial.
    Bone marrow transplantation, 2014, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2014
Phase 2 trial of high-dose rituximab with high-dose cytarabine mobilization therapy and high-dose thiotepa, busulfan, and cyclophosphamide autologous stem cell transplantation in patients with central nervous system involvement by non-Hodgkin lymphoma.
    Cancer, 2015, Jan-15, Volume: 121, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols;

2015
R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.
    Blood, 2015, Feb-26, Volume: 125, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2015
R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.
    Blood, 2015, Feb-26, Volume: 125, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2015
R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.
    Blood, 2015, Feb-26, Volume: 125, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2015
R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.
    Blood, 2015, Feb-26, Volume: 125, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2015
Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:7

    Topics: Adult; Aged; Busulfan; Carmustine; Cyclophosphamide; Cytarabine; Drug Combinations; Etoposide; Hemat

2016
The effect of administration order of BU and CY on toxicity in hematopoietic SCT in humans.
    Bone marrow transplantation, 2009, Volume: 43, Issue:11

    Topics: Adolescent; Adult; Anemia, Aplastic; Busulfan; Cohort Studies; Cyclophosphamide; Follow-Up Studies;

2009
Phase II study of autologous stem cell transplant using busulfan-melphalan chemotherapy-only conditioning followed by interferon for relapsed poor prognosis follicular non-Hodgkin lymphoma.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:4

    Topics: Adult; Busulfan; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Huma

2010
Intravenous busulfan plus melphalan is a highly effective, well-tolerated preparative regimen for autologous stem cell transplantation in patients with advanced lymphoid malignancies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busu

2011
BEAM or BuCyE high-dose chemotherapy followed by autologous stem cell transplantation in non-Hodgkin's lymphoma patients: a single center comparative analysis of efficacy and toxicity.
    Leukemia research, 2011, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Cyclo

2011
Treosulfan and fludarabine: a new toxicity-reduced conditioning regimen for allogeneic hematopoietic stem cell transplantation.
    Blood, 2004, Jan-15, Volume: 103, Issue:2

    Topics: Acute Disease; Adult; Aged; Alkylating Agents; Busulfan; Chronic Disease; Family; Female; Histocompa

2004
Fludarabine/i.v. BU conditioning regimen: myeloablative, reduced intensity or both?
    Bone marrow transplantation, 2008, Volume: 41, Issue:11

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Disease-Free Survival; Drug Therapy, Combi

2008
High dose busulphan/cyclophosphamide for autologous bone marrow transplantation is associated with minimal non-hemopoietic toxicity.
    Leukemia & lymphoma, 1994, Volume: 14, Issue:3-4

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protoco

1994
Combined transplantation of allogeneic bone marrow and CD34+ blood cells.
    Blood, 1995, Oct-01, Volume: 86, Issue:7

    Topics: Adult; Antigens, CD; Antigens, CD34; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclos

1995
Pilot study of high-dose mitoxantrone and busulfan plus autologous bone transplantation in patients with advanced malignancies.
    Bone marrow transplantation, 1995, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Trans

1995
Survival benefit from high-dose therapy with autologous blood progenitor-cell transplantation in poor-prognosis non-Hodgkin's lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Busulfan; Combined Mod

1996
Allogeneic transplantation for recurrent or refractory non-Hodgkin's lymphoma with poor prognostic features after conditioning with thiotepa, busulfan, and cyclophosphamide: experience in 44 consecutive patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 1997, Volume: 3, Issue:3

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Drug Therapy,

1997
High-dose chemotherapy with BUCY or BEAC and unpurged peripheral blood stem cell infusion in patients with low-grade non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1998, Volume: 21, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Thera

1998
Autotransplantation following busulfan, etoposide and cyclophosphamide in patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2000, Volume: 25, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cyclophosphamid

2000
Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Feb-01, Volume: 19, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neoplasms; C

2001
Prolonged disease-free survival after autografting for chemosensitive non-bulky low grade non-Hodgkin's Lymphoma.
    Leukemia & lymphoma, 2000, Volume: 39, Issue:3-4

    Topics: Actuarial Analysis; Adult; Busulfan; Combined Modality Therapy; Disease-Free Survival; Female; Follo

2000
Busulfan, cyclophosphamide, and melphalan conditioning for autologous bone marrow transplantation in hematologic malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:10

    Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantati

1991
Allogeneic marrow transplantation in non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1990, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1990
Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation.
    Lancet (London, England), 1989, Oct-14, Volume: 2, Issue:8668

    Topics: Agranulocytosis; Bone Marrow Examination; Bone Marrow Transplantation; Busulfan; Clinical Trials as

