Page last updated: 2024-10-17

bupropion and Weight Gain

bupropion has been researched along with Weight Gain in 43 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"A combination of sustained release (SR) naltrexone (32 mg/day) and bupropion SR (360 mg/day) plus behavioral counseling was evaluated for the treatment of smoking cessation and mitigation of nicotine withdrawal and weight gain."9.14An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects. ( Billes, SK; Dunayevich, E; Erickson, JS; Katz, BB; Oskooilar, N; Tollefson, G; Wilcox, CS, 2010)
"To examine the effectiveness of bupropion in reducing bodyweight gained during treatment with olanzapine."9.12Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial. ( Foust, MS; Gadde, KM; Zhang, W, 2006)
"Studies undertaken in academic settings have shown that bupropion hydrochloride can double the odds of smoking cessation compared with placebo."9.12A double-blind, placebo-controlled, randomized trial of bupropion for smoking cessation in primary care. ( Apolone, G; Clivio, L; Compagnoni, A; Fossati, R; Garattini, S; La Vecchia, C; Mangano, S; Negri, E, 2007)
"To determine whether bupropion SR, in combination with counselling, is effective for smoking cessation in a multi-country study."9.10A multicentre, randomized, double-blind, placebo-controlled, 1-year study of bupropion SR for smoking cessation. ( Hider, A; Hjalmarson, A; Lebargy, F; Sweet, R; Tonstad, S; Townsend, J; Tønnesen, P; Van Spiegel, PI, 2003)
"Treatment with sustained-release bupropion alone or in combination with a nicotine patch resulted in significantly higher long-term rates of smoking cessation than use of either the nicotine patch alone or placebo."9.09A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. ( Baker, TB; Daughton, DM; Doan, K; Fiore, MC; Hughes, AR; Johnston, JA; Jorenby, DE; Leischow, SJ; Muramoto, ML; Nides, MA; Rennard, SI; Smith, SS, 1999)
"In persons who stopped smoking with 7 weeks of bupropion treatment, sustained-release bupropion for 12 months delayed smoking relapse and resulted in less weight gain."9.09Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. a randomized, controlled trial. ( Buist, AS; Durcan, MJ; Gonzales, D; Hays, JT; Hurt, RD; Johnston, JA; Niaura, R; Rigotti, NA; Sachs, DP; White, JD; Wolter, TD, 2001)
"A sustained-release form of bupropion was effective for smoking cessation and was accompanied by reduced weight gain and minimal side effects."9.08A comparison of sustained-release bupropion and placebo for smoking cessation. ( Croghan, IT; Dale, LC; Glover, ED; Glover, PN; Hurt, RD; Johnston, JA; Khayrallah, MA; Offord, KP; Sachs, DP; Schroeder, DR; Sullivan, CR; Sullivan, PM, 1997)
" Melatonin, liraglutide, and naltrexone/bupropion are examples of drugs with different mechanisms of action that have favorable effects on obesity or medication-related weight gain."8.91Melatonin, Liraglutide, and Naltrexone/Bupropion for the Treatment of Obesity and Medication-Related Weight Gain. ( Howland, RH, 2015)
" [symbol: see text]Bupropion (Zyban-GlaxoWellcome) has recently been licensed "as an aid to smoking cessation in combination with motivational support"."8.80Bupropion to aid smoking cessation. ( , 2000)
" This investigation was an open label study of naltrexone hydrochloride (25 mg/day) in combination with sustained-release (SR) bupropion hydrochloride (300 mg/day) for smoking cessation and minimization of post-quit weight gain in weight-concerned smokers."7.74A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain. ( Leary, V; Meandzija, B; O'Malley, SS; Salovey, P; Toll, BA; Wu, R, 2008)
"Insulin resistance was also assessed at the end."6.71Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine. ( Alvarez, F; Botella-Carretero, JI; Cantarero, M; Escobar-Morreale, HF; García, G; Martín, I; Valero, AM; Varela, C, 2004)
