busulfan has been researched along with Azoospermia in 23 studies
Azoospermia: A condition of having no sperm present in the ejaculate (SEMEN).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs." | 8.12 | Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022) |
| "This study aimed at the efficacy of sequential treatment of bone marrow-derived mesenchymal stem cell secretion for busulfan-treated azoospermia in mice." | 8.02 | Secretions released from mesenchymal stem cells improve spermatogenesis restoration of cytotoxic treatment with busulfan in azoospermia mice. ( Cai, YT; Liu, TS; Qiu, F; Rao, JP; Shen, SL; Xiong, CL, 2021) |
| "Busulfan (Bus), is an alkylating agent widely used in chemotherapy which has been proven to possess toxic side effects on testicles." | 5.72 | Ameliorate effects of resveratrol and l-carnitine on the testicular tissue and sex hormones level in busulfan induced azoospermia rats. ( Forouzanfar, M; Hafezi, H; Shariatic, M; Vahdati, A, 2022) |
| "Busulfan is an alkylating chemotherapeutic agent that is routinely prescribed for leukemic patients to induce myelo-ablation." | 5.62 | The Therapeutic Potential of Amniotic Fluid-Derived Stem Cells on Busulfan-Induced Azoospermia in Adult Rats. ( El Mulla, KF; Ibrahim, HF; Medwar, AY; Safwat, SH; Zeitoun, TM, 2021) |
| "Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes." | 5.51 | Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019) |
| "In summary, we found that the intratesticular injection of low doses of Busulfan (5 mg/kg) is a relatively non-invasive and safe method for producing the rat azoospermia model causing the least toxicity on vital organs." | 4.12 | Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2022) |
| "Busulfan-induced testicular injury mouse models are commonly used for experiments on spermatogonial stem cell transplantation, treatments for azoospermia due to spermatogenic failure and preserving male fertility after chemotherapy." | 4.02 | Testicular quantitative ultrasound: A noninvasive monitoring method for evaluating spermatogenic function in busulfan-induced testicular injury mouse models. ( Deng, CH; Ding, L; Gao, Y; Hu, HT; Huang, WL; Lu, MD; Wang, Z; Xie, XY; Xie, Y; Yao, JH, 2021) |
| "The non-obstructive azoospermia (NOA) was induced in rats using intratesticular administration of Busulfan." | 4.02 | Amniotic fluid-derived exosomes improved spermatogenesis in a rat model of azoospermia. ( Heidarpour, M; Mahdipour, M; Mobarak, H; Nouri, M; Rahbarghazi, R, 2021) |
| "We established azoospermia models in 22 six-week-old male SD rats by intraperitoneal injection of busulfan at 20 mg per kg body weight." | 3.81 | [Bone marrow mesenchymal stem cells to repair the reproductive system of male azoospermia rats]. ( Ji, XP; Liu, DJ; Ma, YZ; Ren, Y; Wang, XH; Zhou, XY, 2015) |
| "Busulfan is a chemotherapeutic drug that induces sterility, azoospermia and testicular atrophy." | 3.80 | Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol. ( Akhondi, MM; Jafarian, A; Lakpour, N; Pejhan, N; Sadeghi, MR; Salehkhou, S, 2014) |
| "After establishing the feasibility of fiberoptic confocal fluorescent microscopy to identify antibody labeled sperm in vivo C57/B6 mice underwent intraperitoneal injection of busulfan to induce azoospermia." | 3.78 | Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval. ( Costabile, RA; Herr, JC; Kavoussi, PK; Lowe, GJ; Lysiak, JJ; Shetty, J; Smith, RP; Steers, WD, 2012) |
| "Busulfan (Bus), is an alkylating agent widely used in chemotherapy which has been proven to possess toxic side effects on testicles." | 1.72 | Ameliorate effects of resveratrol and l-carnitine on the testicular tissue and sex hormones level in busulfan induced azoospermia rats. ( Forouzanfar, M; Hafezi, H; Shariatic, M; Vahdati, A, 2022) |
| "Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes." | 1.51 | Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction. ( Abdi, S; Abdollahifar, MA; Azad, N; Ghasemi, A; Moradi, A; Piryaei, A; Rezaei, F; Ziaeipour, S, 2019) |
