Page last updated: 2024-10-24

buspirone and Irritable Bowel Syndrome

buspirone has been researched along with Irritable Bowel Syndrome in 2 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.

Research Excerpts

ExcerptRelevanceReference
"Buspirone was eventually introduced."5.62Buspirone in the management of refractory irritable bowel syndrome: A case report. ( Al-Baz, N; Alabdulla, M; Haddad, PM; Karim, MA; Reagu, SM, 2021)
"Buspirone was eventually introduced."1.62Buspirone in the management of refractory irritable bowel syndrome: A case report. ( Al-Baz, N; Alabdulla, M; Haddad, PM; Karim, MA; Reagu, SM, 2021)
"Buspirone (30 mg) was used to stimulate prolactin release in 40 patients with IBS and in 40 healthy controls."1.35Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model. ( Chua, AS; Clarke, G; Dinan, TG; Keeling, PW; O'Mahony, S; Quigley, EM; Shanahan, F, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Karim, MA1
Al-Baz, N1
Haddad, PM1
Reagu, SM1
Alabdulla, M1
O'Mahony, S1
Chua, AS1
Quigley, EM1
Clarke, G1
Shanahan, F1
Keeling, PW1
Dinan, TG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Kynurenine Pathway Metabolites as Novel Translational Biological Markers of Irritable Bowel Syndrome: Relationship to Gastrointestinal Function, Cognition and Co-morbid Depression[NCT01304355]85 participants (Anticipated)Observational2011-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for buspirone and Irritable Bowel Syndrome

ArticleYear
Buspirone in the management of refractory irritable bowel syndrome: A case report.
    Medicine, 2021, Dec-23, Volume: 100, Issue:51

    Topics: Abdominal Pain; Adult; Buspirone; Humans; Irritable Bowel Syndrome; Male; Quality of Life; Serotonin

2021
Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model.
    Neurogastroenterology and motility, 2008, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Animals; Animals, Newborn; Buspirone; Disease Models, Animal; Female; Humans; Irr

2008