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bupropion and Epilepsy, Tonic-Clonic

bupropion has been researched along with Epilepsy, Tonic-Clonic in 14 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Research Excerpts

ExcerptRelevanceReference
"In a placebo-controlled, double-blind study of the unique antidepressant agent bupropion in the treatment of nondepressed subjects with bulimia (bupropion group, N = 55; placebo group, N = 26), we found the drug significantly superior to placebo in reducing episodes of binge eating and purging."9.06Treatment of bulimia with bupropion: a multicenter controlled trial. ( Ascher, J; Cato, A; Ferguson, JM; Horne, RL; Hudson, JI; Lineberry, CG; Pope, HG, 1988)
"Bupropion is a new aid in smoking cessation."8.81[Risk of convulsions due to the use of bupropion as an aid for smoking cessation]. ( Kwan, AL; Lekkerkerker, JF; Meiners, AP; van Grootheest, AC, 2001)
"In a placebo-controlled, double-blind study of the unique antidepressant agent bupropion in the treatment of nondepressed subjects with bulimia (bupropion group, N = 55; placebo group, N = 26), we found the drug significantly superior to placebo in reducing episodes of binge eating and purging."5.06Treatment of bulimia with bupropion: a multicenter controlled trial. ( Ascher, J; Cato, A; Ferguson, JM; Horne, RL; Hudson, JI; Lineberry, CG; Pope, HG, 1988)
"Bupropion is a new aid in smoking cessation."4.81[Risk of convulsions due to the use of bupropion as an aid for smoking cessation]. ( Kwan, AL; Lekkerkerker, JF; Meiners, AP; van Grootheest, AC, 2001)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's9 (64.29)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kolluru, A1
Kumar, P1
Kanwar, M1
Singh, T1
Ickowicz, A1
Bergmann, F1
Bleich, S1
Wischer, S1
Paulus, W1
Jepsen, F1
Matthews, J1
Andrews, FJ1
Rissmiller, DJ1
Campo, T1
Rosoff, DM1
Storrow, AB1
Namerow, LB1
Shrier, M1
Díaz, JE1
Tsarouhas, N1
Tilton, P1
Kwan, AL1
Meiners, AP1
van Grootheest, AC1
Lekkerkerker, JF1
White, RS1
Langford, JR1
Horne, RL1
Ferguson, JM1
Pope, HG1
Hudson, JI1
Lineberry, CG1
Ascher, J1
Cato, A1
Rubin, AL1
Charney, DS1
Price, LH1
Heninger, GR1

Reviews

2 reviews available for bupropion and Epilepsy, Tonic-Clonic

ArticleYear
Bupropion overdose and seizure.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:2

    Topics: Adolescent; Bupropion; Charcoal; Diazepam; Drug Overdose; Electrocardiography; Emergency Service, Ho

1994
[Risk of convulsions due to the use of bupropion as an aid for smoking cessation].
    Nederlands tijdschrift voor geneeskunde, 2001, Feb-10, Volume: 145, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Bupropion; Contraindications; Dopamine Uptake Inhibitors; E

2001

Trials

1 trial available for bupropion and Epilepsy, Tonic-Clonic

ArticleYear
Treatment of bulimia with bupropion: a multicenter controlled trial.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Ambulatory Care; Bulimia; Bupropion; Clinical Trials as Topic; Double-Blind Metho

1988

Other Studies

11 other studies available for bupropion and Epilepsy, Tonic-Clonic

ArticleYear
Heart connection of the mind medication.
    BMJ case reports, 2011, Apr-26, Volume: 2011

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Dizziness; Drug Overdose; Electroca

2011
Bupropion-methylphenidate combination and grand mal seizures.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2002, Volume: 47, Issue:8

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bupropion; Depressive Disorder; Dose-Resp

2002
Seizure and cardiac arrest during bupropion SR treatment.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiopulmonary Resuscitation; Dopamine

2002
Sustained release bupropion overdose: an important cause of prolonged symptoms after an overdose.
    Emergency medicine journal : EMJ, 2003, Volume: 20, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Drug Overdo

2003
Extended-release bupropion induced grand mal seizures.
    The Journal of the American Osteopathic Association, 2007, Volume: 107, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Epilepsy, T

2007
Another case of extended-release bupropion-induced seizure.
    The Journal of the American Osteopathic Association, 2008, Volume: 108, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion; Clonazepam; Delayed-Act

2008
Seizure associated with bupropion and guanfacine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1999, Volume: 38, Issue:1

    Topics: Bupropion; Child; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Guanfacine; Humans

1999
Cardiotoxicity associated with bupropion overdose.
    Annals of emergency medicine, 2000, Volume: 35, Issue:1

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Emergency Treatment;

2000
Seizure after guanfacine plus bupropion: correction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2000, Volume: 39, Issue:11

    Topics: Adolescent; Adrenergic alpha-Agonists; Bupropion; Dopamine Uptake Inhibitors; Epilepsy, Tonic-Clonic

2000
Sustained release bupropion: overdose and treatment.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Drug Overdose; Epi

2002
Rapid improvement of delusional depression following drug-induced seizures: case report.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4

    Topics: Adult; Bupropion; Delusions; Depressive Disorder; Drug Therapy, Combination; Epilepsy, Tonic-Clonic;

1985