1989

Other Studies

65 other studies available for busulfan and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
BuCyE can safely replace BEAM as a conditioning regimen for autologous stem cell transplantation in the treatment of refractory and relapsed lymphomas.
    Leukemia research, 2021, Volume: 110

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combi

2021
Treosulfan plus fludarabine versus TEAM as conditioning treatment before autologous stem cell transplantation for B-cell Non-Hodgkin lymphoma.
    Bone marrow transplantation, 2022, Volume: 57, Issue:7

    Topics: Aged; Busulfan; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Non-Hodgkin; Retrospectiv

2022
[Busulfan/thiotepa followed by autologous peripheral blood stem cell transplantation for refractory diffuse large B-cell lymphoma accompanied by hypopyon].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2022, Volume: 63, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Doxorubicin; Humans; Lym

2022
Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation.
    Annals of hematology, 2023, Volume: 102, Issue:3

    Topics: Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, N

2023
Therapeutic Dose Monitoring of Busulfan Is Associated with Reduced Risk of Relapse in Non-Hodgkin Lymphoma Patients Undergoing Autologous Stem Cell Transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Hematopoietic Ste

2020
Busulfan, etoposide, cytarabine, and melphalan (BuEAM) as a conditioning regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma (NHL).
    Bone marrow transplantation, 2020, Volume: 55, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cytarabine; Etoposide; Hematopoietic Stem

2020
Association of Reduced-Intensity Conditioning Regimens With Overall Survival Among Patients With Non-Hodgkin Lymphoma Undergoing Allogeneic Transplant.
    JAMA oncology, 2020, 07-01, Volume: 6, Issue:7

    Topics: Allografts; Busulfan; Cohort Studies; Cyclophosphamide; Hematopoietic Stem Cell Transplantation; Hum

2020
High-dose Thiotepa, Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplantation as Upfront Consolidation for Systemic Non-Hodgkin Lymphoma With Synchronous Central Nervous System Involvement.
    Clinical lymphoma, myeloma & leukemia, 2017, Volume: 17, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System; Combi

2017
Reduced-intensity versus reduced-toxicity myeloablative fludarabine/busulfan-based conditioning regimens for allografted non-Hodgkin lymphoma adult patients: a retrospective study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cel
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Sep-01, Volume: 28, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Female; Graft vs Host Disease

2017
Successful allogeneic hemopoietic stem cell transplantation in a case of Wiskott-Aldrich syndrome and non-Hodgkin lymphoma.
    Pediatric transplantation, 2013, Volume: 17, Issue:6

    Topics: Antilymphocyte Serum; Blood Platelets; Busulfan; Child; Hematopoietic Stem Cell Transplantation; His

2013
Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:6

    Topics: Administration, Intravenous; Adult; Aged; Antineoplastic Agents; Busulfan; Disease-Free Survival; Dr

2015
Impact of conditioning regimen on outcomes for patients with lymphoma undergoing high-dose therapy with autologous hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Busulfan; Carmustine; Cyclophosphamide; Cytarabine; Drug

2015
Carmustine, etoposide, cytarabine and melphalan versus a newly designed intravenous busulfan-based Busulfex, etoposide and melphalan conditioning regimen for autologous hematopoietic cell transplant: a retrospective matched-pair analysis in advanced Hodgk
    Leukemia & lymphoma, 2015, Volume: 56, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Cytarabine; Female; Fol

2015
A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 57

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neopla

2016
Daily Weight-Based Busulfan with Cyclophosphamide and Etoposide Produces Comparable Outcomes to Four-Times-Daily Busulfan Dosing for Lymphoma Patients Undergoing Autologous Stem Cell Transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:9

    Topics: Adult; Aged; Busulfan; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Hematopoie

2016
Autologous SCT with a dose-reduced BU and CY regimen in older patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2009, Volume: 43, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cyclophos

2009
High-dose chemotherapy with BEAM or Busulphan/Melphalan and Thiotepa followed by hematopoietic cell transplantation in malignant lymphoma.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busu

2008
Autologous transplantation for relapsed non-Hodgkin's lymphoma using intravenous busulfan and cyclophosphamide as conditioning regimen: a single center experience.
    Bone marrow transplantation, 2009, Volume: 44, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Disease Pro

2009
Excessive toxicity of once daily i.v. BU, melphalan and thiotepa followed by auto SCT on patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2010, Volume: 45, Issue:4

    Topics: Adult; Busulfan; Female; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Hu

