buspirone has been researched along with Innate Inflammatory Response in 10 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the influence of inflammatory pain and/or stress of isolation from the mother in newborn female rats to pain sensitivity when they reached adulthood; an attempt was undertaken to correct identified deviations using 5-HT1A-receptor agonist buspirone." | 7.83 | [THE DAMAGING EFFECTS AT AN EARLY AGE ALTER PAIN SENSITIVITY IN ADULT FEMALE RATS, CORRECTION WITH BUSPIRONE]. ( Butkevich, IP; Mikhailenko, VA, 2016) |
| "We studied the effects of injections of 5-HT1A-agonist buspirone to pregnant rats before stress exposure on corticosterone level in the dynamics of stress response to inflammatory-induced pain in 7-day-old offspring." | 7.79 | Tonic pain response during inflammation and stress-induced corticosterone variations in prenatally stressed infant rats: effects of maternal buspirone injected during pregnancy. ( Bagaeva, TR; Butkevich, IP; Makukhina, GV; Mikhailenko, VA; Stolyarova, YA, 2013) |
| "Colitis was induced by intrarectal instillation of TNBS in all research groups except the control group, and rats were meliorated with dexamethasone and buspirone." | 5.72 | Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway. ( Abdollahi, A; Chaboki, A; Dehpour, AR; Hamaneh, AM; Mohammadi, S; Rashidian, A; Shayan, M; Sheibani, M; Yousefi-Manesh, H, 2022) |
| "Buspirone was injected to female rats from the 9th to 21st days of pregnancy; during the last week of pregnancy buspirone was injected 10 min before immobilization stress." | 5.36 | [Effects of prenatal influences of buspirone and stress on indices of inflammatory pain response and depressive behaviour in adult rats]. ( Butkevich, IP; Mikhaĭlenko, VA; Otellin, VA; Semenov, PO; Vershinina, EA, 2010) |
| " In the present study, we investigated the influence of inflammatory pain and/or stress of isolation from the mother in newborn female rats to pain sensitivity when they reached adulthood; an attempt was undertaken to correct identified deviations using 5-HT1A-receptor agonist buspirone." | 3.83 | [THE DAMAGING EFFECTS AT AN EARLY AGE ALTER PAIN SENSITIVITY IN ADULT FEMALE RATS, CORRECTION WITH BUSPIRONE]. ( Butkevich, IP; Mikhailenko, VA, 2016) |
| "We studied the effects of injections of 5-HT1A-agonist buspirone to pregnant rats before stress exposure on corticosterone level in the dynamics of stress response to inflammatory-induced pain in 7-day-old offspring." | 3.79 | Tonic pain response during inflammation and stress-induced corticosterone variations in prenatally stressed infant rats: effects of maternal buspirone injected during pregnancy. ( Bagaeva, TR; Butkevich, IP; Makukhina, GV; Mikhailenko, VA; Stolyarova, YA, 2013) |
| "In the nociception test, the pain-induced functional impairment rat model, uric acid at 3." | 3.73 | Influence of inflammatory nociception on the anxiolytic-like effect of diazepam and buspirone in rats. ( Fernández-Guasti, A; López-Muñoz, FJ; Martínez-Mota, L; Reyes, R, 2005) |
| "Colitis was induced by intrarectal instillation of TNBS in all research groups except the control group, and rats were meliorated with dexamethasone and buspirone." | 1.72 | Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway. ( Abdollahi, A; Chaboki, A; Dehpour, AR; Hamaneh, AM; Mohammadi, S; Rashidian, A; Shayan, M; Sheibani, M; Yousefi-Manesh, H, 2022) |
| "Buspirone is an anxiolytic drug with robust serotonin receptor 1A (Htr1a) agonist activities." | 1.62 | Assessing the Anti-Inflammatory Activity of the Anxiolytic Drug Buspirone Using CRISPR-Cas9 Gene Editing in LPS-Stimulated BV-2 Microglial Cells. ( Al-Badri, G; Castorina, A; Faiz, A; Fisher, T; Keay, KA; Musumeci, G; Thomas Broome, S, 2021) |
