buspirone has been researched along with Retinal Degeneration in 1 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Albino rats were dosed (subcutaneously) with AL-8309A, 8-OH DPAT, or buspirone once or three times before 6-hour exposure to blue light." | 1.37 | Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress. ( Collier, RJ; Dembinska, O; Hellberg, M; Kapin, MA; Krueger, DS; Martin, EA; Patel, Y; Romano, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collier, RJ | 1 |
| Patel, Y | 1 |
| Martin, EA | 1 |
| Dembinska, O | 1 |
| Hellberg, M | 1 |
| Krueger, DS | 1 |
| Kapin, MA | 1 |
| Romano, C | 1 |
1 other study available for buspirone and Retinal Degeneration
| Article | Year |
|---|---|
Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress.
Topics: Animals; Buspirone; Dark Adaptation; Dose-Response Relationship, Drug; Electroretinography; Light; M | 2011 |