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buspirone and Respiratory Insufficiency

buspirone has been researched along with Respiratory Insufficiency in 6 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"This study details a case of Rett Syndrome where the patient's respiratory dysfunction was improved after buspirone was administered."7.73Buspirone in Rett syndrome respiratory dysfunction. ( Andaku, DK; Mercadante, MT; Schwartzman, JS, 2005)
"This study details a case of Rett Syndrome where the patient's respiratory dysfunction was improved after buspirone was administered."3.73Buspirone in Rett syndrome respiratory dysfunction. ( Andaku, DK; Mercadante, MT; Schwartzman, JS, 2005)
"buspirone or placebo."2.73The partial 5-hydroxytryptamine1A receptor agonist buspirone does not antagonize morphine-induced respiratory depression in humans. ( Geisslinger, G; Lötsch, J; Oertel, BG; Rohrbacher, M; Schmidt, H; Schneider, A; Tegeder, I, 2007)
"Ventilatory depression is a serious side-effect of opioid analgesics."1.39Effects of cholinesterase inhibitors and serotonin-1A receptor agonists on morphine-induced ventilatory depression and antinociception in rats. ( Haji, A; Kimura, S; Ohi, Y, 2013)
" Drug-related toxic signs included decreased activity and convulsions accompanied with salivation and opisthotonus in mice and rats treated with BH regardless of administration routes, and tremors and clonic convulsions accompanied with salivation in dogs treated with BH orally."1.28[Acute toxicity study of buspirone hydrochloride in mice, rats and dogs]. ( Chikazawa, H; Ishikawa, K; Kadota, T; Kai, S; Kawano, S; Kohmura, H; Kondoh, H; Kuroyanagi, K; Ohta, S; Takahashi, N, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kimura, S1
Ohi, Y1
Haji, A1
Manzke, T1
Niebert, M1
Koch, UR1
Caley, A1
Vogelgesang, S1
Bischoff, AM1
Hülsmann, S1
Ponimaskin, E1
Müller, U1
Smart, TG1
Harvey, RJ1
Richter, DW1
Andaku, DK1
Mercadante, MT1
Schwartzman, JS1
Oertel, BG1
Schneider, A1
Rohrbacher, M1
Schmidt, H1
Tegeder, I1
Geisslinger, G1
Lötsch, J1
O'Sullivan, RJ1
Brown, IG1
Pender, MP1
Kadota, T1
Kawano, S1
Chikazawa, H1
Kondoh, H1
Kuroyanagi, K1
Ohta, S1
Ishikawa, K1
Kai, S1
Kohmura, H1
Takahashi, N1

Reviews

1 review available for buspirone and Respiratory Insufficiency

ArticleYear
[Serotonin receptor 1A-modulated dephosphorylation of glycine receptor α3: a new molecular mechanism of breathing control for compensation of opioid-induced respiratory depression without loss of analgesia].
    Schmerz (Berlin, Germany), 2011, Volume: 25, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Buspirone; Cyclic AMP;

2011

Trials

1 trial available for buspirone and Respiratory Insufficiency

ArticleYear
The partial 5-hydroxytryptamine1A receptor agonist buspirone does not antagonize morphine-induced respiratory depression in humans.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:1

    Topics: Adult; Analgesics, Opioid; Buspirone; Cross-Over Studies; Dose-Response Relationship, Drug; Double-B

2007

Other Studies

4 other studies available for buspirone and Respiratory Insufficiency

ArticleYear
Effects of cholinesterase inhibitors and serotonin-1A receptor agonists on morphine-induced ventilatory depression and antinociception in rats.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Buspirone; Cholinesterase Inhibitors; Do

2013
Buspirone in Rett syndrome respiratory dysfunction.
    Brain & development, 2005, Volume: 27, Issue:6

    Topics: Adolescent; Buspirone; Female; Humans; Oxygen; Respiratory Insufficiency; Rett Syndrome; Serotonin R

2005
Apneusis responding to buspirone in multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2008, Volume: 14, Issue:5

    Topics: Adult; Buspirone; Female; Humans; Magnetic Resonance Imaging; Multiple Sclerosis, Relapsing-Remittin

2008
[Acute toxicity study of buspirone hydrochloride in mice, rats and dogs].
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 1

    Topics: Administration, Oral; Animals; Buspirone; Chemical Phenomena; Chemistry; Dogs; Female; Gastric Juice

1990