buspirone has been researched along with Disease Models, Animal in 77 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asenapine may have superior therapeutic effect on anxiety symptoms than other agents, although the underlying mechanism of its anxiolytic activity remains unknown." | 7.83 | Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model. ( Imanishi, T; Kondo, M; Koyama, T; Ohyama, M; Yamauchi, M, 2016) |
| "Buspirone, a 5-HT1A agonist, has been shown to decrease the intake of ethanol when given as a single dose to rats with a psychological dependence induced according to our rat model of alcoholism." | 7.70 | Acute and long term effects of buspirone treatments on voluntary ethanol intake in a rat model of alcoholism. ( Hedlund, L; Wahlström, G, 1999) |
| "Colitis was induced by intrarectal instillation of TNBS in all research groups except the control group, and rats were meliorated with dexamethasone and buspirone." | 5.72 | Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway. ( Abdollahi, A; Chaboki, A; Dehpour, AR; Hamaneh, AM; Mohammadi, S; Rashidian, A; Shayan, M; Sheibani, M; Yousefi-Manesh, H, 2022) |
| "Asenapine may have superior therapeutic effect on anxiety symptoms than other agents, although the underlying mechanism of its anxiolytic activity remains unknown." | 3.83 | Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model. ( Imanishi, T; Kondo, M; Koyama, T; Ohyama, M; Yamauchi, M, 2016) |
| " The present study examined the effect of concurrent administration of the anxiolytic serotonin 5-HT(1A) receptor partial agonist buspirone on anxiety-induced facilitation of habit memory." | 3.78 | Buspirone blocks the enhancing effect of the anxiogenic drug RS 79948-197 on consolidation of habit memory. ( Goodman, J; Leong, KC; Packard, MG, 2012) |
| "Buspirone, a 5-HT1A agonist, has been shown to decrease the intake of ethanol when given as a single dose to rats with a psychological dependence induced according to our rat model of alcoholism." | 3.70 | Acute and long term effects of buspirone treatments on voluntary ethanol intake in a rat model of alcoholism. ( Hedlund, L; Wahlström, G, 1999) |
| "Buspirone treatment also improved mitochondrial function and antioxidant activities." | 1.72 | The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease. ( Castorina, A; Thomas Broome, S, 2022) |
| "Colitis was induced by intrarectal instillation of TNBS in all research groups except the control group, and rats were meliorated with dexamethasone and buspirone." | 1.72 | Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway. ( Abdollahi, A; Chaboki, A; Dehpour, AR; Hamaneh, AM; Mohammadi, S; Rashidian, A; Shayan, M; Sheibani, M; Yousefi-Manesh, H, 2022) |
| "Buspirone is an effective anxiolytic drug in humans, which has been found, with acute administration, to reduce this anxiety-like response in zebrafish." | 1.62 | Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish. ( Hawkey, AB; Hoeng, J; Koshibu, K; Levin, ED; Peitsch, MC, 2021) |
