Page last updated: 2024-10-24

buspirone and Bipolar Disorder

buspirone has been researched along with Bipolar Disorder in 14 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"The severity of ataxia varies according to the extent of the lesion."5.31Ataxia from lithium toxicity successfully treated with high-dose buspirone: a single-case experimental design. ( Megna, J; O'dell, M, 2001)
"Buspirone therapy was initiated at 15 mg/day with individual dose titration to a maximum of 90 mg/day and resulted in marked improvement in both depressive and anxiety symptoms."2.67Clinical effects of the 5-HT1A partial agonists in depression: a composite analysis of buspirone in the treatment of depression. ( Alms, DR; Andary, JJ; Fabre, LF; Feighner, J; Gammans, RE; Messina, ME; Rickels, K; Robinson, DS; Shrotriya, RC, 1990)
"The severity of ataxia varies according to the extent of the lesion."1.31Ataxia from lithium toxicity successfully treated with high-dose buspirone: a single-case experimental design. ( Megna, J; O'dell, M, 2001)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's7 (50.00)18.2507
2000's5 (35.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nierenberg, AA1
Preskorn, SH1
Yatham, LN1
Nath, J1
Sagar, R1
Megna, J1
O'dell, M1
Spinella, M1
Eaton, LA1
Iruela, LM1
IbaƱez-Rojo, V1
Caballero, L1
Baca, E1
McIvor, R1
Sinanan, K1
Robinson, DS1
Rickels, K1
Feighner, J1
Fabre, LF1
Gammans, RE1
Shrotriya, RC1
Alms, DR1
Andary, JJ1
Messina, ME1
Rock, NL1
McDaniel, JS1
Ninan, PT1
Magnuson, JV1
Price, WA1
Bielefeld, M1
Liegghio, NE1
Yeragani, VK1

Trials

1 trial available for buspirone and Bipolar Disorder

ArticleYear
Clinical effects of the 5-HT1A partial agonists in depression: a composite analysis of buspirone in the treatment of depression.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Buspirone; Depressive Disorder; Double-Blind Method; Fema

1990

Other Studies

13 other studies available for buspirone and Bipolar Disorder

ArticleYear
Low-dose buspirone, melatonin and low-dose bupropion added to mood stabilizers for severe treatment-resistant bipolar depression.
    Psychotherapy and psychosomatics, 2009, Volume: 78, Issue:6

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Bupropion; Buspirone; Drug Therapy, Combination; Fem

2009
Mania in a case of polypsychopharmacology: pharmacodynamic and pharmacokinetic considerations. Do you believe in magic?
    Journal of psychiatric practice, 2007, Volume: 13, Issue:3

    Topics: Adjustment Disorders; Adolescent; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Buspirone

2007
Buspirone induced prolactin release in mania.
    Biological psychiatry, 1994, Apr-15, Volume: 35, Issue:8

    Topics: Adult; Bipolar Disorder; Buspirone; Female; Humans; Male; Middle Aged; Prolactin; Reference Values;

1994
Drugs for psychiatric disorders.
    The Medical letter on drugs and therapeutics, 1997, Apr-11, Volume: 39, Issue:998

    Topics: Aged; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Benzodi

1997
Late-onset bipolar disorder due to hyperthyroidism.
    Acta psychiatrica Scandinavica, 2001, Volume: 104, Issue:1

    Topics: Adult; Aged; Anti-Anxiety Agents; Bipolar Disorder; Buspirone; Humans; Hyperthyroidism; Male; Middle

2001
Ataxia from lithium toxicity successfully treated with high-dose buspirone: a single-case experimental design.
    Archives of physical medicine and rehabilitation, 2001, Volume: 82, Issue:8

    Topics: Activities of Daily Living; Ataxia; Bipolar Disorder; Buspirone; Drug Overdose; Female; Humans; Lith

2001
Hypomania induced by herbal and pharmaceutical psychotropic medicines following mild traumatic brain injury.
    Brain injury, 2002, Volume: 16, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Bipolar Disorder; Brain Injuries; Buspirone; Depression; Drug Interactio

2002
Buspirone-induced mania: possible interaction with disulfiram.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Alcoholism; Bipolar Disorder; Buspirone; Disulfiram; Drug Therapy, Combination; Humans

1991
Buspirone-induced mania.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 158

    Topics: Adult; Alcoholism; Anxiety Disorders; Bipolar Disorder; Buspirone; Ethanol; Humans; Male

1991
Possible adverse effects of buspirone when used with other psychotropic drugs.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Adult; Akathisia, Drug-Induced; Bipolar Disorder; Buspirone; Dose-Response Relationship, Drug; Drug

1990
Possible induction of mania by buspirone.
    The American journal of psychiatry, 1990, Volume: 147, Issue:1

    Topics: Adult; Bipolar Disorder; Buspirone; Female; Humans; Psychoses, Substance-Induced

1990
Buspirone-induced mania.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:2

    Topics: Adult; Bipolar Disorder; Buspirone; Humans; Male

1989
Buspirone-induced hypomania: a case report.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:3

    Topics: Adult; Bipolar Disorder; Buspirone; Female; Humans

1988