bupropion has been researched along with Status Epilepticus in 8 studies
Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 5.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
| "Bupropion is a monocyclic antidepressant in the aminoketone class, structurally related to amphetamines." | 5.42 | Bupropion Overdose Presenting as Status Epilepticus in an Infant. ( Morgan, R; Patterson, AL; Rivas-Coppola, MS; Wheless, JW, 2015) |
| "However, the seizure threshold may be influenced by psychotropic drugs." | 5.37 | Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion. ( Dersch, R; Voderholzer, U; Zwernemann, S, 2011) |
| "Bupropion overdose commonly causes generalized seizures and central nervous system depression." | 3.79 | Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. ( Al-Abri, SA; Benowitz, NL; Hayashi, S; Olson, KR; Orengo, JP; Thoren, KL, 2013) |
| "Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 1.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
| "Bupropion is a monocyclic antidepressant in the aminoketone class, structurally related to amphetamines." | 1.42 | Bupropion Overdose Presenting as Status Epilepticus in an Infant. ( Morgan, R; Patterson, AL; Rivas-Coppola, MS; Wheless, JW, 2015) |
| "However, the seizure threshold may be influenced by psychotropic drugs." | 1.37 | Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion. ( Dersch, R; Voderholzer, U; Zwernemann, S, 2011) |
| "Diazepam treatment alone and before cocaine overdose did not interfere with catalase activity." | 1.33 | Cocaine alters catalase activity in prefrontal cortex and striatum of mice. ( Aguiar, LM; de Sousa, FC; de Vasconcelos, SM; dos Santos, RS; Lima, VT; Macêdo, DS; Viana, GS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Robinson, S | 1 |
| Al-Abri, SA | 1 |
| Orengo, JP | 1 |
| Hayashi, S | 1 |
| Thoren, KL | 1 |
| Benowitz, NL | 1 |
| Olson, KR | 1 |
| Rivas-Coppola, MS | 1 |
| Patterson, AL | 1 |
| Morgan, R | 1 |
| Wheless, JW | 1 |
| Heise, CW | 1 |
| Skolnik, AB | 1 |
| Raschke, RA | 1 |
| Owen-Reece, H | 1 |
| Graeme, KA | 1 |
| Skripuletz, T | 1 |
| Garde, N | 1 |
| Vidal, C | 1 |
| Mueller-Vahl, H | 1 |
| Dengler, R | 1 |
| Weissenborn, K | 1 |
| Dersch, R | 1 |
| Zwernemann, S | 1 |
| Voderholzer, U | 1 |
| Chao, CT | 1 |
| Wu, VC | 1 |
| Wang, WJ | 1 |
| Macêdo, DS | 1 |
| de Vasconcelos, SM | 1 |
| dos Santos, RS | 1 |
| Aguiar, LM | 1 |
| Lima, VT | 1 |
| Viana, GS | 1 |
| de Sousa, FC | 1 |
8 other studies available for bupropion and Status Epilepticus
| Article | Year |
|---|---|
Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Drug Overdose; Fema | 2022 |
Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxins; Drug Overdose; Electrocard | 2013 |
Bupropion Overdose Presenting as Status Epilepticus in an Infant.
Topics: Antidepressive Agents, Second-Generation; Brain; Bupropion; Diagnosis, Differential; Drug Overdose; | 2015 |
Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrane Oxygenation.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Arizona; Bupropion; Combined Modality Therapy; | 2016 |
Bupropion-induced status epilepticus and retrograde amnesia.
Topics: Amnesia, Retrograde; Bupropion; Dopamine Uptake Inhibitors; Humans; Male; Middle Aged; Status Epilep | 2010 |
Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion.
Topics: Adrenergic Uptake Inhibitors; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupr | 2011 |
Charcoal hemoperfusion for bupropion overdose with ventricular tachycardia and status epilepticus.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Charcoal; Drug Overdose; Electrocar | 2012 |
Cocaine alters catalase activity in prefrontal cortex and striatum of mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Bupropion; Catalase; Catecholamines; Cocaine | 2005 |