busulfan has been researched along with Blast Phase in 31 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "An attempt to prevent the blast crisis in chronic myeloid leukemia by the use of pulsed doses of (cytarabine cytosine arabinoside) and lomustine was attempted as a cooperative group study by Cancer and Leukemia Group B." | 9.07 | Attempted prevention of blast crisis in chronic myeloid leukemia by the use of pulsed doses of cytarabine and lomustine. A Cancer and Leukemia Group B study. ( Brunner, K; Dear, KB; Haurani, F; Holland, JF; Karanas, A; Silver, RT; Weil, M, 1992) |
| "The frequency of induced sister chromatid exchange (SCE) as a sensitive parameter for chemotherapy resistance was studied after in vitro treatment with busulfan in four cases of myeloid blast crisis of Philadelphia chromosome (Ph)-positive chronic myeloid leukemia (CML)." | 7.68 | Biclonal analysis of busulfan-induced sister chromatid exchange in blast crisis of Philadelphia chromosome-positive chronic myeloid leukemia. ( Becher, R; Prescher, G, 1991) |
| "Thirty-six adults with chronic myelogenous leukemia (CML) in second or greater chronic phase, accelerated phase, or blast crisis underwent marrow or blood stem cell transplantation from an HLA-matched sibling using high-dose thiotepa, busulfan and cyclophosphamide (TBC) as the preparative regimen." | 5.09 | Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia. ( Andersson, B; Champlin, R; Deisseroth, AB; Gajewski, J; Giralt, S; Ippoliti, C; Khouri, I; Körbling, M; Lee, MS; Mehra, R; Przepiorka, D; Thall, P; van Besien, K, 1999) |
| "A national cooperative group trial was conducted in 153 patients with chronic myelogenous leukemia (CML) in chronic phase treated with oral pulse busulfan to determine if oral vitamin A can increase the time to blast crisis and enhance survival of patients." | 5.08 | Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial. ( Appelbaum, FR; Balcerzak, SP; Hynes, H; Kopecky, KJ; Meyskens, FL; Samlowski, W, 1995) |
| "Six patients with either acceleration or blast crisis of transformed chronic myeloid leukemia (CML) were treated with high-dose interferon alpha in combination with hydroxyurea." | 5.08 | Successful treatment of accelerated and blastic phase of chronic myeloid leukemia with high-dose interferon alpha and hydroxyurea: a novel approach. ( Heinemann, V; Jehn, U; Pötscher, C, 1995) |
| "An attempt to prevent the blast crisis in chronic myeloid leukemia by the use of pulsed doses of (cytarabine cytosine arabinoside) and lomustine was attempted as a cooperative group study by Cancer and Leukemia Group B." | 5.07 | Attempted prevention of blast crisis in chronic myeloid leukemia by the use of pulsed doses of cytarabine and lomustine. A Cancer and Leukemia Group B study. ( Brunner, K; Dear, KB; Haurani, F; Holland, JF; Karanas, A; Silver, RT; Weil, M, 1992) |
| "A 57-year-old male who had suffered from polycythemia vera (PV) and had been treated with pipobroman, carbazilquinon and busulfan for ten years presented with fever." | 4.78 | [Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. ( Hino, K; Koike, T; Sakashita, A; Sato, S; Tomoyasu, S; Tsuruoka, N, 1992) |
| " All the patients were conditioned with cyclophosphamide and busulfan, and treated with cyclosporin (CsA)/methotrexate (MTX)/mycophenolate mofetil (MMF) for graft-versus-host disease (GVHD) prophylaxis." | 3.77 | Imatinib combined with myeloablative allogeneic hematopoietic stem cell transplantation for advanced phases of chronic myeloid leukemia. ( Cai, Z; Han, X; He, J; Huang, H; Li, L; Lin, M; Luo, Y; Shi, J; Tan, Y; Xie, W; Ye, X; Zhao, Y; Zheng, Y, 2011) |