2010
Superior survival after replacing oral with intravenous busulfan in autologous stem cell transplantation for non-Hodgkin lymphoma with busulfan, cyclophosphamide and etoposide.
    British journal of haematology, 2010, Volume: 148, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Age

2010
Busulfan and cyclophosphamide (Bu/Cy) as a preparative regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma: a single-institution experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Busulfan; Combined

2009
High-dose busulfan and cyclophosphamide as a conditioning regimen for autologous peripheral blood stem cell transplantation in childhood non-Hodgkin lymphoma patients: a long-term follow-up study.
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclo

2011
Allogeneic hematopoietic cell transplant for peripheral T-cell non-Hodgkin lymphoma results in long-term disease control.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosp

2011
Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in patients with CNS involvement by non-Hodgkin lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neopla

2012
Impact of palifermin on mucosal toxicity in autologous stem cell transplants using busulfan-melphalan conditioning chemotherapy for Hodgkin and non-Hodgkin lymphoma.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:7

    Topics: Adult; Busulfan; Drug Administration Schedule; Female; Fibroblast Growth Factor 7; Gastric Mucosa; H

2012
Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2003, Volume: 31, Issue:2

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Female; Follo

2003
Chemotherapy of malignant disease. II. Diseases of lymphoid tissue and bone marrow.
    The Medical journal of Australia, 1962, Dec-01, Volume: 49(2)

    Topics: Adrenal Cortex Hormones; Aged; Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Hodgkin Diseas

1962
THE LOCAL INFLAMMATORY RESPONSE IN PATIENTS WITH BLOOD DYSCRASIAS AS TESTED BY THE SKIN WINDOW TECHNIQUE.
    Bulletin - Sinai Hospital of Detroit, 1963, Volume: 11

    Topics: Busulfan; Hodgkin Disease; Inflammation; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte

1963
[EXPERIMENTAL STUDIES ON THE ANTITUMOR EFFECT OF OLIVOMYCIN IN ASSOCIATION WITH SOME SYNTHETIC CYTOSTATIC PREPARATIONS].
    Antibiotiki, 1963, Volume: 8

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Busulfan; Cytost

1963
HISTOLOGICAL AND HISTOCHEMICAL DATA ON THE PROCESS OF REGRESSION OF EXPERIMENTAL TUMOURS INDUCED BY ALKYLATING AGENTS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Alkaline Phosphatase; Alkylating Agents; Animals; Antineoplastic Agents; Aziridines; Busulfan; Carci

1964
EXPERIMENTAL STUDY OF OLIVOMYCIN, AN ANTITUMOUR ANTIBIOTIC.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcin

1964
TRIAL OF HYDROXYUREA (NSC-32065) IN CANCER IN CHILDREN.
    Cancer chemotherapy reports, 1964, Volume: 37

    Topics: Antineoplastic Agents; Busulfan; Child; Cyclophosphamide; Dactinomycin; Humans; Hydroxyurea; Leukemi

1964
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
    Applied therapeutics, 1964, Volume: 6

    Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Human

1964
ACTIVE TUBERCULOSIS IN LEUKEMIA. MALIGNANT LYMPHOMA AND MYELOFIBROSIS.
    Archives of pathology, 1965, Volume: 79

    Topics: Alkylating Agents; Aminopterin; Busulfan; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leu

1965
INTENSIVE NITROGEN MUSTARD THERAPY WITH ABDOMINAL AORTIC OCCLUSION IN NASOPHARYNGEAL CARCINOMA.
    British journal of cancer, 1965, Volume: 19

    Topics: Adenocarcinoma; Antineoplastic Agents; Aorta; Aorta, Abdominal; Busulfan; Carcinoma; Carcinoma, Squa

1965
Nephrotic syndrome in patients with peripheral blood stem cell transplant.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:4

    Topics: Acute Kidney Injury; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineop

2005
Extracorporeal photo-chemotherapy for graft-versus-host disease.
    Haematologica, 2005, Volume: 90, Issue:8

    Topics: Busulfan; Graft vs Host Disease; Hematologic Neoplasms; Humans; Leukemia; Lymphoma, Non-Hodgkin; Pho

2005
Extracorporeal chemophototherapy for the treatment of graft-versus-host disease: hematologic consequences of short-term, intensive courses.
    Haematologica, 2005, Volume: 90, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Busulfan; Female; Graft vs Host Disease; Hematologic

2005
Improved outcomes in intermediate- and high-risk aggressive non-Hodgkin lymphoma after autologous hematopoietic stem cell transplantation substituting intravenous for oral busulfan in a busulfan, cyclophosphamide, and etoposide preparative regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Busulfan; Chi-Square Distribution; Cyclophosphamide;

