Page last updated: 2024-10-24

busulfan and Cystitis

busulfan has been researched along with Cystitis in 33 studies

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"Between October 1988 and December 1992, 167 patients with leukemia receiving marrow transplants from HLA-identical donors and conditioned with cyclophosphamide (120 mg/kg) were randomized to additional treatment with either busulfan (16 mg/kg, n = 88) or total body irradiation (TBI; n = 79)."9.07A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group. ( Lenhoff, S; Ljungman, P; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1994)
"High dose cyclophosphamide and/or busulfan conditioning treatment of recipients of bone marrow transplants proved to be highly effective but associated with substantial and sometimes life threatening hemorrhagic cystitis."7.69Prevention of hemorrhagic cystitis following allogeneic bone marrow transplant preparative regimens with cyclophosphamide and busulfan: role of continuous bladder irrigation. ( Abella, E; Haas, GP; Karanes, C; Lum, LG; Momin, F; Sensenbrenner, LL; Turkeri, LN; Uberti, JP, 1995)
"We report a case of severe hemorrhagic cystitis induced by prolonged busulfan therapy."7.66Busulfan-induced hemorrhagic cystitis. ( Perlberg, S; Pode, D; Steiner, D, 1983)
"A case of a busulfan-induced hemorrhage cystitis is reported."7.66Busulfan-induced hemorrhagic cystitis. ( Millard, RJ, 1981)
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."6.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
"Between October 1988 and December 1992, 167 patients with leukemia receiving marrow transplants from HLA-identical donors and conditioned with cyclophosphamide (120 mg/kg) were randomized to additional treatment with either busulfan (16 mg/kg, n = 88) or total body irradiation (TBI; n = 79)."5.07A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group. ( Lenhoff, S; Ljungman, P; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1994)
"High dose cyclophosphamide and/or busulfan conditioning treatment of recipients of bone marrow transplants proved to be highly effective but associated with substantial and sometimes life threatening hemorrhagic cystitis."3.69Prevention of hemorrhagic cystitis following allogeneic bone marrow transplant preparative regimens with cyclophosphamide and busulfan: role of continuous bladder irrigation. ( Abella, E; Haas, GP; Karanes, C; Lum, LG; Momin, F; Sensenbrenner, LL; Turkeri, LN; Uberti, JP, 1995)
"We report a case of severe hemorrhagic cystitis induced by prolonged busulfan therapy."3.66Busulfan-induced hemorrhagic cystitis. ( Perlberg, S; Pode, D; Steiner, D, 1983)
"A case of a busulfan-induced hemorrhage cystitis is reported."3.66Busulfan-induced hemorrhagic cystitis. ( Millard, RJ, 1981)
"Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =."2.69Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta ( Jacobsen, N; Lenhoff, S; Ljungman, P; Mellander, L; Nikoskelainen, J; Parkkali, T; Remberger, M; Ringdén, O; Ruutu, T; Sallerfors, B; Vindeløv, L; Volin, L, 1999)
"To evaluate the toxic extramedullary morbidity of the conditioning treatment with BuCy for BMT, as well as the usefulness of pentoxyphyllin (PTX) and methylprednisolone (MP) in the prophylaxis of mucositis."2.39[Extramedullary toxicity in bone marrow transplantation using busulfan and cyclophosphamide conditioning]. ( Maldonado, J; Pascual, MJ, 1995)
"Mesna possibly has a toxic effect on bladder mucosa."1.32Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation. ( Hattori, K; Hotta, T; Inoue, H; Kato, S; Kawada, H; Kishi, K; Matsumoto, M; Ogawa, Y; Ohmachi, K; Shimizu, T; Tsuboi, K; Watanabe, S; Yabe, H; Yabe, M; Yasuda, Y; Yoshiba, F, 2003)