| " Overexpression of P-170 without amplification of MDR-1 was found in four of 11 patients with chronic phase CML at diagnosis, seven of 16 patients treated with busulfan or hydroxyurea in chronic phase and four of 15 patients in blast crisis." | 3.68 | The role of the MDR-1/P-170 mechanism in the development of multidrug resistance in chronic myeloid leukemia. ( Dowding, C; Goldman, J; Paulsen, W; Weide, R, 1990) |
| "The frequency of induced sister chromatid exchange (SCE) as a sensitive parameter for chemotherapy resistance was studied after in vitro treatment with busulfan in four cases of myeloid blast crisis of Philadelphia chromosome (Ph)-positive chronic myeloid leukemia (CML)." | 3.68 | Biclonal analysis of busulfan-induced sister chromatid exchange in blast crisis of Philadelphia chromosome-positive chronic myeloid leukemia. ( Becher, R; Prescher, G, 1991) |
| "The clinical course of 196 patients with chronic myelocytic leukemia (CML) was studied." | 2.67 | [Evaluation of 196 patients with chronic myeloid leukemia based on a standard prognosis model]. ( Anger, B; Carbonell, F; Ganser, A; Heimpel, H; Robertson, J; Schmeiser, T; Sokal, JE, 1990) |
| "Splenomegaly and hepatomegaly were present in 90% and 48% respectively." | 1.28 | Chronic granulocytic leukaemia. A study of 160 cases. ( Kumar, L; Maitreyan, V; Majhi, U; Sagar, TG; Shanta, V, 1990) |
| "A case of chronic myelogenous leukemia (CML) of 10-year survival in described." | 1.28 | [Bone marrow aplasia without blast crisis in a case of CML of 10-year survival]. ( Abe, R; Ishibashi, T; Kariyone, S; Kimura, H; Matsuda, S; Shichishima, T; Shiga, Y; Uchida, T; Yokoyama, A; Yui, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 18 (58.06) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JH | 1 |
| Stein, A | 1 |
| Tsai, N | 1 |
| Schultheiss, TE | 1 |
| Palmer, J | 1 |
| Liu, A | 1 |
| Rosenthal, J | 1 |
| Forman, SJ | 1 |
| Wong, JY | 1 |
| Luo, Y | 1 |
| Zhao, Y | 1 |
| Tan, Y | 1 |
| Shi, J | 1 |
| Han, X | 1 |
| Zheng, Y | 1 |
| Li, L | 1 |
| He, J | 1 |
| Xie, W | 1 |
| Ye, X | 1 |
| Cai, Z | 1 |
| Lin, M | 1 |
| Huang, H | 1 |
| Oyekunle, AA | 1 |
| Kröger, N | 1 |
| Zabelina, T | 1 |
| Ayuk, F | 1 |
| Schieder, H | 1 |
| Renges, H | 1 |
| Fehse, N | 1 |
| Waschke, O | 1 |
| Fehse, B | 1 |
| Kabisch, H | 1 |
| Zander, AR | 1 |
| Busuttil, DP | 1 |
| Meyskens, FL | 1 |
| Kopecky, KJ | 1 |
| Appelbaum, FR | 1 |
| Balcerzak, SP | 1 |
| Samlowski, W | 1 |
| Hynes, H | 1 |
| Kiyoi, H | 1 |
| Fukutani, H | 1 |
| Yamauchi, T | 1 |
| Kubo, K | 1 |
| Ohno, R | 1 |
| Yamamori, S | 1 |
| Naoe, T | 1 |
| Hehlmann, R | 2 |
| Heimpel, H | 3 |
| Hasford, J | 2 |
| Kolb, HJ | 2 |
| Pralle, H | 2 |
| Hossfeld, DK | 2 |
| Queisser, W | 2 |
| Löffler, H | 2 |
| Hochhaus, A | 1 |
| Heinze, B | 2 |
| Goldman, JM | 2 |
| Shibata, A | 1 |
| Reiffers, J | 1 |
| Montastruc, M | 1 |
| Marit, G | 1 |
| Cony-Makhoul, P | 1 |
| Faberes, C | 1 |
| Bilhou-Nabera, C | 1 |
| Gharbi, MJ | 1 |
| Bernard, P | 1 |
| Vezon, G | 1 |
| Broustet, A | 1 |
| Georgii, A | 1 |
| Grande, M | 1 |
| Jehn, U | 1 |
| Pötscher, C | 1 |
| Heinemann, V | 1 |
| Manley, R | 1 |
| Cochrane, J | 1 |
| McDonald, M | 1 |
| Rigby, S | 1 |
| Moore, A | 1 |
| Kirk, A | 1 |
| Clarke, S | 1 |
| Crossen, PE | 1 |
| Morris, CM | 1 |
| Patton, WN | 1 |
| Przepiorka, D | 1 |
| Khouri, I | 1 |
| Thall, P | 1 |
| Mehra, R | 1 |
| Lee, MS | 1 |
| Ippoliti, C | 1 |
| Giralt, S | 1 |
| Gajewski, J | 1 |
| van Besien, K | 1 |
| Andersson, B | 1 |
| Körbling, M | 1 |
| Deisseroth, AB | 1 |
| Champlin, R | 1 |
| Takami, A | 1 |
| Chuhjo, T | 1 |
| Nakao, S | 1 |
| Silver, RT | 2 |
| Karanas, A | 1 |
| Dear, KB | 1 |
| Weil, M | 1 |
| Brunner, K | 1 |
| Haurani, F | 1 |
| Holland, JF | 2 |
| Glejzer, O | 1 |
| Sedzimirska, M | 1 |