| "Non-obstructive azoospermia is the most challenging type of male infertility." | 1.40 | Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model. ( He, D; Li, X; Lin, T; Liu, X; Peng, J; Wei, G; Zhang, D; Zhang, Y; Zhu, J, 2014) |
| "The recent reports on the treatment of azoospermia patients, in which spermatozoa could not be traced in their testes, are focused more on the potential use of adult stem cells, like mesenchymal stem cells (MSCs)." | 1.39 | Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation. ( Aksoy, A; Buyrukcu, B; Cakici, C; Duruksu, G; Haliloglu, AH; Isık, A; Karaoz, E; Subası, C; Uludag, O; Ustun, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 11 (47.83) | 2.80 |
| Authors | Studies |
|---|---|
| Ganjibakhsh, M | 1 |
| Mehraein, F | 1 |
| Koruji, M | 2 |
| Bashiri, Z | 1 |
| Mobarak, H | 2 |
| Rahbarghazi, R | 2 |
| Nouri, M | 2 |
| Heidarpour, M | 2 |
| Mahdipour, M | 2 |
| Hafezi, H | 1 |
| Vahdati, A | 1 |
| Forouzanfar, M | 1 |
| Shariatic, M | 1 |
| Mafi Balani, M | 1 |
| Ghafari Novin, M | 1 |
| Sabbagh Alvani, M | 1 |
| Raee, P | 1 |
| Afshar, A | 1 |
| Aghajanpour, F | 1 |
| Soltani, R | 1 |
| Hassani Moghaddam, M | 1 |
| Fathi, M | 1 |
| Vakili, K | 1 |
| Salimi, M | 1 |
| Hasani, AHS | 1 |
| Abdi, S | 2 |
| Abdollahifar, MA | 2 |
| Aliaghaei, A | 1 |
| Ziaeipour, S | 1 |
| Rezaei, F | 1 |
| Piryaei, A | 2 |
| Moradi, A | 1 |
| Ghasemi, A | 1 |
| Azad, N | 1 |
| Lei, B | 1 |
| Xie, L | 1 |
| Zhang, S | 1 |
| Lv, D | 1 |
| Shu, F | 1 |
| Deng, Y | 1 |
| Badawy, AA | 1 |
| El-Magd, MA | 1 |
| AlSadrah, SA | 1 |
| Alruwaili, MM | 1 |
| Chen, Z | 1 |
| Liu, M | 1 |
| Hu, JH | 1 |
| Gao, Y | 2 |
| Deng, C | 3 |
| Jiang, MH | 1 |
| Huang, WL | 1 |
| Ding, L | 1 |
| Yao, JH | 1 |
| Hu, HT | 1 |
| Xie, XY | 1 |
| Lu, MD | 1 |
| Deng, CH | 1 |
| Xie, Y | 2 |
| Wang, Z | 1 |
| Ibrahim, HF | 1 |
| Safwat, SH | 1 |
| Zeitoun, TM | 1 |
| El Mulla, KF | 1 |
| Medwar, AY | 1 |
| Cai, YT | 1 |
| Xiong, CL | 1 |
| Liu, TS | 1 |
| Shen, SL | 1 |
| Rao, JP | 1 |
| Qiu, F | 1 |
| Huang, Y | 1 |
| Zhao, L | 1 |
| Yao, C | 1 |
| Yang, C | 1 |
| Zhu, Z | 1 |
| Li, P | 1 |
| Tian, R | 1 |
| Chen, H | 2 |
| He, Z | 1 |
| Li, Z | 1 |
| Zhang, C | 1 |
| Ouyang, B | 1 |
| Lv, L | 1 |
| Yao, J | 1 |
| Liang, X | 1 |
| Zhang, Y | 3 |
| Sun, X | 1 |
| Liu, G | 1 |
| Cakici, C | 1 |
| Buyrukcu, B | 1 |
| Duruksu, G | 1 |
| Haliloglu, AH | 1 |
| Aksoy, A | 1 |
| Isık, A | 1 |
| Uludag, O | 1 |
| Ustun, H | 1 |
| Subası, C | 1 |
| Karaoz, E | 1 |
| Jafarian, A | 1 |
| Sadeghi, MR | 1 |
| Pejhan, N | 1 |
| Salehkhou, S | 1 |
| Lakpour, N | 1 |
| Akhondi, MM | 1 |
| Zhang, D | 1 |
| Liu, X | 1 |
| Peng, J | 1 |
| He, D | 1 |
| Lin, T | 1 |
| Zhu, J | 1 |
| Li, X | 1 |
| Wei, G | 1 |
| Zhou, XY | 1 |
| Ma, YZ | 1 |
| Wang, XH | 1 |
| Liu, DJ | 1 |
| Ren, Y | 1 |
| Ji, XP | 1 |
| Wu, C | 1 |
| Shen, Q | 1 |
| Zhou, Z | 1 |
| Liu, W | 1 |
| Hua, J | 1 |
| Smith, RP | 1 |
| Lowe, GJ | 1 |
| Kavoussi, PK | 1 |
| Steers, WD | 1 |
| Costabile, RA | 1 |
| Herr, JC | 1 |
| Shetty, J | 1 |
| Lysiak, JJ | 1 |
| Shahverdi, A | 1 |
| Janan, A | 1 |
| Lakpour, MR | 1 |
| Gilani Sedighi, MA | 1 |
| Sun, H | 1 |
| Yang, B | 1 |
| Zhu, C | 1 |
| Liu, R | 1 |
| Wang, H | 1 |
| Li, W | 1 |
| Huang, XB | 1 |
| Li, HG | 1 |
23 other studies available for busulfan and Azoospermia
| Article | Year |
|---|---|
The therapeutic potential of adipose tissue-derived mesenchymal stromal cells in the treatment of busulfan-induced azoospermic mice.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Immunosuppressive Agents; Male; Mesenchymal | 2022 |
Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Humans; Injections; Injections, Intraperiton | 2022 |
Ameliorate effects of resveratrol and l-carnitine on the testicular tissue and sex hormones level in busulfan induced azoospermia rats.
