buspirone has been researched along with Serotonin Syndrome in 6 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury." | 7.78 | Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012) |
| "We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury." | 3.78 | Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012) |
| "Rats treated with haloperidol at a dose of 1 mg/kg twice a day for 2 weeks displayed VCMs with twitching of facial musculature that increased in a time dependent manner as the treatment continued to 5 weeks." | 1.34 | Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats. ( Haleem, DJ; Haleem, MA; Samad, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Nunes, JC | 1 |
| Botas, JL | 1 |
| Morrison, EK | 1 |
| Rowe, AS | 1 |
| Dannawi, M | 1 |
| Jägestedt, M | 1 |
| von Bahr, C | 1 |
| Haleem, DJ | 1 |
| Samad, N | 1 |
| Haleem, MA | 1 |
| Lantz, MS | 1 |
6 other studies available for buspirone and Serotonin Syndrome
| Article | Year |
|---|---|
A Serotonin "Cocktail".
Topics: Buspirone; Citalopram; Depression; Drug Therapy, Combination; Female; Humans; Middle Aged; Selective | 2020 |
Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia.
Topics: Acetamides; Adult; Buspirone; Drug Interactions; Drug Therapy, Combination; Humans; Hypothermia; Lin | 2012 |
Possible serotonin syndrome after combination of buspirone and St John's Wort.
Topics: Adult; Agoraphobia; Buspirone; Drug Interactions; Female; Humans; Hypericum; Psychiatric Status Rati | 2002 |
[Combination of serotonergic agents resulted in severe adverse effects].
Topics: Antidepressive Agents, Second-Generation; Buspirone; Cytochrome P-450 CYP2D6; Depression; Drug Inter | 2004 |
Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Buspirone; Chromatography, Hi | 2007 |
Serotonin syndrome. A common but often unrecognized psychiatric condition.
Topics: Aged; Anxiety Disorders; Buspirone; Citalopram; Depression; Female; Humans; Selective Serotonin Reup | 2001 |