Page last updated: 2024-10-17

bupropion and Neuralgia

bupropion has been researched along with Neuralgia in 6 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Bupropion is a specific inhibitor of neuronal noradrenaline reuptake and a weak inhibitor of dopamine reuptake, which shows some promise in the treatment of neuropathic pain."6.46Bupropion for the treatment of neuropathic pain. ( Moradimehr, A; Shah, TH, 2010)
"Drug effects on formalin-induced mechanical allodynia were evaluated for comparison."5.43Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016)
"Forty-one nondepressed patients with neuropathic pain spent 6 weeks in each phase in random order and received identical tablets of 150 mg bupropion SR or placebo."2.70Double-blind, randomized trial of bupropion SR for the treatment of neuropathic pain. ( Davis, B; Semenchuk, MR; Sherman, S, 2001)
"Bupropion is a specific inhibitor of neuronal noradrenaline reuptake and a weak inhibitor of dopamine reuptake, which shows some promise in the treatment of neuropathic pain."2.46Bupropion for the treatment of neuropathic pain. ( Moradimehr, A; Shah, TH, 2010)
"Drug effects on formalin-induced mechanical allodynia were evaluated for comparison."1.43Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016)
"We hypothesized that bupropion inhibits neuropathic pain by increasing noradrenaline and dopamine in the spinal cord."1.42The antihyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain. ( Hoshino, H; Mieda, R; Nakajima, K; Obata, H; Saito, S, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoshino, H1
Obata, H1
Nakajima, K1
Mieda, R1
Saito, S1
Leitl, MD1
Negus, SS1
Hawley, P1
Shah, TH1
Moradimehr, A1
Katz, J1
Pennella-Vaughan, J1
Hetzel, RD1
Kanazi, GE1
Dworkin, RH1
Semenchuk, MR1
Sherman, S1
Davis, B1

Reviews

1 review available for bupropion and Neuralgia

ArticleYear
Bupropion for the treatment of neuropathic pain.
    The American journal of hospice & palliative care, 2010, Volume: 27, Issue:5

    Topics: Analgesics, Non-Narcotic; Bupropion; Chronic Disease; Controlled Clinical Trials as Topic; Dopamine

2010

Trials

2 trials available for bupropion and Neuralgia

ArticleYear
A randomized, placebo-controlled trial of bupropion sustained release in chronic low back pain.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Chronic Disease; Cross-Over Studies; Del

2005
Double-blind, randomized trial of bupropion SR for the treatment of neuropathic pain.
    Neurology, 2001, Nov-13, Volume: 57, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Bupropion; Cross-Over Studies; Delayed-Action Preparations; Dopamine

2001

Other Studies

3 other studies available for bupropion and Neuralgia

ArticleYear
The antihyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Bupropion; Dopamine; Dopamine Uptake Inhibi

2015
Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Animals; Bupropion; Depression; Disease Models, Animal; Dose-Respons

2016
Nontricyclic antidepressants for neuropathic pain #187.
    Journal of palliative medicine, 2009, Volume: 12, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Duloxetine Hydrochloride; Humans

2009