bupropion has been researched along with Parkinson Disease in 11 studies
Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a 57-year-old woman, diagnosed with Parkinson's disease, whose panic disorder showed marked improvement after introduction of bupropion, a norepinephrine-dopamine reuptake inhibitor." | 7.74 | Treatment of panic disorder with bupropion in a patient with Parkinson's disease. ( Bäcker, A; Gebhardt, S; Krieg, JC; Röttgers, H; Schu, U, 2008) |
| "The role of dopamine agonists in the treatment of depression is still being explored because of no sufficient number of controlled studies in this area." | 5.36 | Bupropion as the treatment of choice in depression associated with Parkinson's disease and it's various treatments. ( Durst, R; Raskin, S, 2010) |
| "Bupropion has a unique mechanism of action: inhibition of the presynaptic reuptake of dopamine in addition to noradrenergic activity." | 5.31 | [Successful treatment of depression in a Parkinson disease patient with bupropion]. ( Leentjens, AF; Verhey, FR; Vreeling, FW, 2000) |
| "We report on a 57-year-old woman, diagnosed with Parkinson's disease, whose panic disorder showed marked improvement after introduction of bupropion, a norepinephrine-dopamine reuptake inhibitor." | 3.74 | Treatment of panic disorder with bupropion in a patient with Parkinson's disease. ( Bäcker, A; Gebhardt, S; Krieg, JC; Röttgers, H; Schu, U, 2008) |
| "Selegiline is a selective monoamine oxidase inhibitor used in the treatment of Parkinson's disease." | 2.40 | Retrospective study of selegiline-antidepressant drug interactions and a review of the literature. ( Alexander, B; Ritter, JL, 1997) |
| "The role of dopamine agonists in the treatment of depression is still being explored because of no sufficient number of controlled studies in this area." | 1.36 | Bupropion as the treatment of choice in depression associated with Parkinson's disease and it's various treatments. ( Durst, R; Raskin, S, 2010) |
| "Bupropion has a unique mechanism of action: inhibition of the presynaptic reuptake of dopamine in addition to noradrenergic activity." | 1.31 | [Successful treatment of depression in a Parkinson disease patient with bupropion]. ( Leentjens, AF; Verhey, FR; Vreeling, FW, 2000) |
| "Bupropion is an antidepressant, thought to be an indirect dopaminergic agonist." | 1.27 | Bupropion in Parkinson's disease. ( Goetz, CG; Klawans, HL; Tanner, CM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Vismara, M | 1 |
| Benatti, B | 1 |
| Nicolini, G | 1 |
| Cova, I | 1 |
| Monfrini, E | 1 |
| Di Fonzo, A | 1 |
| Fetoni, V | 1 |
| Viganò, CA | 1 |
| Priori, A | 1 |
| Dell'Osso, B | 1 |
| Ahn, BJ | 1 |
| Kwon, KY | 1 |
| Gebhardt, S | 1 |
| Röttgers, H | 1 |
| Bäcker, A | 1 |
| Schu, U | 1 |
| Krieg, JC | 1 |
| Raskin, S | 1 |
| Durst, R | 1 |
| Załuska, M | 1 |
| Dyduch, A | 1 |
| Benincasa, D | 1 |
| Pellicano, C | 1 |
| Fanciulli, A | 1 |
| Pontieri, FE | 1 |
| Grandas, F | 1 |
| López-Manzanares, L | 1 |
| Goetz, CG | 1 |
| Tanner, CM | 1 |
| Klawans, HL | 1 |
| Ritter, JL | 1 |
| Alexander, B | 1 |
| Leentjens, AF | 1 |
| Verhey, FR | 1 |
| Vreeling, FW | 1 |
| Liberzon, I | 1 |
| Dequardo, JR | 1 |
| Silk, KR | 1 |
2 reviews available for bupropion and Parkinson Disease
| Article | Year |
|---|---|
Clinical uses of Bupropion in patients with Parkinson's disease and comorbid depressive or neuropsychiatric symptoms: a scoping review.
Topics: Antidepressive Agents; Apathy; Bupropion; Dopamine; Humans; Parkinson Disease | 2022 |
Retrospective study of selegiline-antidepressant drug interactions and a review of the literature.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Bu | 1997 |
9 other studies available for bupropion and Parkinson Disease
| Article | Year |
|---|---|
Elderly woman presenting with unusual propriospinal myoclonus triggered by drug-induced nausea and vomiting.
Topics: Aged, 80 and over; Alzheimer Disease; Bupropion; Dopamine Agents; Dopamine Uptake Inhibitors; Female | 2018 |
Treatment of panic disorder with bupropion in a patient with Parkinson's disease.
Topics: Bupropion; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Female; Humans; Middle Aged; Pani | 2008 |
Bupropion as the treatment of choice in depression associated with Parkinson's disease and it's various treatments.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Depression; Dopamine Uptake Inhibitors; Humans; | 2010 |
Bupropion in the treatment of depression in Parkinson's disease.
Topics: Aged; Antidepressive Agents, Second-Generation; Brain; Bupropion; Depressive Disorder; Female; Human | 2011 |
Bupropion abates dopamine agonist-mediated compulsive behaviors in Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Bupropion; Compulsive Behavior; Dopamine Uptake Inhibitors; Femal | 2011 |
Bupropion-induced parkinsonism.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Depression; Humans; Male; Middle Aged; Parkinso | 2007 |
Bupropion in Parkinson's disease.
Topics: Adult; Aged; Bupropion; Female; Humans; Male; Middle Aged; Parkinson Disease; Propiophenones | 1984 |
[Successful treatment of depression in a Parkinson disease patient with bupropion].
Topics: Aged; Antidepressive Agents, Second-Generation; Bupropion; Depression; Dopamine Uptake Inhibitors; F | 2000 |
Bupropion and delirium.
Topics: Aged; Amantadine; Antidepressive Agents; Bupropion; Delirium; Depressive Disorder; Drug Therapy, Com | 1990 |