buspirone has been researched along with Muscle Contraction in 9 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " in doses that produce apnea." | 7.70 | Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000) |
| "Thirty-six patients with generalised anxiety disorder, panic disorder or agoraphobia with panic attacks, diagnosed by DSM-III criteria, were treated with a new non-benzodiazepine anti-anxiety drug, buspirone, and with diazepam and placebo, in a cross-over design." | 5.05 | Anxiety in primary care: is short-term drug treatment appropriate? ( Owen, R; Tyrer, P, 1984) |
| " in doses that produce apnea." | 3.70 | Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. ( Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Myers, RA | 1 |
| Plym, MJ | 1 |
| Signor, LJ | 1 |
| Lodge, NJ | 1 |
| Kamikihara, SY | 2 |
| Mueller, A | 2 |
| Lima, V | 2 |
| Silva, AR | 1 |
| da Costa, IB | 1 |
| Buratini, J | 2 |
| Pupo, AS | 2 |
| Xue, L | 1 |
| Locke, GR | 1 |
| Camilleri, M | 1 |
| Schuurkes, JA | 1 |
| Meulemans, A | 1 |
| Coulie, BJ | 1 |
| Szurszewski, JH | 1 |
| Farrugia, G | 1 |
| Akinaga, J | 1 |
| Nojimoto, FD | 1 |
| Castilho, A | 1 |
| Tyrer, P | 1 |
| Owen, R | 1 |
| Hong, E | 1 |
| Castillo, C | 1 |
| Ibarra, M | 1 |
| Villalobos, R | 1 |
| Sahibzada, N | 1 |
| Ferreira, M | 1 |
| Wasserman, AM | 1 |
| Taveira-DaSilva, AM | 1 |
| Gillis, RA | 1 |
| Costall, B | 1 |
| Domeney, AM | 1 |
| Farre, AJ | 1 |
| Kelly, ME | 1 |
| Martinez, L | 1 |
| Naylor, RJ | 1 |
| Goa, KL | 1 |
| Ward, A | 1 |
1 review available for buspirone and Muscle Contraction
| Article | Year |
|---|---|
Buspirone. A preliminary review of its pharmacological properties and therapeutic efficacy as an anxiolytic.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Buspirone; Depression; Diazepam; Drug Administration | 1986 |
1 trial available for buspirone and Muscle Contraction
| Article | Year |
|---|---|
Anxiety in primary care: is short-term drug treatment appropriate?
Topics: Adult; Agoraphobia; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Female; Humans | 1984 |
7 other studies available for buspirone and Muscle Contraction
| Article | Year |
|---|---|
1-(2-pyrimidinyl)-piperazine, a buspirone metabolite, modulates bladder function in the anesthetized rat.
Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthesia; Anim | 2004 |
Differential distribution of functional alph}1-adrenergic receptor subtypes along the rat tail artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Buspirone; Conotoxins; D | 2005 |
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, S | 2006 |
alpha1-Adrenoceptors in proximal segments of tail arteries from control and reserpinised rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Arteries; Bu | 2007 |
Characterization of the alpha-adrenergic effect of some 5-HT1A agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aorta, Thoracic; Buspirone; In Vitro Techniques; Mu | 1993 |
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug I | 2000 |
Profile of action of a novel 5-hydroxytryptamine1A receptor ligand E-4424 to inhibit aversive behavior in the mouse, rat and marmoset.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Callithrix; Diazepam; Female; Guinea Pigs | 1992 |