| Tomaszewska-Toporska, B | 1 |
| Tomeczko, J | 1 |
| Kołodziej, J | 1 |
| Pacuszko, T | 1 |
| Was, A | 1 |
| Bocheńska, J | 1 |
| Jaźwiec, B | 1 |
| Klimczak, A | 1 |
| Hino, K | 1 |
| Sato, S | 1 |
| Sakashita, A | 1 |
| Tomoyasu, S | 1 |
| Tsuruoka, N | 1 |
| Koike, T | 1 |
| Anger, B | 1 |
| Schmeiser, T | 1 |
| Robertson, J | 1 |
| Sokal, JE | 1 |
| Ganser, A | 1 |
| Carbonell, F | 1 |
| Weide, R | 1 |
| Dowding, C | 1 |
| Paulsen, W | 1 |
| Goldman, J | 1 |
| Becher, R | 1 |
| Prescher, G | 1 |
| Kumar, L | 1 |
| Sagar, TG | 1 |
| Maitreyan, V | 1 |
| Majhi, U | 1 |
| Shanta, V | 1 |
| Kotelnikov, VM | 1 |
| Lishmanova, NG | 1 |
| Khoroshko, ND | 1 |
| Alieva, TM | 1 |
| Kozinets, GI | 1 |
| Allan, NC | 2 |
| Shepherd, PC | 1 |
| Shiga, Y | 1 |
| Yokoyama, A | 1 |
| Ishibashi, T | 1 |
| Shichishima, T | 1 |
| Abe, R | 1 |
| Yui, T | 1 |
| Kimura, H | 1 |
| Matsuda, S | 1 |
| Uchida, T | 1 |
| Kariyone, S | 1 |
| Mick, R | 1 |
| Degnan, TJ | 1 |
| Cavelli, F | 1 |
| Avilés, A | 1 |
| Ibarrola, JL | 1 |
| Sigler, L | 1 |
| Pizzuto, J | 1 |
| Inoue, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Pegylated Proline Interferon Alpha 2b (AOP2014) in Maintaining Deep Molecular Remissions in Patients With Chronic Myeloid Leukemia (CML) Who Discontinue ABL-Kinase Inhibitor Therapy - a Randomized Phase III, Multicenter Trial With P[NCT03117816] | Phase 3 | 214 participants (Actual) | Interventional | 2017-05-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for busulfan and Blast Phase
| Article | Year |
|---|---|
Management of chronic myeloid leukaemia.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Blast Crisis; Bone Marrow Transplantation; Busulfan; Ch | 1994 |
[Allogeneic bone marrow transplantation in myeloid leukemia: chemical conditioning, clinical course and results].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transpl | 1992 |
[Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report].
Topics: Blast Crisis; Busulfan; Carbazilquinone; Disseminated Intravascular Coagulation; Humans; Leukemia, M | 1992 |
Treatment of chronic myeloid leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Busulfan; Dose-Response Relationship, | 1987 |
Therapeutic options in chronic myeloid leukaemia.
Topics: Blast Crisis; Bone Marrow Transplantation; Busulfan; Humans; Hydroxyurea; Leukemia, Myelogenous, Chr | 1989 |
[Bone marrow transplantation in pediatric patients: review of progress].
Topics: Anemia, Aplastic; Blast Crisis; Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Graft vs | 1987 |
9 trials available for busulfan and Blast Phase
| Article | Year |
|---|---|
Extramedullary relapse following total marrow and lymphoid irradiation in patients undergoing allogeneic hematopoietic cell transplantation.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Blast Crisis; Bone Marrow; Busulfan; Ch | 2014 |
Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial.
Topics: Antineoplastic Agents, Alkylating; Blast Crisis; Busulfan; Female; Humans; Leukemia, Myelogenous, Ch | 1995 |
Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blast Crisis; Busulfan; Cross-Over Studies; Drug Resista | 1994 |
Randomized comparison of busulfan and hydroxyurea in chronic myelogenous leukemia: prolongation of survival by hydroxyurea. The German CML Study Group.
Topics: Blast Crisis; Busulfan; Drug Resistance; Female; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic | 1993 |
Successful treatment of accelerated and blastic phase of chronic myeloid leukemia with high-dose interferon alpha and hydroxyurea: a novel approach.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Antineoplastic Agents; Antineoplastic Combined | 1995 |
Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia.