"A combination of sustained release (SR) naltrexone (32 mg/day) and bupropion SR (360 mg/day) plus behavioral counseling was evaluated for the treatment of smoking cessation and mitigation of nicotine withdrawal and weight gain."5.14An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects. ( Billes, SK; Dunayevich, E; Erickson, JS; Katz, BB; Oskooilar, N; Tollefson, G; Wilcox, CS, 2010)
"To examine the effectiveness of bupropion in reducing bodyweight gained during treatment with olanzapine."5.12Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial. ( Foust, MS; Gadde, KM; Zhang, W, 2006)
"This study evaluated the ability of polymorphisms in five candidate genes to predict weight gain among patients taking bupropion or placebo in a smoking cessation trial."5.12No evidence for a major role of polymorphisms during bupropion treatment. ( Allison, DB; Berrettini, WH; Hu, J; Lerman, C; Pinto, A; Redden, DT; Restine, SL; Shields, PG, 2006)
"Studies undertaken in academic settings have shown that bupropion hydrochloride can double the odds of smoking cessation compared with placebo."5.12A double-blind, placebo-controlled, randomized trial of bupropion for smoking cessation in primary care. ( Apolone, G; Clivio, L; Compagnoni, A; Fossati, R; Garattini, S; La Vecchia, C; Mangano, S; Negri, E, 2007)
"Sustained-release bupropion is efficacious as an aid to smoking cessation in European smokers."5.11Efficacy of bupropion and predictors of successful outcome in a sample of French smokers: a randomized placebo-controlled trial. ( Aubin, HJ; Berlin, I; Bidaut-Mazel, C; Chemali-Hudry, J; Lagrue, G; Lebargy, F, 2004)
"To determine whether bupropion SR, in combination with counselling, is effective for smoking cessation in a multi-country study."5.10A multicentre, randomized, double-blind, placebo-controlled, 1-year study of bupropion SR for smoking cessation. ( Hider, A; Hjalmarson, A; Lebargy, F; Sweet, R; Tonstad, S; Townsend, J; Tønnesen, P; Van Spiegel, PI, 2003)
"Treatment with sustained-release bupropion alone or in combination with a nicotine patch resulted in significantly higher long-term rates of smoking cessation than use of either the nicotine patch alone or placebo."5.09A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. ( Baker, TB; Daughton, DM; Doan, K; Fiore, MC; Hughes, AR; Johnston, JA; Jorenby, DE; Leischow, SJ; Muramoto, ML; Nides, MA; Rennard, SI; Smith, SS, 1999)
"In persons who stopped smoking with 7 weeks of bupropion treatment, sustained-release bupropion for 12 months delayed smoking relapse and resulted in less weight gain."5.09Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. a randomized, controlled trial. ( Buist, AS; Durcan, MJ; Gonzales, D; Hays, JT; Hurt, RD; Johnston, JA; Niaura, R; Rigotti, NA; Sachs, DP; White, JD; Wolter, TD, 2001)
"A sustained-release form of bupropion was effective for smoking cessation and was accompanied by reduced weight gain and minimal side effects."5.08A comparison of sustained-release bupropion and placebo for smoking cessation. ( Croghan, IT; Dale, LC; Glover, ED; Glover, PN; Hurt, RD; Johnston, JA; Khayrallah, MA; Offord, KP; Sachs, DP; Schroeder, DR; Sullivan, CR; Sullivan, PM, 1997)
" This paper reviews the prevalence of sexual dysfunction, weight gain and emotional detachment during SSRI treatment, the profile of bupropion for each of these events and the ability of bupropion to reverse them."4.84Review: Bupropion and SSRI-induced side effects. ( Demyttenaere, K; Jaspers, L, 2008)
" Bupropion is less likely than other antidepressants to cause weight gain and sexual dysfunction, the 2 side effects that are of greatest concern to patients and that have the greatest impact on long-term compliance."4.82Why isn't bupropion the most frequently prescribed antidepressant? ( Attiullah, N; Baymiller, S; Berlowitz, SL; Boland, RJ; Chelminski, I; Friedman, M; Posternak, MA; Rahman, S; Singer, S; Uy, KK; Zimmerman, M, 2005)