| " Addiction and hyperalgesia associated with their long-term use limits the clinical utility of these drugs." | 1.46 | Inhibition of Reinforcing, Hyperalgesic, and Motor Effects of Morphine by Buspirone in Rats. ( Haleem, DJ; Nawaz, S, 2017) |
| "A single injected dose of the antidepressant fluoxetine had no significant effect on animals' activity in the open-arm test, neither in a small dosage (5 mg/kgbw) nor in a higher one (10 mg/kgbw), whereas a single high dose of buspirone significantly impeded the open-arm activity of the rats." | 1.40 | Dose dependent effects of serotonergic agents on anxiety. ( Dogaru, MT; Gáll, Z; Kolcsar, M, 2014) |
| "Spinocerebellar ataxias are autosomal dominant diseases, associated in some types with a CAG repeat expansion, and characterised by a progressive loss of motor function." | 1.39 | Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1. ( Nag, N; Storey, E; Tarlac, V, 2013) |
| "Buspirone is a partial agonist of 5-HT(1A) receptors and is used in the treatment of depression and anxiety." | 1.36 | Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study. ( Diksic, M; Sato, H; Skelin, I, 2010) |
| "Buspirone (30 mg) was used to stimulate prolactin release in 40 patients with IBS and in 40 healthy controls." | 1.35 | Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model. ( Chua, AS; Clarke, G; Dinan, TG; Keeling, PW; O'Mahony, S; Quigley, EM; Shanahan, F, 2008) |
| "Pretreatment with buspirone (1." | 1.33 | Buspirone attenuates conditioned fear-induced c-Fos expression in the rat hippocampus. ( Bidziński, A; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Szyndler, J; Taracha, E; Wisłowska-Stanek, A; Zienowicz, M, 2005) |
| "Pretreatment with buspirone (0." | 1.30 | Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test. ( Bourin, M; Redrobe, JP, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.49) | 18.7374 |
| 1990's | 15 (19.48) | 18.2507 |
| 2000's | 21 (27.27) | 29.6817 |
| 2010's | 29 (37.66) | 24.3611 |
| 2020's | 7 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Thomas Broome, S | 1 |
| Castorina, A | 1 |
| Rashidian, A | 1 |
| Mohammadi, S | 1 |
| Hamaneh, AM | 1 |
| Chaboki, A | 1 |
| Shayan, M | 1 |
| Sheibani, M | 1 |
| Abdollahi, A | 1 |
| Yousefi-Manesh, H | 1 |
| Dehpour, AR | 1 |
| Higuchi, Y | 1 |
| Tada, T | 1 |
| Nakachi, T | 1 |
| Arakawa, H | 1 |
| Partridge, KJ | 1 |
| Olson, R | 1 |
| Hillhouse, TM | 1 |
| Tsagkaris, C | 1 |
| Papakosta, V | 1 |
| Miranda, AV | 1 |
| Zacharopoulou, L | 1 |
| Danilchenko, V | 1 |
| Matiashova, L | 1 |
| Dhar, A | 1 |
| Hawkey, AB | 1 |
| Hoeng, J | 1 |
| Peitsch, MC | 1 |
| Levin, ED | 3 |
| Koshibu, K | 1 |
| Lyubashina, OA | 1 |
| Busygina, II | 1 |
| Panteleev, SS | 1 |
| Nozdrachev, AD | 1 |
| Di Ciano, P | 1 |
| Cormick, PM | 1 |
| Stefan, C | 1 |
| Wong, E | 1 |
| Kim, A | 1 |
| Remington, G | 1 |
| Le Foll, B | 1 |
| Baggio, S | 1 |
| Mussulini, BH | 1 |
| de Oliveira, DL | 1 |
