Page last updated: 2024-10-24

busulfan and Antibody Deficiency Syndrome

busulfan has been researched along with Antibody Deficiency Syndrome in 19 studies

Research Excerpts

ExcerptRelevanceReference
"X-linked EDA-ID1 (ectodermal dysplasia, anhidrotic, with immunodeficiency 1, Online Mendelian Inheritance in Man [OMIM] 300291), or NEMO (nuclear factor kappa B essential modulator) deficiency syndrome, is caused by mutations in the IKBKG/NEMO gene."1.56Successful Allogeneic Stem Cell Transplantation in Nuclear Factor-Kappa B Essential Modulator Deficiency Syndrome After Treosulfan-Based Conditioning: A Case Report. ( Bąbol-Pokora, K; Dąbrowska-Leonik, N; Frączkiewicz, J; Gul, K; Janeczko-Czarnecka, M; Kałwak, K; Martuszewski, A; Mielcarek-Siedziuk, M; Młynarski, W; Nowak, M; Paluszkiewicz, P; Salamonowicz-Bodzioch, M; Sierżęga-Staykov, K; Ussowicz, M; Wawrzyniak-Dzierżek, E; Wolska-Kuśnierz, B, 2020)
"Busulfan was quantitated using ultraviolet absorbance detection after derivatization and HPLC separation."1.32Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation. ( Blazar, B; Bostrom, B; Bruns, A; Enockson, K; Johnson, A, 2003)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's3 (15.79)18.2507
2000's5 (26.32)29.6817
2010's5 (26.32)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Carruthers, VA1
Lum, SH1
Flood, T3
Slatter, MA4
Gennery, AR4
Martuszewski, A2
Paluszkiewicz, P2
Wawrzyniak-Dzierżek, E2
Drożyńska-Duklas, M1
Bąbol-Pokora, K2
Myśliwiec, M1
Szymczak, D1
Irga-Jaworska, N1
Młynarski, W2
Kałwak, K2
Ussowicz, M2
Sierżęga-Staykov, K1
Salamonowicz-Bodzioch, M1
Frączkiewicz, J1
Janeczko-Czarnecka, M1
Mielcarek-Siedziuk, M1
Nowak, M1
Dąbrowska-Leonik, N1
Wolska-Kuśnierz, B1
Gul, K1
Ishiwata, Y1
Nagata, M1
Tsuge, K1
Takahashi, H1
Suzuki, S1
Imai, K1
Takagi, M1
Kanegane, H1
Morio, T2
Yasuhara, M1
Rao, K2
Abd Hamid, IJ1
Nademi, Z2
Chiesa, R1
Elfeky, R1
Pearce, MS1
Amrolia, P2
Worth, A1
Abinun, M3
Hambleton, S2
Qasim, W2
Gaspar, HB2
Cant, AJ2
Veys, P2
Haskoloğlu, Ş1
Köstel Bal, S1
İslamoğlu, C1
Altun, D1
Kendirli, T1
Doğu, EF1
İkincioğulları, A1
Goulden, N1
Davies, G1
Cant, A1
Bostrom, B1
Enockson, K1
Johnson, A1
Bruns, A1
Blazar, B1
Nagasawa, M1
Itoh, S1
Sawada, Y1
Nonoyama, S1
Mizutani, S1
Cheetham, TD1
Bhattacharya, A1
Crooks, BN1
Flood, TJ1
Bakker, B1
Oostdijk, W1
Bresters, D1
Walenkamp, MJ1
Vossen, JM2
Wit, JM1
Ariga, T1
van Tol, MJ1
Gerritsen, EJ1
de Lange, GG1
van Leeuwen, AM1
Jol-van der Zijde, CM1
Oudeman-Gruber, NJ1
de Vries, E1
Radl, J1
Basch, RS1
Quito, FL1
Beh, J1
Hirst, JA1
Storb, R1
Weiden, PL1
Graham, TC1
Thomas, ED1
Guseva, SA1
Hobbs, JR1
Hugh-Jones, K1
Pawelec, G1
Schmidt, H1
Schneider, E1
Bühring, HJ1
Ehninger, G1
Marcovitch, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Treosulfan Pharmacokinetics (PK) in Children Undergoing Allogeneic Haematopoietic Stem Cell Transplantation (HSCT)[NCT02048800]61 participants (Actual)Observational2014-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for busulfan and Antibody Deficiency Syndrome

ArticleYear
[Gene therapy for primary immunodeficiency diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 12

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Deaminase; Busulfan; DNA-Binding Proteins; Genetic T

