Page last updated: 2024-10-24

busulfan and Autosomal Recessive Chronic Granulomatous Disease

busulfan has been researched along with Autosomal Recessive Chronic Granulomatous Disease in 21 studies

Research Excerpts

ExcerptRelevanceReference
" Graft-versus-host disease prophylaxis consisted of cyclosporine A and, for unrelated donors, short course of methotrexate and anti-T-lymphocyte globulin."3.77Allogeneic haematopoietic stem cell transplantation as therapy for chronic granulomatous disease--single centre experience. ( Baran, J; Czogała, W; Goździk, J; Krasowska-Kwiecień, A; Pituch-Noworolska, A; Skoczeń, S; Wędrychowicz, A; Wiecha, O; Zembala, M, 2011)
"Busulfan was administered mainly intravenously and exceptionally orally from days -5 to -3."2.79Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study. ( Ahmad, I; Albert, MH; Belohradsky, BH; Bredius, R; Fasth, A; Fernandes, JF; Fischer, A; Gaspar, HB; Gennery, A; Gruhn, B; Güngör, T; Haddad, E; Hassan, M; Hough, R; Kentouche, K; Lachance, S; Moshous, D; Rentsch, K; Resnick, IB; Schanz, U; Schlegel, PG; Seger, R; Shaw, PJ; Slatter, M; Stepensky, P; Stussi, G; Teira, P; Telles da Cunha, JM; Vermont, C; Veys, P, 2014)
"Exacerbation of infection during aplasia was observed in 3 patients; inflammatory flare at the infection site during neutrophil engraftment in 2: all 5 patients belonged to the subgroup of 9 with pre-existing infection."2.41Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000. ( Belohradsky, BH; Blanche, S; Bordigoni, P; Cant, A; Di Bartolomeo, P; Fischer, A; Flood, T; Gungor, T; Landais, P; Müller, S; Nagler, A; Ozsahin, H; Passwell, JH; Porta, F; Seger, RA; Slavin, S; Wulffraat, N; Zintl, F, 2002)
" Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is curative and safe at the pediatric age but remains underperformed in adults."1.72Curative allogeneic hematopoietic stem cell transplantation following reduced toxicity conditioning in adults with primary immunodeficiency. ( Asnafi, V; Catherinot, É; Cheminant, M; Couderc, LJ; Fischer, A; Hermine, O; Jeljeli, M; Lanternier, F; Lortholary, O; Mahlaoui, N; Marçais, A; Moshous, D; Neven, B; Picard, C; Salvator, H; Suarez, F; van Endert, P, 2022)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's2 (9.52)18.2507
2000's5 (23.81)29.6817
2010's9 (42.86)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Marçais, A1
Mahlaoui, N1
Neven, B1
Lanternier, F1
Catherinot, É1
Salvator, H1
Cheminant, M1
Jeljeli, M1
Asnafi, V1
van Endert, P1
Couderc, LJ1
Lortholary, O1
Picard, C1
Moshous, D2
Hermine, O1
Fischer, A3
Suarez, F1
Jacoby, E1
Adam, E1
Hutt, D1
Somech, R1
Malkiel, S1
Toren, A1
Bielorai, B1
Kapoor, R1
Rastogi, N1
Yadav, SP1
Osumi, T1
Tomizawa, D1
Kawai, T1
Sako, M1
Inoue, E1
Takimoto, T1
Tamura, E1
Uchiyama, T1
Imadome, KI1
Taniguchi, M1
Shirai, R1
Yoshida, M1
Ando, R1
Tsumura, Y1
Fuji, H1
Matsumoto, K2
Shioda, Y1
Kiyotani, C1
Terashima, K1
Onodera, M1
Kato, M1
Arnold, DE1
Seif, AE1
Jyonouchi, S1
Sullivan, KE1
Bunin, NJ1
Heimall, JR1
Güngör, T2