"Haemorrhagic cystitis is a common and often debilitating complication of chemotherapy for which treatment is frequently unsatisfactory."1.30Hyperbaric oxygen in the treatment of refractory haemorrhagic cystitis. ( Hughes, AJ; Millar, IL; Schwarer, AP, 1998)
" Thus, we have developed a safe chemotherapy schedule for transplantation that avoids the need for radiotherapy and can, if necessary, be repeated after a 3-month interval."1.27Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children. ( Barnes, R; Downie, CJ; Hobbs, JR; Hugh-Jones, K; Shaw, PJ, 1986)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19906 (18.18)18.7374
1990's14 (42.42)18.2507
2000's7 (21.21)29.6817
2010's5 (15.15)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Santos Carreira, A1
Salas, MQ1
Remberger, M4
Novitzky-Basso, I1
Law, AD1
Lam, W2
Pasic, I1
Mazzulli, T1
Cserti-Gazdewich, C1
Kim, DDH1
Michelis, FV2
Viswabandya, A1
Gerbitz, A1
Lipton, JH2
Kumar, R1
Hassan, M2
Mattsson, J2
Törlen, J1
Serafi, IE1
Garming-Legert, K1
Björklund, A1
Ljungman, P3
Sundin, M1
Wang, J1
Zhao, J1
Fei, X1
Yin, Y1
Cheng, H1
Zhang, W1
Gu, J1
Yang, F1
Yang, Y1
Xue, S1
Tian, Z1
He, J1
Zhang, S1
Wang, X1
Uhm, J1
Hamad, N1
Shanavas, M1
Kuruvilla, J1
Gupta, V1
Messner, HA1
Seftel, M1
Kim, DD1
Storek, J1
Li, H1
Geddes, M1
Daly, A1
Gruhn, B1
Klöppner, N1
Pfaffendorf-Regler, N1
Beck, J1
Zintl, F1
Bartholomä, S1
Debatin, KM1
Steinbach, D1
Tsuboi, K1
Kishi, K1
Ohmachi, K1
Yasuda, Y1
Shimizu, T1
Inoue, H1
Matsumoto, M1
Hattori, K1
Yoshiba, F1
Watanabe, S1
Ogawa, Y1
Kawada, H1
Yabe, H1
Yabe, M1
Kato, S1
Hotta, T1
Yamamoto, R1
Kusumi, E1
Kami, M1
Yuji, K1
Hamaki, T1
Saito, A1
Murasgihe, N1
Hori, A1
Kim, SW1
Makimoto, A1
Ueyama, J1
Tanosaki, R1
Miyakoshi, S1
Mori, S1
Morinaga, S1
Heike, Y1
Taniguchi, S1
Masuo, S1
Takaue, Y1
Mutou, Y1
Asano, Y1
Kanda, Y1
Ogawa, N1
Sakata-Yanagimoto, M1
Nakagawa, M1
Kawazu, M1
Goyama, S1
Kandabashi, K1
Izutsu, K1
Imai, Y1
Hangaishi, A1
Kurokawa, M1
Tsujino, S1
Ogawa, S1
Aoki, K1
Chiba, S1
Motokura, T1
Hirai, H1
Pode, D1
Perlberg, S1
Steiner, D1
Millard, RJ2
Pascual, MJ1
Maldonado, J1
Klingemann, HG1
Shepherd, JD1
Reece, DE1
Barnett, MJ1
Nantel, SH1
Sutherland, HJ1
Spinelli, JJ1
Phillips, GL1
Turkeri, LN1
Lum, LG1
Uberti, JP1
Abella, E1
Momin, F1
Karanes, C1
Sensenbrenner, LL1
Haas, GP1
Ringdén, O2
Ruutu, T2
Nikoskelainen, J2
Volin, L2
Vindeløv, L2
Parkkali, T2
Lenhoff, S2
Sallerfors, B2
Bernaudin, F1
Souillet, G1
Vannier, JP1
Plouvier, E1
Lemerle, S1
Michel, G1
Bordigoni, P1
Lutz, P1
Kuentz, M1
Erer, B1
Angelucci, E1
Baronciani, D1
Tomasucci, M1
Giardini, C1
Gaziev, J1
Hughes, AJ1
Schwarer, AP1
Millar, IL1
Kondo, M1
Kojima, S1
Kato, K1
Matsuyama, T1
Mellander, L1
Jacobsen, N1
Peinemann, F1
de Villiers, EM1
Dörries, K1
Adams, O1
Vögeli, TA1
Burdach, S1
Ikegame, K1
Takimoto, T1
Takahashi, R1
Murakami, M1
Tamaki, H1
Fujioka, T1
Kawakami, M1
Hirabayashi, N1
Soma, T1
Sugiyama, H1
Ogawa, H1
Zhu, K1
Xu, Y1
Wu, D1
Xu, X1
Huang, L1
Leung, AY1
Mak, R1
Lie, AK1
Yuen, KY1
Cheng, VC1
Liang, R1
Kwong, YL1
Kasai, M1
Kiyama, Y1
Watanabe, M1
Seto, K1
Matsuura, A1
Tanaka, J1
Takeda, H1
Naohara, T1
Higa, T1
Hashino, S1
Flowers, ME1
Doney, KC1
Storb, R1
Deeg, HJ1
Sanders, JE1
Sullivan, KM1
Bryant, E1
Witherspoon, RP1
Appelbaum, FR1
Buckner, CD1
Romeiras, M1
Rodrigues, AS1
Machado, A1
Jorge, L1
Nolasco, I1
Abecasis, M1
Morgan, M1
Dodds, A3
Atkinson, K3
Szer, J1
Downs, K2
Biggs, J2
Biggs, JC1
Golovsky, D1
Concannon, A2
Ashby, M2
Thomas, AE1
Patterson, J1
Prentice, HG1
Brenner, MK1
Ganczakowski, M1
Hancock, JF1
Pattinson, JK1
Blacklock, HA1
Hopewell, JP1
Shaw, PJ1
Hugh-Jones, K1
Hobbs, JR1
Downie, CJ1
Barnes, R1
Noble, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Chronic Phase CML[NCT00001144]Phase 250 participants Interventional1999-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for busulfan and Cystitis

