Page last updated: 2024-10-17

bupropion and Disruptive, Impulse Control, and Conduct Disorders

bupropion has been researched along with Disruptive, Impulse Control, and Conduct Disorders in 4 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Disruptive, Impulse Control, and Conduct Disorders: Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.

Research Excerpts

ExcerptRelevanceReference
"Pathological gambling is substantially more prevalent among cocaine-dependent outpatients than in the general population."2.69Pathological gambling among cocaine-dependent outpatients. ( Carriero, NJ; Gorelick, DA; Hall, GW; Montoya, ID; Preston, KL; Takushi, RY, 2000)
"Pathological gambling is frequently comorbid with bipolar spectrum disorders, substance abuse/dependence, and attention-deficit/hyperactivity disorder (ADHD), and comorbidity may influence treatment response in pathological gambling."2.43Pharmacological treatments of pathological gambling. ( Baker, B; Baldini-Rossi, N; Hollander, E; Pallanti, S; Sood, E, 2005)
"Bupropion-treated smokers had smaller cigarette cue-induced increases in craving scores on the Urge to Smoke (UTS) Scale and less activation of perigenual/ventral ACC metabolism from the neutral to the cigarette cue scan than untreated smokers."1.32Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study. ( Brody, AL; Jarvik, ME; Lee, G; London, ED; Mandelkern, MA; Sadeghi, M; Saxena, S; Smith, E, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tidey, JW1
Rohsenow, DJ1
Brody, AL1
Mandelkern, MA1
Lee, G1
Smith, E1
Sadeghi, M1
Saxena, S1
Jarvik, ME1
London, ED1
Hollander, E1
Sood, E1
Pallanti, S1
Baldini-Rossi, N1
Baker, B1
Hall, GW1
Carriero, NJ1
Takushi, RY1
Montoya, ID1
Preston, KL1
Gorelick, DA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
The STOP Study: Real World Effectiveness of Zyban Treatment in a Clinical Population[NCT01015170]Phase 4454 participants (Actual)Interventional2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

7-day Point Prevalence of Smoking Abstinence

"Number of participants who report Not Smoking (not even a puff) in past 7 days when asked at week 8" (NCT01015170)
Timeframe: End of Treatment (8 weeks after Zyban start date)

Interventionparticipants (Number)
Still smokingQuit smoking
Nicotine Replacement & Behavioural Support109106

Reviews

1 review available for bupropion and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Pharmacological treatments of pathological gambling.
    Journal of gambling studies, 2005,Spring, Volume: 21, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Behavior, Addictive; Bupropion; Comorbidity; Disruptive, I

2005

Trials

1 trial available for bupropion and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Pathological gambling among cocaine-dependent outpatients.
    The American journal of psychiatry, 2000, Volume: 157, Issue:7

    Topics: Adolescent; Adult; Age of Onset; Ambulatory Care; Bromocriptine; Bupropion; Carbamazepine; Cocaine-R

2000

Other Studies

2 other studies available for bupropion and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Intention to quit moderates the effect of bupropion on smoking urge.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2009, Volume: 11, Issue:3

    Topics: Adult; Bupropion; Disruptive, Impulse Control, and Conduct Disorders; Female; Humans; Intention; Mal

2009
Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study.
    Psychiatry research, 2004, Apr-30, Volume: 130, Issue:3

    Topics: Adult; Bupropion; Cues; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Uptake Inhibito

2004
Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study.
    Psychiatry research, 2004, Apr-30, Volume: 130, Issue:3

    Topics: Adult; Bupropion; Cues; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Uptake Inhibito

2004
Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study.
    Psychiatry research, 2004, Apr-30, Volume: 130, Issue:3

    Topics: Adult; Bupropion; Cues; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Uptake Inhibito

2004
Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study.
    Psychiatry research, 2004, Apr-30, Volume: 130, Issue:3

    Topics: Adult; Bupropion; Cues; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Uptake Inhibito

2004