buspirone has been researched along with Autosomal Dominant Cerebellar Ataxia, Type II in 4 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Buspirone was not shown to be superior to placebo in the treatment of patients with SCA." | 2.73 | Treatment of spinocerebellar ataxia with buspirone. ( Assadi, M; Campellone, JV; Janson, CG; Leone, P; Schwartzman, RJ; Veloski, JJ, 2007) |
| "Spinocerebellar ataxias are autosomal dominant diseases, associated in some types with a CAG repeat expansion, and characterised by a progressive loss of motor function." | 1.39 | Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1. ( Nag, N; Storey, E; Tarlac, V, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nag, N | 1 |
| Tarlac, V | 1 |
| Storey, E | 1 |
| Assadi, M | 2 |
| Campellone, JV | 2 |
| Janson, CG | 2 |
| Veloski, JJ | 2 |
| Schwartzman, RJ | 2 |
| Leone, P | 2 |
| Gazulla, J | 1 |
| Modrego, P | 1 |
2 trials available for buspirone and Autosomal Dominant Cerebellar Ataxia, Type II
| Article | Year |
|---|---|
Treatment of spinocerebellar ataxia with buspirone.
Topics: Adolescent; Adult; Aged; Brain; Buspirone; Cross-Over Studies; Dizziness; DNA Mutational Analysis; D | 2007 |
Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia.
Topics: Adult; Buspirone; Cross-Over Studies; Disability Evaluation; Double-Blind Method; Female; Humans; Ma | 2008 |
2 other studies available for buspirone and Autosomal Dominant Cerebellar Ataxia, Type II
| Article | Year |
|---|---|
Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1.
Topics: Amantadine; Animals; Ataxin-1; Ataxins; Buspirone; Disease Models, Animal; Dopamine Agents; Genotype | 2013 |
Buspirone and serotonin in spinocerebellar ataxia.
Topics: Buspirone; Humans; Serotonin; Serotonin Receptor Agonists; Spinocerebellar Ataxias | 2008 |