Page last updated: 2024-10-17

bupropion and Disorders of Excessive Somnolence

bupropion has been researched along with Disorders of Excessive Somnolence in 5 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)

Research Excerpts

ExcerptRelevanceReference
"Fatigue and sleepiness (hypersomnia) are symptoms that are highly prevalent in patients with major depressive disorder (MDD)."2.43Symptoms of fatigue and sleepiness in major depressive disorder. ( Baldwin, DS; Papakostas, GI, 2006)
"There was a greater improvement in hypersomnia scores among bupropion-treated than SSRI-treated (p < ."2.43Resolution of sleepiness and fatigue in major depressive disorder: A comparison of bupropion and the selective serotonin reuptake inhibitors. ( Fava, M; Hallett, LA; Krishen, A; Nutt, DJ; Papakostas, GI; Tucker, VL, 2006)
"Insomnia and daytime sleepiness are often associated with depression."2.42Daytime sleepiness and insomnia as correlates of depression. ( Fava, M, 2004)
"Fatigue is a common symptom in individuals with multiple sclerosis (MS)."1.39Reward responsiveness and fatigue in multiple sclerosis. ( Capello, E; Krueger, F; Mancardi, G; Pardini, M; Uccelli, A, 2013)
"Tranylcypromine was effective in the treatment of 14 patients meeting both the National Institute of Mental Health and DSM-III-R criteria for winter depression."1.28Pharmacological responsiveness of winter depression. ( Del Medico, VJ; Dilsaver, SC; Jaeckle, S; Quadri, A, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pardini, M1
Capello, E1
Krueger, F1
Mancardi, G1
Uccelli, A1
Fava, M2
Baldwin, DS1
Papakostas, GI2
Nutt, DJ1
Hallett, LA1
Tucker, VL1
Krishen, A1
Dilsaver, SC1
Del Medico, VJ1
Quadri, A1
Jaeckle, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Music to Improve Sleep Quality in Adults With Depression and Insomnia: a Randomized Controlled Trial Using Mixed Methods[NCT03676491]112 participants (Actual)Interventional2018-05-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for bupropion and Disorders of Excessive Somnolence

ArticleYear
Daytime sleepiness and insomnia as correlates of depression.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 16

    Topics: Antidepressive Agents; Benzhydryl Compounds; Bupropion; Comorbidity; Depressive Disorder; Disorders

2004
Symptoms of fatigue and sleepiness in major depressive disorder.
    The Journal of clinical psychiatry, 2006, Volume: 67 Suppl 6

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Benzhydryl Compounds; Bupropion; Ce

2006
Resolution of sleepiness and fatigue in major depressive disorder: A comparison of bupropion and the selective serotonin reuptake inhibitors.
    Biological psychiatry, 2006, Dec-15, Volume: 60, Issue:12

    Topics: Adult; Aged; Bupropion; Depressive Disorder, Major; Disorders of Excessive Somnolence; Dopamine Upta

2006

Other Studies

2 other studies available for bupropion and Disorders of Excessive Somnolence

ArticleYear
Reward responsiveness and fatigue in multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2013, Volume: 19, Issue:2

    Topics: Adult; Anxiety; Attention; Bupropion; Citalopram; Cognition; Depression; Disability Evaluation; Diso

2013
Pharmacological responsiveness of winter depression.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:3

    Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder; Desipramine; Disorders of Excessive So

1990