buspirone has been researched along with Lung Neoplasms in 1 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Notably, one of these new derivatives, (E)-N-hydroxy-3-(2-oxo-1-(quinolin-2-ylmethyl)-1,2-dihydropyridin-3-yl)acrylamide (4l), significantly restored RUNX3 in a dose-dependent manner and showed high metabolic stability, a good pharmacokinetic profile with high oral bioavailability and long half-life, and strong antitumor activity." | 1.42 | Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization. ( Cho, M; Choi, S; Han, G; Jeong, JH; Kang, JS; Kim, H; Kim, HJ; Kim, JH; Lee, C; Oh, SJ; Yang, JS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, JS | 1 |
| Lee, C | 1 |
| Cho, M | 1 |
| Kim, H | 1 |
| Kim, JH | 1 |
| Choi, S | 1 |
| Oh, SJ | 1 |
| Kang, JS | 1 |
| Jeong, JH | 1 |
| Kim, HJ | 1 |
| Han, G | 1 |
1 other study available for buspirone and Lung Neoplasms
| Article | Year |
|---|---|
Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.
Topics: Acetylation; Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Core Binding Fa | 2015 |