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buspirone and Retinal Degeneration

buspirone has been researched along with Retinal Degeneration in 1 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research Excerpts

ExcerptRelevanceReference
"Albino rats were dosed (subcutaneously) with AL-8309A, 8-OH DPAT, or buspirone once or three times before 6-hour exposure to blue light."1.37Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress. ( Collier, RJ; Dembinska, O; Hellberg, M; Kapin, MA; Krueger, DS; Martin, EA; Patel, Y; Romano, C, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collier, RJ1
Patel, Y1
Martin, EA1
Dembinska, O1
Hellberg, M1
Krueger, DS1
Kapin, MA1
Romano, C1

Other Studies

1 other study available for buspirone and Retinal Degeneration

ArticleYear
Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress.
    Investigative ophthalmology & visual science, 2011, Apr-04, Volume: 52, Issue:5

    Topics: Animals; Buspirone; Dark Adaptation; Dose-Response Relationship, Drug; Electroretinography; Light; M

2011