buspirone has been researched along with Hypothermia, Accidental in 10 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury." | 7.78 | Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012) |
| "We present a case of a 28-year-old man who potentially developed serotonin syndrome after coadministration of buspirone and linezolid while being therapeutically cooled for traumatic brain injury." | 3.78 | Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia. ( Morrison, EK; Rowe, AS, 2012) |
| "Intraperitoneal administration of the serotonin 5-HT1A agonist, buspirone (1-5 mg/kg), produced dose- and time-related core hypothermia that was coincident with analgesia against a thermally noxious stimulus." | 3.68 | Putative mechanisms of buspirone-induced antinociception in the rat. ( Giordano, J; Rogers, L, 1992) |
| " In addition, chronic administration of anxiolytics and neuroleptics was also effective in this respect." | 1.28 | Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants. ( Heal, DJ; Hearson, M; Martin, KF; Phillips, I; Prow, MR, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lenhardt, R | 1 |
| Orhan-Sungur, M | 1 |
| Komatsu, R | 1 |
| Govinda, R | 1 |
| Kasuya, Y | 1 |
| Sessler, DI | 1 |
| Wadhwa, A | 1 |
| Morrison, EK | 1 |
| Rowe, AS | 1 |
| Pretorius, T | 1 |
| Bristow, GK | 1 |
| Steinman, AM | 1 |
| Giesbrecht, GG | 1 |
| Navinés, R | 2 |
| Gómez-Gil, E | 2 |
| Martín-Santos, R | 2 |
| Martínez de Osaba, MJ | 2 |
| Imaz, ML | 2 |
| Gastó, C | 2 |
| Cowen, PJ | 1 |
| Power, AC | 1 |
| Ware, CJ | 1 |
| Anderson, IM | 1 |
| Blier, P | 1 |
| Seletti, B | 1 |
| Gilbert, F | 1 |
| Young, SN | 1 |
| Benkelfat, C | 1 |
| Martin, KF | 1 |
| Phillips, I | 1 |
| Hearson, M | 1 |
| Prow, MR | 1 |
| Heal, DJ | 1 |
| Giordano, J | 1 |
| Rogers, L | 1 |
| Komissarov, IV | 1 |
| Dolzhenko, AT | 1 |
| Obraztsova, OG | 1 |
| Zin'kovskaia, LIa | 1 |
2 trials available for buspirone and Hypothermia, Accidental
| Article | Year |
|---|---|
Suppression of shivering during hypothermia using a novel drug combination in healthy volunteers.
Topics: Adolescent; Adult; Body Temperature; Buspirone; Dexmedetomidine; Drug Synergism; Drug Therapy, Combi | 2009 |
Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-G | 2007 |
8 other studies available for buspirone and Hypothermia, Accidental
| Article | Year |
|---|---|
Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia.
Topics: Acetamides; Adult; Buspirone; Drug Interactions; Drug Therapy, Combination; Humans; Hypothermia; Lin | 2012 |
Thermal effects of whole head submersion in cold water on nonshivering humans.
Topics: Adult; Anti-Anxiety Agents; Body Temperature; Body Temperature Regulation; Buspirone; Cold Temperatu | 2006 |
An increased hypothermic response to buspirone in patients with major depression.
Topics: Adult; Buspirone; Case-Control Studies; Cross-Sectional Studies; Depressive Disorder, Major; Female; | 2006 |
5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Autoreceptors; Buspirone; Depressive Disorder; | 1994 |
Serotonin 1A receptor activation and hypothermia in humans: lack of evidence for a presynaptic mediation.
Topics: Adult; Autoreceptors; Body Temperature; Brain; Buspirone; Cross-Over Studies; Double-Blind Method; G | 2002 |
Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Body Temperature; Buspirone; | 1992 |
Putative mechanisms of buspirone-induced antinociception in the rat.
Topics: Adrenalectomy; Aminoglutethimide; Analgesics; Animals; Benzylamines; Buspirone; Dose-Response Relati | 1992 |
[An analysis of the hypothermic action of 8-hydroxy-2-(di-N-propylamino)tetralin, 1-(2-pyrimidinyl)piperazine and its derivatives].
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Buspirone; Dose-Response Relation | 1990 |