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bupropion and Multiple Sclerosis, Relapsing-Remitting

bupropion has been researched along with Multiple Sclerosis, Relapsing-Remitting in 1 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Multiple Sclerosis, Relapsing-Remitting: The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)

Research Excerpts

ExcerptRelevanceReference
"Improvement of fatigue in patients with multiple sclerosis (MS) who were given bupropion has been previously reported, but scales for lethargy and depression were not used."7.76Open, uncontrolled, nonrandomized, 9-month, off-label use of bupropion to treat fatigue in a single patient with multiple sclerosis. ( De Sarro, G; Gallelli, L; Loiacono, D; Siniscalchi, A; Tolotta, GA, 2010)
"Improvement of fatigue in patients with multiple sclerosis (MS) who were given bupropion has been previously reported, but scales for lethargy and depression were not used."3.76Open, uncontrolled, nonrandomized, 9-month, off-label use of bupropion to treat fatigue in a single patient with multiple sclerosis. ( De Sarro, G; Gallelli, L; Loiacono, D; Siniscalchi, A; Tolotta, GA, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Siniscalchi, A1
Gallelli, L1
Tolotta, GA1
Loiacono, D1
De Sarro, G1

Other Studies

1 other study available for bupropion and Multiple Sclerosis, Relapsing-Remitting

ArticleYear
Open, uncontrolled, nonrandomized, 9-month, off-label use of bupropion to treat fatigue in a single patient with multiple sclerosis.
    Clinical therapeutics, 2010, Volume: 32, Issue:12

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Fatigue; Female; Humans; Middle Aged; Multiple

2010