bupropion has been researched along with Drug Overdose in 82 studies
Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
Excerpt | Relevance | Reference |
---|---|---|
"Here we describe a wide complex tachycardia after bupropion overdose that was responsive to sodium bicarbonate." | 7.81 | Wide complex tachycardia after bupropion overdose. ( Franco, V, 2015) |
"Delayed seizures have been reported with overdoses of bupropion extended-release (XL)." | 7.75 | Incidence and onset of delayed seizures after overdoses of extended-release bupropion. ( Ekleberry, SE; Kern, P; Klein-Schwartz, W; Kunkel, S; Spiller, H; Starr, P, 2009) |
"Bupropion was the first alternative to nicotine replacement therapy in the pharmacological treatment for smoking cessation." | 7.74 | Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004. ( Beyens, MN; Guy, C; Laporte, S; Mounier, G; Ollagnier, M, 2008) |
"Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 5.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
"She had a seizure and required sedation and intubation." | 5.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
"BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone." | 5.48 | Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018) |
"Bupropion is a monocyclic antidepressant in the aminoketone class, structurally related to amphetamines." | 5.42 | Bupropion Overdose Presenting as Status Epilepticus in an Infant. ( Morgan, R; Patterson, AL; Rivas-Coppola, MS; Wheless, JW, 2015) |
"Bupropion hydrochloride is a monocyclic antidepressant which is used in a slow-release formulation as a smoking cessation aid." | 4.81 | Zyban-- is there a cause for concern? ( Tracey, JA, 2002) |
"Bupropion cardiotoxicity widens QRS complexes by inhibiting cardiac gap junctions." | 4.31 | Sodium bicarbonate treatment for QRS widening in bupropion overdoses. ( Goldfine, C; Johnson, L; Simpson, M, 2023) |
"Here we describe a wide complex tachycardia after bupropion overdose that was responsive to sodium bicarbonate." | 3.81 | Wide complex tachycardia after bupropion overdose. ( Franco, V, 2015) |
"Bupropion overdose commonly causes generalized seizures and central nervous system depression." | 3.79 | Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. ( Al-Abri, SA; Benowitz, NL; Hayashi, S; Olson, KR; Orengo, JP; Thoren, KL, 2013) |
"Delayed seizures have been reported with overdoses of bupropion extended-release (XL)." | 3.75 | Incidence and onset of delayed seizures after overdoses of extended-release bupropion. ( Ekleberry, SE; Kern, P; Klein-Schwartz, W; Kunkel, S; Spiller, H; Starr, P, 2009) |
"Bupropion was the first alternative to nicotine replacement therapy in the pharmacological treatment for smoking cessation." | 3.74 | Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004. ( Beyens, MN; Guy, C; Laporte, S; Mounier, G; Ollagnier, M, 2008) |
"Bupropion overdose mainly is characterized by tachycardia, agitation, and seizures." | 3.73 | Intraventricular conduction delay after bupropion overdose. ( Curry, SC; Holubek, W; Kashani, JS; LoVecchio, F, 2005) |
