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buspirone and Dyskinesia, Medication-Induced

buspirone has been researched along with Dyskinesia, Medication-Induced in 30 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Research Excerpts

ExcerptRelevanceReference
"Prolactin response to buspirone was evaluated in patients with schizophrenia, with and without tardive dyskinesia (TD)."7.73Tardive dyskinesia predicts prolactin response to buspirone challenge in people with schizophrenia. ( Conley, RR; Kelly, DL; Kim, YH; Lee, JG; Shim, JC, 2005)
"Pronounced oral dyskinesia developed in an elderly woman with advanced dementia who had been treated with buspirone for 3 days."4.77Oral dyskinesia associated with buspirone use in an elderly woman. ( Strauss, A, 1988)
"Prolactin response to buspirone was evaluated in patients with schizophrenia, with and without tardive dyskinesia (TD)."3.73Tardive dyskinesia predicts prolactin response to buspirone challenge in people with schizophrenia. ( Conley, RR; Kelly, DL; Kim, YH; Lee, JG; Shim, JC, 2005)
"Buspirone is a novel anxiolytic chemically unrelated to the benzodiazepines."2.66Buspirone in the treatment of tardive dyskinesia. ( Ross, CA, 1987)
"Buspirone is an anxiolytic drug and is a partial agonist for the serotonin 5-HT(1A) receptors as well as possessing low affinity and is an antagonist for the dopamine D(2) autoreceptors, with some evidence of a weak affinity to 5-HT(2) receptors."2.48Buspirone: what is it all about? ( Loane, C; Politis, M, 2012)
"The results suggest that compounds that indirectly facilitate 5-HT1 A receptor activation, such as citalopram, may be more effective therapeutics than direct 5-HT1 A receptor agonists because they exhibit similar anti-dyskinesia efficacy, while possessing a reduced side effect profile."1.42Side effect profile of 5-HT treatments for Parkinson's disease and L-DOPA-induced dyskinesia in rats. ( Bishop, C; Conti, MM; Lindenbach, D; Ostock, CY; Palumbo, N; Vilceus, N, 2015)
"In quinelorane-treated wild-type mice flibanserin as well as buspirone significantly reduced dystonia (p < 0."1.38The 5-HT1A-receptor agonist flibanserin reduces drug-induced dyskinesia in RGS9-deficient mice. ( Adamaszek, M; Beck, J; Ohm, S; Schwarz, J; Strecker, K; Wegner, F, 2012)
"Rats treated with haloperidol at a dose of 1 mg/kg exhibited impaired motor coordination and a decrease in exploratory activity."1.34Reversal of haloperidol-induced extrapyramidal symptoms by buspirone: a time-related study. ( Haleem, DJ; Haleem, MA; Samad, N, 2007)
"Rats treated with haloperidol at a dose of 1 mg/kg twice a day for 2 weeks displayed VCMs with twitching of facial musculature that increased in a time dependent manner as the treatment continued to 5 weeks."1.34Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats. ( Haleem, DJ; Haleem, MA; Samad, N, 2007)
" One patient developed a lasting problem of cervical-cranial dystonia and tremors after treatment with buspirone at a dosage of 40 mg/day for several weeks."1.29Persistent movement disorders induced by buspirone. ( Hening, W; LeWitt, PA; McHale, D; Walters, A, 1993)
"Buspirone was well tolerated by most subjects."1.29Buspirone in the treatment of tardive dyskinesia. ( Drevets, WC; Moss, LE; Neppe, VM, 1993)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.67)18.7374
1990's7 (23.33)18.2507
2000's7 (23.33)29.6817
2010's10 (33.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Thomsen, M1
Stoica, A1
Christensen, KV1
Fryland, T1
Mikkelsen, JD1
Hansen, JB1
Shin, E2
Lisci, C1
Tronci, E1
Fidalgo, C1
Stancampiano, R1
Björklund, A2
Carta, M3
Azkona, G1
Sagarduy, A2
Aristieta, A1
Vazquez, N1
Zubillaga, V1
Ruíz-Ortega, JA2
Pérez-Navarro, E1
Ugedo, L2
Sánchez-Pernaute, R1
Politis, M2
Wu, K1
Loane, C2
Brooks, DJ1
Kiferle, L1
Turkheimer, FE1
Bain, P1
Molloy, S1
Piccini, P1
Lindenbach, D1
Palumbo, N1
Ostock, CY1
Vilceus, N1
Conti, MM1
Bishop, C1
Levin, OS1
Llorente, J1
Miguelez, C1
Morera-Herreras, T1
Paquette, MA1
Foley, K1
Brudney, EG1
Meshul, CK1
Johnson, SW1
Berger, SP1
Howland, RH1
Strecker, K1
Adamaszek, M1
Ohm, S1
Wegner, F1
Beck, J1
Schwarz, J1
Garcia, J1
Winkler, C1
Pavlovic, ZM1
Lundblad, M1
Usiello, A1
Håkansson, K1
Fisone, G1
Cenci, MA1
Shim, JC1
Kim, YH1
Kelly, DL1
Lee, JG1
Conley, RR1
Haleem, DJ2
Samad, N2
Haleem, MA2
LeWitt, PA1
Walters, A1
Hening, W1
McHale, D1
Moss, LE1
Neppe, VM2
Drevets, WC1
Bonifati, V1
Fabrizio, E1
Cipriani, R1
Vanacore, N1
Meco, G1
Queiroz, CM2
Frussa-Filho, R2
Alcântara, FB1
Yagüe, AM1
Bibancos, T1
Brody, D1
Adler, LA1
Kim, T1
Angrist, B1
Rotrosen, J1
Kleedorfer, B1
Lees, AJ1
Stern, GM1
Rock, NL1
Lydiard, RB1
Ross, CA1
Strauss, A1
Simpson, GM1
Singh, H1

