Page last updated: 2024-10-17

bupropion and Kidney Failure, Chronic

bupropion has been researched along with Kidney Failure, Chronic in 3 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" Pharmacokinetic analysis was undertaken by non-linear regression using MWPharm."1.32Pharmacokinetics of bupropion and its metabolites in haemodialysis patients who smoke. A single dose study. ( Almond, MK; Dhillon, S; Worrall, SP, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Volpe, DA1
Tobin, GA1
Tavakkoli, F1
Dowling, TC1
Light, PD1
Parker, RJ1
Worrall, SP1
Almond, MK1
Dhillon, S1
DeVane, CL1
Laizure, SC1
Cameron, DF1

Other Studies

3 other studies available for bupropion and Kidney Failure, Chronic

ArticleYear
Effect of uremic serum and uremic toxins on drug metabolism in human microsomes.
    Regulatory toxicology and pharmacology : RTP, 2014, Volume: 68, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Bupropion; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Fe

2014
Pharmacokinetics of bupropion and its metabolites in haemodialysis patients who smoke. A single dose study.
    Nephron. Clinical practice, 2004, Volume: 97, Issue:3

    Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Cohort Studies; Cytochrome

2004
The effect of experimentally-induced renal failure on accumulation of bupropion and its major basic metabolites in plasma and brain of guinea pigs.
    Psychopharmacology, 1986, Volume: 89, Issue:4

    Topics: Animals; Brain Chemistry; Bupropion; Guinea Pigs; Kidney Failure, Chronic; Male; Propiophenones; Ura

1986