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buspirone and Smoking Cessation

buspirone has been researched along with Smoking Cessation in 9 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Smoking Cessation: Discontinuing the habit of SMOKING.

Research Excerpts

ExcerptRelevanceReference
"One hundred one smokers were divided into high and low trait anxiety groups on the basis of a normalized score on the Profile of Mood States Anxiety/Tension Scale and were randomly assigned to receive buspirone or placebo in a double-blind fashion."9.08A placebo-controlled evaluation of the effects of buspirone on smoking cessation: differences between high- and low-anxiety smokers. ( Cinciripini, PM; Lapitsky, L; Meyer, WJ; Seay, S; van Vunakis, H; Wallfisch, A, 1995)
"Buspirone, a non-sedating anxiolytic, has yielded contradictory results in smoking cessation pilot studies and trials."9.08Efficacy of buspirone in smoking cessation: a placebo-controlled trial. ( Brown, HV; Daims, RM; Olmstead, RE; Schneider, NG; Sloan, K; Steinberg, C, 1996)
"Before smoking cessation, there were no significant differences in the intensity of any withdrawal symptom between the buspirone- and placebo-treated subjects, with the exception of a significantly higher rating for drowsiness in the buspirone group."9.07Effect of buspirone on withdrawal symptoms associated with smoking cessation. ( Del Core, MG; Hilleman, DE; Mohiuddin, SM; Sketch, MH, 1992)
"Buspirone was started 21 days before the quit attempt and continued for 7 days after the quit attempt."6.67Comparison of fixed-dose transdermal nicotine, tapered-dose transdermal nicotine, and buspirone in smoking cessation. ( Delcore, MG; Hilleman, DE; Mohiuddin, SM, 1994)
"Buspirone, a non-sedating anxiolytic, has yielded contradictory results in smoking cessation pilot studies and trials."5.08Efficacy of buspirone in smoking cessation: a placebo-controlled trial. ( Brown, HV; Daims, RM; Olmstead, RE; Schneider, NG; Sloan, K; Steinberg, C, 1996)
"Before smoking cessation, there were no significant differences in the intensity of any withdrawal symptom between the buspirone- and placebo-treated subjects, with the exception of a significantly higher rating for drowsiness in the buspirone group."5.07Effect of buspirone on withdrawal symptoms associated with smoking cessation. ( Del Core, MG; Hilleman, DE; Mohiuddin, SM; Sketch, MH, 1992)
"Clonidine was the first non-nicotine medication to show efficacy for smoking cessation in multiple studies, but its effect was found to be limited at best."2.41Advances in non-nicotine pharmacotherapy for smoking cessation. ( Adams, DP; Covey, LS; Glassman, AH; Johnston, JA; Robinson, MD; Sullivan, MA, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (77.78)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CarrĂ£o, JL1
Moreira, LB1
Fuchs, FD1
Cinciripini, PM1
Lapitsky, L1
Seay, S1
Wallfisch, A1
Meyer, WJ1
van Vunakis, H1
Hilleman, DE2
Mohiuddin, SM2
Delcore, MG1
Schneider, NG1
Olmstead, RE1
Steinberg, C1
Sloan, K1
Daims, RM1
Brown, HV1
Bevelaqua, FA1
Farid, P1
Abate, MA1
Covey, LS1
Sullivan, MA1
Johnston, JA1
Glassman, AH1
Robinson, MD1
Adams, DP1
Del Core, MG1
Sketch, MH1

Reviews

2 reviews available for buspirone and Smoking Cessation

ArticleYear
Buspirone use for smoking cessation.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:12

    Topics: Adult; Anti-Anxiety Agents; Buspirone; Clinical Trials as Topic; Female; Humans; Male; Middle Aged;

1998
Advances in non-nicotine pharmacotherapy for smoking cessation.
    Drugs, 2000, Volume: 59, Issue:1

    Topics: Antidepressive Agents; Bupropion; Buspirone; Clonidine; Humans; Moclobemide; Narcotic Antagonists; S

2000

Trials

5 trials available for buspirone and Smoking Cessation

ArticleYear
The efficacy of the combination of sertraline with buspirone for smoking cessation. A randomized clinical trial in nondepressed smokers.
    European archives of psychiatry and clinical neuroscience, 2007, Volume: 257, Issue:7

    Topics: Adolescent; Adult; Aged; Buspirone; Chi-Square Distribution; Cognitive Behavioral Therapy; Double-Bl

2007
A placebo-controlled evaluation of the effects of buspirone on smoking cessation: differences between high- and low-anxiety smokers.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Adult; Aged; Anxiety; Buspirone; Double-Blind Method; Humans; Middle Aged; Patient Compliance; Psych

1995
Comparison of fixed-dose transdermal nicotine, tapered-dose transdermal nicotine, and buspirone in smoking cessation.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:3

    Topics: Administration, Cutaneous; Adult; Behavior Therapy; Buspirone; Drug Administration Schedule; Female;

1994
Efficacy of buspirone in smoking cessation: a placebo-controlled trial.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:5

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Buspirone; Double-Blind Method; Female; Humans; Male; Middle Ag

1996
Effect of buspirone on withdrawal symptoms associated with smoking cessation.
    Archives of internal medicine, 1992, Volume: 152, Issue:2

    Topics: Adult; Buspirone; Double-Blind Method; Female; Humans; Male; Middle Aged; Smoking Cessation; Substan

1992

Other Studies

2 other studies available for buspirone and Smoking Cessation

ArticleYear
Buspirone:seven-year update.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:5

    Topics: Buspirone; Geriatrics; Humans; Mental Disorders; Primary Health Care; Smoking Cessation

1994
Possible role of buspirone hydrochloride in smoking cessation.
    Chest, 1997, Nov-05, Volume: 112, Issue:5

    Topics: Administration, Cutaneous; Buspirone; Humans; Serotonin Receptor Agonists; Smoking Cessation; Treatm

1997