Teira, P1
Slatter, M2
Stussi, G1
Stepensky, P1
Vermont, C1
Ahmad, I1
Shaw, PJ1
Telles da Cunha, JM1
Schlegel, PG1
Hough, R1
Fasth, A1
Kentouche, K1
Gruhn, B1
Fernandes, JF1
Lachance, S1
Bredius, R1
Resnick, IB1
Belohradsky, BH2
Gennery, A1
Gaspar, HB1
Schanz, U1
Seger, R1
Rentsch, K1
Veys, P2
Haddad, E1
Albert, MH1
Hassan, M2
Oshrine, B1
Morsheimer, M1
Heimall, J1
Bunin, N1
Morillo-Gutierrez, B1
Beier, R1
Rao, K1
Burroughs, L1
Schulz, A2
Ewins, AM1
Gibson, B1
Sedlacek, P1
Krol, L1
Strahm, B1
Zaidman, I1
Kalwak, K2
Talano, JA1
Woolfrey, A1
Fraser, C1
Meyts, I1
Müller, I1
Wachowiak, J1
Bernardo, ME1
Sykora, KW1
Gennery, AR1
Zhou, L1
Dong, LJ1
Gao, ZY1
Yu, XJ1
Lu, DP1
Schuetz, C1
Hoenig, M1
Gatz, S1
Speth, F1
Benninghoff, U1
Debatin, KM1
Friedrich, W1
Klaudel-Dreszler, MA1
Kurenko-Deptuch, M1
Wolska-Kusnierz, B1
Heropolitanska-Pliszka, E1
Pietrucha, B1
Mikoluc, B1
Gorczyńska, E1
Ussowicz, M1
Chybicka, A1
Bernatowska, E1
Kang, EM1
Choi, U1
Theobald, N1
Linton, G1
Long Priel, DA1
Kuhns, D1
Malech, HL1
Goździk, J1
Pituch-Noworolska, A1
Skoczeń, S1
Czogała, W1
Wędrychowicz, A1
Baran, J1
Krasowska-Kwiecień, A1
Wiecha, O1
Zembala, M1
Garming-Legert, K1
Remberger, M1
Ringdén, O1
Dahllöf, G1
Seger, RA1
Blanche, S1
Bordigoni, P1
Di Bartolomeo, P1
Flood, T1
Landais, P1
Müller, S1
Ozsahin, H1
Passwell, JH1
Porta, F1
Slavin, S1
Wulffraat, N1
Zintl, F1
Nagler, A1
Cant, A1
Del Giudice, I1
Iori, AP1
Mengarelli, A1
Testi, AM1
Romano, A1
Cerretti, R1
Macrì, F1
Iacobini, M1
Arcese, W1
Ariga, T1
Kamani, N1
August, CS1
Douglas, SD1
Burkey, E1
Etzioni, A1
Lischner, HW1
Calviño, MC1
Maldonado, MS1
Otheo, E1
Muñoz, A1
Couselo, JM1
Burgaleta, C1
Leung, T1
Chik, K1
Li, C1
Shing, M1
Yuen, P1
Thompson, EN1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicentric, Exploratory, Non-randomised, Non-controlled, Prospective, Open-label Phase II Study Evaluating Safety and Efficacy of IBU, G-CSF and Plerixafor as Stem Cell Mobilization Regimen in Patients Affected by X-CGD[NCT03055247]Phase 23 participants (Anticipated)Interventional2015-11-06Recruiting
Autologous Transplantation of Genetically Modified Cells for the Treatment of X-Linked Chronic Granulomatous Disease[NCT00394316]Early Phase 13 participants (Actual)Interventional2006-10-30Terminated
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency[NCT01306019]Phase 1/Phase 219 participants (Actual)Interventional2012-09-25Suspended (stopped due to Clones representing 10% or more of the subject patients myeloid lineage have been detected, no evidence of malignancy found.)
HLA-Matched, Peripheral Blood Stem Cell Transplantation Using Low Intensity Conditioning to Treat Patients With Chronic Granulomatous Disease Who Are Actively Infected[NCT00006417]Phase 210 participants Interventional2000-10-31Completed
Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care[NCT00023192]Phase 360 participants Interventional2001-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for busulfan and Autosomal Recessive Chronic Granulomatous Disease