Reviews

2 reviews available for buspirone and Dyskinesia, Medication-Induced

ArticleYear
Buspirone: what is it all about?
    Brain research, 2012, Jun-21, Volume: 1461

    Topics: Animals; Buspirone; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Humans; Mental Disor

2012
Oral dyskinesia associated with buspirone use in an elderly woman.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:8

    Topics: Aged; Aged, 80 and over; Buspirone; Dementia; Dyskinesia, Drug-Induced; Female; Humans; Mouth Diseas

1988

Trials

3 trials available for buspirone and Dyskinesia, Medication-Induced

ArticleYear
Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:3

    Topics: Aged; Antiparkinson Agents; Buspirone; Case-Control Studies; Dopamine; Double-Blind Method; Dyskines

2014
Buspirone in levodopa-induced dyskinesias.
    Clinical neuropharmacology, 1994, Volume: 17, Issue:1

    Topics: Aged; Buspirone; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Midd

1994
Buspirone in the treatment of tardive dyskinesia.
    Medical hypotheses, 1987, Volume: 22, Issue:3

    Topics: Anti-Anxiety Agents; Buspirone; Clinical Trials as Topic; Dopamine; Dyskinesia, Drug-Induced; Humans

1987

Other Studies

25 other studies available for buspirone and Dyskinesia, Medication-Induced

ArticleYear
Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats.
    Experimental neurology, 2022, Volume: 358

    Topics: Amantadine; Animals; Antiparkinson Agents; Buspirone; Dyskinesia, Drug-Induced; Levodopa; Oxazolidin

2022
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
    Neurobiology of disease, 2014, Volume: 62

    Topics: Amphetamine; Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Benzazepines; Buspirone; Disease

2014
Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in L-DOPA-treated rats.
    Neuropharmacology, 2014, Volume: 79

    Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Buspirone; Corpus Striatum; Cyclic AMP Respon

