Page last updated: 2024-10-24

buspirone and Paraplegia

buspirone has been researched along with Paraplegia in 2 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guertin, PA2
Ung, RV2
Rouleau, P2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tri-therapy (SPINALON)-Elicited Spinal Locomotor Network Activation: Phase I-IIa Clinical Trial in Patients With Chronic Spinal Cord Injury[NCT01484184]Phase 1/Phase 250 participants (Actual)Interventional2013-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for buspirone and Paraplegia

ArticleYear
Oral administration of a tri-therapy for central pattern generator activation in paraplegic mice: proof-of-concept of efficacy.
    Biotechnology journal, 2010, Volume: 5, Issue:4

    Topics: Administration, Oral; Animals; Biological Clocks; Buspirone; Carbidopa; Dopamine Agents; Dose-Respon

2010
Functional and physiological effects of treadmill training induced by buspirone, carbidopa, and L-DOPA in clenbuterol-treated paraplegic mice.
    Neurorehabilitation and neural repair, 2012, Volume: 26, Issue:4

    Topics: Adipose Tissue; Analysis of Variance; Animals; Biomechanical Phenomena; Body Composition; Body Weigh

2012
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