" [symbol: see text]Bupropion (Zyban-GlaxoWellcome) has recently been licensed "as an aid to smoking cessation in combination with motivational support"."4.80Bupropion to aid smoking cessation. ( , 2000)
"While patients using bupropion gained slightly less weight compared to those using varenicline, type of smoking cessation medication was not a significant predictor of weight change in the multivariate linear regression model."3.83Comparative Effectiveness of Smoking Cessation Medications to Attenuate Weight Gain Following Cessation. ( Abughosh, S; Chen, H; Essien, EJ; Johnson, ML; Peters, RJ; Wang, X; Yang, M, 2016)
"Compared with citalopram, in models adjusted for sociodemographic and clinical features, significantly decreased rate of weight gain was observed among individuals treated with bupropion (β [SE]: -0."3.80An electronic health records study of long-term weight gain following antidepressant use. ( Blumenthal, SR; Castro, VM; Churchill, SE; Clements, CC; Erb, JL; Fava, M; Kohane, IS; Murphy, SN; Perlis, RH; Rosenfield, HR; Smoller, JW; Weilburg, JB, 2014)
" Anxiety levels, which are greater in the first few weeks after cessation, do not explain weight variation, which is more related to the metabolic effects of nicotine rather than to psychological variables."3.74[Weight gain and anxiety levels in recent ex-smokers]. ( Beamonte, A; Gargallo, P; Jiménez-Muro, A; Marqueta, A; Nerín, I, 2007)
" This investigation was an open label study of naltrexone hydrochloride (25 mg/day) in combination with sustained-release (SR) bupropion hydrochloride (300 mg/day) for smoking cessation and minimization of post-quit weight gain in weight-concerned smokers."3.74A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain. ( Leary, V; Meandzija, B; O'Malley, SS; Salovey, P; Toll, BA; Wu, R, 2008)
"Insulin resistance was also assessed at the end."2.71Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine. ( Alvarez, F; Botella-Carretero, JI; Cantarero, M; Escobar-Morreale, HF; García, G; Martín, I; Valero, AM; Varela, C, 2004)
"Weight gain is cited as a primary reason for not trying to quit smoking."2.42Smoking cessation and weight gain. ( Fernández Pinilla, MC; Fernández-Cruz, A; Filozof, C, 2004)
"Anecdotal reports have suggested that the long-term use of selective serotonin reuptake inhibitors (SSRIs) may be associated with significant weight gain, sexual dysfunction, drug interactions, and discontinuation symptoms."2.41Long-term side effects of newer-generation antidepressants: SSRIS, venlafaxine, nefazodone, bupropion, and mirtazapine. ( Gupta, S; Masand, PS, 2002)
"Study data demonstrate that seizure incidence, which is a concern with high-dose IR, is substantially lower with the new SR formulation."2.40Bupropion sustained release: side effect profile. ( Settle, EC, 1998)
"Despite the superior side effect profile of the newer antidepressants over the tricyclics and monoamine oxidase inhibitors, all newer antidepressants are associated with a wide array of side effects."1.31The pharmacologic management of SSRI-induced side effects: a survey of psychiatrists. ( Dording, CM; Fava, M; Gordon, J; Kornbluh, R; Mischoulon, D; Nierenberg, AA; Petersen, TJ; Rosenbaum, JE, 2002)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (16.28)18.2507
2000's27 (62.79)29.6817
2010's9 (20.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sobell, MB1
Peterson, AL1
Sobell, LC1
Brundige, A1
Hunter, CM2
Goodie, JL1
Agrawal, S1
Hrysko-Mullen, AS1
Isler, WC1
Hou, YC1
Lai, CH1
Blumenthal, SR1
Castro, VM1
Clements, CC1
Rosenfield, HR1
Murphy, SN1
Fava, M2
Weilburg, JB1
Erb, JL1
Churchill, SE1
Kohane, IS1
Smoller, JW1
Perlis, RH1
Howland, RH1
