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buspirone and Adiadochokinesis

buspirone has been researched along with Adiadochokinesis in 9 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Research Excerpts

ExcerptRelevanceReference
"Buspirone, a 5HT-agonist and D2-dopamine antagonist/agonist, has modest beneficial effects in younger individuals with cerebellar ataxia."9.11The role of buspirone for the treatment of cerebellar ataxia in an older individual. ( Black, SE; Herrmann, N; Holroyd-Leduc, JM; Liu, BA; Maki, BE; Zecevic, A, 2005)
"To evaluate the efficacy of buspirone hydrochloride, a serotonin (5-hydroxytryptamine1A) agonist, in treating patients with cerebellar ataxia."9.08Use of buspirone for treatment of cerebellar ataxia. An open-label study. ( Gatev, P; Goldfarb, L; Hallett, M; Lou, JS; McShane, L, 1995)
"To establish the antiataxic effect of buspirone hydrochloride, a serotonergic 5-hydroxytryptamine1A (5-HT1A) agonist, in a homogenous group of patients characterized by the same well-defined single condition, cerebellar cortical atrophy."9.08Buspirone, a 5-hydroxytryptamine1A agonist, is active in cerebellar ataxia. Results of a double-blind drug placebo study in patients with cerebellar cortical atrophy. ( Adeleine, P; Dumas, R; Honnorat, J; Laurent, B; Michel, D; Nighoghossian, N; Trouillas, P; Vighetto, A; Xie, J, 1997)
"We propose a serotonergic hypothesis for cerebellar ataxia."5.29[Effect of buspirone, a serotonergic 5-HT-1A agonist in cerebellar ataxia: a pilot study. Preliminary communication]. ( Adeleine, P; Derex, L; Getenet, JC; Honnorat, J; Nighoghossian, N; Riche, G; Trouillas, P; Xie, J, 1995)
"Buspirone, a 5HT-agonist and D2-dopamine antagonist/agonist, has modest beneficial effects in younger individuals with cerebellar ataxia."5.11The role of buspirone for the treatment of cerebellar ataxia in an older individual. ( Black, SE; Herrmann, N; Holroyd-Leduc, JM; Liu, BA; Maki, BE; Zecevic, A, 2005)
"To evaluate the efficacy of buspirone hydrochloride, a serotonin (5-hydroxytryptamine1A) agonist, in treating patients with cerebellar ataxia."5.08Use of buspirone for treatment of cerebellar ataxia. An open-label study. ( Gatev, P; Goldfarb, L; Hallett, M; Lou, JS; McShane, L, 1995)
"To establish the antiataxic effect of buspirone hydrochloride, a serotonergic 5-hydroxytryptamine1A (5-HT1A) agonist, in a homogenous group of patients characterized by the same well-defined single condition, cerebellar cortical atrophy."5.08Buspirone, a 5-hydroxytryptamine1A agonist, is active in cerebellar ataxia. Results of a double-blind drug placebo study in patients with cerebellar cortical atrophy. ( Adeleine, P; Dumas, R; Honnorat, J; Laurent, B; Michel, D; Nighoghossian, N; Trouillas, P; Vighetto, A; Xie, J, 1997)
"We propose a serotonergic hypothesis for cerebellar ataxia."1.29[Effect of buspirone, a serotonergic 5-HT-1A agonist in cerebellar ataxia: a pilot study. Preliminary communication]. ( Adeleine, P; Derex, L; Getenet, JC; Honnorat, J; Nighoghossian, N; Riche, G; Trouillas, P; Xie, J, 1995)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takei, A1
Hamada, T1
Yabe, I1
Sasaki, H1
Holroyd-Leduc, JM1
Liu, BA1
Maki, BE1
Zecevic, A1
Herrmann, N1
Black, SE1
Lou, JS1
Goldfarb, L1
McShane, L1
Gatev, P1
Hallett, M1
Trouillas, P4
Xie, J4
Getenet, JC1
Adeleine, P4
Nighoghossian, N2
Honnorat, J2
Riche, G1
Derex, L1
Michel, D1
Vighetto, A1
Dumas, R1
Laurent, B1
Reader, TA1
Ase, AR1
Le Marec, N1
Lalonde, R1
Hassin-Baer, S1
Korczyn, AD1
Giladi, N1

Reviews

1 review available for buspirone and Adiadochokinesis

ArticleYear
Treatment of cerebellar ataxia with 5-HT1A agonist.
    Cerebellum (London, England), 2005, Volume: 4, Issue:3

    Topics: Buspirone; Cerebellar Ataxia; Clinical Trials as Topic; Humans; Serotonin 5-HT1 Receptor Agonists; S

2005

Trials

5 trials available for buspirone and Adiadochokinesis

ArticleYear
The role of buspirone for the treatment of cerebellar ataxia in an older individual.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2005,Fall, Volume: 12, Issue:3

    Topics: Aged, 80 and over; Buspirone; Cerebellar Ataxia; Double-Blind Method; Gait; Humans; Male; Postural B

2005
Use of buspirone for treatment of cerebellar ataxia. An open-label study.
    Archives of neurology, 1995, Volume: 52, Issue:10

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Buspirone; Cerebellar Ataxia; Depression; Female; Humans;

1995
Treatment of cerebellar ataxia with buspirone: a double-blind study.
    Lancet (London, England), 1996, Sep-14, Volume: 348, Issue:9029

    Topics: Adult; Buspirone; Cerebellar Ataxia; Double-Blind Method; Humans; Middle Aged; Placebos; Serotonin R

1996
Buspirone, a serotonergic 5-HT1A agonist, is active in cerebellar ataxia. A new fact in favor of the serotonergic theory of ataxia.
    Progress in brain research, 1997, Volume: 114

    Topics: Anxiety; Atrophy; Buspirone; Cerebellar Ataxia; Cerebellar Cortex; Cerebellum; Humans; Middle Aged;

1997
Buspirone, a 5-hydroxytryptamine1A agonist, is active in cerebellar ataxia. Results of a double-blind drug placebo study in patients with cerebellar cortical atrophy.
    Archives of neurology, 1997, Volume: 54, Issue:6

    Topics: Adult; Atrophy; Buspirone; Cerebellar Ataxia; Cerebellum; Double-Blind Method; Humans; Middle Aged;

1997

Other Studies

3 other studies available for buspirone and Adiadochokinesis

ArticleYear
[Effect of buspirone, a serotonergic 5-HT-1A agonist in cerebellar ataxia: a pilot study. Preliminary communication].
    Revue neurologique, 1995, Volume: 151, Issue:12

    Topics: Adult; Buspirone; Cerebellar Ataxia; Drug Evaluation; Humans; Serotonin Receptor Agonists; Time Fact

1995
Differential effects of L-trytophan and buspirone on biogenic amine contents and metabolism in Lurcher mice cerebellum.
    Neuroscience letters, 2000, Feb-25, Volume: 280, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Buspirone; Cerebellar Ataxia; Cerebellum;

2000
An open trial of amantadine and buspirone for cerebellar ataxia: a disappointment.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:10

    Topics: Adult; Aged; Amantadine; Buspirone; Cerebellar Ataxia; Clinical Trials as Topic; Disease Progression

2000