Topics: Animals; Azoospermia; Busulfan; Carnitine; Follicle Stimulating Hormone; Male; Rats; Resveratrol; Ro | 2022 |
An elderberry-supplemented diet improves spermatogenesis in mice with busulfan-induced azoospermia.
Topics: Animals; Azoospermia; Busulfan; Diet; Humans; Male; Mice; Sambucus; Seeds; Spermatogenesis; Testis | 2022 |
Hyperthermia versus busulfan: Finding the effective method in animal model of azoospermia induction.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Fever; Male; Mice; Organ Size; Sperm Count; | 2019 |
UBE2W down-regulation promotes cell apoptosis and correlates with hypospermatogenesis.
Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Dimethyl Sulfoxide; Disease Models, Animal; Do | 2020 |
Altered expression of some miRNAs and their target genes following mesenchymal stem cell treatment in busulfan-induced azoospermic rats.
Topics: Animals; Azoospermia; Busulfan; Down-Regulation; Female; Fertility; Male; Mesenchymal Stem Cells; Mi | 2020 |
Substance P restores spermatogenesis in busulfan-treated mice: A new strategy for male infertility therapy.
Topics: Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Ex | 2021 |
Testicular quantitative ultrasound: A noninvasive monitoring method for evaluating spermatogenic function in busulfan-induced testicular injury mouse models.
Topics: Animals; Azoospermia; Busulfan; Humans; Male; Mice; Spermatogenesis; Spermatogonia; Testis | 2021 |
The Therapeutic Potential of Amniotic Fluid-Derived Stem Cells on Busulfan-Induced Azoospermia in Adult Rats.
Topics: Aged; Amniotic Fluid; Animals; Antineoplastic Agents, Alkylating; Azoospermia; Busulfan; Female; Hum | 2021 |
Amniotic fluid-derived exosomes improved spermatogenesis in a rat model of azoospermia.
Topics: Alkylating Agents; Amniotic Fluid; Animals; Azoospermia; Busulfan; Exosomes; Male; Rats; Rats, Wista | 2021 |
Secretions released from mesenchymal stem cells improve spermatogenesis restoration of cytotoxic treatment with busulfan in azoospermia mice.
Topics: Animals; Azoospermia; Busulfan; Humans; Male; Mesenchymal Stem Cells; Mice; Sertoli Cells; Spermatog | 2021 |
Effect of Kallikrein-related Peptidase KLK1 on Ameliorating Spermatogenesis Regeneration in Busulfan-induced Azoospermic Mice and Promoting Mouse Spermatogonial Stem Cell Proliferation In Vitro.
Topics: Animals; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Disease Models, Animal; Humans; Injec | 2018 |
Urine-Derived Stem Cells Facilitate Endogenous Spermatogenesis Restoration of Busulfan-Induced Nonobstructive Azoospermic Mice by Paracrine Exosomes.
Topics: Animals; Azoospermia; Biomarkers; Bioreactors; Busulfan; Cell Cycle Proteins; Culture Media; DNA-Bin | 2019 |
Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation.
Topics: Adipose Tissue; Animals; Azoospermia; Busulfan; Cell Differentiation; Female; Fertility; Green Fluor | 2013 |
Regeneration of spermatogenesis in a mouse model of azoospermia by follicle-stimulating hormone and oestradiol.
Topics: Animals; Azoospermia; Busulfan; Cyclin B1; Disease Models, Animal; Estradiol; Follicle Stimulating H | 2014 |
Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model.
Topics: Animals; Antineoplastic Agents; Azoospermia; Bone Marrow Cells; Busulfan; Cell Transdifferentiation; | 2014 |
[Bone marrow mesenchymal stem cells to repair the reproductive system of male azoospermia rats].
Topics: Animals; Azoospermia; Biomarkers; Bone Marrow Cells; Busulfan; Cell Membrane; Epididymis; Hyaluronan | 2015 |
Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse.
Topics: Adult Germline Stem Cells; Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; | 2016 |
Confocal fluorescence microscopy in a murine model of microdissection testicular sperm extraction to improve sperm retrieval.
Topics: Animals; Azoospermia; Busulfan; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Microdissect | 2012 |
Proliferation of small number of human spermatogonial stem cells obtained from azoospermic patients.
Topics: Analysis of Variance; Animals; Azoospermia; Biomarkers; Biopsy; Busulfan; Cell Count; Cell Culture T | 2012 |
Presence of metastasis-associated protein 1 in Sertoli cells is required for proper contact between Sertoli cells and adjacent germ cells.
Topics: Adherens Junctions; Adult; Alkylating Agents; Animals; Azoospermia; Busulfan; Calcium Channels, N-Ty | 2013 |
[Establishment of an animal model of azoospermia in male mice].
Topics: Animals; Azoospermia; Busulfan; Cyclophosphamide; Disease Models, Animal; Estradiol; Injections, Int | 2007 |