| " We recently showed that maternal buspirone, a 5-HT1A receptor agonist, protects against the adverse effects of in utero stress on depression and pain in adult rat offspring." | 1.37 | Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences. ( Aloisi, AM; Butkevich, IP; Mikhailenko, VA; Otellin, VA; Vershinina, EA, 2011) |
| "Buspirone was injected to female rats from the 9th to 21st days of pregnancy; during the last week of pregnancy buspirone was injected 10 min before immobilization stress." | 1.36 | [Effects of prenatal influences of buspirone and stress on indices of inflammatory pain response and depressive behaviour in adult rats]. ( Butkevich, IP; Mikhaĭlenko, VA; Otellin, VA; Semenov, PO; Vershinina, EA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rashidian, A | 1 |
| Mohammadi, S | 1 |
| Hamaneh, AM | 1 |
| Chaboki, A | 1 |
| Shayan, M | 1 |
| Sheibani, M | 1 |
| Abdollahi, A | 1 |
| Yousefi-Manesh, H | 1 |
| Dehpour, AR | 1 |
| Butkevich, IP | 7 |
| Mikhailenko, VA | 7 |
| Thomas Broome, S | 1 |
| Fisher, T | 1 |
| Faiz, A | 1 |
| Keay, KA | 1 |
| Musumeci, G | 1 |
| Al-Badri, G | 1 |
| Castorina, A | 1 |
| Vershinina, EA | 4 |
| Astapova, MK | 1 |
| Bagaeva, TR | 2 |
| Aloisi, AM | 2 |
| Otellin, VA | 3 |
| Makukhina, GV | 1 |
| Stolyarova, YA | 1 |
| Semenov, PO | 1 |
| Fernández-Guasti, A | 1 |
| Reyes, R | 1 |
| Martínez-Mota, L | 1 |
| López-Muñoz, FJ | 1 |
10 other studies available for buspirone and Innate Inflammatory Response
| Article | Year |
|---|---|
Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway.
Topics: Animals; Anti-Inflammatory Agents; Buspirone; Colitis; Colon; Dexamethasone; Disease Models, Animal; | 2022 |
Effects of Stress Exposure during Adolescent Period on Inflammatory Pain Response, Psychoemotional Behavior, and Action of Antidepressants in Prenatally Stressed Adult Male Rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Buspirone; Female; Fluoxetine; Inflammation; Male; | 2020 |
Assessing the Anti-Inflammatory Activity of the Anxiolytic Drug Buspirone Using CRISPR-Cas9 Gene Editing in LPS-Stimulated BV-2 Microglial Cells.
Topics: Animals; Anti-Inflammatory Agents; Buspirone; Cell Line; Inflammation; Mice; Microglia; Receptor, Se | 2021 |
[INVOLVEMENT OF 5-HT1A RECEPTORS IN LONG-TERM INFLUENCE OF INFLAMMATORY PAIN AND STRESS IN EARLY AGE ON REACTIVITY OF NOCICEPTIVE SYSTEM].
Topics: Animals; Animals, Newborn; Buspirone; Inflammation; Nociception; Pain; Rats; Rats, Wistar; Receptors | 2016 |
[THE DAMAGING EFFECTS AT AN EARLY AGE ALTER PAIN SENSITIVITY IN ADULT FEMALE RATS, CORRECTION WITH BUSPIRONE].
Topics: Animals; Animals, Newborn; Buspirone; Female; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, Wi | 2016 |
Inflammatory pain and corticosterone response in infant rats: effect of 5-HT1A agonist buspirone prior to gestational stress.
Topics: Animals; Animals, Newborn; Buspirone; Corticosterone; Female; Hypothalamo-Hypophyseal System; Inflam | 2013 |
Tonic pain response during inflammation and stress-induced corticosterone variations in prenatally stressed infant rats: effects of maternal buspirone injected during pregnancy.
Topics: Animals; Behavior, Animal; Buspirone; Corticosterone; Female; Inflammation; Nociceptors; Pain; Pain | 2013 |
[Effects of prenatal influences of buspirone and stress on indices of inflammatory pain response and depressive behaviour in adult rats].
Topics: Animals; Behavior, Animal; Buspirone; Depression; Female; Immobilization; Inflammation; Male; Pain; | 2010 |
Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences.
Topics: Aging; Animals; Animals, Newborn; Buspirone; Chronic Pain; Depressive Disorder; Female; Inflammation | 2011 |
Influence of inflammatory nociception on the anxiolytic-like effect of diazepam and buspirone in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Buspirone; D | 2005 |