"Bupropion (Zyban) has recently been launched in the UK as an aid to smoking cessation." | 3.71 | Bupropion overdose: a potential problem with the new 'miracle' anti-smoking drug. ( Bhattacharjee, C; Gillespie, M; Smith, M; Todd, F, 2001) |
"Bupropion is a unique monocyclic antidepressant that has been known to cause seizures in high therapeutic doses and in acute overdoses." | 3.69 | Fatal bupropion overdose. ( Gualtieri, J; Harris, CR; Stark, G, 1997) |
"Clinical features associated with seizure were QTc >500 (OR = 3." | 2.72 | Factors associated with seizure development after bupropion overdose: a review of the toxicology investigators consortium. ( Hendrickson, RG; Lin, AL; Murray, BP; Prather, CT; Rianprakaisang, TN, 2021) |
"Preferred drugs for treating depression in epilepsy are serotonin reuptake inhibitors." | 2.49 | [Antidepressants in epilepsy]. ( Castaño-Monsalve, B, 2013) |
"Bupropion is a relatively new monocyclic antidepressant whose mechanism of action remains unknown." | 2.41 | Bupropion overdose in an adolescent. ( Ayers, S; Tobias, JD, 2001) |
"Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD." | 1.72 | Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022) |
"Bupropion is an antidepressant with unique mechanisms of action leading to a narrow therapeutic window." | 1.72 | Disposition, outcomes, and lengths of stay due to bupropion overdose at a tertiary care center with a medical toxicology service. ( McCabe, DJ; Radke, JB; Wilson, BZ, 2022) |
"She had a seizure and required sedation and intubation." | 1.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
"Bupropion overdose is a commonly encountered presentation in the emergency department (ED)." | 1.56 | Bupropion Overdose Complicated by Cardiogenic Shock Requiring Vasopressor Support and Lipid Emulsion Therapy. ( Fung, C; Herrman, NWC; Kalisieski, MJ, 2020) |
"Bupropion is a commonly used antidepressant, and overdose can lead to both neurologic and cardiovascular toxicity, including agitation, seizure, tachycardia, QT and QRS prolongation, and rhythm disturbances." | 1.51 | Pediatric Toxidrome Simulation Curriculum: Bupropion Overdose. ( Burns, R; Hartford, E; Keilman, A; Reid, J; Stone, K; Thomas, A; Uspal, N, 2019) |
" Case Discussion: "Ghost tablets," the insoluble remnant of some extended-release dosage forms, have been previously reported to appear in patients' stool in the course of therapeutic dosing." | 1.51 | "Ghost tablet" husks excreted in feces in large bupropion XL overdose. ( Nanagas, K; Overberg, A; Purpura, A, 2019) |
"Bupropion exposure was significantly associated with death (0." | 1.51 | Toxicity of Bupropion Overdose Compared With Selective Serotonin Reuptake Inhibitors. ( Froberg, B; Morton, S; Overberg, A; Wagner, E, 2019) |
"BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone." | 1.48 | Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018) |
"Its primary toxic effects include seizure, sinus tachycardia, hypertension, and agitation; however, at higher amounts of ingestion, paradoxical cardiac effects are seen." | 1.43 | Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues. ( Jimenez, XF; Kolawole, T; Zhu, Y, 2016) |