Yang, M1
Chen, H1
Johnson, ML1
Essien, EJ1
Peters, RJ1
Wang, X1
Abughosh, S1
Igel, LI1
Kumar, RB1
Saunders, KH1
Aronne, LJ1
Kapoor, S1
Iñiguez, SD1
Warren, BL1
Parise, EM1
Alcantara, LF1
Schuh, B1
Maffeo, ML1
Manojlovic, Z1
Bolaños-Guzmán, CA1
Etter, JF1
Huguelet, P1
Perneger, TV1
Cornuz, J1
Nanchen, D1
Willi, C1
Peytremann-Bridevaux, I1
Burnand, B1
Walther, MR1
Wilcox, CS1
Oskooilar, N1
Erickson, JS1
Billes, SK1
Katz, BB1
Tollefson, G1
Dunayevich, E1
Kaplan, LM1
Levine, MD1
Cheng, Y1
Kalarchian, MA1
Perkins, KA1
Marcus, MD1
Dording, CM1
Mischoulon, D1
Petersen, TJ1
Kornbluh, R1
Gordon, J1
Nierenberg, AA1
Rosenbaum, JE1
Masand, PS1
Gupta, S1
Tønnesen, P1
Tonstad, S2
Hjalmarson, A1
Lebargy, F2
Van Spiegel, PI1
Hider, A1
Sweet, R1
Townsend, J1
Botella-Carretero, JI1
Escobar-Morreale, HF1
Martín, I1
Valero, AM1
Alvarez, F1
García, G1
Varela, C1
Cantarero, M1
Filozof, C1
Fernández Pinilla, MC1
Fernández-Cruz, A1
Johnston, JA4
Aubin, HJ1
Berlin, I1
Bidaut-Mazel, C1
Chemali-Hudry, J1
Lagrue, G1
Gołecki, M1
Zimmerman, M1
Posternak, MA1
Attiullah, N1
Friedman, M1
Boland, RJ1
Baymiller, S1
Berlowitz, SL1
Rahman, S1
Uy, KK1
Singer, S1
Chelminski, I1
Menaster, MJ1
Gadde, KM1
Zhang, W1
Foust, MS1
Hu, J1
Redden, DT1
Berrettini, WH1
Shields, PG1
Restine, SL1
Pinto, A1
Lerman, C1
Allison, DB1
Nerín, I1
Beamonte, A1
Gargallo, P1
Jiménez-Muro, A1
Marqueta, A1
Ramseier, CA1
Bornstein, MM1
Saxer, UP1
Klingler, K1
Walter, C1
Toll, BA1
Leary, V1
Wu, R1
Salovey, P1
Meandzija, B1
O'Malley, SS1
Fossati, R1
Apolone, G1
Negri, E1
Compagnoni, A1
La Vecchia, C1
Mangano, S1
Clivio, L1
Garattini, S1
Demyttenaere, K1
Jaspers, L1
Lief, HI1
Hurt, RD2
Sachs, DP2
Glover, ED1
Offord, KP1
Dale, LC1
Khayrallah, MA1
Schroeder, DR1
Glover, PN1
Sullivan, CR1
Croghan, IT1
Sullivan, PM1
McAfee, T1
France, E1
Settle, EC1
Jorenby, DE1
Leischow, SJ1
Nides, MA1
Rennard, SI1
Hughes, AR1
Smith, SS1
Muramoto, ML1
Daughton, DM1
Doan, K1
Fiore, MC1
Baker, TB1
Haustein, KO2
Hays, JT1
Rigotti, NA1
Niaura, R1
Gonzales, D1
Durcan, MJ1
Wolter, TD1
Buist, AS1
White, JD1
Croft, H1
Houser, TL1
Jamerson, BD1
Leadbetter, R1
Bolden-Watson, C1
Donahue, R1
Metz, A1
Workman, EA1
Short, DD1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of a High Eicosapentaenoic Acid Multinutrient Supplement on Measures of Stress, Anxiety and Depression in Young Adults: a Randomised, Double-blind, Placebo-controlled Trial.[NCT04844034]94 participants (Anticipated)Interventional2022-04-19Recruiting
Effects of a Tissue Selective Estrogen Complex (TESC) on Depression and the Neural Reward System in the Perimenopause[NCT03740009]Phase 420 participants (Actual)Interventional2019-01-02Completed
WhatsApp Embedded in Routine Service Delivery for Smoking Cessation: Effects on Success Rates in a Randomized Controlled Study[NCT03714971]127 participants (Actual)Interventional2017-03-01Completed
Naltrexone & Bupropion to Stop Smoking With Less Weight Gain[NCT00129246]Phase 1/Phase 240 participants (Actual)Interventional2004-12-31Completed
Phase II Randomized, Double-Blind Trial of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation[NCT00419731]Phase 2/Phase 3120 participants (Anticipated)Interventional2006-11-30Recruiting
A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Multicenter, Dose-Ranging Study of 100 or 250 μg of TA-NIC to Assess the Efficacy and Safety of the Vaccine as an Aid to Smoking Cessation[NCT00633321]Phase 2522 participants (Anticipated)Interventional2007-05-31Completed
The STOP Study: Real World Effectiveness of Zyban Treatment in a Clinical Population[NCT01015170]Phase 4454 participants (Actual)Interventional2009-10-31Completed
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence[NCT00749658]Phase 2/Phase 3121 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Frontostriatal Reactivity to Reward During MID fMRI Task