| Gerlai, R | 1 |
| Rico, EP | 1 |
| Collins, GT | 1 |
| France, CP | 1 |
| Maximino, C | 1 |
| Puty, B | 1 |
| Benzecry, R | 1 |
| Araújo, J | 1 |
| Lima, MG | 1 |
| de Jesus Oliveira Batista, E | 1 |
| Renata de Matos Oliveira, K | 1 |
| Crespo-Lopez, ME | 1 |
| Herculano, AM | 1 |
| Horváth, J | 1 |
| Szögi, T | 1 |
| Müller, G | 1 |
| Szegedi, V | 1 |
| Miyazaki, I | 1 |
| Asanuma, M | 1 |
| Murakami, S | 1 |
| Takeshima, M | 1 |
| Torigoe, N | 1 |
| Kitamura, Y | 1 |
| Miyoshi, K | 1 |
| Bijlsma, EY | 1 |
| Chan, JS | 1 |
| Olivier, B | 1 |
| Veening, JG | 1 |
| Millan, MJ | 1 |
| Waldinger, MD | 1 |
| Oosting, RS | 1 |
| Shin, E | 2 |
| Lisci, C | 1 |
| Tronci, E | 1 |
| Fidalgo, C | 1 |
| Stancampiano, R | 1 |
| Björklund, A | 2 |
| Carta, M | 3 |
| Azkona, G | 1 |
| Sagarduy, A | 2 |
| Aristieta, A | 1 |
| Vazquez, N | 1 |
| Zubillaga, V | 1 |
| Ruíz-Ortega, JA | 2 |
| Pérez-Navarro, E | 1 |
| Ugedo, L | 2 |
| Sánchez-Pernaute, R | 1 |
| Chee, SS | 1 |
| Menard, JL | 1 |
| Dringenberg, HC | 1 |
| Kolcsar, M | 1 |
| Gáll, Z | 1 |
| Dogaru, MT | 1 |
| Facchin, L | 1 |
| Duboué, ER | 1 |
| Halpern, ME | 1 |
| Llorente, J | 1 |
| Miguelez, C | 1 |
| Morera-Herreras, T | 1 |
| Ohyama, M | 1 |
| Kondo, M | 1 |
| Yamauchi, M | 2 |
| Imanishi, T | 1 |
| Koyama, T | 2 |
| Haleem, DJ | 1 |
| Nawaz, S | 1 |
| Paquette, MA | 1 |
| Foley, K | 1 |
| Brudney, EG | 1 |
| Meshul, CK | 1 |
| Johnson, SW | 1 |
| Berger, SP | 1 |
| Crespi, F | 1 |
| Brunelli, SA | 1 |
| Aviles, JA | 1 |
| Gannon, KS | 1 |
| Branscomb, A | 1 |
| Shacham, S | 1 |
| Grabiec, M | 1 |
| Turlejski, K | 1 |
| Djavadian, R | 1 |
| Bencan, Z | 1 |
| Sledge, D | 1 |
| Shumilov, M | 1 |
| Touitou, E | 1 |
| Inagaki, H | 1 |
| Kiyokawa, Y | 1 |
| Takeuchi, Y | 1 |
| Mori, Y | 1 |
| Kimura, H | 1 |
| Strohl, KP | 1 |
| Magnani, P | 1 |
| Conforti, A | 1 |
| Zanolin, E | 1 |
| Marzotto, M | 1 |
| Bellavite, P | 1 |
| Sato, H | 1 |
| Skelin, I | 1 |
| Diksic, M | 2 |
| Ung, RV | 1 |
| Rouleau, P | 1 |
| Guertin, PA | 1 |
| Olsen, AS | 1 |
| Sozda, CN | 1 |
| Cheng, JP | 1 |
| Hoffman, AN | 1 |
| Kline, AE | 1 |
| Garcia, J | 1 |
| Winkler, C | 1 |
| Nag, N | 1 |
| Tarlac, V | 1 |
| Storey, E | 1 |
| Leong, KC | 1 |
| Goodman, J | 1 |
| Packard, MG | 1 |
| Zheng, Y | 1 |
| Cheung, I | 1 |
| Smith, PF | 1 |
| Eriksen, JL | 1 |
| Gillespie, R | 1 |
| Druse, MJ | 1 |
| Jelen, P | 1 |
| Soltysik, S | 1 |
| Zagrodzka, J | 1 |
| Bell, K | 1 |
| Shokrian, D | 1 |
| Potenzieri, C | 1 |
| Whitaker-Azmitia, PM | 1 |
| Haller, J | 2 |
| Leveleki, C | 2 |
| Baranyi, J | 1 |
| Mikics, E | 2 |
| Bakos, N | 1 |
| Osei-Owusu, P | 1 |
| Scrogin, KE | 1 |
| Mattsson, H | 1 |
| Arani, Z | 1 |
| Astin, M | 1 |
| Bayati, A | 1 |
| Overstreet, DH | 1 |
| Lehmann, A | 1 |
| Lundblad, M | 1 |
| Usiello, A | 1 |
| Håkansson, K | 1 |
| Fisone, G | 1 |
| Cenci, MA | 1 |
| Wisłowska-Stanek, A | 1 |
| Zienowicz, M | 1 |
| Lehner, M | 1 |
| Taracha, E | 1 |
| Bidziński, A | 1 |
| Maciejak, P | 1 |
| Skórzewska, A | 1 |