2006
Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Busulfan; Cause of Death; Cohort Studies; Cyclophosphamide; Disease-Free Su

2006
Long-term outcomes after reduced-intensity conditioning allogeneic stem cell transplantation for low-grade lymphoma: a survey by the French Society of Bone Marrow Graft Transplantation and Cellular Therapy (SFGM-TC).
    Haematologica, 2007, Volume: 92, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Prot

2007
Multicenter study of intravenous busulfan, cyclophosphamide, and etoposide (i.v. Bu/Cy/E) as conditioning regimen for autologous stem cell transplantation in patients with non-Hodgkin's lymphoma.
    Bone marrow transplantation, 2007, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Etopo

2007
Long-term follow-up of busulfan, etoposide, and nimustine hydrochloride (ACNU) or melphalan as conditioning regimens for childhood acute leukemia and lymphoma.
    International journal of hematology, 2007, Volume: 86, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; C

2007
Time-course of the recovery of cellular immune function after high-dose chemotherapy and peripheral blood progenitor cell transplantation for high-grade non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases;

1995
Allogeneic bone marrow transplantation for refractory and recurrent low-grade lymphoma: the case for aggressive management.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cispla

1995
Preparation for marrow transplantation in Hodgkin's and non-Hodgkin's lymphoma using Bu/CY.
    Bone marrow transplantation, 1993, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Thera

1993
Busulfan and cyclophosphamide (BU/CY2) as preparative regimen for patients with lymphoma.
    Bone marrow transplantation, 1997, Volume: 19, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan;

1997
Abnormal thyroid stimulating hormone (TSH) levels in adults following allogeneic bone marrow transplants.
    Bone marrow transplantation, 1997, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Dise

1997
High-dose busulfan, melphalan, and thiotepa followed by autologous peripheral blood stem cell transplantation in patients with aggressive lymphoma or relapsed Hodgkin's disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 1997, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality

1997
Busulfan, cyclophosphamide and etoposide as high-dose conditioning therapy in patients with malignant lymphoma and prior dose-limiting radiation therapy.
    Bone marrow transplantation, 1998, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu

1998
High-dose chemotherapy with autologous hematopoietic progenitor cell transplantation in children with high-risk NHL and ALL-preliminary results.
    Bone marrow transplantation, 1998, Volume: 22 Suppl 4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclo

1998
The impact of obesity and disease on busulfan oral clearance in adults.
    Blood, 1999, Jun-15, Volume: 93, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Body Mass Index; Body Surface Area; Body Weight; Busulfan;

1999
Busulfan clearance in renal failure and hemodialysis.
    Bone marrow transplantation, 2000, Volume: 25, Issue:2

    Topics: Administration, Oral; Biological Availability; Blood Transfusion, Autologous; Busulfan; Hematopoieti

2000
Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma.
    Bone marrow transplantation, 2000, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Antilymphocyte Serum; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2000
Busulfan, cyclophosphamide, and etoposide as high-dose conditioning regimen in patients with malignant lymphoma.
    Annals of hematology, 2002, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Thera

2002
High-dose chemotherapy containing busulfan followed by bone marrow transplantation in 24 children with refractory or relapsed non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1991, Volume: 8, Issue:6

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Dose-Res

1991
Influence of immunosuppression on acute liver toxicity after intensified conditioning regimens for bone marrow transplantation in children.
    Blood, 1991, Apr-01, Volume: 77, Issue:7

    Topics: Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Drug Therapy, Combination; Etoposide; Gr

1991
Autologous bone marrow transplantation following high-dose busulfan and VP-16 for advanced non-Hodgkin's lymphoma and Hodgkin's disease.
    Experimental hematology, 1991, Volume: 19, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow

1991
High dose busulfan/etoposide as a preparatory regimen for second bone marrow transplants in hematologic malignancies.
    Blut, 1987, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Bone Marrow Tr

1987
Current problems in the use of the oncolytic drugs.
    Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac

1968
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
    Chest, 1971, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam

1971
[Experimental study of antitumor action of rubomycin in combination with some cytostatic compounds].
    Antibiotiki, 1967, Volume: 12, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Drug Synergism; Lymphoma, Non

1967
[Secondary tumors in hemoblastoses during cytostatic treatment].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo

1971
Some problems in the management of leukaemia and lymphoma.
    Proceedings of the Royal Society of Medicine, 1966, Volume: 59, Issue:12

    Topics: Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Humans; Leukemia; Leukemia, Lymphoid; Leu

1966
Leukemia and lymphoma.
    Geriatrics, 1970, Volume: 25, Issue:12

    Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cyta

1970