Page last updated: 2024-10-17

bupropion and Anhedonia

bupropion has been researched along with Anhedonia in 4 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).

Research Excerpts

ExcerptRelevanceReference
"Taken together, these results in rats suggest that rapid hypoglycemia can induce an anhedonic state characterized by impaired consummatory responses to nutritional incentive stimuli and that can be alleviated by the antidepressant bupropion."8.02Evidence of hypoglycemic anhedonia and modulation by bupropion in rats. ( Ayoub, S; Horman, T; Leri, F, 2021)
"As part of a randomized controlled trial of smoking cessation therapies, 1122 adults (58% female) were assigned to: placebo (n = 131), bupropion (alone or with nicotine lozenge; n = 401), or nicotine replacement therapy (NRT; lozenge, patch, both; n = 590)."5.24Anhedonia: Its Dynamic Relations With Craving, Negative Affect, and Treatment During a Quit Smoking Attempt. ( Baker, TB; Chu, W; Cook, JW; Lanza, ST; Piper, ME, 2017)
"Taken together, these results in rats suggest that rapid hypoglycemia can induce an anhedonic state characterized by impaired consummatory responses to nutritional incentive stimuli and that can be alleviated by the antidepressant bupropion."4.02Evidence of hypoglycemic anhedonia and modulation by bupropion in rats. ( Ayoub, S; Horman, T; Leri, F, 2021)
"Bupropion is a dopaminergic and noradrenergic reuptake inhibitor and is not reported to cause emotional blunting."2.84Bupropion Administration Increases Resting-State Functional Connectivity in Dorso-Medial Prefrontal Cortex. ( Dean, Z; McCabe, C; Rzepa, E, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Kurogi, K1
Taniguchi, F1
Matsuo, R1
Shinozuka, M1
Suzaki, R1
Yasuo, S1
Horman, T1
Ayoub, S1
Leri, F1
Rzepa, E1
Dean, Z1
McCabe, C1
Cook, JW1
Lanza, ST1
Chu, W1
Baker, TB1
Piper, ME1

Trials

2 trials available for bupropion and Anhedonia

ArticleYear
Bupropion Administration Increases Resting-State Functional Connectivity in Dorso-Medial Prefrontal Cortex.
    The international journal of neuropsychopharmacology, 2017, 06-01, Volume: 20, Issue:6

    Topics: Affect; Amygdala; Anhedonia; Brain Mapping; Bupropion; Cerebrovascular Circulation; Cross-Over Studi

2017
Anhedonia: Its Dynamic Relations With Craving, Negative Affect, and Treatment During a Quit Smoking Attempt.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2017, Jun-01, Volume: 19, Issue:6

    Topics: Adult; Anhedonia; Bupropion; Craving; Female; Humans; Male; Nicotine; Smoking Cessation; Substance W

2017

Other Studies

2 other studies available for bupropion and Anhedonia

ArticleYear
Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: Anhedonia; Animals; Brain; Bupropion; Depression; Dopamine; Female; Housing; Male; Mice; Norepinephr

2023
Evidence of hypoglycemic anhedonia and modulation by bupropion in rats.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 203

    Topics: Anhedonia; Animals; Antidepressive Agents, Second-Generation; Appetitive Behavior; Bupropion; Deoxyg

2021