| Szyndler, J | 1 |
| Płaźnik, A | 1 |
| Papp, M | 1 |
| Litwa, E | 1 |
| Gruca, P | 1 |
| Mocaër, E | 1 |
| Watanabe, A | 1 |
| Hasegawa, S | 1 |
| Nishi, K | 1 |
| Nguyen, KQ | 1 |
| Sziray, N | 1 |
| Levay, G | 1 |
| Barsvári, B | 1 |
| Soproni, K | 1 |
| Furuya, H | 1 |
| Komaki, Y | 1 |
| Okazaki, I | 1 |
| Grundmann, O | 1 |
| Nakajima, J | 1 |
| Seo, S | 1 |
| Butterweck, V | 1 |
| Nishikawa, H | 1 |
| Inoue, T | 1 |
| Masui, T | 1 |
| Izumi, T | 1 |
| O'Mahony, S | 1 |
| Chua, AS | 1 |
| Quigley, EM | 1 |
| Clarke, G | 1 |
| Shanahan, F | 1 |
| Keeling, PW | 1 |
| Dinan, TG | 1 |
| Eison, MS | 1 |
| Suzuki, M | 1 |
| Matsuda, T | 2 |
| Somboonthum, P | 1 |
| Asano, S | 1 |
| Takuma, K | 1 |
| Nogi, H | 1 |
| Baba, A | 2 |
| Klint, T | 1 |
| Andersson, G | 1 |
| Handley, SL | 1 |
| McBlane, JW | 1 |
| Sánchez, C | 1 |
| Abe, M | 2 |
| Tabata, R | 2 |
| Saito, K | 2 |
| Egawa, M | 2 |
| López-Rubalcava, C | 1 |
| Hendrie, CA | 1 |
| Eilam, D | 1 |
| Weiss, SM | 1 |
| Nakai, H | 1 |
| Redrobe, JP | 1 |
| Bourin, M | 1 |
| Hedlund, L | 1 |
| Wahlström, G | 1 |
| Queiroz, CM | 1 |
| Frussa-Filho, R | 1 |
| Reader, TA | 1 |
| Ase, AR | 1 |
| Le Marec, N | 1 |
| Lalonde, R | 1 |
| Kostowski, W | 1 |
| Dyr, W | 1 |
| Krzascik, P | 1 |
| Järbe, T | 1 |
| Archer, T | 1 |
| Naletov, SV | 1 |
| Stoianov, IuB | 1 |
| Kharin, NA | 1 |
| Costello, NL | 1 |
| Carlson, JN | 1 |
| Glick, SD | 1 |
| Tollefson, GD | 1 |
| Kilfoil, T | 1 |
| Michel, A | 1 |
| Montgomery, D | 1 |
| Whiting, RL | 1 |
| File, SE | 1 |
| Gardner, CR | 1 |
| Kennett, GA | 1 |
| Dourish, CT | 1 |
| Curzon, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Perioperative Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery[NCT01505465] | 50 participants (Actual) | Interventional | 2012-02-29 | Completed | |||
| Kynurenine Pathway Metabolites as Novel Translational Biological Markers of Irritable Bowel Syndrome: Relationship to Gastrointestinal Function, Cognition and Co-morbid Depression[NCT01304355] | 85 participants (Anticipated) | Observational | 2011-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Sleep time change from 96 hours before surgery to 72 hours after surgery (NCT01505465)
Timeframe: 96 hours before surgery to 72 hours after surgery
| Intervention | minutes (Mean) |
|---|---|
| Study: Melatonin | 20 |
| Control: Placebo | -55 |
5 reviews available for buspirone and Disease Models, Animal
| Article | Year |
|---|---|
Gene Therapy for Angelman Syndrome: Contemporary Approaches and Future Endeavors.
Topics: Angelman Syndrome; Animals; Anti-Anxiety Agents; Antiparkinson Agents; Buspirone; Diet, Ketogenic; D | 2020 |
Sexual side effects of serotonergic antidepressants: mediated by inhibition of serotonin on central dopamine release?
Topics: Animals; Antidepressive Agents; Aza Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Bupro | 2014 |
[Review of neurobehavioral effects of alcohol-related neurodevelopmental disorder in an animal model].