"The FDA addressed interchangeability problems with generic modified-release alternatives of bupropion and methylphenidate including lack of bioequivalence, reduced efficacy, and increased incidence of adverse events." | 1.43 | Interchangeability, Safety and Efficacy of Modified-Release Drug Formulations in the USA: The Case of Opioid and Other Nervous System Drugs. ( Hansen, R; Rodriguez-Monguio, R; Seoane-Vazquez, E, 2016) |
"Bupropion is a monocyclic antidepressant in the aminoketone class, structurally related to amphetamines." | 1.42 | Bupropion Overdose Presenting as Status Epilepticus in an Infant. ( Morgan, R; Patterson, AL; Rivas-Coppola, MS; Wheless, JW, 2015) |
"Bupropion is a relatively new and popular medication for depression, with seizures as its major side effect." | 1.40 | Charcoal hemoperfusion in bupropion overdose. ( Akdemir, HU; Calışkan, F; Duran, L; Güngörer, B; Katı, C; Ocak, M, 2014) |
"Bupropion is an I(Kr) blocker." | 1.38 | QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. ( Caillier, B; Castonguay, A; Daleau, P; De Koninck, Y; Drolet, B; Hreiche, R; Ménard-Desrosiers, V; Patoine, D; Pilote, S; Simard, C; Turgeon, J; Vigneault, P, 2012) |
"Bupropion is an antidepressant, which in Denmark is only used as an aid for smoking cessation." | 1.35 | [Acute psychosis following bupropion overdosage]. ( Braendholt, V; Hansen, MB; Rasmussen, KB, 2008) |
" Other prominent adverse effects were agitation (39 patients [8." | 1.33 | Adverse effects associated with extra doses of bupropion. ( Shepherd, G, 2005) |
"Bupropion is an antidepressant that is structurally related to amphetamines and enhances dopamine neurotransmission through inhibiting neuronal dopamine re-uptake." | 1.33 | Acute psychosis following sustained release bupropion overdose. ( Chang, CC; Shiah, IS; Wang, TS; Yeh, CB, 2005) |
"Seizures were dose-dependent, with those having seizures ingesting a significantly higher median dose (P = 0." | 1.32 | Bupropion poisoning: a case series. ( Balit, CR; Isbister, GK; Lynch, CN, 2003) |
" They have apparently safe cardiac safety profiles in both therapeutic and supra-therapeutic doses." | 1.32 | Cardiotoxicity associated with intentional ziprasidone and bupropion overdose. ( Biswas, AK; Mayes, KL; Morris-Kukoski, CL; Zabrocki, LA, 2003) |
"However, seizures may occur beyond this time frame, particularly if persistent tachycardia, agitation, or hallucinations are noted." | 1.32 | Intentional bupropion overdoses. ( Keyes, DC; Shepherd, G; Velez, LI, 2004) |
" They have apparently safe cardiac safety profiles in both therapeutic and supratherapeutic doses, but recently the Federal Drug Administration has issued a caution regarding ziprasidone use in combination with other drugs that are known to prolong the QTc interval." | 1.32 | Cardiotoxicity associated with intentional ziprasidone and bupropion overdose. ( Biswas, AK; Mayes, KL; Morris-Kukoski, CL; Zabrocki, LA, 2003) |
"Bupropion is an antidepressant and smoking cessation aid." | 1.31 | Bupropion exposures: clinical manifestations and medical outcome. ( Belson, MG; Kelley, TR, 2002) |
