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buspirone and Hypothermia, Accidental

buspirone has been researched along with Hypothermia, Accidental in 10 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Research Excerpts

ExcerptRelevanceReference
"We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury."7.78Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012)
"We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury."3.78Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012)
"Intraperitoneal administration of the serotonin 5-HT1A agonist, buspirone (1-5 mg/kg), produced dose- and time-related core hypothermia that was coincident with analgesia against a thermally noxious stimulus."3.68Putative mechanisms of buspirone-induced antinociception in the rat. ( Giordano, J; Rogers, L, 1992)
" In addition, chronic administration of anxiolytics and neuroleptics was also effective in this respect."1.28Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants. ( Heal, DJ; Hearson, M; Martin, KF; Phillips, I; Prow, MR, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lenhardt, R1
Orhan-Sungur, M1
Komatsu, R1
Govinda, R1
Kasuya, Y1
Sessler, DI1
Wadhwa, A1
Morrison, EK1
Rowe, AS1
Pretorius, T1
Bristow, GK1
Steinman, AM1
Giesbrecht, GG1
Navinés, R2
Gómez-Gil, E2
Martín-Santos, R2
Martínez de Osaba, MJ2
Imaz, ML2
Gastó, C2
Cowen, PJ1
Power, AC1
Ware, CJ1
Anderson, IM1
Blier, P1
Seletti, B1
Gilbert, F1
Young, SN1
Benkelfat, C1
Martin, KF1
Phillips, I1
Hearson, M1
Prow, MR1
Heal, DJ1
Giordano, J1
Rogers, L1
Komissarov, IV1
Dolzhenko, AT1
Obraztsova, OG1
Zin'kovskaia, LIa1

Trials

2 trials available for buspirone and Hypothermia, Accidental

ArticleYear
Suppression of shivering during hypothermia using a novel drug combination in healthy volunteers.
    Anesthesiology, 2009, Volume: 111, Issue:1

    Topics: Adolescent; Adult; Body Temperature; Buspirone; Dexmedetomidine; Drug Synergism; Drug Therapy, Combi

2009
Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response.
    Psychoneuroendocrinology, 2007, Volume: 32, Issue:4

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-G

2007

Other Studies

8 other studies available for buspirone and Hypothermia, Accidental

ArticleYear
Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:5

    Topics: Acetamides; Adult; Buspirone; Drug Interactions; Drug Therapy, Combination; Humans; Hypothermia; Lin

2012
Thermal effects of whole head submersion in cold water on nonshivering humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Body Temperature; Body Temperature Regulation; Buspirone; Cold Temperatu

2006
An increased hypothermic response to buspirone in patients with major depression.
    Psychopharmacology, 2006, Volume: 188, Issue:2

    Topics: Adult; Buspirone; Case-Control Studies; Cross-Sectional Studies; Depressive Disorder, Major; Female;

2006
5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Autoreceptors; Buspirone; Depressive Disorder;

1994
Serotonin 1A receptor activation and hypothermia in humans: lack of evidence for a presynaptic mediation.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:2

    Topics: Adult; Autoreceptors; Body Temperature; Brain; Buspirone; Cross-Over Studies; Double-Blind Method; G

2002
Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Body Temperature; Buspirone;

1992
Putative mechanisms of buspirone-induced antinociception in the rat.
    Pain, 1992, Volume: 50, Issue:3

    Topics: Adrenalectomy; Aminoglutethimide; Analgesics; Animals; Benzylamines; Buspirone; Dose-Response Relati

1992
[An analysis of the hypothermic action of 8-hydroxy-2-(di-N-propylamino)tetralin, 1-(2-pyrimidinyl)piperazine and its derivatives].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 109, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Buspirone; Dose-Response Relation

1990