buspirone has been researched along with Intellectual Disability in 8 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Buspirone, a new anxiolytic agent, was used in a multiple-baseline, placebo lead-in study for the treatment of aggression and anxiety in six mentally retarded adult patients." | 9.07 | Buspirone treatment of aggression and anxiety in mentally retarded patients: a multiple-baseline, placebo lead-in study. ( Parks, A; Ratey, J; Rogentine, K; Sovner, R, 1991) |
| "We describe three patients who were given open-label buspirone for the treatment of behaviors thought to be related to anxiety." | 7.91 | Buspirone for the treatment of anxiety-related symptoms in Angelman syndrome: a case series. ( Balaj, K; Keary, CJ; McDougle, CJ; Mullett, J; Nowinski, L; Palumbo, ML; Thibert, RL; Walsh, B, 2019) |
| "To describe a case of an intellectually disabled patient who was diagnosed with autistic disorder (AD) and responded positively to buspirone, demonstrated by a reduction in target behaviors of self-injury, property destruction, and physical aggression." | 7.74 | Buspirone for autistic disorder in a woman with an intellectual disability. ( Brahm, NC; Brown, RC; Fast, GA, 2008) |
| "This case examined the efficacy of buspirone therapy as a reductive technique for severe treatment resistant paramenstrual aggression." | 7.68 | Paramenstrual aggression in mentally retarded adult ameliorated by buspirone. ( Colella, RF; Glaser, AI; Ratey, JJ, 1992) |
| "Buspirone, a new anxiolytic agent, was used in a multiple-baseline, placebo lead-in study for the treatment of aggression and anxiety in six mentally retarded adult patients." | 5.07 | Buspirone treatment of aggression and anxiety in mentally retarded patients: a multiple-baseline, placebo lead-in study. ( Parks, A; Ratey, J; Rogentine, K; Sovner, R, 1991) |
| "We describe three patients who were given open-label buspirone for the treatment of behaviors thought to be related to anxiety." | 3.91 | Buspirone for the treatment of anxiety-related symptoms in Angelman syndrome: a case series. ( Balaj, K; Keary, CJ; McDougle, CJ; Mullett, J; Nowinski, L; Palumbo, ML; Thibert, RL; Walsh, B, 2019) |
| "To describe a case of an intellectually disabled patient who was diagnosed with autistic disorder (AD) and responded positively to buspirone, demonstrated by a reduction in target behaviors of self-injury, property destruction, and physical aggression." | 3.74 | Buspirone for autistic disorder in a woman with an intellectual disability. ( Brahm, NC; Brown, RC; Fast, GA, 2008) |
| "This case examined the efficacy of buspirone therapy as a reductive technique for severe treatment resistant paramenstrual aggression." | 3.68 | Paramenstrual aggression in mentally retarded adult ameliorated by buspirone. ( Colella, RF; Glaser, AI; Ratey, JJ, 1992) |
| " The findings demonstrate that buspirone, in a daily dosage varying between 20 and 50 mg, may be effective in reducing this type of behavioural disturbance and associated with an improvement in sociability." | 1.29 | The effect of buspirone on challenging behaviour in mentally retarded patients: an open prospective multiple-case study. ( Tuinier, S; Verhoeven, WM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balaj, K | 1 |
| Nowinski, L | 1 |
| Walsh, B | 1 |
| Mullett, J | 1 |
| Palumbo, ML | 1 |
| Thibert, RL | 1 |
| McDougle, CJ | 1 |
| Keary, CJ | 1 |
| Helvink, B | 1 |
| Holroyd, S | 1 |
| Brahm, NC | 1 |
| Fast, GA | 1 |
| Brown, RC | 1 |
| Verhoeven, WM | 1 |
| Tuinier, S | 1 |
| Colella, RF | 1 |
| Ratey, JJ | 2 |
| Glaser, AI | 1 |
| Gedye, A | 1 |
| Ratey, J | 1 |
| Sovner, R | 2 |
| Parks, A | 1 |
| Rogentine, K | 1 |
| Mikkelsen, E | 1 |
| Chmielinski, HE | 1 |
2 trials available for buspirone and Intellectual Disability
| Article | Year |
|---|---|
Buspirone alone or with serotonergic diet reduced aggression in a developmentally disabled adult.
Topics: Adult; Aggression; Buspirone; Combined Modality Therapy; Female; Humans; Intellectual Disability; Se | 1991 |
Buspirone treatment of aggression and anxiety in mentally retarded patients: a multiple-baseline, placebo lead-in study.
Topics: Adult; Aggression; Anxiety Disorders; Buspirone; Dose-Response Relationship, Drug; Female; Humans; I | 1991 |
6 other studies available for buspirone and Intellectual Disability
| Article | Year |
|---|---|
Buspirone for the treatment of anxiety-related symptoms in Angelman syndrome: a case series.
Topics: Adult; Angelman Syndrome; Anxiety; Anxiety Disorders; Buspirone; Female; Humans; Intellectual Disabi | 2019 |
Buspirone for stereotypic movements in elderly with cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Buspirone; Dose-Response Relationsh | 2006 |
Buspirone for autistic disorder in a woman with an intellectual disability.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Autistic Disorder; Buspirone; Epilepsy | 2008 |
The effect of buspirone on challenging behaviour in mentally retarded patients: an open prospective multiple-case study.
Topics: Adult; Aggression; Arousal; Buspirone; Dose-Response Relationship, Drug; Drug Administration Schedul | 1996 |
Paramenstrual aggression in mentally retarded adult ameliorated by buspirone.
Topics: Adaptation, Psychological; Adult; Aggression; Behavior Therapy; Buspirone; Female; Humans; Instituti | 1992 |
Buspirone therapy for maladaptive behavior and anxiety in developmentally disabled persons.
Topics: Adjustment Disorders; Adult; Aggression; Anxiety Disorders; Buspirone; Female; Humans; Intellectual | 1989 |