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buspirone and Agoraphobia

buspirone has been researched along with Agoraphobia in 11 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Agoraphobia: Obsessive, persistent, intense fear of open places.

Research Excerpts

ExcerptRelevanceReference
"This multicentre study compared a 16-week buspirone treatment with placebo in patients presenting with panic disorder with agoraphobia and also receiving cognitive behaviour therapy (CBT)."9.08A controlled study of cognitive behaviour therapy with buspirone or placebo in panic disorder with agoraphobia. ( Bernard, G; Bouvard, M; Chneiweiss, L; Cottraux, J; Cungi, C; Heim, F; Légeron, P; Note, ID, 1995)
"This multicentre study compared a 16-week buspirone treatment with placebo in patients presenting with panic disorder with agoraphobia and also receiving cognitive behaviour therapy (CBT)."5.08A controlled study of cognitive behaviour therapy with buspirone or placebo in panic disorder with agoraphobia. ( Bernard, G; Bouvard, M; Chneiweiss, L; Cottraux, J; Cungi, C; Heim, F; Légeron, P; Note, ID, 1995)
"Thirty-six patients with generalised anxiety disorder, panic disorder or agoraphobia with panic attacks, diagnosed by DSM-III criteria, were treated with a new non-benzodiazepine anti-anxiety drug, buspirone, and with diazepam and placebo, in a cross-over design."5.05Anxiety in primary care: is short-term drug treatment appropriate? ( Owen, R; Tyrer, P, 1984)
"Buspirone was compared with imipramine and placebo in the treatment of panic disorder in an 8-week, double-blind controlled study of 52 randomly assigned patients."2.67Is buspirone effective for panic disorder? ( Raj, AB; Sheehan, DV; Sheehan, KH; Soto, S, 1990)
"Panic disorder is characterised by recurrent unexpected panic attacks consisting of a wave of intense fear that reaches a peak within a few minutes."2.61Benzodiazepines versus placebo for panic disorder in adults. ( Barbui, C; Bighelli, I; Breilmann, J; Castellazzi, M; Cipriani, A; Davies, SJ; Furukawa, TA; Girlanda, F; Guaiana, G; Koesters, M, 2019)
"Panic disorder is common in the general population."2.50Azapirones versus placebo for panic disorder in adults. ( Barbui, C; Bighelli, I; Castellazzi, M; Chen, P; Cipriani, A; Furukawa, TA; Girlanda, F; Guaiana, G; Imai, H; Koesters, M; Pompoli, A; Tajika, A, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breilmann, J1
Girlanda, F2
Guaiana, G2
Barbui, C2
Cipriani, A2
Castellazzi, M2
Bighelli, I2
Davies, SJ1
Furukawa, TA2
Koesters, M2
Imai, H1
Tajika, A1
Chen, P1
Pompoli, A1
Dannawi, M1
Dinan, T1
Tyrer, P1
Owen, R1
Cottraux, J2
Note, ID1
Cungi, C1
Légeron, P1
Heim, F1
Chneiweiss, L1
Bernard, G1
Bouvard, M2
Mollard, E1
Guerin, J1
Sheehan, DV1
Raj, AB1
Sheehan, KH1
Soto, S1
Pohl, R1
Balon, R1
Yeragani, VK1
Gershon, S1
Teicher, MH1
Rickels, K1

Reviews

4 reviews available for buspirone and Agoraphobia

ArticleYear
Benzodiazepines versus placebo for panic disorder in adults.
    The Cochrane database of systematic reviews, 2019, Mar-28, Volume: 3

    Topics: Adult; Aged; Agoraphobia; Benzodiazepines; Buspirone; Humans; Imipramine; Middle Aged; Numbers Neede

2019
Azapirones versus placebo for panic disorder in adults.
    The Cochrane database of systematic reviews, 2014, Sep-30, Issue:9

    Topics: Adult; Agoraphobia; Anti-Anxiety Agents; Buspirone; Humans; Panic Disorder; Randomized Controlled Tr

2014
Therapeutic options: Addressing the current dilemma.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16 Suppl 2

    Topics: Adrenergic Uptake Inhibitors; Agoraphobia; Algorithms; Anti-Anxiety Agents; Antidepressive Agents; A

2006
Biology of anxiety.
    The Medical clinics of North America, 1988, Volume: 72, Issue:4

    Topics: Agoraphobia; Anxiety Disorders; Buspirone; Fear; Humans; Panic; Phobic Disorders; Receptors, GABA-A

1988

Trials

5 trials available for buspirone and Agoraphobia

ArticleYear
Anxiety in primary care: is short-term drug treatment appropriate?
    Journal of psychiatric research, 1984, Volume: 18, Issue:1

    Topics: Adult; Agoraphobia; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Female; Humans

1984
A controlled study of cognitive behaviour therapy with buspirone or placebo in panic disorder with agoraphobia.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 167, Issue:5

    Topics: Adolescent; Adult; Agoraphobia; Anti-Anxiety Agents; Buspirone; Cognitive Behavioral Therapy; Depres

1995
Study and course of the psychological profile in 77 patients expressing panic disorder with agoraphobia after cognitive behaviour therapy with or without buspirone.
    Psychotherapy and psychosomatics, 1997, Volume: 66, Issue:1

    Topics: Adult; Agoraphobia; Anti-Anxiety Agents; Buspirone; Cognitive Behavioral Therapy; Combined Modality

1997
Is buspirone effective for panic disorder?
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:1

    Topics: Adult; Agoraphobia; Anxiety Disorders; Arousal; Buspirone; Double-Blind Method; Fear; Female; Follow

1990
Serotonergic anxiolytics in the treatment of panic disorder: a controlled study with buspirone.
    Psychopathology, 1989, Volume: 22 Suppl 1

    Topics: Adult; Agoraphobia; Brain; Buspirone; Clinical Trials as Topic; Double-Blind Method; Fear; Female; H

1989

Other Studies

2 other studies available for buspirone and Agoraphobia

ArticleYear
Possible serotonin syndrome after combination of buspirone and St John's Wort.
    Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:4

    Topics: Adult; Agoraphobia; Buspirone; Drug Interactions; Female; Humans; Hypericum; Psychiatric Status Rati

2002
Clinical studies of "specific" anxiolytics as therapeutic agents.
    Psychopharmacology series, 1987, Volume: 3

    Topics: Agoraphobia; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Humans; Mental Diso

1987