"The primary outcome measure is functional magnetic resonance imaging (fMRI) data collected during a Monetary Incentive Delay (MID) Task. All participants will complete the fMRI Monetary Incentive Delay (MID) task at baseline and at 3 weeks. During the task, participants need to select the correct response during win and lose conditions by pressing a button on a button box in the MRI. Participant's blood-oxygen-level dependent (BOLD) activation response (A measurement of oxygen level that is released to neurons since areas of the brain that are thought to be more active or involved in certain tasks require more oxygen to perform the tasks.) is measured while they performed the task in MRI scanner." (NCT03740009)
Timeframe: Baseline to 3 weeks

Interventionpercent signal change (Mean)
Caudate BaselineCaudate PosttreatmentNucleus Accumbens BaselineNucleus Accumbens PosttreatmentPutamen BaselinePutamen Posttreatment
Perimenopausal Women, Depressed.0704.0475.0623.0280.0399.0408

Depressive Symptoms as Measured by the MASQ-AD

The second primary outcome measure uses the Mood and Anxiety Symptoms Questionnaire - Anhedonic Depression Scale (MASQ-AD) to examine symptom change. All participants will complete the MASQ-AD at each study visit, which measures their current symptoms of depression and anxiety. Scores range from 22 to 110 with lower scores reflecting a better outcome. (NCT03740009)
Timeframe: Baseline, week 2, week 3, week 4 (post treatment)

Interventionscore on a scale (Mean)
Baseline Week 1Week 2Week 3Post Treatment Week 4
Perimenopausal Women, Depressed72.162.457.254.5

Point Prevalence Abstinence

Point prevalence abstinence is defined as the number of patients reporting point prevalence abstinence over the last 7 days. (NCT00129246)
Timeframe: Week 6

Interventionparticipants (Number)
Bupropion Only8
Naltrexone +Bupropion8

Smoking Cessation

Smoking cessation is defined as the number of patients that displayed continuous 6-week abstinence from the quit date. (NCT00129246)
Timeframe: Week 6

Interventionparticipants (Number)
Bupropion Only6
Naltrexone +Bupropion6

Weight Gain

Weight gain for for the entire sample in pounds at 6 weeks. (NCT00129246)
Timeframe: Week 6

Interventionlbs (Mean)
Bupropion Only1.25
Naltrexone +Bupropion0.28

Weight Gain Abstinent Participants

Weight gain (in pounds) for the patients that were continuously abstinent at 6 weeks. (NCT00129246)
Timeframe: Week 6

Interventionlbs (Mean)
Bupropion Only3.17
Naltrexone +Bupropion1.67

7-day Point Prevalence of Smoking Abstinence

"Number of participants who report Not Smoking (not even a puff) in past 7 days when asked at week 8" (NCT01015170)
Timeframe: End of Treatment (8 weeks after Zyban start date)