ArticleYear
Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000.
    Blood, 2002, Dec-15, Volume: 100, Issue:13

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodie

2002
Allogeneic stem cell transplant from HLA-identical sibling for chronic granulomatous disease and review of the literature.
    Annals of hematology, 2003, Volume: 82, Issue:3

    Topics: Bone Marrow Transplantation; Busulfan; Child; Chromosomes, Human, X; Cyclophosphamide; Genetic Linka

2003
[Gene therapy for primary immunodeficiency diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 12

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Deaminase; Busulfan; DNA-Binding Proteins; Genetic T

2005
Bone marrow transplantation for chronic granulomatous disease: long-term follow-up and review of literature.
    Bone marrow transplantation, 1999, Volume: 24, Issue:5

    Topics: Bone Marrow Transplantation; Busulfan; Child; Coloring Agents; Cyclophosphamide; Female; Granulomato

1999

Trials

4 trials available for busulfan and Autosomal Recessive Chronic Granulomatous Disease

ArticleYear
A prospective study of allogeneic transplantation from unrelated donors for chronic granulomatous disease with target busulfan-based reduced-intensity conditioning.
    Bone marrow transplantation, 2019, Volume: 54, Issue:1

    Topics: Adolescent; Allografts; Busulfan; Child; Child, Preschool; Granulomatous Disease, Chronic; Hematopoi

2019
Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.
    Lancet (London, England), 2014, Feb-01, Volume: 383, Issue:9915

    Topics: Adolescent; Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Busulfan; C

2014
Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience.
    Blood, 2016, 07-21, Volume: 128, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Allografts; Blood Platelets; Busulfan; Child; Child, Preschool; Di

2016
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
    Blood, 2010, Jan-28, Volume: 115, Issue:4

    Topics: Adult; Aspergillosis; Busulfan; Chromosomes, Human, X; Combined Modality Therapy; Genetic Therapy; G

2010

Other Studies

13 other studies available for busulfan and Autosomal Recessive Chronic Granulomatous Disease

ArticleYear
Curative allogeneic hematopoietic stem cell transplantation following reduced toxicity conditioning in adults with primary immunodeficiency.
    Bone marrow transplantation, 2022, Volume: 57, Issue:10

    Topics: Adolescent; Adult; Busulfan; Child; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematopoi

2022
Improved Outcome Following Busulfan-Based Conditioning in Children with Functional Neutrophil Disorders Undergoing Hematopoietic Stem Cell Transplant from HLA-Matched Donors.
    Journal of clinical immunology, 2023, Volume: 43, Issue:7

    Topics: Busulfan; Child; Child, Preschool; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematopoie

2023
Haploidentical Stem Cell Transplant With Post Transplant Cyclophosphamide for Chronic Granulomatous Disease With Thiotepa, Busulfan, and Fludarabine as Conditioning.
    Journal of pediatric hematology/oncology, 2021, 05-01, Volume: 43, Issue:4

    Topics: Antineoplastic Agents; Busulfan; Child, Preschool; Cyclophosphamide; Granulomatous Disease, Chronic;

2021
Allogeneic hematopoietic stem cell transplantation in adolescent patients with chronic granulomatous disease.
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:3

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Female; Graft vs Host Disease; Granulomatous Disease,

2019
Reduced-intensity conditioning for hematopoietic cell transplantation of chronic granulomatous disease.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:2

    Topics: Alemtuzumab; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Busulfan; Child, Preschool; Gr

2015
Haploidentical hematopoietic stem cell transplantation for a case with X-linked chronic granulomatous disease.
    Pediatric transplantation, 2017, Volume: 21, Issue:1

    Topics: Adolescent; Busulfan; Chromosomes, Human, X; Cyclophosphamide; Granulomatous Disease, Chronic; Hemat

2017
Hematopoietic stem cell transplantation from matched unrelated donors in chronic granulomatous disease.
    Immunologic research, 2009, Volume: 44, Issue:1-3

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Chimerism; Cyclophosphamide; Follow-Up Studies; Granu

2009
Treosulfan-based conditioning regimen in a second matched unrelated peripheral blood stem cell transplantation for a pediatric patient with CGD and invasive aspergillosis, who experienced initial graft failure after RIC.
    International journal of hematology, 2009, Volume: 90, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Aspergillosis; Busulfan; Child, Preschool; Graft Survival; Granul

2009
Allogeneic haematopoietic stem cell transplantation as therapy for chronic granulomatous disease--single centre experience.
    Journal of clinical immunology, 2011, Volume: 31, Issue:3

    Topics: Adolescent; Antigens, CD; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease

2011
Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI.
    Oral diseases, 2011, Volume: 17, Issue:7

    Topics: Adolescent; Age Factors; Anemia, Aplastic; Area Under Curve; Busulfan; Cyclophosphamide; Dose Fracti

2011
Bone marrow transplantation in chronic granulomatous disease.
    The Journal of pediatrics, 1984, Volume: 105, Issue:1

    Topics: Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Granulomatous Disease, Chronic; Heterozygot

1984
Bone marrow transplantation in chronic granulomatous disease.
    European journal of pediatrics, 1996, Volume: 155, Issue:10

    Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Cyclophosphamide; Granulomatous Disease, Ch

1996
Proceedings: Chronic granulomatous disease.
    Journal of clinical pathology, 1974, Volume: 27, Issue:11

    Topics: Adult; Busulfan; Child; Female; Granulomatous Disease, Chronic; Humans; Leukocytosis; Male; Phagocyt

1974