Topics: Animals; Antioxidants; Buspirone; Disease Models, Animal; Female; Fetal Alcohol Spectrum Disorders; | 2006 |
Serotonin mechanisms in animal models of anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Disease Mo | 1993 |
Anxiety and alcoholism: a serotonin link.
Topics: Alcoholism; Animals; Anxiety Disorders; Brain; Buspirone; Disease Models, Animal; Humans; Personalit | 1991 |
72 other studies available for buspirone and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease.
Topics: Animals; Buspirone; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regula | 2022 |
Buspirone Ameliorates Colon Inflammation in TNBS-Induced Rat Acute Colitis: The Involvement of TLR4/NF-kB Pathway.
Topics: Animals; Anti-Inflammatory Agents; Buspirone; Colitis; Colon; Dexamethasone; Disease Models, Animal; | 2022 |
Serotonergic circuit dysregulation underlying autism-related phenotypes in BTBR mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Buspirone; Disease Models, Animal; Female; Hum | 2023 |
Methodological approach: using a within-subjects design in the marble burying assay.
Topics: Animals; Behavior, Animal; Buspirone; Calcium Carbonate; Disease Models, Animal; Female; Fluoxetine; | 2023 |
Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish.
Topics: Alkaloids; Anabasine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Carbolines | 2021 |
Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs.
Topics: Abdominal Pain; Analgesics; Animals; Buspirone; Cardiovascular System; Disease Models, Animal; Dogs; | 2017 |
The effects of buspirone on occupancy of dopamine receptors and the rat gambling task.
Topics: Animals; Anti-Anxiety Agents; Behavior, Addictive; Buspirone; Cerebellum; Choice Behavior; Corpus St | 2017 |
Embryonic alcohol exposure leading to social avoidance and altered anxiety responses in adult zebrafish.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Buspirone; Disease Mode | 2018 |
Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys.
Topics: Animals; Behavior, Addictive; Benzazepines; Buspirone; Cocaine; Cocaine-Related Disorders; Disease M | 2018 |
Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Buspirone; Disease Models, Animal; D | 2013 |
The anxiolytic buspirone shifts coping strategy in novel environmental context of mice with different anxious phenotype.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; D | 2013 |
Targeting 5-HT(1A) receptors in astrocytes to protect dopaminergic neurons in Parkinsonian models.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Agents; Animals; Astrocytes; Brain; Buspirone; Ce | 2013 |
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
Topics: Amphetamine; Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Benzazepines; Buspirone; Disease | 2014 |
Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in L-DOPA-treated rats.
Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Buspirone; Corpus Striatum; Cyclic AMP Respon | 2014 |
Behavioral anxiolysis without reduction of hippocampal theta frequency after histamine application in the lateral septum of rats.
Topics: Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Disease Models | 2014 |
Dose dependent effects of serotonergic agents on anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Disease Models, Animal; Dose-Res | 2014 |
Disruption of Epithalamic Left-Right Asymmetry Increases Anxiety in Zebrafish.
Topics: Adaptation, Biological; Animals; Animals, Genetically Modified; Anti-Anxiety Agents; Anxiety; Buspir | 2015 |
Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors.
Topics: Action Potentials; Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Buspirone; Desipramine; | 2016 |
Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; Buspir | 2016 |
Inhibition of Reinforcing, Hyperalgesic, and Motor Effects of Morphine by Buspirone in Rats.
Topics: Analgesics; Analysis of Variance; Animals; Buspirone; Conditioning, Operant; Disease Models, Animal; | 2017 |
The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism.
Topics: Animals; Buspirone; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Dyski | 2009 |
Anxiolytics antagonize yohimbine-induced central noradrenergic activity: a concomitant in vivo voltammetry-electrophysiology model of anxiety.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Amygdala; Animals; Anti-Anxiety Agents; Anxiety Dis | 2009 |
PRX-00023, a selective serotonin 1A receptor agonist, reduces ultrasonic vocalizations in infant rats bred for high infantile anxiety.