" The potential toxic effects should be considered when prescribing it as a smoking cessation aid." | 1.31 | Bupropion (Zyban) toxicity. ( Ali, I; Casey, PB; Cassidy, N; Tracey, JA, 2002) |
"Seizure is the primary adverse reaction associated with bupropion overdoses." | 1.30 | ECG conduction delays associated with massive bupropion overdose. ( Paris, PA; Saucier, JR, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (6.10) | 18.2507 |
2000's | 28 (34.15) | 29.6817 |
2010's | 34 (41.46) | 24.3611 |
2020's | 15 (18.29) | 2.80 |
Authors | Studies |
---|---|
McCabe, DJ | 1 |
Radke, JB | 1 |
Wilson, BZ | 1 |
Robinson, S | 1 |
Simpson, M | 1 |
Johnson, L | 2 |
Goldfine, C | 1 |
Lothet, E | 1 |
Fredrickson, C | 1 |
Nguyen, KL | 1 |
Bertels, K | 1 |
Mullins, ME | 2 |
Herrman, NWC | 1 |
Kalisieski, MJ | 1 |
Fung, C | 1 |
Hartford, E | 1 |
Thomas, A | 1 |
Keilman, A | 1 |
Uspal, N | 1 |
Stone, K | 1 |
Reid, J | 1 |
Burns, R | 1 |
Offerman, S | 1 |
Gosen, J | 1 |
Thomas, SH | 1 |
Padilla-Jones, A | 1 |
Ruha, AM | 1 |
Levine, M | 1 |
Seger, DL | 1 |
Sidlak, AM | 2 |
Koivisto, KO | 1 |
Marino, RT | 2 |
Abesamis, MG | 2 |
Taub, ES | 1 |
Hoffman, RS | 1 |
Howland, MA | 1 |
Su, MK | 1 |
Prakash, S | 1 |
Lee, SH | 1 |
Sohn, JT | 1 |
Murray, BP | 2 |
Carpenter, JE | 1 |
Sayers, J | 1 |
Yeh, M | 1 |
Beau, J | 1 |
Kiernan, EA | 1 |
Wolf, MJ | 1 |
Bolton, TA | 1 |
Kazzi, Z | 1 |
Rianprakaisang, TN | 1 |
Prather, CT | 1 |
Lin, AL | 1 |
Hendrickson, RG | 1 |
Sathe, AR | 1 |
Thiemann, A | 1 |
Toulouie, S | 1 |
Durant, E | 1 |
Schmit, G | 1 |
De Boosere, E | 1 |
Vanhaebost, J | 1 |
Capron, A | 1 |
Xiang, XM | 1 |
Phillips, DJ | 1 |
Little, K | 1 |
Lin, CM | 1 |
Reynolds, PM | 1 |
Overberg, A | 2 |
Purpura, A | 1 |
Nanagas, K | 1 |
Cartier R, L | 1 |
Romero O, C | 1 |
Pérez P, G | 1 |
French, S | 1 |
Wray, C | 1 |
Morton, S | 1 |
Wagner, E | 1 |
Froberg, B | 1 |
Wilson, B | 1 |
Paul, P | 1 |
Mehta, S | 1 |
Coffey, BJ | 1 |
Hilliard, WT | 1 |
Barloon, L | 1 |
Farley, P | 1 |
Penn, JV | 1 |
Koranek, A | 1 |
Castaño-Monsalve, B | 1 |
Bucklin, MH | 1 |
Gorodetsky, RM | 1 |
Wiegand, TJ | 1 |
Al-Abri, SA | 1 |
Orengo, JP | 1 |
Hayashi, S | 1 |
Thoren, KL | 1 |
Benowitz, NL | 1 |
Olson, KR | 1 |
Akdemir, HU | 1 |
Calışkan, F | 1 |
Duran, L | 1 |
Katı, C | 1 |
Güngörer, B | 1 |
Ocak, M | 1 |
Stall, N | 1 |
Godwin, J | 1 |
Juurlink, D | 1 |
Fettiplace, MR | 1 |
Akpa, BS | 1 |
Rubinstein, I | 1 |
Weinberg, G | 1 |
Weerdenburg, K | 1 |
Finkelstein, Y | 1 |
Rivas-Coppola, MS | 1 |
Patterson, AL | 1 |
Morgan, R | 1 |
Wheless, JW | 1 |
Franco, V | 1 |
Seoane-Vazquez, E | 1 |
Rodriguez-Monguio, R | 1 |
Hansen, R | 1 |
Heise, CW | 1 |
Skolnik, AB | 1 |
Raschke, RA | 1 |
Owen-Reece, H | 1 |
Graeme, KA | 1 |
Fulton, LV | 1 |
Fabich, RA | 1 |
Bhatta, J | 1 |
Fletcher, B | 1 |
Leininger, K | 1 |
Lienesch, K | 1 |
Rodriguez, TA | 1 |
Coyner, JL | 1 |
Johnson, AD | 1 |
O'Sullivan, J | 1 |
Bolen, RD | 1 |
Campbell, Z | 1 |
Bonilha, L | 1 |
Edwards, JC | 1 |
Farias-Moeller, R | 1 |
Carpenter, JL | 1 |
Zhu, Y | 1 |
Kolawole, T | 1 |
Jimenez, XF | 1 |
Spiller, HA | 3 |
Schaeffer, SE | 1 |