Interventionparticipants (Number)
Still smokingQuit smoking
Nicotine Replacement & Behavioural Support109106

Reviews

12 reviews available for bupropion and Weight Gain

ArticleYear
Melatonin, Liraglutide, and Naltrexone/Bupropion for the Treatment of Obesity and Medication-Related Weight Gain.
    Journal of psychosocial nursing and mental health services, 2015, Volume: 53, Issue:6

    Topics: Anti-Obesity Agents; Bupropion; Drug Combinations; Humans; Liraglutide; Melatonin; Naltrexone; Obesi

2015
Practical Use of Pharmacotherapy for Obesity.
    Gastroenterology, 2017, Volume: 152, Issue:7

    Topics: Androgens; Anti-Obesity Agents; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents

2017
Pharmacologic therapies for obesity.
    Gastroenterology clinics of North America, 2010, Volume: 39, Issue:1

    Topics: Anti-Obesity Agents; Appetite Depressants; Bariatric Surgery; Benzazepines; Bupropion; Cyclobutanes;

2010
Long-term side effects of newer-generation antidepressants: SSRIS, venlafaxine, nefazodone, bupropion, and mirtazapine.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2002, Volume: 14, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Drug Interactions; Humans; Mians

2002
Long-term side effects of newer-generation antidepressants: SSRIS, venlafaxine, nefazodone, bupropion, and mirtazapine.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2002, Volume: 14, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Drug Interactions; Humans; Mians

2002
Long-term side effects of newer-generation antidepressants: SSRIS, venlafaxine, nefazodone, bupropion, and mirtazapine.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2002, Volume: 14, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Drug Interactions; Humans; Mians

2002
Long-term side effects of newer-generation antidepressants: SSRIS, venlafaxine, nefazodone, bupropion, and mirtazapine.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2002, Volume: 14, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Drug Interactions; Humans; Mians

2002
Smoking cessation and weight gain.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2004, Volume: 5, Issue:2

    Topics: Body Composition; Bupropion; Cardiovascular Diseases; Dopamine Uptake Inhibitors; Female; Humans; In

2004
Does bupropion have advantages over other medical therapies in the cessation of smoking?
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:4

    Topics: Administration, Cutaneous; Aged; Bupropion; Delayed-Action Preparations; Dopamine Uptake Inhibitors;

2004
[Bupropion SR for the therapy of tobacco dependence].
    Pneumonologia i alergologia polska, 2004, Volume: 72, Issue:3-4

    Topics: Bupropion; Delayed-Action Preparations; Dopamine Uptake Inhibitors; Humans; Tobacco Use Disorder; Tr

2004
Why isn't bupropion the most frequently prescribed antidepressant?
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:5

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Antidepressive Agents, Second-Generation; Bupropion;

2005
Review: Bupropion and SSRI-induced side effects.
    Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:7

    Topics: Affective Symptoms; Bupropion; Depression; Dopamine Uptake Inhibitors; Drug Interactions; Drug Thera

2008
Bupropion sustained release: side effect profile.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 4

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Delayed-Actio

1998
Pharmacotherapy of nicotine dependence.
    International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:6

    Topics: Bupropion; Drug Interactions; Humans; Prognosis; Tobacco Use Disorder; Weight Gain

2000
Bupropion to aid smoking cessation.
    Drug and therapeutics bulletin, 2000, Volume: 38, Issue:10

    Topics: Adult; Aged; Bupropion; Chemotherapy, Adjuvant; Delayed-Action Preparations; Dopamine Uptake Inhibit

2000

Trials

16 trials available for bupropion and Weight Gain

ArticleYear
Reducing alcohol consumption to minimize weight gain and facilitate smoking cessation among military beneficiaries.
    Addictive behaviors, 2017, Volume: 75

    Topics: Adult; Alcohol Drinking; Bupropion; Dopamine Uptake Inhibitors; Energy Intake; Female; Humans; Male;