2005
Studies of marrow transplantation in dogs.
    Transplantation proceedings, 1976, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Anal Gland Neoplasms; Animals; Blood Transfusion; Bone Marrow Cells; Bone Marrow Tra

1976

Trials

2 trials available for busulfan and Antibody Deficiency Syndrome

ArticleYear
Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Alemtuzumab; Allografts; Busulfan; Child; Child, Preschool; Disease-Free Survival

2018
[Characteristics of the effect of myelosan on the immune status of patients with chronic myeloid leukemia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:8

    Topics: Adjuvants, Immunologic; B-Lymphocytes; Busulfan; Humans; Immunity; Immunoglobulins; Immunologic Defi

1992

Other Studies

15 other studies available for busulfan and Antibody Deficiency Syndrome

ArticleYear
Hematopoietic Cell Transplant for CD40 Ligand Deficiency-Comparing Busulfan Versus Treosulfan.
    Journal of clinical immunology, 2022, Volume: 42, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Busulfan; CD40 Ligand; Hematopoietic Stem Cell Transplantation; H

2022
Successful Salvage Haploidentical Alpha-Beta T Cell-Depleted Stem Cell Transplantation After Busulfan-Based Myeloablation in a Patient With IPEX Syndrome: A Case Report.
    Transplantation proceedings, 2019, Volume: 51, Issue:9

    Topics: Antilymphocyte Serum; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Huma

2019
Successful Allogeneic Stem Cell Transplantation in Nuclear Factor-Kappa B Essential Modulator Deficiency Syndrome After Treosulfan-Based Conditioning: A Case Report.
    Transplantation proceedings, 2020, Volume: 52, Issue:2

    Topics: Antilymphocyte Serum; Busulfan; Ectodermal Dysplasia; Hematopoietic Stem Cell Transplantation; Human

2020
Population Pharmacokinetics of Intravenous Busulfan in Japanese Pediatric Patients With Primary Immunodeficiency Diseases.
    Journal of clinical pharmacology, 2018, Volume: 58, Issue:3

    Topics: Administration, Intravenous; Adolescent; Asian People; Busulfan; Child; Child, Preschool; Female; He

2018
Outcome of treosulfan-based reduced-toxicity conditioning regimens for HSCT in high-risk patients with primary immune deficiencies.
    Pediatric transplantation, 2018, Volume: 22, Issue:7

    Topics: Adolescent; Busulfan; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combinati

2018
Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience.
    Blood, 2011, Apr-21, Volume: 117, Issue:16

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Chimerism; Cohort

2011
Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation.
    Pediatric transplantation, 2003, Volume: 7 Suppl 3

    Topics: Adolescent; Adult; Area Under Curve; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool;

2003
Coagulopathy in a patient with X-linked hyper-IgM syndrome who developed Kaposi's sarcoma.
    American journal of hematology, 2004, Volume: 75, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Chromos

2004
Thyroid dysfunction after bone marrow transplantation for primary immunodeficiency without the use of total body irradiation in conditioning.
    Bone marrow transplantation, 2004, Volume: 33, Issue:9

    Topics: Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Hy

2004
Disturbances of growth and endocrine function after busulphan-based conditioning for haematopoietic stem cell transplantation during infancy and childhood.
    Bone marrow transplantation, 2004, Volume: 33, Issue:10

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Body Height; Busulfan; Calcium; Child; Child, Prescho

2004
The origin of IgG production and homogeneous IgG components after allogeneic bone marrow transplantation.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Anemia, Aplastic; B-Lymphocytes; Bone Marrow; Bone Marrow Transplantation; Busulfan; Cell Survival;

1996
Growth of human hematopoietic cells in immunodeficient mice conditioned with cyclophosphamide and busulfan.
    Stem cells (Dayton, Ohio), 1997, Volume: 15, Issue:4

    Topics: Adult; Animals; Antigens, CD34; Bone Marrow; Bone Marrow Cells; Busulfan; Cell Count; Cell Division;

1997
Immunodeficiencies better treated by transplantation.
    The Tokai journal of experimental and clinical medicine, 1985, Volume: 10, Issue:2-3

    Topics: B-Lymphocytes; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Fetus; Haploidy; Histocompat

1985
Cellular immunological defects of chronic myelogenous leukaemics: partial dependence on busulphan therapy.
    Cancer immunology, immunotherapy : CII, 1988, Volume: 27, Issue:1

    Topics: Antigens, Differentiation; Antigens, Surface; Busulfan; HLA-DP Antigens; HLA-DR Antigens; Humans; Im

1988
Chronic granulomatous disease of childhood.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Anti-Bacterial Agents; Busulfan; Child; Child, Preschool; Chronic Disease; Coloring Agents; Female;

1970