Beyens, MN | 1 |
Guy, C | 1 |
Mounier, G | 1 |
Laporte, S | 1 |
Ollagnier, M | 1 |
Hansen, MB | 1 |
Rasmussen, KB | 1 |
Braendholt, V | 1 |
Bottei, E | 1 |
Kalin, L | 1 |
Garg, U | 1 |
Frazee, C | 1 |
Turner, JW | 1 |
Starr, P | 1 |
Klein-Schwartz, W | 1 |
Spiller, H | 1 |
Kern, P | 1 |
Ekleberry, SE | 1 |
Kunkel, S | 1 |
Donnelly, K | 1 |
Walkowiak, HB | 1 |
Donnelly, C | 1 |
Jenkinson, E | 1 |
Rizkalla, J | 1 |
Langford, N | 1 |
Boora, K | 1 |
Cummings, MR | 1 |
Marshall, DR | 1 |
Shenoi, AN | 1 |
Gertz, SJ | 1 |
Mikkilineni, S | 1 |
Kalyanaraman, M | 1 |
Caillier, B | 1 |
Pilote, S | 1 |
Castonguay, A | 1 |
Patoine, D | 1 |
Ménard-Desrosiers, V | 1 |
Vigneault, P | 1 |
Hreiche, R | 1 |
Turgeon, J | 1 |
Daleau, P | 1 |
De Koninck, Y | 1 |
Simard, C | 1 |
Drolet, B | 1 |
Skjei, KL | 1 |
Kessler, SK | 1 |
Abend, NS | 1 |
Chao, CT | 1 |
Wu, VC | 1 |
Wang, WJ | 1 |
Lung, D | 1 |
Yeh, K | 1 |
Kiang, C | 1 |
Kolluru, A | 1 |
Kumar, P | 1 |
Kanwar, M | 1 |
Singh, T | 1 |
Lin, YH | 1 |
Huang, E | 1 |
Chien, YL | 1 |
Druteika, D | 1 |
Zed, PJ | 1 |
Belson, MG | 1 |
Kelley, TR | 1 |
Balit, CR | 1 |
Lynch, CN | 1 |
Isbister, GK | 1 |
Biswas, AK | 2 |
Zabrocki, LA | 2 |
Mayes, KL | 2 |
Morris-Kukoski, CL | 2 |
Tracey, JA | 2 |
Jepsen, F | 1 |
Matthews, J | 1 |
Andrews, FJ | 1 |
Jaffe, R | 1 |
Leavitt, R | 1 |
Wind, T | 1 |
Shepherd, G | 2 |
Velez, LI | 1 |
Keyes, DC | 1 |
Wang, TS | 1 |
Shiah, IS | 1 |
Yeh, CB | 1 |
Chang, CC | 1 |
Curry, SC | 1 |
Kashani, JS | 1 |
LoVecchio, F | 1 |
Holubek, W | 1 |
Suma, R | 1 |
Kosanam, H | 1 |
Sai Prakash, PK | 1 |
Dattilo, PB | 1 |
Nordin, C | 1 |
Mercerolle, M | 1 |
Denooz, R | 1 |
Lachâtre, G | 1 |
Charlier, C | 1 |
Storrow, AB | 1 |
Ramoska, EA | 1 |
Krenzelok, EP | 1 |
Sheen, SR | 1 |
Borys, DJ | 1 |
Villalobos, D | 1 |
Muir, S | 1 |
Jones-Easom, L | 1 |
Gittelman, DK | 1 |
Kirby, MG | 1 |
Harris, CR | 1 |
Gualtieri, J | 1 |
Stark, G | 1 |
Paris, PA | 1 |
Saucier, JR | 1 |
Shrier, M | 1 |
Díaz, JE | 1 |
Tsarouhas, N | 1 |
Ayers, S | 1 |
Tobias, JD | 1 |
Bhattacharjee, C | 1 |
Smith, M | 1 |
Todd, F | 1 |
Gillespie, M | 1 |
Mainie, I | 1 |
McGurk, C | 1 |
McClintock, G | 1 |
Robinson, J | 1 |
Cassidy, N | 1 |
Casey, PB | 1 |
Ali, I | 1 |
Paoloni, R | 1 |
Szekely, I | 1 |
White, RS | 1 |
Langford, JR | 1 |
7 reviews available for bupropion and Drug Overdose
Article | Year |
---|---|
Factors associated with seizure development after bupropion overdose: a review of the toxicology investigators consortium.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; | 2021 |
Bupropion diversion and misuse in the correctional facility.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Mental Disorders; Prison | 2013 |
[Antidepressants in epilepsy].
Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bupropion; Clinical Trials | 2013 |
Cardiotoxicity following bupropion overdose.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Electrocardio | 2002 |
Zyban-- is there a cause for concern?
Topics: Animals; Antidepressive Agents, Second-Generation; Area Under Curve; Bupropion; Drug Overdose; Half- | 2002 |
Bupropion overdose and seizure.