2017
Nicotine gum treatment before smoking cessation: a randomized trial.
    Archives of internal medicine, 2009, Jun-08, Volume: 169, Issue:11

    Topics: Bupropion; Chewing Gum; Humans; Nicotine; Polymethacrylic Acids; Polyvinyls; Smoking Cessation; Toba

2009
An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects.
    Addictive behaviors, 2010, Volume: 35, Issue:3

    Topics: Adult; Bupropion; Cotinine; Counseling; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Femal

2010
Dietary intake after smoking cessation among weight-concerned women smokers.
    Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2012, Volume: 26, Issue:4

    Topics: Body Weight; Bupropion; Diet; Eating; Female; Humans; Smoking; Smoking Cessation; Weight Gain

2012
A multicentre, randomized, double-blind, placebo-controlled, 1-year study of bupropion SR for smoking cessation.
    Journal of internal medicine, 2003, Volume: 254, Issue:2

    Topics: Adult; Bupropion; Delayed-Action Preparations; Dopamine Uptake Inhibitors; Double-Blind Method; Fema

2003
Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:3

    Topics: Administration, Cutaneous; Adult; Aging; Blood Pressure; Bupropion; Cardiovascular Diseases; Diastol

2004
Efficacy of bupropion and predictors of successful outcome in a sample of French smokers: a randomized placebo-controlled trial.
    Addiction (Abingdon, England), 2004, Volume: 99, Issue:9

    Topics: Adult; Alcohol Drinking; Bupropion; Dopamine Uptake Inhibitors; Double-Blind Method; Female; France;

2004
Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Buprop

2006
No evidence for a major role of polymorphisms during bupropion treatment.
    Obesity (Silver Spring, Md.), 2006, Volume: 14, Issue:11

    Topics: Adult; Bupropion; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Genetic Predisposition to

2006
A double-blind, placebo-controlled, randomized trial of bupropion for smoking cessation in primary care.
    Archives of internal medicine, 2007, Sep-10, Volume: 167, Issue:16

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Double-Blin

2007
A comparison of sustained-release bupropion and placebo for smoking cessation.
    The New England journal of medicine, 1997, Oct-23, Volume: 337, Issue:17

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Depression;

1997
A comparison of sustained-release bupropion and placebo for smoking cessation.
    The New England journal of medicine, 1997, Oct-23, Volume: 337, Issue:17

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Depression;

1997
A comparison of sustained-release bupropion and placebo for smoking cessation.
    The New England journal of medicine, 1997, Oct-23, Volume: 337, Issue:17

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Depression;

1997
A comparison of sustained-release bupropion and placebo for smoking cessation.
    The New England journal of medicine, 1997, Oct-23, Volume: 337, Issue:17

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Depression;

1997
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
    The New England journal of medicine, 1999, Mar-04, Volume: 340, Issue:9

    Topics: Administration, Cutaneous; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Actio

1999
[Antidepressive drug against nicotine. A method for smoking cessation].
    MMW Fortschritte der Medizin, 2000, Dec-14, Volume: 142, Issue:51-52

    Topics: Administration, Cutaneous; Bupropion; Chewing Gum; Delayed-Action Preparations; Drug Administration

2000
Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. a randomized, controlled trial.
    Annals of internal medicine, 2001, Sep-18, Volume: 135, Issue:6

    Topics: Adult; Bupropion; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Age

2001
Summaries for patients. Bupropion to prevent relapse in people who quit cigarette smoking.
    Annals of internal medicine, 2001, Sep-18, Volume: 135, Issue:6

    Topics: Adult; Bupropion; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Patient Compliance

2001
Effect on body weight of bupropion sustained-release in patients with major depression treated for 52 weeks.
    Clinical therapeutics, 2002, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Body Mass Index; Bupropion; Delay

2002

Other Studies

15 other studies available for bupropion and Weight Gain

ArticleYear
Bupropion-related weight gain in a fresh depression patient.
    The Journal of neuropsychiatry and clinical neurosciences, 2014, Apr-01, Volume: 26, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Body Mass Index; Bupropion; Depressive Disorder, Major; Fe