ArticleYear
Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:12

    Topics: Adenoviridae Infections; Adenoviruses, Human; Adolescent; Adult; Aged; Anemia, Aplastic; BK Virus; B

2003
[Extramedullary toxicity in bone marrow transplantation using busulfan and cyclophosphamide conditioning].
    Sangre, 1995, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Anemia, Refractory, with Excess of Blasts; Arrhythmias, Cardiac; Bone Marrow Tran

1995
Regimen-related acute toxicities: pathophysiology, risk factors, clinical evaluation and preventive strategies.
    Bone marrow transplantation, 1994, Volume: 14 Suppl 4

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Tr

1994

Trials

4 trials available for busulfan and Cystitis

ArticleYear
A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group.
    Blood, 1994, May-01, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Cause of Death; Child; Child, Preschool; C

1994
Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplanta
    Blood, 1999, Apr-01, Volume: 93, Issue:7

    Topics: Adolescent; Adult; Alopecia; Bone Marrow Transplantation; Bronchiolitis Obliterans; Busulfan; Catara

1999
Relative toxicity of two different conditioning regimens in patients undergoing allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 2

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1991
Bladder irrigation does not prevent haemorrhagic cystitis in bone marrow transplant recipients.
    Bone marrow transplantation, 1991, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Catheters, Indwelling; Cyclophosphamide; C

1991

Other Studies

26 other studies available for busulfan and Cystitis

ArticleYear
Interaction Between High-Dose Intravenous Busulfan and Post-Transplantation Cyclophosphamide on Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplantation.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:9

    Topics: Adult; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Cyclosporine; Cystitis; Hematopoietic Stem

2023
Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation.
    International journal of hematology, 2017, Volume: 106, Issue:4

    Topics: Adolescent; Adult; Aged; Allografts; Busulfan; Child; Child, Preschool; Cystitis; Female; Hematopoie

2017
A new intensive conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with refractory or relapsed acute myeloid leukemia.
    Medicine, 2018, Volume: 97, Issue:17

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Cystitis; Cytarabine; Cytomegalovirus Infections; Dru

2018
The risk of polyomavirus BK-associated hemorrhagic cystitis after allogeneic hematopoietic SCT is associated with myeloablative conditioning, CMV viremia and severe acute GVHD.
    Bone marrow transplantation, 2014, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Aged; BK Virus; Busulfan; Cystitis; Cytomegalovirus Infections; Female; Graft vs

2014
Incidence and risk factor of hemorrhagic cystitis after allogeneic transplantation with fludarabine, busulfan, and anti-thymocyte globulin myeloablative conditioning.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:3

    Topics: Antilymphocyte Serum; BK Virus; Busulfan; Case-Control Studies; Cystitis; Disease-Free Survival; Dru

2017
Toll-like 4 receptor variant, Asp299Gly, and reduced risk of hemorrhagic cystitis after hematopoietic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Busulfan; Child; Child, Preschool; Cystitis;

2012
Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:9

    Topics: Adolescent; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Cystitis; Drug Synergism; Female; Hema

2003
Late hemorrhagic cystitis after reduced-intensity hematopoietic stem cell transplantation (RIST).
    Bone marrow transplantation, 2003, Volume: 32, Issue:11