Topics: Adolescent; Bupropion; Charcoal; Diazepam; Drug Overdose; Electrocardiography; Emergency Service, Ho | 1994 |
Bupropion overdose in an adolescent.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bupropion; Dopamine Uptake Inhibitors; Dr | 2001 |
75 other studies available for bupropion and Drug Overdose
Article | Year |
---|---|
Disposition, outcomes, and lengths of stay due to bupropion overdose at a tertiary care center with a medical toxicology service.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Seizures; Tertiary Care | 2022 |
Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Drug Overdose; Fema | 2022 |
Sodium bicarbonate treatment for QRS widening in bupropion overdoses.
Topics: Adult; Bicarbonates; Bupropion; Cardiotoxicity; Drug Overdose; Electrocardiography; Female; Humans; | 2023 |
Intentional overdose of a novel dextromethorphan-bupropion combination antidepressant.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Bupropion; Dextromethorphan; Drug O | 2023 |
Bupropion Overdose Complicated by Cardiogenic Shock Requiring Vasopressor Support and Lipid Emulsion Therapy.
Topics: Bupropion; Drug Overdose; Fat Emulsions, Intravenous; Female; Humans; Shock, Cardiogenic; Vasoconstr | 2020 |
Pediatric Toxidrome Simulation Curriculum: Bupropion Overdose.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiopulmonary Resuscitation; Clin | 2019 |
Bupropion associated seizures following acute overdose: who develops late seizures.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Dose-Response Relationship, | 2020 |
Antidotal use of lipid emulsion - the pendulum swings.
Topics: Animals; Antidotes; Bupropion; Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; | 2020 |
Serotonin toxicity from isolated bupropion overdoses.
Topics: Adolescent; Adult; Bupropion; Drug Overdose; Female; Humans; Male; Middle Aged; Retrospective Studie | 2020 |
Response to Comment on serotonin toxicity from isolated bupropion overdoses.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Serotonin | 2021 |
Comment on Serotonin toxicity from isolated bupropion overdoses.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Serotonin | 2020 |
Comment on Serotonin toxicity from isolated bupropion overdoses.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Serotonin | 2020 |
Lipid Emulsion Treatment of Cardiogenic Shock Induced by Toxic Dose of Bupropion.
Topics: Bupropion; Drug Overdose; Fat Emulsions, Intravenous; Humans; Lipids; Shock, Cardiogenic | 2020 |
Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine.
Topics: Adolescent; Adult; Bupropion; Cyproheptadine; Drug Overdose; Female; Humans; Male; Seizures; Seroton | 2021 |
A 19-Year-Old Woman with a History of Depression and Fatal Cardiorespiratory Failure Following an Overdose of Prescribed Bupropion.
Topics: Adolescent; Adult; Bupropion; Depression; Drug Overdose; Female; Humans; Seizures; Shock, Cardiogeni | 2021 |
Bupropion Overdose Resulted in a Pharmacobezoar in a Fatal Bupropion (Wellbutrin
Topics: Adult; Antidepressive Agents, Second-Generation; Bezoars; Bile; Bupropion; Delayed-Action Preparatio | 2017 |
Nonepileptic Myoclonus Following Bupropion Overdose.
Topics: Adolescent; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion; Depressive Disorde | 2018 |
Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose.
Topics: Benzodiazepines; Bupropion; Cyproheptadine; Dopamine Uptake Inhibitors; Drug Overdose; Fluoxetine; H | 2018 |
"Ghost tablet" husks excreted in feces in large bupropion XL overdose.
Topics: Bupropion; Delayed-Action Preparations; Drug Overdose; Feces; Humans; Male; Tablets; Young Adult | 2019 |
[Sustained upgaze in a patient who ingested high doses of bupropion. Report of one case].
Topics: Aged; Antidepressive Agents, Second-Generation; Bupropion; Coma; Drug Overdose; Fatal Outcome; Femal | 2018 |
Serotonin Syndrome and Hippocampal Infarction.