Topics: Aging; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Anxiety, Separation; Ataxia; Body T | 2009 |
Reduction of the number of new cells reaching olfactory bulbs impairs olfactory perception in the adult opossum.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bromodeoxyuridine; Buspirone; Cell Count; Cues; Dis | 2009 |
Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Chlordiazepoxid | 2009 |
Buspirone transdermal administration for menopausal syndromes, in vitro and in animal model studies.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Buspirone; Disease Models, Animal; Hot Fla | 2010 |
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Mod | 2010 |
Mouse models of apnea: strain differences in apnea expression and its pharmacologic and genetic modification.
Topics: Acetazolamide; Animals; Buspirone; Disease Models, Animal; Humans; Mice; Pulmonary Ventilation; Recu | 2010 |
Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Choice Behavior; Disease Models, Animal; Dose-Resp | 2010 |
Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Buspirone; Depressive Disorder; Disease Models, Animal; Dose-Respon | 2010 |
Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Attention; Buspirone; Disease Models, Animal; Dose-Response R | 2011 |
Functional and physiological effects of treadmill training induced by buspirone, carbidopa, and L-DOPA in clenbuterol-treated paraplegic mice.
Topics: Adipose Tissue; Analysis of Variance; Animals; Biomechanical Phenomena; Body Composition; Body Weigh | 2012 |
Traumatic brain injury-induced cognitive and histological deficits are attenuated by delayed and chronic treatment with the 5-HT1A-receptor agonist buspirone.
Topics: Animals; Brain Injuries; Buspirone; Chronic Disease; Cognition Disorders; Disease Models, Animal; Dr | 2012 |
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
Topics: 5,6-Dihydroxytryptamine; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antiparkinso | 2012 |
Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1.
Topics: Amantadine; Animals; Ataxin-1; Ataxins; Buspirone; Disease Models, Animal; Dopamine Agents; Genotype | 2013 |
Buspirone blocks the enhancing effect of the anxiogenic drug RS 79948-197 on consolidation of habit memory.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Disease Models, Animal; Dose | 2012 |
Performance in anxiety and spatial memory tests following bilateral vestibular loss in the rat and effects of anxiolytic and anxiogenic drugs.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Carbolines; Disease Models, Animal; GABA Antagonis | 2012 |
Effects of ethanol and 5-HT1A agonists on astroglial S100B.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Astrocytes; Buspirone; Cell Differentiation; Cel | 2002 |
22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: behavioral and pharmacological modulation of affective state.
Topics: Animals; Anxiety; Behavior, Animal; Buspirone; Carbolines; Conditioning, Classical; Diagnosis, Diffe | 2003 |
Harm avoidance, anxiety, and response to novelty in the adolescent S-100beta transgenic mouse: role of serotonin and relevance to Down syndrome.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Buspirone; Disease Models, Animal; Dose-Resp | 2003 |
Stress, social avoidance and anxiolytics: a potential model of stress-induced anxiety.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Chlordiazepoxide; Disease Models, Animal; Electric Stimulat | 2003 |
Buspirone raises blood pressure through activation of sympathetic nervous system and by direct activation of alpha1-adrenergic receptors after severe hemorrhage.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Buspirone; Disease Models, Animal; | 2004 |
Altered neuroendocrine response and gastric dysmotility in the Flinders Sensitive Line rat.
Topics: Animals; Buspirone; Corticosterone; Disease Models, Animal; Dyspepsia; Gastrointestinal Motility; Ma | 2005 |
Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
Topics: Adenosine A2 Receptor Agonists; Adrenergic Agents; Amantadine; Animals; Antiparkinson Agents; Basal | 2005 |
Buspirone attenuates conditioned fear-induced c-Fos expression in the rat hippocampus.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Avoidance Learning; Buspirone; Conditioning, Psycho | 2005 |
Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety.