    Topics: Adenoviridae; Adolescent; Adult; Aged; Antibodies, Viral; Busulfan; Child; Child, Preschool; Cystiti

2003
Busulfan-induced hemorrhagic cystitis.
    The Journal of urology, 1983, Volume: 130, Issue:2

    Topics: Adult; Busulfan; Cystitis; Female; Hemorrhage; Humans; Leukemia, Myeloid; Time Factors; Urinary Blad

1983
Busulfan-induced hemorrhagic cystitis.
    Urology, 1981, Volume: 18, Issue:2

    Topics: Busulfan; Cystitis; Hemorrhage; Humans; Male; Middle Aged; Urinary Bladder Diseases

1981
Prevention of hemorrhagic cystitis following allogeneic bone marrow transplant preparative regimens with cyclophosphamide and busulfan: role of continuous bladder irrigation.
    The Journal of urology, 1995, Volume: 153, Issue:3 Pt 1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cystitis; Female; Hemorr

1995
Bone marrow transplantation (BMT) in 14 children with severe sickle cell disease (SCD): the French experience. GEGMO.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Adolescent; Africa; Anemia, Sickle Cell; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan;

1993
Hemorrhagic cystitis after allogeneic bone marrow transplantation for thalassemia.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Adolescent; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Child; Child, Prescho

1993
Hyperbaric oxygen in the treatment of refractory haemorrhagic cystitis.
    Bone marrow transplantation, 1998, Volume: 22, Issue:6

    Topics: Adenoviruses, Human; Adult; Antineoplastic Agents, Alkylating; BK Virus; Busulfan; Cyclophosphamide;

1998
Late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation in children.
    Bone marrow transplantation, 1998, Volume: 22, Issue:10

    Topics: Adolescent; Age Factors; Antilymphocyte Serum; Busulfan; Child; Child, Preschool; Cyclosporine; Cyst

1998
Clinical course and treatment of haemorrhagic cystitis associated with BK type of human polyomavirus in nine paediatric recipients of allogeneic bone marrow transplants.
    European journal of pediatrics, 2000, Volume: 159, Issue:3

    Topics: Adolescent; BK Virus; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cystitis; Fema

2000
Lethal adenovirus infection in a patient who had undergone nonmyeloablative stem cell transplantation.
    International journal of hematology, 2001, Volume: 74, Issue:1

    Topics: Adenoviridae Infections; Adenoviruses, Human; Antilymphocyte Serum; Bronchoalveolar Lavage Fluid; Bu

2001
[The toxicity of busulphan and cyclophosphamide as the preparative regimen for allogeneic peripheral blood stem cell transplantation].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2000, Volume: 21, Issue:8

    Topics: Acute Disease; Adult; Busulfan; Cyclophosphamide; Cystitis; Disease-Free Survival; Esophagitis; Fema

2000
Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation.
    Bone marrow transplantation, 2002, Volume: 29, Issue:6

    Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Aged; BK Virus; Bone Marrow Transplantatio

2002
Busulphan haemorrhagic cystitis.
    British journal of urology, 1978, Volume: 50, Issue:3

    Topics: Busulfan; Cystitis; Hematuria; Humans; Leukemia, Myeloid; Male; Middle Aged

1978
Toxicity of high-dose busulfan and cyclophosphamide as a preparative regimen for bone marrow transplantation.
    Transplantation proceedings, 1992, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cystitis; Dose-Response

1992
Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience.
    Bone marrow transplantation, 1992, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1992
The toxicity of busulphan and cyclophosphamide as the preparative regimen for bone marrow transplantation.
    British journal of haematology, 1991, Volume: 77, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cystitis; Drug Therapy,

1991
Haemorrhagic cystitis in bone marrow transplantation patients: possible increased risk associated with prior busulphan therapy.
    Bone marrow transplantation, 1987, Volume: 1, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide;

1987
Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children.
    Bone marrow transplantation, 1986, Volume: 1, Issue:2

    Topics: Adolescent; Bone Marrow; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosph

1986
Preparative regimens for marrow transplantation containing busulphan are associated with haemorrhagic cystitis and hepatic veno-occlusive disease but a short duration of leucopenia and little oro-pharyngeal mucositis.
    Bone marrow transplantation, 1987, Volume: 2, Issue:4

    Topics: Anemia, Aplastic; Bone Marrow Transplantation; Busulfan; Cystitis; Hemorrhage; Hepatic Veno-Occlusiv

1987