Topics: Adolescent; Brain Infarction; Bupropion; Drug Overdose; Fever; Hallucinations; Hippocampus; Humans; | 2019 |
Toxicity of Bupropion Overdose Compared With Selective Serotonin Reuptake Inhibitors.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Child; Drug Overdose; Female; Human | 2019 |
Hypokalemia secondary to bupropion sustained release overdose.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Drug O | 2013 |
Prolonged lipemia and pancreatitis due to extended infusion of lipid emulsion in bupropion overdose.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Dopamine Uptake Inhibitors; Drug Ov | 2013 |
Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxins; Drug Overdose; Electrocard | 2013 |
Charcoal hemoperfusion in bupropion overdose.
Topics: Antidepressive Agents, Second-Generation; Antidotes; Bupropion; Charcoal; Depressive Disorder; Drug | 2014 |
Bupropion abuse and overdose.
Topics: Antidepressive Agents; Bupropion; Drug Overdose; Humans; Seizures; Substance-Related Disorders; Toba | 2014 |
Confusion About Infusion: Rational Volume Limits for Intravenous Lipid Emulsion During Treatment of Oral Overdoses.
Topics: Bupropion; Drug Overdose; Fat Emulsions, Intravenous; Humans; Lamotrigine; Triazines | 2015 |
A 12-year-old girl with seizures after intentional drug overdose. Bupropion overdose.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Child; Diagnosis, Differential; Drug Overdose; | 2015 |
Bupropion Overdose Presenting as Status Epilepticus in an Infant.
Topics: Antidepressive Agents, Second-Generation; Brain; Bupropion; Diagnosis, Differential; Drug Overdose; | 2015 |
Wide complex tachycardia after bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Electrocardiography; Emer | 2015 |
Interchangeability, Safety and Efficacy of Modified-Release Drug Formulations in the USA: The Case of Opioid and Other Nervous System Drugs.
Topics: Analgesics, Opioid; Antidepressive Agents, Second-Generation; Bupropion; Centers for Medicare and Me | 2016 |
Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrane Oxygenation.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Arizona; Bupropion; Combined Modality Therapy; | 2016 |
Comparison of Resuscitative Protocols for Bupropion Overdose Using Lipid Emulsion in a Swine Model.
Topics: Animals; Bupropion; Cardiopulmonary Resuscitation; Drug Overdose; Epinephrine; Fat Emulsions, Intrav | 2016 |
Alpha coma related to intentional bupropion overdose.
Topics: Antidepressive Agents, Second-Generation; Brain; Bupropion; Coma; Depressive Disorder; Drug Overdose | 2016 |
Coma with Absent Brainstem Reflexes and Burst Suppression after Bupropion Overdose in a Child.
Topics: Adolescent; Brain Edema; Brain Stem; Bupropion; Coma; Drug Overdose; Fatal Outcome; Female; Humans; | 2017 |
Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Electrocardiography; Fema | 2016 |
Multiple seizures after bupropion overdose in a small child.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Child; Drug Overdose; Emergency Service, Hospit | 2008 |
Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004.
Topics: Adolescent; Adult; Aged; Angioedema; Antidepressive Agents, Second-Generation; Bupropion; Cerebrovas | 2008 |
[Acute psychosis following bupropion overdosage].
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Hallucinations; Huma | 2008 |
Fatal bupropion overdose with post mortem blood concentrations.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; | 2008 |
A fatal case involving extremely high levels of ethylene glycol without elevation of its metabolites or crystalluria.
Topics: Antidepressive Agents; Bupropion; Drug Overdose; Ethylene Glycol; Forensic Toxicology; Glycolates; G | 2009 |
Incidence and onset of delayed seizures after overdoses of extended-release bupropion.
Topics: Adolescent; Adult; Aged; Bupropion; Chi-Square Distribution; Child; Child, Preschool; Dopamine Uptak | 2009 |
Bupropion toxicokinetic: a case report.
Topics: Adult; Antidepressive Agents; Bupropion; Delayed-Action Preparations; Drug Overdose; Humans; Male | 2010 |
Generalized seizure in three adolescents with bupropion overdose.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Humans; Male | 2010 |
Refractory hypotension from massive bupropion overdose successfully treated with extracorporeal membrane oxygenation.
