Page last updated: 2024-10-24

buspirone and Colicky Pain

buspirone has been researched along with Colicky Pain in 6 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Research Excerpts

ExcerptRelevanceReference
"Buspirone effectively improves pain and associated psychological symptoms including depressive symptoms, anxiety, somatization, and sleep disturbances in childhood FAP but has no superiority over placebo."9.34Comparison of the Efficacy of Buspirone and Placebo in Childhood Functional Abdominal Pain: A Randomized Clinical Trial. ( Badihian, N; Badihian, S; Saneian, H; Shahsanai, A; Yaghini, O, 2020)
" In this study performed on male Wistar rats, we used microelectrode recording of the caudal ventrolateral medulla (CVLM) neuron responses to colorectal distension (CRD) and electromyography recording of CRD-evoked visceromotor reactions (VMRs) to evaluate post-colitis changes in the effects of 5-HT1A agonist buspirone on supraspinal visceral nociceptive transmission."8.31Opposing effects of 5-HT1A receptor agonist buspirone on supraspinal abdominal pain transmission in normal and visceral hypersensitive rats. ( Busygina, II; Lyubashina, OA; Sivachenko, IB; Sushkevich, BM, 2023)
"Using animal model of abdominal pain (urethane-anaesthetized rats), based on the noxious colorectal distension (CRD) as pain stimulus we studied effects of buspirone (1."7.88The central effects of buspirone on abdominal pain in rats. ( Lyubashina, OA; Panteleev, SS; Sivachenko, IB, 2018)
"Buspirone was eventually introduced."5.62Buspirone in the management of refractory irritable bowel syndrome: A case report. ( Al-Baz, N; Alabdulla, M; Haddad, PM; Karim, MA; Reagu, SM, 2021)
"Buspirone effectively improves pain and associated psychological symptoms including depressive symptoms, anxiety, somatization, and sleep disturbances in childhood FAP but has no superiority over placebo."5.34Comparison of the Efficacy of Buspirone and Placebo in Childhood Functional Abdominal Pain: A Randomized Clinical Trial. ( Badihian, N; Badihian, S; Saneian, H; Shahsanai, A; Yaghini, O, 2020)
" In this study performed on male Wistar rats, we used microelectrode recording of the caudal ventrolateral medulla (CVLM) neuron responses to colorectal distension (CRD) and electromyography recording of CRD-evoked visceromotor reactions (VMRs) to evaluate post-colitis changes in the effects of 5-HT1A agonist buspirone on supraspinal visceral nociceptive transmission."4.31Opposing effects of 5-HT1A receptor agonist buspirone on supraspinal abdominal pain transmission in normal and visceral hypersensitive rats. ( Busygina, II; Lyubashina, OA; Sivachenko, IB; Sushkevich, BM, 2023)
"Using animal model of abdominal pain (urethane-anaesthetized rats), based on the noxious colorectal distension (CRD) as pain stimulus we studied effects of buspirone (1."3.88The central effects of buspirone on abdominal pain in rats. ( Lyubashina, OA; Panteleev, SS; Sivachenko, IB, 2018)
"Buspirone was eventually introduced."1.62Buspirone in the management of refractory irritable bowel syndrome: A case report. ( Al-Baz, N; Alabdulla, M; Haddad, PM; Karim, MA; Reagu, SM, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Karim, MA1
Al-Baz, N1
Haddad, PM1
Reagu, SM1
Alabdulla, M1
Lyubashina, OA4
Sivachenko, IB3
Sushkevich, BM1
Busygina, II2
Badihian, N1
Yaghini, O1
Badihian, S1
Shahsanai, A1
Saneian, H1
Panteleev, SS3
Nozdrachev, AD1

Trials

1 trial available for buspirone and Colicky Pain

ArticleYear
Comparison of the Efficacy of Buspirone and Placebo in Childhood Functional Abdominal Pain: A Randomized Clinical Trial.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:5

    Topics: Abdominal Pain; Adolescent; Anxiety; Buspirone; Child; Depression; Female; Humans; Male; Pain Measur

2020

Other Studies

5 other studies available for buspirone and Colicky Pain

ArticleYear
Buspirone in the management of refractory irritable bowel syndrome: A case report.
    Medicine, 2021, Dec-23, Volume: 100, Issue:51

    Topics: Abdominal Pain; Adult; Buspirone; Humans; Irritable Bowel Syndrome; Male; Quality of Life; Serotonin

2021
Opposing effects of 5-HT1A receptor agonist buspirone on supraspinal abdominal pain transmission in normal and visceral hypersensitive rats.
    Journal of neuroscience research, 2023, Volume: 101, Issue:10

    Topics: Abdominal Pain; Animals; Buspirone; Colitis; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A;

2023
The Buspirone-dependent Abdominal Pain Transmission Within the Nucleus Tractus Solitarius in the Rat.
    Neuroscience, 2021, 01-01, Volume: 452

    Topics: Abdominal Pain; Animals; Buspirone; Humans; Neurons; Rats; Solitary Nucleus; Synaptic Transmission

2021
Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs.
    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2017, Volume: 473, Issue:1

    Topics: Abdominal Pain; Analgesics; Animals; Buspirone; Cardiovascular System; Disease Models, Animal; Dogs;

2017
The central effects of buspirone on abdominal pain in rats.
    Neurogastroenterology and motility, 2018, Volume: 30, Issue:11

    Topics: Abdominal Pain; Animals; Buspirone; Medulla Oblongata; Neurons; Rats; Rats, Wistar; Serotonin Recept

2018