2014
An electronic health records study of long-term weight gain following antidepressant use.
    JAMA psychiatry, 2014, Volume: 71, Issue:8

    Topics: Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bo

2014
Comparative Effectiveness of Smoking Cessation Medications to Attenuate Weight Gain Following Cessation.
    Substance use & misuse, 2016, Volume: 51, Issue:5

    Topics: Adult; Bupropion; Female; Humans; Male; Middle Aged; Retrospective Studies; Smoking Cessation; Tobac

2016
Strategies to control antipsychotic-induced weight gain.
    Psychoneuroendocrinology, 2008, Volume: 33, Issue:8

    Topics: Anti-Obesity Agents; Antipsychotic Agents; Awareness; Body Weight; Bupropion; Clinical Competence; F

2008
Nicotine exposure during adolescence induces a depression-like state in adulthood.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:6

    Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Anxiety; Bupropion; Cholinergic Agents; De

2009
[Preventing weight gain in smoking cessation: there is no miracle solution].
    Revue medicale suisse, 2009, Aug-05, Volume: 5, Issue:212

    Topics: Adult; Bupropion; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Female; Fluoxetine; Humans;

2009
The pharmacologic management of SSRI-induced side effects: a survey of psychiatrists.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2002, Volume: 14, Issue:3

    Topics: Akathisia, Drug-Induced; Antidepressive Agents, Second-Generation; Bupropion; Critical Pathways; Dat

2002
Weight gain, sexual dysfunction, and bupropion.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:10

    Topics: Ambulatory Care; Bupropion; Delayed-Action Preparations; Depressive Disorder; Drug Labeling; Humans;

2005
[Weight gain and anxiety levels in recent ex-smokers].
    Archivos de bronconeumologia, 2007, Volume: 43, Issue:1

    Topics: Adult; Anxiety; Basal Metabolism; Breath Tests; Bupropion; Carbon Monoxide; Chewing Gum; Feeding Beh

2007
[Tobacco use prevention and cessation in the dental practice].
    Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 2007, Volume: 117, Issue:3

    Topics: Behavior Therapy; Benzazepines; Bupropion; Dentist-Patient Relations; Health Plan Implementation; Hu

2007
A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain.
    Addictive behaviors, 2008, Volume: 33, Issue:1

    Topics: Adult; Bupropion; Case-Control Studies; Combined Modality Therapy; Dopamine Uptake Inhibitors; Drug

2008
A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain.
    Addictive behaviors, 2008, Volume: 33, Issue:1

    Topics: Adult; Bupropion; Case-Control Studies; Combined Modality Therapy; Dopamine Uptake Inhibitors; Drug

2008
A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain.
    Addictive behaviors, 2008, Volume: 33, Issue:1

    Topics: Adult; Bupropion; Case-Control Studies; Combined Modality Therapy; Dopamine Uptake Inhibitors; Drug

2008
A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain.
    Addictive behaviors, 2008, Volume: 33, Issue:1

    Topics: Adult; Bupropion; Case-Control Studies; Combined Modality Therapy; Dopamine Uptake Inhibitors; Drug

2008
Bupropion treatment of depression to assist smoking cessation.
    The American journal of psychiatry, 1996, Volume: 153, Issue:3

    Topics: Bupropion; Comorbidity; Depressive Disorder; Female; Humans; Smoking; Smoking Cessation; Smoking Pre

1996
Sustained-release bupropion for smoking cessation.
    The New England journal of medicine, 1998, Feb-26, Volume: 338, Issue:9

    Topics: Bupropion; Dose-Response Relationship, Drug; Smoking Cessation; Weight Gain

1998
Antidepressant drug helps smoking cessation.
    Harvard heart letter : from Harvard Medical School, 1998, Volume: 8, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Humans; Smoking Cessation; Weight Gain

1998
Bupropion-induced carbohydrate craving and weight gain.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Adult; Bupropion; Depressive Disorder; Dietary Carbohydrates; Feeding and Eating Disorders; Humans;

1992