Topics: Adult; Antineoplastic Agents, Alkylating; Blast Crisis; Bone Marrow Transplantation; Busulfan; Cyclo | 1999 |
Attempted prevention of blast crisis in chronic myeloid leukemia by the use of pulsed doses of cytarabine and lomustine. A Cancer and Leukemia Group B study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Busulfan; Cytarabine; Female; Follow-U | 1992 |
[Evaluation of 196 patients with chronic myeloid leukemia based on a standard prognosis model].
Topics: Biomarkers, Tumor; Blast Crisis; Busulfan; Clinical Trials as Topic; Female; Follow-Up Studies; Huma | 1990 |
Attempted prevention of blast crisis in chronic myeloid leukemia by the use of pulsed doses of cytosine arabinoside and cis-chloronitrosurea during the course of busulfan-maintained remission.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Busulfan; Clinical | 1988 |
16 other studies available for busulfan and Blast Phase
| Article | Year |
|---|---|
Imatinib combined with myeloablative allogeneic hematopoietic stem cell transplantation for advanced phases of chronic myeloid leukemia.
Topics: Adult; Benzamides; Blast Crisis; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cyclosporine | 2011 |
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.
Topics: Adolescent; Adult; Blast Crisis; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Free S | 2006 |
Prolonged imatinib-induced myelosuppression in chronic myeloid leukaemia with an unusually long survival.
Topics: Adult; Antineoplastic Agents; Benzamides; Blast Crisis; Busulfan; Fatal Outcome; Humans; Imatinib Me | 2008 |
Continuing immunoglobulin heavy chain gene rearrangements in chronic myeloid leukemia with recurrent B-lymphoid blast crises after bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Base Sequence; Blast Crisis; B | 1995 |
[Clinical study of chronic myelogenous leukemia].
Topics: Blast Crisis; Bone Marrow Transplantation; Busulfan; Granulocytes; Humans; Hydroxyurea; Interferon-a | 1993 |
Autologous blood stem cell transplantation followed by recombinant alpha interferon as treatment for patients with high-risk chronic myelogenous leukemia. A report of 32 cases.
Topics: Adult; Blast Crisis; Blood Component Transfusion; Blood Transfusion, Autologous; Bone Marrow Purging | 1993 |
Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blast Crisi | 1996 |
Clonally unrelated BCR-ABL-negative acute myeloblastic leukemia masquerading as blast crisis after busulphan and interferon therapy for BCR-ABL-positive chronic myeloid leukemia.
Topics: Acute Disease; Adult; Blast Crisis; Bone Marrow; Busulfan; Diagnosis, Differential; Female; Fusion P | 1999 |
Relapse of chronic myeloid leukemia (CML) in lymphoid crisis after allogeneic bone marrow transplantation for CML in chronic phase with busulfan plus cyclophosphamide regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Bu | 2002 |
The role of the MDR-1/P-170 mechanism in the development of multidrug resistance in chronic myeloid leukemia.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Busulfan; Drug Resistance; Ge | 1990 |
Biclonal analysis of busulfan-induced sister chromatid exchange in blast crisis of Philadelphia chromosome-positive chronic myeloid leukemia.
Topics: Blast Crisis; Busulfan; Cell Cycle; Diploidy; Drug Resistance; Humans; Leukemia, Myelogenous, Chroni | 1991 |
Chronic granulocytic leukaemia. A study of 160 cases.
Topics: Adolescent; Adult; Aged; Blast Crisis; Busulfan; Female; Follow-Up Studies; Hepatomegaly; Humans; In | 1990 |
Cytophotometry of granulocytes in chronic granulocytic leukaemia patients. Part II. Effects of chemotherapy on cell kinetics and cytochemical parameters of granulocytes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Busulfan; Cell Division; | 1987 |
Current treatment of chronic myelogenous leukemia.
Topics: Blast Crisis; Bone Marrow Transplantation; Busulfan; Humans; Hydroxyurea; Interferons; Leukemia, Mye | 1989 |
[Bone marrow aplasia without blast crisis in a case of CML of 10-year survival].
Topics: Adult; Anemia, Aplastic; Blast Crisis; Bone Marrow; Busulfan; Humans; Leukemia, Myelogenous, Chronic | 1989 |
[Early splenectomy in chronic granulocytic leukemia. 15 years' experience].
Topics: Adult; Blast Crisis; Busulfan; Combined Modality Therapy; Follow-Up Studies; Humans; Leukemia, Myelo | 1986 |