bupropion has been researched along with Morphine Dependence in 3 studies
Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bupropion was devoid of intrinsic analgesic activity and did not enhance morphine acute analgesia." | 5.48 | Bupropion attenuates morphine tolerance and dependence: Possible role of glutamate, norepinephrine, inflammation, and oxidative stress. ( Barakat, A; Elbadr, MM; Hamdy, MM, 2018) |
| "Bupropion was devoid of intrinsic analgesic activity and did not enhance morphine acute analgesia." | 1.48 | Bupropion attenuates morphine tolerance and dependence: Possible role of glutamate, norepinephrine, inflammation, and oxidative stress. ( Barakat, A; Elbadr, MM; Hamdy, MM, 2018) |
| " Chronic administration of bupropion (2 or 5 mg/kg) during the induction phase (days 1-9) delayed the development of tolerance to the antinociceptive action of morphine and also reversed naloxone- (2 mg/kg) precipitated withdrawal jumps." | 1.32 | Protective effect of bupropion on morphine tolerance and dependence in mice. ( Joshi, D; Kulkarni, SK; Naidu, PS; Singh, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamdy, MM | 1 |
| Elbadr, MM | 1 |
| Barakat, A | 1 |
| Joshi, D | 1 |
| Singh, A | 1 |
| Naidu, PS | 1 |
| Kulkarni, SK | 1 |
| Taraschenko, OD | 1 |
| Panchal, V | 1 |
| Maisonneuve, IM | 1 |
| Glick, SD | 1 |
3 other studies available for bupropion and Morphine Dependence
| Article | Year |
|---|---|
Bupropion attenuates morphine tolerance and dependence: Possible role of glutamate, norepinephrine, inflammation, and oxidative stress.
Topics: Animals; Brain; Bupropion; Dose-Response Relationship, Drug; Drug Tolerance; Glutamic Acid; Glutathi | 2018 |
Protective effect of bupropion on morphine tolerance and dependence in mice.
Topics: Analgesics, Opioid; Animals; Bupropion; Dopamine Uptake Inhibitors; Drug Combinations; Drug Interact | 2004 |
Is antagonism of alpha3beta4 nicotinic receptors a strategy to reduce morphine dependence?
Topics: Acute Disease; Animals; Bupropion; Dextromethorphan; Drug Therapy, Combination; Female; Mecamylamine | 2005 |