buspirone and ADDH
buspirone has been researched along with ADDH in 12 studies
Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Buspirone has a favorable side-effects profile." | 2.75 | Buspirone versus methylphenidate in the treatment of attention deficit hyperactivity disorder: a double-blind and randomized trial. ( Amini, H; Davari-Ashtiani, R; Mazhabdar, H; Razjouyan, K; Shahrbabaki, ME, 2010) |
| "Methylphenidate as a psycho stimulant drug has been prescribed in neuropsychiatric disorders to increase cognition and attention therefore is a medication of choice for attention-deficit/hyperactivity disorder however long-term administration of central nervous system stimulant produces tolerance on cognitive behavior." | 1.42 | Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration. ( Alam, N; Khan, SS; Najam, R, 2015) |
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Haleem, DJ | 1 |
| Salman, T | 1 |
| Nawaz, S | 1 |
| Ikram, H | 1 |
| Yüce, M | 1 |
| Karabekiroğlu, K | 1 |
| Say, GN | 1 |
| Müjdeci, M | 1 |
| Oran, M | 1 |
| Alam, N | 1 |
| Najam, R | 1 |
| Khan, SS | 1 |
| Matsui, Y | 1 |
| Matsunaga, S | 1 |
| Matsuda, Y | 1 |
| Kishi, T | 1 |
| Iwata, N | 1 |
| Davari-Ashtiani, R | 1 |
| Shahrbabaki, ME | 1 |
| Razjouyan, K | 1 |
| Amini, H | 1 |
| Mazhabdar, H | 1 |
| Sutherland, SM | 1 |
| Adler, LA | 1 |
| Chen, C | 1 |
| Smith, MD | 1 |
| Feltner, DE | 1 |
| Mohammadi, MR | 1 |
| Hafezi, P | 1 |
| Galeiha, A | 1 |
| Hajiaghaee, R | 1 |
| Akhondzadeh, S | 1 |
| Niederhofer, H | 1 |
| Gross, MD | 1 |
| Malhotra, S | 1 |
| Santosh, PJ | 1 |
| Quiason, N | 1 |
| Ward, D | 1 |
| Kitchen, T | 1 |
| Balon, R | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Eight-Week, Double-Blind, 3-Arm Parallel, Placebo-Controlled, Randomized Efficacy And Safety Trial Of Atomoxetine, Atomoxetine Plus Buspirone, And Placebo In Adults With Attention Deficit Hyperactivity Disorder[NCT00174226] | Phase 2 | 241 participants (Actual) | Interventional | 2004-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for buspirone and ADDH
| Article | Year |
|---|---|
Azapirones for Attention Deficit Hyperactivity Disorder: A Systematic Review.
Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Humans; Randomized Controlled Trials as To | 2016 |
Trials
5 trials available for buspirone and ADDH
| Article | Year |
|---|---|
Buspirone versus methylphenidate in the treatment of attention deficit hyperactivity disorder: a double-blind and randomized trial.
Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous System Stimulants; Child; | 2010 |
An 8-week, randomized controlled trial of atomoxetine, atomoxetine plus buspirone, or placebo in adults with ADHD.
Topics: Adult; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Buspirone; Double-B | 2012 |
Buspirone versus methylphenidate in the treatment of children with attention- deficit/ hyperactivity disorder: randomized double-blind study.
Topics: Adolescent; Algorithms; Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous Sy | 2012 |
An open trial of buspirone in the treatment of attention-deficit disorder.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Attention Deficit Disorder with Hyperactivity; Buspirone; Do | 2003 |
An open clinical trial of buspirone in children with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Female; Humans; India; Male; Matche | 1998 |
Other Studies
6 other studies available for buspirone and ADDH
| Article | Year |
|---|---|
Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous System Stimulants | 2022 |
Buspirone use in the treatment of atomoxetine-induced bruxism.
Topics: Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivi | 2013 |
Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Avoidance Learning; Buspirone; Central Nervo | 2015 |
Buspirone in ADHD with ODD.
Topics: Anti-Anxiety Agents; Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Child Behavior | 1995 |
Buspirone for aggression.
Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Child Behavior Disorder | 1991 |
Buspirone for attention deficit hyperactivity disorder?
Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Dose-Response Relationship, Drug; Humans; | 1990 |