2014
Side effect profile of 5-HT treatments for Parkinson's disease and L-DOPA-induced dyskinesia in rats.
    British journal of pharmacology, 2015, Volume: 172, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiparkinson Agents; Buspirone; Citalopram; Dyskin

2015
[The use of buspirone in clinical practice].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:4

    Topics: Anti-Anxiety Agents; Anxiety; Buspirone; Depression; Dyskinesia, Drug-Induced; Humans; Parkinson Dis

2015
Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors.
    Experimental neurology, 2016, Volume: 277

    Topics: Action Potentials; Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Buspirone; Desipramine;

2016
The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism.
    Psychopharmacology, 2009, Volume: 204, Issue:4

    Topics: Animals; Buspirone; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Dyski

2009
Drug therapies for tardive dyskinesia: Part 1.
    Journal of psychosocial nursing and mental health services, 2011, Volume: 49, Issue:6

    Topics: Amantadine; Antipsychotic Agents; Buspirone; Dopamine Agents; Dyskinesia, Drug-Induced; Humans; Move

2011
The 5-HT1A-receptor agonist flibanserin reduces drug-induced dyskinesia in RGS9-deficient mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:11

    Topics: Animals; Benzimidazoles; Buspirone; Dose-Response Relationship, Drug; Drug Administration Schedule;

2012
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
    Neurobiology of disease, 2012, Volume: 47, Issue:3

    Topics: 5,6-Dihydroxytryptamine; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antiparkinso

2012
Buspirone to improve compliance in venlafaxine-induced movement disorder.
    The international journal of neuropsychopharmacology, 2004, Volume: 7, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Buspirone; Compliance; Cyclohexanols; Depressive Disorder,

2004
Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
    Experimental neurology, 2005, Volume: 194, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Adrenergic Agents; Amantadine; Animals; Antiparkinson Agents; Basal

2005
Tardive dyskinesia predicts prolactin response to buspirone challenge in people with schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2005,Spring, Volume: 17, Issue:2

    Topics: Adult; Antipsychotic Agents; Buspirone; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced;

2005
Reversal of haloperidol-induced extrapyramidal symptoms by buspirone: a time-related study.
    Behavioural pharmacology, 2007, Volume: 18, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Ataxia; Buspirone; Catalepsy; Dyskinesia, Drug-I

2007
Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Buspirone; Chromatography, Hi

2007
Persistent movement disorders induced by buspirone.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:3

    Topics: Antipsychotic Agents; Buspirone; Dyskinesia, Drug-Induced; Dystonia; Humans; Male; Middle Aged; Phon

1993
Buspirone in the treatment of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Buspirone; Dose-Response Relationship, Drug; Dyskinesia, Drug-Ind

1993
Effects of buspirone on an animal model of tardive dyskinesia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1999, Volume: 23, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Animals; Buspirone; Disease Models, Animal; Dopamine; Dyskinesia, Drug

1999
Acute buspirone abolishes the expression of behavioral dopaminergic supersensitivity in mice.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Dopamine; Dopamine Antagonists; Drug Hype

2002
Effects of buspirone in seven schizophrenic subjects.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:1

    Topics: Antipsychotic Agents; Buspirone; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Psychi

1990
Buspirone in the treatment of levodopa induced dyskinesias.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:4

    Topics: Adult; Aged; Apomorphine; Buspirone; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Hu

1991
Possible adverse effects of buspirone when used with other psychotropic drugs.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Adult; Akathisia, Drug-Induced; Bipolar Disorder; Buspirone; Dose-Response Relationship, Drug; Drug

1990
Buspirone revisited.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:8

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Buspirone; Dyskinesia, Drug-Induced; Female; Humans;

1989
High-dose buspirone in case of tardive dyskinesia.
    Lancet (London, England), 1989, Dec-16, Volume: 2, Issue:8677

    Topics: Buspirone; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged; Nadolol

1989
Buspirone and dyskinesia.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:12

    Topics: Aged; Buspirone; Dyskinesia, Drug-Induced; Female; Humans; Research Design

1988