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buspirone and Kidney Failure, Chronic

buspirone has been researched along with Kidney Failure, Chronic in 1 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" The differences between the median pharmacokinetic values of buspirone for healthy subjects, patients with mild to moderate renal impairment, and anuric patients were not statistically significant."1.27Clinical pharmacokinetics of oral buspirone in patients with impaired renal function. ( Caccia, S; Gammans, RE; Garattini, S; Mayol, RF; Mingardi, G; Pfeffer, M; Placchi, M; Vigano, GL, 1988)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caccia, S1
Vigano, GL1
Mingardi, G1
Garattini, S1
Gammans, RE1
Placchi, M1
Mayol, RF1
Pfeffer, M1

Other Studies

1 other study available for buspirone and Kidney Failure, Chronic

ArticleYear
Clinical pharmacokinetics of oral buspirone in patients with impaired renal function.
    Clinical pharmacokinetics, 1988, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Buspirone; Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Ki

1988