Page last updated: 2024-10-24

busulfan and Anaplastic Ependymoma

busulfan has been researched along with Anaplastic Ependymoma in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Intrathecal Spartaject Busulfan was well tolerated in children with neoplastic meningitis from brain tumors, and the recommended dose for future phase II studies is 13 mg."9.12Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). ( Blaney, SM; Bomgaars, L; Boyett, JM; Friedman, HS; Gururangan, S; Hancock, ML; Kun, LE; Petros, WP; Phillips, PC; Poussaint, TY, 2006)
"Intrathecal Spartaject Busulfan was well tolerated in children with neoplastic meningitis from brain tumors, and the recommended dose for future phase II studies is 13 mg."5.12Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). ( Blaney, SM; Bomgaars, L; Boyett, JM; Friedman, HS; Gururangan, S; Hancock, ML; Kun, LE; Petros, WP; Phillips, PC; Poussaint, TY, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gururangan, S1
Petros, WP1
Poussaint, TY1
Hancock, ML1
Phillips, PC1
Friedman, HS3
Bomgaars, L1
Blaney, SM1
Kun, LE1
Boyett, JM1
Grill, J2
Kalifa, C2
Doz, F1
Schoepfer, C1
Sainte-Rose, C1
Couanet, D1
Terrier-Lacombe, MJ1
Valteau-Couanet, D1
Hartmann, O1
Graham, ML1
Herndon, JE1
Casey, JR1
Chaffee, S1
Ciocci, GH1
Krischer, JP1
Kurtzberg, J1
Laughlin, MJ1
Longee, DC1
Olson, JF1
Paleologus, N1
Pennington, CN1
Coggins, CA1
Elion, GB1
Houghton, PJ1
Hare, CB1
Keir, S1
Colvin, OM1
Bigner, DD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I Study of Intrathecal Spartaject-Busulfan in Children With Neoplastic Meningitis[NCT00006246]Phase 128 participants (Actual)Interventional2000-11-30Completed
A Phase II Study of Intraventricular Methotrexate With Systemic Topotecan and Cyclophosphamide in Children With Recurrent or Progressive Malignant Brain Tumors[NCT02684071]Phase 23 participants (Actual)Interventional2016-02-29Terminated (stopped due to Lack of additional funding; patients (3) no longer receiving intervention.)
Phase II, Single Arm, Open Label Clinical Trial With Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas[NCT01574092]Phase 239 participants (Actual)Interventional2009-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for busulfan and Anaplastic Ependymoma

ArticleYear
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Choroid Ple

2006
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Choroid Ple

2006
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Choroid Ple

2006
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Choroid Ple

2006
A high-dose busulfan-thiotepa combination followed by autologous bone marrow transplantation in childhood recurrent ependymoma. A phase-II study.
    Pediatric neurosurgery, 1996, Volume: 25, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neopl

1996

Other Studies

3 other studies available for busulfan and Anaplastic Ependymoma

ArticleYear
High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brai

1997
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:6

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Camptothecin; Carmusti

1998
High dose chemotherapy for childhood ependymona.
    Journal of neuro-oncology, 1998, Volume: 40, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

1998