Topics: Antidepressive Agents, Second-Generation; Blood Pressure; Bupropion; Drug Overdose; Extracorporeal M | 2011 |
QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.
Topics: Animals; Antidepressive Agents, Second-Generation; Bupropion; Cell Communication; Cell Line; CHO Cel | 2012 |
Stimulus-induced rhythmic, periodic, or ictal discharges in a 13-year-old girl after an overdose and respiratory arrest.
Topics: Adolescent; Baclofen; Bupropion; Drug Overdose; Female; Heart Arrest; Humans; Periodicity; Seizures | 2011 |
Charcoal hemoperfusion for bupropion overdose with ventricular tachycardia and status epilepticus.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Charcoal; Drug Overdose; Electrocar | 2012 |
Delayed, fatal cardiotoxicity associated with bupropion and citalopram overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxins; Citalopram; Delayed-Action | 2012 |
Heart connection of the mind medication.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Dizziness; Drug Overdose; Electroca | 2011 |
Bilateral pallidal necrosis and cardiac toxicity in a patient with venlafaxine and bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Drug Overdose; Female; Gl | 2012 |
Bupropion exposures: clinical manifestations and medical outcome.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion | 2002 |
Bupropion poisoning: a case series.
Topics: Accidents, Home; Adult; Australia; Bupropion; Child, Preschool; Dopamine Uptake Inhibitors; Drug Ove | 2003 |
Cardiotoxicity associated with intentional ziprasidone and bupropion overdose.
Topics: Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bupro | 2003 |
Cardiotoxicity associated with intentional ziprasidone and bupropion overdose.
Topics: Adolescent; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; | 2003 |
Sustained release bupropion overdose: an important cause of prolonged symptoms after an overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Drug Overdo | 2003 |
QTc prolongation in multiple drug overdose.
Topics: Adult; Bupropion; Drug Overdose; Fluoxetine; Humans; Long QT Syndrome; Male; Piperazines; Psychotic | 2004 |
Intentional bupropion overdoses.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Child; Drug Overdose; Female | 2004 |
Acute psychosis following sustained release bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidotes; Bupropion; Charcoal; Delayed-Action Prep | 2005 |
Intraventricular conduction delay after bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Electrocardiography; Fema | 2005 |
Adverse effects associated with extra doses of bupropion.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Bupropion; Dru | 2005 |
Stability study of bupropion and olanzapine in formaldehyde solutions.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bupropion; Chemistr | 2006 |
Prolonged QT associated with an overdose of trazodone.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Depression; Drug Overdose; Electrocardio | 2007 |
A fatal case of bupropion (Zyban) overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cause of Death; Chromatography, High Pre | 2008 |
Bupropion overdose: a 3-year multi-center retrospective analysis.
Topics: Adolescent; Adult; Aged; Benzodiazepines; Bupropion; Child; Child, Preschool; Drug Overdose; Female; | 1994 |
A seizure following bupropion overdose.
Topics: Adult; Bupropion; Depressive Disorder; Drug Overdose; Female; Humans; Seizures | 1993 |
Fatal bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Dopamine; Drug Overdose; Fatal Outcome; | 1997 |
ECG conduction delays associated with massive bupropion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Bupropion; Delirium; Drug Ove | 1998 |
Cardiotoxicity associated with bupropion overdose.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Emergency Treatment; | 2000 |
Bupropion overdose: a potential problem with the new 'miracle' anti-smoking drug.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Dopamine; Drug Overdose; Epinephrin | 2001 |
Seizures after buproprion overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Follow-Up Studies | 2001 |
Bupropion (Zyban) toxicity.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Humans; Ireland; | 2002 |
Sustained-release bupropion overdose: a new entity for Australian emergency departments.
Topics: Adult; Australia; Bupropion; Combined Modality Therapy; Delayed-Action Preparations; Drug Overdose; | 2002 |
Sustained release bupropion: overdose and treatment.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Drug Overdose; Epi | 2002 |