Page last updated: 2024-10-24

buspirone and ADDH

buspirone has been researched along with ADDH in 12 studies

Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
buspirone : An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.

Research Excerpts

ExcerptRelevanceReference
"Buspirone has a favorable side-effects profile."2.75Buspirone versus methylphenidate in the treatment of attention deficit hyperactivity disorder: a double-blind and randomized trial. ( Amini, H; Davari-Ashtiani, R; Mazhabdar, H; Razjouyan, K; Shahrbabaki, ME, 2010)
"Methylphenidate as a psycho stimulant drug has been prescribed in neuropsychiatric disorders to increase cognition and attention therefore is a medication of choice for attention-deficit/hyperactivity disorder however long-term administration of central nervous system stimulant produces tolerance on cognitive behavior."1.42Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration. ( Alam, N; Khan, SS; Najam, R, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Haleem, DJ1
Salman, T1
Nawaz, S1
Ikram, H1
Yüce, M1
Karabekiroğlu, K1
Say, GN1
Müjdeci, M1
Oran, M1
Alam, N1
Najam, R1
Khan, SS1
Matsui, Y1
Matsunaga, S1
Matsuda, Y1
Kishi, T1
Iwata, N1
Davari-Ashtiani, R1
Shahrbabaki, ME1
Razjouyan, K1
Amini, H1
Mazhabdar, H1
Sutherland, SM1
Adler, LA1
Chen, C1
Smith, MD1
Feltner, DE1
Mohammadi, MR1
Hafezi, P1
Galeiha, A1
Hajiaghaee, R1
Akhondzadeh, S1
Niederhofer, H1
Gross, MD1
Malhotra, S1
Santosh, PJ1
Quiason, N1
Ward, D1
Kitchen, T1
Balon, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Eight-Week, Double-Blind, 3-Arm Parallel, Placebo-Controlled, Randomized Efficacy And Safety Trial Of Atomoxetine, Atomoxetine Plus Buspirone, And Placebo In Adults With Attention Deficit Hyperactivity Disorder[NCT00174226]Phase 2241 participants (Actual)Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for buspirone and ADDH

ArticleYear
Azapirones for Attention Deficit Hyperactivity Disorder: A Systematic Review.
    Pharmacopsychiatry, 2016, Volume: 49, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Humans; Randomized Controlled Trials as To

2016

Trials

5 trials available for buspirone and ADDH

ArticleYear
Buspirone versus methylphenidate in the treatment of attention deficit hyperactivity disorder: a double-blind and randomized trial.
    Child psychiatry and human development, 2010, Volume: 41, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous System Stimulants; Child;

2010
An 8-week, randomized controlled trial of atomoxetine, atomoxetine plus buspirone, or placebo in adults with ADHD.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:4

    Topics: Adult; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Buspirone; Double-B

2012
Buspirone versus methylphenidate in the treatment of children with attention- deficit/ hyperactivity disorder: randomized double-blind study.
    Acta medica Iranica, 2012, Volume: 50, Issue:11

    Topics: Adolescent; Algorithms; Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous Sy

2012
An open trial of buspirone in the treatment of attention-deficit disorder.
    Human psychopharmacology, 2003, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Attention Deficit Disorder with Hyperactivity; Buspirone; Do

2003
An open clinical trial of buspirone in children with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1998, Volume: 37, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Female; Humans; India; Male; Matche

1998

Other Studies

6 other studies available for buspirone and ADDH

ArticleYear
Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens.
    Behavioural brain research, 2022, 02-10, Volume: 418

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Buspirone; Central Nervous System Stimulants

2022
Buspirone use in the treatment of atomoxetine-induced bruxism.
    Journal of child and adolescent psychopharmacology, 2013, Volume: 23, Issue:9

    Topics: Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivi

2013
Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:5

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Avoidance Learning; Buspirone; Central Nervo

2015
Buspirone in ADHD with ODD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Anti-Anxiety Agents; Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Child Behavior

1995
Buspirone for aggression.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:6

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Buspirone; Child; Child Behavior Disorder

1991
Buspirone for attention deficit hyperactivity disorder?
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Buspirone; Dose-Response Relationship, Drug; Humans;

1990