Topics: Acetamides; Animals; Anti-Anxiety Agents; Arousal; Brain; Buspirone; Chronotherapy; Conditioning, Cl | 2006 |
Chronic buspirone treatment normalizes regional serotonin synthesis in the olfactory bulbectomized rat brain: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Buspirone; Carbon Radioisotopes; Denervation; Depressive Disorder; | 2006 |
Pharmacological evaluation of the stress-induced social avoidance model of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Chlordiazepoxide; Diazepam; Disea | 2006 |
Anti-anxiety effects of Apocynum venetum L. in the elevated plus maze test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Apocynum; Behavior, Animal; Buspirone; Diazepam; Disease Mode | 2007 |
Effects of cytochrome P450 (CYP) 3A4 inhibitors on the anxiolytic action of tandospirone in rat contextual conditioned fear.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; | 2007 |
Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model.
Topics: Adolescent; Adult; Animals; Animals, Newborn; Buspirone; Disease Models, Animal; Female; Humans; Irr | 2008 |
Use of animal models: toward anxioselective drugs.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Benzodiazepines; Buspirone; Confl | 1984 |
Effects of serotonin1A agonists on anoxia-induced impairment of protein synthesis in rat brain slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Ischemia; Buspirone; Carbon Isotopes; | 1995 |
Ultrasound vocalization is not related to corticosterone response in isolated rat pups.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Anxiety; Buspirone; Corticosteron | 1994 |
Serotonergic mechanisms involved in the exploratory behaviour of mice in a fully automated two-compartment black and white text box.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; A | 1995 |
Novel benzodioxan derivative, 5-[3-[((2S)-1,4-benzodioxan-2-ylmethyl) amino]propoxy]-1,3-benzodioxole HCl (MKC-242), with anxiolytic-like and antidepressant-like effects in animal models.
Topics: Animals; Buspirone; Dioxanes; Dioxoles; Disease Models, Animal; Dose-Response Relationship, Drug; Dr | 1996 |
Pre- or postsynaptic activity of 5-HT1A compounds in mice depends on the anxiety paradigm.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Buspirone; Disease Model | 1996 |
Effects of diazepam and buspirone on the behaviour of wild voles (Microtus socialis) in two models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Arvicolinae; Behavior, Animal; Buspirone; Diazepam; Disease M | 1997 |
Effect of 5-[3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy]-1,3-benzodioxole HCl (MKC-242), a novel 5-HT1A-receptor agonist, on aggressive behavior and marble burying behavior in mice.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Diazepam; Dioxanes; Dioxoles; Disease | 1998 |
Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Buspirone; Citalopram; Depression; Disease Models, Animal; Dose-Resp | 1998 |
Acute and long term effects of buspirone treatments on voluntary ethanol intake in a rat model of alcoholism.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Buspirone; Disease Models, Animal; Dose-Res | 1999 |
Effects of buspirone on an animal model of tardive dyskinesia.
Topics: Adrenergic Uptake Inhibitors; Animals; Buspirone; Disease Models, Animal; Dopamine; Dyskinesia, Drug | 1999 |
Differential effects of L-trytophan and buspirone on biogenic amine contents and metabolism in Lurcher mice cerebellum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Buspirone; Cerebellar Ataxia; Cerebellum; | 2000 |
5-Hydroxytryptamine1A receptor agonists in animal models of depression and anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Buspirone; Chromans; Depression; Disease M | 1992 |
[The antiemetic activity of buspirone].
Topics: Animals; Antiemetics; Apomorphine; Buspirone; Cisplatin; Columbidae; Disease Models, Animal; Drug Ev | 1992 |
Acute administration of diazepam and buspirone in rats trained on conflict schedules having different degrees of predictability.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Conditioning, Psychological; Conflict, Psychologic | 1991 |
Effects of anxiolytic and anxiogenic drugs on exploratory activity in a simple model of anxiety in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Chlordiazepoxide; Disease Models, Animal; Explorat | 1989 |
Models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Disease Models, Animal; Humans; Neuropsy | 1985 |
Recent developments in 5HT-related pharmacology of animal models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Disease Models, Animal; Piperidines; Pyrimidines; | 1986 |
Antidepressant-like action of 5-HT1A agonists and conventional antidepressants in an animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodi | 1987 |