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buspirone and Aging

buspirone has been researched along with Aging in 6 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Buspirone was not removed by hemodialysis."2.37Metabolism and disposition of buspirone. ( Gammans, RE; LaBudde, JA; Mayol, RF, 1986)
" We recently showed that maternal buspirone, a 5-HT1A receptor agonist, protects against the adverse effects of in utero stress on depression and pain in adult rat offspring."1.37Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences. ( Aloisi, AM; Butkevich, IP; Mikhailenko, VA; Otellin, VA; Vershinina, EA, 2011)
"Buspirone treatment was well-tolerated by all subjects even though the 45 mg/day dose was 3 times the recommended starting dose in clinical practice."1.28Pharmacokinetics of buspirone in elderly subjects. ( Gammans, RE; LaBudde, JA; Mayol, RF; Shea, JP; Westrick, ML, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wills, TA1
Knapp, DJ1
Overstreet, DH1
Breese, GR1
Brunelli, SA1
Aviles, JA1
Gannon, KS1
Branscomb, A1
Shacham, S1
Butkevich, IP1
Mikhailenko, VA1
Vershinina, EA1
Otellin, VA1
Aloisi, AM1
Rhoads, DE1
Grimes, N1
Kaushal, S1
Mallari, J1
Orlando, K1
Gammans, RE2
Westrick, ML1
Shea, JP1
Mayol, RF2
LaBudde, JA2

Reviews

1 review available for buspirone and Aging

ArticleYear
Metabolism and disposition of buspirone.
    The American journal of medicine, 1986, Mar-31, Volume: 80, Issue:3B

    Topics: Absorption; Administration, Oral; Adolescent; Adult; Aged; Aging; Amitriptyline; Animals; Anxiety Di

1986

Other Studies

5 other studies available for buspirone and Aging

ArticleYear
Sensitization, duration, and pharmacological blockade of anxiety-like behavior following repeated ethanol withdrawal in adolescent and adult rats.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:3

    Topics: Aging; Alcohol Drinking; Animals; Anxiety; Buspirone; Central Nervous System Depressants; Ethanol; F

2009
PRX-00023, a selective serotonin 1A receptor agonist, reduces ultrasonic vocalizations in infant rats bred for high infantile anxiety.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 94, Issue:1

    Topics: Aging; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Anxiety, Separation; Ataxia; Body T

2009
Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences.
    Brain research, 2011, Oct-24, Volume: 1419

    Topics: Aging; Animals; Animals, Newborn; Buspirone; Chronic Pain; Depressive Disorder; Female; Inflammation

2011
Decision time and perseveration of adolescent rats in the T-maze are affected differentially by buspirone and independent of 5-HT-1A expression.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 102, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Buspirone; Decision Making; Gene Expression

2012
Pharmacokinetics of buspirone in elderly subjects.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:1

    Topics: Adult; Aged; Aging; Buspirone; Female; Half-Life; Humans; Male; Racial Groups

1989