Page last updated: 2024-10-17

bupropion and Arrhythmias, Cardiac

bupropion has been researched along with Arrhythmias, Cardiac in 5 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"Increasing age, seizures, QRS widening, and QTc prolongation were associated with adverse cardiovascular events in bupropion exposures."4.31Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures. ( Burns, MM; Feng, C; Monuteaux, M; Simpson, M; Troger, A; Whitledge, JD, 2023)
"Severe orthostatic hypotension is more likely to develop in depressed patients with left ventricular impairment and/or in patients taking other drugs like diuretics or vasodilators."2.38Review of the cardiovascular effects of heterocyclic antidepressants. ( Glassman, AH; Preud'homme, XA, 1993)
"Seizure is the primary adverse reaction associated with bupropion overdoses."1.30ECG conduction delays associated with massive bupropion overdose. ( Paris, PA; Saucier, JR, 1998)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Simpson, M1
Troger, A1
Feng, C1
Whitledge, JD1
Monuteaux, M1
Burns, MM1
Leventhal, K1
Byatt, N1
Lundquist, R1
Roose, SP1
Glassman, AH2
Preud'homme, XA1
Paris, PA1
Saucier, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000526]Phase 30 participants Interventional1986-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for bupropion and Arrhythmias, Cardiac

ArticleYear
Antidepressant choice in the patient with cardiac disease: lessons from the Cardiac Arrhythmia Suppression Trial (CAST) studies.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl A

    Topics: Age Factors; Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Antidepressive Agents, Tricycli

1994
Review of the cardiovascular effects of heterocyclic antidepressants.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bupropion;

1993

Other Studies

3 other studies available for bupropion and Arrhythmias, Cardiac

ArticleYear
Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:7

    Topics: Adult; Arrhythmias, Cardiac; Bupropion; Female; Humans; Long QT Syndrome; Male; Retrospective Studie

2023
Fetal cardiac arrhythmia during bupropion use.
    Acta obstetricia et gynecologica Scandinavica, 2010, Volume: 89, Issue:7

    Topics: Adult; Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Atrial Premature Complexes; B

2010
ECG conduction delays associated with massive bupropion overdose.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Bupropion; Delirium; Drug Ove

1998